SIRT6 deacetylates H3K18ac at pericentric chromatin to prevent mitotic errors and cellular senescence

Nature Structural and Molecular Biology

Volumn 23, Issue 5, 2016, Pages 434-440

  Tasselli, Luisa ^a,b   Xi, Yuanxin ^c   Zheng, Wei ^a,b   Tennen, Ruth I ^a   Odrowaz, Zaneta ^a,b   Simeoni, Federica ^a,b   Li, Wei ^c   Chua, Katrin F ^a,b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE H3; K 18; SIRTUIN 6; CHROMATIN; HISTONE; SIRT6 PROTEIN, HUMAN; SIRTUIN;

AGING; ARTICLE; CELL AGING; CELL FUNCTION; CENTROMERE; CHROMATIN; DEACETYLATION; GENE INACTIVATION; GENE SILENCING; GENETIC TRANSCRIPTION; GENOMIC INSTABILITY; HETEROCHROMATIN; HISTONE ACETYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MITOSIS; MOLECULAR PATHOLOGY; NUCLEOSOME; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RNA INTERFERENCE; ACETYLATION; CHEMISTRY; GENE EXPRESSION; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY; PROTEIN PROCESSING; TUMOR CELL LINE;

ACETYLATION; CELL AGING; CELL LINE, TUMOR; CHROMATIN; GENE EXPRESSION; GENE SILENCING; HEK293 CELLS; HISTONES; HUMANS; MITOSIS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SIRTUINS;

EID: 84962094354     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.3202     Document Type: Article

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