-
1
-
-
72949096792
-
Senescence in tumours: Evidence from mice and humans
-
Collado, M. & Serrano, M. Senescence in tumours: evidence from mice and humans. Nature Rev. Cancer 10, 51-57 (2010).
-
(2010)
Nature Rev. Cancer
, vol.10
, pp. 51-57
-
-
Collado, M.1
Serrano, M.2
-
2
-
-
23244460597
-
Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
-
Chen, Z. et al. Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis. Nature 436, 725-730 (2005).
-
(2005)
Nature
, vol.436
, pp. 725-730
-
-
Chen, Z.1
-
3
-
-
23244461708
-
Oncogene-induced senescence as an initial barrier in lymphoma development
-
Braig, M. et al. Oncogene-induced senescence as an initial barrier in lymphoma development. Nature 436, 660-665 (2005).
-
(2005)
Nature
, vol.436
, pp. 660-665
-
-
Braig, M.1
-
4
-
-
84880328546
-
Senescent cells spread the word: Non-cell autonomous propagation of cellular senescence
-
Tasdemir, N. & Lowe, S. W. Senescent cells spread the word: non-cell autonomous propagation of cellular senescence. EMBO J. 32, 1975-1976 (2013).
-
(2013)
EMBO J.
, vol.32
, pp. 1975-1976
-
-
Tasdemir, N.1
Lowe, S.W.2
-
5
-
-
84881399206
-
A complex secretory program orchestrated by the inflammasome controls paracrine senescence
-
Acosta, J. C. et al. A complex secretory program orchestrated by the inflammasome controls paracrine senescence. Nature Cell Biol. 15, 978-990 (2013).
-
(2013)
Nature Cell Biol.
, vol.15
, pp. 978-990
-
-
Acosta, J.C.1
-
6
-
-
70350125106
-
Cell surface-bound IL-1α is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network
-
Orjalo, A. V., Bhaumik, D., Gengler, B. K., Scott, G. K. & Campisi, J. Cell surface-bound IL-1α is an upstream regulator of the senescence-associated IL-6/IL-8 cytokine network. Proc. Natl Acad. Sci. USA 106, 17031-17036 (2009).
-
(2009)
Proc. Natl Acad. Sci. USA
, vol.106
, pp. 17031-17036
-
-
Orjalo, A.V.1
Bhaumik, D.2
Gengler, B.K.3
Scott, G.K.4
Campisi, J.5
-
7
-
-
77949737971
-
A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis
-
Alimonti, A. et al. A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis. J. Clin. Invest. 120, 681-693 (2010).
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 681-693
-
-
Alimonti, A.1
-
8
-
-
84858785703
-
Coordinated regulation of myeloid cells by tumours
-
Gabrilovich, D. I., Ostrand-Rosenberg, S. & Bronte, V. Coordinated regulation of myeloid cells by tumours. Nature Rev. Immunol. 12, 253-268 (2012).
-
(2012)
Nature Rev. Immunol.
, vol.12
, pp. 253-268
-
-
Gabrilovich, D.I.1
Ostrand-Rosenberg, S.2
Bronte, V.3
-
9
-
-
33846937033
-
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
-
Xue, W. et al. Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas. Nature 445, 656-660 (2007).
-
(2007)
Nature
, vol.445
, pp. 656-660
-
-
Xue, W.1
-
10
-
-
81855169964
-
Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
-
Kang, T. W. et al. Senescence surveillance of pre-malignant hepatocytes limits liver cancer development. Nature 479, 547-551 (2011).
-
(2011)
Nature
, vol.479
, pp. 547-551
-
-
Kang, T.W.1
-
11
-
-
84874192617
-
T-helper-1-cell cytokines drive cancer into senescence
-
Braumüller, H. et al. T-helper-1-cell cytokines drive cancer into senescence. Nature 494, 361-365 (2013).
-
(2013)
Nature
, vol.494
, pp. 361-365
-
-
Braumüller, H.1
-
12
-
-
4243110417
-
Pten dose dictates cancer progression in the prostate
-
Trotman, L. C. et al. Pten dose dictates cancer progression in the prostate. PLoS Biol. 1, e59 (2003).
-
(2003)
PLoS Biol.
, vol.1
, pp. e59
-
-
Trotman, L.C.1
-
14
-
-
84892693674
-
A paracrine network regulates the cross-talk between human lung stem cells and the stroma
-
Ruiz, E. J., Oeztuerk-Winder, F. & Ventura, J. J. A paracrine network regulates the cross-talk between human lung stem cells and the stroma. Nature Commun. 5, 3175 (2014).
-
(2014)
Nature Commun.
, vol.5
, pp. 3175
-
-
Ruiz, E.J.1
Oeztuerk-Winder, F.2
Ventura, J.J.3
-
15
-
-
0030778204
-
Effective intercellular communication distances are determined by the relative time constants for cyto/chemokine secretion and diffusion
-
Francis, K. & Palsson, B. O. Effective intercellular communication distances are determined by the relative time constants for cyto/chemokine secretion and diffusion. Proc. Natl Acad. Sci. USA 94, 12258-12262 (1997).
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 12258-12262
-
-
Francis, K.1
Palsson, B.O.2
-
16
-
-
39849100541
-
Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: Role of bone marrow-derived myelomonocytic cells
-
Ahn, G. O. & Brown, J. M. Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cells. Cancer Cell 13, 193-205 (2008).
-
(2008)
Cancer Cell
, vol.13
, pp. 193-205
-
-
Ahn, G.O.1
Brown, J.M.2
-
17
-
-
77953914366
-
Tumor-induced tolerance and immune suppression depend on the C/EBPβ transcription factor
-
Marigo, I. et al. Tumor-induced tolerance and immune suppression depend on the C/EBPβ transcription factor. Immunity 32, 790-802 (2010).
-
(2010)
Immunity
, vol.32
, pp. 790-802
-
-
Marigo, I.1
-
18
-
-
77954069855
-
Isolation, cultivation and characterization of adult murine prostate stem cells
-
Lukacs, R. U., Goldstein, A. S., Lawson, D. A., Cheng, D. & Witte, O. N. Isolation, cultivation and characterization of adult murine prostate stem cells. Nature Protocols 5, 702-713 (2010).
-
(2010)
Nature Protocols
, vol.5
, pp. 702-713
-
-
Lukacs, R.U.1
Goldstein, A.S.2
Lawson, D.A.3
Cheng, D.4
Witte, O.N.5
-
19
-
-
0032482168
-
Production of mice deficient in genes for interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 receptor antagonist shows that IL-1β is crucial in turpentine-induced fever development and glucocorticoid secretion
-
Horai, R. et al. Production of mice deficient in genes for interleukin (IL)-1α, IL-1β, IL-1α/β, and IL-1 receptor antagonist shows that IL-1β is crucial in turpentine-induced fever development and glucocorticoid secretion. J. Exp. Med. 187, 1463-1475 (1998).
-
(1998)
J. Exp. Med.
, vol.187
, pp. 1463-1475
-
-
Horai, R.1
-
20
-
-
80053197541
-
Interleukin-1 receptor antagonist modulates the early phase of liver regeneration after partial hepatectomy in mice
-
Sgroi, A. et al. Interleukin-1 receptor antagonist modulates the early phase of liver regeneration after partial hepatectomy in mice. PLoS ONE 6, e25442 (2011).
-
(2011)
PLoS ONE
, vol.6
, pp. e25442
-
-
Sgroi, A.1
-
21
-
-
77952311605
-
Uncovering an IL-10-dependent NF-κB recruitment to the IL-1ra promoter that is impaired in STAT3 functionally defective patients
-
Tamassia, N. et al. Uncovering an IL-10-dependent NF-κB recruitment to the IL-1ra promoter that is impaired in STAT3 functionally defective patients. FASEB J. 24, 1365-1375 (2010).
-
(2010)
FASEB J.
, vol.24
, pp. 1365-1375
-
-
Tamassia, N.1
-
22
-
-
33644876537
-
The identification of senescence-specific genes during the induction of senescence in prostate cancer cells
-
Schwarze, S. R., Fu, V. X., Desotelle, J. A., Kenowski, M. L. & Jarrard, D. F. The identification of senescence-specific genes during the induction of senescence in prostate cancer cells. Neoplasia 7, 816-823 (2005).
-
(2005)
Neoplasia
, vol.7
, pp. 816-823
-
-
Schwarze, S.R.1
Fu, V.X.2
Desotelle, J.A.3
Kenowski, M.L.4
Jarrard, D.F.5
-
23
-
-
23244447893
-
Tumour biology: Senescence in premalignant tumours
-
Collado, M. et al. Tumour biology: senescence in premalignant tumours. Nature 436, 642 (2005).
-
(2005)
Nature
, vol.436
, pp. 642
-
-
Collado, M.1
-
24
-
-
61349100687
-
Myeloid-derived suppressor cells as regulators of the immune system
-
Gabrilovich, D. I. & Nagaraj, S. Myeloid-derived suppressor cells as regulators of the immune system. Nature Rev. Immunol. 9, 162-174 (2009).
-
(2009)
Nature Rev. Immunol.
, vol.9
, pp. 162-174
-
-
Gabrilovich, D.I.1
Nagaraj, S.2
-
25
-
-
77958590185
-
Therapy-induced senescence in cancer
-
Ewald, J. A., Desotelle, J. A., Wilding, G. & Jarrard, D. F. Therapy-induced senescence in cancer. J. Natl. Cancer Inst. 102, 1536-1546 (2010).
-
(2010)
J. Natl. Cancer Inst.
, vol.102
, pp. 1536-1546
-
-
Ewald, J.A.1
Desotelle, J.A.2
Wilding, G.3
Jarrard, D.F.4
-
26
-
-
84870659824
-
An immunohistochemical signature comprising PTEN, MYC, and Ki67 predicts progression in prostate cancer patients receiving adjuvant docetaxel after prostatectomy
-
Antonarakis, E. S. et al. An immunohistochemical signature comprising PTEN, MYC, and Ki67 predicts progression in prostate cancer patients receiving adjuvant docetaxel after prostatectomy. Cancer 118, 6063-6071 (2012).
-
(2012)
Cancer
, vol.118
, pp. 6063-6071
-
-
Antonarakis, E.S.1
-
27
-
-
0033764030
-
ARF) and is amplified in a subset of human breast cancers
-
ARF) and is amplified in a subset of human breast cancers. Nature Genet. 26, 291-299 (2000).
-
(2000)
Nature Genet.
, vol.26
, pp. 291-299
-
-
Jacobs, J.J.1
-
28
-
-
0035252089
-
Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes
-
Romanov, S. R. et al. Normal human mammary epithelial cells spontaneously escape senescence and acquire genomic changes. Nature 409, 633-637 (2001).
-
(2001)
Nature
, vol.409
, pp. 633-637
-
-
Romanov, S.R.1
-
29
-
-
12144289681
-
A large-scale RNAi screen in human cells identifies new components of the p53 pathway
-
Berns, K. et al. A large-scale RNAi screen in human cells identifies new components of the p53 pathway. Nature 428, 431-437 (2004).
-
(2004)
Nature
, vol.428
, pp. 431-437
-
-
Berns, K.1
-
30
-
-
77951765345
-
Subtle variations in Pten dose determine cancer susceptibility
-
Alimonti, A. et al. Subtle variations in Pten dose determine cancer susceptibility. Nature Genet. 42, 454-458 (2010).
-
(2010)
Nature Genet.
, vol.42
, pp. 454-458
-
-
Alimonti, A.1
-
31
-
-
84884994218
-
The Cancer Genome Atlas Pan-Cancer analysis project
-
The Cancer Genome Atlas Research Network. The Cancer Genome Atlas Pan-Cancer analysis project. Nature Genet. 45, 1113-1120 (2013).
-
(2013)
Nature Genet.
, vol.45
, pp. 1113-1120
-
-
|