Impaired glucose tolerance and insulin resistance are associated with increased adipose 11 β-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5α-reductase activity

Diabetes

Volumn 57, Issue 10, 2008, Pages 2652-2660

  Tomlinson, Jeremy W ^a   Finney, Joanne ^b   Gay, Christopher ^a   Hughes, Beverly A ^a   Hughes, Susan V ^a   Stewart, Paul M ^a  

^a University of Birmingham   (United Kingdom)

^b UNIVERSITY HOSPITALS BIRMINGHAM NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 1; CORTISONE; HYDROCORTISONE; INSULIN; STEROID; STEROID 5ALPHA REDUCTASE; CHOLESTENONE 5ALPHA REDUCTASE; GLUCOCORTICOID;

ABDOMINAL FAT ASPIRATION BIOPSY; ADULT; ARTICLE; BODY COMPOSITION; BODY MASS; CLINICAL ASSESSMENT; DISEASE ASSOCIATION; DUAL ENERGY X RAY ABSORPTIOMETRY; ENZYME METABOLISM; FEMALE; GAS CHROMATOGRAPHY; HOMEOSTASIS; HUMAN; HYDROCORTISONE BLOOD LEVEL; IMPAIRED GLUCOSE TOLERANCE; INSULIN BLOOD LEVEL; INSULIN RELEASE; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PRIORITY JOURNAL; SEX DIFFERENCE; STEROID URINE LEVEL; URINALYSIS; ADIPOSE TISSUE; ENZYMOLOGY; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; LIVER; MASS FRAGMENTOGRAPHY; METABOLISM; MIDDLE AGED; PATHOPHYSIOLOGY; PHOTON ABSORPTIOMETRY; PHYSIOLOGY; REGRESSION ANALYSIS; URINE;

11-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1; ABSORPTIOMETRY, PHOTON; ADIPOSE TISSUE; ADULT; BODY MASS INDEX; CHOLESTENONE 5 ALPHA-REDUCTASE; CORTISONE; FEMALE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLUCOCORTICOIDS; GLUCOSE INTOLERANCE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN RESISTANCE; LIVER; MALE; MIDDLE AGED; OBESITY; REGRESSION ANALYSIS; SEX FACTORS;

EID: 58149330675     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db08-0495     Document Type: Article

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