'Super p53' mice exhibit enhanced DNA damage response, are tumor resistant and age normally

EMBO Journal

Volumn 21, Issue 22, 2002, Pages 6225-6235

  García Cao, Isabel ^a   García Cao, Marta ^a   Martín Caballero, Juan ^b   Criado, Luis M ^a   Klatt, Peter ^a   Flores, Juana M ^c   Weill, Jean Claude ^d   Blasco, María A ^a   Serrano, Manuel ^a  

^a CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

^b Molecular Pathology Program   (Spain)

^c UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^d INSERM   (France)

Author keywords

Aging; Animal models; DNA damage; P53; Tumor suppression

Indexed keywords

PROTEIN P53;

AGING; ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; DNA DAMAGE; DNA MODIFICATION; FEMALE; GENE CONTROL; GENE FUNCTION; GENETIC CODE; MOUSE; NONHUMAN; NULL ALLELE; PRIORITY JOURNAL; TRANSGENE; TRANSGENIC MOUSE; TUMOR RESISTANCE;

AGING; ANIMALS; CELL CYCLE; CELLS, CULTURED; CROSSES, GENETIC; DNA DAMAGE; FEMALE; FERTILITY; FIBROBLASTS; FIBROSARCOMA; GENE EXPRESSION REGULATION; GENES, P53; GENETIC COMPLEMENTATION TEST; GENETIC PREDISPOSITION TO DISEASE; IMMUNITY, NATURAL; LONGEVITY; MALE; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, KNOCKOUT; MICE, TRANSGENIC; TRANSGENES; TUMOR SUPPRESSOR PROTEIN P53; URINARY BLADDER NEOPLASMS;

ANIMALIA; MUS MUSCULUS;

EID: 0037112844     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf595     Document Type: Article

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