메뉴 건너뛰기




Volumn 17, Issue 1, 2014, Pages 131-143

Identification of a unique TGF-β-dependent molecular and functional signature in microglia

Author keywords

[No Author keywords available]

Indexed keywords


EID: 84893745524     PISSN: 10976256     EISSN: 15461726     Source Type: Journal    
DOI: 10.1038/nn.3599     Document Type: Article
Times cited : (1865)

References (60)
  • 1
    • 80053233055 scopus 로고    scopus 로고
    • Heterogeneity of CNS myeloid cells and their roles in neurodegeneration
    • Prinz, M., Priller, J., Sisodia, S.S. & Ransohoff, R.M. Heterogeneity of CNS myeloid cells and their roles in neurodegeneration. Nat. Neurosci. 14, 1227-1235 (2011).
    • (2011) Nat. Neurosci. , vol.14 , pp. 1227-1235
    • Prinz, M.1    Priller, J.2    Sisodia, S.S.3    Ransohoff, R.M.4
  • 2
    • 78149435065 scopus 로고    scopus 로고
    • The myeloid cells of the central nervous system parenchyma
    • Ransohoff, R.M. & Cardona, A.E. The myeloid cells of the central nervous system parenchyma. Nature 468, 253-262 (2010).
    • (2010) Nature , vol.468 , pp. 253-262
    • Ransohoff, R.M.1    Cardona, A.E.2
  • 3
    • 80355143546 scopus 로고    scopus 로고
    • Microglial cell origin and phenotypes in health and disease
    • Saijo, K. & Glass, C.K. Microglial cell origin and phenotypes in health and disease. Nat. Rev. Immunol. 11, 775-787 (2011).
    • (2011) Nat. Rev. Immunol. , vol.11 , pp. 775-787
    • Saijo, K.1    Glass, C.K.2
  • 4
    • 78149360132 scopus 로고    scopus 로고
    • Fate mapping analysis reveals that adult microglia derive from primitive macrophages
    • Ginhoux, F. et al. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science 330, 841-845 (2010).
    • (2010) Science , vol.330 , pp. 841-845
    • Ginhoux, F.1
  • 5
    • 84859508307 scopus 로고    scopus 로고
    • A lineage of myeloid cells independent of Myb and hematopoietic stem cells
    • Schulz, C. et al. A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science 336, 86-90 (2012).
    • (2012) Science , vol.336 , pp. 86-90
    • Schulz, C.1
  • 6
    • 84875892857 scopus 로고    scopus 로고
    • Microglia emerge from erythromyeloid precursors via Pu.1-and Irf8-dependent pathways
    • Kierdorf, K. et al. Microglia emerge from erythromyeloid precursors via Pu.1-and Irf8-dependent pathways. Nat. Neurosci. 16, 273-280 (2013).
    • (2013) Nat. Neurosci. , vol.16 , pp. 273-280
    • Kierdorf, K.1
  • 7
    • 84870907320 scopus 로고    scopus 로고
    • Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia
    • Greter, M. et al. Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia. Immunity 37, 1050-1060 (2012).
    • (2012) Immunity , vol.37 , pp. 1050-1060
    • Greter, M.1
  • 8
    • 80052246111 scopus 로고    scopus 로고
    • Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool
    • Ajami, B., Bennett, J.L., Krieger, C., McNagny, K.M. & Rossi, F.M. Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool. Nat. Neurosci. 14, 1142-1149 (2011).
    • (2011) Nat. Neurosci. , vol.14 , pp. 1142-1149
    • Ajami, B.1    Bennett, J.L.2    Krieger, C.3    McNagny, K.M.4    Rossi, F.M.5
  • 9
    • 78149438403 scopus 로고    scopus 로고
    • Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice
    • Saederup, N. et al. Selective chemokine receptor usage by central nervous system myeloid cells in CCR2-red fluorescent protein knock-in mice. PLoS ONE 5, e13693 (2010).
    • (2010) PLoS ONE , vol.5
    • Saederup, N.1
  • 10
    • 65149093082 scopus 로고    scopus 로고
    • Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease
    • King, I.L., Dickendesher, T.L. & Segal, B.M. Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease. Blood 113, 3190-3197 (2009).
    • (2009) Blood , vol.113 , pp. 3190-3197
    • King, I.L.1    Dickendesher, T.L.2    Segal, B.M.3
  • 11
    • 34247874753 scopus 로고    scopus 로고
    • Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice
    • Dimitrijevic, O.B., Stamatovic, S.M., Keep, R.F. & Andjelkovic, A.V. Absence of the chemokine receptor CCR2 protects against cerebral ischemia/reperfusion injury in mice. Stroke 38, 1345-1353 (2007).
    • (2007) Stroke , vol.38 , pp. 1345-1353
    • Dimitrijevic, O.B.1    Stamatovic, S.M.2    Keep, R.F.3    Andjelkovic, A.V.4
  • 12
    • 84865987121 scopus 로고    scopus 로고
    • Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS
    • Butovsky, O. et al. Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS. J. Clin. Invest. 122, 3063-3087 (2012).
    • (2012) J. Clin. Invest. , vol.122 , pp. 3063-3087
    • Butovsky, O.1
  • 13
    • 0037963473 scopus 로고    scopus 로고
    • Blood monocytes consist of two principal subsets with distinct migratory properties
    • [pii]
    • Geissmann, F., Jung, S. & Littman, D.R. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 19, 71-82 [pii] (2003).
    • (2003) Immunity , vol.19 , pp. 71-82
    • Geissmann, F.1    Jung, S.2    Littman, D.R.3
  • 14
    • 84867740805 scopus 로고    scopus 로고
    • Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages
    • Gautier, E.L. et al. Gene-expression profiles and transcriptional regulatory pathways that underlie the identity and diversity of mouse tissue macrophages. Nat. Immunol. 13, 1118-1128 (2012).
    • (2012) Nat. Immunol. , vol.13 , pp. 1118-1128
    • Gautier, E.L.1
  • 15
    • 36849033963 scopus 로고    scopus 로고
    • TAM receptors are pleiotropic inhibitors of the innate immune response
    • Rothlin, C.V., Ghosh, S., Zuniga, E.I., Oldstone, M.B. & Lemke, G. TAM receptors are pleiotropic inhibitors of the innate immune response. Cell 131, 1124-1136 (2007).
    • (2007) Cell , vol.131 , pp. 1124-1136
    • Rothlin, C.V.1    Ghosh, S.2    Zuniga, E.I.3    Oldstone, M.B.4    Lemke, G.5
  • 16
    • 84876775203 scopus 로고    scopus 로고
    • Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes
    • Hashimoto, D. et al. Tissue-resident macrophages self-maintain locally throughout adult life with minimal contribution from circulating monocytes. Immunity 38, 792-804 (2013).
    • (2013) Immunity , vol.38 , pp. 792-804
    • Hashimoto, D.1
  • 17
    • 84872765982 scopus 로고    scopus 로고
    • Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis
    • Yona, S. et al. Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity 38, 79-91 (2013).
    • (2013) Immunity , vol.38 , pp. 79-91
    • Yona, S.1
  • 18
    • 38149129457 scopus 로고    scopus 로고
    • A transcriptome database for astrocytes, neurons, and oligodendrocytes: A new resource for understanding brain development and function
    • Cahoy, J.D. et al. A transcriptome database for astrocytes, neurons, and oligodendrocytes: a new resource for understanding brain development and function. J. Neurosci. 28, 264-278 (2008).
    • (2008) J. Neurosci. , vol.28 , pp. 264-278
    • Cahoy, J.D.1
  • 19
    • 0030611964 scopus 로고    scopus 로고
    • PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors
    • Scott, E.W. et al. PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors. Immunity 6, 437-447 (1997).
    • (1997) Immunity , vol.6 , pp. 437-447
    • Scott, E.W.1
  • 20
    • 33750478657 scopus 로고    scopus 로고
    • Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis
    • Beers, D.R. et al. Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis. Proc. Natl. Acad. Sci. USA 103, 16021-16026 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 16021-16026
    • Beers, D.R.1
  • 21
    • 33845259342 scopus 로고    scopus 로고
    • The P2Y12 receptor regulates microglial activation by extracellular nucleotides
    • Haynes, S.E. et al. The P2Y12 receptor regulates microglial activation by extracellular nucleotides. Nat. Neurosci. 9, 1512-1519 (2006).
    • (2006) Nat. Neurosci. , vol.9 , pp. 1512-1519
    • Haynes, S.E.1
  • 22
    • 34248673126 scopus 로고    scopus 로고
    • Isolation of murine microglial cells for RNA analysis or flow cytometry
    • Cardona, A.E., Huang, D., Sasse, M.E. & Ransohoff, R.M. Isolation of murine microglial cells for RNA analysis or flow cytometry. Nat. Protoc. 1, 1947-1951 (2006).
    • (2006) Nat. Protoc. , vol.1 , pp. 1947-1951
    • Cardona, A.E.1    Huang, D.2    Sasse, M.E.3    Ransohoff, R.M.4
  • 23
    • 0034028817 scopus 로고    scopus 로고
    • Analysis of fractalkine receptor CX (3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion
    • Jung, S. et al. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol. Cell Biol. 20, 4106-4114 (2000).
    • (2000) Mol. Cell Biol. , vol.20 , pp. 4106-4114
    • Jung, S.1
  • 24
    • 77955908261 scopus 로고    scopus 로고
    • Generation of microglial cells from mouse embryonic stem cells
    • Beutner, C., Roy, K., Linnartz, B., Napoli, I. & Neumann, H. Generation of microglial cells from mouse embryonic stem cells. Nat. Protoc. 5, 1481-1494 (2010).
    • (2010) Nat. Protoc. , vol.5 , pp. 1481-1494
    • Beutner, C.1    Roy, K.2    Linnartz, B.3    Napoli, I.4    Neumann, H.5
  • 25
    • 84860666662 scopus 로고    scopus 로고
    • TGF-beta signaling through SMAD2/3 induces the quiescent microglial phenotype within the CNS environment
    • Abutbul, S. et al. TGF-beta signaling through SMAD2/3 induces the quiescent microglial phenotype within the CNS environment. Glia 60, 1160-1171 (2012).
    • (2012) Glia , vol.60 , pp. 1160-1171
    • Abutbul, S.1
  • 26
    • 0035725230 scopus 로고    scopus 로고
    • Astrocyte-released cytokines induce ramification and outward K+ channel expression in microglia via distinct signaling pathways
    • Schilling, T., Nitsch, R., Heinemann, U., Haas, D. & Eder, C. Astrocyte-released cytokines induce ramification and outward K+ channel expression in microglia via distinct signaling pathways. Eur. J. Neurosci. 14, 463-473 (2001).
    • (2001) Eur. J. Neurosci. , vol.14 , pp. 463-473
    • Schilling, T.1    Nitsch, R.2    Heinemann, U.3    Haas, D.4    Eder, C.5
  • 27
    • 84858072878 scopus 로고    scopus 로고
    • Comparison of polarization properties of human adult microglia and blood-derived macrophages
    • Durafourt, B.A. et al. Comparison of polarization properties of human adult microglia and blood-derived macrophages. Glia 60, 717-727 (2012).
    • (2012) Glia , vol.60 , pp. 717-727
    • Durafourt, B.A.1
  • 28
    • 33645527193 scopus 로고    scopus 로고
    • Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis
    • Butovsky, O. et al. Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis. J. Clin. Invest. 116, 905-915 (2006).
    • (2006) J. Clin. Invest. , vol.116 , pp. 905-915
    • Butovsky, O.1
  • 29
    • 0027531528 scopus 로고
    • Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death
    • Kulkarni, A.B. et al. Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death. Proc. Natl. Acad. Sci. USA 90, 770-774 (1993).
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 770-774
    • Kulkarni, A.B.1
  • 30
    • 0026799402 scopus 로고
    • Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
    • Shull, M.M. et al. Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature 359, 693-699 (1992).
    • (1992) Nature , vol.359 , pp. 693-699
    • Shull, M.M.1
  • 31
    • 0036372440 scopus 로고    scopus 로고
    • Transforming growth factor-beta in T-cell biology
    • Gorelik, L. & Flavell, R.A. Transforming growth factor-beta in T-cell biology. Nat. Rev. Immunol. 2, 46-53 (2002).
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 46-53
    • Gorelik, L.1    Flavell, R.A.2
  • 32
    • 33845942398 scopus 로고    scopus 로고
    • Th3 cells in peripheral tolerance. II. TGF-beta-transgenic Th3 cells rescue IL-2-deficient mice from autoimmunity
    • Carrier, Y., Yuan, J., Kuchroo, V.K. & Weiner, H.L. Th3 cells in peripheral tolerance. II. TGF-beta-transgenic Th3 cells rescue IL-2-deficient mice from autoimmunity. J. Immunol. 178, 172-178 (2007).
    • (2007) J. Immunol. , vol.178 , pp. 172-178
    • Carrier, Y.1    Yuan, J.2    Kuchroo, V.K.3    Weiner, H.L.4
  • 33
    • 84876494975 scopus 로고    scopus 로고
    • Impaired glutamate recycling and GluN2B-mediated neuronal calcium overload in mice lacking TGF-beta1 in the CNS
    • Koeglsperger, T. et al. Impaired glutamate recycling and GluN2B-mediated neuronal calcium overload in mice lacking TGF-beta1 in the CNS. Glia 61, 985-1002 (2013).
    • (2013) Glia , vol.61 , pp. 985-1002
    • Koeglsperger, T.1
  • 34
    • 0022387412 scopus 로고
    • Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain
    • Perry, V.H., Hume, D.A. & Gordon, S. Immunohistochemical localization of macrophages and microglia in the adult and developing mouse brain. Neuroscience 15, 313-326 (1985).
    • (1985) Neuroscience , vol.15 , pp. 313-326
    • Perry, V.H.1    Hume, D.A.2    Gordon, S.3
  • 35
    • 0030456368 scopus 로고    scopus 로고
    • A role for endogenous transforming growth factor beta 1 in Langerhans cell biology: The skin of transforming growth factor beta 1 null mice is devoid of epidermal Langerhans cell
    • Borkowski, T.A., Letterio, J.J., Farr, A.G. & Udey, M.C. A role for endogenous transforming growth factor beta 1 in Langerhans cell biology: the skin of transforming growth factor beta 1 null mice is devoid of epidermal Langerhans cells. J. Exp. Med. 184, 2417-2422 (1996).
    • (1996) J. Exp. Med. , vol.184 , pp. 2417-2422
    • Borkowski, T.A.1    Letterio, J.J.2    Farr, A.G.3    Udey, M.C.4
  • 36
    • 35748948090 scopus 로고    scopus 로고
    • Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cells
    • Kaplan, D.H. et al. Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cells. J. Exp. Med. 204, 2545-2552 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 2545-2552
    • Kaplan, D.H.1
  • 37
    • 0032737272 scopus 로고    scopus 로고
    • Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain
    • Alliot, F., Godin, I. & Pessac, B. Microglia derive from progenitors, originating from the yolk sac, and which proliferate in the brain. Brain Res. Dev. Brain Res. 117, 145-152 (1999).
    • (1999) Brain Res. Dev. Brain Res. , vol.117 , pp. 145-152
    • Alliot, F.1    Godin, I.2    Pessac, B.3
  • 38
    • 0035887068 scopus 로고    scopus 로고
    • Zebrafish early macrophages colonize cephalic mesenchyme and developing brain, retina, and epidermis through a M-CSF receptor-dependent invasive process
    • Herbomel, P., Thisse, B. & Thisse, C. Zebrafish early macrophages colonize cephalic mesenchyme and developing brain, retina, and epidermis through a M-CSF receptor-dependent invasive process. Dev. Biol. 238, 274-288 (2001).
    • (2001) Dev. Biol. , vol.238 , pp. 274-288
    • Herbomel, P.1    Thisse, B.2    Thisse, C.3
  • 39
    • 33846571886 scopus 로고    scopus 로고
    • The origin and cell lineage of microglia: New concepts
    • Chan, W.Y., Kohsaka, S. & Rezaie, P. The origin and cell lineage of microglia: new concepts. Brain Res. Rev. 53, 344-354 (2007).
    • (2007) Brain Res. Rev. , vol.53 , pp. 344-354
    • Chan, W.Y.1    Kohsaka, S.2    Rezaie, P.3
  • 41
    • 80052633284 scopus 로고    scopus 로고
    • Synaptic pruning by microglia is necessary for normal brain development
    • Paolicelli, R.C. et al. Synaptic pruning by microglia is necessary for normal brain development. Science 333, 1456-1458 (2011).
    • (2011) Science , vol.333 , pp. 1456-1458
    • Paolicelli, R.C.1
  • 42
    • 0025800595 scopus 로고
    • Localization and actions of transforming growth factor-beta s in the embryonic nervous system
    • Flanders, K.C. et al. Localization and actions of transforming growth factor-beta s in the embryonic nervous system. Development 113, 183-191 (1991).
    • (1991) Development , vol.113 , pp. 183-191
    • Flanders, K.C.1
  • 43
    • 77956530090 scopus 로고    scopus 로고
    • Smad3-dependent signaling underlies the TGF-beta1-mediated enhancement in astrocytic iNOS expression
    • Hamby, M.E., Hewett, J.A. & Hewett, S.J. Smad3-dependent signaling underlies the TGF-beta1-mediated enhancement in astrocytic iNOS expression. Glia 58, 1282-1291 (2010).
    • (2010) Glia , vol.58 , pp. 1282-1291
    • Hamby, M.E.1    Hewett, J.A.2    Hewett, S.J.3
  • 44
    • 0029819763 scopus 로고    scopus 로고
    • TGF-beta 1 protects hippocampal neurons against degeneration caused by transient global ischemia. Dose-response relationship and potential neuroprotective mechanisms
    • discussion 1615
    • Henrich-Noack, P., Prehn, J.H. & Krieglstein, J. TGF-beta 1 protects hippocampal neurons against degeneration caused by transient global ischemia. Dose-response relationship and potential neuroprotective mechanisms. Stroke 27, 1609-1614, discussion 1615 (1996).
    • (1996) Stroke , vol.27 , pp. 1609-1614
    • Henrich-Noack, P.1    Prehn, J.H.2    Krieglstein, J.3
  • 45
    • 0027508314 scopus 로고
    • Expression of transforming growth factor-beta 1 and interleukin-1 beta mRNA in rat brain following transient forebrain ischemia
    • Wiessner, C. et al. Expression of transforming growth factor-beta 1 and interleukin-1 beta mRNA in rat brain following transient forebrain ischemia. Acta Neuropathol. 86, 439-446 (1993).
    • (1993) Acta Neuropathol. , vol.86 , pp. 439-446
    • Wiessner, C.1
  • 46
    • 0031975391 scopus 로고    scopus 로고
    • Transforming growth factor-betas in neurodegenerative disease
    • Flanders, K.C., Ren, R.F. & Lippa, C.F. Transforming growth factor-betas in neurodegenerative disease. Prog. Neurobiol. 54, 71-85 (1998).
    • (1998) Prog. Neurobiol. , vol.54 , pp. 71-85
    • Flanders, K.C.1    Ren, R.F.2    Lippa, C.F.3
  • 47
    • 0347362913 scopus 로고    scopus 로고
    • Loss of TGF-beta 1 leads to increased neuronal cell death and microgliosis in mouse brain
    • Brionne, T.C., Tesseur, I., Masliah, E. & Wyss-Coray, T. Loss of TGF-beta 1 leads to increased neuronal cell death and microgliosis in mouse brain. Neuron 40, 1133-1145 (2003).
    • (2003) Neuron , vol.40 , pp. 1133-1145
    • Brionne, T.C.1    Tesseur, I.2    Masliah, E.3    Wyss-Coray, T.4
  • 48
    • 65249157852 scopus 로고    scopus 로고
    • Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals
    • Wake, H., Moorhouse, A.J., Jinno, S., Kohsaka, S. & Nabekura, J. Resting microglia directly monitor the functional state of synapses in vivo and determine the fate of ischemic terminals. J. Neurosci. 29, 3974-3980 (2009).
    • (2009) J. Neurosci. , vol.29 , pp. 3974-3980
    • Wake, H.1    Moorhouse, A.J.2    Jinno, S.3    Kohsaka, S.4    Nabekura, J.5
  • 49
    • 63049083734 scopus 로고    scopus 로고
    • A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death
    • Saijo, K. et al. A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death. Cell 137, 47-59 (2009).
    • (2009) Cell , vol.137 , pp. 47-59
    • Saijo, K.1
  • 50
    • 43949088191 scopus 로고    scopus 로고
    • Live imaging of neuronal degradation by microglia reveals a role for v0-ATPase a1 in phagosomal fusion in vivo
    • Peri, F. & Nusslein-Volhard, C. Live imaging of neuronal degradation by microglia reveals a role for v0-ATPase a1 in phagosomal fusion in vivo. Cell 133, 916-927 (2008).
    • (2008) Cell , vol.133 , pp. 916-927
    • Peri, F.1    Nusslein-Volhard, C.2
  • 51
    • 73949101833 scopus 로고    scopus 로고
    • The origin and development of nonlymphoid tissue CD103+ DCs
    • Ginhoux, F. et al. The origin and development of nonlymphoid tissue CD103+ DCs. J. Exp. Med. 206, 3115-3130 (2009).
    • (2009) J. Exp. Med. , vol.206 , pp. 3115-3130
    • Ginhoux, F.1
  • 52
    • 54449099068 scopus 로고    scopus 로고
    • Isolation and visualization of mouse placental hematopoietic stem cells
    • Gekas, C., Rhodes, K.E. & Mikkola, H.K. Isolation and visualization of mouse placental hematopoietic stem cells. Curr. Protoc. Stem Cell Biol. 2.2A, 8.1-8.14 (2008).
    • (2008) Curr. Protoc. Stem Cell Biol. , vol.2 , Issue.2 , pp. 81-814
    • Gekas, C.1    Rhodes, K.E.2    Mikkola, H.K.3
  • 53
    • 37549030450 scopus 로고    scopus 로고
    • Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state
    • Ginhoux, F. et al. Blood-derived dermal langerin+ dendritic cells survey the skin in the steady state. J. Exp. Med. 204, 3133-3146 (2007).
    • (2007) J. Exp. Med. , vol.204 , pp. 3133-3146
    • Ginhoux, F.1
  • 54
    • 84865410793 scopus 로고    scopus 로고
    • Optimized protocol for the isolation of spleen-resident murine neutrophils
    • Coquery, C.M., Loo, W., Buszko, M., Lannigan, J. & Erickson, L.D. Optimized protocol for the isolation of spleen-resident murine neutrophils. Cytometry A 81, 806-814 (2012).
    • (2012) Cytometry A , vol.81 , pp. 806-814
    • Coquery, C.M.1    Loo, W.2    Buszko, M.3    Lannigan, J.4    Erickson, L.D.5
  • 55
    • 84874223419 scopus 로고    scopus 로고
    • CD4+ Foxp3+ regulatory T cells prolong drug-induced disease remission in (NZBxNZW) F1 lupus mice
    • Weigert, O. et al. CD4+ Foxp3+ regulatory T cells prolong drug-induced disease remission in (NZBxNZW) F1 lupus mice. Arthritis Res. Ther. 15, R35 (2013).
    • (2013) Arthritis Res. Ther. , vol.15
    • Weigert, O.1
  • 56
    • 0036469299 scopus 로고    scopus 로고
    • Proteolipid promoter activity distinguishes two populations of NG2-positive cells throughout neonatal cortical development
    • Mallon, B.S., Shick, H.E., Kidd, G.J. & Macklin, W.B. Proteolipid promoter activity distinguishes two populations of NG2-positive cells throughout neonatal cortical development. J. Neurosci. 22, 876-885 (2002).
    • (2002) J. Neurosci. , vol.22 , pp. 876-885
    • Mallon, B.S.1    Shick, H.E.2    Kidd, G.J.3    MacKlin, W.B.4
  • 57
    • 77649131914 scopus 로고    scopus 로고
    • CXCR2-positive neutrophils are essential for cuprizone-induced demyelination: Relevance to multiple sclerosis
    • Liu, L. et al. CXCR2-positive neutrophils are essential for cuprizone-induced demyelination: relevance to multiple sclerosis. Nat. Neurosci. 13, 319-326 (2010).
    • (2010) Nat. Neurosci. , vol.13 , pp. 319-326
    • Liu, L.1
  • 58
    • 78650466243 scopus 로고    scopus 로고
    • A tissue-specific atlas of mouse protein phosphorylation and expression
    • Huttlin, E.L. et al. A tissue-specific atlas of mouse protein phosphorylation and expression. Cell 143, 1174-1189 (2010).
    • (2010) Cell , vol.143 , pp. 1174-1189
    • Huttlin, E.L.1
  • 59
    • 80155124832 scopus 로고    scopus 로고
    • MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics
    • Ting, L., Rad, R., Gygi, S.P. & Haas, W. MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics. Nat. Methods 8, 937-940 (2011).
    • (2011) Nat. Methods , vol.8 , pp. 937-940
    • Ting, L.1    Rad, R.2    Gygi, S.P.3    Haas, W.4
  • 60
    • 33847630405 scopus 로고    scopus 로고
    • Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry
    • Elias, J.E. & Gygi, S.P. Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry. Nat. Methods 4, 207-214 (2007).
    • (2007) Nat. Methods , vol.4 , pp. 207-214
    • Elias, J.E.1    Gygi, S.P.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.