-
1
-
-
85029668064
-
Myeloid cells in the central nervous system
-
Herz J, Filiano AJ, Smith A, Yogev N, Kipnis J. Myeloid cells in the central nervous system. Immunity (2017) 46:943-56. doi:10.1016/j.immuni.2017.06.007
-
(2017)
Immunity
, vol.46
, pp. 943-956
-
-
Herz, J.1
Filiano, A.J.2
Smith, A.3
Yogev, N.4
Kipnis, J.5
-
2
-
-
78149360132
-
Fate mapping analysis reveals that adult microglia derive from primitive macrophages
-
Ginhoux F, Greter M, Leboeuf M, Nandi S, See P, Gokhan S, et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science (2010) 330:841-5. doi:10.1126/science.1194637
-
(2010)
Science
, vol.330
, pp. 841-845
-
-
Ginhoux, F.1
Greter, M.2
Leboeuf, M.3
Nandi, S.4
See, P.5
Gokhan, S.6
-
3
-
-
84875892857
-
Microglia emerge from erythromyeloid precursors via Pu.1-and Irf8-dependent pathways
-
Kierdorf K, Erny D, Goldmann T, Sander V, Schulz C, Perdiguero EG, et al. Microglia emerge from erythromyeloid precursors via Pu.1-and Irf8-dependent pathways. Nat Neurosci (2013) 16:273-80. doi:10.1038/nn.3318
-
(2013)
Nat Neurosci
, vol.16
, pp. 273-280
-
-
Kierdorf, K.1
Erny, D.2
Goldmann, T.3
Sander, V.4
Schulz, C.5
Perdiguero, E.G.6
-
4
-
-
84869156976
-
Development and homeostasis of 'resident' myeloid cells: the case of the microglia
-
Gomez Perdiguero E, Schulz C, Geissmann F. Development and homeostasis of 'resident' myeloid cells: the case of the microglia. Glia (2013) 61:112-20. doi:10.1002/glia.22393
-
(2013)
Glia
, vol.61
, pp. 112-120
-
-
Gomez Perdiguero, E.1
Schulz, C.2
Geissmann, F.3
-
5
-
-
84857883847
-
Macrophage plasticity and polarization: in vivo veritas
-
Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest (2012) 122:787-95. doi:10.1172/JCI59643
-
(2012)
J Clin Invest
, vol.122
, pp. 787-795
-
-
Sica, A.1
Mantovani, A.2
-
6
-
-
77957157156
-
CSF-1, IGF-1, and the control of postnatal growth and development
-
Gow DJ, Sester DP, Hume DA. CSF-1, IGF-1, and the control of postnatal growth and development. J Leukoc Biol (2010) 88:475-81. doi:10.1189/jlb.0310158
-
(2010)
J Leukoc Biol
, vol.88
, pp. 475-481
-
-
Gow, D.J.1
Sester, D.P.2
Hume, D.A.3
-
7
-
-
63149088164
-
Trophic macrophages in development and disease
-
Pollard JW. Trophic macrophages in development and disease. Nat Rev Immunol (2009) 9:259-70. doi:10.1038/nri2528
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 259-270
-
-
Pollard, J.W.1
-
8
-
-
84942522549
-
Homeostasis of microglia in the adult brain: review of novel microglia depletion systems
-
Waisman A, Ginhoux F, Greter M, Bruttger J. Homeostasis of microglia in the adult brain: review of novel microglia depletion systems. Trends Immunol (2015) 36:625-36. doi:10.1016/j.it.2015.08.005
-
(2015)
Trends Immunol
, vol.36
, pp. 625-636
-
-
Waisman, A.1
Ginhoux, F.2
Greter, M.3
Bruttger, J.4
-
9
-
-
56149103896
-
Macrophage polarization in bacterial infections
-
Benoit M, Desnues B, Mege J-L. Macrophage polarization in bacterial infections. J Immunol (2008) 181:3733-9. doi:10.4049/jimmunol.181.6.3733
-
(2008)
J Immunol
, vol.181
, pp. 3733-3739
-
-
Benoit, M.1
Desnues, B.2
Mege, J.-L.3
-
10
-
-
0034698830
-
High mobility group 1 protein (Hmg-1) stimulates proinflammatory cytokine synthesis in human monocytes
-
Andersson U, Wang H, Palmblad K, Aveberger A-C, Bloom O, Erlandsson-Harris H, et al. High mobility group 1 protein (Hmg-1) stimulates proinflammatory cytokine synthesis in human monocytes. J Exp Med (2000) 192:565-70. doi:10.1084/jem.192.4.565
-
(2000)
J Exp Med
, vol.192
, pp. 565-570
-
-
Andersson, U.1
Wang, H.2
Palmblad, K.3
Aveberger, A.-C.4
Bloom, O.5
Erlandsson-Harris, H.6
-
11
-
-
22244464662
-
ATP mediates rapid microglial response to local brain injury in vivo
-
Davalos D, Grutzendler J, Yang G, Kim JV, Zuo Y, Jung S, et al. ATP mediates rapid microglial response to local brain injury in vivo. Nat Neurosci (2005) 8:752-8. doi:10.1038/nn1472
-
(2005)
Nat Neurosci
, vol.8
, pp. 752-758
-
-
Davalos, D.1
Grutzendler, J.2
Yang, G.3
Kim, J.V.4
Zuo, Y.5
Jung, S.6
-
12
-
-
19744380563
-
Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo
-
Nimmerjahn A, Kirchhoff F, Helmchen F. Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo. Science (2005) 308:1314-8. doi:10.1126/science.1110647
-
(2005)
Science
, vol.308
, pp. 1314-1318
-
-
Nimmerjahn, A.1
Kirchhoff, F.2
Helmchen, F.3
-
13
-
-
84867740805
-
Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
-
Gautier EL, Shay T, Miller J, Greter M, Jakubzick C, Ivanov S, et al. Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. Nat Immunol (2012) 13:1118-28. doi:10.1038/ni.2419
-
(2012)
Nat Immunol
, vol.13
, pp. 1118-1128
-
-
Gautier, E.L.1
Shay, T.2
Miller, J.3
Greter, M.4
Jakubzick, C.5
Ivanov, S.6
-
14
-
-
84894102230
-
Transcriptome-based network analysis reveals a spectrum model of human macrophage activation
-
Xue J, Schmidt SV, Sander J, Draffehn A, Krebs W, Quester I, et al. Transcriptome-based network analysis reveals a spectrum model of human macrophage activation. Immunity (2014) 40:274-88. doi:10.1016/j.immuni.2014.01.006
-
(2014)
Immunity
, vol.40
, pp. 274-288
-
-
Xue, J.1
Schmidt, S.V.2
Sander, J.3
Draffehn, A.4
Krebs, W.5
Quester, I.6
-
15
-
-
84942524460
-
Microglia: dynamic mediators of synapse development and plasticity
-
Wu Y, Dissing-Olesen L, MacVicar BA, Stevens B. Microglia: dynamic mediators of synapse development and plasticity. Trends Immunol (2015) 36:605-13. doi:10.1016/j.it.2015.08.008
-
(2015)
Trends Immunol
, vol.36
, pp. 605-613
-
-
Wu, Y.1
Dissing-Olesen, L.2
MacVicar, B.A.3
Stevens, B.4
-
16
-
-
80052633284
-
Synaptic pruning by microglia is necessary for normal brain development
-
Paolicelli RC, Bolasco G, Pagani F, Maggi L, Scianni M, Panzanelli P, et al. Synaptic pruning by microglia is necessary for normal brain development. Science (2011) 333:1456-8. doi:10.1126/science.1202529
-
(2011)
Science
, vol.333
, pp. 1456-1458
-
-
Paolicelli, R.C.1
Bolasco, G.2
Pagani, F.3
Maggi, L.4
Scianni, M.5
Panzanelli, P.6
-
17
-
-
84924368520
-
Tissue-resident macrophages: then and now
-
Davies LC, Taylor PR. Tissue-resident macrophages: then and now. Immunology (2015) 144:541-8. doi:10.1111/imm.12451
-
(2015)
Immunology
, vol.144
, pp. 541-548
-
-
Davies, L.C.1
Taylor, P.R.2
-
18
-
-
84884352076
-
Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes
-
Jakubzick C, Gautier EL, Gibbings SL, Sojka DK, Schlitzer A, Johnson TE, et al. Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes. Immunity (2013) 39:599-610. doi:10.1016/j.immuni.2013.08.007
-
(2013)
Immunity
, vol.39
, pp. 599-610
-
-
Jakubzick, C.1
Gautier, E.L.2
Gibbings, S.L.3
Sojka, D.K.4
Schlitzer, A.5
Johnson, T.E.6
-
19
-
-
84960354901
-
Tissue-resident macrophage ontogeny and homeostasis
-
Ginhoux F, Guilliams M. Tissue-resident macrophage ontogeny and homeostasis. Immunity (2016) 44:439-49. doi:10.1016/j.immuni.2016.02.024
-
(2016)
Immunity
, vol.44
, pp. 439-449
-
-
Ginhoux, F.1
Guilliams, M.2
-
20
-
-
84928189502
-
C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages
-
Hoeffel G, Chen J, Lavin Y, Low D, Almeida FF, See P, et al. C-Myb(+) erythro-myeloid progenitor-derived fetal monocytes give rise to adult tissue-resident macrophages. Immunity (2015) 42:665-78. doi:10.1016/j.immuni.2015.03.011
-
(2015)
Immunity
, vol.42
, pp. 665-678
-
-
Hoeffel, G.1
Chen, J.2
Lavin, Y.3
Low, D.4
Almeida, F.F.5
See, P.6
-
21
-
-
84963615042
-
Fetal HSCs versus EMP2s
-
Sheng J, Ruedl C, Karjalainen K. Fetal HSCs versus EMP2s. Immunity (2015) 43:1025. doi:10.1016/j.immuni.2015.11.023
-
(2015)
Immunity
, vol.43
, pp. 1025
-
-
Sheng, J.1
Ruedl, C.2
Karjalainen, K.3
-
22
-
-
84925465211
-
Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors
-
Gomez Perdiguero E, Klapproth K, Schulz C, Busch K, Azzoni E, Crozet L, et al. Tissue-resident macrophages originate from yolk-sac-derived erythro-myeloid progenitors. Nature (2015) 518:547-51. doi:10.1038/nature13989
-
(2015)
Nature
, vol.518
, pp. 547-551
-
-
Gomez Perdiguero, E.1
Klapproth, K.2
Schulz, C.3
Busch, K.4
Azzoni, E.5
Crozet, L.6
-
23
-
-
85018254376
-
Mice deficient in NRROS show abnormal microglial development and neurological disorders
-
Wong K, Noubade R, Manzanillo P, Ota N, Foreman O, Hackney JA, et al. Mice deficient in NRROS show abnormal microglial development and neurological disorders. Nat Immunol (2017) 18:633-41. doi:10.1038/ni.3743
-
(2017)
Nat Immunol
, vol.18
, pp. 633-641
-
-
Wong, K.1
Noubade, R.2
Manzanillo, P.3
Ota, N.4
Foreman, O.5
Hackney, J.A.6
-
24
-
-
0029002659
-
Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4+ T cells compared
-
Ford AL, Goodsall AL, Hickey WF, Sedgwick JD. Normal adult ramified microglia separated from other central nervous system macrophages by flow cytometric sorting. Phenotypic differences defined and direct ex vivo antigen presentation to myelin basic protein-reactive CD4+ T cells compared. J Immunol (1995) 154:4309-21
-
(1995)
J Immunol
, vol.154
, pp. 4309-4321
-
-
Ford, A.L.1
Goodsall, A.L.2
Hickey, W.F.3
Sedgwick, J.D.4
-
25
-
-
84962250196
-
New tools for studying microglia in the mouse and human CNS
-
Bennett ML, Bennett FC, Liddelow SA, Ajami B, Zamanian JL, Fernhoff NB, et al. New tools for studying microglia in the mouse and human CNS. Proc Natl Acad Sci U S A (2016) 113:E1738-46. doi:10.1073/pnas.1525528113
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. E1738-E1746
-
-
Bennett, M.L.1
Bennett, F.C.2
Liddelow, S.A.3
Ajami, B.4
Zamanian, J.L.5
Fernhoff, N.B.6
-
26
-
-
84855384345
-
The fractalkine receptor but not CCR2 is present on microglia from embryonic development throughout adulthood
-
Mizutani M, Pino PA, Saederup N, Charo IF, Ransohoff RM, Cardona AE. The fractalkine receptor but not CCR2 is present on microglia from embryonic development throughout adulthood. J Immunol (2012) 188:29-36. doi:10.4049/jimmunol.1100421
-
(2012)
J Immunol
, vol.188
, pp. 29-36
-
-
Mizutani, M.1
Pino, P.A.2
Saederup, N.3
Charo, I.F.4
Ransohoff, R.M.5
Cardona, A.E.6
-
27
-
-
33745573660
-
Control of microglial neurotoxicity by the fractalkine receptor
-
Cardona AE, Pioro EP, Sasse ME, Kostenko V, Cardona SM, Dijkstra IM, et al. Control of microglial neurotoxicity by the fractalkine receptor. Nat Neurosci (2006) 9:917-24. doi:10.1038/nn1715
-
(2006)
Nat Neurosci
, vol.9
, pp. 917-924
-
-
Cardona, A.E.1
Pioro, E.P.2
Sasse, M.E.3
Kostenko, V.4
Cardona, S.M.5
Dijkstra, I.M.6
-
28
-
-
0034028817
-
Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion
-
Jung S, Aliberti J, Graemmel P, Sunshine MJ, Kreutzberg GW, Sher A, et al. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol (2000) 20:4106-14. doi:10.1128/MCB.20.11.4106-4114.2000
-
(2000)
Mol Cell Biol
, vol.20
, pp. 4106-4114
-
-
Jung, S.1
Aliberti, J.2
Graemmel, P.3
Sunshine, M.J.4
Kreutzberg, G.W.5
Sher, A.6
-
29
-
-
84957554443
-
Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina
-
O'Koren EG, Mathew R, Saban DR. Fate mapping reveals that microglia and recruited monocyte-derived macrophages are definitively distinguishable by phenotype in the retina. Sci Rep (2016) 6:20636. doi:10.1038/srep20636
-
(2016)
Sci Rep
, vol.6
, pp. 20636
-
-
O'Koren, E.G.1
Mathew, R.2
Saban, D.R.3
-
31
-
-
84880658105
-
Regulation of adaptive immunity by the fractalkine receptor during autoimmune inflammation
-
Garcia JA, Pino PA, Mizutani M, Cardona SM, Charo IF, Ransohoff RM, et al. Regulation of adaptive immunity by the fractalkine receptor during autoimmune inflammation. J Immunol (2013) 191:1063-72. doi:10.4049/jimmunol.1300040
-
(2013)
J Immunol
, vol.191
, pp. 1063-1072
-
-
Garcia, J.A.1
Pino, P.A.2
Mizutani, M.3
Cardona, S.M.4
Charo, I.F.5
Ransohoff, R.M.6
-
32
-
-
85016469032
-
Deletion of the fractalkine receptor, CX3CR1, improves endogenous repair, axon sprouting, and synaptogenesis after spinal cord injury in mice
-
Freria CM, Hall JCE, Wei P, Guan Z, McTigue DM, Popovich PG. Deletion of the fractalkine receptor, CX3CR1, improves endogenous repair, axon sprouting, and synaptogenesis after spinal cord injury in mice. J Neurosci (2017) 37:3568-87. doi:10.1523/JNEUROSCI.2841-16.2017
-
(2017)
J Neurosci
, vol.37
, pp. 3568-3587
-
-
Freria, C.M.1
Hall, J.C.E.2
Wei, P.3
Guan, Z.4
McTigue, D.M.5
Popovich, P.G.6
-
33
-
-
34347270538
-
Proteolytic shedding of the macrophage scavenger receptor CD163 in multiple sclerosis
-
Fabriek BO, Møller HJ, Vloet RPM, van Winsen LM, Hanemaaijer R, Teunissen CE, et al. Proteolytic shedding of the macrophage scavenger receptor CD163 in multiple sclerosis. J Neuroimmunol (2007) 187:179-86. doi:10.1016/j.jneuroim.2007.04.016
-
(2007)
J Neuroimmunol
, vol.187
, pp. 179-186
-
-
Fabriek, B.O.1
Møller, H.J.2
Vloet, R.P.M.3
van Winsen, L.M.4
Hanemaaijer, R.5
Teunissen, C.E.6
-
34
-
-
84902313483
-
Soluble CD163 as a marker of macrophage activity in newly diagnosed patients with multiple sclerosis
-
Stilund M, Reuschlein A-K, Christensen T, Møller HJ, Rasmussen PV, Petersen T. Soluble CD163 as a marker of macrophage activity in newly diagnosed patients with multiple sclerosis. PLoS One (2014) 9:e98588. doi:10.1371/journal.pone.0098588
-
(2014)
PLoS One
, vol.9
-
-
Stilund, M.1
Reuschlein, A.-K.2
Christensen, T.3
Møller, H.J.4
Rasmussen, P.V.5
Petersen, T.6
-
35
-
-
84928905789
-
Biomarkers of inflammation and axonal degeneration/damage in patients with newly diagnosed multiple sclerosis: contributions of the soluble CD163 CSF/serum ratio to a biomarker panel
-
Stilund M, Gjelstrup MC, Petersen T, Møller HJ, Rasmussen PV, Christensen T. Biomarkers of inflammation and axonal degeneration/damage in patients with newly diagnosed multiple sclerosis: contributions of the soluble CD163 CSF/serum ratio to a biomarker panel. PLoS One (2015) 10:e0119681. doi:10.1371/journal.pone.0119681
-
(2015)
PLoS One
, vol.10
-
-
Stilund, M.1
Gjelstrup, M.C.2
Petersen, T.3
Møller, H.J.4
Rasmussen, P.V.5
Christensen, T.6
-
36
-
-
85027124182
-
CD169 is a marker for highly pathogenic phagocytes in multiple sclerosis
-
Bogie JF, Boelen E, Louagie E, Delputte P, Elewaut D, van Horssen J, et al. CD169 is a marker for highly pathogenic phagocytes in multiple sclerosis. Mult Scler (2017) 101:1352458517698759. doi:10.1177/1352458517698759
-
(2017)
Mult Scler
, vol.101
-
-
Bogie, J.F.1
Boelen, E.2
Louagie, E.3
Delputte, P.4
Elewaut, D.5
van Horssen, J.6
-
37
-
-
84955712112
-
TMEM119 marks a subset of microglia in the human brain
-
Satoh J-I, Kino Y, Asahina N, Takitani M, Miyoshi J, Ishida T, et al. TMEM119 marks a subset of microglia in the human brain. Neuropathology (2016) 36:39-49. doi:10.1111/neup.12235
-
(2016)
Neuropathology
, vol.36
, pp. 39-49
-
-
Satoh, J.-I.1
Kino, Y.2
Asahina, N.3
Takitani, M.4
Miyoshi, J.5
Ishida, T.6
-
38
-
-
85022328051
-
Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis
-
Zrzavy T, Hametner S, Wimmer I, Butovsky O, Weiner HL, Lassmann H. Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis. Brain (2017) 140:1900-13. doi:10.1093/brain/awx113
-
(2017)
Brain
, vol.140
, pp. 1900-1913
-
-
Zrzavy, T.1
Hametner, S.2
Wimmer, I.3
Butovsky, O.4
Weiner, H.L.5
Lassmann, H.6
-
39
-
-
84893745524
-
Identification of a unique TGF-β-dependent molecular and functional signature in microglia
-
Butovsky O, Jedrychowski MP, Moore CS, Cialic R, Lanser AJ, Gabriely G, et al. Identification of a unique TGF-β-dependent molecular and functional signature in microglia. Nat Neurosci (2014) 17:131-43. doi:10.1038/nn.3599
-
(2014)
Nat Neurosci
, vol.17
, pp. 131-143
-
-
Butovsky, O.1
Jedrychowski, M.P.2
Moore, C.S.3
Cialic, R.4
Lanser, A.J.5
Gabriely, G.6
-
40
-
-
33845951211
-
DAMPs, PAMPs and alarmins: all we need to know about danger
-
Bianchi ME. DAMPs, PAMPs and alarmins: all we need to know about danger. J Leukoc Biol (2007) 81:1-5. doi:10.1189/jlb.0306164
-
(2007)
J Leukoc Biol
, vol.81
, pp. 1-5
-
-
Bianchi, M.E.1
-
41
-
-
84897556094
-
The M1 and M2 paradigm of macrophage activation: time for reassessment
-
Martinez FO, Gordon S. The M1 and M2 paradigm of macrophage activation: time for reassessment. F1000Prime Rep (2014) 6:13. doi:10.12703/P6-13
-
(2014)
F1000Prime Rep
, vol.6
, pp. 13
-
-
Martinez, F.O.1
Gordon, S.2
-
42
-
-
84904394690
-
Macrophage activation and polarization: nomenclature and experimental guidelines
-
Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, et al. Macrophage activation and polarization: nomenclature and experimental guidelines. Immunity (2014) 41:14-20. doi:10.1016/j.immuni.2014.06.008
-
(2014)
Immunity
, vol.41
, pp. 14-20
-
-
Murray, P.J.1
Allen, J.E.2
Biswas, S.K.3
Fisher, E.A.4
Gilroy, D.W.5
Goerdt, S.6
-
43
-
-
84874499391
-
Polarization profiles of human M-CSF-generated macrophages and comparison of M1-markers in classically activated macrophages from GM-CSF and M-CSF origin
-
Jaguin M, Houlbert N, Fardel O, Lecureur V. Polarization profiles of human M-CSF-generated macrophages and comparison of M1-markers in classically activated macrophages from GM-CSF and M-CSF origin. Cell Immunol (2013) 281:51-61. doi:10.1016/j.cellimm.2013.01.010
-
(2013)
Cell Immunol
, vol.281
, pp. 51-61
-
-
Jaguin, M.1
Houlbert, N.2
Fardel, O.3
Lecureur, V.4
-
44
-
-
0031010661
-
Identification of nitric oxide synthase as a protective locus against tuberculosis
-
MacMicking JD, North RJ, LaCourse R, Mudgett JS, Shah SK, Nathan CF. Identification of nitric oxide synthase as a protective locus against tuberculosis. Proc Natl Acad Sci U S A (1997) 94:5243-8. doi:10.1073/pnas.94.10.5243
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 5243-5248
-
-
MacMicking, J.D.1
North, R.J.2
LaCourse, R.3
Mudgett, J.S.4
Shah, S.K.5
Nathan, C.F.6
-
45
-
-
84889632645
-
A critical role for suppressor of cytokine signalling 3 in promoting M1 macrophage activation and function in vitro and in vivo
-
Arnold CE, Whyte CS, Gordon P, Barker RN, Rees AJ, Wilson HM. A critical role for suppressor of cytokine signalling 3 in promoting M1 macrophage activation and function in vitro and in vivo. Immunology (2014) 141:96-110. doi:10.1111/imm.12173
-
(2014)
Immunology
, vol.141
, pp. 96-110
-
-
Arnold, C.E.1
Whyte, C.S.2
Gordon, P.3
Barker, R.N.4
Rees, A.J.5
Wilson, H.M.6
-
46
-
-
56749174940
-
Exploring the full spectrum of macrophage activation
-
Mosser DM, Edwards JP. Exploring the full spectrum of macrophage activation. Nat Rev Immunol (2008) 8:958-69. doi:10.1038/nri2448
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 958-969
-
-
Mosser, D.M.1
Edwards, J.P.2
-
47
-
-
84956883431
-
Novel markers to delineate murine M1 and M2 macrophages
-
Jablonski KA, Amici SA, Webb LM, de Dios Ruiz-Rosado J, Popovich PG, Partida-Sánchez S, et al. Novel markers to delineate murine M1 and M2 macrophages. PLoS One (2015) 10:e0145342. doi:10.1371/journal.pone.0145342
-
(2015)
PLoS One
, vol.10
-
-
Jablonski, K.A.1
Amici, S.A.2
Webb, L.M.3
de Dios Ruiz-Rosado, J.4
Popovich, P.G.5
Partida-Sánchez, S.6
-
48
-
-
84994035389
-
Identification of gene expression patterns crucially involved in experimental autoimmune encephalomyelitis and multiple sclerosis
-
Herrmann MM, Barth S, Greve B, Schumann KM, Bartels A, Weissert R. Identification of gene expression patterns crucially involved in experimental autoimmune encephalomyelitis and multiple sclerosis. Dis Model Mech (2016) 9:1211-20. doi:10.1242/dmm.025536
-
(2016)
Dis Model Mech
, vol.9
, pp. 1211-1220
-
-
Herrmann, M.M.1
Barth, S.2
Greve, B.3
Schumann, K.M.4
Bartels, A.5
Weissert, R.6
-
49
-
-
0035173647
-
Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo
-
Partida-Sánchez S, Cockayne DA, Monard S, Jacobson EL, Oppenheimer N, Garvy B, et al. Cyclic ADP-ribose production by CD38 regulates intracellular calcium release, extracellular calcium influx and chemotaxis in neutrophils and is required for bacterial clearance in vivo. Nat Med (2001) 7:1209-16. doi:10.1038/nm1101-1209
-
(2001)
Nat Med
, vol.7
, pp. 1209-1216
-
-
Partida-Sánchez, S.1
Cockayne, D.A.2
Monard, S.3
Jacobson, E.L.4
Oppenheimer, N.5
Garvy, B.6
-
50
-
-
85011691120
-
The nuclear receptor LXR limits bacterial infection of host macrophages through a mechanism that impacts cellular NAD metabolism
-
Matalonga J, Glaria E, Bresque M, Escande C, Carbó JM, Kiefer K, et al. The nuclear receptor LXR limits bacterial infection of host macrophages through a mechanism that impacts cellular NAD metabolism. Cell Rep (2017) 18:1241-55. doi:10.1016/j.celrep.2017.01.007
-
(2017)
Cell Rep
, vol.18
, pp. 1241-1255
-
-
Matalonga, J.1
Glaria, E.2
Bresque, M.3
Escande, C.4
Carbó, J.M.5
Kiefer, K.6
-
51
-
-
35548986304
-
Microglia: active sensor and versatile effector cells in the normal and pathologic brain
-
Hanisch U-K, Kettenmann H. Microglia: active sensor and versatile effector cells in the normal and pathologic brain. Nat Neurosci (2007) 10:1387-94. doi:10.1038/nn1997
-
(2007)
Nat Neurosci
, vol.10
, pp. 1387-1394
-
-
Hanisch, U.-K.1
Kettenmann, H.2
-
52
-
-
70449525135
-
Microglia in ALS: the good, the bad, and the resting
-
Henkel JS, Beers DR, Zhao W, Appel SH. Microglia in ALS: the good, the bad, and the resting. J Neuroimmune Pharmacol (2009) 4:389-98. doi:10.1007/s11481-009-9171-5
-
(2009)
J Neuroimmune Pharmacol
, vol.4
, pp. 389-398
-
-
Henkel, J.S.1
Beers, D.R.2
Zhao, W.3
Appel, S.H.4
-
53
-
-
77949901284
-
Assessing activation states in microglia
-
Colton CA, Wilcock DM. Assessing activation states in microglia. CNS Neurol Disord Drug Targets (2010) 9:174-91. doi:10.2174/187152710791012053
-
(2010)
CNS Neurol Disord Drug Targets
, vol.9
, pp. 174-191
-
-
Colton, C.A.1
Wilcock, D.M.2
-
54
-
-
84865973639
-
The classification of microglial activation phenotypes on neurodegeneration and regeneration in Alzheimer's disease brain
-
Varnum MM, Ikezu T. The classification of microglial activation phenotypes on neurodegeneration and regeneration in Alzheimer's disease brain. Arch Immunol Ther Exp (Warsz) (2012) 60:251-66. doi:10.1007/s00005-012-0181-2
-
(2012)
Arch Immunol Ther Exp (Warsz)
, vol.60
, pp. 251-266
-
-
Varnum, M.M.1
Ikezu, T.2
-
55
-
-
84872706357
-
Review: activation patterns of microglia and their identification in the human brain
-
Boche D, Perry VH, Nicoll JAR. Review: activation patterns of microglia and their identification in the human brain. Neuropathol Appl Neurobiol (2013) 39:3-18. doi:10.1111/nan.12011
-
(2013)
Neuropathol Appl Neurobiol
, vol.39
, pp. 3-18
-
-
Boche, D.1
Perry, V.H.2
Nicoll, J.A.R.3
-
56
-
-
47949092666
-
Dual role of CD38 in microglial activation and activation-induced cell death
-
Mayo L, Jacob-Hirsch J, Amariglio N, Rechavi G, Moutin M-J, Lund FE, et al. Dual role of CD38 in microglial activation and activation-induced cell death. J Immunol (2008) 181:92-103. doi:10.4049/jimmunol.181.1.92
-
(2008)
J Immunol
, vol.181
, pp. 92-103
-
-
Mayo, L.1
Jacob-Hirsch, J.2
Amariglio, N.3
Rechavi, G.4
Moutin, M.-J.5
Lund, F.E.6
-
57
-
-
84858072878
-
Comparison of polarization properties of human adult microglia and blood-derived macrophages
-
Durafourt BA, Moore CS, Zammit DA, Johnson TA, Zaguia F, Guiot M-C, et al. Comparison of polarization properties of human adult microglia and blood-derived macrophages. Glia (2012) 60:717-27. doi:10.1002/glia.22298
-
(2012)
Glia
, vol.60
, pp. 717-727
-
-
Durafourt, B.A.1
Moore, C.S.2
Zammit, D.A.3
Johnson, T.A.4
Zaguia, F.5
Guiot, M.-C.6
-
58
-
-
84901921079
-
Pro-resolving lipid mediators are leads for resolution physiology
-
Serhan CN. Pro-resolving lipid mediators are leads for resolution physiology. Nature (2014) 510:92-101. doi:10.1038/nature13479
-
(2014)
Nature
, vol.510
, pp. 92-101
-
-
Serhan, C.N.1
-
59
-
-
84978533746
-
Bioactive lipids as modulators of immunity, inflammation and emotions
-
Chiurchiù V, Maccarrone M. Bioactive lipids as modulators of immunity, inflammation and emotions. Curr Opin Pharmacol (2016) 29:54-62. doi:10.1016/j.coph.2016.06.005
-
(2016)
Curr Opin Pharmacol
, vol.29
, pp. 54-62
-
-
Chiurchiù, V.1
Maccarrone, M.2
-
60
-
-
85019188120
-
Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells
-
Bosurgi L, Cao YG, Cabeza-Cabrerizo M, Tucci A, Hughes LD, Kong Y, et al. Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells. Science (2017) 356:1072-6. doi:10.1126/science.aai8132
-
(2017)
Science
, vol.356
, pp. 1072-1076
-
-
Bosurgi, L.1
Cao, Y.G.2
Cabeza-Cabrerizo, M.3
Tucci, A.4
Hughes, L.D.5
Kong, Y.6
-
61
-
-
77954406421
-
Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas
-
Stella N. Cannabinoid and cannabinoid-like receptors in microglia, astrocytes, and astrocytomas. Glia (2010) 58:1017-30. doi:10.1002/glia.20983
-
(2010)
Glia
, vol.58
, pp. 1017-1030
-
-
Stella, N.1
-
62
-
-
84879629605
-
The novel 13S, 14S-epoxy-maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype
-
Dalli J, Zhu M, Vlasenko NA, Deng B, Haeggström JZ, Petasis NA, et al. The novel 13S, 14S-epoxy-maresin is converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A4 hydrolase (LTA4H), and shifts macrophage phenotype. FASEB J (2013) 27:2573-83. doi:10.1096/fj.13-227728
-
(2013)
FASEB J
, vol.27
, pp. 2573-2583
-
-
Dalli, J.1
Zhu, M.2
Vlasenko, N.A.3
Deng, B.4
Haeggström, J.Z.5
Petasis, N.A.6
-
63
-
-
80053445847
-
Inflammation and wound healing: the role of the macrophage
-
Koh TJ, DiPietro LA. Inflammation and wound healing: the role of the macrophage. Expert Rev Mol Med (2011) 13:e23. doi:10.1017/S1462399411001943
-
(2011)
Expert Rev Mol Med
, vol.13
-
-
Koh, T.J.1
DiPietro, L.A.2
-
64
-
-
7644231561
-
The chemokine system in diverse forms of macrophage activation and polarization
-
Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, Locati M. The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol (2004) 25:677-86. doi:10.1016/j.it.2004.09.015
-
(2004)
Trends Immunol
, vol.25
, pp. 677-686
-
-
Mantovani, A.1
Sica, A.2
Sozzani, S.3
Allavena, P.4
Vecchi, A.5
Locati, M.6
-
65
-
-
84879562515
-
Macrophage M1/M2 polarization dynamically adapts to changes in cytokine microenvironments in Cryptococcus neoformans infection
-
Davis MJ, Tsang TM, Qiu Y, Dayrit JK, Freij JB, Huffnagle GB, et al. Macrophage M1/M2 polarization dynamically adapts to changes in cytokine microenvironments in Cryptococcus neoformans infection. MBio (2013) 4:e00264-13. doi:10.1128/mBio.00264-13
-
(2013)
MBio
, vol.4
-
-
Davis, M.J.1
Tsang, T.M.2
Qiu, Y.3
Dayrit, J.K.4
Freij, J.B.5
Huffnagle, G.B.6
-
66
-
-
79251479406
-
Wound macrophages as key regulators of repair: origin, phenotype, and function
-
Brancato SK, Albina JE. Wound macrophages as key regulators of repair: origin, phenotype, and function. Am J Pathol (2011) 178:19-25. doi:10.1016/j.ajpath.2010.08.003
-
(2011)
Am J Pathol
, vol.178
, pp. 19-25
-
-
Brancato, S.K.1
Albina, J.E.2
-
67
-
-
77953268611
-
Alternative activation of macrophages: mechanism and functions
-
Gordon S, Martinez FO. Alternative activation of macrophages: mechanism and functions. Immunity (2010) 32:593-604. doi:10.1016/j.immuni.2010.05.007
-
(2010)
Immunity
, vol.32
, pp. 593-604
-
-
Gordon, S.1
Martinez, F.O.2
-
68
-
-
0036553909
-
Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages
-
Raes G, De Baetselier P, Noël W, Beschin A, Brombacher F, Hassanzadeh Gh G. Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages. J Leukoc Biol (2002) 71:597-602
-
(2002)
J Leukoc Biol
, vol.71
, pp. 597-602
-
-
Raes, G.1
De Baetselier, P.2
Noël, W.3
Beschin, A.4
Brombacher, F.5
Hassanzadeh Gh, G.6
-
69
-
-
39649120597
-
Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells
-
Duluc D, Delneste Y, Tan F, Moles M-P, Grimaud L, Lenoir J, et al. Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells. Blood (2007) 110:4319-30. doi:10.1182/blood-2007-02-072587
-
(2007)
Blood
, vol.110
, pp. 4319-4330
-
-
Duluc, D.1
Delneste, Y.2
Tan, F.3
Moles, M.-P.4
Grimaud, L.5
Lenoir, J.6
-
70
-
-
84930958641
-
Understanding the mysterious M2 macrophage through activation markers and effector mechanisms
-
Roszer T. Understanding the mysterious M2 macrophage through activation markers and effector mechanisms. Mediators Inflamm (2015) 2015:816460. doi:10.1155/2015/816460
-
(2015)
Mediators Inflamm
, vol.2015
-
-
Roszer, T.1
-
71
-
-
84855846598
-
Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology
-
Pello OM, De Pizzol M, Mirolo M, Soucek L, Zammataro L, Amabile A, et al. Role of c-MYC in alternative activation of human macrophages and tumor-associated macrophage biology. Blood (2012) 119:411-21. doi:10.1182/blood-2011-02-339911
-
(2012)
Blood
, vol.119
, pp. 411-421
-
-
Pello, O.M.1
De Pizzol, M.2
Mirolo, M.3
Soucek, L.4
Zammataro, L.5
Amabile, A.6
-
72
-
-
84934268208
-
Much more than M1 and M2 macrophages, there are also CD169(+) and TCR(+) macrophages
-
Chávez-Galán L, Olleros ML, Vesin D, Garcia I. Much more than M1 and M2 macrophages, there are also CD169(+) and TCR(+) macrophages. Front Immunol (2015) 6:263. doi:10.3389/fimmu.2015.00263
-
(2015)
Front Immunol
, vol.6
, pp. 263
-
-
Chávez-Galán, L.1
Olleros, M.L.2
Vesin, D.3
Garcia, I.4
-
73
-
-
84866554651
-
Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization and MerTK induction
-
Zizzo G, Hilliard BA, Monestier M, Cohen PL. Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization and MerTK induction. J Immunol (2012) 189:3508-20. doi:10.4049/jimmunol.1200662
-
(2012)
J Immunol
, vol.189
, pp. 3508-3520
-
-
Zizzo, G.1
Hilliard, B.A.2
Monestier, M.3
Cohen, P.L.4
-
74
-
-
84963812591
-
Flow cytometric analysis of myeloid cells in human blood, bronchoalveolar lavage, and lung tissues
-
Yu Y-RA, Hotten DF, Malakhau Y, Volker E, Ghio AJ, Noble PW, et al. Flow cytometric analysis of myeloid cells in human blood, bronchoalveolar lavage, and lung tissues. Am J Respir Cell Mol Biol (2016) 54:13-24. doi:10.1165/rcmb.2015-0146OC
-
(2016)
Am J Respir Cell Mol Biol
, vol.54
, pp. 13-24
-
-
Yu, Y.-R.A.1
Hotten, D.F.2
Malakhau, Y.3
Volker, E.4
Ghio, A.J.5
Noble, P.W.6
-
75
-
-
70350558453
-
Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord
-
Kigerl KA, Gensel JC, Ankeny DP, Alexander JK, Donnelly DJ, Popovich PG. Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord. J Neurosci (2009) 29:13435-44. doi:10.1523/JNEUROSCI.3257-09.2009
-
(2009)
J Neurosci
, vol.29
, pp. 13435-13444
-
-
Kigerl, K.A.1
Gensel, J.C.2
Ankeny, D.P.3
Alexander, J.K.4
Donnelly, D.J.5
Popovich, P.G.6
-
76
-
-
33645807860
-
The macrophage in MS: just a scavenger after all?. Pathology and pathogenesis of the acute MS lesion
-
Barnett MH, Henderson APD, Prineas JW. The macrophage in MS: just a scavenger after all? Pathology and pathogenesis of the acute MS lesion. Mult Scler (2006) 12:121-32. doi:10.1191/135248506ms1304rr
-
(2006)
Mult Scler
, vol.12
, pp. 121-132
-
-
Barnett, M.H.1
Henderson, A.P.D.2
Prineas, J.W.3
-
77
-
-
85031732784
-
The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases
-
Krasemann S, Madore C, Cialic R, Baufeld C, Calcagno N, Fatimy El R, et al. The TREM2-APOE pathway drives the transcriptional phenotype of dysfunctional microglia in neurodegenerative diseases. Immunity (2017) 47:566-81.e9. doi:10.1016/j.immuni.2017.08.008
-
(2017)
Immunity
, vol.47
, pp. 566-581
-
-
Krasemann, S.1
Madore, C.2
Cialic, R.3
Baufeld, C.4
Calcagno, N.5
Fatimy El, R.6
-
78
-
-
85016155890
-
Neurotoxic reactive astrocytes are induced by activated microglia
-
Liddelow SA, Guttenplan KA, Clarke LE, Bennett FC, Bohlen CJ, Schirmer L, et al. Neurotoxic reactive astrocytes are induced by activated microglia. Nature (2017) 541:481-7. doi:10.1038/nature21029
-
(2017)
Nature
, vol.541
, pp. 481-487
-
-
Liddelow, S.A.1
Guttenplan, K.A.2
Clarke, L.E.3
Bennett, F.C.4
Bohlen, C.J.5
Schirmer, L.6
-
79
-
-
85005822614
-
Myelin alters the inflammatory phenotype of macrophages by activating PPARs
-
Bogie JFJ, Jorissen W, Mailleux J, Nijland PG, Zelcer N, Vanmierlo T, et al. Myelin alters the inflammatory phenotype of macrophages by activating PPARs. Acta Neuropathol Commun (2013) 1:43. doi:10.1186/2051-5960-1-43
-
(2013)
Acta Neuropathol Commun
, vol.1
, pp. 43
-
-
Bogie, J.F.J.1
Jorissen, W.2
Mailleux, J.3
Nijland, P.G.4
Zelcer, N.5
Vanmierlo, T.6
-
80
-
-
84971654924
-
Multiple sclerosis: the resolving lesion revealed
-
Raine CS. Multiple sclerosis: the resolving lesion revealed. J Neuroimmunol (2017) 304:2-6. doi:10.1016/j.jneuroim.2016.05.021
-
(2017)
J Neuroimmunol
, vol.304
, pp. 2-6
-
-
Raine, C.S.1
-
81
-
-
84883454794
-
M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination
-
Miron VE, Boyd A, Zhao J-W, Yuen TJ, Ruckh JM, Shadrach JL, et al. M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination. Nat Neurosci (2013) 16:1211-8. doi:10.1038/nn.3469
-
(2013)
Nat Neurosci
, vol.16
, pp. 1211-1218
-
-
Miron, V.E.1
Boyd, A.2
Zhao, J.-W.3
Yuen, T.J.4
Ruckh, J.M.5
Shadrach, J.L.6
-
82
-
-
62849127355
-
Type II-activated macrophages suppress the development of experimental autoimmune encephalomyelitis
-
Tierney JB, Kharkrang M, La Flamme AC. Type II-activated macrophages suppress the development of experimental autoimmune encephalomyelitis. Immunol Cell Biol (2009) 87:235-40. doi:10.1038/icb.2008.99
-
(2009)
Immunol Cell Biol
, vol.87
, pp. 235-240
-
-
Tierney, J.B.1
Kharkrang, M.2
La Flamme, A.C.3
-
83
-
-
84864002777
-
IL-33 attenuates EAE by suppressing IL-17 and IFN-?. production and inducing alternatively activated macrophages
-
Jiang H-R, Milovanovic M, Allan D, Niedbala W, Besnard A-G, Fukada SY, et al. IL-33 attenuates EAE by suppressing IL-17 and IFN-? production and inducing alternatively activated macrophages. Eur J Immunol (2012) 42:1804-14. doi:10.1002/eji.201141947
-
(2012)
Eur J Immunol
, vol.42
, pp. 1804-1814
-
-
Jiang, H.-R.1
Milovanovic, M.2
Allan, D.3
Niedbala, W.4
Besnard, A.-G.5
Fukada, S.Y.6
-
84
-
-
85009858788
-
Helminth-induced Ly6C(hi) monocyte-derived alternatively activated macrophages suppress experimental autoimmune encephalomyelitis
-
Terrazas C, de Dios Ruiz-Rosado J, Amici SA, Jablonski KA, Martinez-Saucedo D, Webb LM, et al. Helminth-induced Ly6C(hi) monocyte-derived alternatively activated macrophages suppress experimental autoimmune encephalomyelitis. Sci Rep (2017) 7:40814. doi:10.1038/srep40814
-
(2017)
Sci Rep
, vol.7
, pp. 40814
-
-
Terrazas, C.1
de Dios Ruiz-Rosado, J.2
Amici, S.A.3
Jablonski, K.A.4
Martinez-Saucedo, D.5
Webb, L.M.6
-
85
-
-
85014630540
-
Akt signaling pathway in macrophage activation and M1/M2 polarization
-
Vergadi E, Ieronymaki E, Lyroni K, Vaporidi K, Tsatsanis C. Akt signaling pathway in macrophage activation and M1/M2 polarization. J Immunol (2017) 198:1006-14. doi:10.4049/jimmunol.1601515
-
(2017)
J Immunol
, vol.198
, pp. 1006-1014
-
-
Vergadi, E.1
Ieronymaki, E.2
Lyroni, K.3
Vaporidi, K.4
Tsatsanis, C.5
-
86
-
-
79957553362
-
Cot/tpl2 activity is required for TLR-induced activation of the Akt p70 S6k pathway in macrophages: implications for NO synthase 2 expression
-
López-Peláez M, Soria-Castro I, Boscá L, Fernández M, Alemany S. Cot/tpl2 activity is required for TLR-induced activation of the Akt p70 S6k pathway in macrophages: implications for NO synthase 2 expression. Eur J Immunol (2011) 41:1733-41. doi:10.1002/eji.201041101
-
(2011)
Eur J Immunol
, vol.41
, pp. 1733-1741
-
-
López-Peláez, M.1
Soria-Castro, I.2
Boscá, L.3
Fernández, M.4
Alemany, S.5
-
87
-
-
44849113635
-
Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages
-
Luyendyk JP, Schabbauer GA, Tencati M, Holscher T, Pawlinski R, Mackman N. Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages. J Immunol (2008) 180:4218-26. doi:10.4049/jimmunol.180.6.4218
-
(2008)
J Immunol
, vol.180
, pp. 4218-4226
-
-
Luyendyk, J.P.1
Schabbauer, G.A.2
Tencati, M.3
Holscher, T.4
Pawlinski, R.5
Mackman, N.6
-
88
-
-
0033563141
-
Negative regulation by phosphatidylinositol 3-kinase of inducible nitric oxide synthase expression in macrophages
-
Díaz-Guerra MJ, Castrillo A, Martín-Sanz P, Boscá L. Negative regulation by phosphatidylinositol 3-kinase of inducible nitric oxide synthase expression in macrophages. J Immunol (1999) 162:6184-90
-
(1999)
J Immunol
, vol.162
, pp. 6184-6190
-
-
Díaz-Guerra, M.J.1
Castrillo, A.2
Martín-Sanz, P.3
Boscá, L.4
-
89
-
-
34250803183
-
Role of phosphatidylinositol-3 kinase in transcriptional regulation of TLR-induced IL-12 and IL-10 by Fc gamma receptor ligation in murine macrophages
-
Polumuri SK, Toshchakov VY, Vogel SN. Role of phosphatidylinositol-3 kinase in transcriptional regulation of TLR-induced IL-12 and IL-10 by Fc gamma receptor ligation in murine macrophages. J Immunol (2007) 179:236-46. doi:10.4049/jimmunol.179.1.236
-
(2007)
J Immunol
, vol.179
, pp. 236-246
-
-
Polumuri, S.K.1
Toshchakov, V.Y.2
Vogel, S.N.3
-
90
-
-
33644506745
-
Lipopolysaccharide-induced production of interleukin-10 is promoted by the serine/threonine kinase Akt
-
Pengal RA, Ganesan LP, Wei G, Fang H, Ostrowski MC, Tridandapani S. Lipopolysaccharide-induced production of interleukin-10 is promoted by the serine/threonine kinase Akt. Mol Immunol (2006) 43:1557-64. doi:10.1016/j.molimm.2005.09.022
-
(2006)
Mol Immunol
, vol.43
, pp. 1557-1564
-
-
Pengal, R.A.1
Ganesan, L.P.2
Wei, G.3
Fang, H.4
Ostrowski, M.C.5
Tridandapani, S.6
-
91
-
-
84862187485
-
Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization
-
Arranz A, Doxaki C, Vergadi E, la Torre de YM, Vaporidi K, Lagoudaki ED, et al. Akt1 and Akt2 protein kinases differentially contribute to macrophage polarization. Proc Natl Acad Sci U S A (2012) 109:9517-22. doi:10.1073/pnas.1119038109
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 9517-9522
-
-
Arranz, A.1
Doxaki, C.2
Vergadi, E.3
la Torre de, Y.M.4
Vaporidi, K.5
Lagoudaki, E.D.6
-
92
-
-
46149106818
-
The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma
-
Guillermet-Guibert J, Bjorklof K, Salpekar A, Gonella C, Ramadani F, Bilancio A, et al. The p110beta isoform of phosphoinositide 3-kinase signals downstream of G protein-coupled receptors and is functionally redundant with p110gamma. Proc Natl Acad Sci U S A (2008) 105:8292-7. doi:10.1073/pnas.0707761105
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 8292-8297
-
-
Guillermet-Guibert, J.1
Bjorklof, K.2
Salpekar, A.3
Gonella, C.4
Ramadani, F.5
Bilancio, A.6
-
93
-
-
84891079308
-
Akt2 deficiency protects from acute lung injury via alternative macrophage activation and miR-146a induction in mice
-
Vergadi E, Vaporidi K, Theodorakis EE, Doxaki C, Lagoudaki E, Ieronymaki E, et al. Akt2 deficiency protects from acute lung injury via alternative macrophage activation and miR-146a induction in mice. J Immunol (2014) 192:394-406. doi:10.4049/jimmunol.1300959
-
(2014)
J Immunol
, vol.192
, pp. 394-406
-
-
Vergadi, E.1
Vaporidi, K.2
Theodorakis, E.E.3
Doxaki, C.4
Lagoudaki, E.5
Ieronymaki, E.6
-
94
-
-
36749030024
-
Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1
-
Kuijl C, Savage NDL, Marsman M, Tuin AW, Janssen L, Egan DA, et al. Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1. Nature (2007) 450:725-30. doi:10.1038/nature06345
-
(2007)
Nature
, vol.450
, pp. 725-730
-
-
Kuijl, C.1
Savage, N.D.L.2
Marsman, M.3
Tuin, A.W.4
Janssen, L.5
Egan, D.A.6
-
95
-
-
68649091506
-
The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs
-
Androulidaki A, Iliopoulos D, Arranz A, Doxaki C, Schworer S, Zacharioudaki V, et al. The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs. Immunity (2009) 31:220-31. doi:10.1016/j.immuni.2009.06.024
-
(2009)
Immunity
, vol.31
, pp. 220-231
-
-
Androulidaki, A.1
Iliopoulos, D.2
Arranz, A.3
Doxaki, C.4
Schworer, S.5
Zacharioudaki, V.6
-
96
-
-
84979684888
-
Control of the inflammatory macrophage transcriptional signature by miR-155
-
Jablonski KA, Gaudet AD, Amici SA, Popovich PG, Guerau-de-Arellano M. Control of the inflammatory macrophage transcriptional signature by miR-155. PLoS One (2016) 11:e0159724. doi:10.1371/journal.pone.0159724
-
(2016)
PLoS One
, vol.11
-
-
Jablonski, K.A.1
Gaudet, A.D.2
Amici, S.A.3
Popovich, P.G.4
Guerau-de-Arellano, M.5
-
97
-
-
84867420120
-
Re-polarization of tumor-associated macrophages to pro-inflammatory M1 macrophages by microRNA-155
-
Cai X, Yin Y, Li N, Zhu D, Zhang J, Zhang C-Y, et al. Re-polarization of tumor-associated macrophages to pro-inflammatory M1 macrophages by microRNA-155. J Mol Cell Biol (2012) 4:341-3. doi:10.1093/jmcb/mjs044
-
(2012)
J Mol Cell Biol
, vol.4
, pp. 341-343
-
-
Cai, X.1
Yin, Y.2
Li, N.3
Zhu, D.4
Zhang, J.5
Zhang, C.-Y.6
-
98
-
-
70350445698
-
A CREB-C/EBPbeta cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair
-
Ruffell D, Mourkioti F, Gambardella A, Kirstetter P, Lopez RG, Rosenthal N, et al. A CREB-C/EBPbeta cascade induces M2 macrophage-specific gene expression and promotes muscle injury repair. Proc Natl Acad Sci U S A (2009) 106:17475-80. doi:10.1073/pnas.0908641106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 17475-17480
-
-
Ruffell, D.1
Mourkioti, F.2
Gambardella, A.3
Kirstetter, P.4
Lopez, R.G.5
Rosenthal, N.6
-
99
-
-
84855387052
-
Myeloid cell IL-10 production in response to Leishmania involves inactivation of glycogen synthase kinase-3β downstream of phosphatidylinositol-3 kinase
-
Nandan D, Camargo de Oliveira C, Moeenrezakhanlou A, Lopez M, Silverman JM, Subek J, et al. Myeloid cell IL-10 production in response to Leishmania involves inactivation of glycogen synthase kinase-3β downstream of phosphatidylinositol-3 kinase. J Immunol (2012) 188:367-78. doi:10.4049/jimmunol.1100076
-
(2012)
J Immunol
, vol.188
, pp. 367-378
-
-
Nandan, D.1
Camargo de Oliveira, C.2
Moeenrezakhanlou, A.3
Lopez, M.4
Silverman, J.M.5
Subek, J.6
-
100
-
-
84936764355
-
Attenuation of cardiac dysfunction in polymicrobial sepsis by microRNA-146a is mediated via targeting of IRAK1 and TRAF6 expression
-
Gao M, Wang X, Zhang X, Ha T, Ma H, Liu L, et al. Attenuation of cardiac dysfunction in polymicrobial sepsis by microRNA-146a is mediated via targeting of IRAK1 and TRAF6 expression. J Immunol (2015) 195:672-82. doi:10.4049/jimmunol.1403155
-
(2015)
J Immunol
, vol.195
, pp. 672-682
-
-
Gao, M.1
Wang, X.2
Zhang, X.3
Ha, T.4
Ma, H.5
Liu, L.6
-
101
-
-
84941174437
-
miR-146a-5p antagonized AGEs-and P.g-LPS-induced ABCA1 and ABCG1 dysregulation in macrophages via IRAK-1 downregulation
-
Li X, Ji Z, Li S, Sun Y-N, Liu J, Liu Y, et al. miR-146a-5p antagonized AGEs-and P.g-LPS-induced ABCA1 and ABCG1 dysregulation in macrophages via IRAK-1 downregulation. Inflammation (2015) 38:1761-8. doi:10.1007/s10753-015-0153-x
-
(2015)
Inflammation
, vol.38
, pp. 1761-1768
-
-
Li, X.1
Ji, Z.2
Li, S.3
Sun, Y.-N.4
Liu, J.5
Liu, Y.6
-
102
-
-
85001728410
-
MicroR-146 blocks the activation of M1 macrophage by targeting signal transducer and activator of transcription 1 in hepatic schistosomiasis
-
He X, Tang R, Sun Y, Wang Y-G, Zhen K-Y, Zhang D-M, et al. MicroR-146 blocks the activation of M1 macrophage by targeting signal transducer and activator of transcription 1 in hepatic schistosomiasis. EBioMedicine (2016) 13:339-47. doi:10.1016/j.ebiom.2016.10.024
-
(2016)
EBioMedicine
, vol.13
, pp. 339-347
-
-
He, X.1
Tang, R.2
Sun, Y.3
Wang, Y.-G.4
Zhen, K.-Y.5
Zhang, D.-M.6
-
103
-
-
84928714689
-
miR-146a suppresses cellular immune response during Japanese encephalitis virus JaOArS982 strain infection in human microglial cells
-
Sharma N, Verma R, Kumawat KL, Basu A, Singh SK. miR-146a suppresses cellular immune response during Japanese encephalitis virus JaOArS982 strain infection in human microglial cells. J Neuroinflammation (2015) 12:30. doi:10.1186/s12974-015-0249-0
-
(2015)
J Neuroinflammation
, vol.12
, pp. 30
-
-
Sharma, N.1
Verma, R.2
Kumawat, K.L.3
Basu, A.4
Singh, S.K.5
-
104
-
-
84873560332
-
Suppression of inflammatory responses during myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis is regulated by AKT3 signaling
-
Tsiperson V, Gruber RC, Goldberg MF, Jordan A, Weinger JG, Macian F, et al. Suppression of inflammatory responses during myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis is regulated by AKT3 signaling. J Immunol (2013) 190:1528-39. doi:10.4049/jimmunol.1201387
-
(2013)
J Immunol
, vol.190
, pp. 1528-1539
-
-
Tsiperson, V.1
Gruber, R.C.2
Goldberg, M.F.3
Jordan, A.4
Weinger, J.G.5
Macian, F.6
-
105
-
-
84936980783
-
Tsc1 is a critical regulator of macrophage survival and function
-
Fang C, Yu J, Luo Y, Chen S, Wang W, Zhao C, et al. Tsc1 is a critical regulator of macrophage survival and function. Cell Physiol Biochem (2015) 36:1406-18. doi:10.1159/000430306
-
(2015)
Cell Physiol Biochem
, vol.36
, pp. 1406-1418
-
-
Fang, C.1
Yu, J.2
Luo, Y.3
Chen, S.4
Wang, W.5
Zhao, C.6
-
106
-
-
54949109311
-
The TSC-mTOR signaling pathway regulates the innate inflammatory response
-
Weichhart T, Costantino G, Poglitsch M, Rosner M, Zeyda M, Stuhlmeier KM, et al. The TSC-mTOR signaling pathway regulates the innate inflammatory response. Immunity (2008) 29:565-77. doi:10.1016/j.immuni.2008.08.012
-
(2008)
Immunity
, vol.29
, pp. 565-577
-
-
Weichhart, T.1
Costantino, G.2
Poglitsch, M.3
Rosner, M.4
Zeyda, M.5
Stuhlmeier, K.M.6
-
107
-
-
84455161606
-
Mammalian target of rapamycin complex 2 (mTORC2) negatively regulates toll-like receptor 4-mediated inflammatory response via FoxO1
-
Brown J, Wang H, Suttles J, Graves DT, Martin M. Mammalian target of rapamycin complex 2 (mTORC2) negatively regulates toll-like receptor 4-mediated inflammatory response via FoxO1. J Biol Chem (2011) 286:44295-305. doi:10.1074/jbc.M111.258053
-
(2011)
J Biol Chem
, vol.286
, pp. 44295-44305
-
-
Brown, J.1
Wang, H.2
Suttles, J.3
Graves, D.T.4
Martin, M.5
-
108
-
-
84899670376
-
Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide
-
Festuccia WT, Pouliot P, Bakan I, Sabatini DM, Laplante M. Myeloid-specific Rictor deletion induces M1 macrophage polarization and potentiates in vivo pro-inflammatory response to lipopolysaccharide. PLoS One (2014) 9:e95432. doi:10.1371/journal.pone.0095432
-
(2014)
PLoS One
, vol.9
-
-
Festuccia, W.T.1
Pouliot, P.2
Bakan, I.3
Sabatini, D.M.4
Laplante, M.5
-
109
-
-
84889249320
-
The TSC-mTOR pathway regulates macrophage polarization
-
Byles V, Covarrubias AJ, Ben-Sahra I, Lamming DW, Sabatini DM, Manning BD, et al. The TSC-mTOR pathway regulates macrophage polarization. Nat Commun (2013) 4:2834. doi:10.1038/ncomms3834
-
(2013)
Nat Commun
, vol.4
, pp. 2834
-
-
Byles, V.1
Covarrubias, A.J.2
Ben-Sahra, I.3
Lamming, D.W.4
Sabatini, D.M.5
Manning, B.D.6
-
110
-
-
84961281785
-
Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation
-
Covarrubias AJ, Aksoylar HI, Yu J, Snyder NW, Worth AJ, Iyer SS, et al. Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation. Elife (2016) 5:R106. doi:10.7554/eLife.11612
-
(2016)
Elife
, vol.5
-
-
Covarrubias, A.J.1
Aksoylar, H.I.2
Yu, J.3
Snyder, N.W.4
Worth, A.J.5
Iyer, S.S.6
-
111
-
-
84860333507
-
The role of tuberous sclerosis complex 1 in regulating innate immunity
-
Pan H, O'Brien TF, Zhang P, Zhong X-P. The role of tuberous sclerosis complex 1 in regulating innate immunity. J Immunol (2012) 188:3658-66. doi:10.4049/jimmunol.1102187
-
(2012)
J Immunol
, vol.188
, pp. 3658-3666
-
-
Pan, H.1
O'Brien, T.F.2
Zhang, P.3
Zhong, X.-P.4
-
112
-
-
84883761914
-
Rapamycin unbalances the polarization of human macrophages to M1
-
Mercalli A, Calavita I, Dugnani E, Citro A, Cantarelli E, Nano R, et al. Rapamycin unbalances the polarization of human macrophages to M1. Immunology (2013) 140:179-90. doi:10.1111/imm.12126
-
(2013)
Immunology
, vol.140
, pp. 179-190
-
-
Mercalli, A.1
Calavita, I.2
Dugnani, E.3
Citro, A.4
Cantarelli, E.5
Nano, R.6
-
115
-
-
34250313956
-
Delta-like 4 induces notch signaling in macrophages: implications for inflammation
-
Fung E, Tang S-MT, Canner JP, Morishige K, Arboleda-Velasquez JF, Cardoso AA, et al. Delta-like 4 induces notch signaling in macrophages: implications for inflammation. Circulation (2007) 115:2948-56. doi:10.1161/CIRCULATIONAHA.106.675462
-
(2007)
Circulation
, vol.115
, pp. 2948-2956
-
-
Fung, E.1
Tang, S.-M.T.2
Canner, J.P.3
Morishige, K.4
Arboleda-Velasquez, J.F.5
Cardoso, A.A.6
-
116
-
-
70349249979
-
Notch1 upregulates LPS-induced macrophage activation by increasing NF-kappaB activity
-
Monsalve E, Ruiz-García A, Baladrón V, Ruiz-Hidalgo MJ, Sánchez-Solana B, Rivero S, et al. Notch1 upregulates LPS-induced macrophage activation by increasing NF-kappaB activity. Eur J Immunol (2009) 39:2556-70. doi:10.1002/eji.200838722
-
(2009)
Eur J Immunol
, vol.39
, pp. 2556-2570
-
-
Monsalve, E.1
Ruiz-García, A.2
Baladrón, V.3
Ruiz-Hidalgo, M.J.4
Sánchez-Solana, B.5
Rivero, S.6
-
117
-
-
84862591151
-
Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization
-
Xu H, Zhu J, Smith S, Foldi J, Zhao B, Chung AY, et al. Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization. Nat Immunol (2012) 13:642-50. doi:10.1038/ni.2304
-
(2012)
Nat Immunol
, vol.13
, pp. 642-650
-
-
Xu, H.1
Zhu, J.2
Smith, S.3
Foldi, J.4
Zhao, B.5
Chung, A.Y.6
-
118
-
-
38349075227
-
Notch signaling is activated by TLR stimulation and regulates macrophage functions
-
Palaga T, Buranaruk C, Rengpipat S, Fauq AH, Golde TE, Kaufmann SHE, et al. Notch signaling is activated by TLR stimulation and regulates macrophage functions. Eur J Immunol (2008) 38:174-83. doi:10.1002/eji.200636999
-
(2008)
Eur J Immunol
, vol.38
, pp. 174-183
-
-
Palaga, T.1
Buranaruk, C.2
Rengpipat, S.3
Fauq, A.H.4
Golde, T.E.5
Kaufmann, S.H.E.6
-
119
-
-
33645976866
-
Notch-1 up-regulation and signaling following macrophage activation modulates gene expression patterns known to affect antigen-presenting capacity and cytotoxic activity
-
Monsalve E, Pérez MA, Rubio A, Ruiz-Hidalgo MJ, Baladrón V, García-Ramírez JJ, et al. Notch-1 up-regulation and signaling following macrophage activation modulates gene expression patterns known to affect antigen-presenting capacity and cytotoxic activity. J Immunol (2006) 176:5362-73. doi:10.4049/jimmunol.176.9.5362
-
(2006)
J Immunol
, vol.176
, pp. 5362-5373
-
-
Monsalve, E.1
Pérez, M.A.2
Rubio, A.3
Ruiz-Hidalgo, M.J.4
Baladrón, V.5
García-Ramírez, J.J.6
-
120
-
-
84861221733
-
Involvement of Notch signaling pathway in regulating IL-12 expression via c-Rel in activated macrophages
-
Boonyatecha N, Sangphech N, Wongchana W, Kueanjinda P, Palaga T. Involvement of Notch signaling pathway in regulating IL-12 expression via c-Rel in activated macrophages. Mol Immunol (2012) 51:255-62. doi:10.1016/j.molimm.2012.03.017
-
(2012)
Mol Immunol
, vol.51
, pp. 255-262
-
-
Boonyatecha, N.1
Sangphech, N.2
Wongchana, W.3
Kueanjinda, P.4
Palaga, T.5
-
121
-
-
84865135512
-
miR-96 downregulates REV1 and RAD51 to promote cellular sensitivity to cisplatin and PARP inhibition
-
Wang Y, Huang J-W, Calses P, Kemp CJ, Taniguchi T. miR-96 downregulates REV1 and RAD51 to promote cellular sensitivity to cisplatin and PARP inhibition. Cancer Res (2012) 72:4037-46. doi:10.1158/0008-5472.CAN-12-0103
-
(2012)
Cancer Res
, vol.72
, pp. 4037-4046
-
-
Wang, Y.1
Huang, J.-W.2
Calses, P.3
Kemp, C.J.4
Taniguchi, T.5
-
122
-
-
77958128428
-
Notch1 deficiency results in decreased inflammation during wound healing and regulates vascular endothelial growth factor receptor-1 and inflammatory cytokine expression in macrophages
-
Outtz HH, Wu JK, Wang X, Kitajewski J. Notch1 deficiency results in decreased inflammation during wound healing and regulates vascular endothelial growth factor receptor-1 and inflammatory cytokine expression in macrophages. J Immunol (2010) 185:4363-73. doi:10.4049/jimmunol.1000720
-
(2010)
J Immunol
, vol.185
, pp. 4363-4373
-
-
Outtz, H.H.1
Wu, J.K.2
Wang, X.3
Kitajewski, J.4
-
123
-
-
84913554530
-
Regulation of Notch 1 signaling in THP-1 cells enhances M2 macrophage differentiation
-
Singla RD, Wang J, Singla DK. Regulation of Notch 1 signaling in THP-1 cells enhances M2 macrophage differentiation. Am J Physiol Heart Circ Physiol (2014) 307:H1634-42. doi:10.1152/ajpheart.00896.2013
-
(2014)
Am J Physiol Heart Circ Physiol
, vol.307
, pp. H1634-H1642
-
-
Singla, R.D.1
Wang, J.2
Singla, D.K.3
-
124
-
-
84926308649
-
NOTCH reprograms mitochondrial metabolism for proinflammatory macrophage activation
-
Xu J, Chi F, Guo T, Punj V, Lee WNP, French SW, et al. NOTCH reprograms mitochondrial metabolism for proinflammatory macrophage activation. J Clin Invest (2015) 125:1579-90. doi:10.1172/JCI76468
-
(2015)
J Clin Invest
, vol.125
, pp. 1579-1590
-
-
Xu, J.1
Chi, F.2
Guo, T.3
Punj, V.4
Lee, W.N.P.5
French, S.W.6
-
125
-
-
77955496321
-
Nuclear factor-?B/p65 responds to changes in the Notch signaling pathway in murine BV-2 cells and in amoeboid microglia in postnatal rats treated with the ?-secretase complex blocker DAPT
-
Cao Q, Li P, Lu J, Dheen ST, Kaur C, Ling E-A. Nuclear factor-?B/p65 responds to changes in the Notch signaling pathway in murine BV-2 cells and in amoeboid microglia in postnatal rats treated with the ?-secretase complex blocker DAPT. J Neurosci Res (2010) 88:2701-14. doi:10.1002/jnr.22429
-
(2010)
J Neurosci Res
, vol.88
, pp. 2701-2714
-
-
Cao, Q.1
Li, P.2
Lu, J.3
Dheen, S.T.4
Kaur, C.5
Ling, E.-A.6
-
126
-
-
80052424570
-
Notch activation enhances the microglia-mediated inflammatory response associated with focal cerebral ischemia
-
Wei Z, Chigurupati S, Arumugam TV, Jo D-G, Li H, Chan SL. Notch activation enhances the microglia-mediated inflammatory response associated with focal cerebral ischemia. Stroke (2011) 42:2589-94. doi:10.1161/STROKEAHA.111.614834
-
(2011)
Stroke
, vol.42
, pp. 2589-2594
-
-
Wei, Z.1
Chigurupati, S.2
Arumugam, T.V.3
Jo, D.-G.4
Li, H.5
Chan, S.L.6
-
127
-
-
84892394146
-
Notch-1 signaling regulates microglia activation via NF-?B pathway after hypoxic exposure in vivo and in vitro
-
Yao L, Kan EM, Kaur C, Dheen ST, Hao A, Lu J, et al. Notch-1 signaling regulates microglia activation via NF-?B pathway after hypoxic exposure in vivo and in vitro. PLoS One (2013) 8:e78439. doi:10.1371/journal.pone.0078439
-
(2013)
PLoS One
, vol.8
-
-
Yao, L.1
Kan, E.M.2
Kaur, C.3
Dheen, S.T.4
Hao, A.5
Lu, J.6
-
128
-
-
84948767328
-
Impact of Notch1 deletion in macrophages on proinflammatory cytokine production and the outcome of experimental autoimmune encephalomyelitis
-
Wongchana W, Lawlor RG, Osborne BA, Palaga T. Impact of Notch1 deletion in macrophages on proinflammatory cytokine production and the outcome of experimental autoimmune encephalomyelitis. J Immunol (2015) 195:5337-46. doi:10.4049/jimmunol.1401770
-
(2015)
J Immunol
, vol.195
, pp. 5337-5346
-
-
Wongchana, W.1
Lawlor, R.G.2
Osborne, B.A.3
Palaga, T.4
-
129
-
-
84863116579
-
Hedgehog and Notch signaling regulate self-renewal of undifferentiated pleomorphic sarcomas
-
Wang CYY, Wei Q, Han I, Sato S, Ghanbari-Azarnier R, Whetstone H, et al. Hedgehog and Notch signaling regulate self-renewal of undifferentiated pleomorphic sarcomas. Cancer Res (2012) 72:1013-22. doi:10.1158/0008-5472.CAN-11-2531
-
(2012)
Cancer Res
, vol.72
, pp. 1013-1022
-
-
Wang, C.Y.Y.1
Wei, Q.2
Han, I.3
Sato, S.4
Ghanbari-Azarnier, R.5
Whetstone, H.6
-
130
-
-
33751533892
-
International union of pharmacology LXI. Peroxisome proliferator-activated receptors
-
Michalik L, Auwerx J, Berger JP, Chatterjee VK, Glass CK, Gonzalez FJ, et al. International union of pharmacology. LXI. Peroxisome proliferator-activated receptors. Pharmacol Rev (2006) 58:726-41. doi:10.1124/pr.58.4.5
-
(2006)
Pharmacol Rev
, vol.58
, pp. 726-741
-
-
Michalik, L.1
Auwerx, J.2
Berger, J.P.3
Chatterjee, V.K.4
Glass, C.K.5
Gonzalez, F.J.6
-
131
-
-
0033793133
-
Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation
-
Chinetti G, Fruchart JC, Staels B. Peroxisome proliferator-activated receptors (PPARs): nuclear receptors at the crossroads between lipid metabolism and inflammation. Inflamm Res (2000) 49:497-505. doi:10.1007/s000110050622
-
(2000)
Inflamm Res
, vol.49
, pp. 497-505
-
-
Chinetti, G.1
Fruchart, J.C.2
Staels, B.3
-
132
-
-
0033595261
-
Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase
-
Huang JT, Welch JS, Ricote M, Binder CJ, Willson TM, Kelly C, et al. Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase. Nature (1999) 400:378-82. doi:10.1038/22572
-
(1999)
Nature
, vol.400
, pp. 378-382
-
-
Huang, J.T.1
Welch, J.S.2
Ricote, M.3
Binder, C.J.4
Willson, T.M.5
Kelly, C.6
-
133
-
-
0141455974
-
PPARgamma promotes mannose receptor gene expression in murine macrophages and contributes to the induction of this receptor by IL-13
-
Coste A, Dubourdeau M, Linas MD, Cassaing S, Lepert J-C, Balard P, et al. PPARgamma promotes mannose receptor gene expression in murine macrophages and contributes to the induction of this receptor by IL-13. Immunity (2003) 19:329-39. doi:10.1016/S1074-7613(03)00229-2
-
(2003)
Immunity
, vol.19
, pp. 329-339
-
-
Coste, A.1
Dubourdeau, M.2
Linas, M.D.3
Cassaing, S.4
Lepert, J.-C.5
Balard, P.6
-
134
-
-
36049034344
-
Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms
-
Straus DS, Glass CK. Anti-inflammatory actions of PPAR ligands: new insights on cellular and molecular mechanisms. Trends Immunol (2007) 28:551-8. doi:10.1016/j.it.2007.09.003
-
(2007)
Trends Immunol
, vol.28
, pp. 551-558
-
-
Straus, D.S.1
Glass, C.K.2
-
135
-
-
11144357288
-
Peroxisome proliferator-activated receptor alpha agonists as therapy for autoimmune disease
-
Lovett-Racke AE, Hussain RZ, Northrop S, Choy J, Rocchini A, Matthes L, et al. Peroxisome proliferator-activated receptor alpha agonists as therapy for autoimmune disease. J Immunol (2004) 172:5790-8. doi:10.4049/jimmunol.172.9.5790
-
(2004)
J Immunol
, vol.172
, pp. 5790-5798
-
-
Lovett-Racke, A.E.1
Hussain, R.Z.2
Northrop, S.3
Choy, J.4
Rocchini, A.5
Matthes, L.6
-
136
-
-
33847161302
-
Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity
-
Dunn SE, Ousman SS, Sobel RA, Zuniga L, Baranzini SE, Youssef S, et al. Peroxisome proliferator-activated receptor (PPAR)alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity. J Exp Med (2007) 204:321-30. doi:10.1084/jem.20061839
-
(2007)
J Exp Med
, vol.204
, pp. 321-330
-
-
Dunn, S.E.1
Ousman, S.S.2
Sobel, R.A.3
Zuniga, L.4
Baranzini, S.E.5
Youssef, S.6
-
137
-
-
84975109883
-
Homeostatic PPARa signaling limits inflammatory responses to commensal microbiota in the intestine
-
Manoharan I, Suryawanshi A, Hong Y, Ranganathan P, Shanmugam A, Ahmad S, et al. Homeostatic PPARa signaling limits inflammatory responses to commensal microbiota in the intestine. J Immunol (2016) 196:4739-49. doi:10.4049/jimmunol.1501489
-
(2016)
J Immunol
, vol.196
, pp. 4739-4749
-
-
Manoharan, I.1
Suryawanshi, A.2
Hong, Y.3
Ranganathan, P.4
Shanmugam, A.5
Ahmad, S.6
-
138
-
-
34547492488
-
PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties
-
Bouhlel MA, Derudas B, Rigamonti E, Dièvart R, Brozek J, Haulon S, et al. PPARgamma activation primes human monocytes into alternative M2 macrophages with anti-inflammatory properties. Cell Metab (2007) 6:137-43. doi:10.1016/j.cmet.2007.06.010
-
(2007)
Cell Metab
, vol.6
, pp. 137-143
-
-
Bouhlel, M.A.1
Derudas, B.2
Rigamonti, E.3
Dièvart, R.4
Brozek, J.5
Haulon, S.6
-
139
-
-
67651166868
-
Pioglitazone inhibits toll-like receptor expression and activity in human monocytes and db/db mice
-
Dasu MR, Park S, Devaraj S, Jialal I. Pioglitazone inhibits toll-like receptor expression and activity in human monocytes and db/db mice. Endocrinology (2009) 150:3457-64. doi:10.1210/en.2008-1757
-
(2009)
Endocrinology
, vol.150
, pp. 3457-3464
-
-
Dasu, M.R.1
Park, S.2
Devaraj, S.3
Jialal, I.4
-
140
-
-
0036481709
-
Synthetic peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients
-
Yang W-S, Jeng C-Y, Wu T-J, Tanaka S, Funahashi T, Matsuzawa Y, et al. Synthetic peroxisome proliferator-activated receptor-gamma agonist, rosiglitazone, increases plasma levels of adiponectin in type 2 diabetic patients. Diabetes Care (2002) 25:376-80. doi:10.2337/diacare.25.2.376
-
(2002)
Diabetes Care
, vol.25
, pp. 376-380
-
-
Yang, W.-S.1
Jeng, C.-Y.2
Wu, T.-J.3
Tanaka, S.4
Funahashi, T.5
Matsuzawa, Y.6
-
141
-
-
84991721067
-
Activation of PPAR?. by a natural flavonoid modulator, apigenin ameliorates obesity-related inflammation via regulation of macrophage polarization
-
Feng X, Weng D, Zhou F, Owen YD, Qin H, Zhao J, et al. Activation of PPAR? by a natural flavonoid modulator, apigenin ameliorates obesity-related inflammation via regulation of macrophage polarization. EBioMedicine (2016) 9:61-76. doi:10.1016/j.ebiom.2016.06.017
-
(2016)
EBioMedicine
, vol.9
, pp. 61-76
-
-
Feng, X.1
Weng, D.2
Zhou, F.3
Owen, Y.D.4
Qin, H.5
Zhao, J.6
-
142
-
-
85021269717
-
6-Shogaol attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-?
-
Han Q, Yuan Q, Meng X, Huo J, Bao Y, Xie G. 6-Shogaol attenuates LPS-induced inflammation in BV2 microglia cells by activating PPAR-?. Oncotarget (2017) 8:42001-6. doi:10.18632/oncotarget.16719
-
(2017)
Oncotarget
, vol.8
, pp. 42001-42006
-
-
Han, Q.1
Yuan, Q.2
Meng, X.3
Huo, J.4
Bao, Y.5
Xie, G.6
-
143
-
-
0037311051
-
Effects of peroxisome proliferator-activated receptor-gamma agonists on central nervous system inflammation
-
Kielian T, Drew PD. Effects of peroxisome proliferator-activated receptor-gamma agonists on central nervous system inflammation. J Neurosci Res (2003) 71:315-25. doi:10.1002/jnr.10501
-
(2003)
J Neurosci Res
, vol.71
, pp. 315-325
-
-
Kielian, T.1
Drew, P.D.2
-
144
-
-
44349112305
-
Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity
-
Kang K, Reilly SM, Karabacak V, Gangl MR, Fitzgerald K, Hatano B, et al. Adipocyte-derived Th2 cytokines and myeloid PPARdelta regulate macrophage polarization and insulin sensitivity. Cell Metab (2008) 7:485-95. doi:10.1016/j.cmet.2008.04.002
-
(2008)
Cell Metab
, vol.7
, pp. 485-495
-
-
Kang, K.1
Reilly, S.M.2
Karabacak, V.3
Gangl, M.R.4
Fitzgerald, K.5
Hatano, B.6
-
145
-
-
44349161098
-
Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance
-
Odegaard JI, Ricardo-Gonzalez RR, Red Eagle A, Vats D, Morel CR, Goforth MH, et al. Alternative M2 activation of Kupffer cells by PPARdelta ameliorates obesity-induced insulin resistance. Cell Metab (2008) 7:496-507. doi:10.1016/j.cmet.2008.04.003
-
(2008)
Cell Metab
, vol.7
, pp. 496-507
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Red Eagle, A.3
Vats, D.4
Morel, C.R.5
Goforth, M.H.6
-
146
-
-
25844473319
-
Protective effects of a peroxisome proliferator-activated receptor-beta/delta agonist in experimental autoimmune encephalomyelitis
-
Polak PE, Kalinin S, Russo Dello C, Gavrilyuk V, Sharp A, Peters JM, et al. Protective effects of a peroxisome proliferator-activated receptor-beta/delta agonist in experimental autoimmune encephalomyelitis. J Neuroimmunol (2005) 168:65-75. doi:10.1016/j.jneuroim.2005.07.006
-
(2005)
J Neuroimmunol
, vol.168
, pp. 65-75
-
-
Polak, P.E.1
Kalinin, S.2
Russo Dello, C.3
Gavrilyuk, V.4
Sharp, A.5
Peters, J.M.6
-
147
-
-
80555143144
-
Activation of PPAR?. and d by dietary punicic acid ameliorates intestinal inflammation in mice
-
Bassaganya-Riera J, DiGuardo M, Climent M, Vives C, Carbo A, Jouni ZE, et al. Activation of PPAR? and d by dietary punicic acid ameliorates intestinal inflammation in mice. Br J Nutr (2011) 106:878-86. doi:10.1017/S0007114511001188
-
(2011)
Br J Nutr
, vol.106
, pp. 878-886
-
-
Bassaganya-Riera, J.1
DiGuardo, M.2
Climent, M.3
Vives, C.4
Carbo, A.5
Jouni, Z.E.6
-
148
-
-
77954496807
-
Peroxisome proliferator-activated receptor delta agonists inhibit T helper type 1 (Th1) and Th17 responses in experimental allergic encephalomyelitis
-
Kanakasabai S, Chearwae W, Walline CC, Iams W, Adams SM, Bright JJ. Peroxisome proliferator-activated receptor delta agonists inhibit T helper type 1 (Th1) and Th17 responses in experimental allergic encephalomyelitis. Immunology (2010) 130:572-88. doi:10.1111/j.1365-2567.2010.03261.x
-
(2010)
Immunology
, vol.130
, pp. 572-588
-
-
Kanakasabai, S.1
Chearwae, W.2
Walline, C.C.3
Iams, W.4
Adams, S.M.5
Bright, J.J.6
-
149
-
-
84931052960
-
The transcriptional PPARβ/d network in human macrophages defines a unique agonist-induced activation state
-
Adhikary T, Wortmann A, Schumann T, Finkernagel F, Lieber S, Roth K, et al. The transcriptional PPARβ/d network in human macrophages defines a unique agonist-induced activation state. Nucleic Acids Res (2015) 43:5033-51. doi:10.1093/nar/gkv331
-
(2015)
Nucleic Acids Res
, vol.43
, pp. 5033-5051
-
-
Adhikary, T.1
Wortmann, A.2
Schumann, T.3
Finkernagel, F.4
Lieber, S.5
Roth, K.6
-
150
-
-
84881056831
-
MYC, metabolism, cell growth, and tumorigenesis
-
Dang CV. MYC, metabolism, cell growth, and tumorigenesis. Cold Spring Harb Perspect Med (2013) 3:a014217. doi:10.1101/cshperspect.a014217
-
(2013)
Cold Spring Harb Perspect Med
, vol.3
-
-
Dang, C.V.1
-
151
-
-
84866678666
-
In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities
-
Pello OM, Chèvre R, Laoui D, De Juan A, Lolo F, Andrés-Manzano MJ, et al. In vivo inhibition of c-MYC in myeloid cells impairs tumor-associated macrophage maturation and pro-tumoral activities. PLoS One (2012) 7:e45399. doi:10.1371/journal.pone.0045399
-
(2012)
PLoS One
, vol.7
-
-
Pello, O.M.1
Chèvre, R.2
Laoui, D.3
De Juan, A.4
Lolo, F.5
Andrés-Manzano, M.J.6
-
152
-
-
84957800096
-
Proinflammatory signal suppresses proliferation and shifts macrophage metabolism from Myc-dependent to HIF1a-dependent
-
Liu L, Lu Y, Martinez J, Bi Y, Lian G, Wang T, et al. Proinflammatory signal suppresses proliferation and shifts macrophage metabolism from Myc-dependent to HIF1a-dependent. Proc Natl Acad Sci U S A (2016) 113:1564-9. doi:10.1073/pnas.1518000113
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. 1564-1569
-
-
Liu, L.1
Lu, Y.2
Martinez, J.3
Bi, Y.4
Lian, G.5
Wang, T.6
-
153
-
-
84994797642
-
Metabolic reprogramming mediated by the mTORC2-IRF4 signaling axis is essential for macrophage alternative activation
-
Huang SC-C, Smith AM, Everts B, Colonna M, Pearce EL, Schilling JD, et al. Metabolic reprogramming mediated by the mTORC2-IRF4 signaling axis is essential for macrophage alternative activation. Immunity (2016) 45:817-30. doi:10.1016/j.immuni.2016.09.016
-
(2016)
Immunity
, vol.45
, pp. 817-830
-
-
Huang, S.C.-C.1
Smith, A.M.2
Everts, B.3
Colonna, M.4
Pearce, E.L.5
Schilling, J.D.6
-
154
-
-
38949212626
-
Interferon regulatory factor family of transcription factors and regulation of oncogenesis
-
Takaoka A, Tamura T, Taniguchi T. Interferon regulatory factor family of transcription factors and regulation of oncogenesis. Cancer Sci (2008) 99:467-78. doi:10.1111/j.1349-7006.2007.00720.x
-
(2008)
Cancer Sci
, vol.99
, pp. 467-478
-
-
Takaoka, A.1
Tamura, T.2
Taniguchi, T.3
-
155
-
-
84893834170
-
Interferon-regulatory factors determine macrophage phenotype polarization
-
Günthner R, Anders H-J. Interferon-regulatory factors determine macrophage phenotype polarization. Mediators Inflamm (2013) 2013:731023-8. doi:10.1155/2013/731023
-
(2013)
Mediators Inflamm
, vol.2013
-
-
Günthner, R.1
Anders, H.-J.2
-
156
-
-
84922546751
-
IRF5:RelA interaction targets inflammatory genes in macrophages
-
Saliba DG, Heger A, Eames HL, Oikonomopoulos S, Teixeira A, Blazek K, et al. IRF5:RelA interaction targets inflammatory genes in macrophages. Cell Rep (2014) 8:1308-17. doi:10.1016/j.celrep.2014.07.034
-
(2014)
Cell Rep
, vol.8
, pp. 1308-1317
-
-
Saliba, D.G.1
Heger, A.2
Eames, H.L.3
Oikonomopoulos, S.4
Teixeira, A.5
Blazek, K.6
-
157
-
-
79951671510
-
IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses
-
Krausgruber T, Blazek K, Smallie T, Alzabin S, Lockstone H, Sahgal N, et al. IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses. Nat Immunol (2011) 12:231-8. doi:10.1038/ni.1990
-
(2011)
Nat Immunol
, vol.12
, pp. 231-238
-
-
Krausgruber, T.1
Blazek, K.2
Smallie, T.3
Alzabin, S.4
Lockstone, H.5
Sahgal, N.6
-
158
-
-
15044345461
-
Integral role of IRF-5 in the gene induction programme activated by toll-like receptors
-
Takaoka A, Yanai H, Kondo S, Duncan G, Negishi H, Mizutani T, et al. Integral role of IRF-5 in the gene induction programme activated by toll-like receptors. Nature (2005) 434:243-9. doi:10.1038/nature03308
-
(2005)
Nature
, vol.434
, pp. 243-249
-
-
Takaoka, A.1
Yanai, H.2
Kondo, S.3
Duncan, G.4
Negishi, H.5
Mizutani, T.6
-
159
-
-
45249112573
-
Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations
-
Kristjansdottir G, Sandling JK, Bonetti A, Roos IM, Milani L, Wang C, et al. Interferon regulatory factor 5 (IRF5) gene variants are associated with multiple sclerosis in three distinct populations. J Med Genet (2008) 45:362-9. doi:10.1136/jmg.2007.055012
-
(2008)
J Med Genet
, vol.45
, pp. 362-369
-
-
Kristjansdottir, G.1
Sandling, J.K.2
Bonetti, A.3
Roos, I.M.4
Milani, L.5
Wang, C.6
-
160
-
-
84923848816
-
Aurora kinase a regulates m1 macrophage polarization and plays a role in experimental autoimmune encephalomyelitis
-
Ding L, Gu H, Gao X, Xiong S, Zheng B. Aurora kinase a regulates m1 macrophage polarization and plays a role in experimental autoimmune encephalomyelitis. Inflammation (2015) 38:800-11. doi:10.1007/s10753-014-9990-2
-
(2015)
Inflammation
, vol.38
, pp. 800-811
-
-
Ding, L.1
Gu, H.2
Gao, X.3
Xiong, S.4
Zheng, B.5
-
161
-
-
33750064259
-
Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in toll-like receptor-dependent gene induction program
-
Negishi H, Fujita Y, Yanai H, Sakaguchi S, Ouyang X, Shinohara M, et al. Evidence for licensing of IFN-gamma-induced IFN regulatory factor 1 transcription factor by MyD88 in toll-like receptor-dependent gene induction program. Proc Natl Acad Sci U S A (2006) 103:15136-41. doi:10.1073/pnas.0607181103
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 15136-15141
-
-
Negishi, H.1
Fujita, Y.2
Yanai, H.3
Sakaguchi, S.4
Ouyang, X.5
Shinohara, M.6
-
162
-
-
84931415171
-
Batf2/Irf1 induces inflammatory responses in classically activated macrophages, lipopolysaccharides, and mycobacterial infection
-
Roy S, Guler R, Parihar SP, Schmeier S, Kaczkowski B, Nishimura H, et al. Batf2/Irf1 induces inflammatory responses in classically activated macrophages, lipopolysaccharides, and mycobacterial infection. J Immunol (2015) 194:6035-44. doi:10.4049/jimmunol.1402521
-
(2015)
J Immunol
, vol.194
, pp. 6035-6044
-
-
Roy, S.1
Guler, R.2
Parihar, S.P.3
Schmeier, S.4
Kaczkowski, B.5
Nishimura, H.6
-
163
-
-
0037032471
-
IRF-8/ICSBP and IRF-1 cooperatively stimulate mouse IL-12 promoter activity in macrophages
-
Masumi A, Tamaoki S, Wang IM, Ozato K, Komuro K. IRF-8/ICSBP and IRF-1 cooperatively stimulate mouse IL-12 promoter activity in macrophages. FEBS Lett (2002) 531:348-53. doi:10.1016/S0014-5793(02)03556-1
-
(2002)
FEBS Lett
, vol.531
, pp. 348-353
-
-
Masumi, A.1
Tamaoki, S.2
Wang, I.M.3
Ozato, K.4
Komuro, K.5
-
164
-
-
84887058596
-
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
-
International Multiple Sclerosis Genetics Consortium (IMSGC)Beecham AH, Patsopoulos NA, Xifara DK, Davis MF, Kemppinen A, et al. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet (2013) 45:1353-60. doi:10.1038/ng.2770
-
(2013)
Nat Genet
, vol.45
, pp. 1353-1360
-
-
-
165
-
-
84857744447
-
Genomic regions associated with multiple sclerosis are active in B cells
-
Disanto G, Sandve GK, Berlanga-Taylor AJ, Morahan JM, Dobson R, Giovannoni G, et al. Genomic regions associated with multiple sclerosis are active in B cells. PLoS One (2012) 7:e32281. doi:10.1371/journal.pone.0032281
-
(2012)
PLoS One
, vol.7
-
-
Disanto, G.1
Sandve, G.K.2
Berlanga-Taylor, A.J.3
Morahan, J.M.4
Dobson, R.5
Giovannoni, G.6
-
166
-
-
84894280989
-
The transcription factor IRF8 activates integrin-mediated TGF-β signaling and promotes neuroinflammation
-
Yoshida Y, Yoshimi R, Yoshii H, Kim D, Dey A, Xiong H, et al. The transcription factor IRF8 activates integrin-mediated TGF-β signaling and promotes neuroinflammation. Immunity (2014) 40:187-98. doi:10.1016/j.immuni.2013.11.022
-
(2014)
Immunity
, vol.40
, pp. 187-198
-
-
Yoshida, Y.1
Yoshimi, R.2
Yoshii, H.3
Kim, D.4
Dey, A.5
Xiong, H.6
-
167
-
-
77956954197
-
The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection
-
Satoh T, Takeuchi O, Vandenbon A, Yasuda K, Tanaka Y, Kumagai Y, et al. The Jmjd3-Irf4 axis regulates M2 macrophage polarization and host responses against helminth infection. Nat Immunol (2010) 11:936-44. doi:10.1038/ni.1920
-
(2010)
Nat Immunol
, vol.11
, pp. 936-944
-
-
Satoh, T.1
Takeuchi, O.2
Vandenbon, A.3
Yasuda, K.4
Tanaka, Y.5
Kumagai, Y.6
-
168
-
-
27644548945
-
Negative regulation of toll-like-receptor signaling by IRF-4
-
Negishi H, Ohba Y, Yanai H, Takaoka A, Honma K, Yui K, et al. Negative regulation of toll-like-receptor signaling by IRF-4. Proc Natl Acad Sci U S A (2005) 102:15989-94. doi:10.1073/pnas.0508327102
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15989-15994
-
-
Negishi, H.1
Ohba, Y.2
Yanai, H.3
Takaoka, A.4
Honma, K.5
Yui, K.6
-
169
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell (2004) 116:281-97. doi:10.1016/S0092-8674(04)00045-5
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
170
-
-
84906313950
-
Identification and consequences of miRNA-target interactions-beyond repression of gene expression
-
Hausser J, Zavolan M. Identification and consequences of miRNA-target interactions-beyond repression of gene expression. Nat Rev Genet (2014) 15:599-612. doi:10.1038/nrg3765
-
(2014)
Nat Rev Genet
, vol.15
, pp. 599-612
-
-
Hausser, J.1
Zavolan, M.2
-
171
-
-
80052661268
-
Silencing microRNA-155 ameliorates experimental autoimmune encephalomyelitis
-
Murugaiyan G, Beynon V, Mittal A, Joller N, Weiner HL. Silencing microRNA-155 ameliorates experimental autoimmune encephalomyelitis. J Immunol (2011) 187:2213-21. doi:10.4049/jimmunol.1003952
-
(2011)
J Immunol
, vol.187
, pp. 2213-2221
-
-
Murugaiyan, G.1
Beynon, V.2
Mittal, A.3
Joller, N.4
Weiner, H.L.5
-
172
-
-
84055221820
-
Genetic association and altered gene expression of mir-155 in multiple sclerosis patients
-
Paraboschi EM, Soldà G, Gemmati D, Orioli E, Zeri G, Benedetti MD, et al. Genetic association and altered gene expression of mir-155 in multiple sclerosis patients. Int J Mol Sci (2011) 12:8695-712. doi:10.3390/ijms12128695
-
(2011)
Int J Mol Sci
, vol.12
, pp. 8695-8712
-
-
Paraboschi, E.M.1
Soldà, G.2
Gemmati, D.3
Orioli, E.4
Zeri, G.5
Benedetti, M.D.6
-
173
-
-
84890804750
-
miR-155 as a multiple sclerosis-relevant regulator of myeloid cell polarization
-
Moore CS, Rao VTS, Durafourt BA, Bedell BJ, Ludwin SK, Bar-Or A, et al. miR-155 as a multiple sclerosis-relevant regulator of myeloid cell polarization. Ann Neurol (2013) 74:709-20. doi:10.1002/ana.23967
-
(2013)
Ann Neurol
, vol.74
, pp. 709-720
-
-
Moore, C.S.1
Rao, V.T.S.2
Durafourt, B.A.3
Bedell, B.J.4
Ludwin, S.K.5
Bar-Or, A.6
-
174
-
-
84981316093
-
miR-155 deletion in mice overcomes neuron-intrinsic and neuron-extrinsic barriers to spinal cord repair
-
Gaudet AD, Mandrekar-Colucci S, Hall JCE, Sweet DR, Schmitt PJ, Xu X, et al. miR-155 deletion in mice overcomes neuron-intrinsic and neuron-extrinsic barriers to spinal cord repair. J Neurosci (2016) 36:8516-32. doi:10.1523/JNEUROSCI.0735-16.2016
-
(2016)
J Neurosci
, vol.36
, pp. 8516-8532
-
-
Gaudet, A.D.1
Mandrekar-Colucci, S.2
Hall, J.C.E.3
Sweet, D.R.4
Schmitt, P.J.5
Xu, X.6
-
175
-
-
38049030287
-
Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock
-
Tili E, Michaille J-J, Cimino A, Costinean S, Dumitru CD, Adair B, et al. Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol (2007) 179:5082-9. doi:10.4049/jimmunol.179.8.5082
-
(2007)
J Immunol
, vol.179
, pp. 5082-5089
-
-
Tili, E.1
Michaille, J.-J.2
Cimino, A.3
Costinean, S.4
Dumitru, C.D.5
Adair, B.6
-
176
-
-
83055176904
-
miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production
-
Cardoso AL, Guedes JR, Pereira de Almeida L, Pedroso de Lima MC. miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production. Immunology (2012) 135:73-88. doi:10.1111/j.1365-2567.2011.03514.x
-
(2012)
Immunology
, vol.135
, pp. 73-88
-
-
Cardoso, A.L.1
Guedes, J.R.2
Pereira de Almeida, L.3
Pedroso de Lima, M.C.4
-
177
-
-
80053576812
-
Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*
-
Tarassishin L, Loudig O, Bauman A, Shafit-Zagardo B, Suh H-S, Lee SC. Interferon regulatory factor 3 inhibits astrocyte inflammatory gene expression through suppression of the proinflammatory miR-155 and miR-155*. Glia (2011) 59:1911-22. doi:10.1002/glia.21233
-
(2011)
Glia
, vol.59
, pp. 1911-1922
-
-
Tarassishin, L.1
Loudig, O.2
Bauman, A.3
Shafit-Zagardo, B.4
Suh, H.-S.5
Lee, S.C.6
-
178
-
-
84904290815
-
Micro RNA detection in long-term fixed tissue of cortical glutamatergic pyramidal neurons after targeted laser-capture neuroanatomical microdissection
-
Herai RR, Stefanacci L, Hrvoj-Mihic B, Chailangkarn T, Hanson K, Semendeferi K, et al. Micro RNA detection in long-term fixed tissue of cortical glutamatergic pyramidal neurons after targeted laser-capture neuroanatomical microdissection. J Neurosci Methods (2014) 235:76-82. doi:10.1016/j.jneumeth.2014.06.028
-
(2014)
J Neurosci Methods
, vol.235
, pp. 76-82
-
-
Herai, R.R.1
Stefanacci, L.2
Hrvoj-Mihic, B.3
Chailangkarn, T.4
Hanson, K.5
Semendeferi, K.6
-
179
-
-
33846845071
-
MicroRNA-155 is induced during the macrophage inflammatory response
-
O'Connell RM, Taganov KD, Boldin MP, Cheng G, Baltimore D. MicroRNA-155 is induced during the macrophage inflammatory response. Proc Natl Acad Sci U S A (2007) 104:1604-9. doi:10.1073/pnas.0610731104
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 1604-1609
-
-
O'Connell, R.M.1
Taganov, K.D.2
Boldin, M.P.3
Cheng, G.4
Baltimore, D.5
-
180
-
-
62449173209
-
MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells
-
Ceppi M, Pereira PM, Dunand-Sauthier I, Barras E, Reith W, Santos MA, et al. MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells. Proc Natl Acad Sci U S A (2009) 106:2735-40. doi:10.1073/pnas.0811073106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 2735-2740
-
-
Ceppi, M.1
Pereira, P.M.2
Dunand-Sauthier, I.3
Barras, E.4
Reith, W.5
Santos, M.A.6
-
181
-
-
84893402227
-
Next-generation sequencing of microRNAs uncovers expression signatures in polarized macrophages
-
Cobos Jiménez V, Bradley EJ, Willemsen AM, van Kampen AHC, Baas F, Kootstra NA. Next-generation sequencing of microRNAs uncovers expression signatures in polarized macrophages. Physiol Genomics (2013) 46:91-103. doi:10.1152/physiolgenomics.00140.2013
-
(2013)
Physiol Genomics
, vol.46
, pp. 91-103
-
-
Cobos Jiménez, V.1
Bradley, E.J.2
Willemsen, A.M.3
van Kampen, A.H.C.4
Baas, F.5
Kootstra, N.A.6
-
182
-
-
84862697885
-
Identifying functional microRNAs in macrophages with polarized phenotypes
-
Graff JW, Dickson AM, Clay G, McCaffrey AP, Wilson ME. Identifying functional microRNAs in macrophages with polarized phenotypes. J Biol Chem (2012) 287:21816-25. doi:10.1074/jbc.M111.327031
-
(2012)
J Biol Chem
, vol.287
, pp. 21816-21825
-
-
Graff, J.W.1
Dickson, A.M.2
Clay, G.3
McCaffrey, A.P.4
Wilson, M.E.5
-
183
-
-
84936146348
-
miR-155 is essential for inflammation-induced hippocampal neurogenic dysfunction
-
Woodbury ME, Freilich RW, Cheng CJ, Asai H, Ikezu S, Boucher JD, et al. miR-155 is essential for inflammation-induced hippocampal neurogenic dysfunction. J Neurosci (2015) 35:9764-81. doi:10.1523/JNEUROSCI.4790-14.2015
-
(2015)
J Neurosci
, vol.35
, pp. 9764-9781
-
-
Woodbury, M.E.1
Freilich, R.W.2
Cheng, C.J.3
Asai, H.4
Ikezu, S.5
Boucher, J.D.6
-
184
-
-
84893202052
-
Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia
-
Freilich RW, Woodbury ME, Ikezu T. Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia. PLoS One (2013) 8:e79416. doi:10.1371/journal.pone.0079416
-
(2013)
PLoS One
, vol.8
-
-
Freilich, R.W.1
Woodbury, M.E.2
Ikezu, T.3
-
185
-
-
84875255948
-
Expression profiles of miRNAs in polarized macrophages
-
Zhang Y, Zhang M, Zhong M, Suo Q, Lv K. Expression profiles of miRNAs in polarized macrophages. Int J Mol Med (2013) 31:797-802. doi:10.3892/ijmm.2013.1260
-
(2013)
Int J Mol Med
, vol.31
, pp. 797-802
-
-
Zhang, Y.1
Zhang, M.2
Zhong, M.3
Suo, Q.4
Lv, K.5
-
186
-
-
84934903985
-
Exosome-delivered microRNAs modulate the inflammatory response to endotoxin
-
Alexander M, Hu R, Runtsch MC, Kagele DA, Mosbruger TL, Tolmachova T, et al. Exosome-delivered microRNAs modulate the inflammatory response to endotoxin. Nat Commun (2015) 6:7321. doi:10.1038/ncomms8321
-
(2015)
Nat Commun
, vol.6
, pp. 7321
-
-
Alexander, M.1
Hu, R.2
Runtsch, M.C.3
Kagele, D.A.4
Mosbruger, T.L.5
Tolmachova, T.6
-
187
-
-
84941247739
-
In vivo inhibition of miR-155 promotes recovery after experimental mouse stroke
-
Caballero-Garrido E, Pena-Philippides JC, Lordkipanidze T, Bragin D, Yang Y, Erhardt EB, et al. In vivo inhibition of miR-155 promotes recovery after experimental mouse stroke. J Neurosci (2015) 35:12446-64. doi:10.1523/JNEUROSCI.1641-15.2015
-
(2015)
J Neurosci
, vol.35
, pp. 12446-12464
-
-
Caballero-Garrido, E.1
Pena-Philippides, J.C.2
Lordkipanidze, T.3
Bragin, D.4
Yang, Y.5
Erhardt, E.B.6
-
189
-
-
84946822396
-
MicroRNA-223 regulates the differentiation and function of intestinal dendritic cells and macrophages by targeting C/EBPβ
-
Zhou H, Xiao J, Wu N, Liu C, Xu J, Liu F, et al. MicroRNA-223 regulates the differentiation and function of intestinal dendritic cells and macrophages by targeting C/EBPβ. Cell Rep (2015) 13:1149-60. doi:10.1016/j.celrep.2015.09.073
-
(2015)
Cell Rep
, vol.13
, pp. 1149-1160
-
-
Zhou, H.1
Xiao, J.2
Wu, N.3
Liu, C.4
Xu, J.5
Liu, F.6
-
190
-
-
14844340837
-
The protooncogene c-Maf is an essential transcription factor for IL-10 gene expression in macrophages
-
Cao S, Liu J, Song L, Ma X. The protooncogene c-Maf is an essential transcription factor for IL-10 gene expression in macrophages. J Immunol (2005) 174:3484-92. doi:10.4049/jimmunol.174.6.3484
-
(2005)
J Immunol
, vol.174
, pp. 3484-3492
-
-
Cao, S.1
Liu, J.2
Song, L.3
Ma, X.4
-
191
-
-
0037111372
-
Differential regulation of IL-12 and IL-10 gene expression in macrophages by the basic leucine zipper transcription factor c-Maf fibrosarcoma
-
Cao S, Liu J, Chesi M, Bergsagel PL, Ho I-C, Donnelly RP, et al. Differential regulation of IL-12 and IL-10 gene expression in macrophages by the basic leucine zipper transcription factor c-Maf fibrosarcoma. J Immunol (2002) 169:5715-25. doi:10.4049/jimmunol.169.10.5715
-
(2002)
J Immunol
, vol.169
, pp. 5715-5725
-
-
Cao, S.1
Liu, J.2
Chesi, M.3
Bergsagel, P.L.4
Ho, I.-C.5
Donnelly, R.P.6
-
192
-
-
84871804547
-
Differential activation and functional specialization of miR-146 and miR-155 in innate immune sensing
-
Schulte LN, Westermann AJ, Vogel J. Differential activation and functional specialization of miR-146 and miR-155 in innate immune sensing. Nucleic Acids Res (2013) 41:542-53. doi:10.1093/nar/gks1030
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 542-553
-
-
Schulte, L.N.1
Westermann, A.J.2
Vogel, J.3
-
193
-
-
0026501412
-
Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6
-
Natsuka S, Akira S, Nishio Y, Hashimoto S, Sugita T, Isshiki H, et al. Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6. Blood (1992) 79:460-6
-
(1992)
Blood
, vol.79
, pp. 460-466
-
-
Natsuka, S.1
Akira, S.2
Nishio, Y.3
Hashimoto, S.4
Sugita, T.5
Isshiki, H.6
-
194
-
-
84856295957
-
C5a-regulated CCAAT/enhancer-binding proteins β and d are essential in Fc?. receptor-mediated inflammatory cytokine and chemokine production in macrophages
-
Yan C, Zhu M, Staiger J, Johnson PF, Gao H. C5a-regulated CCAAT/enhancer-binding proteins β and d are essential in Fc? receptor-mediated inflammatory cytokine and chemokine production in macrophages. J Biol Chem (2012) 287:3217-30. doi:10.1074/jbc.M111.280834
-
(2012)
J Biol Chem
, vol.287
, pp. 3217-3230
-
-
Yan, C.1
Zhu, M.2
Staiger, J.3
Johnson, P.F.4
Gao, H.5
-
195
-
-
0029024113
-
Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient mice
-
Screpanti I, Romani L, Musiani P, Modesti A, Fattori E, Lazzaro D, et al. Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient mice. EMBO J (1995) 14:1932-41
-
(1995)
EMBO J
, vol.14
, pp. 1932-1941
-
-
Screpanti, I.1
Romani, L.2
Musiani, P.3
Modesti, A.4
Fattori, E.5
Lazzaro, D.6
-
196
-
-
0037090244
-
C/EBP beta gene inactivation causes both impaired and enhanced gene expression and inverse regulation of IL-12 p40 and p35 mRNAs in macrophages
-
Gorgoni B, Maritano D, Marthyn P, Righi M, Poli V. C/EBP beta gene inactivation causes both impaired and enhanced gene expression and inverse regulation of IL-12 p40 and p35 mRNAs in macrophages. J Immunol (2002) 168:4055-62. doi:10.4049/jimmunol.168.8.4055
-
(2002)
J Immunol
, vol.168
, pp. 4055-4062
-
-
Gorgoni, B.1
Maritano, D.2
Marthyn, P.3
Righi, M.4
Poli, V.5
-
197
-
-
0028889432
-
Nuclear factor-IL6 activates the human IL-4 promoter in T cells
-
Davydov IV, Krammer PH, Li-Weber M. Nuclear factor-IL6 activates the human IL-4 promoter in T cells. J Immunol (1995) 155:5273-9
-
(1995)
J Immunol
, vol.155
, pp. 5273-5279
-
-
Davydov, I.V.1
Krammer, P.H.2
Li-Weber, M.3
-
198
-
-
0033198185
-
A composite C/EBP binding site is essential for the activity of the promoter of the IL-3/IL-5/granulocyte-macrophage colony-stimulating factor receptor beta c gene
-
van Dijk TB, Baltus B, Raaijmakers JA, Lammers JW, Koenderman L, de Groot RP. A composite C/EBP binding site is essential for the activity of the promoter of the IL-3/IL-5/granulocyte-macrophage colony-stimulating factor receptor beta c gene. J Immunol (1999) 163:2674-80
-
(1999)
J Immunol
, vol.163
, pp. 2674-2680
-
-
van Dijk, T.B.1
Baltus, B.2
Raaijmakers, J.A.3
Lammers, J.W.4
Koenderman, L.5
de Groot, R.P.6
-
199
-
-
78651247933
-
MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-a-PU.1 pathway
-
Ponomarev ED, Veremeyko T, Barteneva N, Krichevsky AM, Weiner HL. MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-a-PU.1 pathway. Nat Med (2011) 17:64-70. doi:10.1038/nm.2266
-
(2011)
Nat Med
, vol.17
, pp. 64-70
-
-
Ponomarev, E.D.1
Veremeyko, T.2
Barteneva, N.3
Krichevsky, A.M.4
Weiner, H.L.5
-
200
-
-
84982252281
-
Dynamic modulation of microglia/macrophage polarization by miR-124 after focal cerebral ischemia
-
Hamzei Taj S, Kho W, Aswendt M, Collmann FM, Green C, Adamczak J, et al. Dynamic modulation of microglia/macrophage polarization by miR-124 after focal cerebral ischemia. J Neuroimmune Pharmacol (2016) 11:733-48. doi:10.1007/s11481-016-9700-y
-
(2016)
J Neuroimmune Pharmacol
, vol.11
, pp. 733-748
-
-
Hamzei Taj, S.1
Kho, W.2
Aswendt, M.3
Collmann, F.M.4
Green, C.5
Adamczak, J.6
-
201
-
-
84879118942
-
MicroRNA let-7c regulates macrophage polarization
-
Banerjee S, Xie N, Cui H, Tan Z, Yang S, Icyuz M, et al. MicroRNA let-7c regulates macrophage polarization. J Immunol (2013) 190:6542-9. doi:10.4049/jimmunol.1202496
-
(2013)
J Immunol
, vol.190
, pp. 6542-6549
-
-
Banerjee, S.1
Xie, N.2
Cui, H.3
Tan, Z.4
Yang, S.5
Icyuz, M.6
-
202
-
-
35348929402
-
A cellular micro-RNA, let-7i, regulates toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection
-
Chen X-M, Splinter PL, O'Hara SP, LaRusso NF. A cellular micro-RNA, let-7i, regulates toll-like receptor 4 expression and contributes to cholangiocyte immune responses against Cryptosporidium parvum infection. J Biol Chem (2007) 282:28929-38. doi:10.1074/jbc.M702633200
-
(2007)
J Biol Chem
, vol.282
, pp. 28929-28938
-
-
Chen, X.-M.1
Splinter, P.L.2
O'Hara, S.P.3
LaRusso, N.F.4
-
203
-
-
84942296520
-
Association of TLR4 polymorphisms with Mycobacterium avium subspecies paratuberculosis infection status in Canadian Holsteins
-
Sharma BS, Abo-Ismail MK, Schenkel FS, You Q, Verschoor CP, Pant SD, et al. Association of TLR4 polymorphisms with Mycobacterium avium subspecies paratuberculosis infection status in Canadian Holsteins. Anim Genet (2015) 46:560-5. doi:10.1111/age.12333
-
(2015)
Anim Genet
, vol.46
, pp. 560-565
-
-
Sharma, B.S.1
Abo-Ismail, M.K.2
Schenkel, F.S.3
You, Q.4
Verschoor, C.P.5
Pant, S.D.6
-
204
-
-
84957439106
-
MicroRNA-125b regulates microglia activation and motor neuron death in ALS
-
Parisi C, Napoli G, Amadio S, Spalloni A, Apolloni S, Longone P, et al. MicroRNA-125b regulates microglia activation and motor neuron death in ALS. Cell Death Differ (2016) 23:531-41. doi:10.1038/cdd.2015.153
-
(2016)
Cell Death Differ
, vol.23
, pp. 531-541
-
-
Parisi, C.1
Napoli, G.2
Amadio, S.3
Spalloni, A.4
Apolloni, S.5
Longone, P.6
-
205
-
-
84926248014
-
MicroRNA let-7 modulates the immune response to Mycobacterium tuberculosis infection via control of A20, an inhibitor of the NF-?B pathway
-
Kumar M, Sahu SK, Kumar R, Subuddhi A, Maji RK, Jana K, et al. MicroRNA let-7 modulates the immune response to Mycobacterium tuberculosis infection via control of A20, an inhibitor of the NF-?B pathway. Cell Host Microbe (2015) 17:345-56. doi:10.1016/j.chom.2015.01.007
-
(2015)
Cell Host Microbe
, vol.17
, pp. 345-356
-
-
Kumar, M.1
Sahu, S.K.2
Kumar, R.3
Subuddhi, A.4
Maji, R.K.5
Jana, K.6
-
206
-
-
84861577379
-
An unconventional role for miRNA: let-7 activates toll-like receptor 7 and causes neurodegeneration
-
Lehmann SM, Krüger C, Park B, Derkow K, Rosenberger K, Baumgart J, et al. An unconventional role for miRNA: let-7 activates toll-like receptor 7 and causes neurodegeneration. Nat Neurosci (2012) 15:827-35. doi:10.1038/nn.3113
-
(2012)
Nat Neurosci
, vol.15
, pp. 827-835
-
-
Lehmann, S.M.1
Krüger, C.2
Park, B.3
Derkow, K.4
Rosenberger, K.5
Baumgart, J.6
-
207
-
-
84971201128
-
miRNA let-7b modulates macrophage polarization and enhances tumor-associated macrophages to promote angiogenesis and mobility in prostate cancer
-
Wang Z, Xu L, Hu Y, Huang Y, Zhang Y, Zheng X, et al. miRNA let-7b modulates macrophage polarization and enhances tumor-associated macrophages to promote angiogenesis and mobility in prostate cancer. Sci Rep (2016) 6:25602. doi:10.1038/srep25602
-
(2016)
Sci Rep
, vol.6
, pp. 25602
-
-
Wang, Z.1
Xu, L.2
Hu, Y.3
Huang, Y.4
Zhang, Y.5
Zheng, X.6
-
208
-
-
0028919209
-
Arginase induction by suppressors of nitric oxide synthesis (IL-4, IL-10 and PGE2) in murine bone-marrow-derived macrophages
-
Corraliza IM, Soler G, Eichmann K, Modolell M. Arginase induction by suppressors of nitric oxide synthesis (IL-4, IL-10 and PGE2) in murine bone-marrow-derived macrophages. Biochem Biophys Res Commun (1995) 206:667-73. doi:10.1006/bbrc.1995.1094
-
(1995)
Biochem Biophys Res Commun
, vol.206
, pp. 667-673
-
-
Corraliza, I.M.1
Soler, G.2
Eichmann, K.3
Modolell, M.4
-
209
-
-
0032102990
-
Alternative metabolic states in murine macrophages reflected by the nitric oxide synthase/arginase balance: competitive regulation by CD4+ T cells correlates with Th1/Th2 phenotype
-
Munder M, Eichmann K, Modolell M. Alternative metabolic states in murine macrophages reflected by the nitric oxide synthase/arginase balance: competitive regulation by CD4+ T cells correlates with Th1/Th2 phenotype. J Immunol (1998) 160:5347-54
-
(1998)
J Immunol
, vol.160
, pp. 5347-5354
-
-
Munder, M.1
Eichmann, K.2
Modolell, M.3
-
210
-
-
85017144052
-
Macrophage immunometabolism: where are we (going)?
-
Van den Bossche J, O'Neill LA, Menon D. Macrophage immunometabolism: where are we (going)? Trends Immunol (2017) 38:395-406. doi:10.1016/j.it.2017.03.001
-
(2017)
Trends Immunol
, vol.38
, pp. 395-406
-
-
Van den Bossche, J.1
O'Neill, L.A.2
Menon, D.3
-
211
-
-
0023140462
-
Rates of utilization and fates of glucose, glutamine, pyruvate, fatty acids and ketone bodies by mouse macrophages
-
Newsholme P, Gordon S, Newsholme EA. Rates of utilization and fates of glucose, glutamine, pyruvate, fatty acids and ketone bodies by mouse macrophages. Biochem J (1987) 242:631-6. doi:10.1042/bj2420631
-
(1987)
Biochem J
, vol.242
, pp. 631-636
-
-
Newsholme, P.1
Gordon, S.2
Newsholme, E.A.3
-
212
-
-
85006768050
-
The metabolism of tumors in the body
-
Warburg O, Wind F, Negelein E. The metabolism of tumors in the body. J Gen Physiol (1927) 8:519-30. doi:10.1085/jgp.8.6.519
-
(1927)
J Gen Physiol
, vol.8
, pp. 519-530
-
-
Warburg, O.1
Wind, F.2
Negelein, E.3
-
213
-
-
84992179972
-
Mitochondrial dysfunction prevents repolarization of inflammatory macrophages
-
Van den Bossche J, Baardman J, Otto NA, van der Velden S, Neele AE, van den Berg SM, et al. Mitochondrial dysfunction prevents repolarization of inflammatory macrophages. Cell Rep (2016) 17:684-96. doi:10.1016/j.celrep.2016.09.008
-
(2016)
Cell Rep
, vol.17
, pp. 684-696
-
-
Van den Bossche, J.1
Baardman, J.2
Otto, N.A.3
van der Velden, S.4
Neele, A.E.5
van den Berg, S.M.6
-
214
-
-
84862016400
-
The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism
-
Haschemi A, Kosma P, Gille L, Evans CR, Burant CF, Starkl P, et al. The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism. Cell Metab (2012) 15:813-26. doi:10.1016/j.cmet.2012.04.023
-
(2012)
Cell Metab
, vol.15
, pp. 813-826
-
-
Haschemi, A.1
Kosma, P.2
Gille, L.3
Evans, C.R.4
Burant, C.F.5
Starkl, P.6
-
215
-
-
84949426263
-
Metabolic characterization of polarized M1 and M2 bone marrow-derived macrophages using real-time extracellular flux analysis
-
Van den Bossche J, Baardman J, de Winther MPJ. Metabolic characterization of polarized M1 and M2 bone marrow-derived macrophages using real-time extracellular flux analysis. J Vis Exp (2015) 105:e53424. doi:10.3791/53424
-
(2015)
J Vis Exp
, vol.105
-
-
Van den Bossche, J.1
Baardman, J.2
de Winther, M.P.J.3
-
216
-
-
33745428666
-
Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation
-
Vats D, Mukundan L, Odegaard JI, Zhang L, Smith KL, Morel CR, et al. Oxidative metabolism and PGC-1beta attenuate macrophage-mediated inflammation. Cell Metab (2006) 4:13-24. doi:10.1016/j.cmet.2006.05.011
-
(2006)
Cell Metab
, vol.4
, pp. 13-24
-
-
Vats, D.1
Mukundan, L.2
Odegaard, J.I.3
Zhang, L.4
Smith, K.L.5
Morel, C.R.6
-
217
-
-
84990845578
-
Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages
-
Mills EL, Kelly B, Logan A, Costa ASH, Varma M, Bryant CE, et al. Succinate dehydrogenase supports metabolic repurposing of mitochondria to drive inflammatory macrophages. Cell (2016) 167:457-70.e13. doi:10.1016/j.cell.2016.08.064
-
(2016)
Cell
, vol.167
, pp. 457-470
-
-
Mills, E.L.1
Kelly, B.2
Logan, A.3
Costa, A.S.H.4
Varma, M.5
Bryant, C.E.6
-
218
-
-
84992179981
-
A metabolic roadblock in inflammatory macrophages
-
O'Neill LAJ. A metabolic roadblock in inflammatory macrophages. Cell Rep (2016) 17:625-6. doi:10.1016/j.celrep.2016.09.085
-
(2016)
Cell Rep
, vol.17
, pp. 625-626
-
-
O'Neill, L.A.J.1
-
219
-
-
84976869322
-
Immunoresponsive gene 1 and itaconate inhibit succinate dehydrogenase to modulate intracellular succinate levels
-
Cordes T, Wallace M, Michelucci A, Divakaruni AS, Sapcariu SC, Sousa C, et al. Immunoresponsive gene 1 and itaconate inhibit succinate dehydrogenase to modulate intracellular succinate levels. J Biol Chem (2016) 291:14274-84. doi:10.1074/jbc.M115.685792
-
(2016)
J Biol Chem
, vol.291
, pp. 14274-14284
-
-
Cordes, T.1
Wallace, M.2
Michelucci, A.3
Divakaruni, A.S.4
Sapcariu, S.C.5
Sousa, C.6
-
220
-
-
0036092801
-
Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects
-
Dai X-M, Ryan GR, Hapel AJ, Dominguez MG, Russell RG, Kapp S, et al. Targeted disruption of the mouse colony-stimulating factor 1 receptor gene results in osteopetrosis, mononuclear phagocyte deficiency, increased primitive progenitor cell frequencies, and reproductive defects. Blood (2002) 99:111-20. doi:10.1182/blood.V99.1.111
-
(2002)
Blood
, vol.99
, pp. 111-120
-
-
Dai, X.-M.1
Ryan, G.R.2
Hapel, A.J.3
Dominguez, M.G.4
Russell, R.G.5
Kapp, S.6
-
221
-
-
0028085513
-
Cloning and mRNA expression analysis of a novel human protooncogene, c-mer
-
Graham DK, Dawson TL, Mullaney DL, Snodgrass HR, Earp HS. Cloning and mRNA expression analysis of a novel human protooncogene, c-mer. Cell Growth Differ (1994) 5:647-57
-
(1994)
Cell Growth Differ
, vol.5
, pp. 647-657
-
-
Graham, D.K.1
Dawson, T.L.2
Mullaney, D.L.3
Snodgrass, H.R.4
Earp, H.S.5
-
222
-
-
0029029248
-
Cloning and developmental expression analysis of the murine c-mer tyrosine kinase
-
Graham DK, Bowman GW, Dawson TL, Stanford WL, Earp HS, Snodgrass HR. Cloning and developmental expression analysis of the murine c-mer tyrosine kinase. Oncogene (1995) 10:2349-59
-
(1995)
Oncogene
, vol.10
, pp. 2349-2359
-
-
Graham, D.K.1
Bowman, G.W.2
Dawson, T.L.3
Stanford, W.L.4
Earp, H.S.5
Snodgrass, H.R.6
-
223
-
-
0028206124
-
Molecular cloning of a novel receptor tyrosine kinase gene, STK, derived from enriched hematopoietic stem cells
-
Iwama A, Okano K, Sudo T, Matsuda Y, Suda T. Molecular cloning of a novel receptor tyrosine kinase gene, STK, derived from enriched hematopoietic stem cells. Blood (1994) 83:3160-9
-
(1994)
Blood
, vol.83
, pp. 3160-3169
-
-
Iwama, A.1
Okano, K.2
Sudo, T.3
Matsuda, Y.4
Suda, T.5
-
224
-
-
0027318311
-
A novel putative receptor protein tyrosine kinase of the met family
-
Ronsin C, Muscatelli F, Mattei MG, Breathnach R. A novel putative receptor protein tyrosine kinase of the met family. Oncogene (1993) 8:1195-202
-
(1993)
Oncogene
, vol.8
, pp. 1195-1202
-
-
Ronsin, C.1
Muscatelli, F.2
Mattei, M.G.3
Breathnach, R.4
-
225
-
-
0028985212
-
Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6
-
Varnum BC, Young C, Elliott G, Garcia A, Bartley TD, Fridell YW, et al. Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6. Nature (1995) 373:623-6. doi:10.1038/373623a0
-
(1995)
Nature
, vol.373
, pp. 623-626
-
-
Varnum, B.C.1
Young, C.2
Elliott, G.3
Garcia, A.4
Bartley, T.D.5
Fridell, Y.W.6
-
226
-
-
0029910706
-
Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases
-
Nagata K, Ohashi K, Nakano T, Arita H, Zong C, Hanafusa H, et al. Identification of the product of growth arrest-specific gene 6 as a common ligand for Axl, Sky, and Mer receptor tyrosine kinases. J Biol Chem (1996) 271:30022-7. doi:10.1074/jbc.271.47.30022
-
(1996)
J Biol Chem
, vol.271
, pp. 30022-30027
-
-
Nagata, K.1
Ohashi, K.2
Nakano, T.3
Arita, H.4
Zong, C.5
Hanafusa, H.6
-
227
-
-
0028139182
-
Identification of the ron gene product as the receptor for the human macrophage stimulating protein
-
Wang MH, Ronsin C, Gesnel MC, Coupey L, Skeel A, Leonard EJ, et al. Identification of the ron gene product as the receptor for the human macrophage stimulating protein. Science (1994) 266:117-9. doi:10.1126/science.7939629
-
(1994)
Science
, vol.266
, pp. 117-119
-
-
Wang, M.H.1
Ronsin, C.2
Gesnel, M.C.3
Coupey, L.4
Skeel, A.5
Leonard, E.J.6
-
228
-
-
0027957058
-
Proteolytic conversion of single chain precursor macrophage-stimulating protein to a biologically active heterodimer by contact enzymes of the coagulation cascade
-
Wang MH, Yoshimura T, Skeel A, Leonard EJ. Proteolytic conversion of single chain precursor macrophage-stimulating protein to a biologically active heterodimer by contact enzymes of the coagulation cascade. J Biol Chem (1994) 269:3436-40
-
(1994)
J Biol Chem
, vol.269
, pp. 3436-3440
-
-
Wang, M.H.1
Yoshimura, T.2
Skeel, A.3
Leonard, E.J.4
-
229
-
-
0028352123
-
Macrophage-stimulating protein inhibits induction of nitric oxide production by endotoxin-or cytokine-stimulated mouse macrophages
-
Wang MH, Cox GW, Yoshimura T, Sheffler LA, Skeel A, Leonard EJ. Macrophage-stimulating protein inhibits induction of nitric oxide production by endotoxin-or cytokine-stimulated mouse macrophages. J Biol Chem (1994) 269:14027-31
-
(1994)
J Biol Chem
, vol.269
, pp. 14027-14031
-
-
Wang, M.H.1
Cox, G.W.2
Yoshimura, T.3
Sheffler, L.A.4
Skeel, A.5
Leonard, E.J.6
-
230
-
-
0032741542
-
Negative regulation of macrophage activation in response to IFN-gamma and lipopolysaccharide by the STK/RON receptor tyrosine kinase
-
Liu QP, Fruit K, Ward J, Correll PH. Negative regulation of macrophage activation in response to IFN-gamma and lipopolysaccharide by the STK/RON receptor tyrosine kinase. J Immunol (1999) 163:6606-13
-
(1999)
J Immunol
, vol.163
, pp. 6606-6613
-
-
Liu, Q.P.1
Fruit, K.2
Ward, J.3
Correll, P.H.4
-
231
-
-
0037064056
-
Activation of the RON receptor tyrosine kinase by macrophage-stimulating protein inhibits inducible cyclooxygenase-2 expression in murine macrophages
-
Zhou Y-Q, Chen Y-Q, Fisher JH, Wang M-H. Activation of the RON receptor tyrosine kinase by macrophage-stimulating protein inhibits inducible cyclooxygenase-2 expression in murine macrophages. J Biol Chem (2002) 277:38104-10. doi:10.1074/jbc.M206167200
-
(2002)
J Biol Chem
, vol.277
, pp. 38104-38110
-
-
Zhou, Y.-Q.1
Chen, Y.-Q.2
Fisher, J.H.3
Wang, M.-H.4
-
232
-
-
0033559140
-
A novel receptor tyrosine kinase, Mer, inhibits TNF-alpha production and lipopolysaccharide-induced endotoxic shock
-
Camenisch TD, Koller BH, Earp HS, Matsushima GK. A novel receptor tyrosine kinase, Mer, inhibits TNF-alpha production and lipopolysaccharide-induced endotoxic shock. J Immunol (1999) 162:3498-503
-
(1999)
J Immunol
, vol.162
, pp. 3498-3503
-
-
Camenisch, T.D.1
Koller, B.H.2
Earp, H.S.3
Matsushima, G.K.4
-
233
-
-
1642443959
-
Macrophage-stimulating protein, the ligand for the stem cell-derived tyrosine kinase/RON receptor tyrosine kinase, inhibits IL-12 production by primary peritoneal macrophages stimulated with IFN-gamma and lipopolysaccharide
-
Morrison AC, Wilson CB, Ray M, Correll PH. Macrophage-stimulating protein, the ligand for the stem cell-derived tyrosine kinase/RON receptor tyrosine kinase, inhibits IL-12 production by primary peritoneal macrophages stimulated with IFN-gamma and lipopolysaccharide. J Immunol (2004) 172:1825-32. doi:10.4049/jimmunol.172.3.1825
-
(2004)
J Immunol
, vol.172
, pp. 1825-1832
-
-
Morrison, A.C.1
Wilson, C.B.2
Ray, M.3
Correll, P.H.4
-
234
-
-
0035854442
-
Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family
-
Lu Q, Lemke G. Homeostatic regulation of the immune system by receptor tyrosine kinases of the Tyro 3 family. Science (2001) 293:306-11. doi:10.1126/science.1061663
-
(2001)
Science
, vol.293
, pp. 306-311
-
-
Lu, Q.1
Lemke, G.2
-
235
-
-
84939504757
-
The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung
-
Fujimori T, Grabiec AM, Kaur M, Bell TJ, Fujino N, Cook PC, et al. The Axl receptor tyrosine kinase is a discriminator of macrophage function in the inflamed lung. Mucosal Immunol (2015) 8:1021-30. doi:10.1038/mi.2014.129
-
(2015)
Mucosal Immunol
, vol.8
, pp. 1021-1030
-
-
Fujimori, T.1
Grabiec, A.M.2
Kaur, M.3
Bell, T.J.4
Fujino, N.5
Cook, P.C.6
-
236
-
-
58549094584
-
Efficient colonic mucosal wound repair requires Trem2 signaling
-
Seno H, Miyoshi H, Brown SL, Geske MJ, Colonna M, Stappenbeck TS. Efficient colonic mucosal wound repair requires Trem2 signaling. Proc Natl Acad Sci U S A (2009) 106:256-61. doi:10.1073/pnas.0803343106
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 256-261
-
-
Seno, H.1
Miyoshi, H.2
Brown, S.L.3
Geske, M.J.4
Colonna, M.5
Stappenbeck, T.S.6
-
237
-
-
36549033197
-
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions
-
Nahrendorf M, Swirski FK, Aikawa E, Stangenberg L, Wurdinger T, Figueiredo J-L, et al. The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions. J Exp Med (2007) 204:3037-47. doi:10.1084/jem.20070885
-
(2007)
J Exp Med
, vol.204
, pp. 3037-3047
-
-
Nahrendorf, M.1
Swirski, F.K.2
Aikawa, E.3
Stangenberg, L.4
Wurdinger, T.5
Figueiredo, J.-L.6
-
238
-
-
34547683384
-
Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol
-
Kato M, Li J, Chuang JL, Chuang DT. Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol. Structure (2007) 15:992-1004. doi:10.1016/j.str.2007.07.001
-
(2007)
Structure
, vol.15
, pp. 992-1004
-
-
Kato, M.1
Li, J.2
Chuang, J.L.3
Chuang, D.T.4
-
239
-
-
84920481006
-
Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation
-
Gerriets VA, Kishton RJ, Nichols AG, Macintyre AN, Inoue M, Ilkayeva O, et al. Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation. J Clin Invest (2015) 125:194-207. doi:10.1172/JCI76012
-
(2015)
J Clin Invest
, vol.125
, pp. 194-207
-
-
Gerriets, V.A.1
Kishton, R.J.2
Nichols, A.G.3
Macintyre, A.N.4
Inoue, M.5
Ilkayeva, O.6
-
240
-
-
84866423965
-
Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis
-
Gold R, Kappos L, Arnold DL, Bar-Or A, Giovannoni G, Selmaj K, et al. Placebo-controlled phase 3 study of oral BG-12 for relapsing multiple sclerosis. N Engl J Med (2012) 367:1098-107. doi:10.1056/NEJMoa1114287
-
(2012)
N Engl J Med
, vol.367
, pp. 1098-1107
-
-
Gold, R.1
Kappos, L.2
Arnold, D.L.3
Bar-Or, A.4
Giovannoni, G.5
Selmaj, K.6
-
241
-
-
84930937164
-
Dimethyl fumarate modulates antioxidant and lipid metabolism in oligodendrocytes
-
Huang H, Taraboletti A, Shriver LP. Dimethyl fumarate modulates antioxidant and lipid metabolism in oligodendrocytes. Redox Biol (2015) 5:169-75. doi:10.1016/j.redox.2015.04.011
-
(2015)
Redox Biol
, vol.5
, pp. 169-175
-
-
Huang, H.1
Taraboletti, A.2
Shriver, L.P.3
-
242
-
-
0030828067
-
Influence of monomethylfumarate on monocytic cytokine formation-explanation for adverse and therapeutic effects in psoriasis?
-
Asadullah K, Schmid H, Friedrich M, Randow F, Volk HD, Sterry W, et al. Influence of monomethylfumarate on monocytic cytokine formation-explanation for adverse and therapeutic effects in psoriasis? Arch Dermatol Res (1997) 289:623-30. doi:10.1007/s004030050251
-
(1997)
Arch Dermatol Res
, vol.289
, pp. 623-630
-
-
Asadullah, K.1
Schmid, H.2
Friedrich, M.3
Randow, F.4
Volk, H.D.5
Sterry, W.6
-
243
-
-
84865009934
-
Dimethyl fumarate inhibits dendritic cell maturation via nuclear factor ?B (NF-?B) and extracellular signal-regulated kinase 1 and 2 (ERK1/2) and mitogen stress-activated kinase 1 (MSK1) signaling
-
Peng H, Guerau-de-Arellano M, Mehta VB, Yang Y, Huss DJ, Papenfuss TL, et al. Dimethyl fumarate inhibits dendritic cell maturation via nuclear factor ?B (NF-?B) and extracellular signal-regulated kinase 1 and 2 (ERK1/2) and mitogen stress-activated kinase 1 (MSK1) signaling. J Biol Chem (2012) 287:28017-26. doi:10.1074/jbc.M112.383380
-
(2012)
J Biol Chem
, vol.287
, pp. 28017-28026
-
-
Peng, H.1
Guerau-de-Arellano, M.2
Mehta, V.B.3
Yang, Y.4
Huss, D.J.5
Papenfuss, T.L.6
-
244
-
-
79952136166
-
Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway
-
Linker RA, Lee D-H, Ryan S, van Dam AM, Conrad R, Bista P, et al. Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway. Brain (2011) 134:678-92. doi:10.1093/brain/awq386
-
(2011)
Brain
, vol.134
, pp. 678-692
-
-
Linker, R.A.1
Lee, D.-H.2
Ryan, S.3
van Dam, A.M.4
Conrad, R.5
Bista, P.6
-
245
-
-
77952301752
-
Dimethylfumarate inhibits microglial and astrocytic inflammation by suppressing the synthesis of nitric oxide, IL-1beta, TNF-alpha and IL-6 in an in-vitro model of brain inflammation
-
Wilms H, Sievers J, Rickert U, Rostami-Yazdi M, Mrowietz U, Lucius R. Dimethylfumarate inhibits microglial and astrocytic inflammation by suppressing the synthesis of nitric oxide, IL-1beta, TNF-alpha and IL-6 in an in-vitro model of brain inflammation. J Neuroinflammation (2010) 7:30. doi:10.1186/1742-2094-7-30
-
(2010)
J Neuroinflammation
, vol.7
, pp. 30
-
-
Wilms, H.1
Sievers, J.2
Rickert, U.3
Rostami-Yazdi, M.4
Mrowietz, U.5
Lucius, R.6
-
246
-
-
84855603512
-
Cellular and molecular mechanisms of metformin: an overview
-
Viollet B, Guigas B, Sanz Garcia N, Leclerc J, Foretz M, Andreelli F. Cellular and molecular mechanisms of metformin: an overview. Clin Sci (2012) 122:253-70. doi:10.1042/CS20110386
-
(2012)
Clin Sci
, vol.122
, pp. 253-270
-
-
Viollet, B.1
Guigas, B.2
Sanz Garcia, N.3
Leclerc, J.4
Foretz, M.5
Andreelli, F.6
-
247
-
-
84939625498
-
Metformin inhibits the production of reactive oxygen species from NADH:Ubiquinone oxidoreductase to limit induction of interleukin-1β (IL-1β) and boosts interleukin-10 (IL-10) in lipopolysaccharide (LPS)-activated macrophages
-
Kelly B, Tannahill GM, Murphy MP, O'Neill LAJ. Metformin inhibits the production of reactive oxygen species from NADH:Ubiquinone oxidoreductase to limit induction of interleukin-1β (IL-1β) and boosts interleukin-10 (IL-10) in lipopolysaccharide (LPS)-activated macrophages. J Biol Chem (2015) 290:20348-59. doi:10.1074/jbc.M115.662114
-
(2015)
J Biol Chem
, vol.290
, pp. 20348-20359
-
-
Kelly, B.1
Tannahill, G.M.2
Murphy, M.P.3
O'Neill, L.A.J.4
-
248
-
-
67649196932
-
Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis
-
Nath N, Khan M, Paintlia MK, Singh I, Hoda MN, Giri S. Metformin attenuated the autoimmune disease of the central nervous system in animal models of multiple sclerosis. J Immunol (2009) 182:8005-14. doi:10.4049/jimmunol.0803563
-
(2009)
J Immunol
, vol.182
, pp. 8005-8014
-
-
Nath, N.1
Khan, M.2
Paintlia, M.K.3
Singh, I.4
Hoda, M.N.5
Giri, S.6
-
249
-
-
84960926090
-
Metformin ameliorates the development of experimental autoimmune encephalomyelitis by regulating T helper 17 and regulatory T cells in mice
-
Sun Y, Tian T, Gao J, Liu X, Hou H, Cao R, et al. Metformin ameliorates the development of experimental autoimmune encephalomyelitis by regulating T helper 17 and regulatory T cells in mice. J Neuroimmunol (2016) 292:58-67. doi:10.1016/j.jneuroim.2016.01.014
-
(2016)
J Neuroimmunol
, vol.292
, pp. 58-67
-
-
Sun, Y.1
Tian, T.2
Gao, J.3
Liu, X.4
Hou, H.5
Cao, R.6
-
250
-
-
84966570157
-
Immunologic effects of metformin and pioglitazone treatment on metabolic syndrome and multiple sclerosis
-
Negrotto L, Farez MF, Correale J. Immunologic effects of metformin and pioglitazone treatment on metabolic syndrome and multiple sclerosis. JAMA Neurol (2016) 73:520-8. doi:10.1001/jamaneurol.2015.4807
-
(2016)
JAMA Neurol
, vol.73
, pp. 520-528
-
-
Negrotto, L.1
Farez, M.F.2
Correale, J.3
-
251
-
-
84966691974
-
Positive effect on multiple sclerosis with treatment of metabolic syndrome
-
Haghikia A, Gold R. Positive effect on multiple sclerosis with treatment of metabolic syndrome. JAMA Neurol (2016) 73:499-501. doi:10.1001/jamaneurol.2015.5050
-
(2016)
JAMA Neurol
, vol.73
, pp. 499-501
-
-
Haghikia, A.1
Gold, R.2
-
252
-
-
84959236568
-
Pioglitazone
-
Al-Majed A, Bakheit AHH, Abdel Aziz HA, Alharbi H, Al-Jenoobi FI. Pioglitazone. Profiles Drug Subst Excip Relat Methodol (2016) 41:379-438. doi:10.1016/bs.podrm.2015.11.002
-
(2016)
Profiles Drug Subst Excip Relat Methodol
, vol.41
, pp. 379-438
-
-
Al-Majed, A.1
Bakheit, A.H.H.2
Abdel Aziz, H.A.3
Alharbi, H.4
Al-Jenoobi, F.I.5
-
253
-
-
0036260784
-
Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis
-
Feinstein DL, Galea E, Gavrilyuk V, Brosnan CF, Whitacre CC, Dumitrescu-Ozimek L, et al. Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis. Ann Neurol (2002) 51:694-702. doi:10.1002/ana.10206
-
(2002)
Ann Neurol
, vol.51
, pp. 694-702
-
-
Feinstein, D.L.1
Galea, E.2
Gavrilyuk, V.3
Brosnan, C.F.4
Whitacre, C.C.5
Dumitrescu-Ozimek, L.6
-
254
-
-
14844282813
-
Peroxisome proliferator-activated receptor-gamma agonists inhibit the activation of microglia and astrocytes: implications for multiple sclerosis
-
Storer PD, Xu J, Chavis J, Drew PD. Peroxisome proliferator-activated receptor-gamma agonists inhibit the activation of microglia and astrocytes: implications for multiple sclerosis. J Neuroimmunol (2005) 161:113-22. doi:10.1016/j.jneuroim.2004.12.015
-
(2005)
J Neuroimmunol
, vol.161
, pp. 113-122
-
-
Storer, P.D.1
Xu, J.2
Chavis, J.3
Drew, P.D.4
|