Calcium-activated calpain-2 is a mediator of beta cell dysfunction and apoptosis in type 2 diabetes

Journal of Biological Chemistry

Volumn 285, Issue 1, 2010, Pages 339-348

  Huang, Chang Jiang ^a   Gurlo, Tatyana ^a   Haataja, Leena ^a,c   Costes, Safia ^a   Daval, Marie ^a   Ryazantsev, Sergey ^b   Wu, Xiuji ^a   Butler, Alexandr E ^a   Butler, Peter C ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; BETA CELL; CALPAINS; CELL DYSFUNCTION; CYTOSOLIC; DEGENERATIVE DISEASE; HUMAN ISLETS; HYPERACTIVATION; INSULINOMA CELLS; NEURODEGENERATIVE DISEASE; OVER-EXPRESSION; SPECTRIN; TYPE-2 DIABETES;

CALCIUM; OLIGOMERS;

CELL DEATH;

CALPAIN 2; CASPASE 3;

ADULT; AGED; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL ISOLATION; CELL VIABILITY; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOSKELETON; CYTOTOXICITY; ENZYME ACTIVITY; FEMALE; GENE ACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPHOCYTE ACTIVATION; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

ADULT; AGED; AGED, 80 AND OVER; AMYLOID; ANIMALS; APOPTOSIS; CALCIUM; CALPAIN; CELL LINE, TUMOR; CELL SURVIVAL; CYTOSOL; DIABETES MELLITUS, TYPE 2; DIPEPTIDES; ENZYME ACTIVATION; FEMALE; HUMANS; INSULIN-SECRETING CELLS; MALE; MIDDLE AGED; PROTEIN TRANSPORT; RATS; RECOMBINANT FUSION PROTEINS; SPECTRIN;

RATTUS;

EID: 73649114570     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.024190     Document Type: Article

References (56)

1. Weyer, C., Bogardus, C., Mott, D. M., and Pratley, R. E. (1999) J. Clin. Invest. 104, 787-794
2. Haataja, L., Gurlo, T., Huang, C. J., and Butler, P. C. (2008) Endocr. Rev. 29, 303-316
3. Butler, A. E., Janson, J., Bonner-Weir, S., Ritzel, R., Rizza, R. A., and Butler, P. C. (2003) Diabetes 52, 102-110
4. Hardy, J., and Selkoe, D. J. (2002) Science 297, 353-356
5. Lue, L. F., Kuo, Y. M., Roher, A. E., Brachova, L., Shen, Y., Sue, L., Beach, T., Kurth, J. H., Rydel, R. E., and Rogers, J. (1999) Am. J. Pathol. 155, 853-862
6. Janson, J., Soeller, W. C., Roche, P. C., Nelson, R. T., Torchia, A. J., Kreutter, D. K., and Butler, P. C. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 7283-7288
7. Janson, J., Ashley, R. H., Harrison, D., McIntyre, S., and Butler, P. C. (1999) Diabetes 48, 491-498
8. Chartier-Harlin, M. C., Crawford, F., Houlden, H., Warren, A., Hughes, D., Fidani, L., Goate, A., Rossor, M., Roques, P., Hardy, J., et al. (1991) Nature 353, 844-846
9. Matveyenko, A. V., and Butler, P. C. (2006) Ilar J. 47, 225-233
10. Sparr, E., Engel, M. F., Sakharov, D. V., Sprong, M., Jacobs, J., de Kruijff, B., Höppener, J. W., and Killian, J. A. (2004) FEBS Lett. 577, 117-120
11. Jayasinghe, S. A., and Langen, R. (2007) Biochim. Biophys. Acta 1768, 2002-2009
12. Huang, C. J., Haataja, L., Gurlo, T., Butler, A. E., Wu, X., Soeller, W. C., and Butler, P. C. (2007) Am. J. Physiol. Endocrinol. Metab. 293, E1656-E1662
13. Huang, C. J., Lin, C. Y., Haataja, L., Gurlo, T., Butler, A. E., Rizza, R. A., and Butler, P. C. (2007) Diabetes 56, 2016-2027
14. Lin, C. Y., Gurlo, T., Kayed, R., Butler, A. E., Haataja, L., Glabe, C. G., and Butler, P. C. (2007) Diabetes 56, 1324-1332
15. Gurlo, T., Ryazantsev, S., Huang, C. J., Yeh, M. W., Reber, H. A., Hines, O. J., O'Brien, T., Glabe, C. G., and Butler, P. C. (2010) Am. J. Pathol.,
16. Saito, K., Elce, J. S., Hamos, J. E., and Nixon, R. A. (1993) Proc. Natl. Acad. Sci. U.S.A. 90, 2628-2632
17. Bevers, M. B., and Neumar, R. W. (2008) J. Cereb. Blood Flow Metab. 28, 655-673
18. Demuro, A., Mina, E., Kayed, R., Milton, S. C., Parker, I., and Glabe, C. G. (2005) J. Biol. Chem. 280, 17294-17300
19. Kuwako, K., Nishimura, I., Uetsuki, T., Saido, T. C., and Yoshikawa, K. (2002) Brain Res. Mol. Brain Res. 107, 166-175
20. Norberg, E., Gogvadze, V., Ott, M., Horn, M., Uhlén, P., Orrenius, S., and Zhivotovsky, B. (2008) Cell Death Differ. 15, 1857-1864
21. Song, Y., You, N. C., Hsu, Y. H., Sul, J., Wang, L., Tinker, L., Eaton, C. B., and Liu, S. (2007) Hum. Mol. Genet 16, 2960-2971
22. Wu, H. Y., and Lynch, D. R. (2006) Mol. Neurobiol. 33, 215-236
23. Hohmeier, H. E., Mulder, H., Chen, G., Henkel-Rieger, R., Prentki, M., and Newgard, C. B. (2000) Diabetes 49, 424-430
24. Rao, A., Luo, C., and Hogan, P. G. (1997) Annu. Rev. Immunol. 15, 707-747
25. Young, S. H., Ennes, H. S., McRoberts, J. A., Chaban, V. V., Dea, S. K., and Mayer, E. A. (1999) Am. J. Physiol. 276, G1204-G1212
26. Cowan, C. M., Fan, M. M., Fan, J., Shehadeh, J., Zhang, L. Y., Graham, R. K., Hayden, M. R., and Raymond, L. A. (2008) J. Neurosci. 28, 12725-12735
27. Dutta, S., Chiu, Y. C., Probert, A. W., and Wang, K. K. (2002) Biol. Chem. 383, 785-791
28. Ryazantsev, S., Yu, W. H., Zhao, H. Z., Neufeld, E. F., and Ohmi, K. (2007) Mol. Genet. Metab. 90, 393-401
29. Kayed, R., Head, E., Thompson, J. L., McIntire, T. M., Milton, S. C., Cotman, C. W., and Glabe, C. G. (2003) Science 300, 486-489
30. Saisho, Y., Manesso, E., Gurlo, T., Huang, C. J., Toffolo, G. M., Cobelli, C., and Butler, P. C. (2009) Am. J. Physiol. Endocrinol. Metab. 296, E89-E96
31. Khemtémourian, L., Killian, J. A., Höppener, J. W., and Engel, M. F. (2008) Exp. Diabetes Res. 2008, 421287
32. Engel, M. F., Khemtémourian, L., Kleijer, C. C., Meeldijk, H. J., Jacobs, J., Verkleij, A. J., de Kruijff, B., Killian, J. A., and Höppener, J. W. (2008) Proc. Natl. Acad. Sci. U.S.A. 105, 6033-6038
33. Michelangeli, F., Liprandi, F., Chemello, M. E., Ciarlet, M., and Ruiz, M. C. (1995) J. Virol. 69, 3838-3847
34. Van Coppenolle, F., Vanden Abeele, F., Slomianny, C., Flourakis, M., Hesketh, J., Dewailly, E., and Prevarskaya, N. (2004) J. Cell Sci. 117, 4135-4142
35. Paschen, W., Hotop, S., and Aufenberg, C. (2003) Cell Calcium 33, 83-89
36. Hood, J. L., Brooks, W. H., and Roszman, T. L. (2004) J. Biol. Chem. 279, 43126-43135
37. Johnson, G. V., and Guttmann, R. P. (1997) BioEssays 19, 1011-1018
38. Piwocka, K., Vejda, S., Cotter, T. G., O'Sullivan, G. C., and McKenna, S. L. (2006) Blood 107, 4003-4010
39. Pettigrew, L. C., Holtz, M. L., Craddock, S. D., Minger, S. L., Hall, N., and Geddes, J. W. (1996) J. Cereb. Blood Flow Metab. 16, 1189-1202
40. Takano, J., Tomioka, M., Tsubuki, S., Higuchi, M., Iwata, N., Itohara, S., Maki, M., and Saido, T. C. (2005) J. Biol. Chem. 280, 16175-16184
41. Giunti, R., Gamberucci, A., Fulceri, R., Bánhegyi, G., and Benedetti, A. (2007) Arch. Biochem. Biophys. 462, 115-121
42. Ferreiro, E., Oliveira, C. R., and Pereira, C. M. (2008) Neurobiol. Dis. 30, 331-342
43. Casas, S., Novials, A., Reimann, F., Gomis, R., and Gribble, F. M. (2008) Diabetologia 51, 2252-2262
44. Rardon, D. P., Cefali, D. C., Mitchell, R. D., Seiler, S. M., Hathaway, D. R., and Jones, L. R. (1990) Circ. Res. 67, 84-96
45. Nagata, E., Tanaka, K., Gomi, S., Mihara, B., Shirai, T., Nogawa, S., Nozaki, H., Mikoshiba, K., and Fukuuchi, Y. (1994) Neuroscience 61, 983-990
46. Mirzabekov, T. A., Lin, M. C., and Kagan, B. L. (1996) J. Biol. Chem. 271, 1988-1992
47. Pereira, C., Ferreiro, E., Cardoso, S. M., and de Oliveira, C. R. (2004) J. Mol. Neurosci. 23, 97-104
48. Trinchese, F., Fa', M., Liu, S., Zhang, H., Hidalgo, A., Schmidt, S. D., Yamaguchi, H., Yoshii, N., Mathews, P. M., Nixon, R. A., and Arancio, O. (2008) J. Clin. Invest. 118, 2796-2807
49. Stabach, P. R., Cianci, C. D., Glantz, S. B., Zhang, Z., and Morrow, J. S. (1997) Biochemistry 36, 57-65
50. Rajgopal, Y., and Vemuri, M. C. (2002) Neurosci. Lett. 321, 187-191
51. Siman, R., Zhang, C., Roberts, V. L., Pitts-Kiefer, A., and Neumar, R. W. (2005) J. Cereb. Blood Flow Metab. 25, 1433-1444
52. Grant, R. J., Sellings, L. H., Crocker, S. J., Melloni, E., Park, D. S., and Clarke, P. B. (2009) Neuroscience 158, 558-569
53. Epstein, P. N., Ribar, T. J., Decker, G. L., Yaney, G., and Means, A. R. (1992) Endocrinology 130, 1387-1393
54. Gómez Dumm, C. L., Atwater, I., Epstein, P. N., and Gagliardino, J. J. (1994) Virchows Arch. 425, 73-77
55. Gwiazda, K. S., Yang, T. L., Lin, Y., and Johnson, J. D. (2009) Am. J. Physiol. Endocrinol. Metab. 296, E690-E701
56. Resende, R., Ferreiro, E., Pereira, C., and Oliveira, C. R. (2008) J. Neurosci. Res. 86, 2091-2099