Senescence and aging: Causes, consequences, and therapeutic avenues

Journal of Cell Biology

Volumn 217, Issue 1, 2018, Pages 65-77

  McHugh, Domhnall ^a,b   Gil, Jesús ^a,b  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ARF PROTEIN; CELL PROTEIN; CYCLIN DEPENDENT KINASE INHIBITOR; PROTEIN P53; SENESCENCE ASSOCIATED SECRETORY PHENOTYPE; UNCLASSIFIED DRUG;

AGING; AUTOPHAGY; BYSTANDER EFFECT; CACHEXIA; CARDIOVASCULAR DISEASE; CELL AGING; CELL CYCLE ARREST; CELL FUNCTION; FIBROSING ALVEOLITIS; GENOMIC INSTABILITY; GROWTH INHIBITION; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNOPATHOLOGY; INFLAMMATION; KIDNEY DYSFUNCTION; LIFE EXTENSION; METABOLIC DISORDER; MULTIPOTENT STEM CELL; MUSCLE STEM CELL; NEURAL STEM CELL; NON INSULIN DEPENDENT DIABETES MELLITUS; NONALCOHOLIC FATTY LIVER; NONHUMAN; OSTEOARTHRITIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PROTEIN HOMEOSTASIS; REVIEW; SARCOPENIA; SENESCENCE; SIGNAL TRANSDUCTION; STEM CELL SELF-RENEWAL; TISSUE INJURY; ANIMAL; GENETICS; MOUSE; PATHOLOGY; PHYSIOLOGY; TELOMERE; TELOMERE HOMEOSTASIS;

AGING; ANIMALS; CELLULAR SENESCENCE; HUMANS; MICE; TELOMERE; TELOMERE HOMEOSTASIS;

EID: 85039857961     PISSN: 00219525     EISSN: 15408140     Source Type: Journal    
DOI: 10.1083/jcb.201708092     Document Type: Review

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