-
1
-
-
78649819162
-
αv Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice
-
Acharya M., Mukhopadhyay S., Païdassi H., Jamil T., Chow C., Kissler S., Stuart L.M., Hynes R.O., Lacy-Hulbert A. αv Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice. J.Clin. Invest. 2010, 120:4445-4452.
-
(2010)
J.Clin. Invest.
, vol.120
, pp. 4445-4452
-
-
Acharya, M.1
Mukhopadhyay, S.2
Païdassi, H.3
Jamil, T.4
Chow, C.5
Kissler, S.6
Stuart, L.M.7
Hynes, R.O.8
Lacy-Hulbert, A.9
-
2
-
-
77950534540
-
T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis
-
Axtell R.C., de Jong B.A., Boniface K., van der Voort L.F., Bhat R., De Sarno P., Naves R., Han M., Zhong F., Castellanos J.G., et al. T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis. Nat. Med. 2010, 16:406-412.
-
(2010)
Nat. Med.
, vol.16
, pp. 406-412
-
-
Axtell, R.C.1
de Jong, B.A.2
Boniface, K.3
van der Voort, L.F.4
Bhat, R.5
De Sarno, P.6
Naves, R.7
Han, M.8
Zhong, F.9
Castellanos, J.G.10
-
3
-
-
33747588291
-
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing Tcells
-
Batten M., Li J., Yi S., Kljavin N.M., Danilenko D.M., Lucas S., Lee J., de Sauvage F.J., Ghilardi N. Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing Tcells. Nat. Immunol. 2006, 7:929-936.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 929-936
-
-
Batten, M.1
Li, J.2
Yi, S.3
Kljavin, N.M.4
Danilenko, D.M.5
Lucas, S.6
Lee, J.7
de Sauvage, F.J.8
Ghilardi, N.9
-
4
-
-
0347357773
-
IL-23 produced by CNS-resident cells controls Tcell encephalitogenicity during the effector phase of experimental autoimmune encephalomyelitis
-
Becher B., Durell B.G., Noelle R.J. IL-23 produced by CNS-resident cells controls Tcell encephalitogenicity during the effector phase of experimental autoimmune encephalomyelitis. J.Clin. Invest. 2003, 112:1186-1191.
-
(2003)
J.Clin. Invest.
, vol.112
, pp. 1186-1191
-
-
Becher, B.1
Durell, B.G.2
Noelle, R.J.3
-
5
-
-
84887058596
-
Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis
-
International Multiple Sclerosis Genetics Consortium (IMSGC), Wellcome Trust Case Control Consortium 2 (WTCCC2)Wellcome Trust Case Control Consortium 2 (WTCCC2), International IBD Genetics Consortium (IIBDGC)International IBD Genetics Consortium (IIBDGC)
-
Beecham A.H., Patsopoulos N.A., Xifara D.K., Davis M.F., Kemppinen A., Cotsapas C., Shah T.S., Spencer C., Booth D., Goris A., et al. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat. Genet. 2013, 45:1353-1360. International Multiple Sclerosis Genetics Consortium (IMSGC), Wellcome Trust Case Control Consortium 2 (WTCCC2)Wellcome Trust Case Control Consortium 2 (WTCCC2), International IBD Genetics Consortium (IIBDGC)International IBD Genetics Consortium (IIBDGC).
-
(2013)
Nat. Genet.
, vol.45
, pp. 1353-1360
-
-
Beecham, A.H.1
Patsopoulos, N.A.2
Xifara, D.K.3
Davis, M.F.4
Kemppinen, A.5
Cotsapas, C.6
Shah, T.S.7
Spencer, C.8
Booth, D.9
Goris, A.10
-
6
-
-
33646577466
-
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory Tcells
-
Bettelli E., Carrier Y., Gao W., Korn T., Strom T.B., Oukka M., Weiner H.L., Kuchroo V.K. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory Tcells. Nature 2006, 441:235-238.
-
(2006)
Nature
, vol.441
, pp. 235-238
-
-
Bettelli, E.1
Carrier, Y.2
Gao, W.3
Korn, T.4
Strom, T.B.5
Oukka, M.6
Weiner, H.L.7
Kuchroo, V.K.8
-
7
-
-
84866565809
-
The small ubiquitin-like modifier-deconjugating enzyme sentrin-specific peptidase 1 switches IFN regulatory factor 8 from a repressor to an activator during macrophage activation
-
Chang T.H., Xu S., Tailor P., Kanno T., Ozato K. The small ubiquitin-like modifier-deconjugating enzyme sentrin-specific peptidase 1 switches IFN regulatory factor 8 from a repressor to an activator during macrophage activation. J.Immunol. 2012, 189:3548-3556.
-
(2012)
J.Immunol.
, vol.189
, pp. 3548-3556
-
-
Chang, T.H.1
Xu, S.2
Tailor, P.3
Kanno, T.4
Ozato, K.5
-
8
-
-
33646433989
-
Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis
-
Chen Y., Langrish C.L., McKenzie B., Joyce-Shaikh B., Stumhofer J.S., McClanahan T., Blumenschein W., Churakovsa T., Low J., Presta L., et al. Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. J.Clin. Invest. 2006, 116:1317-1326.
-
(2006)
J.Clin. Invest.
, vol.116
, pp. 1317-1326
-
-
Chen, Y.1
Langrish, C.L.2
McKenzie, B.3
Joyce-Shaikh, B.4
Stumhofer, J.S.5
McClanahan, T.6
Blumenschein, W.7
Churakovsa, T.8
Low, J.9
Presta, L.10
-
9
-
-
0033177995
-
Conditional gene targeting in macrophages and granulocytes using LysMcre mice
-
Clausen B.E., Burkhardt C., Reith W., Renkawitz R., Förster I. Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res. 1999, 8:265-277.
-
(1999)
Transgenic Res.
, vol.8
, pp. 265-277
-
-
Clausen, B.E.1
Burkhardt, C.2
Reith, W.3
Renkawitz, R.4
Förster, I.5
-
10
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
Cua D.J., Sherlock J., Chen Y., Murphy C.A., Joyce B., Seymour B., Lucian L., To W., Kwan S., Churakova T., et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 2003, 421:744-748.
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
Murphy, C.A.4
Joyce, B.5
Seymour, B.6
Lucian, L.7
To, W.8
Kwan, S.9
Churakova, T.10
-
11
-
-
67649876123
-
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
-
International MS Genetics Consortium
-
De Jager P.L., Jia X., Wang J., de Bakker P.I.W., Ottoboni L., Aggarwal N.T., Piccio L., Raychaudhuri S., Tran D., Aubin C., et al. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci. Nat. Genet. 2009, 41:776-782. International MS Genetics Consortium.
-
(2009)
Nat. Genet.
, vol.41
, pp. 776-782
-
-
De Jager, P.L.1
Jia, X.2
Wang, J.3
de Bakker, P.I.W.4
Ottoboni, L.5
Aggarwal, N.T.6
Piccio, L.7
Raychaudhuri, S.8
Tran, D.9
Aubin, C.10
-
12
-
-
84857744447
-
Genomic regions associated with multiple sclerosis are active in B cells
-
Disanto G., Sandve G.K., Berlanga-Taylor A.J., Morahan J.M., Dobson R., Giovannoni G., Ramagopalan S.V. Genomic regions associated with multiple sclerosis are active in B cells. PLoS ONE 2012, 7:e32281.
-
(2012)
PLoS ONE
, vol.7
-
-
Disanto, G.1
Sandve, G.K.2
Berlanga-Taylor, A.J.3
Morahan, J.M.4
Dobson, R.5
Giovannoni, G.6
Ramagopalan, S.V.7
-
13
-
-
79251561555
-
IFN regulatory factor 8 restricts the size of the marginal zone and follicular B cell pools
-
Feng J., Wang H., Shin D.M., Masiuk M., Qi C.F., Morse H.C. IFN regulatory factor 8 restricts the size of the marginal zone and follicular B cell pools. J.Immunol. 2011, 186:1458-1466.
-
(2011)
J.Immunol.
, vol.186
, pp. 1458-1466
-
-
Feng, J.1
Wang, H.2
Shin, D.M.3
Masiuk, M.4
Qi, C.F.5
Morse, H.C.6
-
14
-
-
79960219807
-
IRF8 Mutations and Human Dendritic-Cell Immunodeficiency
-
Hambleton S., Salem S., Bustamante J., Bigley V., Boisson-Dupuis S., Azevedo J., Fortin A., Haniffa M., Ceron-Gutierrez L., Bacon C.M., et al. IRF8 Mutations and Human Dendritic-Cell Immunodeficiency. N Engl J Med 2011.
-
(2011)
N Engl J Med
-
-
Hambleton, S.1
Salem, S.2
Bustamante, J.3
Bigley, V.4
Boisson-Dupuis, S.5
Azevedo, J.6
Fortin, A.7
Haniffa, M.8
Ceron-Gutierrez, L.9
Bacon, C.M.10
-
15
-
-
33749059726
-
The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration
-
Hauser S.L., Oksenberg J.R. The neurobiology of multiple sclerosis: genes, inflammation, and neurodegeneration. Neuron 2006, 52:61-76.
-
(2006)
Neuron
, vol.52
, pp. 61-76
-
-
Hauser, S.L.1
Oksenberg, J.R.2
-
16
-
-
84877025203
-
Integrin-mediated regulation of TGFβ in fibrosis
-
Henderson N.C., Sheppard D. Integrin-mediated regulation of TGFβ in fibrosis. Biochim. Biophys. Acta 2013, 1832:891-896.
-
(2013)
Biochim. Biophys. Acta
, vol.1832
, pp. 891-896
-
-
Henderson, N.C.1
Sheppard, D.2
-
17
-
-
84866673725
-
Interferon regulatory factor 8/interferon consensus sequence binding protein is a critical transcription factor for the physiological phenotype of microglia
-
Horiuchi M., Wakayama K., Itoh A., Kawai K., Pleasure D., Ozato K., Itoh T. Interferon regulatory factor 8/interferon consensus sequence binding protein is a critical transcription factor for the physiological phenotype of microglia. J.Neuroinflammation 2012, 9:227.
-
(2012)
J.Neuroinflammation
, vol.9
, pp. 227
-
-
Horiuchi, M.1
Wakayama, K.2
Itoh, A.3
Kawai, K.4
Pleasure, D.5
Ozato, K.6
Itoh, T.7
-
18
-
-
33748588423
-
The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells
-
Ivanov I.I., McKenzie B.S., Zhou L., Tadokoro C.E., Lepelley A., Lafaille J.J., Cua D.J., Littman D.R. The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cells. Cell 2006, 126:1121-1133.
-
(2006)
Cell
, vol.126
, pp. 1121-1133
-
-
Ivanov, I.I.1
McKenzie, B.S.2
Zhou, L.3
Tadokoro, C.E.4
Lepelley, A.5
Lafaille, J.J.6
Cua, D.J.7
Littman, D.R.8
-
19
-
-
58149280443
-
Lymph-migrating, tissue-derived dendritic cells are minor constituents within steady-state lymph nodes
-
Jakubzick C., Bogunovic M., Bonito A.J., Kuan E.L., Merad M., Randolph G.J. Lymph-migrating, tissue-derived dendritic cells are minor constituents within steady-state lymph nodes. J.Exp. Med. 2008, 205:2839-2850.
-
(2008)
J.Exp. Med.
, vol.205
, pp. 2839-2850
-
-
Jakubzick, C.1
Bogunovic, M.2
Bonito, A.J.3
Kuan, E.L.4
Merad, M.5
Randolph, G.J.6
-
20
-
-
33745321276
-
IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis
-
Komiyama Y., Nakae S., Matsuki T., Nambu A., Ishigame H., Kakuta S., Sudo K., Iwakura Y. IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. J.Immunol. 2006, 177:566-573.
-
(2006)
J.Immunol.
, vol.177
, pp. 566-573
-
-
Komiyama, Y.1
Nakae, S.2
Matsuki, T.3
Nambu, A.4
Ishigame, H.5
Kakuta, S.6
Sudo, K.7
Iwakura, Y.8
-
21
-
-
46949104323
-
IL-12- and IL-23-modulated Tcells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition
-
Kroenke M.A., Carlson T.J., Andjelkovic A.V., Segal B.M. IL-12- and IL-23-modulated Tcells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition. J.Exp. Med. 2008, 205:1535-1541.
-
(2008)
J.Exp. Med.
, vol.205
, pp. 1535-1541
-
-
Kroenke, M.A.1
Carlson, T.J.2
Andjelkovic, A.V.3
Segal, B.M.4
-
22
-
-
84876493933
-
Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation
-
Kurotaki D., Osato N., Nishiyama A., Yamamoto M., Ban T., Sato H., Nakabayashi J., Umehara M., Miyake N., Matsumoto N., et al. Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation. Blood 2013, 121:1839-1849.
-
(2013)
Blood
, vol.121
, pp. 1839-1849
-
-
Kurotaki, D.1
Osato, N.2
Nishiyama, A.3
Yamamoto, M.4
Ban, T.5
Sato, H.6
Nakabayashi, J.7
Umehara, M.8
Miyake, N.9
Matsumoto, N.10
-
23
-
-
26444490607
-
Partner-regulated interaction of IFN regulatory factor 8 with chromatin visualized in live macrophages
-
Laricchia-Robbio L., Tamura T., Karpova T., Sprague B.L., McNally J.G., Ozato K. Partner-regulated interaction of IFN regulatory factor 8 with chromatin visualized in live macrophages. Proc. Natl. Acad. Sci. USA 2005, 102:14368-14373.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 14368-14373
-
-
Laricchia-Robbio, L.1
Tamura, T.2
Karpova, T.3
Sprague, B.L.4
McNally, J.G.5
Ozato, K.6
-
24
-
-
33846593869
-
Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia
-
Li Y., Chu N., Hu A., Gran B., Rostami A., Zhang G.-X. Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia. Brain 2007, 130:490-501.
-
(2007)
Brain
, vol.130
, pp. 490-501
-
-
Li, Y.1
Chu, N.2
Hu, A.3
Gran, B.4
Rostami, A.5
Zhang, G.-X.6
-
25
-
-
78650178184
-
Th1 versus Th17: are Tcell cytokines relevant in multiple sclerosis?
-
Lovett-Racke A.E., Yang Y., Racke M.K. Th1 versus Th17: are Tcell cytokines relevant in multiple sclerosis?. Biochim. Biophys. Acta 2011, 1812:246-251.
-
(2011)
Biochim. Biophys. Acta
, vol.1812
, pp. 246-251
-
-
Lovett-Racke, A.E.1
Yang, Y.2
Racke, M.K.3
-
26
-
-
77956546075
-
SMAD2 is essential for TGF beta-mediated Th17 cell generation
-
Malhotra N., Robertson E., Kang J. SMAD2 is essential for TGF beta-mediated Th17 cell generation. J.Biol. Chem. 2010, 285:29044-29048.
-
(2010)
J.Biol. Chem.
, vol.285
, pp. 29044-29048
-
-
Malhotra, N.1
Robertson, E.2
Kang, J.3
-
27
-
-
84861123981
-
IRF8 is a critical transcription factor for transforming microglia into a reactive phenotype
-
Masuda T., Tsuda M., Yoshinaga R., Tozaki-Saitoh H., Ozato K., Tamura T., Inoue K. IRF8 is a critical transcription factor for transforming microglia into a reactive phenotype. Cell Rep 2012, 1:334-340.
-
(2012)
Cell Rep
, vol.1
, pp. 334-340
-
-
Masuda, T.1
Tsuda, M.2
Yoshinaga, R.3
Tozaki-Saitoh, H.4
Ozato, K.5
Tamura, T.6
Inoue, K.7
-
28
-
-
78649807601
-
Expression of αvβ8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice
-
Melton A.C., Bailey-Bucktrout S.L., Travis M.A., Fife B.T., Bluestone J.A., Sheppard D. Expression of αvβ8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice. J.Clin. Invest. 2010, 120:4436-4444.
-
(2010)
J.Clin. Invest.
, vol.120
, pp. 4436-4444
-
-
Melton, A.C.1
Bailey-Bucktrout, S.L.2
Travis, M.A.3
Fife, B.T.4
Bluestone, J.A.5
Sheppard, D.6
-
29
-
-
84875950146
-
IFN regulatory factor 8 is a key constitutive determinant of the morphological and molecular properties of microglia in the CNS
-
Minten C., Terry R., Deffrasnes C., King N.J., Campbell I.L. IFN regulatory factor 8 is a key constitutive determinant of the morphological and molecular properties of microglia in the CNS. PLoS ONE 2012, 7:e49851.
-
(2012)
PLoS ONE
, vol.7
-
-
Minten, C.1
Terry, R.2
Deffrasnes, C.3
King, N.J.4
Campbell, I.L.5
-
30
-
-
84864355786
-
Interferon regulatory factor 8 integrates T-cell receptor and cytokine-signaling pathways and drives effector differentiation of CD8 Tcells
-
Miyagawa F., Zhang H., Terunuma A., Ozato K., Tagaya Y., Katz S.I. Interferon regulatory factor 8 integrates T-cell receptor and cytokine-signaling pathways and drives effector differentiation of CD8 Tcells. Proc. Natl. Acad. Sci. USA 2012, 109:12123-12128.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 12123-12128
-
-
Miyagawa, F.1
Zhang, H.2
Terunuma, A.3
Ozato, K.4
Tagaya, Y.5
Katz, S.I.6
-
31
-
-
79956279442
-
Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation
-
Ouyang X., Zhang R., Yang J., Li Q., Qin L., Zhu C., Liu J., Ning H., Shin M.S., Gupta M., et al. Transcription factor IRF8 directs a silencing programme for TH17 cell differentiation. Nat Commun 2011, 2:314.
-
(2011)
Nat Commun
, vol.2
, pp. 314
-
-
Ouyang, X.1
Zhang, R.2
Yang, J.3
Li, Q.4
Qin, L.5
Zhu, C.6
Liu, J.7
Ning, H.8
Shin, M.S.9
Gupta, M.10
-
32
-
-
79952769679
-
+) regulatory Tcells promote Th17 cells invitro and enhance host resistance in mouse Candida albicans Th17 cell infection model
-
+) regulatory Tcells promote Th17 cells invitro and enhance host resistance in mouse Candida albicans Th17 cell infection model. Immunity 2011, 34:422-434.
-
(2011)
Immunity
, vol.34
, pp. 422-434
-
-
Pandiyan, P.1
Conti, H.R.2
Zheng, L.3
Peterson, A.C.4
Mathern, D.R.5
Hernández-Santos, N.6
Edgerton, M.7
Gaffen, S.L.8
Lenardo, M.J.9
-
33
-
-
27544465354
-
A distinct lineage of CD4 Tcells regulates tissue inflammation by producing interleukin 17
-
Park H., Li Z., Yang X.O., Chang S.H., Nurieva R., Wang Y.H., Wang Y., Hood L., Zhu Z., Tian Q., Dong C. A distinct lineage of CD4 Tcells regulates tissue inflammation by producing interleukin 17. Nat. Immunol. 2005, 6:1133-1141.
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.H.6
Wang, Y.7
Hood, L.8
Zhu, Z.9
Tian, Q.10
Dong, C.11
-
34
-
-
34547928758
-
Magnetic resonance imaging of blood-spinal cord barrier disruption in mice with experimental autoimmune encephalomyelitis
-
Schellenberg A.E., Buist R., Yong V.W., Del Bigio M.R., Peeling J. Magnetic resonance imaging of blood-spinal cord barrier disruption in mice with experimental autoimmune encephalomyelitis. Magn. Reson. Med. 2007, 58:298-305.
-
(2007)
Magn. Reson. Med.
, vol.58
, pp. 298-305
-
-
Schellenberg, A.E.1
Buist, R.2
Yong, V.W.3
Del Bigio, M.R.4
Peeling, J.5
-
35
-
-
78751690657
-
Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity
-
Shaw P.J., Barr M.J., Lukens J.R., McGargill M.A., Chi H., Mak T.W., Kanneganti T.D. Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity. Immunity 2011, 34:75-84.
-
(2011)
Immunity
, vol.34
, pp. 75-84
-
-
Shaw, P.J.1
Barr, M.J.2
Lukens, J.R.3
McGargill, M.A.4
Chi, H.5
Mak, T.W.6
Kanneganti, T.D.7
-
36
-
-
0033559346
-
Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients
-
Sørensen T.L., Tani M., Jensen J., Pierce V., Lucchinetti C., Folcik V.A., Qin S., Rottman J., Sellebjerg F., Strieter R.M., et al. Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients. J.Clin. Invest. 1999, 103:807-815.
-
(1999)
J.Clin. Invest.
, vol.103
, pp. 807-815
-
-
Sørensen, T.L.1
Tani, M.2
Jensen, J.3
Pierce, V.4
Lucchinetti, C.5
Folcik, V.A.6
Qin, S.7
Rottman, J.8
Sellebjerg, F.9
Strieter, R.M.10
-
37
-
-
84865351085
-
Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration
-
Starossom S.C., Mascanfroni I.D., Imitola J., Cao L., Raddassi K., Hernandez S.F., Bassil R., Croci D.O., Cerliani J.P., Delacour D., et al. Galectin-1 deactivates classically activated microglia and protects from inflammation-induced neurodegeneration. Immunity 2012, 37:249-263.
-
(2012)
Immunity
, vol.37
, pp. 249-263
-
-
Starossom, S.C.1
Mascanfroni, I.D.2
Imitola, J.3
Cao, L.4
Raddassi, K.5
Hernandez, S.F.6
Bassil, R.7
Croci, D.O.8
Cerliani, J.P.9
Delacour, D.10
-
38
-
-
33745728404
-
How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis
-
Steinman L., Zamvil S.S. How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis. Ann. Neurol. 2006, 60:12-21.
-
(2006)
Ann. Neurol.
, vol.60
, pp. 12-21
-
-
Steinman, L.1
Zamvil, S.S.2
-
39
-
-
40449089827
-
Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells
-
Stromnes I.M., Cerretti L.M., Liggitt D., Harris R.A., Goverman J.M. Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells. Nat. Med. 2008, 14:337-342.
-
(2008)
Nat. Med.
, vol.14
, pp. 337-342
-
-
Stromnes, I.M.1
Cerretti, L.M.2
Liggitt, D.3
Harris, R.A.4
Goverman, J.M.5
-
40
-
-
33747593830
-
Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system
-
Stumhofer J.S., Laurence A., Wilson E.H., Huang E., Tato C.M., Johnson L.M., Villarino A.V., Huang Q., Yoshimura A., Sehy D., et al. Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nat. Immunol. 2006, 7:937-945.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 937-945
-
-
Stumhofer, J.S.1
Laurence, A.2
Wilson, E.H.3
Huang, E.4
Tato, C.M.5
Johnson, L.M.6
Villarino, A.V.7
Huang, Q.8
Yoshimura, A.9
Sehy, D.10
-
41
-
-
0031048823
-
Reduced incidence and severity of antigen-induced autoimmune diseases in mice lacking interferon regulatory factor-1
-
Tada Y., Ho A., Matsuyama T., Mak T.W. Reduced incidence and severity of antigen-induced autoimmune diseases in mice lacking interferon regulatory factor-1. J.Exp. Med. 1997, 185:231-238.
-
(1997)
J.Exp. Med.
, vol.185
, pp. 231-238
-
-
Tada, Y.1
Ho, A.2
Matsuyama, T.3
Mak, T.W.4
-
42
-
-
41349119601
-
The BXH2 mutation in IRF8 differentially impairs dendritic cell subset development in the mouse
-
Tailor P., Tamura T., Morse H.C., Ozato K. The BXH2 mutation in IRF8 differentially impairs dendritic cell subset development in the mouse. Blood 2008, 111:1942-1945.
-
(2008)
Blood
, vol.111
, pp. 1942-1945
-
-
Tailor, P.1
Tamura, T.2
Morse, H.C.3
Ozato, K.4
-
43
-
-
14044270784
-
IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity
-
Tamura T., Tailor P., Yamaoka K., Kong H.J., Tsujimura H., O'Shea J.J., Singh H., Ozato K. IFN regulatory factor-4 and -8 govern dendritic cell subset development and their functional diversity. J.Immunol. 2005, 174:2573-2581.
-
(2005)
J.Immunol.
, vol.174
, pp. 2573-2581
-
-
Tamura, T.1
Tailor, P.2
Yamaoka, K.3
Kong, H.J.4
Tsujimura, H.5
O'Shea, J.J.6
Singh, H.7
Ozato, K.8
-
44
-
-
34548208943
-
Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice
-
Travis M.A., Reizis B., Melton A.C., Masteller E., Tang Q., Proctor J.M., Wang Y., Bernstein X., Huang X., Reichardt L.F., et al. Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice. Nature 2007, 449:361-365.
-
(2007)
Nature
, vol.449
, pp. 361-365
-
-
Travis, M.A.1
Reizis, B.2
Melton, A.C.3
Masteller, E.4
Tang, Q.5
Proctor, J.M.6
Wang, Y.7
Bernstein, X.8
Huang, X.9
Reichardt, L.F.10
-
45
-
-
33750142276
-
Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease
-
Veldhoen M., Hocking R.J., Flavell R.A., Stockinger B. Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease. Nat. Immunol. 2006, 7:1151-1156.
-
(2006)
Nat. Immunol.
, vol.7
, pp. 1151-1156
-
-
Veldhoen, M.1
Hocking, R.J.2
Flavell, R.A.3
Stockinger, B.4
-
46
-
-
84864124859
-
IL-12 family cytokines: immunological playmakers
-
Vignali D.A., Kuchroo V.K. IL-12 family cytokines: immunological playmakers. Nat. Immunol. 2012, 13:722-728.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 722-728
-
-
Vignali, D.A.1
Kuchroo, V.K.2
-
47
-
-
33847206969
-
IL-17 family cytokines and the expanding diversity of effector Tcell lineages
-
Weaver C.T., Hatton R.D., Mangan P.R., Harrington L.E. IL-17 family cytokines and the expanding diversity of effector Tcell lineages. Annu. Rev. Immunol. 2007, 25:821-852.
-
(2007)
Annu. Rev. Immunol.
, vol.25
, pp. 821-852
-
-
Weaver, C.T.1
Hatton, R.D.2
Mangan, P.R.3
Harrington, L.E.4
-
48
-
-
37849048599
-
T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma
-
Yang X.O., Pappu B.P., Nurieva R., Akimzhanov A., Kang H.S., Chung Y., Ma L., Shah B., Panopoulos A.D., Schluns K.S., et al. T helper 17 lineage differentiation is programmed by orphan nuclear receptors ROR alpha and ROR gamma. Immunity 2008, 28:29-39.
-
(2008)
Immunity
, vol.28
, pp. 29-39
-
-
Yang, X.O.1
Pappu, B.P.2
Nurieva, R.3
Akimzhanov, A.4
Kang, H.S.5
Chung, Y.6
Ma, L.7
Shah, B.8
Panopoulos, A.D.9
Schluns, K.S.10
-
49
-
-
77954359269
-
Activation of IL-27 p28 gene transcription by interferon regulatory factor 8 in cooperation with interferon regulatory factor 1
-
Zhang J., Qian X., Ning H., Yang J., Xiong H., Liu J. Activation of IL-27 p28 gene transcription by interferon regulatory factor 8 in cooperation with interferon regulatory factor 1. J.Biol. Chem. 2010, 285:21269-21281.
-
(2010)
J.Biol. Chem.
, vol.285
, pp. 21269-21281
-
-
Zhang, J.1
Qian, X.2
Ning, H.3
Yang, J.4
Xiong, H.5
Liu, J.6
|