Targeting senescent cells enhances adipogenesis and metabolic function in old age

eLife

Volumn 4, Issue DECEMBER2015, 2015, Pages

  Xu, Ming ^a   Palmer, Allyson K ^a   Ding, Husheng ^a   Weivoda, Megan M ^a   Pirtskhalava, Tamar ^a   White, Thomas A ^a   Sepe, Anna ^a   Johnson, Kurt O ^a   Stout, Michael B ^a   Giorgadze, Nino ^a   Jensen, Michael D ^a   LeBrasseur, Nathan K ^a   Tchkonia, Tamar ^a   Kirkland, James L ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; ACTIVIN A; CASPASE 8; CCAAT ENHANCER BINDING PROTEIN ALPHA; FATTY ACID BINDING PROTEIN 4; FK 506 BINDING PROTEIN; JANUS KINASE INHIBITOR; MESSENGER RNA; PERILIPIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; REACTIVE OXYGEN METABOLITE; RUXOLITINIB; TRIACYLGLYCEROL; ACTIVIN;

ADIPOGENESIS; ADULT; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BODY WEIGHT; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; INSULIN SENSITIVITY; LIPID STORAGE; LIPODYSTROPHY; MALE; MOUSE; MYRISTYLATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHENOTYPE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SENESCENCE; TISSUE METABOLISM; TRANSCRIPTION REGULATION; WESTERN BLOTTING; ANIMAL; CELL AGING; PHYSIOLOGY; SECRETION (PROCESS); STEM CELL;

ACTIVINS; ADIPOGENESIS; ANIMALS; CELL AGING; HUMANS; MICE; STEM CELLS;

EID: 84988603034     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.12997     Document Type: Article

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