-
1
-
-
21444448910
-
Coffee consumption and risk of type 2 diabetes: a systematic review
-
van Dam R.M., and Hu F.B. Coffee consumption and risk of type 2 diabetes: a systematic review. JAMA 294 (2005) 97-104
-
(2005)
JAMA
, vol.294
, pp. 97-104
-
-
van Dam, R.M.1
Hu, F.B.2
-
2
-
-
33645981256
-
Coffee and type 2 diabetes: from beans to beta-cells
-
van Dam R.M. Coffee and type 2 diabetes: from beans to beta-cells. Nutr. Metab. Cardiovasc. Dis. 16 (2006) 69-77
-
(2006)
Nutr. Metab. Cardiovasc. Dis.
, vol.16
, pp. 69-77
-
-
van Dam, R.M.1
-
3
-
-
4444269459
-
Role of stress in the pathogenesis of the metabolic syndrome
-
Rosmond R. Role of stress in the pathogenesis of the metabolic syndrome. Psychoneuroendocrinology 30 (2005) 1-10
-
(2005)
Psychoneuroendocrinology
, vol.30
, pp. 1-10
-
-
Rosmond, R.1
-
4
-
-
12444257790
-
Role of glucocorticoids in the physiopathology of excessive fat deposition and insulin resistance
-
Asensio C., Muzzin P., and Rohner-Jeanrenaud F. Role of glucocorticoids in the physiopathology of excessive fat deposition and insulin resistance. Int. J. Obes. Relat. Metab. Disord. 28 Suppl. 4 (2004) S45-S52
-
(2004)
Int. J. Obes. Relat. Metab. Disord.
, vol.28
, Issue.SUPPL. 4
-
-
Asensio, C.1
Muzzin, P.2
Rohner-Jeanrenaud, F.3
-
5
-
-
23644453298
-
11Beta-hydroxysteroid dehydrogenase type 1 in human disease: a novel therapeutic target
-
Tomlinson J.W. 11Beta-hydroxysteroid dehydrogenase type 1 in human disease: a novel therapeutic target. Minerva Endocrinol. 30 (2005) 37-46
-
(2005)
Minerva Endocrinol.
, vol.30
, pp. 37-46
-
-
Tomlinson, J.W.1
-
7
-
-
33645784827
-
Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 for the treatment of metabolic syndrome
-
Wang M. Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1 for the treatment of metabolic syndrome. Curr. Opin. Invest. Drugs 7 (2006) 319-323
-
(2006)
Curr. Opin. Invest. Drugs
, vol.7
, pp. 319-323
-
-
Wang, M.1
-
8
-
-
0031283178
-
11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress
-
Kotelevtsev Y., Holmes M.C., Burchell A., Houston P.M., Schmoll D., Jamieson P., Best R., Brown R., Edwards C.R., Seckl J.R., and Mullins J.J. 11beta-hydroxysteroid dehydrogenase type 1 knockout mice show attenuated glucocorticoid-inducible responses and resist hyperglycemia on obesity or stress. Proc. Natl. Acad. Sci. USA 94 (1997) 14924-14929
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 14924-14929
-
-
Kotelevtsev, Y.1
Holmes, M.C.2
Burchell, A.3
Houston, P.M.4
Schmoll, D.5
Jamieson, P.6
Best, R.7
Brown, R.8
Edwards, C.R.9
Seckl, J.R.10
Mullins, J.J.11
-
9
-
-
0035798621
-
Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11beta-hydroxysteroid dehydrogenase type 1 null mice
-
Morton N.M., Holmes M.C., Fievet C., Staels B., Tailleux A., Mullins J.J., and Seckl J.R. Improved lipid and lipoprotein profile, hepatic insulin sensitivity, and glucose tolerance in 11beta-hydroxysteroid dehydrogenase type 1 null mice. J. Biol. Chem. 276 (2001) 41293-41300
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 41293-41300
-
-
Morton, N.M.1
Holmes, M.C.2
Fievet, C.3
Staels, B.4
Tailleux, A.5
Mullins, J.J.6
Seckl, J.R.7
-
10
-
-
0035824440
-
A transgenic model of visceral obesity and the metabolic syndrome
-
Masuzaki H., Paterson J., Shinyama H., Morton N.M., Mullins J.J., Seckl J.R., and Flier J.S. A transgenic model of visceral obesity and the metabolic syndrome. Science 294 (2001) 2166-2170
-
(2001)
Science
, vol.294
, pp. 2166-2170
-
-
Masuzaki, H.1
Paterson, J.2
Shinyama, H.3
Morton, N.M.4
Mullins, J.J.5
Seckl, J.R.6
Flier, J.S.7
-
11
-
-
85047693986
-
Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice
-
Masuzaki H., Yamamoto H., Kenyon C.J., Elmquist J.K., Morton N.M., Paterson J.M., Shinyama H., Sharp M.G., Fleming S., Mullins J.J., Seckl J.R., and Flier J.S. Transgenic amplification of glucocorticoid action in adipose tissue causes high blood pressure in mice. J. Clin. Invest. 112 (2003) 83-90
-
(2003)
J. Clin. Invest.
, vol.112
, pp. 83-90
-
-
Masuzaki, H.1
Yamamoto, H.2
Kenyon, C.J.3
Elmquist, J.K.4
Morton, N.M.5
Paterson, J.M.6
Shinyama, H.7
Sharp, M.G.8
Fleming, S.9
Mullins, J.J.10
Seckl, J.R.11
Flier, J.S.12
-
12
-
-
2342510149
-
Metabolic syndrome without obesity: hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice
-
Paterson J.M., Morton N.M., Fievet C., Kenyon C.J., Holmes M.C., Staels B., Seckl J.R., and Mullins J.J. Metabolic syndrome without obesity: hepatic overexpression of 11beta-hydroxysteroid dehydrogenase type 1 in transgenic mice. Proc. Natl. Acad. Sci. USA 101 (2004) 7088-7093
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 7088-7093
-
-
Paterson, J.M.1
Morton, N.M.2
Fievet, C.3
Kenyon, C.J.4
Holmes, M.C.5
Staels, B.6
Seckl, J.R.7
Mullins, J.J.8
-
13
-
-
0036432995
-
Selective inhibition of 11beta-hydroxysteroid dehydrogenase type 1 decreases blood glucose concentrations in hyperglycaemic mice
-
Alberts P., Engblom L., Edling N., Forsgren M., Klingstrom G., Larsson C., Ronquist-Nii Y., Ohman B., and Abrahmsen L. Selective inhibition of 11beta-hydroxysteroid dehydrogenase type 1 decreases blood glucose concentrations in hyperglycaemic mice. Diabetologia 45 (2002) 1528-1532
-
(2002)
Diabetologia
, vol.45
, pp. 1528-1532
-
-
Alberts, P.1
Engblom, L.2
Edling, N.3
Forsgren, M.4
Klingstrom, G.5
Larsson, C.6
Ronquist-Nii, Y.7
Ohman, B.8
Abrahmsen, L.9
-
14
-
-
0242468543
-
Selective inhibition of 11 beta-hydroxysteroid dehydrogenase type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains
-
Alberts P., Nilsson C., Selen G., Engblom L.O., Edling N.H., Norling S., Klingstrom G., Larsson C., Forsgren M., Ashkzari M., Nilsson C.E., Fiedler M., Bergqvist E., Ohman B., Bjorkstrand E., and Abrahmsen L.B. Selective inhibition of 11 beta-hydroxysteroid dehydrogenase type 1 improves hepatic insulin sensitivity in hyperglycemic mice strains. Endocrinology 144 (2003) 4755-4762
-
(2003)
Endocrinology
, vol.144
, pp. 4755-4762
-
-
Alberts, P.1
Nilsson, C.2
Selen, G.3
Engblom, L.O.4
Edling, N.H.5
Norling, S.6
Klingstrom, G.7
Larsson, C.8
Forsgren, M.9
Ashkzari, M.10
Nilsson, C.E.11
Fiedler, M.12
Bergqvist, E.13
Ohman, B.14
Bjorkstrand, E.15
Abrahmsen, L.B.16
-
15
-
-
23944493717
-
11beta-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice
-
Hermanowski-Vosatka A., Balkovec J.M., Cheng K., Chen H.Y., Hernandez M., Koo G.C., Le Grand C.B., Li Z., Metzger J.M., Mundt S.S., Noonan H., Nunes C.N., Olson S.H., Pikounis B., Ren N., Robertson N., Schaeffer J.M., Shah K., Springer M.S., Strack A.M., Strowski M., Wu K., Wu T., Xiao J., Zhang B.B., Wright S.D., and Thieringer R. 11beta-HSD1 inhibition ameliorates metabolic syndrome and prevents progression of atherosclerosis in mice. J. Exp. Med. 202 (2005) 517-527
-
(2005)
J. Exp. Med.
, vol.202
, pp. 517-527
-
-
Hermanowski-Vosatka, A.1
Balkovec, J.M.2
Cheng, K.3
Chen, H.Y.4
Hernandez, M.5
Koo, G.C.6
Le Grand, C.B.7
Li, Z.8
Metzger, J.M.9
Mundt, S.S.10
Noonan, H.11
Nunes, C.N.12
Olson, S.H.13
Pikounis, B.14
Ren, N.15
Robertson, N.16
Schaeffer, J.M.17
Shah, K.18
Springer, M.S.19
Strack, A.M.20
Strowski, M.21
Wu, K.22
Wu, T.23
Xiao, J.24
Zhang, B.B.25
Wright, S.D.26
Thieringer, R.27
more..
-
16
-
-
33644922002
-
11beta-hydroxysteroid dehydrogenase type 1: a potential therapeutic target for the control of local glucocorticoid concentrations
-
Odermatt A. 11beta-hydroxysteroid dehydrogenase type 1: a potential therapeutic target for the control of local glucocorticoid concentrations. Curr. Enzyme Inhib. 1 (2005) 97-105
-
(2005)
Curr. Enzyme Inhib.
, vol.1
, pp. 97-105
-
-
Odermatt, A.1
-
17
-
-
0344844573
-
A rapid screening assay for inhibitors of 11beta-hydroxysteroid dehydrogenases (11beta-HSD): flavanone selectively inhibits 11beta-HSD1 reductase activity
-
Schweizer R.A., Atanasov A.G., Frey B.M., and Odermatt A. A rapid screening assay for inhibitors of 11beta-hydroxysteroid dehydrogenases (11beta-HSD): flavanone selectively inhibits 11beta-HSD1 reductase activity. Mol. Cell. Endocrinol. 212 (2003) 41-49
-
(2003)
Mol. Cell. Endocrinol.
, vol.212
, pp. 41-49
-
-
Schweizer, R.A.1
Atanasov, A.G.2
Frey, B.M.3
Odermatt, A.4
-
19
-
-
3342998410
-
Hexose-6-phosphate dehydrogenase determines the reaction direction of 11beta-hydroxysteroid dehydrogenase type 1 as an oxoreductase
-
Atanasov A.G., Nashev L.G., Schweizer R.A., Frick C., and Odermatt A. Hexose-6-phosphate dehydrogenase determines the reaction direction of 11beta-hydroxysteroid dehydrogenase type 1 as an oxoreductase. FEBS Lett. 571 (2004) 129-133
-
(2004)
FEBS Lett.
, vol.571
, pp. 129-133
-
-
Atanasov, A.G.1
Nashev, L.G.2
Schweizer, R.A.3
Frick, C.4
Odermatt, A.5
-
20
-
-
0029899120
-
Evidence using a green fluorescent protein-glucocorticoid receptor chimera that the Ran/TC4 GTPase mediates an essential function independent of nuclear protein import
-
Carey K.L., Richards S.A., Lounsbury K.M., and Macara I.G. Evidence using a green fluorescent protein-glucocorticoid receptor chimera that the Ran/TC4 GTPase mediates an essential function independent of nuclear protein import. J. Cell Biol. 133 (1996) 985-996
-
(1996)
J. Cell Biol.
, vol.133
, pp. 985-996
-
-
Carey, K.L.1
Richards, S.A.2
Lounsbury, K.M.3
Macara, I.G.4
-
21
-
-
0033214482
-
The N-terminal anchor sequences of 11beta-hydroxysteroid dehydrogenases determine their orientation in the endoplasmic reticulum membrane
-
Odermatt A., Arnold P., Stauffer A., Frey B.M., and Frey F.J. The N-terminal anchor sequences of 11beta-hydroxysteroid dehydrogenases determine their orientation in the endoplasmic reticulum membrane. J. Biol. Chem. 274 (1999) 28762-28770
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 28762-28770
-
-
Odermatt, A.1
Arnold, P.2
Stauffer, A.3
Frey, B.M.4
Frey, F.J.5
-
22
-
-
23844467917
-
Comparative enzymology of 11beta-hydroxysteroid dehydrogenase type 1 from six species
-
Arampatzis S., Kadereit B., Schuster D., Balazs Z., Schweizer R.A., Frey F.J., Langer T., and Odermatt A. Comparative enzymology of 11beta-hydroxysteroid dehydrogenase type 1 from six species. J. Mol. Endocrinol. 35 (2005) 89-101
-
(2005)
J. Mol. Endocrinol.
, vol.35
, pp. 89-101
-
-
Arampatzis, S.1
Kadereit, B.2
Schuster, D.3
Balazs, Z.4
Schweizer, R.A.5
Frey, F.J.6
Langer, T.7
Odermatt, A.8
-
23
-
-
17444391240
-
Dehydroepiandrosterone inhibits the amplification of glucocorticoid action in adipose tissue
-
Apostolova G., Schweizer R.A., Balazs Z., Kostadinova R.M., and Odermatt A. Dehydroepiandrosterone inhibits the amplification of glucocorticoid action in adipose tissue. Am. J. Physiol. Endocrinol. Metab. 288 (2005) E957-E964
-
(2005)
Am. J. Physiol. Endocrinol. Metab.
, vol.288
-
-
Apostolova, G.1
Schweizer, R.A.2
Balazs, Z.3
Kostadinova, R.M.4
Odermatt, A.5
-
24
-
-
33745221417
-
The discovery of new 11b-hydroxysteroid dehydrogenase type 1 inhibitors by common feature pharmacophore modeling and virtual screening
-
Schuster D., Maurer E.M., Laggner C., Nashev L.G., Wilckens T., Langer T., and Odermatt A. The discovery of new 11b-hydroxysteroid dehydrogenase type 1 inhibitors by common feature pharmacophore modeling and virtual screening. J. Med. Chem. 49 (2006) 3454-3466
-
(2006)
J. Med. Chem.
, vol.49
, pp. 3454-3466
-
-
Schuster, D.1
Maurer, E.M.2
Laggner, C.3
Nashev, L.G.4
Wilckens, T.5
Langer, T.6
Odermatt, A.7
-
25
-
-
24044524673
-
Is coffee a functional food?
-
Dorea J.G., and da Costa T.H. Is coffee a functional food?. Br. J. Nutr. 93 (2005) 773-782
-
(2005)
Br. J. Nutr.
, vol.93
, pp. 773-782
-
-
Dorea, J.G.1
da Costa, T.H.2
-
26
-
-
0346727464
-
Coffee consumption and risk for type 2 diabetes mellitus
-
Salazar-Martinez E., Willett W.C., Ascherio A., Manson J.E., Leitzmann M.F., Stampfer M.J., and Hu F.B. Coffee consumption and risk for type 2 diabetes mellitus. Ann. Intern. Med. 140 (2004) 1-8
-
(2004)
Ann. Intern. Med.
, vol.140
, pp. 1-8
-
-
Salazar-Martinez, E.1
Willett, W.C.2
Ascherio, A.3
Manson, J.E.4
Leitzmann, M.F.5
Stampfer, M.J.6
Hu, F.B.7
-
27
-
-
23944499104
-
Coffee, tea and diabetes: the role of weight loss and caffeine
-
Greenberg J.A., Axen K.V., Schnoll R., and Boozer C.N. Coffee, tea and diabetes: the role of weight loss and caffeine. Int. J. Obes. (Lond.) 29 (2005) 1121-1129
-
(2005)
Int. J. Obes. (Lond.)
, vol.29
, pp. 1121-1129
-
-
Greenberg, J.A.1
Axen, K.V.2
Schnoll, R.3
Boozer, C.N.4
-
28
-
-
33646419777
-
The glucose intolerance induced by caffeinated coffee ingestion is less pronounced than that due to alkaloid caffeine in men
-
Battram D.S., Arthur R., Weekes A., and Graham T.E. The glucose intolerance induced by caffeinated coffee ingestion is less pronounced than that due to alkaloid caffeine in men. J. Nutr. 136 (2006) 1276-1280
-
(2006)
J. Nutr.
, vol.136
, pp. 1276-1280
-
-
Battram, D.S.1
Arthur, R.2
Weekes, A.3
Graham, T.E.4
-
29
-
-
13444293166
-
A chlorogenic acid-induced increase in GLP-1 production may mediate the impact of heavy coffee consumption on diabetes risk
-
McCarty M.F. A chlorogenic acid-induced increase in GLP-1 production may mediate the impact of heavy coffee consumption on diabetes risk. Med. Hypoth. 64 (2005) 848-853
-
(2005)
Med. Hypoth.
, vol.64
, pp. 848-853
-
-
McCarty, M.F.1
-
30
-
-
0036895683
-
Beneficial role of dietary phytoestrogens in obesity and diabetes
-
Bhathena S.J., and Velasquez M.T. Beneficial role of dietary phytoestrogens in obesity and diabetes. Am. J. Clin. Nutr. 76 (2002) 1191-1201
-
(2002)
Am. J. Clin. Nutr.
, vol.76
, pp. 1191-1201
-
-
Bhathena, S.J.1
Velasquez, M.T.2
-
32
-
-
17844403523
-
Tissue-specific Cushing's syndrome uncovers a new target in treating the metabolic syndrome-11beta-hydroxysteroid dehydrogenase type 1
-
Stewart P.M. Tissue-specific Cushing's syndrome uncovers a new target in treating the metabolic syndrome-11beta-hydroxysteroid dehydrogenase type 1. Clin. Med. 5 (2005) 142-146
-
(2005)
Clin. Med.
, vol.5
, pp. 142-146
-
-
Stewart, P.M.1
-
33
-
-
33745125766
-
Comparison of a homology model and the crystallographic structure of human 11beta-hydroxysteroid dehydrogenase type 1 (11betaHSD1) in a structure-based identification of inhibitors
-
Miguet L., Zhang Z., Barbier M., and Grigorov M.G. Comparison of a homology model and the crystallographic structure of human 11beta-hydroxysteroid dehydrogenase type 1 (11betaHSD1) in a structure-based identification of inhibitors. J. Comput. Aided Mol. Des. 20 (2006) 67-81
-
(2006)
J. Comput. Aided Mol. Des.
, vol.20
, pp. 67-81
-
-
Miguet, L.1
Zhang, Z.2
Barbier, M.3
Grigorov, M.G.4
|