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Volumn 13, Issue 6, 2013, Pages 427-437

Regulation of innate and adaptive immunity by Notch

Author keywords

[No Author keywords available]

Indexed keywords

NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; NOTCH4 RECEPTOR;

EID: 84878245626     PISSN: 14741733     EISSN: 14741741     Source Type: Journal    
DOI: 10.1038/nri3445     Document Type: Review
Times cited : (325)

References (119)
  • 1
    • 0000674913 scopus 로고
    • The theory of the gene
    • Morgan, T. H. The theory of the gene. Am. Nat. 51, 513-544 (1917).
    • (1917) Am. Nat. , vol.51 , pp. 513-544
    • Morgan, T.H.1
  • 2
    • 33747623018 scopus 로고    scopus 로고
    • Notch signalling: A simple pathway becomes complex
    • Bray, S. J. Notch signalling: a simple pathway becomes complex. Nature Rev. Mol. Cell Biol. 7, 678-689 (2006).
    • (2006) Nature Rev. Mol. Cell Biol. , vol.7 , pp. 678-689
    • Bray, S.J.1
  • 3
    • 64249172203 scopus 로고    scopus 로고
    • The canonical Notch signaling pathway: Unfolding the activation mechanism
    • Kopan, R. & Ilagan, M. X. G. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 137, 216-233 (2009).
    • (2009) Cell , vol.137 , pp. 216-233
    • Kopan, R.1    Ilagan, M.X.G.2
  • 4
    • 56049092014 scopus 로고    scopus 로고
    • Modulating Notch signaling by pathway-intrinsic and pathway-extrinsic mechanisms
    • Poellinger, L. & Lendahl, U. Modulating Notch signaling by pathway-intrinsic and pathway-extrinsic mechanisms. Curr. Opin. Genet. Dev. 18, 449-454 (2008).
    • (2008) Curr. Opin. Genet. Dev. , vol.18 , pp. 449-454
    • Poellinger, L.1    Lendahl, U.2
  • 5
    • 52649179291 scopus 로고    scopus 로고
    • Notch1 and TGFβ1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells
    • Samon, J. B. et al. Notch1 and TGFβ1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. Blood 112, 1813-1821 (2008).
    • (2008) Blood , vol.112 , pp. 1813-1821
    • Samon, J.B.1
  • 6
    • 77956328365 scopus 로고    scopus 로고
    • Biodiversity and noncanonical Notch signaling
    • Heitzler, P. Biodiversity and noncanonical Notch signaling. Curr. Top. Dev. Biol. 92, 457-481 (2010).
    • (2010) Curr. Top. Dev. Biol. , vol.92 , pp. 457-481
    • Heitzler, P.1
  • 7
    • 33845306813 scopus 로고    scopus 로고
    • NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth
    • Palomero, T. et al. NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth. Proc. Natl Acad. Sci. USA 103, 18261-18266 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 18261-18266
    • Palomero, T.1
  • 8
    • 33746546368 scopus 로고    scopus 로고
    • C-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma
    • Weng, A. P. et al. c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma. Genes Dev. 20, 2096-2109 (2006).
    • (2006) Genes Dev. , vol.20 , pp. 2096-2109
    • Weng, A.P.1
  • 9
    • 0037363922 scopus 로고    scopus 로고
    • HES and HERP families: Multiple effectors of the Notch signaling pathway
    • Iso, T., Kedes, L. & Hamamori, Y. HES and HERP families: multiple effectors of the Notch signaling pathway. J. Cell. Physiol. 194, 237-255 (2003).
    • (2003) J. Cell. Physiol. , vol.194 , pp. 237-255
    • Iso, T.1    Kedes, L.2    Hamamori, Y.3
  • 10
    • 0033136717 scopus 로고    scopus 로고
    • Deficient T cell fate specification in mice with an induced inactivation of Notch1
    • Radtke, F. et al. Deficient T cell fate specification in mice with an induced inactivation of Notch1. Immunity 10, 547-558 (1999).
    • (1999) Immunity , vol.10 , pp. 547-558
    • Radtke, F.1
  • 11
    • 0035988246 scopus 로고    scopus 로고
    • Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision
    • Han, H. et al. Inducible gene knockout of transcription factor recombination signal binding protein-J reveals its essential role in T versus B lineage decision. Int. Immunol. 14, 637-645 (2002).
    • (2002) Int. Immunol. , vol.14 , pp. 637-645
    • Han, H.1
  • 12
    • 20244389684 scopus 로고    scopus 로고
    • Notch1 expression in early lymphopoiesis influences B versus T lineage determination
    • Pui, J. C. et al. Notch1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity 11, 299-308 (1999).
    • (1999) Immunity , vol.11 , pp. 299-308
    • Pui, J.C.1
  • 13
    • 0034869258 scopus 로고    scopus 로고
    • Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1
    • Koch, U. et al. Subversion of the T/B lineage decision in the thymus by lunatic fringe-mediated inhibition of Notch-1. Immunity 15, 225-236 (2001).
    • (2001) Immunity , vol.15 , pp. 225-236
    • Koch, U.1
  • 14
    • 18344388633 scopus 로고    scopus 로고
    • Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1
    • Izon, D. J. et al. Deltex1 redirects lymphoid progenitors to the B cell lineage by antagonizing Notch1. Immunity 16, 231-243 (2002).
    • (2002) Immunity , vol.16 , pp. 231-243
    • Izon, D.J.1
  • 15
    • 0037606092 scopus 로고    scopus 로고
    • Notch-regulated ankyrin-repeat protein inhibits Notch1 signaling: Multiple Notch1 signaling pathways involved in T cell development
    • Yun, T. J. & Bevan, M. J. Notch-regulated ankyrin-repeat protein inhibits Notch1 signaling: multiple Notch1 signaling pathways involved in T cell development. J. Immunol. 170, 5834-5841 (2003).
    • (2003) J. Immunol. , vol.170 , pp. 5834-5841
    • Yun, T.J.1    Bevan, M.J.2
  • 16
    • 4444328365 scopus 로고    scopus 로고
    • Mastermind critically regulates Notch-mediated lymphoid cell fate decisions
    • Maillard, I. et al. Mastermind critically regulates Notch-mediated lymphoid cell fate decisions. Blood 104, 1696-1702 (2004).
    • (2004) Blood , vol.104 , pp. 1696-1702
    • Maillard, I.1
  • 17
    • 0035477668 scopus 로고    scopus 로고
    • Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus
    • Wilson, A., MacDonald, H. R. & Radtke, F. Notch 1-deficient common lymphoid precursors adopt a B cell fate in the thymus. J. Exp. Med. 194, 1003-1012 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 1003-1012
    • Wilson, A.1    MacDonald, H.R.2    Radtke, F.3
  • 18
    • 42049087865 scopus 로고    scopus 로고
    • The earliest thymic progenitors for T cells possess myeloid lineage potential
    • Bell, J. J. & Bhandoola, A. The earliest thymic progenitors for T cells possess myeloid lineage potential. Nature 452, 764-767 (2008).
    • (2008) Nature , vol.452 , pp. 764-767
    • Bell, J.J.1    Bhandoola, A.2
  • 19
    • 42049089318 scopus 로고    scopus 로고
    • Adult T-cell progenitors retain myeloid potential
    • Wada, H. et al. Adult T-cell progenitors retain myeloid potential. Nature 452, 768-772 (2008).
    • (2008) Nature , vol.452 , pp. 768-772
    • Wada, H.1
  • 20
    • 58149251919 scopus 로고    scopus 로고
    • Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms
    • Feyerabend, T. B. et al. Deletion of Notch1 converts pro-T cells to dendritic cells and promotes thymic B cells by cell-extrinsic and cell-intrinsic mechanisms. Immunity 30, 67-79 (2009).
    • (2009) Immunity , vol.30 , pp. 67-79
    • Feyerabend, T.B.1
  • 21
    • 78649363017 scopus 로고    scopus 로고
    • Hes1 is a critical but context-dependent mediator of canonical Notch signaling in lymphocyte development and transformation
    • Wendorff, A. A. et al. Hes1 is a critical but context-dependent mediator of canonical Notch signaling in lymphocyte development and transformation. Immunity 33, 671-684 (2010).
    • (2010) Immunity , vol.33 , pp. 671-684
    • Wendorff, A.A.1
  • 22
    • 0035476891 scopus 로고    scopus 로고
    • Differential effects of Notch ligands 5-1 and Jagged-1 in human lymphoid differentiation
    • Jaleco, A. C. et al. Differential effects of Notch ligands 5-1 and Jagged-1 in human lymphoid differentiation. J. Exp. Med. 194, 991-1002 (2001).
    • (2001) J. Exp. Med. , vol.194 , pp. 991-1002
    • Jaleco, A.C.1
  • 23
    • 0036916440 scopus 로고    scopus 로고
    • Induction of T cell development from hematopoietic progenitor cells by δ-like-1 in vitro
    • Schmitt, T. M. & Zuniga-Pflucker, J. C. Induction of T cell development from hematopoietic progenitor cells by δ-like-1 in vitro. Immunity 17, 749-756 (2002).
    • (2002) Immunity , vol.17 , pp. 749-756
    • Schmitt, T.M.1    Zuniga-Pflucker, J.C.2
  • 24
    • 58149154746 scopus 로고    scopus 로고
    • δ-like 4 is indispensable in thymic environment specific for T cell development
    • Hozumi, K. et al. δ-like 4 is indispensable in thymic environment specific for T cell development. J. Exp. Med. 205, 2507-2513 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 2507-2513
    • Hozumi, K.1
  • 25
    • 58149151302 scopus 로고    scopus 로고
    • δ-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment
    • Koch, U. et al. δ-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment. J. Exp. Med. 205, 2515-2523 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 2515-2523
    • Koch, U.1
  • 26
    • 77955496968 scopus 로고    scopus 로고
    • Direct comparison of Dll1-and Dll4-mediated Notch activation levels shows differential lymphomyeloid lineage commitment outcomes
    • Mohtashami, M. et al. Direct comparison of Dll1-and Dll4-mediated Notch activation levels shows differential lymphomyeloid lineage commitment outcomes. J. Immunol. 185, 867-876 (2010).
    • (2010) J. Immunol. , vol.185 , pp. 867-876
    • Mohtashami, M.1
  • 27
    • 30444454357 scopus 로고    scopus 로고
    • Developmental and molecular characterization of emerging β-and yô-selected pre-T cells in the adult mouse thymus
    • Taghon, T., Yui, M. A., Pant, R., Diamond, R. A. & Rothenberg, E. V. Developmental and molecular characterization of emerging β-and yô-selected pre-T cells in the adult mouse thymus. Immunity 24, 53-64 (2006).
    • (2006) Immunity , vol.24 , pp. 53-64
    • Taghon, T.1    Yui, M.A.2    Pant, R.3    Diamond, R.A.4    Rothenberg, E.V.5
  • 28
    • 63849086285 scopus 로고    scopus 로고
    • An early decrease in Notch activation is required for human TCR-aβ lineage differentiation at the expense of TCR-yδ T cells
    • Van de Walle, I. et al. An early decrease in Notch activation is required for human TCR-aβ lineage differentiation at the expense of TCR-yδ T cells. Blood 113, 2988-2998 (2009).
    • (2009) Blood , vol.113 , pp. 2988-2998
    • Van De Walle, I.1
  • 29
    • 65349103035 scopus 로고    scopus 로고
    • Notch signaling is required for proliferation but not for differentiation at a well-defined β-selection checkpoint during human T-cell development
    • Taghon, T. et al. Notch signaling is required for proliferation but not for differentiation at a well-defined β-selection checkpoint during human T-cell development. Blood 113, 3254-3263 (2009).
    • (2009) Blood , vol.113 , pp. 3254-3263
    • Taghon, T.1
  • 30
    • 67650588402 scopus 로고    scopus 로고
    • Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A
    • Yashiro-Ohtani, Y. et al. Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A. Genes Dev. 23, 1665-1676 (2009).
    • (2009) Genes Dev. , vol.23 , pp. 1665-1676
    • Yashiro-Ohtani, Y.1
  • 31
    • 70350515662 scopus 로고    scopus 로고
    • The follicular versus marginal zone B lymphocyte cell fate decision
    • Pillai, S. & Cariappa, A. The follicular versus marginal zone B lymphocyte cell fate decision. Nature Rev. Immunol. 9, 767-777 (2009).
    • (2009) Nature Rev. Immunol. , vol.9 , pp. 767-777
    • Pillai, S.1    Cariappa, A.2
  • 32
    • 0036754302 scopus 로고    scopus 로고
    • Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses
    • Balazs, M., Martin, F., Zhou, T. & Kearney, J. Blood dendritic cells interact with splenic marginal zone B cells to initiate T-independent immune responses. Immunity 17, 341-352 (2002).
    • (2002) Immunity , vol.17 , pp. 341-352
    • Balazs, M.1    Martin, F.2    Zhou, T.3    Kearney, J.4
  • 33
    • 2942659675 scopus 로고    scopus 로고
    • δ-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo
    • Hozumi, K. et al. δ-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo. Nature Immunol. 5, 638-644 (2004).
    • (2004) Nature Immunol. , vol.5 , pp. 638-644
    • Hozumi, K.1
  • 34
    • 0038742790 scopus 로고    scopus 로고
    • Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development
    • Saito, T. et al. Notch2 is preferentially expressed in mature B cells and indispensable for marginal zone B lineage development. Immunity 18, 675-685 (2003).
    • (2003) Immunity , vol.18 , pp. 675-685
    • Saito, T.1
  • 35
    • 0036094254 scopus 로고    scopus 로고
    • Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells
    • Tanigaki, K. et al. Notch-RBP-J signaling is involved in cell fate determination of marginal zone B cells. Nature Immunol. 3, 443-450 (2002).
    • (2002) Nature Immunol. , vol.3 , pp. 443-450
    • Tanigaki, K.1
  • 36
    • 34547447032 scopus 로고    scopus 로고
    • Mastermind-1 is required for Notch signal-dependent steps in lymphocyte development in vivo
    • Oyama, T. et al. Mastermind-1 is required for Notch signal-dependent steps in lymphocyte development in vivo. Proc. Natl Acad. Sci. USA 104, 9764-9769 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 9764-9769
    • Oyama, T.1
  • 37
    • 36348966669 scopus 로고    scopus 로고
    • The transcriptional coactivator Maml1 is required for Notch2-mediated marginal zone B-cell development
    • Wu, L., Maillard, I., Nakamura, M., Pear, W. S. & Griffin, J. D. The transcriptional coactivator Maml1 is required for Notch2-mediated marginal zone B-cell development. Blood 110, 3618-3623 (2007).
    • (2007) Blood , vol.110 , pp. 3618-3623
    • Wu, L.1    Maillard, I.2    Nakamura, M.3    Pear, W.S.4    Griffin, J.D.5
  • 38
    • 58149143044 scopus 로고    scopus 로고
    • Mind bomb 1 in the lymphopoietic niches is essential for T and marginal zone B cell development
    • Song, R. et al. Mind bomb 1 in the lymphopoietic niches is essential for T and marginal zone B cell development. J. Exp. Med. 205, 2525-2536 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 2525-2536
    • Song, R.1
  • 39
    • 77949528417 scopus 로고    scopus 로고
    • ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo
    • Gibb, D. R. et al. ADAM10 is essential for Notch2-dependent marginal zone B cell development and CD23 cleavage in vivo. J. Exp. Med. 207, 623-635 (2010).
    • (2010) J. Exp. Med. , vol.207 , pp. 623-635
    • Gibb, D.R.1
  • 40
    • 0037332254 scopus 로고    scopus 로고
    • Regulation of marginal zone B cell development by MINT, a suppressor of Notch/RBP-J signaling pathway
    • Kuroda, K. et al. Regulation of marginal zone B cell development by MINT, a suppressor of Notch/RBP-J signaling pathway. Immunity 18, 301-312 (2003).
    • (2003) Immunity , vol.18 , pp. 301-312
    • Kuroda, K.1
  • 41
    • 60149102638 scopus 로고    scopus 로고
    • Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for δ-like 1 in splenic endothelial niches
    • Tan, J. et al. Lunatic and manic fringe cooperatively enhance marginal zone B cell precursor competition for δ-like 1 in splenic endothelial niches. Immunity 30, 254-263 (2009).
    • (2009) Immunity , vol.30 , pp. 254-263
    • Tan, J.1
  • 42
    • 34447275920 scopus 로고    scopus 로고
    • Notch-RBP-J signaling controls the homeostasis of CD8-dendritic cells in the spleen
    • Caton, M. L., Smith-Raska, M. R. & Reizis, B. Notch-RBP-J signaling controls the homeostasis of CD8-dendritic cells in the spleen. J. Exp. Med. 204, 1653-1664 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 1653-1664
    • Caton, M.L.1    Smith-Raska, M.R.2    Reizis, B.3
  • 43
    • 81955164775 scopus 로고    scopus 로고
    • Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine
    • Lewis, K. L. et al. Notch2 receptor signaling controls functional differentiation of dendritic cells in the spleen and intestine. Immunity 35, 780-791 (2011).
    • (2011) Immunity , vol.35 , pp. 780-791
    • Lewis, K.L.1
  • 44
    • 0034599854 scopus 로고    scopus 로고
    • Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells
    • Radtke, F. et al. Notch1 deficiency dissociates the intrathymic development of dendritic cells and T cells. J. Exp. Med. 191, 1085-1094 (2000).
    • (2000) J. Exp. Med. , vol.191 , pp. 1085-1094
    • Radtke, F.1
  • 45
    • 0037108556 scopus 로고    scopus 로고
    • + plasmacytoid dendritic cells develop independently of the T-cell lineage
    • + plasmacytoid dendritic cells develop independently of the T-cell lineage. Blood 100, 2852-2857 (2002).
    • (2002) Blood , vol.100 , pp. 2852-2857
    • Ferrero, I.1
  • 46
    • 84859384082 scopus 로고    scopus 로고
    • Innate lymphoid cells: Emerging insights in development, lineage relationships, and function
    • Spits, H. & Cupedo, T. Innate lymphoid cells: emerging insights in development, lineage relationships, and function. Annu. Rev. Immunol. 30, 647-675 (2012).
    • (2012) Annu. Rev. Immunol. , vol.30 , pp. 647-675
    • Spits, H.1    Cupedo, T.2
  • 47
    • 84872977452 scopus 로고    scopus 로고
    • Innate lymphoid cells-a proposal for uniform nomenclature
    • Spits, H. et al. Innate lymphoid cells-a proposal for uniform nomenclature. Nature Rev. Immunol. 13, 145-149 (2013).
    • (2013) Nature Rev. Immunol. , vol.13 , pp. 145-149
    • Spits, H.1
  • 48
    • 78650310810 scopus 로고    scopus 로고
    • The expanding family of innate lymphoid cells: Regulators and effectors of immunity and tissue remodeling
    • Spits, H. & Di Santo, J. P. The expanding family of innate lymphoid cells: regulators and effectors of immunity and tissue remodeling. Nature Immunol. 12, 21-27 (2011).
    • (2011) Nature Immunol. , vol.12 , pp. 21-27
    • Spits, H.1    Di Santo, J.P.2
  • 49
    • 84861722864 scopus 로고    scopus 로고
    • Id2, and RORγt sequentially orchestrate the fetal development of lymphoid tissue inducer cells
    • Cherrier, M., Sawa, S. & Eberl, G. Notch, Id2, and RORγt sequentially orchestrate the fetal development of lymphoid tissue inducer cells. J. Exp. Med. 209, 729-740 (2012).
    • (2012) J. Exp. Med. , vol.209 , pp. 729-740
    • Cherrier, M.1    Sawa, S.2    Notch, E.G.3
  • 50
    • 57449118239 scopus 로고    scopus 로고
    • + cells that provide innate mucosal immune defense
    • + cells that provide innate mucosal immune defense. Immunity 29, 958-970 (2008).
    • (2008) Immunity , vol.29 , pp. 958-970
    • Satoh-Takayama, N.1
  • 51
    • 40049083827 scopus 로고    scopus 로고
    • Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens
    • Zheng, Y. et al. Interleukin-22 mediates early host defense against attaching and effacing bacterial pathogens. Nature Med. 14, 282-289 (2008).
    • (2008) Nature Med. , vol.14 , pp. 282-289
    • Zheng, Y.1
  • 52
    • 83855160821 scopus 로고    scopus 로고
    • Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles
    • Kiss, E. A. et al. Natural aryl hydrocarbon receptor ligands control organogenesis of intestinal lymphoid follicles. Science 334, 1561-1565 (2011).
    • (2011) Science , vol.334 , pp. 1561-1565
    • Kiss, E.A.1
  • 53
    • 80155164160 scopus 로고    scopus 로고
    • Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation
    • Li, Y. et al. Exogenous stimuli maintain intraepithelial lymphocytes via aryl hydrocarbon receptor activation. Cell 147, 629-640 (2011).
    • (2011) Cell , vol.147 , pp. 629-640
    • Li, Y.1
  • 54
    • 84855917402 scopus 로고    scopus 로고
    • AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch
    • Lee, J. S. et al. AHR drives the development of gut ILC22 cells and postnatal lymphoid tissues via pathways dependent on and independent of Notch. Nature Immunol. 13, 144-151 (2012).
    • (2012) Nature Immunol. , vol.13 , pp. 144-151
    • Lee, J.S.1
  • 55
    • 77951878587 scopus 로고    scopus 로고
    • Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology
    • Buonocore, S. et al. Innate lymphoid cells drive interleukin-23-dependent innate intestinal pathology Nature 464, 1371-1375 (2010).
    • (2010) Nature , vol.464 , pp. 1371-1375
    • Buonocore, S.1
  • 56
    • 77951817855 scopus 로고    scopus 로고
    • Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
    • Neill, D. R. et al. Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature 464, 1367-1370 (2010).
    • (2010) Nature , vol.464 , pp. 1367-1370
    • Neill, D.R.1
  • 57
    • 77954926597 scopus 로고    scopus 로고
    • Systemically dispersed innate IL-13-expressing cells in type 2 immunity
    • Price, A. E. et al. Systemically dispersed innate IL-13-expressing cells in type 2 immunity. Proc. Natl Acad. Sci. USA 107, 11489-11494 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 11489-11494
    • Price, A.E.1
  • 58
    • 84863393407 scopus 로고    scopus 로고
    • Transcription factor RORa is critical for nuocyte development
    • Wong, S. H. et al. Transcription factor RORa is critical for nuocyte development. Nature Immunol. 13, 229-236 (2012).
    • (2012) Nature Immunol. , vol.13 , pp. 229-236
    • Wong, S.H.1
  • 59
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann, T. R., Cherwinski, H., Bond, M. W., Giedlin, M. A. & Coffman, R. L. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol. 136, 2348-2357 (1986).
    • (1986) J. Immunol. , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 60
    • 27544490377 scopus 로고    scopus 로고
    • + effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • + effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nature Immunol. 6, 1123-1132 (2005).
    • (2005) Nature Immunol. , vol.6 , pp. 1123-1132
    • Harrington, L.E.1
  • 61
    • 32244442562 scopus 로고    scopus 로고
    • TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
    • Veldhoen, M., Hocking, R. J., Atkins, C. J., Locksley, R. M. & Stockinger, B. TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 24, 179-189 (2006).
    • (2006) Immunity , vol.24 , pp. 179-189
    • Veldhoen, M.1    Hocking, R.J.2    Atkins, C.J.3    Locksley, R.M.4    Stockinger, B.5
  • 62
    • 0348223787 scopus 로고    scopus 로고
    • + regulatory T cells by TGF-β induction of transcription factor Foxp3
    • + regulatory T cells by TGF-β induction of transcription factor Foxp3. J. Exp. Med. 198, 1875-1886 (2003).
    • (2003) J. Exp. Med. , vol.198 , pp. 1875-1886
    • Chen, W.1
  • 63
    • 56349154943 scopus 로고    scopus 로고
    • Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
    • Veldhoen, M. et al. Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nature Immunol. 9, 1341-1346 (2008).
    • (2008) Nature Immunol. , vol.9 , pp. 1341-1346
    • Veldhoen, M.1
  • 64
    • 56349093347 scopus 로고    scopus 로고
    • + Foxp3-effector T cells
    • + Foxp3-effector T cells. Nature Immunol. 9, 1347-1355 (2008).
    • (2008) Nature Immunol. , vol.9 , pp. 1347-1355
    • Dardalhon, V.1
  • 65
    • 69249109601 scopus 로고    scopus 로고
    • Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation
    • Johnston, R. J. et al. Bcl6 and Blimp-1 are reciprocal and antagonistic regulators of T follicular helper cell differentiation. Science 325, 1006-1010 (2009).
    • (2009) Science , vol.325 , pp. 1006-1010
    • Johnston, R.J.1
  • 66
    • 69249101229 scopus 로고    scopus 로고
    • Bcl6 mediates the development of T follicular helper cells
    • Nurieva, R. I. et al. Bcl6 mediates the development of T follicular helper cells. Science 325, 1001-1005 (2009).
    • (2009) Science , vol.325 , pp. 1001-1005
    • Nurieva, R.I.1
  • 70
    • 74549176827 scopus 로고    scopus 로고
    • Notch signaling in the immune system
    • Radtke, F., Fasnacht, N. & Macdonald, H. R. Notch signaling in the immune system. Immunity 32, 14-27 (2010).
    • (2010) Immunity , vol.32 , pp. 14-27
    • Radtke, F.1    Fasnacht, N.2    MacDonald, H.R.3
  • 72
    • 2342496710 scopus 로고    scopus 로고
    • Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells
    • Amsen, D. et al. Instruction of distinct CD4 T helper cell fates by different notch ligands on antigen-presenting cells. Cell 117, 515-526 (2004).
    • (2004) Cell , vol.117 , pp. 515-526
    • Amsen, D.1
  • 73
    • 58849099058 scopus 로고    scopus 로고
    • The different faces of Notch in T-helper-cell differentiation
    • Amsen, D., Antov, A. & Flavell, R. A. The different faces of Notch in T-helper-cell differentiation. Nature Rev. Immunol. 9, 116-124 (2009).
    • (2009) Nature Rev. Immunol. , vol.9 , pp. 116-124
    • Amsen, D.1    Antov, A.2    Flavell, R.A.3
  • 74
    • 22144492615 scopus 로고    scopus 로고
    • Inhibitors of y-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21
    • Minter, L. M. et al. Inhibitors of y-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21. Nature Immunol. 6, 680-688 (2005).
    • (2005) Nature Immunol. , vol.6 , pp. 680-688
    • Minter, L.M.1
  • 75
    • 42149177242 scopus 로고    scopus 로고
    • Notch3 inhibition in myelin-reactive T cells down-regulates protein kinase C theta and attenuates experimental autoimmune encephalomyelitis
    • Jurynczyk, M., Jurewicz, A., Raine, C. S. & Selmaj, K. Notch3 inhibition in myelin-reactive T cells down-regulates protein kinase C theta and attenuates experimental autoimmune encephalomyelitis. J. Immunol. 180, 2634-2640 (2008).
    • (2008) J. Immunol. , vol.180 , pp. 2634-2640
    • Jurynczyk, M.1    Jurewicz, A.2    Raine, C.S.3    Selmaj, K.4
  • 76
    • 34447642439 scopus 로고    scopus 로고
    • Notch directly regulates Gata3 expression during T helper 2 cell differentiation
    • Fang, T. C. et al. Notch directly regulates Gata3 expression during T helper 2 cell differentiation. Immunity 27, 100-110 (2007).
    • (2007) Immunity , vol.27 , pp. 100-110
    • Fang, T.C.1
  • 77
    • 26844538164 scopus 로고    scopus 로고
    • Notch signaling is an important regulator of type 2 immunity
    • Tu, L. et al. Notch signaling is an important regulator of type 2 immunity. J. Exp. Med. 202, 1037-1042 (2005).
    • (2005) J. Exp. Med. , vol.202 , pp. 1037-1042
    • Tu, L.1
  • 78
    • 84863598267 scopus 로고    scopus 로고
    • Redundant Notch1 and Notch2 signaling is necessary for IFNy secretion by T helper 1 cells during infection with Leishmania major
    • Auderset, F et al. Redundant Notch1 and Notch2 signaling is necessary for IFNy secretion by T helper 1 cells during infection with Leishmania major. PLoS Pathog. 8, e1002560 (2012).
    • (2012) PLoS Pathog. , vol.8
    • Auderset, F.1
  • 79
    • 0041331708 scopus 로고    scopus 로고
    • TCR-mediated notch signaling regulates proliferation and IFN-y production in peripheral T cells
    • Palaga, T, Miele, L, Golde, T. E. & Osborne, B. A. TCR-mediated notch signaling regulates proliferation and IFN-y production in peripheral T cells. J. Immunol. 171, 3019-3024 (2003).
    • (2003) J. Immunol. , vol.171 , pp. 3019-3024
    • Palaga, T.1    Miele, L.2    Golde, T.E.3    Osborne, B.A.4
  • 80
    • 30444450802 scopus 로고    scopus 로고
    • Notch1 augments NF-KB activity by facilitating its nuclear retention
    • Shin, H. M. et al. Notch1 augments NF-KB activity by facilitating its nuclear retention. EMBO J. 25, 129-138 (2006).
    • (2006) EMBO J. , vol.25 , pp. 129-138
    • Shin, H.M.1
  • 81
    • 34447634411 scopus 로고    scopus 로고
    • Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch
    • Amsen, D. et al. Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity 27, 89-99 (2007).
    • (2007) Immunity , vol.27 , pp. 89-99
    • Amsen, D.1
  • 82
    • 33745081482 scopus 로고    scopus 로고
    • The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells
    • Tanaka, S. et al. The interleukin-4 enhancer CNS-2 is regulated by Notch signals and controls initial expression in NKT cells and memory-type CD4 T cells. Immunity 24, 689-701 (2006).
    • (2006) Immunity , vol.24 , pp. 689-701
    • Tanaka, S.1
  • 83
    • 0030810155 scopus 로고    scopus 로고
    • The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
    • Zheng, W & Flavell, R. A. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 89, 587-596 (1997).
    • (1997) Cell , vol.89 , pp. 587-596
    • Zheng, W.1    Flavell, R.A.2
  • 84
    • 84859997488 scopus 로고    scopus 로고
    • Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells
    • Elyaman, W et al. Notch receptors and Smad3 signaling cooperate in the induction of interleukin-9-producing T cells. Immunity 36, 623-634 (2012).
    • (2012) Immunity , vol.36 , pp. 623-634
    • Elyaman, W.1
  • 85
    • 82955228112 scopus 로고    scopus 로고
    • H17 cytokines in autoimmune neuro-inflammation
    • H17 cytokines in autoimmune neuro-inflammation. Curr. Opin. Immunol. 23, 707-712 (2011).
    • (2011) Curr. Opin. Immunol. , vol.23 , pp. 707-712
    • Becher, B.1    Segal, B.M.2
  • 87
    • 10744222828 scopus 로고    scopus 로고
    • Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes
    • Anastasi, E. et al. Expression of activated Notch3 in transgenic mice enhances generation of T regulatory cells and protects against experimental autoimmune diabetes. J. Immunol. 171, 4504-4511 (2003).
    • (2003) J. Immunol. , vol.171 , pp. 4504-4511
    • Anastasi, E.1
  • 88
    • 66249108256 scopus 로고    scopus 로고
    • Notch3 and pTa/pre-TCR sustain the in vivo function of naturally occurring regulatory T cells
    • Campese, A. F et al. Notch3 and pTa/pre-TCR sustain the in vivo function of naturally occurring regulatory T cells. Int. Immunol. 21, 727-743 (2009).
    • (2009) Int. Immunol. , vol.21 , pp. 727-743
    • Campese, A.F.1
  • 89
    • 79958058411 scopus 로고    scopus 로고
    • Notch3 and canonical NF-KB signaling pathways cooperatively regulate Foxp3 transcription
    • Barbarulo, A. et al. Notch3 and canonical NF-KB signaling pathways cooperatively regulate Foxp3 transcription. J. Immunol. 186, 6199-6206 (2011).
    • (2011) J. Immunol. , vol.186 , pp. 6199-6206
    • Barbarulo, A.1
  • 90
    • 33846250032 scopus 로고    scopus 로고
    • Jagged2-expressing hematopoietic progenitors promote regulatory T cell expansion in the periphery through notch signaling
    • Kared, H. et al. Jagged2-expressing hematopoietic progenitors promote regulatory T cell expansion in the periphery through notch signaling. Immunity 25, 823-834 (2006).
    • (2006) Immunity , vol.25 , pp. 823-834
    • Kared, H.1
  • 91
    • 80052685578 scopus 로고    scopus 로고
    • Notch ligand δ-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development
    • Bassil, R. et al. Notch ligand δ-like 4 blockade alleviates experimental autoimmune encephalomyelitis by promoting regulatory T cell development. J. Immunol. 187, 2322-2328 (2011).
    • (2011) J. Immunol. , vol.187 , pp. 2322-2328
    • Bassil, R.1
  • 92
    • 38449102218 scopus 로고    scopus 로고
    • JAGGED1 and δ1 differentially regulate the outcome of experimental autoimmune encephalomyelitis
    • Elyaman, W et al. JAGGED1 and δ1 differentially regulate the outcome of experimental autoimmune encephalomyelitis. J. Immunol. 179, 5990-5998 (2007).
    • (2007) J. Immunol. , vol.179 , pp. 5990-5998
    • Elyaman, W.1
  • 93
    • 84863794078 scopus 로고    scopus 로고
    • Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice
    • Billiard, F et al. Dll4-Notch signaling in Flt3-independent dendritic cell development and autoimmunity in mice. J. Exp. Med. 209, 1011-1028 (2012).
    • (2012) J. Exp. Med. , vol.209 , pp. 1011-1028
    • Billiard, F.1
  • 94
    • 12444279957 scopus 로고    scopus 로고
    • Differentiation and expansion of T cells with regulatory function from human peripheral lymphocytes by stimulation in the presence of TGF-β
    • Rao, P. E., Petrone, A. L. & Ponath, P. D. Differentiation and expansion of T cells with regulatory function from human peripheral lymphocytes by stimulation in the presence of TGF-β. J. Immunol. 174, 1446-1455 (2005).
    • (2005) J. Immunol. , vol.174 , pp. 1446-1455
    • Rao, P.E.1    Petrone, A.L.2    Ponath, P.D.3
  • 96
    • 0141566334 scopus 로고    scopus 로고
    • Induction of antigen-specific regulatory T cells following overexpression of a Notch ligand by human B lymphocytes
    • Vigouroux, S. et al. Induction of antigen-specific regulatory T cells following overexpression of a Notch ligand by human B lymphocytes. J. Virol. 77, 10872-10880 (2003).
    • (2003) J. Virol. , vol.77 , pp. 10872-10880
    • Vigouroux, S.1
  • 98
    • 84872498240 scopus 로고    scopus 로고
    • Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction
    • Del Papa, B. et al. Notch1 modulates mesenchymal stem cells mediated regulatory T-cell induction. Eur. J. Immunol. 43, 182-187 (2012).
    • (2012) Eur. J. Immunol. , vol.43 , pp. 182-187
    • Del Papa, B.1
  • 99
    • 84864125056 scopus 로고    scopus 로고
    • Programming of regulatory T cells from pluripotent stem cells and prevention of autoimmunity
    • Haque, R. et al. Programming of regulatory T cells from pluripotent stem cells and prevention of autoimmunity. J. Immunol. 189, 1228-1236 (2012).
    • (2012) J. Immunol. , vol.189 , pp. 1228-1236
    • Haque, R.1
  • 100
    • 0347951391 scopus 로고    scopus 로고
    • + cell-dependent mechanism
    • + cell-dependent mechanism. J. Clin. Invest. 112, 1741-1750 (2003).
    • (2003) J. Clin. Invest. , vol.112 , pp. 1741-1750
    • Wong, K.1
  • 101
    • 52549130987 scopus 로고    scopus 로고
    • Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity
    • Maekawa, Y et al. Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity. Nature Immunol. 9, 1140-1147 (2008).
    • (2008) Nature Immunol. , vol.9 , pp. 1140-1147
    • Maekawa, Y.1
  • 102
    • 80555149831 scopus 로고    scopus 로고
    • Blockade of Notch ligand δ1 promotes allograft survival by inhibiting alloreactive Th1 cells and cytotoxic T cell generation
    • Riella, L. V et al. Blockade of Notch ligand δ1 promotes allograft survival by inhibiting alloreactive Th1 cells and cytotoxic T cell generation. J. Immunol. 187, 4629-4638 (2011).
    • (2011) J. Immunol. , vol.187 , pp. 4629-4638
    • Riella, L.V.1
  • 103
    • 77954507341 scopus 로고    scopus 로고
    • Notch2 signaling is required for potent antitumor immunity in vivo
    • Sugimoto, K. et al. Notch2 signaling is required for potent antitumor immunity in vivo. J. Immunol. 184, 4673-4678 (2010).
    • (2010) J. Immunol. , vol.184 , pp. 4673-4678
    • Sugimoto, K.1
  • 104
    • 65449183749 scopus 로고    scopus 로고
    • + T cells
    • + T cells. J. Immunol. 182, 3380-3389 (2009).
    • (2009) J. Immunol. , vol.182 , pp. 3380-3389
    • Cho, O.H.1
  • 105
    • 84878264534 scopus 로고    scopus 로고
    • + T cells
    • + T cells. Blood 121, 2638-2646 (2013).
    • (2013) Blood , vol.121 , pp. 2638-2646
    • Kuijk, L.M.1
  • 106
    • 34247867901 scopus 로고    scopus 로고
    • Immunobiology of allogeneic hematopoietic stem cell transplantation
    • Welniak, L. A., Blazar, B. R. & Murphy, W J. Immunobiology of allogeneic hematopoietic stem cell transplantation. Annu. Rev. Immunol. 25, 139-170 (2007).
    • (2007) Annu. Rev. Immunol. , vol.25 , pp. 139-170
    • Welniak, L.A.1    Blazar, B.R.2    Murphy, W.J.3
  • 107
    • 78650996522 scopus 로고    scopus 로고
    • + T-cell responses mediating graft-versus-host disease
    • + T-cell responses mediating graft-versus-host disease. Blood 117, 299-308 (2011).
    • (2011) Blood , vol.117 , pp. 299-308
    • Zhang, Y.1
  • 108
    • 84875837518 scopus 로고    scopus 로고
    • Blockade of individual Notch ligands and receptors controls graft-versus-host disease
    • Tran, I. T. et al. Blockade of individual Notch ligands and receptors controls graft-versus-host disease. J. Clin. Invest. 123, 1590-1604 (2013).
    • (2013) J. Clin. Invest. , vol.123 , pp. 1590-1604
    • Tran, I.T.1
  • 109
    • 79960111924 scopus 로고    scopus 로고
    • Ikaros-Notch axis in host hematopoietic cells regulates experimental graft-versus-host disease
    • Toubai, T. et al. Ikaros-Notch axis in host hematopoietic cells regulates experimental graft-versus-host disease. Blood 118, 192-204 (2011).
    • (2011) Blood , vol.118 , pp. 192-204
    • Toubai, T.1
  • 110
    • 33645227683 scopus 로고    scopus 로고
    • Notch activation is an early and critical event during T-cell leukemogenesis in Ikaros-deficient mice
    • Dumortier, A. et al. Notch activation is an early and critical event during T-cell leukemogenesis in Ikaros-deficient mice. Mol. Cell. Biol. 26, 209-220 (2006).
    • (2006) Mol. Cell. Biol. , vol.26 , pp. 209-220
    • Dumortier, A.1
  • 111
    • 78650213618 scopus 로고    scopus 로고
    • Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis
    • Gomez-del Arco, P. et al. Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis. Immunity 33, 685-698 (2010).
    • (2010) Immunity , vol.33 , pp. 685-698
    • Gomez-Del Arco, P.1
  • 112
    • 0035168209 scopus 로고    scopus 로고
    • Y-secretase inhibitors as molecular probes of presenilin function
    • Wolfe, M. S. y-secretase inhibitors as molecular probes of presenilin function. J. Mol. Neurosci. 17, 199-204 (2001).
    • (2001) J. Mol. Neurosci. , vol.17 , pp. 199-204
    • Wolfe, M.S.1
  • 113
    • 0037137482 scopus 로고    scopus 로고
    • Modulation of receptor signaling by glycosylation: Fringe is an O-fucose-β 1, 3-N-acetylglucosaminyltransferase
    • Haltiwanger, R. S. & Stanley, P. Modulation of receptor signaling by glycosylation: fringe is an O-fucose-β 1, 3-N- acetylglucosaminyltransferase. Biochim. Biophys. Acta 1573, 328-335 (2002).
    • (2002) Biochim. Biophys. Acta , vol.1573 , pp. 328-335
    • Haltiwanger, R.S.1    Stanley, P.2
  • 114
    • 0242593940 scopus 로고    scopus 로고
    • Glycosyltransferase activity of Fringe modulates Notch-0 interactions
    • Bruckner, K., Perez, L, Clausen, H. & Cohen, S. Glycosyltransferase activity of Fringe modulates Notch-0 interactions. Nature 406, 411-415 (2000).
    • (2000) Nature , vol.406 , pp. 411-415
    • Bruckner, K.1    Perez, L.2    Clausen, H.3    Cohen, S.4
  • 115
    • 12944255642 scopus 로고    scopus 로고
    • Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by 51 and Jagged1
    • Yang, L. T. et al. Fringe glycosyltransferases differentially modulate Notch1 proteolysis induced by 51 and Jagged1. Mol. Biol. Cell 16, 927-942 (2005).
    • (2005) Mol. Biol. Cell , vol.16 , pp. 927-942
    • Yang, L.T.1
  • 116
    • 33847103659 scopus 로고    scopus 로고
    • Hierarchy of Notch-0 interactions promoting T cell lineage commitment and maturation
    • Besseyrias, V et al. Hierarchy of Notch-0 interactions promoting T cell lineage commitment and maturation. J. Exp. Med. 204, 331-343 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 331-343
    • Besseyrias, V.1
  • 117
    • 35549010987 scopus 로고    scopus 로고
    • The origin and application of experimental autoimmune encephalomyelitis
    • Baxter, A. G. The origin and application of experimental autoimmune encephalomyelitis. Nature Rev. Immunol. 7, 904-912 (2007).
    • (2007) Nature Rev. Immunol. , vol.7 , pp. 904-912
    • Baxter, A.G.1
  • 118
    • 77956107505 scopus 로고    scopus 로고
    • Ameliorating effects of anti-Dll4 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease
    • Takeichi, N. et al. Ameliorating effects of anti-Dll4 mAb on Theiler's murine encephalomyelitis virus-induced demyelinating disease. Int. Immunol. 22, 729-738 (2010).
    • (2010) Int. Immunol. , vol.22 , pp. 729-738
    • Takeichi, N.1
  • 119
    • 80052655552 scopus 로고    scopus 로고
    • δ-like ligand 4 regulates central nervous system T cell accumulation during experimental autoimmune encephalomyelitis
    • Reynolds, N. D., Lukacs, N. W., Long, N. & Karpus, W J. δ-like ligand 4 regulates central nervous system T cell accumulation during experimental autoimmune encephalomyelitis. J. Immunol. 187, 2803-2813 (2011).
    • (2011) J. Immunol. , vol.187 , pp. 2803-2813
    • Reynolds, N.D.1    Lukacs, N.W.2    Long, N.3    Karpus, W.J.4


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