Pancreatic beta cell senescence contributes to the pathogenesis of type 2 diabetes in high-fat diet-induced diabetic mice

Diabetologia

Volumn 48, Issue 1, 2005, Pages 58-67

  Sone, H ^a   Kagawa, Y ^a,b  

^a KAGAWA NUTRITION UNIVERSITY   (Japan)

^b JICHI MEDICAL UNIVERSITY   (Japan)

Author keywords

Cellular proliferation; Cellular senescence; High fat diet; Pancreatic beta cell; Type 2 diabetes

Indexed keywords

BETA GALACTOSIDASE; INSULIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DENSITY; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; GLUCOSE TOLERANCE TEST; HISTOCHEMISTRY; INSULIN BLOOD LEVEL; LIPID DIET; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET BETA CELL; PATHOGENESIS; PRIORITY JOURNAL; SENESCENCE; STATISTICAL SIGNIFICANCE;

ANIMALS; AREA UNDER CURVE; BLOOD GLUCOSE; CELL AGING; CELL DIVISION; CHOLESTEROL; DIABETES MELLITUS, TYPE 2; DIETARY FATS; FATTY ACIDS, NONESTERIFIED; GLUCOSE TOLERANCE TEST; INSULIN; ISLETS OF LANGERHANS; MALE; MICE; MICE, INBRED C57BL;

EID: 12944320856     PISSN: 0012186X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00125-004-1605-2     Document Type: Article

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