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Volumn 414, Issue 6865, 2001, Pages 813-820

Biochemistry and molecular cell biology of diabetic complications

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; DISEASES; DRUG PRODUCTS; GLUCOSE; RISKS;

EID: 0035856980     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/414813a     Document Type: Review
Times cited : (7531)

References (100)
  • 1
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • (1993) N. Engl. J. Med. , vol.329 , pp. 977-986
  • 2
    • 0032511583 scopus 로고    scopus 로고
    • Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)
    • (1998) Lancet , vol.352 , pp. 837-853
  • 4
    • 0033917880 scopus 로고    scopus 로고
    • Delayed catabolism of apoB-48 lipoproteins due to decreased heparan sulfate proteoglycan production in diabetic mice
    • (2000) J. Clin. Invest. , vol.105 , pp. 1807-1818
    • Ebara, T.1
  • 8
    • 0032719024 scopus 로고    scopus 로고
    • Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats
    • (1999) J. Clin. Invest. , vol.104 , pp. 447-457
    • Jiang, Z.Y.1
  • 9
    • 0032485927 scopus 로고    scopus 로고
    • Acute hyperglycemia attenuates endothelium-dependent vasodilation in humans in vivo
    • (1998) Circulation , vol.97 , pp. 1695-1701
    • Williams, S.B.1
  • 10
    • 0034710891 scopus 로고    scopus 로고
    • Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 12222-12226
    • Du, X.L.1
  • 11
    • 0033646935 scopus 로고    scopus 로고
    • Postchallenge plasma glucose and glycemic spikes are more strongly associated with atherosclerosis than fasting glucose or HbAlc levels
    • (2000) Diabetes Care , vol.12 , pp. 1830-1834
    • Temelkova-Kurktschiev, T.S.1
  • 13
    • 0029087910 scopus 로고
    • Identification of the mechanism for the inhibition of Na,K-adenosine triphosphatase by hyperglycemia involving act Nation of protein kinase C and cytosolic phospholipase A2
    • (1995) J. Clin. Invest. , vol.96 , pp. 733-740
    • Xia, P.1    Kramer, R.M.2    King, G.L.3
  • 15
    • 0035136240 scopus 로고    scopus 로고
    • Diabetic endothelial dysfunction: The role of poly (ADP-ribose) polymerase activation
    • (2001) Nature Med. , vol.7 , pp. 108-113
    • Garcia Soriano, F.1
  • 16
  • 18
    • 0025073693 scopus 로고
    • A randomized trial of sorbinil, an aldose reductase inhibitor, in diabetic retinopathy
    • (1990) Arch. Ophthalmol. , vol.108 , pp. 1234-1244
  • 20
    • 0031019612 scopus 로고    scopus 로고
    • Advanced glycation end products (AGEs) co-localize with AGE receptors in the retinal vasculature of diabetic and of AGE-infused rats
    • (1997) Am. J. Pathol. , vol.150 , pp. 523-528
    • Stitt, A.W.1
  • 21
    • 0031453830 scopus 로고    scopus 로고
    • Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy
    • (1997) J. Clin. Invest. , vol.100 , pp. 2995-2999
    • Horie, K.1
  • 23
    • 0028951461 scopus 로고
    • Mechanism of autoxidative glycosylation: Identification of glyoxal and arabinose as intermediates in the autoxidative modification of proteins by glucose
    • (1995) Biochemistry , vol.34 , pp. 3702-3709
    • Wells-Knecht, K.J.1
  • 24
    • 0025298551 scopus 로고
    • The glyoxalase system: New developments towards functional characterization of a metabolic pathway fundamental to biological life
    • (1990) Biochem. J. , vol.269 , pp. 1-11
    • Thornalley, P.J.1
  • 25
    • 0031932312 scopus 로고    scopus 로고
    • Overexpression of aldehyde reductase protects PC12 cells from the cytotoxicity of methylglyoxal or 3-deoxyglucosone
    • (1998) J. Biochem. , vol.123 , pp. 353-357
    • Suzuki, K.1
  • 27
    • 0030906581 scopus 로고    scopus 로고
    • Progression of nephropathy in spontaneous diabetic rats is prevented by OPB. 9195, a novel inhibitor of advanced glycation
    • (1997) Diabetes , vol.46 , pp. 895-899
    • Nakamura, S.1
  • 30
    • 0032032578 scopus 로고    scopus 로고
    • Overexpression of glyoxalase-I in bovine endothelial cells inhibits intracellular advanced glycation end product formation and prevents hyperglycemia-induced increases in macromolecular endocytosis
    • (1998) J. Clin. Invest. , vol.101 , pp. 1142-1147
    • Shinohara, M.1
  • 31
    • 15144358851 scopus 로고    scopus 로고
    • Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis
    • (1997) Science , vol.277 , pp. 55-60
    • Maisonpierre, P.C.1
  • 33
    • 0027291535 scopus 로고
    • Aminoguanidine treatment increases elasticity and decreases fluid filtration of large arteries from diabetic rats
    • (1993) J. Clin. Invest. , vol.92 , pp. 1407-1411
    • Huijberts, M.S.P.1
  • 34
    • 0023932850 scopus 로고
    • The effect of nonenzymatic glucosylation the binding of the main noncollagenous NCl domain to type IV collagen
    • (1990) J. Biol. Chem. , vol.263 , pp. 4302-4308
    • Tsilbary, E.C.1
  • 35
    • 0025369394 scopus 로고
    • Laminin alterations after in vitro nonenzymatic glucosylation
    • (1988) Diabetes , vol.39 , pp. 807-814
    • Charonis, A.S.1
  • 38
    • 0001263746 scopus 로고    scopus 로고
    • Molecular identity and cellular distribution of advanced glycation end product receptors: Relationship of p60 to OST-48 and p90 to 80K-H membrane proteins
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11047-11052
    • Li, Y.M.1
  • 39
    • 0031050251 scopus 로고    scopus 로고
    • Advanced glycation end products are eliminated by scavenger-receptor-mediated endocytosis in hepatic sinusoidal kupffer and endothelial cells
    • (1997) Biochem J. , vol.322 , pp. 567-573
    • Smedsrod, B.1
  • 40
    • 0029366113 scopus 로고
    • Identification of galectin-3 as a high-affinity, binding protein for advanced glycation end products (AGE): A new member of the AGE-receptor
    • (1995) Mol. Med. , vol.1 , pp. 634-646
    • Vlassara, H.1
  • 41
    • 0026659883 scopus 로고
    • Cloning and expression of RAGE: A cell surface-receptor for advanced glycosylation end products of proteins
    • (1992) J. Biol. Chem. , vol.267 , pp. 14998-15004
    • Neeper, M.1
  • 42
    • 0023940640 scopus 로고
    • Cachectin/TNF and IL-1 induced by glucose-modified proteins: Role in normal tissue remodeling
    • (1988) Science , vol.240 , pp. 1546-1548
    • Vlassara, H.1
  • 44
    • 0030273623 scopus 로고    scopus 로고
    • Synthesis and secretion of macrophage colony stimulating factor by mature human monocytes and human monocytic THP-1 cells induced by human serum albumin derivatives modified with methylglyoxal and glucose-derived advanced glycation end products
    • (1996) Immunol. Lett. , vol.53 , pp. 7-13
    • Abordo, E.A.1    Westwood, M.E.2    Thornalley, P.J.3
  • 45
    • 0026042328 scopus 로고
    • Human and rat mesangial cell receptors for glucose-modified proteins: Potential role in kidney tissue remodelling and diabetic nephropathy
    • (1991) J. Exp. Med. , vol.174 , pp. 931-939
    • Skolnik, E.Y.1
  • 46
    • 0026603130 scopus 로고
    • Receptor specific increase in extracellular matrix productions in mouse mesangial cells by advanced glycosylation end products is mediated via platelet derived growth factor
    • (1992) Proc. Natl Acad. Sci. , vol.89 , pp. 2873-2877
    • Doi, T.1
  • 47
    • 0029088742 scopus 로고
    • Advanced glycation end products interacting with their endothelial receptor induce expression of vascular cell adhesion molecule-1 (VCAM-1) in cultured human endothelial cells and in mice: A potential mechanism for the accelerated vasculopathy of diabetes
    • (1995) J. Clin. Invest. , vol.96 , pp. 1395-1403
    • Schmidt, A.M.1
  • 48
    • 0032520871 scopus 로고    scopus 로고
    • Advanced glycation endproducts increase retinal vascular endothelial growth factor expression
    • (1998) J. Clin. Invest. , vol.101 , pp. 1219-1224
    • Lu, M.1
  • 49
    • 0031717894 scopus 로고    scopus 로고
    • Suppression of accelerated diabetic atherosclerosis by the soluble receptor for advanced glycation endproducts
    • (1998) Nature Med. , vol.4 , pp. 1025-1031
    • Park, L.1
  • 50
    • 0028304625 scopus 로고
    • Enhanced cellular oxidant stress by the interaction of advanced glycation end products with their receptors/binding proteins
    • (1994) J. Biol. Chem. , vol.269 , pp. 9889-9897
    • Yan, S.D.1
  • 51
    • 0030859290 scopus 로고    scopus 로고
    • Activation of the receptor for advanced glycation end products triggers a p21(ras)-dependent mitogen-activated protein kinase pathway regulated by oxidant stress
    • (1997) J. Biol. Chem. , vol.272 , pp. 17810-17814
    • Lander, H.M.1
  • 52
    • 0031773362 scopus 로고    scopus 로고
    • Advanced glycation endproducts inhibit prostacyclin production and induce plasminogen activator inhibitor-1 in human microvascular endothelial cells
    • (1998) Diabetologia , vol.41 , pp. 1435-1441
    • Yamagishi, S.1
  • 54
    • 0031860340 scopus 로고    scopus 로고
    • Protein kinase C activation and the development of diabetic complications
    • (1998) Diabetes , vol.47 , pp. 859-866
    • Koya, D.1    King, G.L.2
  • 55
    • 0027981889 scopus 로고
    • Characterization of the mechanism for the chronic activation of diacylglycerol-protein kinase C pathway in diabetes and hypergalactosemia
    • (1994) Diabetes , vol.43 , pp. 1122-1129
    • Xia, P.1
  • 56
    • 0030760729 scopus 로고    scopus 로고
    • Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats
    • (1997) J. Clin. Invest. , vol.100 , pp. 115-126
    • Koya, D.1
  • 58
  • 59
    • 13344293711 scopus 로고    scopus 로고
    • Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor
    • (1996) Science , vol.272 , pp. 728-731
    • Ishii, H.1
  • 60
    • 0028039015 scopus 로고
    • Impaired nitric oxide-dependent cyclic guanosine monophosphate generation in glomeruli from diabetic rats. Evidence for protein kinase C-mediated suppression of the cholinergic response
    • (1994) J. Clin. Invest. , vol.93 , pp. 311-320
    • Craven, P.A.1    Studer, R.K.2    DeRubertis, F.R.3
  • 62
    • 0034651949 scopus 로고    scopus 로고
    • Regulation of endothelial constitutive nitric oxide synthase gene expression in endothelial cells and in vivo a specific vascular action of insulin
    • (2000) Circulation , vol.101 , pp. 676-681
    • Kuboki, K.1
  • 64
    • 0030743466 scopus 로고    scopus 로고
    • High glucose concentrations increase endothelial cell permeability via activation of protein kinase C alpha
    • (1997) Circ. Res. , vol.81 , pp. 363-371
    • Hempel, A.1
  • 65
    • 0030863502 scopus 로고    scopus 로고
    • Glucose-induced protein kinase C activation regulates vascular permeability factor mRNA expression and peptide production by human vascular smooth muscle cells in vitro
    • (1997) Diabetes , vol.46 , pp. 1497-1503
    • Williams, B.1    Gallacher, B.2    Patel, H.3    Orme, C.4
  • 67
    • 0030760729 scopus 로고    scopus 로고
    • Characterization of protein kinase C beta isoform activation on the gene expression of transforming growth factor-beta, extracellular matrix components, and prostanoids in the glomeruli of diabetic rats
    • (1997) J. Clin. Invest. , vol.100 , pp. 115-126
    • Koya, D.1
  • 70
    • 0029692743 scopus 로고    scopus 로고
    • Role of protein kinase C in glucose- and angiotensin II-induced plasminogen activator inhibitor expression
    • (1996) Contrib. Nephrol. , vol.118 , pp. 180-187
    • Feener, E.P.1
  • 73
    • 0034053336 scopus 로고    scopus 로고
    • Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes
    • (2000) FASEB J. , vol.14 , pp. 439-447
    • Koya, D.1
  • 75
    • 0025855139 scopus 로고
    • Discovery of a metabolic pathway mediating glucoseinduced desensitization of the glucose transport system. Role of hexosamine biosynthesis in the induction of insulin resistance
    • (1991) J. Biol. Chem. , vol.266 , pp. 4706-4712
    • Marshall, S.1    Bacote, V.2    Traxinger, R.R.3
  • 77
    • 0032478827 scopus 로고    scopus 로고
    • Sp1 sites mediate activation of the plasminogen activator inhibitor- 1 promoter by glucose in vascular smooth muscle cells
    • (1998) J. Biol. Chem. , vol.273 , pp. 8225-8231
    • Chen, Y.Q.1
  • 80
    • 0032488979 scopus 로고    scopus 로고
    • Modulation of O-linked N-acetylglucosamine levels on nuclear and cytoplasmic proteins in vivo using the peptide O-GlcNAc-beta-Nacetylglucosaminidase inhibitor O-(2-acetamido-2-deoxy-D-glucopyranosylidene)amino-N-phenylcarbamate
    • (1998) J. Biol. Chem. , vol.273 , pp. 3611-3617
    • Haltiwanger, R.S.1    Grove, K.2    Philipsberg, G.A.3
  • 82
    • 85047683473 scopus 로고    scopus 로고
    • Hyperglycemia inhibits endothelial nitric oxide synthase activity by posttranslational modification at the AKT site
    • in the press
    • J. Clin. Invest.
    • Du, X.D.1
  • 84
    • 0034643340 scopus 로고    scopus 로고
    • Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
    • (2000) Nature , vol.404 , pp. 787-790
    • Nishikawa, T.1
  • 92
    • 0034628425 scopus 로고    scopus 로고
    • Retinopathy and nephropathy in patients with type 1 diabetes four years after a trial of intensive therapy
    • (2000) N. Engl. J. Med. , vol.342 , pp. 381-389
  • 94
    • 0030725948 scopus 로고    scopus 로고
    • Clustering of long-term complications in families with diabetes in the diabetes control and complications trial
    • (1997) Diabetes , vol.46 , pp. 1829-1839
  • 95
    • 0035078831 scopus 로고    scopus 로고
    • Familial aggregation of coronary artery calcium in families with type 2 diabetes
    • (2001) Diabetes , vol.50 , pp. 861-866
    • Wagenknecht, L.E.1
  • 96
    • 0035434119 scopus 로고    scopus 로고
    • Abnormalities of retinal metabolism in diabetes and experimental galactosemia. VII. Effect of long-term administration of antioxidants on the development of retinopathy
    • (2001) Diabetes , vol.50 , pp. 1938-1942
    • Kowluru, R.A.1    Tang, J.2    Kern, T.S.3
  • 97
    • 0030034465 scopus 로고    scopus 로고
    • Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus
    • (1996) J. Clin. Invest. , vol.97 , pp. 22-28
    • Ting, H.H.1
  • 98
    • 0001670692 scopus 로고    scopus 로고
    • Heart Outcomes Prevention Evaluation Study Investigators. Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: Results of the HOPE study and MICROHOPE substudy
    • (2000) Lancet , vol.355 , pp. 253-259
  • 99
    • 0033536644 scopus 로고    scopus 로고
    • A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats
    • (1999) Science , vol.286 , pp. 304-306
    • Salvemini, D.1


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