메뉴 건너뛰기




Volumn 97, Issue 4, 1999, Pages 527-538

p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; TELOMERASE;

EID: 0033553516     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(00)80762-X     Document Type: Article
Times cited : (844)

References (44)
  • 3
    • 0029097759 scopus 로고
    • Radiation-induced cell cycle arrest compromised by p21 deficiency
    • Brugarolas, J., Chandrasekaran, C., Gordon, J.I., Beach, D., Jacks, T., and Hannon, G.J. (1995). Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature 377, 552-557.
    • (1995) Nature , vol.377 , pp. 552-557
    • Brugarolas, J.1    Chandrasekaran, C.2    Gordon, J.I.3    Beach, D.4    Jacks, T.5
  • 4
    • 0029162563 scopus 로고
    • Telomere elongation in immortal human cells without detectable telomerase activity
    • Bryan, T.M., Englezou, A., Gupta, J., Bacchetti, S., and Reddel, R.R. (1995). Telomere elongation in immortal human cells without detectable telomerase activity. EMBO 14, 4240-4248.
    • (1995) EMBO , vol.14 , pp. 4240-4248
    • Bryan, T.M.1    Englezou, A.2    Gupta, J.3    Bacchetti, S.4    Reddel, R.R.5
  • 6
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • Counter, C.M., Avilion, A.A., LeFeuvre, C.E., Stewart, N.G., Greider, C.W., Harley, C.B., and Bacchetti, S. (1992). Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO 11, 1921-1929.
    • (1992) EMBO , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    LeFeuvre, C.E.3    Stewart, N.G.4    Greider, C.W.5    Harley, C.B.6    Bacchetti, S.7
  • 9
    • 0030898436 scopus 로고    scopus 로고
    • Transgenic mouse model for studying the transcriptional activity of the p53 protein: Age- and tissue-dependent changes in radiation-induced activation during embryogenesis
    • Gottlieb, E., Haffner, R., King, A., Asher, G., Gruss, P., Lonai, P., and Oren, M. (1997). Transgenic mouse model for studying the transcriptional activity of the p53 protein: Age- and tissue-dependent changes in radiation-induced activation during embryogenesis. EMBO 16, 1381-1390.
    • (1997) EMBO , vol.16 , pp. 1381-1390
    • Gottlieb, E.1    Haffner, R.2    King, A.3    Asher, G.4    Gruss, P.5    Lonai, P.6    Oren, M.7
  • 11
    • 0032567975 scopus 로고    scopus 로고
    • Telomeres and senescence: The history, the experiment, the future
    • Greider, C.W. (1998). Telomeres and senescence: The history, the experiment, the future. Curr. Biol. 8, 178-181.
    • (1998) Curr. Biol. , vol.8 , pp. 178-181
    • Greider, C.W.1
  • 12
    • 0024978857 scopus 로고
    • A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
    • Greider, C.W., and Blackburn, E.H. (1989). A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis. Nature 337, 331-337.
    • (1989) Nature , vol.337 , pp. 331-337
    • Greider, C.W.1    Blackburn, E.H.2
  • 13
    • 0026055983 scopus 로고
    • Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of life span in human diploid fibroblasts, TIG-1
    • Hara, E., Tsurui, H., Shinozaki, A., Nakada, S., and Oda, K. (1991). Cooperative effect of antisense-Rb and antisense-p53 oligomers on the extension of life span in human diploid fibroblasts, TIG-1. Biochem. Biophys. Res. Comm. 179, 528-534.
    • (1991) Biochem. Biophys. Res. Comm. , vol.179 , pp. 528-534
    • Hara, E.1    Tsurui, H.2    Shinozaki, A.3    Nakada, S.4    Oda, K.5
  • 15
    • 0344622606 scopus 로고
    • The serial cultivation of human diploid cell strains
    • Hayflick, L., and Moorhead, P.S. (1961). The serial cultivation of human diploid cell strains. Exp. Cell. Res. 25, 585-621.
    • (1961) Exp. Cell. Res. , vol.25 , pp. 585-621
    • Hayflick, L.1    Moorhead, P.S.2
  • 16
    • 0033104511 scopus 로고    scopus 로고
    • -/- embryos is associated with failure to close the neural tube
    • -/- embryos is associated with failure to close the neural tube. EMBO J. 18, 1172-1181.
    • (1999) EMBO J. , vol.18 , pp. 1172-1181
    • Herrera, E.1    Samper, E.2    Blasco, M.A.3
  • 18
    • 0033605145 scopus 로고    scopus 로고
    • p53 and ATM dependent apoptosis induced by telomeres lacking TRF2
    • Karleseder, J., Broccoli, D., Dai, Y., Hardy, S., and de Lange, T. (1999). p53 and ATM dependent apoptosis induced by telomeres lacking TRF2. Science 283, 1321-1325.
    • (1999) Science , vol.283 , pp. 1321-1325
    • Karleseder, J.1    Broccoli, D.2    Dai, Y.3    Hardy, S.4    De Lange, T.5
  • 22
    • 0020520516 scopus 로고
    • Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes
    • Land, H., Parada, L.F., and Weinberg, R.A. (1983). Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes. Nature 304, 596-602.
    • (1983) Nature , vol.304 , pp. 596-602
    • Land, H.1    Parada, L.F.2    Weinberg, R.A.3
  • 24
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine, A.J. (1997). p53, the cellular gatekeeper for growth and division. Cell 88, 323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 25
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe, S.W., Ruley, H.E., Jacks, T., and Housman, D.E. (1993). p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74, 957-967.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 26
    • 0027266758 scopus 로고
    • An alternative pathway for yeast telomere maintenance rescues est1- senescence
    • Lundblad, V., and Blackburn, E.H. (1993). An alternative pathway for yeast telomere maintenance rescues est1- senescence. Cell 73, 347-360.
    • (1993) Cell , vol.73 , pp. 347-360
    • Lundblad, V.1    Blackburn, E.H.2
  • 27
    • 0029746495 scopus 로고    scopus 로고
    • Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase
    • McEachern, M.J., and Blackburn, E.H. (1996). Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase. Genes Dev. 10, 1822-1834.
    • (1996) Genes Dev. , vol.10 , pp. 1822-1834
    • McEachern, M.J.1    Blackburn, E.H.2
  • 28
    • 0026693776 scopus 로고
    • Myc family oncoproteins function through a common pathway to transform normal cells in culture: Cross-interference by Max and transacting dominant mutants
    • Mukherjee, B., Morgenbesser, S.D., and DePinho, R.A. (1992). Myc family oncoproteins function through a common pathway to transform normal cells in culture: Cross-interference by Max and transacting dominant mutants. Genes Dev. 6, 1480-1492.
    • (1992) Genes Dev. , vol.6 , pp. 1480-1492
    • Mukherjee, B.1    Morgenbesser, S.D.2    DePinho, R.A.3
  • 31
    • 0032475878 scopus 로고    scopus 로고
    • Signaling to p53: Breaking the MDM2-p53 circuit
    • Prives, C. (1998). Signaling to p53: Breaking the MDM2-p53 circuit. Cell 95, 5-8.
    • (1998) Cell , vol.95 , pp. 5-8
    • Prives, C.1
  • 33
    • 0031879115 scopus 로고    scopus 로고
    • Telomere length dynamics in human lymphocyte sub-populations measured by flow cytometry
    • Rufer, N., Dragowska, W., Thornbury, G., Roosnek, E., and Lansdorp, P.M. (1998). Telomere length dynamics in human lymphocyte sub-populations measured by flow cytometry. Nat. Biotechnol. 16, 743-747.
    • (1998) Nat. Biotechnol. , vol.16 , pp. 743-747
    • Rufer, N.1    Dragowska, W.2    Thornbury, G.3    Roosnek, E.4    Lansdorp, P.M.5
  • 35
    • 0027421043 scopus 로고
    • Loss of a yeast telomere: Arrest, recovery, and chromosome loss
    • Sandell, L.L., and Zakian, V.A. (1993). Loss of a yeast telomere: Arrest, recovery, and chromosome loss. Cell 75, 729-739.
    • (1993) Cell , vol.75 , pp. 729-739
    • Sandell, L.L.1    Zakian, V.A.2
  • 37
    • 0026054961 scopus 로고
    • A role for both RB and p53 in the regulation of human cellular senescence
    • Shay, J.W., Pereira-Smith, O., and Wright, W.E. (1991). A role for both RB and p53 in the regulation of human cellular senescence. Exp. Cell Res. 196, 33-39.
    • (1991) Exp. Cell Res. , vol.196 , pp. 33-39
    • Shay, J.W.1    Pereira-Smith, O.2    Wright, W.E.3
  • 38
    • 0030667702 scopus 로고    scopus 로고
    • DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2
    • Shieh, S.Y., Ikeda, M., Taya, Y., and Prives, C. (1997). DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell 91, 325-334.
    • (1997) Cell , vol.91 , pp. 325-334
    • Shieh, S.Y.1    Ikeda, M.2    Taya, Y.3    Prives, C.4
  • 40
    • 0031027618 scopus 로고    scopus 로고
    • Control of telomere length by the human telomeric protein TRF1
    • van Steensel, B., and de Lange, T. (1997). Control of telomere length by the human telomeric protein TRF1. Nature 385, 740-743.
    • (1997) Nature , vol.385 , pp. 740-743
    • Van Steensel, B.1    De Lange, T.2
  • 41
    • 0032489012 scopus 로고    scopus 로고
    • TRF2 protects human telomeres from end-to-end fusions
    • van Steensel, B., Smogorzewska, A., and de Lange, T. (1998). TRF2 protects human telomeres from end-to-end fusions. Cell 92, 401-413.
    • (1998) Cell , vol.92 , pp. 401-413
    • Van Steensel, B.1    Smogorzewska, A.2    De Lange, T.3
  • 42
    • 0032567967 scopus 로고    scopus 로고
    • Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span
    • Vaziri, H., and Benchimol, S. (1998). Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span. Curr. Biol. 8, 279-282.
    • (1998) Curr. Biol. , vol.8 , pp. 279-282
    • Vaziri, H.1    Benchimol, S.2
  • 43
    • 0032541321 scopus 로고    scopus 로고
    • Retention of wild-type p53 in tumors from p53 heterozygous mice: Reduction of p53 dosage can promote cancer formation
    • Venkatachalam, S., Shi, Y.P., Jones, S.N., Vogel, H., Bradley, A., Pinkel, D., and Donehower, L.A. (1998). Retention of wild-type p53 in tumors from p53 heterozygous mice: Reduction of p53 dosage can promote cancer formation. EMBO 17, 4657-4667.
    • (1998) EMBO , vol.17 , pp. 4657-4667
    • Venkatachalam, S.1    Shi, Y.P.2    Jones, S.N.3    Vogel, H.4    Bradley, A.5    Pinkel, D.6    Donehower, L.A.7
  • 44
    • 0025279059 scopus 로고
    • In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase
    • Yu, G.L., Bradley, J.D., Attardi, L.D., and Blackburn, E.H. (1990). In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase. Nature 344, 126-132.
    • (1990) Nature , vol.344 , pp. 126-132
    • Yu, G.L.1    Bradley, J.D.2    Attardi, L.D.3    Blackburn, E.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.