Differential regulation of IL-12 and IL-10 gene expression in macrophages by the basic leucine zipper transcription factor c-Maf fibrosarcoma

Journal of Immunology

Volumn 169, Issue 10, 2002, Pages 5715-5725

  Cao, Shanjin ^a   Liu, Jianguo ^a   Chesi, Marta ^a   Bergsagel, Peter Leif ^a   Ho, I Cheng ^a   Donnelly, Raymond P ^a   Ma, Xiaojing ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE RIBOSYLATION FACTOR; ADENOVIRUS VECTOR; CHEMOKINE RECEPTOR CCR2; COMPLEMENTARY DNA; CYTOKINE; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; GLUTAREDOXIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 12; LEUCINE ZIPPER PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; RECOMBINANT COLONY STIMULATING FACTOR 1; RECOMBINANT GAMMA INTERFERON; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

ANIMAL MODEL; ARTICLE; C MAF GENE; DNA MICROARRAY; ENZYME LINKED IMMUNOSORBENT ASSAY; FIBROSARCOMA; GENE; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENOTYPE; HUMAN; HUMAN CELL; KNOCKOUT MOUSE; MACROPHAGE; MONOCYTE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DNA BINDING; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; TRANSCRIPTION REGULATION;

EID: 0037111372     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.169.10.5715     Document Type: Article

References (46)

1. Trinchieri, G. 1998. Interleukin-12: A cytokine at the interface of inflammation and immunity. Adv. Immunol. 70:83.
2. Trinchieri, G., and P. Scott. 1999. Interleukin-12: Basic principles and clinical applications. Curr. Top. Microbiol. Immunol. 238:57.
3. Aste-Amezaga, M., X. Ma, A. Sartori, and G. Trinchieri. 1998. Molecular mechanisms of the induction of IL-12 and its inhibition by IL-10. J. Immunol. 160: 5936.
4. Blank, V., and N. C. Andrews. 1997. The Maf transcription factors: Regulators of differentiation. Trends Biochem. Sci. 22:437.
5. Chesi, M., P. L. Bergsagel, O. O. Shonukan, M. L. Martelli, L. A. Brents, T. Chen, E. Schrock, T. Ried, and W. M. Kuehl. 1998. Frequent dysregulation of the c-maf proto-oncogene at 16q23 by translocation to an Ig locus in multiple myeloma. Blood 91:4457.
6. Chesi, M., W. M. Kuehl, and P. L. Bergsagel. 2000. Recurrent immunoglobulin gene translocations identify distinct molecular subtypes of myeloma. Ann. Oncol. 11:131.
7. Kim, J. I., T. Li, I. C. Ho, M. J. Grusby, and L. H. Glimcher. 1999. Requirement for the c-Maf transcription factor in crystallin gene regulation and lens development. Proc. Natl. Acad. Sci. USA 96:3781.
8. Kawauchi, S., S. Takahashi, O. Nakajima, H. Ogino, M. Morita, M. Nishizawa, K. Yasuda, and M. Yamamoto. 1999. Regulation of lens fiber cell differentiation by transcription factor c-Maf. J. Biol. Chem. 274:19254.
9. Ring, B. Z., S. P. Cordes, P. A. Overbeek, and G. S. Barsh. 2000. Regulation of mouse lens fiber cell development and differentiation by the Maf gene. Development 127:307
10. Kim, I. I., I. C. Ho, M. J. Grusby, and L. H. Glimcher. 1999. The transcription factor c-Maf controls the production of interleukin-4 but not other Th2 cytokines. Immunity 10:745.
11. Ma, X., J. M. Chow, G. Gri, G. Carra, F. Gerosa, S. F. Wolf, R. Dzialo, and G. Trinchieri. 1996. The interleukin 12 p40 gene promoter is primed by interferon γ in monocytic cells. J. Exp. Med. 183:147.
12. Gri, G., D. Savio, G. Trinchieri, and X. Ma. 1998. Synergistic regulation of the human interleukin-12 p40 promoter by NFκB and Ets transcription factors in Epstein-Barr virus-transformed B cells and macrophages. J. Biol. Chem. 273:6431.
13. Grazia Cappiello, M., F. S. Sutterwala, G. Trinchieri, D. M. Mosser, and X. Ma. 2001. Suppression of II-12 transcription in macrophages following Fcγ receptor ligation. J. Immunol. 166:4498.
14. Ho, I. C., M. R. Hodge, J. W. Rooney, and L. H. Glimcher. 1996. The protooncogene c-maf is responsible for tissue-specific expression of interleukin-4. Cell 85:973.
15. Chesi, M., L. A. Brents, S. A. Ely, C. Bais, D. F. Robbiani, E. A. Mesri, W. M. Kuehl, and P. L. Bergsagel. 2001. Activated fibroblast growth factor receptor 3 is an oncogene that contributes to tumor progression in multiple myeloma. Blood 97:729.
16. Cepko, C. 2001. Preparation of a specific retrovirus producer cell line. In Current Protocols in Molecular Biology, Vol. 2. F. M. Ausubel, R. E. Kingston, D. D. Moore, J. G. Seidma, J. A. Smith, K. Struhl, eds. Wiley, p. 9.10.9.
17. Schreiber, E., P. Matthias, M. M. Muller, and W. Schaffner. 1989. Rapid detection of octamer binding proteins with "mini-extracts", prepared from a small number of cells. Nucleic Acids Res. 17:6419.
18. Ma, X., M. Neurath, G. Gri, and G. Trinchieri. 1997. Identification and characterization of a novel Ets-2-related nuclear complex implicated in the activation of the human interleukin-12 p40 gene promoter. J. Biol. Chem. 272:10389.
19. Lichanska, A. M., and D. A. Hume. 2000. Origins and functions of phagocytes in the embryo. Exp. Hematol. 28:601.
20. D'Amico, G., G. Frascaroli, G. Bianchi, P. Transidico, A. Doni, A. Vecchi, S. Sozzani, P. Allavena, and A. Mantovani. 2000. Uncoupling of inflammatory chemokine receptors by IL-10: Generation of functional decoys. Nat. Immunol. 1:387.
21. Nakamura, H., J. Vaage, G. Valen, C. A. Padilla, M. Bjornstedt, and A. Holmgren. 1998. Measurements of plasma glutaredoxin and thioredoxin in healthy volunteers and during open-heart surgery. Free Radic. Biol. Med. 24: 1176.
22. Nath, K. A., G. M. Vercellotti, J. P. Grande, H. Miyoshi, C. V. Paya, J. C. Manivel, J. J. Haggard, A. J. Croatt, W. D. Payne, and J. Alam. 2001. Heme protein-induced chronic renal inflammation: Suppressive effect of induced heme oxygenase-1. Kidney Int. 59:106.
23. Rauschmayr, T., R. W. Groves, and T. S. Kupper. 1997. Keratinocyte expression of the type 2 interleukin 1 receptor mediates local and specific inhibition of interleukin 1-mediated inflammation. Proc. Natl. Acad. Sci. USA 94:5814.
24. Behrens, A., K. Sabapathy, I. Graef, M. Cleary, G. R. Crabtree, and E. F. Wagner. 2001. Jun N-terminal kinase 2 modulates thymocyte apoptosis and T cell activation through c-Jun and nuclear factor of activated T cell (NF-AT). Proc. Natl. Acad. Sci. USA 98:1769.
25. Chen, N., M. Nomura, Q. B. She, W. Y. Ma, A. M. Bode, L. Wang, R. A. Flavell, and Z. Dong. 2001. Suppression of skin tumorigenesis in c-Jun NH(2)-terminal kinase-2-deficient mice. Cancer Res. 61:3908.
26. Song, G. Y., C. S. Chung, D. Jarrar, I. H. Chaudry, and A. Ayala. 2001. Evolution of an immune suppressive macrophage phenotype as a product of P38 MAPK activation in polymicrobial sepsis. Shock 15:42.
27. Wang, I. M., C. Contursi, A. Masumi, X. Ma, G. Trinchieri, and K. Ozato. 2000. An IFN-γ-inducible transcription factor, IFN consensus sequence binding protein (ICSBP), stimulates IL-12 p40 expression in macrophages. J. Immunol. 165:271.
28. Murphy, T. L., M. G. Cleveland, P. Kulesza, J. Magram, and K. M. Murphy. 1995. Regulation of interleukin 12 p40 expression through an NF-κB half-site. Mol. Cell. Biol. 15:5258.
29. Sanjabi, S., A. Hoffmann, H. C. Liou, D. Baltimore, and S. T. Smale. 2000. Selective requirement for c-Re1 during IL-12 P40 gene induction in macrophages. Proc. Natl. Acad. Sci. USA 97:12705.
30. Weinmann, A. S., D. M. Mitchell, S. Sanjabi, M. N. Bradley, A. Hoffmann, H. C. Liou, and S. T. Smale. 2001. Nucleosome remodeling at the IL-12 p40 promoter is a TLR-dependent, Re1-independent event. Nat. Immunol. 2:51.
31. Plevy, S. E., J. H. Gemberling, S. Hsu, A. J. Dorner, and S. T. Smale. 1997. Multiple control elements mediate activation of the murine and human interleukin 12 p40 promoters: Evidence of functional synergy between C/EBP and Re1 proteins. Mol. Cell. Biol. 17:4572.
32. Becker, C., S. Wirtz, X. Ma, M. Blessing, P. R. Galle, and M. F. Neurath. 2001. Regulation of IL-12 p40 promoter activity in primary human monocytes: Roles of NF-κB, CCAAT/enhancer-binding protein β, and PU.1 and identification of a novel repressor element (GA-12) that responds to IL-4 and prostaglandin E(2). J. Immunol. 167:2608.
33. Zhu, C., K. Gagnidze, J. H. Gemberling, and S. E. Plevy. 2001. Characterization of an activation protein-1-binding site in the murine interleukin-12 p40 promoter: Demonstration of novel functional elements by a reductionist approach. J. Biol. Chem. 276:18519.
34. Hegde, S. P., A. Kumar, C. Kurschner, and L. H. Shapiro. 1998. c-Maf interacts with c-Myb to regulate transcription of an early myeloid gene during differentiation. Mol. Cell. Biol. 18:2729.
35. Liu, B., J. Liao, X. Rao, S. A. Kushner, C. D. Chung, D. D. Chang, and K. Shuai. 1998. Inhibition of Stat1-mediated gene activation by PIASI. Proc. Natl. Acad. Sci. USA 95:10626.
36. Otterbein, L. E., F. H. Bach, J. Alam, M. Soares, H. Tao Lu, M. Wysk, R. J. Davis, R. A. Flavell, and A. M. Choi. 2000. Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway. Nat. Med. 6:422.
37. Igarashi, K., K. Kataoka, K. Itoh, N. Hayashi, M. Nishizawa, and M. Yamamoto. 1994. Regulation of transcription by dimerization of erythroid factor NF-E2 p45 with small Maf proteins. Nature 367:568.
38. Kataoka, K., K. T. Fujiwara, M. Noda, and M. Nishizawa. 1994. MafB, a new Maf family transcription activator that can associate with Maf and Fos but not with Jun. Mol. Cell. Biol. 14:7581.
39. Kataoka, K., M. Noda, and M. Nishizawa. 1994. Maf nuclear oncoprotein recognizes sequences related to an AP-1 site and forms heterodimers with both Fos and Jun. Mol. Cell. Biol. 14:700.
40. Kerppola, T. K., and T. Curran. 1994. Maf and Nr1 can bind to AP-1 sites and form heterodimers with Fos and Jun. Oncogene 9:675.
41. Kerppola, T. K., and T. Curran. 1994. A conserved region adjacent to the basic domain is required for recognition of an extended DNA binding site by Maf/Nr1 family proteins. Oncogene 9:3149.
42. Kataoka, K., K. Igarashi, K. Itoh, K. T. Fujiwara, M. Noda, M. Yamamoto, and M. Nishizawa. 1995. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor. Mol. Cell. Biol. 15: 2180.
43. Kurschner, C., and J. I. Morgan. 1995. The maf proto-oncogene stimulates transcription from multiple sites in a promoter that directs Purkinje neuron-specific gene expression. Mol. Cell. Biol. 15:246.
44. Kataoka, K., M. Noda, and M. Nishizawa. 1996. Transactivation activity of Maf nuclear oncoprotein is modulated by Jun, Fos and small Maf proteins. Oncogene 12:53.
45. Sieweke, M. H., H. Tekotte, J. Frampton, and T. Graf. 1996. MafB is an interaction partner and repressor of Ets-1 that inhibits erythroid differentiation. Cell 85:49.
46. Seppanen, M., T. Henttinen, L. Lin, J. Punnonen, S. Grenman, R. Punnonen, and K. K. Vihko. 1998. Inhibitory effects of cytokines on ovarian and endometrial carcinoma cells in vitro with special reference to induction of specific transcriptional regulators. Oncol. Res. 10:575.