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Volumn 109, Issue 1, 2014, Pages 8-14

Protective effect of quercetin on hyperglycemia, oxidative stress and DNA damage in alloxan induced type 2 diabetic mice

Author keywords

DNA damage; GLUT4; Hyperglycemia; Quercetin; Type 2 diabetes

Indexed keywords

ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ALLOXAN; ASPARTATE AMINOTRANSFERASE; CATALASE; CREATININE; FRUCTOSE BISPHOSPHATASE; GLUCOSE; GLUCOSE 6 PHOSPHATASE; GLUCOSE TRANSPORTER 4; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HEXOKINASE; QUERCETIN; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UREA;

EID: 84904244316     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2014.06.005     Document Type: Article
Times cited : (149)

References (44)
  • 1
    • 0021318441 scopus 로고
    • Catalase in vitro
    • H. Aebi Catalase in vitro Methods Enzymol 105 1984 121 126
    • (1984) Methods Enzymol , vol.105 , pp. 121-126
    • Aebi, H.1
  • 2
    • 0027171266 scopus 로고
    • Oxidants, antioxidants, and the degenerative diseases of aging
    • B.N. Ames, M.K. Shigenaga, and T.M. Hgent Oxidants, antioxidants, and the degenerative diseases of aging Proc Natl Acad Sci U S A 90 1993 7915 7922
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 7915-7922
    • Ames, B.N.1    Shigenaga, M.K.2    Hgent, T.M.3
  • 3
    • 84875433990 scopus 로고    scopus 로고
    • A review of quercetin: Antioxidant and anticancer properties
    • S. Baghel, N. Shrivastava, and S. Baghel A review of quercetin: antioxidant and anticancer properties World J Pharm Pharm Sci 1 2012 146 160
    • (2012) World J Pharm Pharm Sci , vol.1 , pp. 146-160
    • Baghel, S.1    Shrivastava, N.2    Baghel, S.3
  • 4
    • 84879017956 scopus 로고    scopus 로고
    • Quercetin induces insulin secretion by direct activation of L-type calcium channels in pancreatic beta cells
    • G. Bardy, A. Virsolvy, J.F. Quignard, M.A. Ravier, G. Bertrand, and S. Dalle et al. Quercetin induces insulin secretion by direct activation of L-type calcium channels in pancreatic beta cells Br J Pharmacol 169 2013 1102 1113
    • (2013) Br J Pharmacol , vol.169 , pp. 1102-1113
    • Bardy, G.1    Virsolvy, A.2    Quignard, J.F.3    Ravier, M.A.4    Bertrand, G.5    Dalle, S.6
  • 5
    • 0032913309 scopus 로고    scopus 로고
    • Role of oxidative stress in diabetic complications: A new perspective on an old paradigm
    • J.W. Baynes, and S.R. Thorpe Role of oxidative stress in diabetic complications: a new perspective on an old paradigm Diabetes 48 1999 1 9
    • (1999) Diabetes , vol.48 , pp. 1-9
    • Baynes, J.W.1    Thorpe, S.R.2
  • 6
    • 0017872475 scopus 로고
    • Microsomal lipid peroxidation
    • J.A. Beuge, and S.D. Aust Microsomal lipid peroxidation Methods Enzymol 52 1978 302 310
    • (1978) Methods Enzymol , vol.52 , pp. 302-310
    • Beuge, J.A.1    Aust, S.D.2
  • 7
    • 84875976270 scopus 로고    scopus 로고
    • Insulin signalling in type 2 diabetes: Experimental and modelling analyses reveal mechanisms of insulin resistance in human adipocytes
    • C. Brannmark, E. Nyman, S. Fagerholm, L. Bergenholm, E.M. Ekstrand, and G. Cedersund et al. Insulin signalling in type 2 diabetes: experimental and modelling analyses reveal mechanisms of insulin resistance in human adipocytes J Biol Chem 288 2013 9867 9880
    • (2013) J Biol Chem , vol.288 , pp. 9867-9880
    • Brannmark, C.1    Nyman, E.2    Fagerholm, S.3    Bergenholm, L.4    Ekstrand, E.M.5    Cedersund, G.6
  • 8
    • 0006857425 scopus 로고
    • The association of particulate fractions of brain and other tissue homogenates
    • R.K. Crane, and A. Sols The association of particulate fractions of brain and other tissue homogenates J Biol Chem 203 1953 273 292
    • (1953) J Biol Chem , vol.203 , pp. 273-292
    • Crane, R.K.1    Sols, A.2
  • 9
    • 79960082627 scopus 로고    scopus 로고
    • Animals models for studying diabetes mellitus
    • E.U. Etuk Animals models for studying diabetes mellitus Agric Biol J N Am 1 2010 130 134
    • (2010) Agric Biol J N Am , vol.1 , pp. 130-134
    • Etuk, E.U.1
  • 10
    • 0000204227 scopus 로고
    • A metabolic adaptation in higher animals: The study of metabolic pathways by means of metabolic adaptations
    • R.A. Freedland, and A.E. Harper A metabolic adaptation in higher animals: the study of metabolic pathways by means of metabolic adaptations J Biol Chem 231 1959 1350 1354
    • (1959) J Biol Chem , vol.231 , pp. 1350-1354
    • Freedland, R.A.1    Harper, A.E.2
  • 11
    • 34347235801 scopus 로고    scopus 로고
    • Inhibitory activity of flavonoids on the lens aldose reductase of healthy and diabetic rats
    • M.T. Goodarzi, F. Zal, M. Malakooti, M.R. Safari, and S. Sadeghian Inhibitory activity of flavonoids on the lens aldose reductase of healthy and diabetic rats Acta Med Iran 44 2006 41 45
    • (2006) Acta Med Iran , vol.44 , pp. 41-45
    • Goodarzi, M.T.1    Zal, F.2    Malakooti, M.3    Safari, M.R.4    Sadeghian, S.5
  • 12
    • 0016275313 scopus 로고
    • Glutathione S-transferase: The first enzymatic step in mercapturic acid formation
    • W.H. Habig, M.J. Pabst, and W.B. Jokoby Glutathione S-transferase: the first enzymatic step in mercapturic acid formation J Biol Chem 249 1974 7130 7139
    • (1974) J Biol Chem , vol.249 , pp. 7130-7139
    • Habig, W.H.1    Pabst, M.J.2    Jokoby, W.B.3
  • 13
    • 33947596679 scopus 로고    scopus 로고
    • The GLUT4 glucose transporter
    • S. Huang, and M.P. Czech The GLUT4 glucose transporter Cell Metab 5 2007 237 252
    • (2007) Cell Metab , vol.5 , pp. 237-252
    • Huang, S.1    Czech, M.P.2
  • 14
    • 0025096104 scopus 로고
    • Autooxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose
    • J.V. Hunt, C.C. Smith, and S.P. Wolff Autooxidative glycosylation and possible involvement of peroxides and free radicals in LDL modification by glucose Diabetes 39 1990 1420 1424
    • (1990) Diabetes , vol.39 , pp. 1420-1424
    • Hunt, J.V.1    Smith, C.C.2    Wolff, S.P.3
  • 15
    • 34250618361 scopus 로고    scopus 로고
    • Characterization of inhibitors of postprandial hyperglycemia from the leaves of Nerium indicum
    • A. Ishikawa, H. Yamashita, M. Hiemori, E. Inagaki, M. Kimoto, and M. Okamoto et al. Characterization of inhibitors of postprandial hyperglycemia from the leaves of Nerium indicum J Nutr Sci Vitaminol 53 2007 166 173
    • (2007) J Nutr Sci Vitaminol , vol.53 , pp. 166-173
    • Ishikawa, A.1    Yamashita, H.2    Hiemori, M.3    Inagaki, E.4    Kimoto, M.5    Okamoto, M.6
  • 16
    • 0027979385 scopus 로고
    • Hydroperoxide induced oxidative stress impairs heart muscle cell carbohydrate metabolism
    • D.R. Janero, D. Hreniuk, and H.M. Sharif Hydroperoxide induced oxidative stress impairs heart muscle cell carbohydrate metabolism Am J Physiol 266 1994 C179 C188
    • (1994) Am J Physiol , vol.266
    • Janero, D.R.1    Hreniuk, D.2    Sharif, H.M.3
  • 17
    • 84894815681 scopus 로고    scopus 로고
    • Quercetin reduces obesity-associated ATM infiltration and inflammation in mice: A mechanism including AMPKα1/SIRT1
    • D. Jing, Z. Xian, Z. Lei, B. Hui-Xi, N. Xu, and B. Bin et al. Quercetin reduces obesity-associated ATM infiltration and inflammation in mice: a mechanism including AMPKα1/SIRT1 J Lipid Res 55 2014 363 374
    • (2014) J Lipid Res , vol.55 , pp. 363-374
    • Jing, D.1    Xian, Z.2    Lei, Z.3    Hui-Xi, B.4    Xu, N.5    Bin, B.6
  • 18
    • 79956271261 scopus 로고    scopus 로고
    • Comparison of antioxidant potential and rat intestinal α-glucosidases inhibitory activities of quercetin, rutin, and isoquercetin
    • S.H. Jo, E.H. Ka, H.S. Lee, E. Apostolidis, H.D. Jang, and Y.I. Kwon Comparison of antioxidant potential and rat intestinal α-glucosidases inhibitory activities of quercetin, rutin, and isoquercetin Int J Appl Res Nat Prod 2 2009 52 60
    • (2009) Int J Appl Res Nat Prod , vol.2 , pp. 52-60
    • Jo, S.H.1    Ka, E.H.2    Lee, H.S.3    Apostolidis, E.4    Jang, H.D.5    Kwon, Y.I.6
  • 19
    • 0016151122 scopus 로고
    • Bromobenzene induced liver necrosis. Protective role of glutathione and evidence for 3,4 bromobenzene oxide as the hepatotoxic intermediate
    • D.J. Jollow, J.R. Mitchell, N. Zampalione, and J.R. Gillete Bromobenzene induced liver necrosis. Protective role of glutathione and evidence for 3,4 bromobenzene oxide as the hepatotoxic intermediate Pharmacology 11 1974 151 169
    • (1974) Pharmacology , vol.11 , pp. 151-169
    • Jollow, D.J.1    Mitchell, J.R.2    Zampalione, N.3    Gillete, J.R.4
  • 20
    • 0031962808 scopus 로고    scopus 로고
    • Effects of naturally-occurring flavonoids and bio-flavonoids on epidermal cyclooxygenase from guinea-pigs
    • H.P. Kim, I. Mani, and V.A. Ziboh Effects of naturally-occurring flavonoids and bio-flavonoids on epidermal cyclooxygenase from guinea-pigs Prostaglandins Leukot Essent Fatty Acids 58 1998 17 24
    • (1998) Prostaglandins Leukot Essent Fatty Acids , vol.58 , pp. 17-24
    • Kim, H.P.1    Mani, I.2    Ziboh, V.A.3
  • 21
    • 79956273349 scopus 로고    scopus 로고
    • Quercetin attenuates fasting and postprandial hyperglycemia in animal models of diabetes mellitus
    • J.H. Kim, M.J. Kang, H.N. Choi, S.M. Jeong, Y.M. Lee, and J.I. Kim Quercetin attenuates fasting and postprandial hyperglycemia in animal models of diabetes mellitus Nutr Res Pract 5 2011 107 111
    • (2011) Nutr Res Pract , vol.5 , pp. 107-111
    • Kim, J.H.1    Kang, M.J.2    Choi, H.N.3    Jeong, S.M.4    Lee, Y.M.5    Kim, J.I.6
  • 22
    • 77049203740 scopus 로고
    • Estimation of plasma phosphatase by determination of hydrolysed phenol with amino-antipyrine
    • R.N. Kind, and E.J. King Estimation of plasma phosphatase by determination of hydrolysed phenol with amino-antipyrine J Clin Pathol 7 1954 322
    • (1954) J Clin Pathol , vol.7 , pp. 322
    • Kind, R.N.1    King, E.J.2
  • 23
    • 84861444859 scopus 로고    scopus 로고
    • Regulation of glucose transport by insulin: Traffic control of GLUT4
    • D. Leto, and A.R. Saltiel Regulation of glucose transport by insulin: traffic control of GLUT4 Nat Rev Mol Cell Biol 13 2012 383 396
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 383-396
    • Leto, D.1    Saltiel, A.R.2
  • 24
    • 0035006715 scopus 로고    scopus 로고
    • Synthesis of flavonoids and their effects on aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues
    • S.S. Lim, S.H. Jung, J. Ji, K.H. Shin, and S.R. Keum Synthesis of flavonoids and their effects on aldose reductase and sorbitol accumulation in streptozotocin-induced diabetic rat tissues J Pharm Pharmacol 53 2001 653 668
    • (2001) J Pharm Pharmacol , vol.53 , pp. 653-668
    • Lim, S.S.1    Jung, S.H.2    Ji, J.3    Shin, K.H.4    Keum, S.R.5
  • 25
    • 0024247134 scopus 로고
    • Anti-inflammatory activity of benzopyrones that are inhibitors of cyclo- and lipo-oxygenase
    • R. Loggia, E. Raqazzi, A. Tubaro, G. Fassina, and R. Vertua Anti-inflammatory activity of benzopyrones that are inhibitors of cyclo- and lipo-oxygenase Pharmacol Res Commun 20 1988 91 94
    • (1988) Pharmacol Res Commun , vol.20 , pp. 91-94
    • Loggia, R.1    Raqazzi, E.2    Tubaro, A.3    Fassina, G.4    Vertua, R.5
  • 26
    • 0016272750 scopus 로고
    • The involvement of the superoxide radical in the auto-oxidation of pyrogallol and a convenient assay for superoxide dismutase
    • S. Marklund, and G. Marklund The involvement of the superoxide radical in the auto-oxidation of pyrogallol and a convenient assay for superoxide dismutase Eur J Biochem 47 1947 469 474
    • (1947) Eur J Biochem , vol.47 , pp. 469-474
    • Marklund, S.1    Marklund, G.2
  • 27
    • 0025540553 scopus 로고
    • Free radical generation by early glycation products: A mechanism for accelerated atherogenesis in diabetes
    • C.J. Mullarkey, D. Edelstein, and M. Brownlee Free radical generation by early glycation products: a mechanism for accelerated atherogenesis in diabetes Biochem Biophys Res Commun 173 1990 932 939
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 932-939
    • Mullarkey, C.J.1    Edelstein, D.2    Brownlee, M.3
  • 29
    • 0000674033 scopus 로고
    • Photometric adaptation of Somogyi method for the determination of glucose
    • N.A. Nelson Photometric adaptation of Somogyi method for the determination of glucose J Biol Chem 153 1994 375
    • (1994) J Biol Chem , vol.153 , pp. 375
    • Nelson, N.A.1
  • 30
    • 0023770113 scopus 로고
    • Free radicals and diabetes
    • L.W. Oberley Free radicals and diabetes Free Radic Biol Med 5 1988 113 124
    • (1988) Free Radic Biol Med , vol.5 , pp. 113-124
    • Oberley, L.W.1
  • 31
    • 0030042738 scopus 로고    scopus 로고
    • Oxidative stress and insulin action: Is there a relationship?
    • G. Paolisso, and D. Giugliano Oxidative stress and insulin action: is there a relationship? Diabetologia 39 1996 357 363
    • (1996) Diabetologia , vol.39 , pp. 357-363
    • Paolisso, G.1    Giugliano, D.2
  • 32
    • 0033913213 scopus 로고    scopus 로고
    • Signaling pathways in insulin action: Molecular targets of insulin resistance
    • J.E. Pessin, and A.R. Salteil Signaling pathways in insulin action: molecular targets of insulin resistance J Clin Invest 106 2000 165 169
    • (2000) J Clin Invest , vol.106 , pp. 165-169
    • Pessin, J.E.1    Salteil, A.R.2
  • 33
    • 66349129125 scopus 로고
    • A colorimetric method for the determination of serum glutamic oxaloacetic and glutamic pyruvic transaminases
    • S. Reitman, and S. Frankel A colorimetric method for the determination of serum glutamic oxaloacetic and glutamic pyruvic transaminases Am J Clin Pathol 28 1957 56 63
    • (1957) Am J Clin Pathol , vol.28 , pp. 56-63
    • Reitman, S.1    Frankel, S.2
  • 34
    • 33645765312 scopus 로고    scopus 로고
    • Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress
    • P. Rolo, and M. Palmeira Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress Toxicol Appl Pharmacol 212 2006 167 178
    • (2006) Toxicol Appl Pharmacol , vol.212 , pp. 167-178
    • Rolo, P.1    Palmeira, M.2
  • 36
    • 0014428865 scopus 로고
    • Estimation of total, protein-bound and non-protein sulfhydryl groups in tissues with Ellman's reagent
    • J. Sedalk, and R.H. Lindsay Estimation of total, protein-bound and non-protein sulfhydryl groups in tissues with Ellman's reagent Anal Biochem 25 1968 192 205
    • (1968) Anal Biochem , vol.25 , pp. 192-205
    • Sedalk, J.1    Lindsay, R.H.2
  • 37
    • 0008172527 scopus 로고
    • Hexokinase, glucose-6-phosphatase and phosphorylase levels in hereditarily obese-hyperglycemic mice
    • K.H. Shull, A. James, and M. Jean Hexokinase, glucose-6-phosphatase and phosphorylase levels in hereditarily obese-hyperglycemic mice Arch Biochem Biophys 62 1956 210 216
    • (1956) Arch Biochem Biophys , vol.62 , pp. 210-216
    • Shull, K.H.1    James, A.2    Jean, M.3
  • 38
    • 0023919963 scopus 로고
    • A simple technique for quantitation of low levels of DNA damage in individual cells
    • N.P. Singh, M.T. McCoy, R.R. Tice, and E.L. Schneider A simple technique for quantitation of low levels of DNA damage in individual cells Exp Cell Res 175 1988 184 191
    • (1988) Exp Cell Res , vol.175 , pp. 184-191
    • Singh, N.P.1    McCoy, M.T.2    Tice, R.R.3    Schneider, E.L.4
  • 40
    • 0033556016 scopus 로고    scopus 로고
    • Akt-2 binds to Glut4-containing vesicles and phosphorylates their component proteins in response to insulin
    • A.K. Tatyana, and V.K. Konstantin Akt-2 binds to Glut4-containing vesicles and phosphorylates their component proteins in response to insulin J Biol Chem 274 1999 1458 1464
    • (1999) J Biol Chem , vol.274 , pp. 1458-1464
    • Tatyana, A.K.1    Konstantin, V.K.2
  • 41
    • 3342922088 scopus 로고
    • A microcolorimetric method for the determination of inorganic phosphorus
    • H.H. Tausky, and E.A. Shorr A microcolorimetric method for the determination of inorganic phosphorus J Biol Chem 202 1953 675 685
    • (1953) J Biol Chem , vol.202 , pp. 675-685
    • Tausky, H.H.1    Shorr, E.A.2
  • 42
    • 0003072603 scopus 로고
    • Determination of glucose in blood using glucose oxidase with an alternate oxygen acceptor
    • P. Trinder Determination of glucose in blood using glucose oxidase with an alternate oxygen acceptor Ann Clin Biochem 6 1969 24 27
    • (1969) Ann Clin Biochem , vol.6 , pp. 24-27
    • Trinder, P.1
  • 43
    • 0031871542 scopus 로고    scopus 로고
    • Oxidative stress causes depolarization and calcium uptake in the rat insulinoma cell RINm5F
    • M.A. Wahl, I. Koopman, and H.P.T. Ammon Oxidative stress causes depolarization and calcium uptake in the rat insulinoma cell RINm5F Exp Clin Endocrinol Diabetes 106 1998 173 177
    • (1998) Exp Clin Endocrinol Diabetes , vol.106 , pp. 173-177
    • Wahl, M.A.1    Koopman, I.2    Ammon, H.P.T.3
  • 44
    • 0027279232 scopus 로고
    • Diabetes mellitus and free radicals. Free radicals, transition metals and oxidative stress in the aetiology of diabetes mellitus and complications
    • S.P. Wolff Diabetes mellitus and free radicals. Free radicals, transition metals and oxidative stress in the aetiology of diabetes mellitus and complications Br Med Bull 49 1993 642 652
    • (1993) Br Med Bull , vol.49 , pp. 642-652
    • Wolff, S.P.1


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