Unfolding novel mechanisms of polyphenol flavonoids for better glycaemic control: Targeting pancreatic islet amyloid polypeptide (IAPP)

Nutrients

Volumn 9, Issue 7, 2017, Pages

  Sequeira, Ivana R ^a,b   Poppitt, Sally D ^a,b,c  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b National Science Challenge   (New Zealand)

^c UNIVERSITY OF AUCKLAND   (New Zealand)

Author keywords

Amyloidogenesis; Antioxidant; Flavonoids; Insulin resistance; Islet amyloid polypeptide (IAPP); Polyphenols; Protein misfolding disease (PMD); Quercetin O rutinoside; Rutin; Type 2 diabetes; cell dysfunction

Indexed keywords

AMYLIN; FLAVONOID; GLUCOCORTICOID; POLYPHENOL DERIVATIVE; QUERCETIN; REACTIVE OXYGEN METABOLITE; RUTOSIDE; AMYLOID; INSULIN; POLYPHENOL;

AMYLOIDOSIS; ANTIOXIDANT ACTIVITY; APOPTOSIS; DEGENERATIVE DISEASE; DIETARY INTAKE; DRUG EFFICACY; GLYCEMIC CONTROL; HUMAN; HYDROGEN BOND; HYPERGLYCEMIA; INSULIN RELEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS DISEASE; PANCREAS ISLET BETA CELL; PHYTOCHEMISTRY; PROTEIN AGGREGATION; PROTEIN MISFOLDING; REVIEW; UBIQUITINATION; ANIMAL; ANIMAL MODEL; BLOOD; DRUG EFFECT; GLUCOSE BLOOD LEVEL; METABOLISM; PANCREAS ISLET; RANDOMIZED CONTROLLED TRIAL (TOPIC); SECRETION (PROCESS);

AMYLOID; AMYLOIDOSIS; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; HUMANS; HYPERGLYCEMIA; INSULIN; INSULIN-SECRETING CELLS; ISLET AMYLOID POLYPEPTIDE; ISLETS OF LANGERHANS; MODELS, ANIMAL; POLYPHENOLS; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 85025830575     PISSN: None     EISSN: 20726643     Source Type: Journal    
DOI: 10.3390/nu9070788     Document Type: Review

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