Notch-RBP-J signaling regulates the transcription factor IRF8 to promote inflammatory macrophage polarization

Nature Immunology

Volumn 13, Issue 7, 2012, Pages 642-650

  Xu, Haixia ^a,b   Zhu, Jimmy ^a   Smith, Sinead ^a   Foldi, Julia ^c   Zhao, Baohong ^a   Chung, Allen Y ^a   Outtz, Hasina ^d   Kitajewski, Jan ^d   Shi, Chao ^c,e   Weber, Silvio ^f   Saftig, Paul ^f   Li, Yueming ^e   Ozato, Keiko ^g   Blobel, Carl P ^a   Ivashkiv, Lionel B ^a,c   Hu, Xiaoyu ^a,h  

^a HOSPITAL FOR SPECIAL SURGERY   (United States)

^b SUN YAT SEN UNIVERSITY   (China)

^c Weill Cornell Graduate School of Biomedical Sciences   (United States)

^d Och Spine at New York Presbyterian Hospitals   (United States)

^e MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^f UNIVERSITY OF KIEL   (Germany)

^g EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^h WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA BINDING PROTEIN; INITIATION FACTOR 4E; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 2; MNK1 PROTEIN; NOTCH RECEPTOR; PROTEIN KINASE; RBP J PROTEIN; TOLL LIKE RECEPTOR 4; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; GENE EXPRESSION REGULATION; GENE INDUCTION; IMMUNOREGULATION; INFLAMMATORY CELL; INNATE IMMUNITY; LISTERIA MONOCYTOGENES; MACROPHAGE; MOUSE; NONHUMAN; POLARIZATION; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; TRANSLATION INITIATION;

ANIMALS; CELL POLARITY; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION REGULATION; IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE-BINDING PROTEIN; INFLAMMATION; INTERFERON REGULATORY FACTORS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; LISTERIOSIS; MACROPHAGE ACTIVATION; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 4; TRANSCRIPTION FACTORS;

EID: 84862591151     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2304     Document Type: Article

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