Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

Nature Genetics

Volumn 45, Issue 11, 2013, Pages 1353-1362

  Beecham, Ashley H ^a   Patsopoulos, Nikolaos A ^b,c,d,e   Xifara, Dionysia K ^f   Davis, Mary F ^g   Kemppinen, Anu ^h   Cotsapas, Chris ^e,i   Shah, Tejas S ^j   Spencer, Chris ^f   Booth, David ^k   Goris, An ^l   Oturai, Annette ^m   Saarela, Janna ⁿ   Fontaine, Bertrand ^o   Hemmer, Bernhard ^p,q,r   Martin, Claes ^s   Zipp, Frauke ^t   D'Alfonso, Sandra ^u   Martinelli Boneschi, Filippo ^v   Taylor, Bruce ^w   Harbo, Hanne F ^x,y   Kockum, Ingrid ^z   Hillert, Jan ^z   Olsson, Tomas ^z   Ban, Maria ^h   Oksenberg, Jorge R ^aa   Hintzen, Rogier ^ab   Barcellos, Lisa F ^ac,ad,ae   Agliardi, Cristina ^af   Alfredsson, Lars ^z   Alizadeh, Mehdi ^ag   Anderson, Carl ^j   Andrews, Robert ^j   Søndergaard, Helle Bach ^m   Baker, Amie ^h   Band, Gavin ^f   Baranzini, Sergio E ^aa   Barizzone, Nadia ^u   Barrett, Jeffrey ^j   Bellenguez, Céline ^f   Bergamaschi, Laura ^u   Bernardinelli, Luisa ^ah   Berthele, Achim ^p   Biberacher, Viola ^p   Binder, Thomas M C ^ai   Blackburn, Hannah ^j   Bomfim, Izaura L ^z   Brambilla, Paola ^v   Broadley, Simon ^aj   Brochet, Bruno ^ak   Brundin, Lou ^z   Buck, Dorothea ^p   Butzkueven, Helmut ^al,am   Caillier, Stacy J ^aa   Camu, William ^an   Carpentier, Wassila ^ao   Cavalla, Paola ^ap,aq   Celius, Elisabeth G ^x   Coman, Irène ^ar   Comi, Giancarlo ^v   Corrado, Lucia ^u   Cosemans, Leentje ^l   Cournu Rebeix, Isabelle ^o   Cree, Bruce A C ^aa   Cusi, Daniele ^as   Damotte, Vincent ^o   Defer, Gilles ^at   Delgado, Silvia R ^a   Deloukas, Panos ^j   Di Sapio, Alessia ^au   Dilthey, Alexander T ^f   Donnelly, Peter ^f   Dubois, Bénédicte ^l   Duddy, Martin ^av   Edkins, Sarah ^j   Elovaara, Irina ^aw   Esposito, Federica ^v   Evangelou, Nikos ^ax   Fiddes, Barnaby ^h   Field, Judith ^al   Franke, Andre ^ay   Freeman, Colin ^f   Frohlich, Irene Y ^b   Galimberti, Daniela ^az,ba   Gieger, Christian ^bb   Gourraud, Pierre Antoine ^aa   Graetz, Christiane ^t   Graham, Andrew ^bc   Grummel, Verena ^p   Guaschino, Clara ^v   Hadjixenofontos, Athena ^a   Hakonarson, Hakon ^bd,be   Halfpenny, Christopher ^bf   Hall, Gillian ^bg   Hall, Per ^z   Hamsten, Anders ^bh   Harley, James ^bi   Harrower, Timothy ^bj   Hawkins, Clive ^bk   Hellenthal, Garrett ^bl   Hillier, Charles ^bm   Hobart, Jeremy ^bn   Hoshi, Muni ^p   Hunt, Sarah E ^j   Jagodic, Maja ^z   Jelcic, Ilijas ^ai,bo   Jochim, Angela ^p   Kendall, Brian ^bp   Kermode, Allan ^bq,br   Kilpatrick, Trevor ^bs   Koivisto, Keijo ^bt   Konidari, Ioanna ^a   Korn, Thomas ^p   Kronsbein, Helena ^p   Langford, Cordelia ^j   Larsson, Malin ^bu   Lathrop, Mark ^bv,bw,bx   Lebrun Frenay, Christine ^by   Lechner Scott, Jeannette ^bz   Lee, Michelle H ^b   Leone, Maurizio A ^ca   Leppä, Virpi ⁿ   Liberatore, Giuseppe ^v   Lie, Benedicte A ^x,y   Lill, Christina M ^t,cb   Lindén, Magdalena ^z   Link, Jenny ^z   Luessi, Felix ^t   Lycke, Jan ^cc   Macciardi, Fabio ^az,cd   Männistö, Satu ^ce   Manrique, Clara P ^a   Martin, Roland ^ai,bo   Martinelli, Vittorio ^v   Mason, Deborah ^cf   Mazibrada, Gordon ^cg   McCabe, Cristin ^e   Mero, Inger Lise ^x,y   Mescheriakova, Julia ^ab   Moutsianas, Loukas ^f   Myhr, Kjell Morten ^ch   Nagels, Guy ^ci   Nicholas, Richard ^cj   Nilsson, Petra ^ck   Piehl, Fredrik ^z   Pirinen, Matti ^f   Price, Siân E ^cl   Quach, Hong ^ac   Reunanen, Mauri ^cm,cn   Robberecht, Wim ^l,co,cp   Robertson, Neil P ^cq   Rodegher, Mariaemma ^v   Rog, David ^cr   Salvetti, Marco ^cs   Schnetz Boutaud, Nathalie C ^g   Sellebjerg, Finn ^m   Selter, Rebecca C ^p   Schaefer, Catherine ^ae   Shaunak, Sandip ^ct   Shen, Ling ^ae   Shields, Simon ^cu   Siffrin, Volker ^t   Slee, Mark ^cv   Sorensen, Per Soelberg ^m   Sorosina, Melissa ^v   Sospedra, Mireia ^ai,bo   Spurkland, Anne ^y   Strange, Amy ^f   Sundqvist, Emilie ^z   Thijs, Vincent ^l,co,cp   Thorpe, John ^cw   Ticca, Anna ^cx   Tienari, Pentti ^cy   Van Duijn, Cornelia ^ab   Visser, Elizabeth M ^cz   Vucic, Steve ^k   Westerlind, Helga ^z   Wiley, James S ^al   Wilkins, Alastair ^da   Wilson, James F ^db   Winkelmann, Juliane ^p,q,bb,dc   Zajicek, John ^bn   Zindler, Eva ^t   Haines, Jonathan L ^g   Pericak Vance, Margaret A ^a   Ivinson, Adrian J ^dd   Stewart, Graeme ^k   Hafler, David ^e,i   Hauser, Stephen L ^aa   Compston, Alastair ^h   McVean, Gil ^f   De Jager, Philip ^b,d,e   Sawcer, Stephen J ^h   McCauley, Jacob L ^a   more..

^a UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF CAMBRIDGE   (United Kingdom)

ⁱ YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^j WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^k UNIVERSITY OF SYDNEY   (Australia)

^l UNIVERSITY OF LEUVEN   (Belgium)

^m Mental Health Services CPH   (Denmark)

ⁿ UNIVERSITY OF HELSINKI   (Finland)

^o INSTITUT DU CERVEAU ET DE LA MOELLE ÉPINIÈRE   (France)

^p TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^q Germany 3 Munich Cluster for Systems Neurology   (Germany)

^r German Competence Network Multiple Sclerosis (KKNMS)   (Germany)

^s DANDERYD HOSPITAL   (Sweden)

^t UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

^u UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^v SAN RAFFAELE HOSPITAL   (Italy)

^w UNIVERSITY OF TASMANIA   (Australia)

^x ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^y UNIVERSITY OF OSLO   (Norway)

^z KAROLINSKA INSTITUTE   (Sweden)

^aa UNIVERSITY OF CALIFORNIA   (United States)

^ab ERASMUS MEDICAL CENTER   (Netherlands)

^ac UNIVERSITY OF CALIFORNIA   (United States)

^ad UNIVERSITY OF CALIFORNIA   (United States)

^ae DIVISION OF RESEARCH   (United States)

^af IRCCS FONDAZIONE DON CARLO GNOCCHI   (Italy)

^ag UNIVERSITÉ DE RENNES 1   (France)

^ah MRC BIOSTATISTICS UNIT   (United Kingdom)

^ai UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^aj GRIFFITH UNIVERSITY   (Australia)

^ak BORDEAUX UNIVERSITY HOSPITAL   (France)

^al UNIVERSITY OF MELBOURNE   (Australia)

^am MONASH UNIVERSITY   (Australia)

^an MONTPELLIER UNIVERSITY HOSPITAL   (France)

^ao SORBONNE UNIVERSITÉ   (France)

^ap CITTÀ DELLA SALUTE E DELLA SCIENZA HOSPITAL   (Italy)

^aq UNIVERSITY OF TURIN   (Italy)

^ar AVICENNE HOSPITAL   (France)

^as UNIVERSITY OF MILAN   (Italy)

^at CAEN UNIVERSITY HOSPITAL   (France)

^au SAN LUIGI GONZAGA UNIVERSITY HOSPITAL   (Italy)

^av ROYAL VICTORIA INFIRMARY   (United Kingdom)

^aw TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^ax NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST   (United Kingdom)

^ay UNIVERSITY OF KIEL   (Germany)

^az UNIVERSITY OF MILAN   (Italy)

^ba FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^bb INSTITUTE OF EPIDEMIOLOGY   (Germany)

^bc IPSWICH HOSPITAL NHS TRUST   (United Kingdom)

^bd CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^be UNIVERSITY OF PENNSYLVANIA   (United States)

^bf SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^bg ABERDEEN ROYAL INFIRMARY   (United Kingdom)

^bh KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^bi HULL ROYAL INFIRMARY   (United Kingdom)

^bj ROYAL DEVON AND EXETER NHS FOUNDATION TRUST   (United Kingdom)

^bk KEELE UNIVERSITY SCHOOL OF MEDICINE   (United Kingdom)

^bl UNIVERSITY COLLEGE LONDON   (United Kingdom)

^bm POOLE HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

^bn PLYMOUTH UNIVERSITY PENINSULA SCHOOLS OF MEDICINE AND DENTISTRY   (United Kingdom)

^bo UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^bp LEICESTER ROYAL INFIRMARY   (United Kingdom)

^bq UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^br MURDOCH UNIVERSITY   (Australia)

^bs UNIVERSITY OF MELBOURNE   (Australia)

^bt SEINÄJOKI CENTRAL HOSPITAL   (Finland)

^bu LINKÖPING UNIVERSITY   (Sweden)

^bv FONDATION JEAN DAUSSET CEPH   (France)

^bw CENTRE NATIONAL DE GÉNOTYPAGE   (France)

^bx MCGILL UNIVERSITY   (Canada)

^by PASTEUR HOSPITAL   (France)

^bz HUNTER MEDICAL RESEARCH INSTITUTE   (Australia)

^ca MAGGIORE DELLA CARITÀ HOSPITAL   (Italy)

^cb MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

^cc UNIVERSITY OF GOTHENBURG   (Sweden)

^cd UNIVERSITY OF CALIFORNIA   (United States)

^ce NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^cf CANTERBURY DISTRICT HEALTH BOARD   (New Zealand)

^cg QUEEN ELIZABETH HOSPITAL   (United Kingdom)

^ch HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^ci National Multiple Sclerosis Center   (Belgium)

^cj CHARING CROSS HOSPITAL   (United Kingdom)

^ck LUND UNIVERSITY   (Sweden)

^cl ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

^cm UNIVERSITY OF OULU   (Finland)

^cn OULU UNIVERSITY HOSPITAL   (Finland)

^co Vesalius Research Center   (Belgium)

^cp UNIVERSITY HOSPITALS LEUVEN   (Belgium)

^cq CARDIFF UNIVERSITY   (United Kingdom)

^cr SALFORD ROYAL NHS FOUNDATION TRUST   (United Kingdom)

^cs SAPIENZA UNIVERSITY OF ROME   (Italy)

^ct ROYAL PRESTON HOSPITAL   (United Kingdom)

^cu NORFOLK AND NORWICH HOSPITAL   (United Kingdom)

^cv FLINDERS UNIVERSITY   (Australia)

^cw PETERBOROUGH CITY HOSPITAL   (United Kingdom)

^cx SAN FRANCESCO HOSPITAL   (Italy)

^cy HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^cz UNIVERSITY OF ABERDEEN   (United Kingdom)

^da UNIVERSITY OF BRISTOL   (United Kingdom)

^db UNIVERSITY OF EDINBURGH   (United Kingdom)

^dc TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^dd The Harvard Center for Neurodegeneration & Repair   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

CD6 ANTIGEN; HERPESVIRUS ENTRY MEDIATOR LIGAND; LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 3; STAT4 PROTEIN;

BAYES THEOREM; CD58 GENE; CD6 GENE; CONTROLLED STUDY; EUROPE; GENE; GENE LOCUS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HUMAN; IL12A GENE; IL2RA GENE; LETTER; MAJOR CLINICAL STUDY; MAJOR HISTOCOMPATIBILITY COMPLEX; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; STAT4 GENE; TNFAIP3 GENE; TNFRSF1A GENE; TNFSF14 GENE;

EID: 84887058596     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.2770     Document Type: Article

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