메뉴 건너뛰기




Volumn 8, Issue 11, 2013, Pages

Integrated expression profiles of mRNA and miRNA in polarized primary murine microglia

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI LIPOPOLYSACCHARIDE; INTERLEUKIN 4; MESSENGER RNA; MICRORNA; MICRORNA 124; MICRORNA 145; MICRORNA 155; MICRORNA 689; MICRORNA 711; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; STAT3 PROTEIN; UNCLASSIFIED DRUG; LIPOPOLYSACCHARIDE; TRANSCRIPTOME;

EID: 84893202052     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079416     Document Type: Article
Times cited : (138)

References (84)
  • 1
    • 84863446652 scopus 로고    scopus 로고
    • Noninvasive molecular imaging of neuroinflammation
    • Jacobs AH, Tavitian B (2012) Noninvasive molecular imaging of neuroinflammation. J Cereb Blood Flow Metab 32: 1393-1415.
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 1393-1415
    • Jacobs, A.H.1    Tavitian, B.2
  • 2
    • 47949099098 scopus 로고    scopus 로고
    • Origin and physiological roles of inflammation
    • Medzhitov R (2008) Origin and physiological roles of inflammation. Nature 454: 428-435.
    • (2008) Nature , vol.454 , pp. 428-435
    • Medzhitov, R.1
  • 3
    • 79251648284 scopus 로고    scopus 로고
    • Neuroimmune pharmacology as a sub-discipline of medical neuroscience in the medical school curriculum
    • Freilich RW, Ikezu T (2011) Neuroimmune pharmacology as a sub-discipline of medical neuroscience in the medical school curriculum. J Neuroimmune Pharmacol 6: 41-56.
    • (2011) J Neuroimmune Pharmacol , vol.6 , pp. 41-56
    • Freilich, R.W.1    Ikezu, T.2
  • 4
    • 77951837763 scopus 로고    scopus 로고
    • Trafficking of immune cells in the central nervous system
    • Wilson EH, Weninger W, Hunter CA (2010) Trafficking of immune cells in the central nervous system. J Clin Invest 120: 1368-1379.
    • (2010) J Clin Invest , vol.120 , pp. 1368-1379
    • Wilson, E.H.1    Weninger, W.2    Hunter, C.A.3
  • 5
    • 0025289784 scopus 로고
    • Cellular immunoregulatory mechanisms in the central nervous system: Characterization of noninflammatory and inflammatory cerebrospinal fluid lymphocytes
    • DOI 10.1002/ana.410270611
    • Matsui M, Mori KJ, Saida T (1990) Cellular immunoregulatory mechanisms in the central nervous system: characterization of noninflammatory and inflammatory cerebrospinal fluid lymphocytes. Ann Neurol 27: 647-651. (Pubitemid 20177414)
    • (1990) Annals of Neurology , vol.27 , Issue.6 , pp. 647-651
    • Matsui, M.1    Mori, K.J.2    Saida, T.3
  • 6
    • 56149103896 scopus 로고    scopus 로고
    • Macrophage polarization in bacterial infections
    • Benoit M, Desnues B, Mege JL (2008) Macrophage polarization in bacterial infections. J Immunol 181: 3733-3739.
    • (2008) J Immunol , vol.181 , pp. 3733-3739
    • Benoit, M.1    Desnues, B.2    Mege, J.L.3
  • 7
    • 77956976681 scopus 로고    scopus 로고
    • Macrophage plasticity and interaction with lymphocyte subsets: Cancer as a paradigm
    • Biswas SK, Mantovani A (2010) Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm. Nat Immunol 11: 889-896.
    • (2010) Nat Immunol , vol.11 , pp. 889-896
    • Biswas, S.K.1    Mantovani, A.2
  • 8
    • 33750036957 scopus 로고    scopus 로고
    • Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD
    • Colton CA, Mott RT, Sharpe H, Xu Q, Van Nostrand WE, et al. (2006) Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD. J Neuroinflammation 3: 27.
    • (2006) J Neuroinflammation , vol.3 , pp. 27
    • Colton, C.A.1    Mott, R.T.2    Sharpe, H.3    Xu, Q.4    Van Nostrand, W.E.5
  • 9
    • 0036839143 scopus 로고    scopus 로고
    • Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
    • DOI 10.1016/S1471-4906(02)02302-5, PII S1471490602023025
    • Mantovani A, Sozzani S, Locati M, Allavena P, Sica A (2002) Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23: 549-555. (Pubitemid 35223554)
    • (2002) Trends in Immunology , vol.23 , Issue.11 , pp. 549-555
    • Mantovani, A.1    Sozzani, S.2    Locati, M.3    Allavena, P.4    Sica, A.5
  • 10
    • 78149435065 scopus 로고    scopus 로고
    • The myeloid cells of the central nervous system parenchyma
    • Ransohoff RM, Cardona AE (2010) The myeloid cells of the central nervous system parenchyma. Nature 468: 253-262.
    • (2010) Nature , vol.468 , pp. 253-262
    • Ransohoff, R.M.1    Cardona, A.E.2
  • 12
    • 51449097093 scopus 로고    scopus 로고
    • Neuroimmunology of central nervous system viral infections: The cells, molecules and mechanisms involved
    • Savarin C, Bergmann CC (2008) Neuroimmunology of central nervous system viral infections: the cells, molecules and mechanisms involved. Curr Opin Pharmacol 8: 472-479.
    • (2008) Curr Opin Pharmacol , vol.8 , pp. 472-479
    • Savarin, C.1    Bergmann, C.C.2
  • 13
    • 67649717023 scopus 로고    scopus 로고
    • The psychoneuroimmunology of depression
    • Leonard BE, Myint A (2009) The psychoneuroimmunology of depression. Hum Psychopharmacol 24: 165-175.
    • (2009) Hum Psychopharmacol , vol.24 , pp. 165-175
    • Leonard, B.E.1    Myint, A.2
  • 14
    • 77952513645 scopus 로고    scopus 로고
    • Inflammatory mechanisms in ischemic stroke: Role of inflammatory cells
    • Jin R, Yang G, Li G (2010) Inflammatory mechanisms in ischemic stroke: role of inflammatory cells. J Leukoc Biol 87: 779-789.
    • (2010) J Leukoc Biol , vol.87 , pp. 779-789
    • Jin, R.1    Yang, G.2    Li, G.3
  • 16
    • 77956302879 scopus 로고    scopus 로고
    • Inflammation in neurological disorders: A help or a hindrance?
    • Wee Yong V (2010) Inflammation in neurological disorders: a help or a hindrance? Neuroscientist 16: 408-420.
    • (2010) Neuroscientist , vol.16 , pp. 408-420
    • Wee Yong, V.1
  • 19
    • 27744464859 scopus 로고    scopus 로고
    • The microglial "activation" continuum: From innate to adaptive responses
    • Town T, Nikolic V, Tan J (2005) The microglial "activation" continuum: from innate to adaptive responses. J Neuroinflammation 2: 24.
    • (2005) J Neuroinflammation , vol.2 , pp. 24
    • Town, T.1    Nikolic, V.2    Tan, J.3
  • 20
    • 84864055056 scopus 로고    scopus 로고
    • Lipopolysaccha-ride-induced interleukin (IL)-4 receptor-alpha expression and corresponding sensitivity to the M2 promoting effects of IL-4 are impaired in microglia of aged mice
    • Fenn AM, Henry CJ, Huang Y, Dugan A, Godbout JP (2011) Lipopolysaccha-ride-induced interleukin (IL)-4 receptor-alpha expression and corresponding sensitivity to the M2 promoting effects of IL-4 are impaired in microglia of aged mice. Brain Behav Immun.
    • (2011) Brain Behav Immun
    • Fenn, A.M.1    Henry, C.J.2    Huang, Y.3    Dugan, A.4    Godbout, J.P.5
  • 21
    • 84865973639 scopus 로고    scopus 로고
    • The classification of microglial activation phenotypes on neurodegeneration and regeneration in Alzheimer's disease brain
    • Warsz
    • Varnum MM, Ikezu T (2012) The classification of microglial activation phenotypes on neurodegeneration and regeneration in Alzheimer's disease brain. Arch Immunol Ther Exp (Warsz) 60: 251-266.
    • (2012) Arch Immunol Ther Exp , vol.60 , pp. 251-266
    • Varnum, M.M.1    Ikezu, T.2
  • 23
    • 61849137222 scopus 로고    scopus 로고
    • Many roads to maturity: MicroRNA biogenesis pathways and their regulation
    • Winter J, Jung S, Keller S, Gregory RI, Diederichs S (2009) Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat Cell Biol 11: 228-234.
    • (2009) Nat Cell Biol , vol.11 , pp. 228-234
    • Winter, J.1    Jung, S.2    Keller, S.3    Gregory, R.I.4    Diederichs, S.5
  • 26
    • 79952186298 scopus 로고    scopus 로고
    • MicroRNAs: The fine-tuners of Toll-like receptor signalling
    • O'Neill LA, Sheedy FJ, McCoy CE (2011) MicroRNAs: the fine-tuners of Toll-like receptor signalling. Nat Rev Immunol 11: 163-175.
    • (2011) Nat Rev Immunol , vol.11 , pp. 163-175
    • O'Neill, L.A.1    Sheedy, F.J.2    McCoy, C.E.3
  • 27
    • 78651247933 scopus 로고    scopus 로고
    • MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway
    • Ponomarev ED, Veremeyko T, Barteneva N, Krichevsky AM, Weiner HL (2011) MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-alpha-PU.1 pathway. Nat Med 17: 64-70.
    • (2011) Nat Med , vol.17 , pp. 64-70
    • Ponomarev, E.D.1    Veremeyko, T.2    Barteneva, N.3    Krichevsky, A.M.4    Weiner, H.L.5
  • 28
    • 67650539049 scopus 로고    scopus 로고
    • CCL2 accelerates microglia-mediated Abeta oligomer formation and progression of neurocognitive dysfunction
    • Kiyota T, Yamamoto M, Xiong H, Lambert MP, Klein WL, et al. (2009) CCL2 accelerates microglia-mediated Abeta oligomer formation and progression of neurocognitive dysfunction. PLoS One 4: e6197.
    • (2009) PLoS One , vol.4
    • Kiyota, T.1    Yamamoto, M.2    Xiong, H.3    Lambert, M.P.4    Klein, W.L.5
  • 29
    • 34248673126 scopus 로고    scopus 로고
    • Isolation of murine microglial cells for RNA analysis or flow cytometry
    • DOI 10.1038/nprot.2006.327, PII NPROT.2006.327
    • Cardona AE, Huang D, Sasse ME, Ransohoff RM (2006) Isolation of murine microglial cells for RNA analysis or flow cytometry. Nat Protoc 1: 1947-1951. (Pubitemid 46773316)
    • (2006) Nature Protocols , vol.1 , Issue.4 , pp. 1947-1951
    • Cardona, A.E.1    Huang, D.2    Sasse, M.E.3    Ransohoff, R.M.4
  • 30
    • 52049087817 scopus 로고    scopus 로고
    • Magnetic cell sorting: A fast and effective method of concurrent isolation of high purity viable astrocytes and microglia from neonatal mouse brain tissue
    • Marek R, Caruso M, Rostami A, Grinspan JB, Das Sarma J (2008) Magnetic cell sorting: a fast and effective method of concurrent isolation of high purity viable astrocytes and microglia from neonatal mouse brain tissue. J Neurosci Methods 175: 108-118.
    • (2008) J Neurosci Methods , vol.175 , pp. 108-118
    • Marek, R.1    Caruso, M.2    Rostami, A.3    Grinspan, J.B.4    Das Sarma, J.5
  • 31
    • 37349042181 scopus 로고    scopus 로고
    • Computational methods for analysis of cellular functions and pathways collectively targeted by differentially expressed microRNA
    • Gusev Y (2008) Computational methods for analysis of cellular functions and pathways collectively targeted by differentially expressed microRNA. Methods 44: 61-72.
    • (2008) Methods , vol.44 , pp. 61-72
    • Gusev, Y.1
  • 32
    • 68949204302 scopus 로고    scopus 로고
    • Strategies and issues in the detection of pathway enrichment in genome-wide association studies
    • Hong MG, Pawitan Y, Magnusson PK, Prince JA (2009) Strategies and issues in the detection of pathway enrichment in genome-wide association studies. Hum Genet 126: 289-301.
    • (2009) Hum Genet , vol.126 , pp. 289-301
    • Hong, M.G.1    Pawitan, Y.2    Magnusson, P.K.3    Prince, J.A.4
  • 34
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • DOI 10.1016/j.cell.2004.12.035, PII S0092867404012607
    • Lewis BP, Burge CB, Bartel DP (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20. (Pubitemid 40094598)
    • (2005) Cell , vol.120 , Issue.1 , pp. 15-20
    • Lewis, B.P.1    Burge, C.B.2    Bartel, D.P.3
  • 36
    • 44449089166 scopus 로고    scopus 로고
    • GeneVenn - A web application for comparing gene lists using Venn diagrams
    • Pirooznia M, Nagarajan V, Deng Y (2007) GeneVenn - A web application for comparing gene lists using Venn diagrams. Bioinformation 1: 420-422.
    • (2007) Bioinformation , vol.1 , pp. 420-422
    • Pirooznia, M.1    Nagarajan, V.2    Deng, Y.3
  • 37
    • 34547644274 scopus 로고    scopus 로고
    • Transcriptome analysis of murine macrophages in response to infection with Streptococcus pyogenes reveals an unusual activation program
    • DOI 10.1128/IAI.00181-07
    • Goldmann O, von Kockritz-Blickwede M, Holtje C, Chhatwal GS, Geffers R, et al. (2007) Transcriptome analysis of murine macrophages in response to infection with Streptococcus pyogenes reveals an unusual activation program. Infect Immun 75: 4148-4157. (Pubitemid 47206314)
    • (2007) Infection and Immunity , vol.75 , Issue.8 , pp. 4148-4157
    • Goldmann, O.1    Von Kockritz-Blickwede, M.2    Holtje, C.3    Chhatwal, G.S.4    Geffers, R.5    Medina, E.6
  • 39
    • 33750813483 scopus 로고    scopus 로고
    • Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: New molecules and patterns of gene expression
    • Martinez FO, Gordon S, Locati M, Mantovani A (2006) Transcriptional profiling of the human monocyte-to-macrophage differentiation and polarization: new molecules and patterns of gene expression. J Immunol 177: 7303-7311. (Pubitemid 44715100)
    • (2006) Journal of Immunology , vol.177 , Issue.10 , pp. 7303-7311
    • Martinez, F.O.1    Gordon, S.2    Locati, M.3    Mantovani, A.4
  • 40
    • 77955417711 scopus 로고    scopus 로고
    • Comprehensive analysis of TLR4-induced transcriptional responses in interleukin 4-primed mouse macrophages
    • El Chartouni C, Rehli M (2010) Comprehensive analysis of TLR4-induced transcriptional responses in interleukin 4-primed mouse macrophages. Immunobiology 215: 780-787.
    • (2010) Immunobiology , vol.215 , pp. 780-787
    • El Chartouni, C.1    Rehli, M.2
  • 42
    • 67349251479 scopus 로고    scopus 로고
    • Characterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions: Effects of oligomeric and fibrillar amyloidbeta
    • Michelucci A, Heurtaux T, Grandbarbe L, Morga E, Heuschling P (2009) Characterization of the microglial phenotype under specific pro-inflammatory and anti-inflammatory conditions: Effects of oligomeric and fibrillar amyloidbeta. J Neuroimmunol 210: 3-12.
    • (2009) J Neuroimmunol , vol.210 , pp. 3-12
    • Michelucci, A.1    Heurtaux, T.2    Grandbarbe, L.3    Morga, E.4    Heuschling, P.5
  • 43
    • 0242421851 scopus 로고    scopus 로고
    • IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype
    • Loke P, Nair MG, Parkinson J, Guiliano D, Blaxter M, et al. (2002) IL-4 dependent alternatively-activated macrophages have a distinctive in vivo gene expression phenotype. BMC Immunol 3: 7.
    • (2002) BMC Immunol , vol.3 , pp. 7
    • Loke, P.1    Nair, M.G.2    Parkinson, J.3    Guiliano, D.4    Blaxter, M.5
  • 44
    • 7644231561 scopus 로고    scopus 로고
    • The chemokine system in diverse forms of macrophage activation and polarization
    • DOI 10.1016/j.it.2004.09.015, PII S1471490604002959
    • Mantovani A, Sica A, Sozzani S, Allavena P, Vecchi A, et al. (2004) The chemokine system in diverse forms of macrophage activation and polarization. Trends Immunol 25: 677-686. (Pubitemid 39457982)
    • (2004) Trends in Immunology , vol.25 , Issue.12 , pp. 677-686
    • Mantovani, A.1    Sica, A.2    Sozzani, S.3    Allavena, P.4    Vecchi, A.5    Locati, M.6
  • 45
    • 77951203709 scopus 로고    scopus 로고
    • Microarray analysis identifies altered regulation of nuclear receptor family members in the pre-disease state of multiple sclerosis
    • Achiron A, Grotto I, Balicer R, Magalashvili D, Feldman A, et al. (2010) Microarray analysis identifies altered regulation of nuclear receptor family members in the pre-disease state of multiple sclerosis. Neurobiol Dis 38: 201-209.
    • (2010) Neurobiol Dis , vol.38 , pp. 201-209
    • Achiron, A.1    Grotto, I.2    Balicer, R.3    Magalashvili, D.4    Feldman, A.5
  • 46
    • 84893170964 scopus 로고    scopus 로고
    • Regulation of microglia activation and deactivation by nuclear receptors
    • Saijo K, Crotti A, Glass CK (2012) Regulation of microglia activation and deactivation by nuclear receptors. Glia.
    • (2012) Glia
    • Saijo, K.1    Crotti, A.2    Glass, C.K.3
  • 47
    • 79960648178 scopus 로고    scopus 로고
    • Evidence for the complexity of microRNA-mediated regulation in ovarian cancer: A systems approach
    • Shahab SW, Matyunina LV, Mezencev R, Walker LD, Bowen NJ, et al. (2011) Evidence for the complexity of microRNA-mediated regulation in ovarian cancer: a systems approach. PLoS One 6: e22508.
    • (2011) PLoS One , vol.6
    • Shahab, S.W.1    Matyunina, L.V.2    Mezencev, R.3    Walker, L.D.4    Bowen, N.J.5
  • 48
    • 85027956278 scopus 로고    scopus 로고
    • Rheumatoid arthritis: MiR-155 mediates inflammation
    • Leah E (2011) Rheumatoid arthritis: miR-155 mediates inflammation. Nat Rev Rheumatol 7: 437.
    • (2011) Nat Rev Rheumatol , vol.7 , pp. 437
    • Leah, E.1
  • 49
    • 80052661268 scopus 로고    scopus 로고
    • Silencing microRNA-155 ameliorates experimental autoimmune encephalomyelitis
    • Murugaiyan G, Beynon V, Mittal A, Joller N, Weiner HL (2011) Silencing microRNA-155 ameliorates experimental autoimmune encephalomyelitis. J Immunol 187: 2213-2221.
    • (2011) J Immunol , vol.187 , pp. 2213-2221
    • Murugaiyan, G.1    Beynon, V.2    Mittal, A.3    Joller, N.4    Weiner, H.L.5
  • 50
    • 83055176904 scopus 로고    scopus 로고
    • miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production
    • Cardoso AL, Guedes JR, Pereira de Almeida L, Pedroso de Lima MC (2012) miR-155 modulates microglia-mediated immune response by down-regulating SOCS-1 and promoting cytokine and nitric oxide production. Immunology 135: 73-88.
    • (2012) Immunology , vol.135 , pp. 73-88
    • Cardoso, A.L.1    Guedes, J.R.2    Pereira De Almeida, L.3    Pedroso De Lima, M.C.4
  • 51
    • 84862792644 scopus 로고    scopus 로고
    • MicroRNA-449a acts as a tumor suppressor in human bladder cancer through the regulation of pocket proteins
    • Chen H, Lin YW, Mao YQ, Wu J, Liu YF, et al. (2012) MicroRNA-449a acts as a tumor suppressor in human bladder cancer through the regulation of pocket proteins. Cancer Lett 320: 40-47.
    • (2012) Cancer Lett , vol.320 , pp. 40-47
    • Chen, H.1    Lin, Y.W.2    Mao, Y.Q.3    Wu, J.4    Liu, Y.F.5
  • 53
    • 70350111289 scopus 로고    scopus 로고
    • miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A
    • Yang X, Feng M, Jiang X, Wu Z, Li Z, et al. (2009) miR-449a and miR-449b are direct transcriptional targets of E2F1 and negatively regulate pRb-E2F1 activity through a feedback loop by targeting CDK6 and CDC25A. Genes Dev 23: 2388-2393.
    • (2009) Genes Dev , vol.23 , pp. 2388-2393
    • Yang, X.1    Feng, M.2    Jiang, X.3    Wu, Z.4    Li, Z.5
  • 54
    • 79954545144 scopus 로고    scopus 로고
    • microRNA-145 suppresses lung adenocarcinoma-initiating cell proliferation by targeting OCT4
    • Yin R, Zhang S, Wu Y, Fan X, Jiang F, et al. (2011) microRNA-145 suppresses lung adenocarcinoma-initiating cell proliferation by targeting OCT4. Oncol Rep 25: 1747-1754.
    • (2011) Oncol Rep , vol.25 , pp. 1747-1754
    • Yin, R.1    Zhang, S.2    Wu, Y.3    Fan, X.4    Jiang, F.5
  • 55
    • 79959828991 scopus 로고    scopus 로고
    • Inhibition of house dust mite-induced allergic airways disease by antagonism of microRNA-145 is comparable to glucocorticoid treatment
    • Collison A, Mattes J, Plank M, Foster PS (2011) Inhibition of house dust mite-induced allergic airways disease by antagonism of microRNA-145 is comparable to glucocorticoid treatment. J Allergy Clin Immunol 128: 160-167 e164.
    • (2011) J Allergy Clin Immunol , vol.128
    • Collison, A.1    Mattes, J.2    Plank, M.3    Foster, P.S.4
  • 56
    • 77955508072 scopus 로고    scopus 로고
    • Costimulation-dependent expression of microRNA-214 increases the ability of T cells to proliferate by targeting Pten
    • Jindra PT, Bagley J, Godwin JG, Iacomini J (2010) Costimulation-dependent expression of microRNA-214 increases the ability of T cells to proliferate by targeting Pten. J Immunol 185: 990-997.
    • (2010) J Immunol , vol.185 , pp. 990-997
    • Jindra, P.T.1    Bagley, J.2    Godwin, J.G.3    Iacomini, J.4
  • 57
    • 54149095553 scopus 로고    scopus 로고
    • Biological principles of microRNA-mediated regulation: Shared themes amid diversity
    • Flynt AS, Lai EC (2008) Biological principles of microRNA-mediated regulation: shared themes amid diversity. Nat Rev Genet 9: 831-842.
    • (2008) Nat Rev Genet , vol.9 , pp. 831-842
    • Flynt, A.S.1    Lai, E.C.2
  • 58
    • 70349882120 scopus 로고    scopus 로고
    • Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses
    • Amit I, Garber M, Chevrier N, Leite AP, Donner Y, et al. (2009) Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses. Science 326: 257-263.
    • (2009) Science , vol.326 , pp. 257-263
    • Amit, I.1    Garber, M.2    Chevrier, N.3    Leite, A.P.4    Donner, Y.5
  • 59
    • 41849123062 scopus 로고    scopus 로고
    • Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamics
    • Ramsey SA, Klemm SL, Zak DE, Kennedy KA, Thorsson V, et al. (2008) Uncovering a macrophage transcriptional program by integrating evidence from motif scanning and expression dynamics. PLoS Comput Biol 4: e1000021.
    • (2008) PLoS Comput Biol , vol.4
    • Ramsey, S.A.1    Klemm, S.L.2    Zak, D.E.3    Kennedy, K.A.4    Thorsson, V.5
  • 61
    • 0034544564 scopus 로고    scopus 로고
    • IL-4-activated STAT-6 inhibits IFN-gamma-induced CD40 gene expression in macrophages/microglia
    • Nguyen VT, Benveniste EN (2000) IL-4-activated STAT-6 inhibits IFN-gamma-induced CD40 gene expression in macrophages/microglia. J Immunol 165: 6235-6243.
    • (2000) J Immunol , vol.165 , pp. 6235-6243
    • Nguyen, V.T.1    Benveniste, E.N.2
  • 62
    • 67449105513 scopus 로고    scopus 로고
    • IL-4 stimulates mouse macrophages to express APRIL through p38MAPK and two different downstream molecules, CREB and Stat6
    • Jang YS, Kim HA, Park SR, Lee MR, Park JB, et al. (2009) IL-4 stimulates mouse macrophages to express APRIL through p38MAPK and two different downstream molecules, CREB and Stat6. Cytokine 47: 43-47.
    • (2009) Cytokine , vol.47 , pp. 43-47
    • Jang, Y.S.1    Kim, H.A.2    Park, S.R.3    Lee, M.R.4    Park, J.B.5
  • 63
    • 0032974257 scopus 로고    scopus 로고
    • Interleukin-4-mediated inhibition of nitric oxide production in interferon-gamma-treated and virus-infected macrophages
    • DOI 10.1046/j.1365-3083.1999.00495.x
    • Paludan SR, Ellermann-Eriksen S, Lovmand J, Mogensen SC (1999) Interleukin-4-mediated inhibition of nitric oxide production in interferon-gamma-treated and virus-infected macrophages. Scand J Immunol 49: 169-176. (Pubitemid 29096313)
    • (1999) Scandinavian Journal of Immunology , vol.49 , Issue.2 , pp. 169-176
    • Paludan, S.R.1    Ellermann-Eriksen, S.2    Lovmand, J.3    Mogensen, S.C.4
  • 64
    • 84855686976 scopus 로고    scopus 로고
    • Resveratrol mitigates lipopolysaccharide- and Abeta-mediated microglial inflammation by inhibiting the TLR4/NF-kappaB/STAT signaling cascade
    • Capiralla H, Vingtdeux V, Zhao H, Sankowski R, Al-Abed Y, et al. (2012) Resveratrol mitigates lipopolysaccharide- and Abeta-mediated microglial inflammation by inhibiting the TLR4/NF-kappaB/STAT signaling cascade. J Neurochem 120: 461-472.
    • (2012) J Neurochem , vol.120 , pp. 461-472
    • Capiralla, H.1    Vingtdeux, V.2    Zhao, H.3    Sankowski, R.4    Al-Abed, Y.5
  • 65
    • 0345016388 scopus 로고    scopus 로고
    • Curcumin Suppresses Janus Kinase-STAT Inflammatory Signaling through Activation of Src Homology 2 Domain-Containing Tyrosine Phosphatase 2 in Brain Microglia
    • Kim HY, Park EJ, Joe EH, Jou I (2003) Curcumin suppresses Janus kinase-STAT inflammatory signaling through activation of Src homology 2 domain-containing tyrosine phosphatase 2 in brain microglia. J Immunol 171: 6072-6079. (Pubitemid 37467228)
    • (2003) Journal of Immunology , vol.171 , Issue.11 , pp. 6072-6079
    • Kim, H.Y.1    Park, E.J.2    Joe, E.-H.3    Jou, I.4
  • 66
    • 84859473951 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation
    • Qin H, Yeh WI, De Sarno P, Holdbrooks AT, Liu Y, et al. (2012) Signal transducer and activator of transcription-3/suppressor of cytokine signaling-3 (STAT3/SOCS3) axis in myeloid cells regulates neuroinflammation. Proc Natl Acad Sci U S A 109: 5004-5009.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 5004-5009
    • Qin, H.1    Yeh, W.I.2    De Sarno, P.3    Holdbrooks, A.T.4    Liu, Y.5
  • 68
    • 0034717067 scopus 로고    scopus 로고
    • The acute phase response is associated with retinoid X receptor repression in rodent liver
    • DOI 10.1074/jbc.M000953200
    • Beigneux AP, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR (2000) The acute phase response is associated with retinoid X receptor repression in rodent liver. J Biol Chem 275: 16390-16399. (Pubitemid 30366957)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.21 , pp. 16390-16399
    • Beigneux, A.P.1    Moser, A.H.2    Shigenaga, J.K.3    Grunfeld, C.4    Feingold, K.R.5
  • 70
    • 41749084171 scopus 로고    scopus 로고
    • Agonists of PPAR-alpha, PPAR-gamma, and RXR inhibit the formation of foam cells from macrophages in mice with inflammation
    • DOI 10.1007/s10517-007-0413-3
    • Dushkin MI, Khoshchenko OM, Posokhova EN, Schvarts Y (2007) Agonists of PPAR-alpha, PPAR-gamma, and RXR inhibit the formation of foam cells from macrophages in mice with inflammation. Bull Exp Biol Med 144: 713-716. (Pubitemid 351486653)
    • (2007) Bulletin of Experimental Biology and Medicine , vol.144 , Issue.5 , pp. 713-716
    • Dushkin, M.I.1    Khoshchenko, O.M.2    Posokhova, E.N.3    Schvarts, Y.Sh.4
  • 72
    • 27444439757 scopus 로고    scopus 로고
    • Downregulation of liver X receptor-alpha in mouse kidney and HK-2 proximal tubular cells by LPS and cytokines
    • DOI 10.1194/jlr.M500134-JLR200
    • Wang Y, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR (2005) Downregulation of liver X receptor-alpha in mouse kidney and HK-2 proximal tubular cells by LPS and cytokines. J Lipid Res 46: 2377-2387. (Pubitemid 41532526)
    • (2005) Journal of Lipid Research , vol.46 , Issue.11 , pp. 2377-2387
    • Wang, Y.1    Moser, A.H.2    Shigenaga, J.K.3    Grunfeld, C.4    Feingold, K.R.5
  • 73
    • 84855281838 scopus 로고    scopus 로고
    • Neuroprotective Mechanisms of PPARdelta: Modulation of Oxidative Stress and Inflammatory Processes
    • Schnegg CI, Robbins ME (2011) Neuroprotective Mechanisms of PPARdelta: Modulation of Oxidative Stress and Inflammatory Processes. PPAR Res 2011: 373560.
    • (2011) PPAR Res , vol.2011 , pp. 373560
    • Schnegg, C.I.1    Robbins, M.E.2
  • 74
    • 56249140398 scopus 로고    scopus 로고
    • Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors
    • DOI 10.1016/j.gde.2008.07.016, PII S0959437X08000968
    • Hong C, Tontonoz P (2008) Coordination of inflammation and metabolism by PPAR and LXR nuclear receptors. Curr Opin Genet Dev 18: 461-467. (Pubitemid 50280209)
    • (2008) Current Opinion in Genetics and Development , vol.18 , Issue.5 , pp. 461-467
    • Hong, C.1    Tontonoz, P.2
  • 75
    • 1242317642 scopus 로고    scopus 로고
    • Ligands for the peroxisome proliferator-activated receptor-gamma and the retinoid X receptor exert additive anti-inflammatory effects on experimental autoimmune encephalomyelitis
    • DOI 10.1016/j.jneuroim.2003.11.010
    • Diab A, Hussain RZ, Lovett-Racke AE, Chavis JA, Drew PD, et al. (2004) Ligands for the peroxisome proliferator-activated receptor-gamma and the retinoid X receptor exert additive anti-inflammatory effects on experimental autoimmune encephalomyelitis. J Neuroimmunol 148: 116-126. (Pubitemid 38229564)
    • (2004) Journal of Neuroimmunology , vol.148 , Issue.1-2 , pp. 116-126
    • Diab, A.1    Hussain, R.Z.2    Lovett-Racke, A.E.3    Chavis, J.A.4    Drew, P.D.5    Racke, M.K.6
  • 77
    • 78651311722 scopus 로고    scopus 로고
    • PPARgamma agonist pioglitazone inhibits microglia inflammation by blocking p38 mitogen-activated protein kinase signaling pathways
    • Ji H, Wang H, Zhang F, Li X, Xiang L, et al. (2010) PPARgamma agonist pioglitazone inhibits microglia inflammation by blocking p38 mitogen-activated protein kinase signaling pathways. Inflamm Res 59: 921-929.
    • (2010) Inflamm Res , vol.59 , pp. 921-929
    • Ji, H.1    Wang, H.2    Zhang, F.3    Li, X.4    Xiang, L.5
  • 78
    • 25444528680 scopus 로고    scopus 로고
    • Agonists for the peroxisome proliferator-activated receptor-alpha and the retinoid X receptor inhibit inflammatory responses of microglia
    • DOI 10.1002/jnr.20518
    • Xu J, Storer PD, Chavis JA, Racke MK, Drew PD (2005) Agonists for the peroxisome proliferator-activated receptor-alpha and the retinoid X receptor inhibit inflammatory responses of microglia. J Neurosci Res 81: 403-411. (Pubitemid 41359295)
    • (2005) Journal of Neuroscience Research , vol.81 , Issue.3 , pp. 403-411
    • Xu, J.1    Storer, P.D.2    Chavis, J.A.3    Racke, M.K.4    Drew, P.D.5
  • 79
    • 33846821853 scopus 로고    scopus 로고
    • Liver X receptor and retinoid X receptor agonists inhibit inflammatory responses of microglia and astrocytes
    • DOI 10.1016/j.jneuroim.2006.11.007, PII S0165572806004449
    • Zhang-Gandhi CX, Drew PD (2007) Liver X receptor and retinoid X receptor agonists inhibit inflammatory responses of microglia and astrocytes. J Neuroimmunol 183: 50-59. (Pubitemid 46204908)
    • (2007) Journal of Neuroimmunology , vol.183 , Issue.1-2 , pp. 50-59
    • Zhang-Gandhi, C.X.1    Drew, P.D.2
  • 80
    • 84864249514 scopus 로고    scopus 로고
    • Mechanisms underlying the rapid peroxisome proliferator-activated receptor-gamma-mediated amyloid clearance and reversal of cognitive deficits in a murine model of Alzheimer's disease
    • Mandrekar-Colucci S, Karlo JC, Landreth GE (2012) Mechanisms underlying the rapid peroxisome proliferator-activated receptor-gamma-mediated amyloid clearance and reversal of cognitive deficits in a murine model of Alzheimer's disease. J Neurosci 32: 10117-10128.
    • (2012) J Neurosci , vol.32 , pp. 10117-10128
    • Mandrekar-Colucci, S.1    Karlo, J.C.2    Landreth, G.E.3
  • 81
    • 84875255948 scopus 로고    scopus 로고
    • Expression profiles of miRNAs in polarized macrophages
    • Zhang Y, Zhang M, Zhong M, Suo Q, Lv K (2013) Expression profiles of miRNAs in polarized macrophages. Int J Mol Med 31: 797-802.
    • (2013) Int J Mol Med , vol.31 , pp. 797-802
    • Zhang, Y.1    Zhang, M.2    Zhong, M.3    Suo, Q.4    Lv, K.5
  • 83
    • 33646236121 scopus 로고    scopus 로고
    • Kruppel-like factor 2 (KLF2) regulates proinflammatory activation of monocytes
    • Das H, Kumar A, Lin Z, Patino WD, Hwang PM, et al. (2006) Kruppel-like factor 2 (KLF2) regulates proinflammatory activation of monocytes. Proc Natl Acad Sci U S A 103: 6653-6658.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 6653-6658
    • Das, H.1    Kumar, A.2    Lin, Z.3    Patino, W.D.4    Hwang, P.M.5
  • 84
    • 79151484549 scopus 로고    scopus 로고
    • Oxidized LDL enhances pro-inflammatory responses of alternatively activated M2 macrophages: A crucial role for Kruppel-like factor 2
    • van Tits LJ, Stienstra R, van Lent PL, Netea MG, Joosten LA, et al. (2011) Oxidized LDL enhances pro-inflammatory responses of alternatively activated M2 macrophages: a crucial role for Kruppel-like factor 2. Atherosclerosis 214: 345-349.
    • (2011) Atherosclerosis , vol.214 , pp. 345-349
    • Van Tits, L.J.1    Stienstra, R.2    Van Lent, P.L.3    Netea, M.G.4    Joosten, L.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.