메뉴 건너뛰기




Volumn 22, Issue 8, 2013, Pages 1063-1079

Rutin: Therapeutic potential and recent advances in drug delivery

Author keywords

Antioxidant; Bioavailability; Bioflavonoids; Rutin

Indexed keywords

AMPICILLIN; GLYCYRRHETINIC ACID PHOSPHOLIPID COMPLEX; LEVOFLOXACIN; OFLOXACIN; PIROXICAM BETA CYCLODEXTRIN; QUERCETIN; RUTOSIDE;

EID: 84880241949     PISSN: 13543784     EISSN: 17447658     Source Type: Journal    
DOI: 10.1517/13543784.2013.805744     Document Type: Article
Times cited : (311)

References (109)
  • 1
    • 0034836506 scopus 로고    scopus 로고
    • Flavonoids: A review of probable mechanisms of action and potential applications
    • Nijveldt RJ, van Nood E, van Hoorn DEC, et al. Flavonoids: A review of probable mechanisms of action and potential applications. Am J Clin Nutr 2001;74:418-25
    • (2001) Am J Clin Nutr , vol.74 , pp. 418-425
    • Nijveldt, R.J.1    Van Nood, E.2    Van Hoorn, D.E.C.3
  • 2
    • 0035076924 scopus 로고    scopus 로고
    • Bioflavonoids classification, pharmacological, biochemical effects and therapeutic potential
    • Narayana KR, Reddy MS, Chaluvadi MR, et al. Bioflavonoids classification, pharmacological, biochemical effects and therapeutic potential. Ind J Pharmcol 2001;33:2-16
    • (2001) Ind J Pharmcol , vol.33 , pp. 2-16
    • Narayana, K.R.1    Reddy, M.S.2    Chaluvadi, M.R.3
  • 4
    • 0019841431 scopus 로고
    • Inhibitory effects of flavonoids on xanthine oxidase
    • Petkov E, Nickdor N, Uzunov P. Inhibitory effects of flavonoids on xanthine oxidase. Planta Med 1981;43:183-7
    • (1981) Planta Med , vol.43 , pp. 183-187
    • Petkov, E.1    Nickdor, N.2    Uzunov, P.3
  • 6
    • 33846582444 scopus 로고    scopus 로고
    • The anti-inflammatory flavones quercetin and kaempferol cause inhibition of inducible nitric oxide synthase, cyclooxygenase-2 and reactive C-protein, and down-regulation of the nuclear factor kappa B pathway in Chang Liver cells
    • Garcia-Mediavilla V, Crespo I, Collado PS, et al. The anti-inflammatory flavones quercetin and kaempferol cause inhibition of inducible nitric oxide synthase, cyclooxygenase-2 and reactive C-protein, and down-regulation of the nuclear factor kappa B pathway in Chang Liver cells. Eur J Pharmacol 2007;557:221-9
    • (2007) Eur J Pharmacol , vol.557 , pp. 221-229
    • Garcia-Mediavilla, V.1    Crespo, I.2    Collado, P.S.3
  • 7
    • 0027291905 scopus 로고
    • Intake of potentially anticarcinogenic flavonoids and their determinants in adults in the Netherlands
    • Hertog MGL, Hollman PCH, Katan MB, et al. Intake of potentially anticarcinogenic flavonoids and their determinants in adults in the Netherlands. Nutr Cancer 1993;20:21-9
    • (1993) Nutr Cancer , vol.20 , pp. 21-29
    • Hertog, M.G.L.1    Hollman, P.C.H.2    Katan, M.B.3
  • 8
    • 0024604665 scopus 로고
    • Antiproliferative effects of synthetic and naturally occurring flavonoids on turner cells of the human breast carcinoma cell line, 2R- 75-1
    • Hirano T, Oka K, Akiba M. Antiproliferative effects of synthetic and naturally occurring flavonoids on turner cells of the human breast carcinoma cell line, 2R- 75-1. Res Commun Chem Pahol Pharmacol 1989;64:69-78
    • (1989) Res Commun Chem Pahol Pharmacol , vol.64 , pp. 69-78
    • Hirano, T.1    Oka, K.2    Akiba, M.3
  • 9
    • 10244232942 scopus 로고    scopus 로고
    • Lack of tumour-Promoting effects of flavonoids: Studies on rat liver preneostatic foci and on in vivo and in vitro gap junctional inter cellular communication
    • Catherine C, Malc S, Esther HL, et al. Lack of tumour-Promoting effects of flavonoids: Studies on rat liver preneostatic foci and on in vivo and in vitro gap junctional inter cellular communication. Nutr Cancer 1996;26:251-63
    • (1996) Nutr Cancer , vol.26 , pp. 251-263
    • Catherine, C.1    Malc, S.2    Esther, H.L.3
  • 10
    • 36949043890 scopus 로고
    • Antimicrobial activity of flavonoids from leaves of chinese herb
    • Gabor M, Eperjessy E. Antimicrobial activity of flavonoids from leaves of chinese herb. Nature 1966;212:1273-9
    • (1966) Nature , vol.212 , pp. 1273-1279
    • Gabor, M.1    Eperjessy, E.2
  • 11
    • 0030965816 scopus 로고    scopus 로고
    • Antimicrobial activity of flavonoids from leaves of Tagetes minuta
    • Tereschuk ML, Riera MVQ, Casteo GR, et al. Antimicrobial activity of flavonoids from leaves of Tagetes minuta. J Ethnopharmacol 1997;56:227-36
    • (1997) J Ethnopharmacol , vol.56 , pp. 227-236
    • Tereschuk, M.L.1    Riera, M.V.Q.2    Casteo, G.R.3
  • 12
    • 0027442217 scopus 로고
    • Inhibition of HIV infection by flavonoids
    • Mahmood N, Pizza C, Aquino R, et al. Inhibition of HIV infection by flavonoids. Antiviral Res 1993;22:189-97
    • (1993) Antiviral Res , vol.22 , pp. 189-197
    • Mahmood, N.1    Pizza, C.2    Aquino, R.3
  • 13
    • 0000708904 scopus 로고
    • In vitro anti-HIV activity of flavonoids isolated from Garcinia multifolia
    • Tripathi VD, Rastogi RP. In vitro anti-HIV activity of flavonoids isolated from Garcinia multifolia. J Sci Indian Res 1981;40:116-21
    • (1981) J Sci Indian Res , vol.40 , pp. 116-121
    • Tripathi, V.D.1    Rastogi, R.P.2
  • 14
    • 0005582254 scopus 로고    scopus 로고
    • Effect of flavonoid compounds on the immune system
    • Kais N, Rahman MM, Rashid MA, et al. Effect of flavonoid compounds on the immune system. Fitoterapia 1996;67:554-61
    • (1996) Fitoterapia , vol.67 , pp. 554-561
    • Kais, N.1    Rahman, M.M.2    Rashid, M.A.3
  • 15
    • 0031708667 scopus 로고    scopus 로고
    • Effect of plant flavonoids on immune and inflammatory cell function
    • Middleton E Jr. Effect of plant flavonoids on immune and inflammatory cell function. Adv Exp Med Bio 1998;439:175-82
    • (1998) Adv Exp Med Bio , vol.439 , pp. 175-182
    • Middleton Jr., E.1
  • 16
    • 0005524734 scopus 로고
    • Clinical study of effect of SU-88 on gastric ulcer combination of treatment
    • Hirasawa T, Shoji T, Hoshino E, et al. Clinical study of effect of SU-88 on gastric ulcer combination of treatment. Japan Pharmacol Ther 1982;10:5
    • (1982) Japan Pharmacol Ther , vol.10 , pp. 5
    • Hirasawa, T.1    Shoji, T.2    Hoshino, E.3
  • 17
    • 0019954632 scopus 로고
    • Clinical evaluation of SU-88 on pepticulcer
    • Gomi K, Kwayama H, Abe M, et al. Clinical evaluation of SU-88 on pepticulcer. Japan Pharmacol Ther 1982;10:1
    • (1982) Japan Pharmacol Ther , vol.10 , pp. 1
    • Gomi, K.1    Kwayama, H.2    Abe, M.3
  • 18
    • 21144460399 scopus 로고
    • The flavonoids: New perspectives in biological activities and therapeutics
    • Bombardelli E, Morazzoni P. The flavonoids: New perspectives in biological activities and therapeutics. Chim Oggi 1993;11:25-8
    • (1993) Chim Oggi , vol.11 , pp. 25-28
    • Bombardelli, E.1    Morazzoni, P.2
  • 19
    • 19944394500 scopus 로고    scopus 로고
    • The rutin/beta-cyclodextrin interactions in fully aqueous solution: Spectroscopic studies and biological assays
    • Calabro ML, Tommasini S, Donato P, et al. The rutin/beta-cyclodextrin interactions in fully aqueous solution: Spectroscopic studies and biological assays. J Pharm Biomed Anal 2005;36:1019-27
    • (2005) J Pharm Biomed Anal , vol.36 , pp. 1019-1027
    • Calabro, M.L.1    Tommasini, S.2    Donato, P.3
  • 20
    • 61349095957 scopus 로고    scopus 로고
    • Development of an oral rutin nanocrystal formulation
    • Mauludin R, Müller RH, Keck CM. Development of an oral rutin nanocrystal formulation. Int J Pharm 2009;370:202-9
    • (2009) Int J Pharm , vol.370 , pp. 202-209
    • Mauludin, R.1    Müller, R.H.2    Keck, C.M.3
  • 21
    • 0033865338 scopus 로고    scopus 로고
    • Naturally occurring polyphenolic antioxidants modulate IgE-mediated mast cell activation
    • Chen S, Gong J, Liu F, et al. Naturally occurring polyphenolic antioxidants modulate IgE-mediated mast cell activation. Immunology 2000;100:471-80
    • (2000) Immunology , vol.100 , pp. 471-480
    • Chen, S.1    Gong, J.2    Liu, F.3
  • 22
    • 0029785036 scopus 로고    scopus 로고
    • Leg oedema protection from a buckwheat herb tea in patients with chronic venous insufficiency: A single-centre, randomised, double-blind, placebo-controlled clinical trial
    • Ihme N, Kiesewetter H, Jung F, et al. Leg oedema protection from a buckwheat herb tea in patients with chronic venous insufficiency: A single-centre, randomised, double-blind, placebo-controlled clinical trial. Eur J Clin Pharmacol 1996;50:443-7
    • (1996) Eur J Clin Pharmacol , vol.50 , pp. 443-447
    • Ihme, N.1    Kiesewetter, H.2    Jung, F.3
  • 23
    • 0025885064 scopus 로고
    • Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia
    • Deschner EE, Ruperto J, Wong G, et al. Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia. Carcinogenesis 1991;12:1193-6
    • (1991) Carcinogenesis , vol.12 , pp. 1193-1196
    • Deschner, E.E.1    Ruperto, J.2    Wong, G.3
  • 24
    • 0024839118 scopus 로고
    • Influence of flavonoids on combined experimental infections with EMC virus and Staphylococcus aureus in mice
    • Panasiak W, Wleklik M, Oraczewska A, et al. Influence of flavonoids on combined experimental infections with EMC virus and Staphylococcus aureus in mice. Acta Microbiol Pol 1989;38:185-8
    • (1989) Acta Microbiol Pol , vol.38 , pp. 185-188
    • Panasiak, W.1    Wleklik, M.2    Oraczewska, A.3
  • 25
    • 0036123569 scopus 로고    scopus 로고
    • Effect of rutin and tannic acid supplements on cholesterol metabolism in rats
    • Park SY, Bok SH, Jeon SM, et al. Effect of rutin and tannic acid supplements on cholesterol metabolism in rats. Nutr Res 2002;22:283-95
    • (2002) Nutr Res , vol.22 , pp. 283-295
    • Park, S.Y.1    Bok, S.H.2    Jeon, S.M.3
  • 26
    • 0008345428 scopus 로고    scopus 로고
    • Protective effect of rutin, a flavonol glycoside, on the carcinogen-induced DNA damage and repair enzymes in rats
    • Webster RP, Gawde MD, Bhattacharya RK. Protective effect of rutin, a flavonol glycoside, on the carcinogen-induced DNA damage and repair enzymes in rats. Cancer Lett 1996;109:185-91
    • (1996) Cancer Lett , vol.109 , pp. 185-191
    • Webster, R.P.1    Gawde, M.D.2    Bhattacharya, R.K.3
  • 27
    • 77951229157 scopus 로고    scopus 로고
    • Mahmoud AM antihyperglycemic, antihyperlipidemic and antioxidant effects and the probable mechanisms of action of ruta graveolens infusion and rutin in nicotinamide-Streptozotocin-induced diabetic rats
    • Ahmed OM, Moneim AA, Yazid A, et al. Mahmoud AM. Antihyperglycemic, antihyperlipidemic and antioxidant effects and the probable mechanisms of action of ruta graveolens infusion and rutin in nicotinamide-Streptozotocin-induced diabetic rats. Diabetologia Croatica 2010;39:15-35
    • (2010) Diabetologia Croatica , vol.39 , pp. 15-35
    • Ahmed, O.M.1    Moneim, A.A.2    Yazid, A.3
  • 28
    • 0022517744 scopus 로고
    • Inhibition of mitochondrial respiration and production of toxic oxygen radicals by flavonoids. A structure-activity study
    • Hodnick WF, Kung FS, Roettger WJ, et al. Inhibition of mitochondrial respiration and production of toxic oxygen radicals by flavonoids. A structure-activity study. Biochem Pharmacol 1986;35:2345-57
    • (1986) Biochem Pharmacol , vol.35 , pp. 2345-2357
    • Hodnick, W.F.1    Kung, F.S.2    Roettger, W.J.3
  • 29
    • 0033855277 scopus 로고    scopus 로고
    • Improvement of solubility and oral bioavailability of rutin by complexation with 2-hydroxypropyl-beta- cyclodextrin
    • Miyake K, Arima H, Hirayama F, et al. Improvement of solubility and oral bioavailability of rutin by complexation with 2-hydroxypropyl-beta- cyclodextrin. Pharm Dev Technol 2000;5:399-407
    • (2000) Pharm Dev Technol , vol.5 , pp. 399-407
    • Miyake, K.1    Arima, H.2    Hirayama, F.3
  • 30
    • 0036900252 scopus 로고    scopus 로고
    • Antimicrobial and antiviral activities of polyphenolics from cocos nucifera linn palmae) husk fiber extract
    • Esquenazi D, Wigg MD, Miranda MFS, et al. Antimicrobial and antiviral activities of polyphenolics from Cocos nucifera Linn. (Palmae) husk fiber extract. Res Microbio 2002;153:647-52
    • (2002) Res Microbio , vol.153 , pp. 647-652
    • Esquenazi, D.1    Wigg, M.D.2    Miranda, M.F.S.3
  • 32
    • 77956174157 scopus 로고    scopus 로고
    • Antibacterial, antifungal, and antiviral activities of some flavonoids
    • Orhan DD, Ozcelik B, Ozgen S, et al. Antibacterial, antifungal, and antiviral activities of some flavonoids. Microbio Res 2010;165:496-504
    • (2010) Microbio Res , vol.165 , pp. 496-504
    • Orhan, D.D.1    Ozcelik, B.2    Ozgen, S.3
  • 33
    • 83455258068 scopus 로고    scopus 로고
    • Antifungal activity of five species of polygala Brazilian
    • Johann S, Mendes BG, Missau FC, et al. Antifungal activity of five species of polygala Brazilian. J Microbial 2011;42:1065-75
    • (2011) J Microbial , vol.42 , pp. 1065-1075
    • Johann, S.1    Mendes, B.G.2    Missau, F.C.3
  • 34
    • 0036560710 scopus 로고    scopus 로고
    • Rutin enhanced antibacterial activities of flavonoids against Bacillus cereus and Salmonella enteriditis
    • Arima H, Ashida H, Danno GI. Rutin enhanced antibacterial activities of flavonoids against Bacillus cereus and Salmonella enteriditis. Biosci Biotechnol Biochem 2002;66:1009-14
    • (2002) Biosci Biotechnol Biochem , vol.66 , pp. 1009-1014
    • Arima, H.1    Ashida, H.2    Danno, G.I.3
  • 35
    • 0030364314 scopus 로고    scopus 로고
    • Candida albicans arthritis one year after successful treatment of fungemia in a healthy infant
    • Swanson H, Hughes PA, Messer SA, et al. Candida albicans arthritis one year after successful treatment of fungemia in a healthy infant. J Pediatr 1996;129:688-94
    • (1996) J Pediatr , vol.129 , pp. 688-694
    • Swanson, H.1    Hughes, P.A.2    Messer, S.A.3
  • 36
  • 37
    • 0019723683 scopus 로고
    • Candida albicans arthritis in a healthy adult
    • Arnold HJ, Dini A, Jonas G, et al. Candida albicans arthritis in a healthy adult. South Med J 1981;74:84-5
    • (1981) South Med J , vol.74 , pp. 84-85
    • Arnold, H.J.1    Dini, A.2    Jonas, G.3
  • 38
    • 58249128687 scopus 로고    scopus 로고
    • Rutin has therapeutic effect on septic arthritis caused by Candida albicans
    • Yongmoon H. Rutin has therapeutic effect on septic arthritis caused by Candida albicans. Int Immunopharmacol 2009;9:207-11
    • (2009) Int Immunopharmacol , vol.9 , pp. 207-211
    • Yongmoon, H.1
  • 39
    • 0033865338 scopus 로고    scopus 로고
    • Naturally occurring polyphenolic antioxidants modulate IgE-mediated mast cell activation
    • Chen SS, Gong J, Liu FT, et al. Naturally occurring polyphenolic antioxidants modulate IgE-mediated mast cell activation. Immunology 2000;100:471-80
    • (2000) Immunology , vol.100 , pp. 471-480
    • Chen, S.S.1    Gong, J.2    Liu, F.T.3
  • 40
    • 77953474824 scopus 로고    scopus 로고
    • Plant polyphenols as dietary antioxidants in human health and disease
    • Pandey KB, Rizvi SI. Plant polyphenols as dietary antioxidants in human health and disease. Oxid Med Cell Longev 2009;2:270-8
    • (2009) Oxid Med Cell Longev , vol.2 , pp. 270-278
    • Pandey, K.B.1    Rizvi, S.I.2
  • 42
    • 21144460399 scopus 로고
    • The flavonoids: New perspectives in biological activities and therapeutics
    • Bombardelli E, Morazzoni P. The flavonoids: New perspectives in biological activities and therapeutics. Chim Oggi 1993;11:25-8
    • (1993) Chim Oggi , vol.11 , pp. 25-28
    • Bombardelli, E.1    Morazzoni, P.2
  • 43
    • 40649109304 scopus 로고    scopus 로고
    • In vitro antioxidant properties of rutin
    • Yang J, Guo J, Yuan J. In vitro antioxidant properties of rutin. LWT 2008;41:1060-6
    • (2008) LWT , vol.41 , pp. 1060-1066
    • Yang, J.1    Guo, J.2    Yuan, J.3
  • 44
    • 33750042821 scopus 로고    scopus 로고
    • Rutin improves the antioxidant status in streptozotocin-induced diabetic rat tissues
    • Stanely- Mainzen Prince P.
    • Kamalakkannan N, Stanely- Mainzen Prince P. Rutin improves the antioxidant status in streptozotocin-induced diabetic rat tissues. Mol Cell Biochem 2006;293:211-19
    • (2006) Mol Cell Biochem , vol.293 , pp. 211-219
    • Kamalakkannan, N.1
  • 45
    • 84864953989 scopus 로고    scopus 로고
    • The protective effect of rutin against Ischemia/reperfusion-associated Hemodynamic alteration through antioxidant activity
    • Bhandary B, Piao CS, Kim DS, et al. The protective effect of rutin against Ischemia/reperfusion-associated Hemodynamic alteration through antioxidant activity. Arch Pharm Res 2012;35:1091-7
    • (2012) Arch Pharm Res , vol.35 , pp. 1091-1097
    • Bhandary, B.1    Piao, C.S.2    Kim, D.S.3
  • 46
    • 48649095089 scopus 로고    scopus 로고
    • Cancer chemoprevention and chemotherapy: Dietary polyphenols and signaling pathways
    • Ramos S. Cancer chemoprevention and chemotherapy: Dietary polyphenols and signaling pathways. Mol Nutr Food Res 2008;52:507-26
    • (2008) Mol Nutr Food Res , vol.52 , pp. 507-526
    • Ramos, S.1
  • 47
  • 48
    • 33748927815 scopus 로고    scopus 로고
    • Chemopreventive actions of polyphenolic compounds in cancer
    • Soobrattee MA, Bahorun T, Aruoma OI. Chemopreventive actions of polyphenolic compounds in cancer. Biofactors 2006;27:19-35
    • (2006) Biofactors , vol.27 , pp. 19-35
    • Soobrattee, M.A.1    Bahorun, T.2    Aruoma, O.I.3
  • 49
    • 0031040741 scopus 로고    scopus 로고
    • Effects of quercetin and/or restraint stress on formation of aberrant crypt foci induced by azoxymethane in rat colons
    • Matsukawa Y, Nishino H, Okuyama Y, et al. Effects of quercetin and/or restraint stress on formation of aberrant crypt foci induced by azoxymethane in rat colons. Oncology 1997;54:118-21
    • (1997) Oncology , vol.54 , pp. 118-121
    • Matsukawa, Y.1    Nishino, H.2    Okuyama, Y.3
  • 50
    • 73849096161 scopus 로고    scopus 로고
    • Rutin inhibits hydrogen peroxide-induced apoptosis through regulating reactive oxygen species mediated mitochondrial dysfunction pathway in human umbilical vein endothelial cells
    • Gong G, Qin Y, Huang W, et al. Rutin inhibits hydrogen peroxide-induced apoptosis through regulating reactive oxygen species mediated mitochondrial dysfunction pathway in human umbilical vein endothelial cells. Eur J Pharmacol 2009;628:27-35
    • (2009) Eur J Pharmacol , vol.628 , pp. 27-35
    • Gong, G.1    Qin, Y.2    Huang, W.3
  • 51
    • 84863561063 scopus 로고    scopus 로고
    • Rutin inhibits human leukemia tumor growth in a murine xenograft model in vivo
    • Yang JS, Jing-Pin L, Jen-Jyh L, et al. Rutin inhibits human leukemia tumor growth in a murine xenograft model in vivo. Inc Environ Toxicol 2011;27:480-4
    • (2011) Inc Environ Toxicol , vol.27 , pp. 480-484
    • Yang, J.S.1    Jing-Pin, L.2    Jen-Jyh, L.3
  • 52
    • 84894888799 scopus 로고    scopus 로고
    • Anticancer effect of rutin isolated from the methanolic extract of Triticum aestivum straw in mice
    • Ali H, Dixit S. Anticancer effect of rutin isolated from the methanolic extract of Triticum aestivum straw in mice. HOPE 2012;7:1-14
    • (2012) HOPE , vol.7 , pp. 1-14
    • Ali, H.1    Dixit, S.2
  • 53
    • 79952641157 scopus 로고    scopus 로고
    • Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines
    • Ara-ujo JR, Gonçalves P, Martel F. Chemopreventive effect of dietary polyphenols in colorectal cancer cell lines. Nut Res 2011;31:77-87
    • (2011) Nut Res , vol.31 , pp. 77-87
    • Ara-ujo, J.R.1    Gonçalves, P.2    Martel, F.3
  • 54
    • 0025885064 scopus 로고
    • Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia
    • Deschner EE, Ruperto J, Wong G, et al. Quercetin and rutin as inhibitors of azoxymethanol-induced colonic neoplasia. Carcinogenesis 1991;12:1193-6
    • (1991) Carcinogenesis , vol.12 , pp. 1193-1196
    • Deschner, E.E.1    Ruperto, J.2    Wong, G.3
  • 55
    • 0033071142 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase/lipoxygenase from human platelets by polyhydroxylated/methoxylated flavonoids isolated from medicinal plants
    • You KM, Jong HG, Kim HP. Inhibition of cyclooxygenase/lipoxygenase from human platelets by polyhydroxylated/methoxylated flavonoids isolated from medicinal plants. Arch Pharm Res 1999;22:18-24
    • (1999) Arch Pharm Res , vol.22 , pp. 18-24
    • You, K.M.1    Jong, H.G.2    Kim, H.P.3
  • 56
    • 0028933897 scopus 로고
    • Phosphatidylinositol 3-kinase inhibitors and their effects on cell signaling pathways
    • Vlahos CJ. Phosphatidylinositol 3-kinase inhibitors and their effects on cell signaling pathways. Drugs Future 1995;20:165-71
    • (1995) Drugs Future , vol.20 , pp. 165-171
    • Vlahos, C.J.1
  • 57
    • 0030612780 scopus 로고    scopus 로고
    • Flavonoids as phospholipase A2 inhibitors: Importance of their structure for selective inhibition of group II phospholipase A2
    • Lindahl M, Tagesson C. Flavonoids as phospholipase A2 inhibitors: Importance of their structure for selective inhibition of group II phospholipase A2. Inflammation 1997;21:347-56
    • (1997) Inflammation , vol.21 , pp. 347-356
    • Lindahl, M.1    Tagesson, C.2
  • 58
    • 0037347906 scopus 로고    scopus 로고
    • Anti-inflammatory effect of rutin on rat paw oedema, and on neutrophils chemotaxis and degranulation
    • Laid S, Hamama B, Chafia T, et al. Anti-inflammatory effect of rutin on rat paw oedema, and on neutrophils chemotaxis and degranulation. Exp Toxic Pathol 2003;54:313-18
    • (2003) Exp Toxic Pathol , vol.54 , pp. 313-318
    • Laid, S.1    Hamama, B.2    Chafia, T.3
  • 59
    • 84864076531 scopus 로고    scopus 로고
    • Barrier protective effects of rutin in LPS-induced inflammation in vitro and in vivo
    • Lee W, Ku SK, Bae JS. Barrier protective effects of rutin in LPS-induced inflammation in vitro and in vivo. Food Chem Tox 2012;50:3048-55
    • (2012) Food Chem Tox , vol.50 , pp. 3048-3055
    • Lee, W.1    Ku, S.K.2    Bae, J.S.3
  • 60
    • 79960843843 scopus 로고    scopus 로고
    • Rutin attenuates cisplatin induced renal inflammation and apoptosis by reducing NFkB, TNF-a and caspase-3 expression in wistar rats
    • Arjumand W, Seth A, Sultana S. Rutin attenuates cisplatin induced renal inflammation and apoptosis by reducing NFkB, TNF-a and caspase-3 expression in wistar rats. Food Chem Toxi 2011;49:2013-21
    • (2011) Food Chem Toxi , vol.49 , pp. 2013-2021
    • Arjumand, W.1    Seth, A.2    Sultana, S.3
  • 61
    • 33846938755 scopus 로고    scopus 로고
    • Rutin-induced endothelium-dependent vasorelaxation in rat aortic Rings and the underlying mechanism
    • Xia ML, Zhou XM, Yao H, et al. Rutin-induced endothelium-dependent vasorelaxation in rat aortic Rings and the underlying mechanism. Conf Proc IEEE Eng Med Biol Soc 2005;6:5595-7
    • (2005) Conf Proc IEEE Eng Med Biol Soc , vol.6 , pp. 5595-5597
    • Xia, M.L.1    Zhou, X.M.2    Yao, H.3
  • 62
    • 79956206256 scopus 로고    scopus 로고
    • Vasorelaxant and hypotensive effects of the extract and the isolated flavonoid rutin obtained from polygala paniculata L
    • Lapa FR, Soares KC, Rattmann YD, et al. Vasorelaxant and hypotensive effects of the extract and the isolated flavonoid rutin obtained from polygala paniculata L. J Pharm Pharmacol 2011;63:875-81
    • (2011) J Pharm Pharmacol , vol.63 , pp. 875-881
    • Lapa, F.R.1    Soares, K.C.2    Rattmann, Y.D.3
  • 63
    • 84869753385 scopus 로고    scopus 로고
    • Inhibition of angiotensin-converting enzyme activity by flavonoids: Structure-activity relationship studies
    • Guerrero L, Castillo J, Quinones M, et al. Inhibition of angiotensin-converting enzyme activity by flavonoids: Structure-activity relationship studies. Plos One 2012;7:1-11
    • (2012) Plos One , vol.7 , pp. 1-11
    • Guerrero, L.1    Castillo, J.2    Quinones, M.3
  • 64
    • 79952150907 scopus 로고    scopus 로고
    • Antihypertensive and other beneficial health effects of rutin supplementation in diabetic patients
    • Sattanathan K, Dhanapal CK, Manavalan R. Antihypertensive and other beneficial health effects of rutin supplementation in diabetic patients. Res J Pharm Bio Chem Sci 2011;2:843-9
    • (2011) Res J Pharm Bio Chem Sci , vol.2 , pp. 843-849
    • Sattanathan, K.1    Dhanapal, C.K.2    Manavalan, R.3
  • 65
    • 0026687429 scopus 로고
    • Effect of dietary fats on some membrane bound enzyme activities, membrane lipid composition and fatty acid profiles of rat heart sarcolemma
    • Vajreswari W, Narayanareddy K. Effect of dietary fats on some membrane bound enzyme activities, membrane lipid composition and fatty acid profiles of rat heart sarcolemma. Lipids 1992;27:339-43
    • (1992) Lipids , vol.27 , pp. 339-343
    • Vajreswari, W.1    Narayanareddy, K.2
  • 66
    • 34147142926 scopus 로고    scopus 로고
    • Preventive effect of rutin on lipids, lipoproteins, and ATPases in normal and isoproterenol-induced myocardial infarction in rats
    • Stanely P, Prince M, Karthick M. Preventive effect of rutin on lipids, lipoproteins, and ATPases in normal and isoproterenol-induced myocardial infarction in rats. J Biochem Mol Toxicol 2007;21:1-6
    • (2007) J Biochem Mol Toxicol , vol.21 , pp. 1-6
    • Stanely, P.1    Prince, M.2    Karthick, M.3
  • 67
    • 77956344706 scopus 로고    scopus 로고
    • Protective effects of rutin on mitochondrial damage in isoproterenol-induced cardiotoxic rats: An in vivo and in vitro study
    • Punithavathi VR, Shanmugapriya K, Stanely -Mainzen PP. Protective effects of rutin on mitochondrial damage in isoproterenol-induced cardiotoxic rats: An in vivo and in vitro study. Cardiovasc Toxicol 2010;10:181-9
    • (2010) Cardiovasc Toxicol , vol.10 , pp. 181-189
    • Punithavathi, V.R.1    Shanmugapriya, K.2    Stanely-Mainzen, P.P.3
  • 69
    • 0022384509 scopus 로고
    • Effects of flavonoids on insulin secretion and Ca +2 handling in rat islets of Langerhans
    • Hii CST, Howell SL. Effects of flavonoids on insulin secretion and Ca +2 handling in rat islets of Langerhans. J Endocrinol 1985;107:1-8
    • (1985) J Endocrinol , vol.107 , pp. 1-8
    • Hii, C.S.T.1    Howell, S.L.2
  • 70
    • 33645892889 scopus 로고    scopus 로고
    • Effect of citrus flavonoids on lipid metabolism and glucose-regulating enzyme mRNA levels in type-2 diabetic mice
    • Lee MK, Park YB, Kang MA, et al. Effect of citrus flavonoids on lipid metabolism and glucose-regulating enzyme mRNA levels in type-2 diabetic mice. Int J Biochem Cell Biol 2006;38:1134-45
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 1134-1145
    • Lee, M.K.1    Park, Y.B.2    Kang, M.A.3
  • 71
    • 13544252637 scopus 로고    scopus 로고
    • Upregulation of GLUT-4 and PPARg by an isoflavone from Pterocarpus marsupium on L6 myotubes: A possible mechanism of action
    • Anandharajan R, Pathmanathan K, Shankernarayanan NP, et al. Upregulation of GLUT-4 and PPARg by an isoflavone from Pterocarpus marsupium on L6 myotubes: A possible mechanism of action. J Ethnopharmacol 2005;97:253-60
    • (2005) J Ethnopharmacol , vol.97 , pp. 253-260
    • Anandharajan, R.1    Pathmanathan, K.2    Shankernarayanan, N.P.3
  • 72
    • 77951229157 scopus 로고    scopus 로고
    • Antihyperglycemic, antihyperlipidemic and antioxidant effects and the probable mechanisms of action of ruta graveolens infusion and rutin in nicotinamidestreptozotocin-induced diabetic rat
    • Ahmed OM, Moneim AA, Yazid IA, et al. Antihyperglycemic, antihyperlipidemic and antioxidant effects and the probable mechanisms of action of ruta graveolens infusion and rutin in nicotinamidestreptozotocin-induced diabetic rat. Diabetol Croat 2010;39:15-35
    • (2010) Diabetol Croat , vol.39 , pp. 15-35
    • Ahmed, O.M.1    Moneim, A.A.2    Yazid, I.A.3
  • 73
    • 33645103657 scopus 로고    scopus 로고
    • Antihyperglycaemic and antioxidant effect of rutin, a polyphenolic flavonoid, in streptozotocin-induced diabetic wistar rats
    • Kamalakkannan N, Stanely-Mainzen PP. Antihyperglycaemic and antioxidant effect of rutin, a polyphenolic flavonoid, in streptozotocin-induced diabetic wistar rats. Basic Clin Pharmacol Toxicol 2006;98:97-103
    • (2006) Basic Clin Pharmacol Toxicol , vol.98 , pp. 97-103
    • Kamalakkannan, N.1    Stanely-Mainzen, P.P.2
  • 74
    • 2442571121 scopus 로고    scopus 로고
    • Autoimmune disorders and extra intestinal manifestations in first-degree familial and sporadic inflammatory bowel disease: A case-control study
    • Ricart E, Panaccione R, Loftus EV, et al. Autoimmune disorders and extra intestinal manifestations in first-degree familial and sporadic inflammatory bowel disease: A case-control study. Inflamm Bowel Dis 2004;10:207-14
    • (2004) Inflamm Bowel Dis , vol.10 , pp. 207-214
    • Ricart, E.1    Panaccione, R.2    Loftus, E.V.3
  • 75
    • 0035999066 scopus 로고    scopus 로고
    • Flavonoids exert diverse inhibitory effects on the activation of NF-kappaB
    • Muraoka K, Shimizu K, Sun X, et al. Flavonoids exert diverse inhibitory effects on the activation of NF-kappaB. Transplant Proc 2002;34:1335-40
    • (2002) Transplant Proc , vol.34 , pp. 1335-1340
    • Muraoka, K.1    Shimizu, K.2    Sun, X.3
  • 76
    • 84655163812 scopus 로고    scopus 로고
    • Coated chitosan pellets containing rutin intended for the treatment of inflammatory bowel disease: In vitro characteristics and in vivo evaluation
    • Rabiskova M, Bautzova T, Gajdziok J, et al. Coated chitosan pellets containing rutin intended for the treatment of inflammatory bowel disease: In vitro characteristics and in vivo evaluation. Int J Pharm 2012;422:151-9
    • (2012) Int J Pharm , vol.422 , pp. 151-159
    • Rabiskova, M.1    Bautzova, T.2    Gajdziok, J.3
  • 77
    • 24044511500 scopus 로고    scopus 로고
    • Metabolic and pharmacological properties of rutin, a dietary quercetin glycoside, for treatment of inflammatory bowel disease
    • Kim H, Kong H, Choi B, et al. Metabolic and pharmacological properties of rutin, a dietary quercetin glycoside, for treatment of inflammatory bowel disease. Pharm Res 2005;22:1499-509
    • (2005) Pharm Res , vol.22 , pp. 1499-1509
    • Kim, H.1    Kong, H.2    Choi, B.3
  • 78
    • 50549085408 scopus 로고    scopus 로고
    • Neuroinflammation and oxidation/nitration of alpha synuclein linked to dopaminergic neurodegeneration
    • Gao HM, Kotzbauer PT, Uryu K, et al. Neuroinflammation and oxidation/nitration of alpha synuclein linked to dopaminergic neurodegeneration. J Neurosci 2008;28:7687-98
    • (2008) J Neurosci , vol.28 , pp. 7687-7698
    • Gao, H.M.1    Kotzbauer, P.T.2    Uryu, K.3
  • 79
    • 69449089391 scopus 로고    scopus 로고
    • Rutin protects the neural damage induced by transient focal ischemia in rats
    • Khan MM, Ahmad A, Ishrat T, et al. Rutin protects the neural damage induced by transient focal ischemia in rats. Brain Res 2009;1292:123-35
    • (2009) Brain Res , vol.1292 , pp. 123-135
    • Khan, M.M.1    Ahmad, A.2    Ishrat, T.3
  • 80
    • 84861456441 scopus 로고    scopus 로고
    • Rutin protects dopaminergic neurons from oxidative stress in an animal model of parkinson's disease
    • Moshahid KM, Raza SS, Javed H, et al. Rutin Protects Dopaminergic Neurons from Oxidative Stress in an Animal Model of Parkinson's Disease. Neurotox Res 2012;22:1-15
    • (2012) Neurotox Res , vol.22 , pp. 1-15
    • Moshahid, K.M.1    Raza, S.S.2    Javed, H.3
  • 81
    • 84875217532 scopus 로고    scopus 로고
    • Therapeutic potential of treatment with the flavonoid rutin after cortical focal ischemia in rats
    • Rodrigues AMG, Marcilio F, Muzitano M, et al. Therapeutic potential of treatment with the flavonoid rutin after cortical focal ischemia in rats. Brain Res 2013;1503:53-61
    • (2013) Brain Res , vol.1503 , pp. 53-61
    • Rodrigues, A.M.G.1    Marcilio, F.2    Muzitano, M.3
  • 82
    • 34548613764 scopus 로고    scopus 로고
    • Protective effect of rutin, a polyphenolic flavonoid against haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes
    • Bishnoi M, Chopra K, Kulkarni SK. Protective effect of rutin, a polyphenolic flavonoid against haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes. Fundam Clin Pharmacol 2007;21:521-9
    • (2007) Fundam Clin Pharmacol , vol.21 , pp. 521-529
    • Bishnoi, M.1    Chopra, K.2    Kulkarni, S.K.3
  • 83
    • 78149273255 scopus 로고    scopus 로고
    • Quercetin and rutin prevent scopolamine-induced memory impairment in zebrafish
    • Richetti SK, Blank M, Capiotti KM, et al. Quercetin and rutin prevent scopolamine-induced memory impairment in zebrafish. Behav Brain Res 2011;217:10-15
    • (2011) Behav Brain Res , vol.217 , pp. 10-15
    • Richetti, S.K.1    Blank, M.2    Capiotti, K.M.3
  • 84
    • 84861200675 scopus 로고    scopus 로고
    • Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type
    • Javed H, Khan MM, Ahmad A, et al. Rutin prevents cognitive impairments by ameliorating oxidative stress and neuroinflammation in rat model of sporadic dementia of Alzheimer type. Neuroscience 2012;210:340-52
    • (2012) Neuroscience , vol.210 , pp. 340-352
    • Javed, H.1    Khan, M.M.2    Ahmad, A.3
  • 85
    • 84861519208 scopus 로고    scopus 로고
    • Hydrogels containing rutin intended for cutaneous administration: Efficacy in wound healing in rats
    • Almeida JS, Benvegn-u DM, Boufleur N, et al. Hydrogels containing rutin intended for cutaneous administration: Efficacy in wound healing in rats. Drug Dev Indus Pharm 2012;38:792-9
    • (2012) Drug Dev Indus Pharm , vol.38 , pp. 792-799
    • Almeida, J.S.1    Benvegn-u, D.M.2    Boufleur, N.3
  • 86
    • 80051485391 scopus 로고    scopus 로고
    • Situ forming and rutin-releasing chitosan hydrogels as injectable dressings for dermal wound healing
    • Tran NQ, Joung YK, Lih E, et al. In situ forming and rutin-releasing chitosan hydrogels as injectable dressings for dermal wound healing. Biomacromolecules 2011;12:2872-80
    • (2011) Biomacromolecules , vol.12 , pp. 2872-2880
    • Tran, N.Q.1    Joung, Y.K.2    Lih, E.3
  • 87
    • 0033759897 scopus 로고    scopus 로고
    • Bioavailability and efficiency of rutin as an antioxidant: A human supplementation study
    • Boyle SP, Dobson VL, Duthie SJ, et al. Bioavailability and efficiency of rutin as an antioxidant: A human supplementation study. Eur J Clin Nut 2000;54:774-84
    • (2000) Eur J Clin Nut , vol.54 , pp. 774-784
    • Boyle, S.P.1    Dobson, V.L.2    Duthie, S.J.3
  • 89
    • 28044467747 scopus 로고    scopus 로고
    • Bioavailability and metabolic pharmacokinetics of rutin and quercetin in rats
    • Yang C, Hsiu S, Wen K, et al. Bioavailability and metabolic pharmacokinetics of rutin and quercetin in rats. J Food Drug Ana 2005;13:244-50
    • (2005) J Food Drug Ana , vol.13 , pp. 244-250
    • Yang, C.1    Hsiu, S.2    Wen, K.3
  • 90
    • 13844281685 scopus 로고    scopus 로고
    • Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies
    • Manach C, Williamson G, Morand C, et al. Bioavailability and bioefficacy of polyphenols in humans. I. Review of 97 bioavailability studies. Am J Clin Nutr 2005;81:230S-42S
    • (2005) Am J Clin Nutr
    • Manach, C.1    Williamson, G.2    Morand, C.3
  • 91
    • 84894893612 scopus 로고    scopus 로고
    • Pharmacokinetic study of rutin in normal and diabetic nephropathy rats
    • Xiao L, Daoquan T, Xiaoxing Y, et al. Pharmacokinetic study of rutin in normal and diabetic nephropathy rats. Acta Acad Med Xuzhou 2009;11:708-12
    • (2009) Acta Acad Med Xuzhou , vol.11 , pp. 708-712
    • Xiao, L.1    Daoquan, T.2    Xiaoxing, Y.3
  • 92
    • 0033759897 scopus 로고    scopus 로고
    • Bioavailability and efficiency of rutin as an antioxidant: A human supplementation study
    • Boyle SP, Dobson VL, Duthie SJ, et al. Bioavailability and efficiency of rutin as an antioxidant: A human supplementation study. Eur J Clin Nutr 2000;54:774-82
    • (2000) Eur J Clin Nutr , vol.54 , pp. 774-782
    • Boyle, S.P.1    Dobson, V.L.2    Duthie, S.J.3
  • 93
    • 0033661837 scopus 로고    scopus 로고
    • Pharmacokinetic of quercetin from quercetin aglycone and rutin in healthy volunteers
    • Erlund I, Kosonen T, Alfthan G, et al. Pharmacokinetic of quercetin from quercetin aglycone and rutin in healthy volunteers. Eur J Clin Pharmacol 2000;56:545-53
    • (2000) Eur J Clin Pharmacol , vol.56 , pp. 545-553
    • Erlund, I.1    Kosonen, T.2    Alfthan, G.3
  • 94
    • 75249100215 scopus 로고    scopus 로고
    • Lymphatic absorption of quercetin and rutin in rat and their pharmacokinetics in systemic plasma
    • Chen I, Tsai Y, Huang C, et al. Lymphatic absorption of quercetin and rutin in rat and their pharmacokinetics in systemic plasma. J. Agric Food Chem 2010;58:546-51
    • (2010) J. Agric Food Chem , vol.58 , pp. 546-551
    • Chen, I.1    Tsai, Y.2    Huang, C.3
  • 95
    • 0036001089 scopus 로고    scopus 로고
    • Fast- and slow-release tablets for oral administration of Flavonoids: Rutin and Quercetin
    • Lauro MR, Torre M.L, Maggi L, et al. Fast- and slow-release tablets for oral administration of Flavonoids: Rutin and Quercetin. Drug Dev Ind Pharm 2002;28:371-9
    • (2002) Drug Dev Ind Pharm , vol.28 , pp. 371-379
    • Lauro, M.R.1    Torre, M.L.2    Maggi, L.3
  • 96
    • 0029819323 scopus 로고    scopus 로고
    • Pharmaceutical applications of cyclodextrins. Drug solubilization and stabilization
    • Loftsson T, Brewster ME. Pharmaceutical applications of cyclodextrins. Drug solubilization and stabilization. J Pharm Sci 1996;85:1017-24
    • (1996) J Pharm Sci , vol.85 , pp. 1017-1024
    • Loftsson, T.1    Brewster, M.E.2
  • 97
    • 0033807215 scopus 로고    scopus 로고
    • 2-Hydroxypropyl- 13 b-cyclodextrin increases aqueous solubility and photostability of all-trans-retinoic acid
    • Lin HS, Chean CS, Nug YY, et al. 2-Hydroxypropyl- 13 b-cyclodextrin increases aqueous solubility and photostability of all-trans-retinoic acid. J Clin Pharm Ther 2000;25:265-9
    • (2000) J Clin Pharm Ther , vol.25 , pp. 265-269
    • Lin, H.S.1    Chean, C.S.2    Nug, Y.Y.3
  • 98
    • 34247499876 scopus 로고    scopus 로고
    • Preparation and characterization of quercetin and rutin cyclodextrin inclusion complexes
    • Sri KV, Kondaiah A, Ratna JV, et al. Preparation and characterization of quercetin and rutin cyclodextrin inclusion complexes. Drug Dev Ind Pharm 2007;33:245-53
    • (2007) Drug Dev Ind Pharm , vol.33 , pp. 245-253
    • Sri, K.V.1    Kondaiah, A.2    Ratna, J.V.3
  • 99
    • 84865489975 scopus 로고    scopus 로고
    • An investigation into the supramolecular structure, solubility, stability and antioxidant activity of rutin/cyclodextrin inclusion complex
    • Nguyen T, Liu B, Zhao J, et al. An investigation into the supramolecular structure, solubility, stability and antioxidant activity of rutin/cyclodextrin inclusion complex. Food Chem 2013;136:186-92
    • (2013) Food Chem , vol.136 , pp. 186-192
    • Nguyen, T.1    Liu, B.2    Zhao, J.3
  • 100
    • 25644448238 scopus 로고    scopus 로고
    • A review of the bioavailability and clinical efficacy of milk thistle phytosome: A silybin-phosphatidylcholine complex (Siliphos-)
    • Kidd PM, Head K. A review of the bioavailability and clinical efficacy of milk thistle phytosome: A silybin-phosphatidylcholine complex (Siliphos-). Altern Med Rev 2005;10:193-203
    • (2005) Altern Med Rev , vol.10 , pp. 193-203
    • Kidd, P.M.1    Head, K.2
  • 101
    • 0347889077 scopus 로고
    • Complex between phospholipids and vegetal derivatives of biological interest
    • Bombardelli E, Curri SB, Loggia RD, et al. Complex between phospholipids and vegetal derivatives of biological interest. Fitoterapia 1989;60:1-9
    • (1989) Fitoterapia , vol.60 , pp. 1-9
    • Bombardelli, E.1    Curri, S.B.2    Loggia, R.D.3
  • 102
    • 84878020302 scopus 로고    scopus 로고
    • Physicochemical characterization and determination of free radical scavenging activity of rutin-phospholipid complex
    • Jain S, Dhanotiya C, Malviya N. Physicochemical characterization and determination of free radical scavenging activity of rutin-phospholipid complex. Int J Pharm Sci Res 2012;3:909-13
    • (2012) Int J Pharm Sci Res , vol.3 , pp. 909-913
    • Jain, S.1    Dhanotiya, C.2    Malviya, N.3
  • 103
    • 84860517068 scopus 로고    scopus 로고
    • Rutin-phospholipid complex: An innovative technique in novel drug delivery system-NDDS
    • Singh D, Rawat MS, Semalty A, et al. Rutin-phospholipid complex: An innovative technique in novel drug delivery system-NDDS. Curr Drug Deliv 2012;9:305-14
    • (2012) Curr Drug Deliv , vol.9 , pp. 305-314
    • Singh, D.1    Rawat, M.S.2    Semalty, A.3
  • 104
    • 78650068904 scopus 로고    scopus 로고
    • Conundrum and therapeutic potential of curcumin in drug delivery
    • Kumar A, Ahuja A, Ali J, et al. Conundrum and therapeutic potential of curcumin in drug delivery. Critical Rev Thera Drug Carr Sys 2010;27:279-320
    • (2010) Critical Rev Thera Drug Carr Sys , vol.27 , pp. 279-320
    • Kumar, A.1    Ahuja, A.2    Ali, J.3
  • 105
    • 61349095957 scopus 로고    scopus 로고
    • Development of an oral rutin nanocrystal formulation
    • Mauludin R, Müller RH, Keck CM. Development of an oral rutin nanocrystal formulation. Int J Pharm 2009;370:202-9
    • (2009) Int J Pharm , vol.370 , pp. 202-209
    • Mauludin, R.1    Müller, R.H.2    Keck, C.M.3
  • 106
    • 77958485854 scopus 로고    scopus 로고
    • Nanostructured systems containing rutin: In vitro antioxidant activity and photostability studies
    • Almeida JS, Lima F, Ros S, et al. Nanostructured systems containing rutin: In vitro antioxidant activity and photostability studies. Nanoscale Res Lett 2010;5:1603-10
    • (2010) Nanoscale Res Lett , vol.5 , pp. 1603-1610
    • Almeida, J.S.1    Lima, F.2    Ros, S.3
  • 107
    • 84856792609 scopus 로고    scopus 로고
    • Formulation design and evalution of rutin loaded selfemulsifying drug delivery system (SEDDs) using edible oil
    • Kumar VP, Khan A. Formulation design and evalution of rutin loaded selfemulsifying drug delivery system (SEDDs) using edible oil. Asia J Pharm Clin Re 2012;5:76-8
    • (2012) Asia J Pharm Clin Re , vol.5 , pp. 76-78
    • Kumar, V.P.1    Khan, A.2
  • 108
    • 84894888551 scopus 로고    scopus 로고
    • Development of biocompatible nanoparticles for sustained topical delivery of Rutin
    • Banjare L, Ghillare N. Development of biocompatible nanoparticles for sustained topical delivery of Rutin. Int J Pharm Bio Arch 2012;3:326-32
    • (2012) Int J Pharm Bio Arch , vol.3 , pp. 326-332
    • Banjare, L.1    Ghillare, N.2
  • 109
    • 84873286344 scopus 로고    scopus 로고
    • Development of a novel vesicular system using a binary mixture of sorbitan monostearate and polyethylene glycol fatty acid esters for rectal delivery of rutin
    • Kamel R, Basha M, Abd El-Alim SH. Development of a novel vesicular system using a binary mixture of sorbitan monostearate and polyethylene glycol fatty acid esters for rectal delivery of rutin. Liposome Res 2013;23:28-36
    • (2013) Liposome Res , vol.23 , pp. 28-36
    • Kamel, R.1    Basha, M.2    Abd El-Alim, S.H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.