Spontaneous diabetes mellitus in transgenic mice expressing human islet amyloid polypeptide

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 14, 1996, Pages 7283-7288

  Janson, Juliette ^a   Soeller, Walter C ^b   Roche, Patrick C ^a   Nelson, Robin T ^b   Torchia, Anthony J ^b   Kreutter, David K ^b   Butler, Peter C ^a,c  

^a MAYO CLINIC   (United States)

^b PFIZER INC   (United States)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLIN; GLUCOSE; INSULIN;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; INSULIN RELEASE; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; TRANSGENIC MOUSE;

AGING; AMYLOID; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; FEMALE; GLUCAGON; HUMANS; INSULIN; ISLETS OF LANGERHANS; MALE; MICE; MICE, TRANSGENIC; MICROSCOPY, ELECTRON; PROMOTER REGIONS (GENETICS); RATS; SEX CHARACTERISTICS;

EID: 0029901739     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.14.7283     Document Type: Article

References (23)

1. Johnson, K. H., O'Brien, T. D., Betsholtz, C. & Westermark P. (1989) N. Engl. J. Med. 321, 513-518.
2. Johnson, K. H., O'Brien, T. D., Betsholtz, C. & Westermark, P. (1992) Lab. Invest. 66, 522-535.
3. Betsholtz, C., Christmansson, L., Engström, U., Rorsman, F., Svensson, V., Johnson, K. H. & Westermark, P. (1989) FEBS Lett. 251, 261-264.
4. Ohagi, S., Nishi, M., Bell, G. I., Ensinck, J. W. & Steiner, D. F. (1991) Diabetologia 34, 555-558.
5. O'Brien, T. D., Butler, P. C., Kreutter, D. K., Kane, L. A. & Eberhardt, N. L. (1995) Am. J. Pathol. 147, 609-616.
6. Fox, N., Schrementi, J., Nishi, M., Ohagi, S., Chan, S. J., Heisserman, J. A., Westermark, G. T., Leckström, A., Westermark, P. & Steiner, D. F. (1993) FEBS Lett. 323, 40-44.
7. de Koning, E. J. P., Höppener, J. W. M., Verbeek, J. S., Oosterwijk, C., van Hulst, K. L., Baker, C. A., Lips, C. J. M., Morris, J. F. & Clark, A. (1994) Diabetes 43, 640-644.
8. Yagui, K., Yamaguchi, T., Kanatsuka, A., Shimada, F., Huang, C. I., Tokuyama, Y., Ohsawa, H., Yamamura, K.-I., Miyazaki, J.-I., Mikata, A., Yoshida, S. & Makino, H. (1995) Eur. J. Endocrinol. 132, 487-496.
9. Couce, M., Kane, L. A., O'Brien, T. D., Charlesworth, J., Soeller, W., McNeish, J., Kreutter, D., Roche, P. & Butler, P. C. (1996) Diabetes, in press.
10. Butler, P. C., Eberhardt, N. L. & O'Brien, T. D. (1994) in Molecular Biology of Diabetes, Part I, eds. Drazin, B. & LeRoith, D. (Humana, Totowa, NJ), pp. 381-398.
11. Marshall, B. A., Ren, J.-M., Johnson, D. W., Gibbs, E. M., Lillquist, J. S., Soeller, W. C., Holloszy, J. O. & Mueckler, M. (1993) J. Biol. Chem. 268, 18842-18445.
12. Butler, P. C., Chou, J., Carter, W. B., Wang, Y.-N., Bu, B.-H., Chang, D., Chang, J.-K. & Rizza, R. A. (1990) Diabetes 39, 752-756.
13. Couce, M., O'Brien, T. D., Moran, A., Roche, P. C. & Butler, P. C. (1996) J. Clin. Endocrinol. Metab. 81, 1267-1272.
14. Spurr, A. R. (1969) J. Ultrastruc. Res. 71, 173-184.
15. Westermark, P. (1973) Virchows Archiv. A 359, 1-18.
16. May, P. C., Boggs, L. N. & Fuson, K. S. J. (1993) Neurochemistry 61, 2330-2333.
17. Lorenzo, A., Razzaboni, B., Weir, G. C. & Yankner, B. A. (1994) Nature (London) 368, 756-760.
18. O'Brien, T. D., Butler, A. E., Roche, P. C., Johnson, K. H. & Butler, P. C. (1994) Diabetes 43, 329-336.
19. Schubert, D., Behl, C., Lesley, R., Brack, A., Dargusch, R., Sagara, Y. & Kimura, H. (1995) Proc. Natl. Acad. Sci. USA 92, 1989-1993.
20. Davis-Salinas, J. & Van Nostrand, W. E. (1995) J. Biol. Chem. 270, 20887-20890.
21. Efrat, S., Fleischer, N. & Hanahan, D. (1990) Mol. Cell. Biol. 10, 1779-1783.
22. Allison, J., Malcolm, L., Culvenor, J., Bartholomeusz, R. K., Holmberg, K. & Miller, J. F. A. P. (1991) Proc. Natl. Acad. Sci. USA 88, 2070-2074.
23. Gill, A. M., Leiter, E. H., Powell, J. G., Chapman, H. D. & Yen, T. T. (1994) Diabetes 43, 999-1004.