The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism

Cell Reports

Volumn 18, Issue 5, 2017, Pages 1241-1255

  Matalonga, Jonathan ^a   Glaria, Estibaliz ^a   Bresque, Mariana ^b   Escande, Carlos ^b   Carbó, José María ^a   Kiefer, Kerstin ^c   Vicente, Ruben ^c   León, Theresa E ^a   Beceiro, Susana ^d   Pascual García, Mónica ^a   Serret, Joan ^a   Sanjurjo, Lucía ^e   Morón Ros, Samantha ^a   Riera, Antoni ^a,f   Paytubi, Sonia ^a   Juarez, Antonio ^a,g   Sotillo, Fernando ^f   Lindbom, Lennart ^h   Caelles, Carme ^a   Sarrias, Maria Rosa ^e   Sancho, Jaime ⁱ   Castrillo, Antonio ^d   Chini, Eduardo N ^j   Valledor, Annabel F ^a   more..

^a UNIVERSITY OF BARCELONA   (Spain)

^b INSTITUT PASTEUR DE MONTEVIDEO   (Uruguay)

^c UNIVERSITAT POMPEU FABRA   (Spain)

^d INSTITUTO DE INVESTIGACIONES BIOMÉDICAS ALBERTO SOLS   (Spain)

^e Germans Trias i Pujol Research Institute in Health Sciences   (Spain)

^f INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^g INSTITUTE FOR BIOENGINEERING OF CATALONIA IBEC   (Spain)

^h KAROLINSKA INSTITUTE   (Sweden)

ⁱ INSTITUTO DE PARASITOLOGÍA Y BIOMEDICINA LÓPEZ NEYRA   (Spain)

^j Mayo Clinic College of Medicine   (United States)

more..

Author keywords

bacterial infection; CD38; cytoskeleton; LXR; macrophage; NAD; nuclear receptor

Indexed keywords

3 [3 [[2 CHLORO 3 (TRIFLUOROMETHYL)BENZYL](2 DIPHENYLETHYL)AMINO]PROPOXY]PHENYLACETIC ACID; CD38 ANTIGEN; F ACTIN; LIVER X RECEPTOR; N (2,2,2 TRIFLUOROETHYL) N [4 (2,2,2 TRIFLUORO 1 HYDROXY 1 TRIFLUOROMETHYLETHYL)PHENYL]BENZENESULFONAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; ADP RIBOSYL CYCLASE/CYCLIC ADP RIBOSE HYDROLASE 1; CELL RECEPTOR;

ACTIN FILAMENT; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CELL STRUCTURE; CONTROLLED STUDY; DRUG EFFECT; ENTEROINVASIVE ESCHERICHIA COLI; FEMALE; HOST PATHOGEN INTERACTION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE METABOLISM; OPSONIZATION; PROTEIN EXPRESSION; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; SALMONELLOSIS; TRANSCRIPTION INITIATION; ANIMAL; CELL LINE; CHLOROCEBUS AETHIOPS; CV-1 CELL LINE; MACROPHAGE; METABOLISM; PATHOGENICITY; RAW 264.7 CELL LINE;

ACTIN CYTOSKELETON; ADP-RIBOSYL CYCLASE 1; ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; FEMALE; LIVER X RECEPTORS; MACROPHAGES; MALE; MICE; NAD; RAW 264.7 CELLS; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SALMONELLA INFECTIONS; SALMONELLA TYPHIMURIUM;

EID: 85011691120     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2017.01.007     Document Type: Article

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