Cytoplasmic chromatin triggers inflammation in senescence and cancer

Nature

Volumn 550, Issue 7676, 2017, Pages

  Dou, Zhixun ^a   Ghosh, Kanad ^a   Vizioli, Maria Grazia ^b,c   Zhu, Jiajun ^a   Sen, Payel ^a   Wangensteen, Kirk J ^d   Simithy, Johayra ^a   Lan, Yemin ^a   Lin, Yanping ^a   Zhou, Zhuo ^e   Capell, Brian C ^a,f   Xu, Caiyue ^a   Xu, Mingang ^f   Kieckhaefer, Julia E ^a,d   Jiang, Tianying ^f   Shoshkes Carmel, Michal ^a,d   Al Tanim, K M Ahasan ^a   Barber, Glen N ^g   Seykora, John T ^f   Millar, Sarah E ^f   Kaestner, Klaus H ^a,d   Garcia, Benjamin A ^a   Adams, Peter D ^b,c,h   Berger, Shelley L ^a,d   more..

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e PEKING UNIVERSITY   (China)

^f UNIVERSITY OF PENNSYLVANIA   (United States)

^g UNIVERSITY OF MIAMI   (United States)

^h BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC GMP; DIMETHYL SULFOXIDE; GENOMIC DNA; INTERFERON; RAS PROTEIN; SYNTHETASE; CYTOKINE; MB21D1 PROTEIN, MOUSE; MEMBRANE PROTEIN; MPYS PROTEIN, MOUSE; NUCLEOTIDYLTRANSFERASE; PROTEIN P21;

CANCER; CELLS AND CELL COMPONENTS; CYTOPLASM; DNA; EGG; GENE; GENE EXPRESSION; IMMUNITY; PHENOTYPE; SENESCENCE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CAMP SIGNALING; CARCINOGENESIS; CHROMATIN; CHROMATIN IMMUNOPRECIPITATION; CHRONIC INFLAMMATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOKINE RELEASE; CYTOPLASM; CYTOSOL; DNA DAMAGE RESPONSE; FEMALE; GENE ACTIVATION; GENE EXPRESSION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMR-90 CELL LINE; INNATE IMMUNITY; IONIZING RADIATION; MALE; MALIGNANT NEOPLASM; MOLECULAR PATHOLOGY; MOUSE; NONHUMAN; ONCOGENE RAS; PRIMARY CELL; PRIORITY JOURNAL; SENESCENCE; TARGET CELL; WESTERN BLOTTING; ANIMAL; CELL AGING; DEFICIENCY; GENETICS; IMMUNOLOGY; INFLAMMATION; LIVER; METABOLISM; NEOPLASM; PATHOLOGY; SECRETION (PROCESS); TUMOR CELL LINE;

MUS;

ANIMALS; CELL LINE, TUMOR; CELLULAR SENESCENCE; CHROMATIN; CYTOKINES; CYTOPLASM; FEMALE; HUMANS; IMMUNITY, INNATE; INFLAMMATION; LIVER; MALE; MEMBRANE PROTEINS; MICE; NEOPLASMS; NUCLEOTIDYLTRANSFERASES; ONCOGENE PROTEIN P21(RAS); RADIATION, IONIZING;

EID: 85031901650     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature24050     Document Type: Article

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