Rejuvenating senescent and centenarian human cells by reprogramming through the pluripotent state

Genes and Development

Volumn 25, Issue 21, 2011, Pages 2248-2253

  Lapasset, Laure ^a   Milhavet, Ollivier ^a,b   Prieur, Alexandre ^a   Besnard, Emilie ^a   Babled, Amelie ^a   Ät Hamou, Nafissa ^a   Leschik, Julia ^a   Pellestor, Franck ^c   Ramirez, Jean Marie ^d   De Vos, John ^d   Lehmann, Sylvain ^b   Lemaitre, Jean Marc ^a  

^a INSTITUT DE GÉNOMIQUE FONCTIONNELLE   (France)

^b INSTITUTE OF HUMAN GENETICS   (France)

^c HÔPITAL ARNAUD DE VILLENEUVE   (France)

^d HÔPITAL SAINT ELOI   (France)

Author keywords

Aging; Ipsc; Rejuvenation; Reprogramming; Senescence

Indexed keywords

BETA GALACTOSIDASE; TRANSCRIPTION FACTOR NANOG;

AGING; ARTICLE; CELL AGING; CELL DIFFERENTIATION; EMBRYONIC STEM CELL; FIBROBLAST; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; LONGEVITY; MICROARRAY ANALYSIS; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; OXIDATIVE STRESS; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; REGENERATIVE MEDICINE; SENESCENCE; SOMATIC CELL; TELOMERE;

AGED; AGED, 80 AND OVER; ANIMALS; CELL AGING; CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MICE; MICE, INBRED NOD; MICE, SCID; MITOCHONDRIA; NUCLEAR REPROGRAMMING; REJUVENATION; TELOMERE; TRANSCRIPTION FACTORS;

EID: 80455144472     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.173922.111     Document Type: Article

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