메뉴 건너뛰기




Volumn 6, Issue 3, 2012, Pages 201-207

Quercetin ameliorates hyperglycemia and dyslipidemia and improves antioxidant status in type 2 diabetic db/db mice

Author keywords

Antioxidant; Db db mouse; Dyslipidemia; Hyperglycemia; Quercetin

Indexed keywords

ANIMALIA; MUS;

EID: 84864236699     PISSN: 19761457     EISSN: 20056168     Source Type: Journal    
DOI: 10.4162/nrp.2012.6.3.201     Document Type: Article
Times cited : (212)

References (41)
  • 1
    • 28844503938 scopus 로고    scopus 로고
    • Prevalence, predisposition and prevention of type II diabetes
    • Cheng D. Prevalence, predisposition and prevention of type II diabetes. Nutr Metab (Lond) 2005;2:29.
    • (2005) Nutr Metab (Lond) , vol.2 , pp. 29
    • Cheng, D.1
  • 2
    • 0031752685 scopus 로고    scopus 로고
    • Global burden of diabetes, 1995-2025: Prevalence, numerical estimates, and projections
    • King H, Aubert RE, Herman WH. Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care 1998;21:1414-1431.
    • (1998) Diabetes Care , vol.21 , pp. 1414-1431
    • King, H.1    Aubert, R.E.2    Herman, W.H.3
  • 5
    • 24044513942 scopus 로고    scopus 로고
    • A review on the role of antioxidants in the management of diabetes and its complications
    • Rahimi R, Nikfar S, Larijani B, Abdollahi M. A review on the role of antioxidants in the management of diabetes and its complications. Biomed Pharmacother 2005;59:365-373.
    • (2005) Biomed Pharmacother , vol.59 , pp. 365-373
    • Rahimi, R.1    Nikfar, S.2    Larijani, B.3    Abdollahi, M.4
  • 6
    • 0025037570 scopus 로고
    • Management of dyslipidemia in NIDDM
    • Garg A, Grundy SM. Management of dyslipidemia in NIDDM. Diabetes Care 1990;13:153-169.
    • (1990) Diabetes Care , vol.13 , pp. 153-169
    • Garg, A.1    Grundy, S.M.2
  • 7
    • 0037678289 scopus 로고    scopus 로고
    • Management of dyslipidemia in adults with diabetes
    • American Diabetes Association
    • American Diabetes Association. Management of dyslipidemia in adults with diabetes. Diabetes Care 2003;26 Suppl 1:583-586.
    • (2003) Diabetes Care , vol.26 , Issue.SUPPL. 1 , pp. 583-586
  • 8
    • 78349297565 scopus 로고    scopus 로고
    • Oxidative stress and diabetic complications
    • Giacco F, Brownlee M. Oxidative stress and diabetic complications. Circ Res 2010;107:1058-1070.
    • (2010) Circ Res , vol.107 , pp. 1058-1070
    • Giacco, F.1    Brownlee, M.2
  • 9
    • 34547117120 scopus 로고    scopus 로고
    • Antioxidant and cytotoxic activities of naturally occurring phenolic and related compounds: A comparative study
    • Rao YK, Geethangili M, Fang SH, Tzeng YM. Antioxidant and cytotoxic activities of naturally occurring phenolic and related compounds: a comparative study. Food Chem Toxicol 2007;45: 1770-1776.
    • (2007) Food Chem Toxicol , vol.45 , pp. 1770-1776
    • Rao, Y.K.1    Geethangili, M.2    Fang, S.H.3    Tzeng, Y.M.4
  • 10
    • 43049176634 scopus 로고    scopus 로고
    • Health effects of quercetin: From antioxidant to nutraceutical
    • Boots AW, Haenen GR, Bast A. Health effects of quercetin: from antioxidant to nutraceutical. Eur J Pharmacol 2008;585:325-337.
    • (2008) Eur J Pharmacol , vol.585 , pp. 325-337
    • Boots, A.W.1    Haenen, G.R.2    Bast, A.3
  • 11
    • 1642323567 scopus 로고    scopus 로고
    • Quercetin allievates oxidative stress in streptozotocin-induced diabetic rats
    • Mahesh T, Menon VP. Quercetin allievates oxidative stress in streptozotocin-induced diabetic rats. Phytother Res 2004;18: 123-127.
    • (2004) Phytother Res , vol.18 , pp. 123-127
    • Mahesh, T.1    Menon, V.P.2
  • 12
    • 26444581298 scopus 로고    scopus 로고
    • Quercetin decreases oxidative stress, NF-kappaB activation, and iNOS overexpression in liver of streptozo-tocin-induced diabetic rats
    • Dias AS, Porawski M, Alonso M, Marroni N, Collado PS, González-Gallego J. Quercetin decreases oxidative stress, NF-kappaB activation, and iNOS overexpression in liver of streptozo-tocin-induced diabetic rats. J Nutr 2005;135:2299-2304.
    • (2005) J Nutr , vol.135 , pp. 2299-2304
    • Dias, A.S.1    Porawski, M.2    Alonso, M.3    Marroni, N.4    Collado, P.S.5    González-Gallego, J.6
  • 13
    • 79953317030 scopus 로고    scopus 로고
    • Chronic dietary intake of quercetin alleviates hepatic fat accumulation associated with consumption of a Western-style diet in C57/BL6J mice
    • Kobori M, Masumoto S, Akimoto Y, Oike H. Chronic dietary intake of quercetin alleviates hepatic fat accumulation associated with consumption of a Western-style diet in C57/BL6J mice. Mol Nutr Food Res 2011;55:530-540.
    • (2011) Mol Nutr Food Res , vol.55 , pp. 530-540
    • Kobori, M.1    Masumoto, S.2    Akimoto, Y.3    Oike, H.4
  • 14
  • 15
    • 77950917531 scopus 로고    scopus 로고
    • A comparative study of flavonoid analogues on streptozotocin-nicotinamide induced diabetic rats: Quercetin as a potential antidiabetic agent acting via 11beta-hydroxysteroid dehydrogenase type 1 inhibition
    • Torres-Piedra M, Ortiz-Andrade R, Villalobos-Molina R, Singh N, Medina-Franco JL, Webster SP, Binnie M, Navarrete-Vázquez G, Estrada-Soto S. A comparative study of flavonoid analogues on streptozotocin-nicotinamide induced diabetic rats: quercetin as a potential antidiabetic agent acting via 11beta-hydroxysteroid dehydrogenase type 1 inhibition. Eur J Med Chem 2010;45:2606-2612.
    • (2010) Eur J Med Chem , vol.45 , pp. 2606-2612
    • Torres-Piedra, M.1    Ortiz-Andrade, R.2    Villalobos-Molina, R.3    Singh, N.4    Medina-Franco, J.L.5    Webster, S.P.6    Binnie, M.7    Navarrete-Vázquez, G.8    Estrada-Soto, S.9
  • 17
    • 79956271261 scopus 로고    scopus 로고
    • Comparison of antioxidant potential and rat intestinal α-glucosi-dases inhibitory activities of quercetin, rutin, and isoquercetin
    • Jo SH, Ka EH, Lee HS, Apostolidis E, Jang HD, Kwon YI. Comparison of antioxidant potential and rat intestinal α-glucosi-dases inhibitory activities of quercetin, rutin, and isoquercetin. Int J Applied Res Nat Prod 2009;2:52-60.
    • (2009) Int J Applied Res Nat Prod , vol.2 , pp. 52-60
    • Jo, S.H.1    Ka, E.H.2    Lee, H.S.3    Apostolidis, E.4    Jang, H.D.5    Kwon, Y.I.6
  • 18
    • 79956273349 scopus 로고    scopus 로고
    • Quercetin attenuates fasting and postprandial hyperglycemia in animal models of diabetes mellitus
    • Kim JH, Kang MJ, Choi HN, Jeong SM, Lee YM, Kim JI. Quercetin attenuates fasting and postprandial hyperglycemia in animal models of diabetes mellitus. Nutr Res Pract 2011;5: 107-111.
    • (2011) Nutr Res Pract , vol.5 , pp. 107-111
    • Kim, J.H.1    Kang, M.J.2    Choi, H.N.3    Jeong, S.M.4    Lee, Y.M.5    Kim, J.I.6
  • 19
    • 17444369379 scopus 로고    scopus 로고
    • Quercetin alleviates activities of intestinal and renal disaccharidases in streptozotocin-induced diabetic rats
    • Ramachandra R, Shetty AK, Salimath PV. Quercetin alleviates activities of intestinal and renal disaccharidases in streptozotocin-induced diabetic rats. Mol Nutr Food Res 2005;49:355-360.
    • (2005) Mol Nutr Food Res , vol.49 , pp. 355-360
    • Ramachandra, R.1    Shetty, A.K.2    Salimath, P.V.3
  • 20
    • 2942620341 scopus 로고    scopus 로고
    • Antidiabetic influence of quercetin in streptozotocin-induced diabetic rats
    • Shetty AK, Rashmi R, Rajan MGR, Sambaiah K, Salimath PV. Antidiabetic influence of quercetin in streptozotocin-induced diabetic rats. Nutr Res 2004;24:373-381.
    • (2004) Nutr Res , vol.24 , pp. 373-381
    • Shetty, A.K.1    Rashmi, R.2    Rajan, M.G.R.3    Sambaiah, K.4    Salimath, P.V.5
  • 21
    • 0027487229 scopus 로고
    • AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet
    • Reeves PG, Nielsen FH, Fahey GC Jr. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 1993;123:1939-1951.
    • (1993) J Nutr , vol.123 , pp. 1939-1951
    • Reeves, P.G.1    Nielsen, F.H.2    Fahey J.R., G.C.3
  • 22
    • 0030994947 scopus 로고    scopus 로고
    • The homeostasis model in the San Antonio Heart Study
    • Haffner SM, Miettinen H, Stern MP. The homeostasis model in the San Antonio Heart Study. Diabetes Care 1997;20:1087-1092.
    • (1997) Diabetes Care , vol.20 , pp. 1087-1092
    • Haffner, S.M.1    Miettinen, H.2    Stern, M.P.3
  • 23
    • 0018384650 scopus 로고
    • Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction
    • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:351-358.
    • (1979) Anal Biochem , vol.95 , pp. 351-358
    • Ohkawa, H.1    Ohishi, N.2    Yagi, K.3
  • 24
    • 0000024078 scopus 로고
    • Catalase
    • In: Bergmeyer HU, editor, New York: Academic Press
    • Aebi H. Catalase. In: Bergmeyer HU, editor. Methods of Enzymatic Analysis. New York: Academic Press; 1974. p.673-683.
    • (1974) Methods of Enzymatic Analysis , pp. 673-683
    • Aebi, H.1
  • 25
    • 0014108436 scopus 로고
    • Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase
    • Paglia DE, Valentine WN. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J Lab Clin Med 1967;70:158-169.
    • (1967) J Lab Clin Med , vol.70 , pp. 158-169
    • Paglia, D.E.1    Valentine, W.N.2
  • 26
    • 0016272750 scopus 로고
    • Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase
    • Marklund S, Marklund G. Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974;47:469-474.
    • (1974) Eur J Biochem , vol.47 , pp. 469-474
    • Marklund, S.1    Marklund, G.2
  • 27
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 28
    • 0033157223 scopus 로고    scopus 로고
    • Effect of acarbose on additional insulin therapy in type 2 diabetic patients with late failure of sulphonylurea therapy
    • Standl E, Baumgartl HJ, Füchtenbusch M, Stemplinger J. Effect of acarbose on additional insulin therapy in type 2 diabetic patients with late failure of sulphonylurea therapy. Diabetes Obes Metab 1999;1:215-220.
    • (1999) Diabetes Obes Metab , vol.1 , pp. 215-220
    • Standl, E.1    Baumgartl, H.J.2    Füchtenbusch, M.3    Stemplinger, J.4
  • 29
    • 38349006256 scopus 로고    scopus 로고
    • Current approaches for assessing insulin sensitivity and resistance in vivo: Advantages, limitations, and appropriate usage
    • Muniyappa R, Lee S, Chen H, Quon MJ. Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. Am J Physiol Endocrinol Metab 2008;294:E15-E26.
    • (2008) Am J Physiol Endocrinol Metab , vol.294
    • Muniyappa, R.1    Lee, S.2    Chen, H.3    Quon, M.J.4
  • 30
    • 44949237971 scopus 로고    scopus 로고
    • Adiponectin and its association with insulin resistance and type 2 diabetes
    • Sheng T, Yang K. Adiponectin and its association with insulin resistance and type 2 diabetes. J Genet Genomics 2008;35:321-326.
    • (2008) J Genet Genomics , vol.35 , pp. 321-326
    • Sheng, T.1    Yang, K.2
  • 31
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • The Diabetes Control and Complications Trial Research Group
    • The Diabetes Control and Complications Trial Research Group. The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N Engl J Med 1993;329:977-986.
    • (1993) N Engl J Med , vol.329 , pp. 977-986
  • 32
    • 68349147819 scopus 로고    scopus 로고
    • Quercetin inhibits fatty acid and triacylglycerol synthesis in rat-liver cells
    • Gnoni GV, Paglialonga G, Siculella L. Quercetin inhibits fatty acid and triacylglycerol synthesis in rat-liver cells. Eur J Clin Invest 2009;39:761-768.
    • (2009) Eur J Clin Invest , vol.39 , pp. 761-768
    • Gnoni, G.V.1    Paglialonga, G.2    Siculella, L.3
  • 34
    • 0031975337 scopus 로고    scopus 로고
    • Management of dyslipidemia in adults with diabetes
    • Haffner SM. Management of dyslipidemia in adults with diabetes. Diabetes Care 1998;21:160-178.
    • (1998) Diabetes Care , vol.21 , pp. 160-178
    • Haffner, S.M.1
  • 35
    • 0027406191 scopus 로고
    • Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial
    • Stamler J, Vaccaro O, Neaton JD, Wentworth D. Diabetes, other risk factors, and 12-yr cardiovascular mortality for men screened in the Multiple Risk Factor Intervention Trial. Diabetes Care 1993;16:434-444.
    • (1993) Diabetes Care , vol.16 , pp. 434-444
    • Stamler, J.1    Vaccaro, O.2    Neaton, J.D.3    Wentworth, D.4
  • 36
    • 0035176943 scopus 로고    scopus 로고
    • The oxidative modification hypothesis of atherosclerosis: Does it hold for humans?
    • Witztum JL, Steinberg D. The oxidative modification hypothesis of atherosclerosis: does it hold for humans? Trends Cardiovasc Med 2001;11:93-102.
    • (2001) Trends Cardiovasc Med , vol.11 , pp. 93-102
    • Witztum, J.L.1    Steinberg, D.2
  • 37
    • 33645509709 scopus 로고    scopus 로고
    • Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation
    • Du X, Edelstein D, Obici S, Higham N, Zou MH, Brownlee M. Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation. J Clin Invest 2006;116:1071-1080.
    • (2006) J Clin Invest , vol.116 , pp. 1071-1080
    • Du, X.1    Edelstein, D.2    Obici, S.3    Higham, N.4    Zou, M.H.5    Brownlee, M.6
  • 38
    • 0028318752 scopus 로고
    • The correlation between active oxygens scavenging and antioxidative effects of flavonoids
    • Hanasaki Y, Ogawa S, Fukui S. The correlation between active oxygens scavenging and antioxidative effects of flavonoids. Free Radic Biol Med 1994;16:845-850.
    • (1994) Free Radic Biol Med , vol.16 , pp. 845-850
    • Hanasaki, Y.1    Ogawa, S.2    Fukui, S.3
  • 39
    • 3042574709 scopus 로고    scopus 로고
    • Potential toxicity of flavonoids and other dietary phenolics: Significance for their chemopreventive and anticancer properties
    • Galati G, O'Brien PJ. Potential toxicity of flavonoids and other dietary phenolics: significance for their chemopreventive and anticancer properties. Free Radic Biol Med 2004;37:287-303.
    • (2004) Free Radic Biol Med , vol.37 , pp. 287-303
    • Galati, G.1    O'Brien, P.J.2
  • 40
    • 0026047662 scopus 로고
    • The aging process: Major risk factor for disease and death
    • Harman D. The aging process: major risk factor for disease and death. Proc Natl Acad Sci U S A 1991;88:5360-5363.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 5360-5363
    • Harman, D.1
  • 41
    • 0036086130 scopus 로고    scopus 로고
    • Free radicals in the physiological control of cell function
    • Dröge W. Free radicals in the physiological control of cell function. Physiol Rev 2002;82:47-95.
    • (2002) Physiol Rev , vol.82 , pp. 47-95
    • Dröge, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.