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Volumn 147, Issue , 2016, Pages 1-19

Oxidative stress: A major pathogenesis and potential therapeutic target of antioxidative agents in Parkinson's disease and Alzheimer's disease

Author keywords

Antioxidative agent; Mitochondria; NADPH oxidase; Neurodegenerative disease; Oxidative stress; Signaling pathway

Indexed keywords

ALPHA SYNUCLEIN; AMYLOID BETA PROTEIN; ANTIOXIDANT; DJ 1 PROTEIN; FREE RADICAL; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NEUROPROTECTIVE AGENT; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; TAU PROTEIN;

EID: 84996843203     PISSN: 03010082     EISSN: 18735118     Source Type: Journal    
DOI: 10.1016/j.pneurobio.2016.07.005     Document Type: Review
Times cited : (503)

References (236)
  • 1
    • 33845933757 scopus 로고    scopus 로고
    • Involvement of PI3 K/PKG/ERK1/2 signaling pathways in cortical neurons to trigger protection by co-treatment of acetyl-L-carnitine and α-lipoic acid against HNE-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease
    • Abdul, H.M., Butterfield, D.A., Involvement of PI3 K/PKG/ERK1/2 signaling pathways in cortical neurons to trigger protection by co-treatment of acetyl-L-carnitine and α-lipoic acid against HNE-mediated oxidative stress and neurotoxicity: implications for Alzheimer's disease. Free Radic. Biol. Med., 42, 2007, 371.
    • (2007) Free Radic. Biol. Med. , vol.42 , pp. 371
    • Abdul, H.M.1    Butterfield, D.A.2
  • 2
    • 84941331228 scopus 로고    scopus 로고
    • World Alzheimer Report 2015: The Global Impact of Dementia
    • Alzheimer's Disease Internationa London
    • Ali, G.-C., Guerchet, M., Wu, Y.-T., Prince, M., Prina, M., Wimo, A., World Alzheimer Report 2015: The Global Impact of Dementia., 2015, Alzheimer's Disease Internationa, London.
    • (2015)
    • Ali, G.-C.1    Guerchet, M.2    Wu, Y.-T.3    Prince, M.4    Prina, M.5    Wimo, A.6
  • 3
    • 0035811050 scopus 로고    scopus 로고
    • Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments
    • Alonso, A., Zaidi, T., Novak, M., Grundke-Iqbal, I., Iqbal, K., Hyperphosphorylation induces self-assembly of tau into tangles of paired helical filaments/straight filaments. Proc. Natl. Acad. Sci. U. S. A. 98 (2001), 6923–6928.
    • (2001) Proc. Natl. Acad. Sci. U. S. A. , vol.98 , pp. 6923-6928
    • Alonso, A.1    Zaidi, T.2    Novak, M.3    Grundke-Iqbal, I.4    Iqbal, K.5
  • 4
    • 84886600387 scopus 로고    scopus 로고
    • Therapeutics of Alzheimer's disease: past, present and future
    • Anand, R., Gill, K.D., Mahdi, A.A., Therapeutics of Alzheimer's disease: past, present and future. Neuropharmacology 76:Pt A (2014), 27–50.
    • (2014) Neuropharmacology , vol.76 , pp. 27-50
    • Anand, R.1    Gill, K.D.2    Mahdi, A.A.3
  • 8
    • 80053525105 scopus 로고    scopus 로고
    • Spatial patterns of beta-amyloid (Abeta) deposits in familial and sporadic Alzheimer's disease
    • Armstrong, R.A., Spatial patterns of beta-amyloid (Abeta) deposits in familial and sporadic Alzheimer's disease. Folia Neuropathol. 49 (2011), 153–161.
    • (2011) Folia Neuropathol. , vol.49 , pp. 153-161
    • Armstrong, R.A.1
  • 9
    • 84925830612 scopus 로고    scopus 로고
    • Laminar distribution of beta-amyloid (Abeta) peptide deposits in the frontal lobe in familial and sporadic Alzheimer's disease
    • Armstrong, R.A., Laminar distribution of beta-amyloid (Abeta) peptide deposits in the frontal lobe in familial and sporadic Alzheimer's disease. Folia Neuropathol. 53 (2015), 15–23.
    • (2015) Folia Neuropathol. , vol.53 , pp. 15-23
    • Armstrong, R.A.1
  • 14
    • 33846794822 scopus 로고    scopus 로고
    • The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology
    • Bedard, K., Krause, K.H., The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol. Rev. 87 (2007), 245–313.
    • (2007) Physiol. Rev. , vol.87 , pp. 245-313
    • Bedard, K.1    Krause, K.H.2
  • 15
    • 84862505183 scopus 로고    scopus 로고
    • Human SOD2 modification by dopamine quinones affects enzymatic activity by promoting its aggregation: possible implications for Parkinson's disease
    • Belluzzi, E., Bisaglia, M., Lazzarini, E., Tabares, L.C., Beltramini, M., Bubacco, L., Human SOD2 modification by dopamine quinones affects enzymatic activity by promoting its aggregation: possible implications for Parkinson's disease. PLoS One, 7, 2012, e38026.
    • (2012) PLoS One , vol.7 , pp. e38026
    • Belluzzi, E.1    Bisaglia, M.2    Lazzarini, E.3    Tabares, L.C.4    Beltramini, M.5    Bubacco, L.6
  • 16
  • 17
    • 33847378451 scopus 로고    scopus 로고
    • Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis
    • Bjelakovic, G., Nikolova, D., Gluud, L.L., Simonetti, R.G., Gluud, C., Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA 297 (2007), 842–857.
    • (2007) JAMA , vol.297 , pp. 842-857
    • Bjelakovic, G.1    Nikolova, D.2    Gluud, L.L.3    Simonetti, R.G.4    Gluud, C.5
  • 18
  • 19
    • 34548770783 scopus 로고    scopus 로고
    • LRRK2 low-penetrance mutations (Gly2019Ser) and risk alleles (Gly2385Arg)-linking familial and sporadic Parkinson's disease
    • Bonifati, V., LRRK2 low-penetrance mutations (Gly2019Ser) and risk alleles (Gly2385Arg)-linking familial and sporadic Parkinson's disease. Neurochem. Res. 32 (2007), 1700–1708.
    • (2007) Neurochem. Res. , vol.32 , pp. 1700-1708
    • Bonifati, V.1
  • 20
    • 75149148788 scopus 로고    scopus 로고
    • Why vitamin E therapy fails for treatment of Alzheimer's disease
    • Brewer, G.J., Why vitamin E therapy fails for treatment of Alzheimer's disease. J. Alzheimers Dis. 19 (2010), 27–30.
    • (2010) J. Alzheimers Dis. , vol.19 , pp. 27-30
    • Brewer, G.J.1
  • 22
    • 84947792074 scopus 로고    scopus 로고
    • Synthetic curcumin analogs as inhibitors of beta – amyloid peptide aggregation: potential therapeutic and diagnostic agents for alzheimer's disease
    • Bukhari, S.N., Jantan, I., Synthetic curcumin analogs as inhibitors of beta – amyloid peptide aggregation: potential therapeutic and diagnostic agents for alzheimer's disease. Mini Rev. Med. Chem. 15 (2015), 1110–1121.
    • (2015) Mini Rev. Med. Chem. , vol.15 , pp. 1110-1121
    • Bukhari, S.N.1    Jantan, I.2
  • 23
    • 84861470082 scopus 로고    scopus 로고
    • Methionine-35 of abeta(1–42): importance for oxidative stress in Alzheimer disease
    • Butterfield, D.A., Sultana, R., Methionine-35 of abeta(1–42): importance for oxidative stress in Alzheimer disease. J. Amino Acids, 2011, 2011, 198430.
    • (2011) J. Amino Acids , vol.2011 , pp. 198430
    • Butterfield, D.A.1    Sultana, R.2
  • 24
    • 84877072330 scopus 로고    scopus 로고
    • Amyloid beta-peptide (1–42)-induced oxidative stress in Alzheimer disease: importance in disease pathogenesis and progression
    • Butterfield, D.A., Swomley, A.M., Sultana, R., Amyloid beta-peptide (1–42)-induced oxidative stress in Alzheimer disease: importance in disease pathogenesis and progression. Antioxid. Redox Signal. 19 (2013), 823–835.
    • (2013) Antioxid. Redox Signal. , vol.19 , pp. 823-835
    • Butterfield, D.A.1    Swomley, A.M.2    Sultana, R.3
  • 25
    • 0028473764 scopus 로고
    • Initiating treatment for idiopathic parkinsonism
    • Calne, D.B., Initiating treatment for idiopathic parkinsonism. Neurology 44 (1994), S19–22.
    • (1994) Neurology , vol.44 , pp. S19-22
    • Calne, D.B.1
  • 27
    • 78549284583 scopus 로고    scopus 로고
    • Clinical aspects of melatonin intervention in Alzheimer's disease progression
    • Cardinali, D.P., Furio, A.M., Brusco, L.I., Clinical aspects of melatonin intervention in Alzheimer's disease progression. Curr. Neuropharmacol. 8 (2010), 218–227.
    • (2010) Curr. Neuropharmacol. , vol.8 , pp. 218-227
    • Cardinali, D.P.1    Furio, A.M.2    Brusco, L.I.3
  • 28
    • 84894441295 scopus 로고    scopus 로고
    • The P2X7 receptor antagonist Brilliant Blue G attenuates contralateral rotations in a rat model of Parkinsonism through a combined control of synaptotoxicity, neurotoxicity and gliosis
    • Carmo, M.R., Menezes, A.P., Nunes, A.C., Pliassova, A., Rolo, A.P., Palmeira, C.M., Cunha, R.A., Canas, P.M., Andrade, G.M., The P2X7 receptor antagonist Brilliant Blue G attenuates contralateral rotations in a rat model of Parkinsonism through a combined control of synaptotoxicity, neurotoxicity and gliosis. Neuropharmacology 81 (2014), 142–152.
    • (2014) Neuropharmacology , vol.81 , pp. 142-152
    • Carmo, M.R.1    Menezes, A.P.2    Nunes, A.C.3    Pliassova, A.4    Rolo, A.P.5    Palmeira, C.M.6    Cunha, R.A.7    Canas, P.M.8    Andrade, G.M.9
  • 29
    • 0029774196 scopus 로고    scopus 로고
    • The length of amyloid-beta in hereditary cerebral hemorrhage with amyloidosis: dutch type. Implications for the role of amyloid-beta 1–42 in Alzheimer's disease
    • Castano, E.M., Prelli, F., Soto, C., Beavis, R., Matsubara, E., Shoji, M., Frangione, B., The length of amyloid-beta in hereditary cerebral hemorrhage with amyloidosis: dutch type. Implications for the role of amyloid-beta 1–42 in Alzheimer's disease. J. Biol. Chem. 271 (1996), 32185–32191.
    • (1996) J. Biol. Chem. , vol.271 , pp. 32185-32191
    • Castano, E.M.1    Prelli, F.2    Soto, C.3    Beavis, R.4    Matsubara, E.5    Shoji, M.6    Frangione, B.7
  • 30
    • 84878664502 scopus 로고    scopus 로고
    • Systemic oxidative stress in older patients with mild cognitive impairment or late onset Alzheimer's disease
    • Cervellati, C., Cremonini, E., Bosi, C., Magon, S., Zurlo, A., Bergamini, C.M., Zuliani, G., Systemic oxidative stress in older patients with mild cognitive impairment or late onset Alzheimer's disease. Curr. Alzheimer Res. 10 (2013), 365–372.
    • (2013) Curr. Alzheimer Res. , vol.10 , pp. 365-372
    • Cervellati, C.1    Cremonini, E.2    Bosi, C.3    Magon, S.4    Zurlo, A.5    Bergamini, C.M.6    Zuliani, G.7
  • 32
    • 84872691988 scopus 로고    scopus 로고
    • Mutant LRRK2 elicits calcium imbalance and depletion of dendritic mitochondria in neurons
    • Cherra 3rd, S.J., Steer, E., Gusdon, A.M., Kiselyov, K., Chu, C.T., Mutant LRRK2 elicits calcium imbalance and depletion of dendritic mitochondria in neurons. Am. J. Pathol. 182 (2013), 474–484.
    • (2013) Am. J. Pathol. , vol.182 , pp. 474-484
    • Cherra 3rd, S.J.1    Steer, E.2    Gusdon, A.M.3    Kiselyov, K.4    Chu, C.T.5
  • 34
    • 84964478223 scopus 로고    scopus 로고
    • N-Adamantyl-4-methylthiazol-2-amine suppresses amyloid beta-induced neuronal oxidative damage in cortical neurons
    • Cho, C.H., Kim, E.A., Kim, J., Choi, S.Y., Yang, S.J., Cho, S.W., N-Adamantyl-4-methylthiazol-2-amine suppresses amyloid beta-induced neuronal oxidative damage in cortical neurons. Free Radic. Res., 2016, 1–35.
    • (2016) Free Radic. Res. , pp. 1-35
    • Cho, C.H.1    Kim, E.A.2    Kim, J.3    Choi, S.Y.4    Yang, S.J.5    Cho, S.W.6
  • 37
    • 0035834360 scopus 로고    scopus 로고
    • Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct
    • Conway, K.A., Rochet, J.C., Bieganski, R.M., Lansbury, P.T. Jr., Kinetic stabilization of the alpha-synuclein protofibril by a dopamine-alpha-synuclein adduct. Science 294 (2001), 1346–1349.
    • (2001) Science , vol.294 , pp. 1346-1349
    • Conway, K.A.1    Rochet, J.C.2    Bieganski, R.M.3    Lansbury, P.T.4
  • 39
    • 34047261260 scopus 로고    scopus 로고
    • ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
    • Cruz, C.M., Rinna, A., Forman, H.J., Ventura, A.L., Persechini, P.M., Ojcius, D.M., ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages. J. Biol. Chem. 282 (2007), 2871–2879.
    • (2007) J. Biol. Chem. , vol.282 , pp. 2871-2879
    • Cruz, C.M.1    Rinna, A.2    Forman, H.J.3    Ventura, A.L.4    Persechini, P.M.5    Ojcius, D.M.6
  • 40
    • 0030702123 scopus 로고    scopus 로고
    • Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery
    • Datta, S.R., Dudek, H., Tao, X., Masters, S., Fu, H., Gotoh, Y., Greenberg, M.E., Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery. Cell 91 (1997), 231–241.
    • (1997) Cell , vol.91 , pp. 231-241
    • Datta, S.R.1    Dudek, H.2    Tao, X.3    Masters, S.4    Fu, H.5    Gotoh, Y.6    Greenberg, M.E.7
  • 41
    • 77953424577 scopus 로고    scopus 로고
    • The role of parkin in familial and sporadic Parkinson's disease
    • Dawson, T.M., Dawson, V.L., The role of parkin in familial and sporadic Parkinson's disease. Mov. Disord. 25:Suppl 1 (2010), S32–S39.
    • (2010) Mov. Disord. , vol.25 , pp. S32-S39
    • Dawson, T.M.1    Dawson, V.L.2
  • 44
    • 84891645843 scopus 로고    scopus 로고
    • The role of oxidative stress in Parkinson's disease
    • Dias, V., Junn, E., Mouradian, M.M., The role of oxidative stress in Parkinson's disease. J. Parkinsons Dis. 3 (2013), 461–491.
    • (2013) J. Parkinsons Dis. , vol.3 , pp. 461-491
    • Dias, V.1    Junn, E.2    Mouradian, M.M.3
  • 46
    • 68849110235 scopus 로고    scopus 로고
    • Reduction of oxidative stress amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease
    • Dumont, M., Wille, E., Stack, C., Calingasan, N.Y., Beal, M.F., Lin, M.T., Reduction of oxidative stress amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease. FASEB J. 23 (2009), 2459–2466.
    • (2009) FASEB J. , vol.23 , pp. 2459-2466
    • Dumont, M.1    Wille, E.2    Stack, C.3    Calingasan, N.Y.4    Beal, M.F.5    Lin, M.T.6
  • 47
    • 33646922865 scopus 로고    scopus 로고
    • Reduction in mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice
    • Esposito, L., Raber, J., Kekonius, L., Yan, F., Yu, G.Q., Bien-Ly, N., Puolivali, J., Scearce-Levie, K., Masliah, E., Mucke, L., Reduction in mitochondrial superoxide dismutase modulates Alzheimer's disease-like pathology and accelerates the onset of behavioral changes in human amyloid precursor protein transgenic mice. J. Neurosci. 26 (2006), 5167–5179.
    • (2006) J. Neurosci. , vol.26 , pp. 5167-5179
    • Esposito, L.1    Raber, J.2    Kekonius, L.3    Yan, F.4    Yu, G.Q.5    Bien-Ly, N.6    Puolivali, J.7    Scearce-Levie, K.8    Masliah, E.9    Mucke, L.10
  • 48
    • 77953728876 scopus 로고    scopus 로고
    • Oxidative stress impairs learning and memory in apoE knockout mice
    • Evola, M., Hall, A., Wall, T., Young, A., Grammas, P., Oxidative stress impairs learning and memory in apoE knockout mice. Pharmacol. Biochem. Behav. 96 (2010), 181–186.
    • (2010) Pharmacol. Biochem. Behav. , vol.96 , pp. 181-186
    • Evola, M.1    Hall, A.2    Wall, T.3    Young, A.4    Grammas, P.5
  • 49
    • 84863688106 scopus 로고    scopus 로고
    • Mitochondrial- and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers
    • Ferreiro, E., Baldeiras, I., Ferreira, I.L., Costa, R.O., Rego, A.C., Pereira, C.F., Oliveira, C.R., Mitochondrial- and endoplasmic reticulum-associated oxidative stress in Alzheimer's disease: from pathogenesis to biomarkers. Int. J. Cell Biol., 2012, 2012, 735206.
    • (2012) Int. J. Cell Biol. , vol.2012 , pp. 735206
    • Ferreiro, E.1    Baldeiras, I.2    Ferreira, I.L.3    Costa, R.O.4    Rego, A.C.5    Pereira, C.F.6    Oliveira, C.R.7
  • 50
    • 33947205041 scopus 로고    scopus 로고
    • Abnormal levels of prohibitin and ATP synthase in the substantia nigra and frontal cortex in Parkinson's disease
    • Ferrer, I., Perez, E., Dalfo, E., Barrachina, M., Abnormal levels of prohibitin and ATP synthase in the substantia nigra and frontal cortex in Parkinson's disease. Neurosci. Lett. 415 (2007), 205–209.
    • (2007) Neurosci. Lett. , vol.415 , pp. 205-209
    • Ferrer, I.1    Perez, E.2    Dalfo, E.3    Barrachina, M.4
  • 52
    • 84884908350 scopus 로고    scopus 로고
    • SOD2 in mitochondrial dysfunction and neurodegeneration
    • Flynn, J.M., Melov, S., SOD2 in mitochondrial dysfunction and neurodegeneration. Free Radic. Biol. Med. 62 (2013), 4–12.
    • (2013) Free Radic. Biol. Med. , vol.62 , pp. 4-12
    • Flynn, J.M.1    Melov, S.2
  • 53
    • 1542375990 scopus 로고    scopus 로고
    • The cognitive ability of an incident cohort of Parkinson's patients in the UK. The CamPaIGN study
    • Foltynie, T., Brayne, C.E., Robbins, T.W., Barker, R.A., The cognitive ability of an incident cohort of Parkinson's patients in the UK. The CamPaIGN study. Brain 127 (2004), 550–560.
    • (2004) Brain , vol.127 , pp. 550-560
    • Foltynie, T.1    Brayne, C.E.2    Robbins, T.W.3    Barker, R.A.4
  • 54
    • 76049085234 scopus 로고    scopus 로고
    • Mitochondrial superoxide dismutase SOD2 but not cytosolic SOD1, plays a critical role in protection against glutamate-induced oxidative stress and cell death in HT22 neuronal cells
    • Fukui, M., Zhu, B.T., Mitochondrial superoxide dismutase SOD2 but not cytosolic SOD1, plays a critical role in protection against glutamate-induced oxidative stress and cell death in HT22 neuronal cells. Free Radic. Biol. Med. 48 (2010), 821–830.
    • (2010) Free Radic. Biol. Med. , vol.48 , pp. 821-830
    • Fukui, M.1    Zhu, B.T.2
  • 56
    • 84889564576 scopus 로고    scopus 로고
    • LRRK2 G2385R variant carriers of female Parkinson's disease are more susceptible to motor fluctuation
    • Gao, C., Pang, H., Luo, X.G., Ren, Y., Shang, H., He, Z.Y., LRRK2 G2385R variant carriers of female Parkinson's disease are more susceptible to motor fluctuation. J. Neurol. 260 (2013), 2884–2889.
    • (2013) J. Neurol. , vol.260 , pp. 2884-2889
    • Gao, C.1    Pang, H.2    Luo, X.G.3    Ren, Y.4    Shang, H.5    He, Z.Y.6
  • 57
    • 0034798193 scopus 로고    scopus 로고
    • Genetics of parkinson's disease
    • Gasser, T., Genetics of parkinson's disease. J. Neurol. 248 (2001), 833–840.
    • (2001) J. Neurol. , vol.248 , pp. 833-840
    • Gasser, T.1
  • 59
    • 84863624459 scopus 로고    scopus 로고
    • Loss of DJ-1 does not affect mitochondrial respiration but increases ROS production and mitochondrial permeability transition pore opening
    • Giaime, E., Yamaguchi, H., Gautier, C.A., Kitada, T., Shen, J., Loss of DJ-1 does not affect mitochondrial respiration but increases ROS production and mitochondrial permeability transition pore opening. PLoS One, 7, 2012, e40501.
    • (2012) PLoS One , vol.7 , pp. e40501
    • Giaime, E.1    Yamaguchi, H.2    Gautier, C.A.3    Kitada, T.4    Shen, J.5
  • 60
    • 84904093190 scopus 로고    scopus 로고
    • Abeta and tau toxicities in Alzheimer's are linked via oxidative stress-induced p38 activation: protective role of vitamin E
    • Giraldo, E., Lloret, A., Fuchsberger, T., Vina, J., Abeta and tau toxicities in Alzheimer's are linked via oxidative stress-induced p38 activation: protective role of vitamin E. Redox Biol. 2 (2014), 873–877.
    • (2014) Redox Biol. , vol.2 , pp. 873-877
    • Giraldo, E.1    Lloret, A.2    Fuchsberger, T.3    Vina, J.4
  • 62
    • 33748433789 scopus 로고    scopus 로고
    • Restoration of SHIP-1 activity in human leukemic cells modifies NF-kappaB activation pathway and cellular survival upon oxidative stress
    • Gloire, G., Charlier, E., Rahmouni, S., Volanti, C., Chariot, A., Erneux, C., Piette, J., Restoration of SHIP-1 activity in human leukemic cells modifies NF-kappaB activation pathway and cellular survival upon oxidative stress. Oncogene 25 (2006), 5485–5494.
    • (2006) Oncogene , vol.25 , pp. 5485-5494
    • Gloire, G.1    Charlier, E.2    Rahmouni, S.3    Volanti, C.4    Chariot, A.5    Erneux, C.6    Piette, J.7
  • 63
    • 33750523632 scopus 로고    scopus 로고
    • NF-kappaB activation by reactive oxygen species: fifteen years later
    • Gloire, G., Legrand-Poels, S., Piette, J., NF-kappaB activation by reactive oxygen species: fifteen years later. Biochem. Pharmacol. 72 (2006), 1493–1505.
    • (2006) Biochem. Pharmacol. , vol.72 , pp. 1493-1505
    • Gloire, G.1    Legrand-Poels, S.2    Piette, J.3
  • 67
    • 33947660448 scopus 로고    scopus 로고
    • Nucleotide receptor signalling and the generation of reactive oxygen species
    • Guerra, A.N., Gavala, M.L., Chung, H.S., Bertics, P.J., Nucleotide receptor signalling and the generation of reactive oxygen species. Purinergic Signal. 3 (2007), 39–51.
    • (2007) Purinergic Signal. , vol.3 , pp. 39-51
    • Guerra, A.N.1    Gavala, M.L.2    Chung, H.S.3    Bertics, P.J.4
  • 68
    • 84887906733 scopus 로고    scopus 로고
    • 3,4-dihydroxybenzalacetone protects against Parkinson's disease-related neurotoxin 6-OHDA through Akt/Nrf2/glutathione pathway
    • Gunjima, K., Tomiyama, R., Takakura, K., Yamada, T., Hashida, K., Nakamura, Y., Konishi, T., Matsugo, S., Hori, O., 3,4-dihydroxybenzalacetone protects against Parkinson's disease-related neurotoxin 6-OHDA through Akt/Nrf2/glutathione pathway. J. Cell. Biochem. 115 (2014), 151–160.
    • (2014) J. Cell. Biochem. , vol.115 , pp. 151-160
    • Gunjima, K.1    Tomiyama, R.2    Takakura, K.3    Yamada, T.4    Hashida, K.5    Nakamura, Y.6    Konishi, T.7    Matsugo, S.8    Hori, O.9
  • 70
    • 33745013111 scopus 로고    scopus 로고
    • Oxidative stress and neurodegeneration: where are we now?
    • Halliwell, B., Oxidative stress and neurodegeneration: where are we now?. J. Neurochem. 97 (2006), 1634–1658.
    • (2006) J. Neurochem. , vol.97 , pp. 1634-1658
    • Halliwell, B.1
  • 71
    • 61849088424 scopus 로고    scopus 로고
    • Tau phosphorylation: the therapeutic challenge for neurodegenerative disease
    • Hanger, D.P., Anderton, B.H., Noble, W., Tau phosphorylation: the therapeutic challenge for neurodegenerative disease. Trends Mol. Med. 15 (2009), 112–119.
    • (2009) Trends Mol. Med. , vol.15 , pp. 112-119
    • Hanger, D.P.1    Anderton, B.H.2    Noble, W.3
  • 72
    • 77953084081 scopus 로고    scopus 로고
    • DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function
    • Hao, L.Y., Giasson, B.I., Bonini, N.M., DJ-1 is critical for mitochondrial function and rescues PINK1 loss of function. Proc. Natl. Acad. Sci. U. S. A. 107 (2010), 9747–9752.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 9747-9752
    • Hao, L.Y.1    Giasson, B.I.2    Bonini, N.M.3
  • 73
    • 70350759686 scopus 로고    scopus 로고
    • Pathogenesis of familial Parkinson's disease: new insights based on monogenic forms of Parkinson's disease
    • Hatano, T., Kubo, S., Sato, S., Hattori, N., Pathogenesis of familial Parkinson's disease: new insights based on monogenic forms of Parkinson's disease. J. Neurochem. 111 (2009), 1075–1093.
    • (2009) J. Neurochem. , vol.111 , pp. 1075-1093
    • Hatano, T.1    Kubo, S.2    Sato, S.3    Hattori, N.4
  • 74
    • 84878862568 scopus 로고    scopus 로고
    • A novel melatonin agonist Neu-P11 facilitates memory performance and improves cognitive impairment in a rat model of Alzheimer' disease
    • He, P., Ouyang, X., Zhou, S., Yin, W., Tang, C., Laudon, M., Tian, S., A novel melatonin agonist Neu-P11 facilitates memory performance and improves cognitive impairment in a rat model of Alzheimer' disease. Horm. Behav. 64 (2013), 1–7.
    • (2013) Horm. Behav. , vol.64 , pp. 1-7
    • He, P.1    Ouyang, X.2    Zhou, S.3    Yin, W.4    Tang, C.5    Laudon, M.6    Tian, S.7
  • 75
    • 55849122639 scopus 로고    scopus 로고
    • Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis
    • Henchcliffe, C., Beal, M.F., Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis. Nat. Clin. Pract. Neurol. 4 (2008), 600–609.
    • (2008) Nat. Clin. Pract. Neurol. , vol.4 , pp. 600-609
    • Henchcliffe, C.1    Beal, M.F.2
  • 76
    • 84885452439 scopus 로고    scopus 로고
    • Surprising behavioral and neurochemical enhancements in mice with combined mutations linked to Parkinson's disease
    • Hennis, M.R., Marvin, M.A., Taylor, C.M., Goldberg 2nd, M.S., Surprising behavioral and neurochemical enhancements in mice with combined mutations linked to Parkinson's disease. Neurobiol. Dis. 62 (2014), 113–123.
    • (2014) Neurobiol. Dis. , vol.62 , pp. 113-123
    • Hennis, M.R.1    Marvin, M.A.2    Taylor, C.M.3    Goldberg 2nd, M.S.4
  • 77
    • 77449141215 scopus 로고    scopus 로고
    • LRRK2 enhances oxidative stress-induced neurotoxicity via its kinase activity
    • Heo, H.Y., Park, J.M., Kim, C.H., Han, B.S., Kim, K.S., Seol, W., LRRK2 enhances oxidative stress-induced neurotoxicity via its kinase activity. Exp. Cell Res. 316 (2010), 649–656.
    • (2010) Exp. Cell Res. , vol.316 , pp. 649-656
    • Heo, H.Y.1    Park, J.M.2    Kim, C.H.3    Han, B.S.4    Kim, K.S.5    Seol, W.6
  • 78
    • 84893865299 scopus 로고    scopus 로고
    • NADPH oxidase and the degeneration of dopaminergic neurons in parkinsonian mice
    • Hernandes, M.S., Cafe-Mendes, C.C., Britto, L.R., NADPH oxidase and the degeneration of dopaminergic neurons in parkinsonian mice. Oxid. Med. Cell Longev., 2013, 2013, 157857.
    • (2013) Oxid. Med. Cell Longev. , vol.2013 , pp. 157857
    • Hernandes, M.S.1    Cafe-Mendes, C.C.2    Britto, L.R.3
  • 80
    • 36749075156 scopus 로고    scopus 로고
    • P2X(7) receptor-mediated reactive oxygen and nitrogen species formation: from receptor to generators
    • Hewinson, J., Mackenzie, A.B., P2X(7) receptor-mediated reactive oxygen and nitrogen species formation: from receptor to generators. Biochem. Soc. Trans. 35 (2007), 1168–1170.
    • (2007) Biochem. Soc. Trans. , vol.35 , pp. 1168-1170
    • Hewinson, J.1    Mackenzie, A.B.2
  • 81
    • 84864071076 scopus 로고    scopus 로고
    • Mitochondrial neuronal uncoupling proteins: a target for potential disease-modification in Parkinson's disease
    • Ho, P.W., Ho, J.W., Liu, H.F., So, D.H., Tse, Z.H., Chan, K.H., Ramsden, D.B., Ho, S.L., Mitochondrial neuronal uncoupling proteins: a target for potential disease-modification in Parkinson's disease. Transl. Neurodegener., 1, 2012, 3.
    • (2012) Transl. Neurodegener. , vol.1 , pp. 3
    • Ho, P.W.1    Ho, J.W.2    Liu, H.F.3    So, D.H.4    Tse, Z.H.5    Chan, K.H.6    Ramsden, D.B.7    Ho, S.L.8
  • 83
    • 79955512752 scopus 로고    scopus 로고
    • Lack of neuroprotection in the absence of P2X7 receptors in toxin-induced animal models of Parkinson's disease
    • Hracsko, Z., Baranyi, M., Csolle, C., Goloncser, F., Madarasz, E., Kittel, A., Sperlagh, B., Lack of neuroprotection in the absence of P2X7 receptors in toxin-induced animal models of Parkinson's disease. Mol. Neurodegener., 6, 2011, 28.
    • (2011) Mol. Neurodegener. , vol.6 , pp. 28
    • Hracsko, Z.1    Baranyi, M.2    Csolle, C.3    Goloncser, F.4    Madarasz, E.5    Kittel, A.6    Sperlagh, B.7
  • 84
    • 84883180845 scopus 로고    scopus 로고
    • Role of oxidative stress in Parkinson's disease
    • Hwang, O., Role of oxidative stress in Parkinson's disease. Exp. Neurobiol. 22 (2013), 11–17.
    • (2013) Exp. Neurobiol. , vol.22 , pp. 11-17
    • Hwang, O.1
  • 85
    • 77953363542 scopus 로고    scopus 로고
    • DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex
    • Im, J.Y., Lee, K.W., Junn, E., Mouradian, M.M., DJ-1 protects against oxidative damage by regulating the thioredoxin/ASK1 complex. Neurosci. Res. 67 (2010), 203–208.
    • (2010) Neurosci. Res. , vol.67 , pp. 203-208
    • Im, J.Y.1    Lee, K.W.2    Junn, E.3    Mouradian, M.M.4
  • 86
    • 84863518914 scopus 로고    scopus 로고
    • DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway
    • Im, J.Y., Lee, K.W., Woo, J.M., Junn, E., Mouradian, M.M., DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway. Hum. Mol. Genet. 21 (2012), 3013–3024.
    • (2012) Hum. Mol. Genet. , vol.21 , pp. 3013-3024
    • Im, J.Y.1    Lee, K.W.2    Woo, J.M.3    Junn, E.4    Mouradian, M.M.5
  • 87
    • 84862761186 scopus 로고    scopus 로고
    • Diverse ubiquitin signaling in NF-kappaB activation
    • Iwai, K., Diverse ubiquitin signaling in NF-kappaB activation. Trends Cell Biol. 22 (2012), 355–364.
    • (2012) Trends Cell Biol. , vol.22 , pp. 355-364
    • Iwai, K.1
  • 88
    • 0037378026 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease
    • discussion S36–S28
    • Jenner, P., Oxidative stress in Parkinson's disease. Ann. Neurol. 53:Suppl 3 (2003), S26–S36 discussion S36–S28.
    • (2003) Ann. Neurol. , vol.53 , pp. S26-S36
    • Jenner, P.1
  • 90
    • 84930086236 scopus 로고    scopus 로고
    • P2X7 receptor is critical in alpha-synuclein?mediated microglial NADPH oxidase activation
    • Jiang, T., Hoekstra, J., Heng, X., Kang, W., Ding, J., Liu, J., Chen, S., Zhang, J., P2X7 receptor is critical in alpha-synuclein?mediated microglial NADPH oxidase activation. Neurobiol. Aging 36 (2015), 2304–2318.
    • (2015) Neurobiol. Aging , vol.36 , pp. 2304-2318
    • Jiang, T.1    Hoekstra, J.2    Heng, X.3    Kang, W.4    Ding, J.5    Liu, J.6    Chen, S.7    Zhang, J.8
  • 91
    • 84871377044 scopus 로고    scopus 로고
    • Microglia in Alzheimer's disease
    • Jin, L.W., Microglia in Alzheimer's disease. Int. J. Alzheimers Dis., 2012, 2012, 598371.
    • (2012) Int. J. Alzheimers Dis. , vol.2012 , pp. 598371
    • Jin, L.W.1
  • 93
    • 63049138430 scopus 로고    scopus 로고
    • Mitochondrial localization of DJ-1 leads to enhanced neuroprotection
    • Junn, E., Jang, W.H., Zhao, X., Jeong, B.S., Mouradian, M.M., Mitochondrial localization of DJ-1 leads to enhanced neuroprotection. J. Neurosci. Res. 87 (2009), 123–129.
    • (2009) J. Neurosci. Res. , vol.87 , pp. 123-129
    • Junn, E.1    Jang, W.H.2    Zhao, X.3    Jeong, B.S.4    Mouradian, M.M.5
  • 96
    • 84929579664 scopus 로고    scopus 로고
    • Cerebral dopamine neurotrophic factor improves long-term memory in APP/PS1 transgenic mice modeling Alzheimer's disease as well as in wild-type mice
    • Kemppainen, S., Lindholm, P., Galli, E., Lahtinen, H.M., Koivisto, H., Hamalainen, E., Saarma, M., Tanila, H., Cerebral dopamine neurotrophic factor improves long-term memory in APP/PS1 transgenic mice modeling Alzheimer's disease as well as in wild-type mice. Behav. Brain Res. 291 (2015), 1–11.
    • (2015) Behav. Brain Res. , vol.291 , pp. 1-11
    • Kemppainen, S.1    Lindholm, P.2    Galli, E.3    Lahtinen, H.M.4    Koivisto, H.5    Hamalainen, E.6    Saarma, M.7    Tanila, H.8
  • 97
    • 84883639808 scopus 로고    scopus 로고
    • Ameliorative effect of Sida cordifolia in rotenone induced oxidative stress model of Parkinson's disease
    • Khurana, N., Gajbhiye, A., Ameliorative effect of Sida cordifolia in rotenone induced oxidative stress model of Parkinson's disease. Neurotoxicology 39 (2013), 57–64.
    • (2013) Neurotoxicology , vol.39 , pp. 57-64
    • Khurana, N.1    Gajbhiye, A.2
  • 98
    • 0035890154 scopus 로고    scopus 로고
    • Proteomic and functional evidence for a P2X7 receptor signalling complex
    • Kim, M., Jiang, L.H., Wilson, H.L., North, R.A., Surprenant, A., Proteomic and functional evidence for a P2X7 receptor signalling complex. EMBO J. 20 (2001), 6347–6358.
    • (2001) EMBO J. , vol.20 , pp. 6347-6358
    • Kim, M.1    Jiang, L.H.2    Wilson, H.L.3    North, R.A.4    Surprenant, A.5
  • 99
    • 84862847822 scopus 로고    scopus 로고
    • Antioxidant enzymatic activities in Alzheimer's disease: the relationship to acetylcholinesterase inhibitors
    • Klugman, A., Naughton, D.P., Isaac, M., Shah, I., Petroczi, A., Tabet, N., Antioxidant enzymatic activities in Alzheimer's disease: the relationship to acetylcholinesterase inhibitors. J. Alzheimers Dis. 30 (2012), 467–474.
    • (2012) J. Alzheimers Dis. , vol.30 , pp. 467-474
    • Klugman, A.1    Naughton, D.P.2    Isaac, M.3    Shah, I.4    Petroczi, A.5    Tabet, N.6
  • 100
    • 84873720037 scopus 로고    scopus 로고
    • Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cellline
    • Koriyama, Y., Nakayama, Y., Matsugo, S., Kato, S., Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cellline. Brain Res. 1499 (2013), 145–157.
    • (2013) Brain Res. , vol.1499 , pp. 145-157
    • Koriyama, Y.1    Nakayama, Y.2    Matsugo, S.3    Kato, S.4
  • 102
    • 0037291563 scopus 로고    scopus 로고
    • Purinergic modulation of neuronal activity in the mesolimbic dopaminergic system in vivo
    • Krugel, U., Kittner, H., Franke, H., Illes, P., Purinergic modulation of neuronal activity in the mesolimbic dopaminergic system in vivo. Synapse 47 (2003), 134–142.
    • (2003) Synapse , vol.47 , pp. 134-142
    • Krugel, U.1    Kittner, H.2    Franke, H.3    Illes, P.4
  • 103
    • 84884583819 scopus 로고    scopus 로고
    • Can parkin be a target for future treatment of Parkinson's disease?
    • Kubo, S., Hatano, T., Takanashi, M., Hattori, N., Can parkin be a target for future treatment of Parkinson's disease?. Expert Opin. Ther. Targets 17 (2013), 1133–1144.
    • (2013) Expert Opin. Ther. Targets , vol.17 , pp. 1133-1144
    • Kubo, S.1    Hatano, T.2    Takanashi, M.3    Hattori, N.4
  • 104
    • 79952106055 scopus 로고    scopus 로고
    • Differential regulation of BACE1 expression by oxidative and nitrosative signals
    • Kwak, Y.D., Wang, R., Li, J.J., Zhang, Y.W., Xu, H., Liao, F.F., Differential regulation of BACE1 expression by oxidative and nitrosative signals. Mol. Neurodegener., 6, 2011, 17.
    • (2011) Mol. Neurodegener. , vol.6 , pp. 17
    • Kwak, Y.D.1    Wang, R.2    Li, J.J.3    Zhang, Y.W.4    Xu, H.5    Liao, F.F.6
  • 105
    • 84893875778 scopus 로고    scopus 로고
    • Eucommia ulmoides Oliv. bark. attenuates 6-hydroxydopamine-induced neuronal cell death through inhibition of oxidative stress in SH-SY5Y cells
    • Kwon, S.H., Ma, S.X., Hong, S.I., Kim, S.Y., Lee, S.Y., Jang, C.G., Eucommia ulmoides Oliv. bark. attenuates 6-hydroxydopamine-induced neuronal cell death through inhibition of oxidative stress in SH-SY5Y cells. J. Ethnopharmacol. 152 (2014), 173–182.
    • (2014) J. Ethnopharmacol. , vol.152 , pp. 173-182
    • Kwon, S.H.1    Ma, S.X.2    Hong, S.I.3    Kim, S.Y.4    Lee, S.Y.5    Jang, C.G.6
  • 106
    • 38849197935 scopus 로고    scopus 로고
    • Structural impact of three Parkinsonism-associated missense mutations on human DJ-1
    • Lakshminarasimhan, M., Maldonado, M.T., Zhou, W., Fink, A.L., Wilson, M.A., Structural impact of three Parkinsonism-associated missense mutations on human DJ-1. Biochemistry 47 (2008), 1381–1392.
    • (2008) Biochemistry , vol.47 , pp. 1381-1392
    • Lakshminarasimhan, M.1    Maldonado, M.T.2    Zhou, W.3    Fink, A.L.4    Wilson, M.A.5
  • 108
    • 79955670533 scopus 로고    scopus 로고
    • Ionotropic receptors in neuronal-astroglial signalling: what is the role of excitable molecules in non-excitable cells
    • Lalo, U., Pankratov, Y., Parpura, V., Verkhratsky, A., Ionotropic receptors in neuronal-astroglial signalling: what is the role of excitable molecules in non-excitable cells. Biochim. Biophys. Acta 1813 (2011), 992–1002.
    • (2011) Biochim. Biophys. Acta , vol.1813 , pp. 992-1002
    • Lalo, U.1    Pankratov, Y.2    Parpura, V.3    Verkhratsky, A.4
  • 110
    • 84885180238 scopus 로고    scopus 로고
    • Resolvin D1-mediated NOX2 inactivation rescues macrophages undertaking efferocytosis from oxidative stress-induced apoptosis
    • Lee, H.N., Surh, Y.J., Resolvin D1-mediated NOX2 inactivation rescues macrophages undertaking efferocytosis from oxidative stress-induced apoptosis. Biochem. Pharmacol. 86 (2013), 759–769.
    • (2013) Biochem. Pharmacol. , vol.86 , pp. 759-769
    • Lee, H.N.1    Surh, Y.J.2
  • 111
    • 78651108146 scopus 로고    scopus 로고
    • Mg2+ ions reduce microglial and THP-1 cell neurotoxicity by inhibiting Ca2+ entry through purinergic channels
    • Lee, M., Jantaratnotai, N., McGeer, E., McLarnon, J.G., McGeer, P.L., Mg2+ ions reduce microglial and THP-1 cell neurotoxicity by inhibiting Ca2+ entry through purinergic channels. Brain Res. 1369 (2011), 21–35.
    • (2011) Brain Res. , vol.1369 , pp. 21-35
    • Lee, M.1    Jantaratnotai, N.2    McGeer, E.3    McLarnon, J.G.4    McGeer, P.L.5
  • 112
    • 79954592028 scopus 로고    scopus 로고
    • 4-O-methylhonokiol attenuated beta-amyloid-induced memory impairment through reduction of oxidative damages via inactivation of p38 MAP kinase
    • Lee, Y.K., Choi, I.S., Ban, J.O., Lee, H.J., Lee, U.S., Han, S.B., Jung, J.K., Kim, Y.H., Kim, K.H., Oh, K.W., Hong, J.T., 4-O-methylhonokiol attenuated beta-amyloid-induced memory impairment through reduction of oxidative damages via inactivation of p38 MAP kinase. J. Nutr. Biochem. 22 (2011), 476–486.
    • (2011) J. Nutr. Biochem. , vol.22 , pp. 476-486
    • Lee, Y.K.1    Choi, I.S.2    Ban, J.O.3    Lee, H.J.4    Lee, U.S.5    Han, S.B.6    Jung, J.K.7    Kim, Y.H.8    Kim, K.H.9    Oh, K.W.10    Hong, J.T.11
  • 113
    • 84866900065 scopus 로고    scopus 로고
    • Mechanisms of oxidative damage in multiple sclerosis and neurodegenerative diseases: therapeutic modulation via fumaric acid esters
    • Lee, D.H., Gold, R., Linker, R.A., Mechanisms of oxidative damage in multiple sclerosis and neurodegenerative diseases: therapeutic modulation via fumaric acid esters. Int. J. Mol. Sci. 13 (2012), 11783–11803.
    • (2012) Int. J. Mol. Sci. , vol.13 , pp. 11783-11803
    • Lee, D.H.1    Gold, R.2    Linker, R.A.3
  • 114
    • 84856002072 scopus 로고    scopus 로고
    • Early induction of oxidative stress in mouse model of Alzheimer disease with reduced mitochondrial superoxide dismutase activity
    • Lee, H.P., Pancholi, N., Esposito, L., Previll, L.A., Wang, X., Zhu, X., Smith, M.A., Lee, H.G., Early induction of oxidative stress in mouse model of Alzheimer disease with reduced mitochondrial superoxide dismutase activity. PLoS One, 7, 2012, e28033.
    • (2012) PLoS One , vol.7 , pp. e28033
    • Lee, H.P.1    Pancholi, N.2    Esposito, L.3    Previll, L.A.4    Wang, X.5    Zhu, X.6    Smith, M.A.7    Lee, H.G.8
  • 115
    • 84897954401 scopus 로고    scopus 로고
    • CSF and brain indices of insulin resistance, oxidative stress and neuro-Inflammation in early versus late alzheimer's disease
    • Lee, S., Tong, M., Hang, S., Deochand, C., de la Monte, S., CSF and brain indices of insulin resistance, oxidative stress and neuro-Inflammation in early versus late alzheimer's disease. J. Alzheimers Dis. Parkinsonism, 3, 2013, 128.
    • (2013) J. Alzheimers Dis. Parkinsonism , vol.3 , pp. 128
    • Lee, S.1    Tong, M.2    Hang, S.3    Deochand, C.4    de la Monte, S.5
  • 116
    • 79952812955 scopus 로고    scopus 로고
    • The effect of apolipoprotein E (ApoE) genotype on biomarkers of amyloidogenesis: tau pathology and neurodegeneration in Alzheimer's disease
    • Leoni, V., The effect of apolipoprotein E (ApoE) genotype on biomarkers of amyloidogenesis: tau pathology and neurodegeneration in Alzheimer's disease. Clin. Chem. Lab. Med. 49 (2011), 375–383.
    • (2011) Clin. Chem. Lab. Med. , vol.49 , pp. 375-383
    • Leoni, V.1
  • 117
    • 33644990327 scopus 로고    scopus 로고
    • Interleukin-1beta induction of NFkappaB is partially regulated by H2O2-mediated activation of NFkappaB-inducing kinase
    • Li, Q., Engelhardt, J.F., Interleukin-1beta induction of NFkappaB is partially regulated by H2O2-mediated activation of NFkappaB-inducing kinase. J. Biol. Chem. 281 (2006), 1495–1505.
    • (2006) J. Biol. Chem. , vol.281 , pp. 1495-1505
    • Li, Q.1    Engelhardt, J.F.2
  • 120
    • 79951950516 scopus 로고    scopus 로고
    • Oxidative stress partially contributes to iron-induced alpha-synuclein aggregation in SK-N-SH cells
    • Li, W., Jiang, H., Song, N., Xie, J., Oxidative stress partially contributes to iron-induced alpha-synuclein aggregation in SK-N-SH cells. Neurotox. Res. 19 (2011), 435–442.
    • (2011) Neurotox. Res. , vol.19 , pp. 435-442
    • Li, W.1    Jiang, H.2    Song, N.3    Xie, J.4
  • 121
    • 84886839508 scopus 로고    scopus 로고
    • Treatment with hydrogen molecules prevents RANKL-induced osteoclast differentiation associated with inhibition of ROS formation and inactivation of MAPK, AKT and NF-kappa B pathways in murine RAW264.7 cells
    • Li, D.Z., Zhang, Q.X., Dong, X.X., Li, H.D., Ma, X., Treatment with hydrogen molecules prevents RANKL-induced osteoclast differentiation associated with inhibition of ROS formation and inactivation of MAPK, AKT and NF-kappa B pathways in murine RAW264.7 cells. J. Bone Miner. Metab. 32 (2014), 494–504.
    • (2014) J. Bone Miner. Metab. , vol.32 , pp. 494-504
    • Li, D.Z.1    Zhang, Q.X.2    Dong, X.X.3    Li, H.D.4    Ma, X.5
  • 122
    • 2942731516 scopus 로고    scopus 로고
    • Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation
    • Liao, G., Zhang, M., Harhaj, E.W., Sun, S.C., Regulation of the NF-kappaB-inducing kinase by tumor necrosis factor receptor-associated factor 3-induced degradation. J. Biol. Chem. 279 (2004), 26243–26250.
    • (2004) J. Biol. Chem. , vol.279 , pp. 26243-26250
    • Liao, G.1    Zhang, M.2    Harhaj, E.W.3    Sun, S.C.4
  • 123
    • 44549085003 scopus 로고    scopus 로고
    • Bromocriptine activates NQO1 via Nrf2-PI3K/Akt signaling: novel cytoprotective mechanism against oxidative damage
    • Lim, J.H., Kim, K.M., Kim, S.W., Hwang, O., Choi, H.J., Bromocriptine activates NQO1 via Nrf2-PI3K/Akt signaling: novel cytoprotective mechanism against oxidative damage. Pharmacol. Res. 57 (2008), 325–331.
    • (2008) Pharmacol. Res. , vol.57 , pp. 325-331
    • Lim, J.H.1    Kim, K.M.2    Kim, S.W.3    Hwang, O.4    Choi, H.J.5
  • 124
    • 33750347347 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
    • Lin, M.T., Beal, M.F., Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature 443 (2006), 787–795.
    • (2006) Nature , vol.443 , pp. 787-795
    • Lin, M.T.1    Beal, M.F.2
  • 127
    • 67650921433 scopus 로고    scopus 로고
    • Vitamin E paradox in Alzheimer's disease: it does not prevent loss of cognition and may even be detrimental
    • Lloret, A., Badia, M.C., Mora, N.J., Pallardo, F.V., Alonso, M.D., Vina, J., Vitamin E paradox in Alzheimer's disease: it does not prevent loss of cognition and may even be detrimental. J. Alzheimers Dis. 17 (2009), 143–149.
    • (2009) J. Alzheimers Dis. , vol.17 , pp. 143-149
    • Lloret, A.1    Badia, M.C.2    Mora, N.J.3    Pallardo, F.V.4    Alonso, M.D.5    Vina, J.6
  • 129
    • 84891699279 scopus 로고    scopus 로고
    • Naringenin protects against 6-OHDA-induced neurotoxicity via activation of the Nrf2/ARE signaling pathway
    • Lou, H., Jing, X., Wei, X., Shi, H., Ren, D., Zhang, X., Naringenin protects against 6-OHDA-induced neurotoxicity via activation of the Nrf2/ARE signaling pathway. Neuropharmacology 79 (2014), 380–388.
    • (2014) Neuropharmacology , vol.79 , pp. 380-388
    • Lou, H.1    Jing, X.2    Wei, X.3    Shi, H.4    Ren, D.5    Zhang, X.6
  • 131
    • 77957028140 scopus 로고    scopus 로고
    • Microglial activation and chronic neurodegeneration
    • Lull, M.E., Block, M.L., Microglial activation and chronic neurodegeneration. Neurotherapeutics 7 (2010), 354–365.
    • (2010) Neurotherapeutics , vol.7 , pp. 354-365
    • Lull, M.E.1    Block, M.L.2
  • 133
    • 84872249795 scopus 로고    scopus 로고
    • Monomer DJ-1 and its N-terminal sequence are necessary for mitochondrial localization of DJ-1 mutants
    • Maita, C., Maita, H., Iguchi-Ariga, S.M., Ariga, H., Monomer DJ-1 and its N-terminal sequence are necessary for mitochondrial localization of DJ-1 mutants. PLoS One, 8, 2013, e54087.
    • (2013) PLoS One , vol.8 , pp. e54087
    • Maita, C.1    Maita, H.2    Iguchi-Ariga, S.M.3    Ariga, H.4
  • 134
    • 43049119301 scopus 로고    scopus 로고
    • Structural effects of Parkinson's disease linked DJ-1 mutations
    • Malgieri, G., Eliezer, D., Structural effects of Parkinson's disease linked DJ-1 mutations. Protein Sci. 17 (2008), 855–868.
    • (2008) Protein Sci. , vol.17 , pp. 855-868
    • Malgieri, G.1    Eliezer, D.2
  • 135
    • 34648843067 scopus 로고    scopus 로고
    • Mitochondrial cascade hypothesis of Alzheimer's disease: myth or reality?
    • Mancuso, M., Coppede, F., Murri, L., Siciliano, G., Mitochondrial cascade hypothesis of Alzheimer's disease: myth or reality?. Antioxid. Redox Signal. 9 (2007), 1631–1646.
    • (2007) Antioxid. Redox Signal. , vol.9 , pp. 1631-1646
    • Mancuso, M.1    Coppede, F.2    Murri, L.3    Siciliano, G.4
  • 136
    • 77955857970 scopus 로고    scopus 로고
    • Clinical features and pathogenesis of Alzheimer's disease: involvement of mitochondria and mitochondrial DNA
    • Mancuso, M., Orsucci, D., LoGerfo, A., Calsolaro, V., Siciliano, G., Clinical features and pathogenesis of Alzheimer's disease: involvement of mitochondria and mitochondrial DNA. Adv. Exp. Med. Biol. 685 (2010), 34–44.
    • (2010) Adv. Exp. Med. Biol. , vol.685 , pp. 34-44
    • Mancuso, M.1    Orsucci, D.2    LoGerfo, A.3    Calsolaro, V.4    Siciliano, G.5
  • 137
    • 84873708122 scopus 로고    scopus 로고
    • Neuroprotective effects of oral gallic acid against oxidative stress induced by 6-hydroxydopamine in rats
    • Mansouri, M.T., Farbood, Y., Sameri, M.J., Sarkaki, A., Naghizadeh, B., Rafeirad, M., Neuroprotective effects of oral gallic acid against oxidative stress induced by 6-hydroxydopamine in rats. Food Chem. 138 (2013), 1028–1033.
    • (2013) Food Chem. , vol.138 , pp. 1028-1033
    • Mansouri, M.T.1    Farbood, Y.2    Sameri, M.J.3    Sarkaki, A.4    Naghizadeh, B.5    Rafeirad, M.6
  • 142
    • 84883179994 scopus 로고    scopus 로고
    • SOD1 and DJ-1 converge at Nrf2 pathway: a clue for antioxidant therapeutic potential in neurodegeneration
    • Milani, P., Ambrosi, G., Gammoh, O., Blandini, F., Cereda, C., SOD1 and DJ-1 converge at Nrf2 pathway: a clue for antioxidant therapeutic potential in neurodegeneration. Oxid. Med. Cell Longev., 2013, 2013, 836760.
    • (2013) Oxid. Med. Cell Longev. , vol.2013 , pp. 836760
    • Milani, P.1    Ambrosi, G.2    Gammoh, O.3    Blandini, F.4    Cereda, C.5
  • 147
    • 84859760030 scopus 로고    scopus 로고
    • Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy
    • Mondragon-Rodriguez, S., Perry, G., Zhu, X., Boehm, J., Amyloid Beta and tau proteins as therapeutic targets for Alzheimer's disease treatment: rethinking the current strategy. Int. J. Alzheimers Dis., 2012, 2012, 630182.
    • (2012) Int. J. Alzheimers Dis. , vol.2012 , pp. 630182
    • Mondragon-Rodriguez, S.1    Perry, G.2    Zhu, X.3    Boehm, J.4
  • 148
    • 84866361333 scopus 로고    scopus 로고
    • Interaction of endogenous tau protein with synaptic proteins is regulated by N-methyl-D-aspartate receptor-dependent tau phosphorylation
    • Mondragon-Rodriguez, S., Trillaud-Doppia, E., Dudilot, A., Bourgeois, C., Lauzon, M., Leclerc, N., Boehm, J., Interaction of endogenous tau protein with synaptic proteins is regulated by N-methyl-D-aspartate receptor-dependent tau phosphorylation. J. Biol. Chem. 287 (2012), 32040–32053.
    • (2012) J. Biol. Chem. , vol.287 , pp. 32040-32053
    • Mondragon-Rodriguez, S.1    Trillaud-Doppia, E.2    Dudilot, A.3    Bourgeois, C.4    Lauzon, M.5    Leclerc, N.6    Boehm, J.7
  • 149
    • 0346434141 scopus 로고    scopus 로고
    • A missense mutation (L166P) in DJ-1 linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization
    • Moore, D.J., Zhang, L., Dawson, T.M., Dawson, V.L., A missense mutation (L166P) in DJ-1 linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization. J. Neurochem. 87 (2003), 1558–1567.
    • (2003) J. Neurochem. , vol.87 , pp. 1558-1567
    • Moore, D.J.1    Zhang, L.2    Dawson, T.M.3    Dawson, V.L.4
  • 150
    • 78650894319 scopus 로고    scopus 로고
    • Crosstalk of reactive oxygen species and NF-kappaB signaling
    • Morgan, M.J., Liu, Z.G., Crosstalk of reactive oxygen species and NF-kappaB signaling. Cell Res. 21 (2011), 103–115.
    • (2011) Cell Res. , vol.21 , pp. 103-115
    • Morgan, M.J.1    Liu, Z.G.2
  • 153
    • 79953903691 scopus 로고    scopus 로고
    • DJ-1 deficiency in astrocytes selectively enhances mitochondrial Complex I inhibitor-induced neurotoxicity
    • Mullett, S.J., Hinkle, D.A., DJ-1 deficiency in astrocytes selectively enhances mitochondrial Complex I inhibitor-induced neurotoxicity. J. Neurochem. 117 (2011), 375–387.
    • (2011) J. Neurochem. , vol.117 , pp. 375-387
    • Mullett, S.J.1    Hinkle, D.A.2
  • 154
    • 65549156198 scopus 로고    scopus 로고
    • Astrocyte cultures exhibit P2X7 receptor channel opening in the absence of exogenous ligands
    • Nagasawa, K., Escartin, C., Swanson, R.A., Astrocyte cultures exhibit P2X7 receptor channel opening in the absence of exogenous ligands. Glia 57 (2009), 622–633.
    • (2009) Glia , vol.57 , pp. 622-633
    • Nagasawa, K.1    Escartin, C.2    Swanson, R.A.3
  • 155
    • 84884556412 scopus 로고    scopus 로고
    • Bidirectional regulation of NF-kappaB by reactive oxygen species: a role of unfolded protein response
    • Nakajima, S., Kitamura, M., Bidirectional regulation of NF-kappaB by reactive oxygen species: a role of unfolded protein response. Free Radic. Biol. Med. 65 (2013), 162–174.
    • (2013) Free Radic. Biol. Med. , vol.65 , pp. 162-174
    • Nakajima, S.1    Kitamura, M.2
  • 157
    • 43149114461 scopus 로고    scopus 로고
    • Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage
    • Noguchi, T., Ishii, K., Fukutomi, H., Naguro, I., Matsuzawa, A., Takeda, K., Ichijo, H., Requirement of reactive oxygen species-dependent activation of ASK1-p38 MAPK pathway for extracellular ATP-induced apoptosis in macrophage. J. Biol. Chem. 283 (2008), 7657–7665.
    • (2008) J. Biol. Chem. , vol.283 , pp. 7657-7665
    • Noguchi, T.1    Ishii, K.2    Fukutomi, H.3    Naguro, I.4    Matsuzawa, A.5    Takeda, K.6    Ichijo, H.7
  • 158
    • 0038711511 scopus 로고    scopus 로고
    • Effects of oxidative and nitrative challenges on alpha-synuclein fibrillogenesis involve distinct mechanisms of protein modifications
    • Norris, E.H., Giasson, B.I., Ischiropoulos, H., Lee, V.M., Effects of oxidative and nitrative challenges on alpha-synuclein fibrillogenesis involve distinct mechanisms of protein modifications. J. Biol. Chem. 278 (2003), 27230–27240.
    • (2003) J. Biol. Chem. , vol.278 , pp. 27230-27240
    • Norris, E.H.1    Giasson, B.I.2    Ischiropoulos, H.3    Lee, V.M.4
  • 159
    • 0037174856 scopus 로고    scopus 로고
    • Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2)
    • Opazo, C., Huang, X., Cherny, R.A., Moir, R.D., Roher, A.E., White, A.R., Cappai, R., Masters, C.L., Tanzi, R.E., Inestrosa, N.C., Bush, A.I., Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2). J. Biol. Chem. 277 (2002), 40302–40308.
    • (2002) J. Biol. Chem. , vol.277 , pp. 40302-40308
    • Opazo, C.1    Huang, X.2    Cherny, R.A.3    Moir, R.D.4    Roher, A.E.5    White, A.R.6    Cappai, R.7    Masters, C.L.8    Tanzi, R.E.9    Inestrosa, N.C.10    Bush, A.I.11
  • 160
    • 77949654869 scopus 로고    scopus 로고
    • Inhibition of neuronal cell death after retinoic acid-induced down-regulation of P2X7 nucleotide receptor expression
    • Orellano, E.A., Rivera, O.J., Chevres, M., Chorna, N.E., Gonzalez, F.A., Inhibition of neuronal cell death after retinoic acid-induced down-regulation of P2X7 nucleotide receptor expression. Mol. Cell. Biochem. 337 (2010), 83–99.
    • (2010) Mol. Cell. Biochem. , vol.337 , pp. 83-99
    • Orellano, E.A.1    Rivera, O.J.2    Chevres, M.3    Chorna, N.E.4    Gonzalez, F.A.5
  • 161
    • 72649096229 scopus 로고    scopus 로고
    • Changes of some oxidative stress markers in the serum of patients with mild cognitive impairment and Alzheimer's disease
    • Padurariu, M., Ciobica, A., Hritcu, L., Stoica, B., Bild, W., Stefanescu, C., Changes of some oxidative stress markers in the serum of patients with mild cognitive impairment and Alzheimer's disease. Neurosci. Lett. 469 (2010), 6–10.
    • (2010) Neurosci. Lett. , vol.469 , pp. 6-10
    • Padurariu, M.1    Ciobica, A.2    Hritcu, L.3    Stoica, B.4    Bild, W.5    Stefanescu, C.6
  • 165
    • 84874663567 scopus 로고    scopus 로고
    • Curcumin inhibition of JNKs prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease through suppressing mitochondria dysfunction
    • Pan, J., Li, H., Ma, J.F., Tan, Y.Y., Xiao, Q., Ding, J.Q., Chen, S.D., Curcumin inhibition of JNKs prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease through suppressing mitochondria dysfunction. Transl. Neurodegener., 1, 2012, 16.
    • (2012) Transl. Neurodegener. , vol.1 , pp. 16
    • Pan, J.1    Li, H.2    Ma, J.F.3    Tan, Y.Y.4    Xiao, Q.5    Ding, J.Q.6    Chen, S.D.7
  • 166
    • 41749104745 scopus 로고    scopus 로고
    • Complex I deficiency in Parkinson's disease frontal cortex
    • Parker, W.D. Jr., Parks, J.K., Swerdlow, R.H., Complex I deficiency in Parkinson's disease frontal cortex. Brain Res. 1189 (2008), 215–218.
    • (2008) Brain Res. , vol.1189 , pp. 215-218
    • Parker, W.D.1    Parks, J.K.2    Swerdlow, R.H.3
  • 167
    • 84898059809 scopus 로고    scopus 로고
    • Capturing a reactive state of amyloid aggregates: NMR-based characterization of copper-bound Alzheimer disease amyloid beta-fibrils in a redox cycle
    • Parthasarathy, S., Yoo, B., McElheny, D., Tay, W., Ishii, Y., Capturing a reactive state of amyloid aggregates: NMR-based characterization of copper-bound Alzheimer disease amyloid beta-fibrils in a redox cycle. J. Biol. Chem. 289 (2014), 9998–10010.
    • (2014) J. Biol. Chem. , vol.289 , pp. 9998-10010
    • Parthasarathy, S.1    Yoo, B.2    McElheny, D.3    Tay, W.4    Ishii, Y.5
  • 168
    • 0038143359 scopus 로고    scopus 로고
    • P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease
    • Parvathenani, L.K., Tertyshnikova, S., Greco, C.R., Roberts, S.B., Robertson, B., Posmantur, R., P2X7 mediates superoxide production in primary microglia and is up-regulated in a transgenic mouse model of Alzheimer's disease. J. Biol. Chem. 278 (2003), 13309–13317.
    • (2003) J. Biol. Chem. , vol.278 , pp. 13309-13317
    • Parvathenani, L.K.1    Tertyshnikova, S.2    Greco, C.R.3    Roberts, S.B.4    Robertson, B.5    Posmantur, R.6
  • 169
    • 84884889978 scopus 로고    scopus 로고
    • Reprint of: revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse
    • Perfeito, R., Cunha-Oliveira, T., Rego, A.C., Reprint of: revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease-resemblance to the effect of amphetamine drugs of abuse. Free Radic. Biol. Med. 62 (2013), 186–201.
    • (2013) Free Radic. Biol. Med. , vol.62 , pp. 186-201
    • Perfeito, R.1    Cunha-Oliveira, T.2    Rego, A.C.3
  • 171
    • 0028137186 scopus 로고
    • Melatonin: a peroxyl radical scavenger more effective than vitamin E
    • Pieri, C., Marra, M., Moroni, F., Recchioni, R., Marcheselli, F., Melatonin: a peroxyl radical scavenger more effective than vitamin E. Life Sci. 55 (1994), PL271–276.
    • (1994) Life Sci. , vol.55 , pp. PL271-276
    • Pieri, C.1    Marra, M.2    Moroni, F.3    Recchioni, R.4    Marcheselli, F.5
  • 172
    • 33749426753 scopus 로고    scopus 로고
    • Dynamic modeling of alpha-synuclein aggregation for the sporadic and genetic forms of Parkinson's disease
    • Raichur, A., Vali, S., Gorin, F., Dynamic modeling of alpha-synuclein aggregation for the sporadic and genetic forms of Parkinson's disease. Neuroscience 142 (2006), 859–870.
    • (2006) Neuroscience , vol.142 , pp. 859-870
    • Raichur, A.1    Vali, S.2    Gorin, F.3
  • 173
    • 39149122810 scopus 로고    scopus 로고
    • Amyloid beta: mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease
    • Reddy, P.H., Beal, M.F., Amyloid beta: mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease. Trends Mol. Med. 14 (2008), 45–53.
    • (2008) Trends Mol. Med. , vol.14 , pp. 45-53
    • Reddy, P.H.1    Beal, M.F.2
  • 174
    • 75149145165 scopus 로고    scopus 로고
    • Use of genetic variation as biomarkers for mild cognitive impairment and progression of mild cognitive impairment to dementia
    • Reitz, C., Mayeux, R., Use of genetic variation as biomarkers for mild cognitive impairment and progression of mild cognitive impairment to dementia. J. Alzheimers Dis. 19 (2010), 229–251.
    • (2010) J. Alzheimers Dis. , vol.19 , pp. 229-251
    • Reitz, C.1    Mayeux, R.2
  • 177
    • 77957980268 scopus 로고    scopus 로고
    • P4-344: oral curcumin for the treatment of mild-to-moderate Alzheimer's disease: tolerability and clinical and biomarker efficacy results of a placebo-controlled 24-week study
    • Ringman, J.M., Cole, G., Teng, E., Badmaev, V., Bardens, J., Frautschy, S., Rosario, E., Fein, J., Porter, V., Vanek, Z., P4-344: oral curcumin for the treatment of mild-to-moderate Alzheimer's disease: tolerability and clinical and biomarker efficacy results of a placebo-controlled 24-week study. Alzheimer Dement., 4, 2008, T774.
    • (2008) Alzheimer Dement. , vol.4 , pp. T774
    • Ringman, J.M.1    Cole, G.2    Teng, E.3    Badmaev, V.4    Bardens, J.5    Frautschy, S.6    Rosario, E.7    Fein, J.8    Porter, V.9    Vanek, Z.10
  • 178
    • 84877894117 scopus 로고    scopus 로고
    • Down-regulation of LRRK2 in control and DAT transfected HEK cells increases manganese-induced oxidative stress and cell toxicity
    • Roth, J.A., Eichhorn, M., Down-regulation of LRRK2 in control and DAT transfected HEK cells increases manganese-induced oxidative stress and cell toxicity. Neurotoxicology 37 (2013), 100–107.
    • (2013) Neurotoxicology , vol.37 , pp. 100-107
    • Roth, J.A.1    Eichhorn, M.2
  • 179
    • 33749534896 scopus 로고    scopus 로고
    • Production of nerve growth factor by beta-amyloid-stimulated astrocytes induces p75NTR-dependent tau hyperphosphorylation in cultured hippocampal neurons
    • Saez, E.T., Pehar, M., Vargas, M.R., Barbeito, L., Maccioni, R.B., Production of nerve growth factor by beta-amyloid-stimulated astrocytes induces p75NTR-dependent tau hyperphosphorylation in cultured hippocampal neurons. J. Neurosci. Res. 84 (2006), 1098–1106.
    • (2006) J. Neurosci. Res. , vol.84 , pp. 1098-1106
    • Saez, E.T.1    Pehar, M.2    Vargas, M.R.3    Barbeito, L.4    Maccioni, R.B.5
  • 180
    • 84939946943 scopus 로고    scopus 로고
    • Activation of S1P(1) receptor regulates PI3 K/Akt/FoxO3a pathway in response to oxidative stress in PC12 cells
    • Safarian, F., Khallaghi, B., Ahmadiani, A., Dargahi, L., Activation of S1P(1) receptor regulates PI3 K/Akt/FoxO3a pathway in response to oxidative stress in PC12 cells. J. Mol. Neurosci. 56 (2015), 177–187.
    • (2015) J. Mol. Neurosci. , vol.56 , pp. 177-187
    • Safarian, F.1    Khallaghi, B.2    Ahmadiani, A.3    Dargahi, L.4
  • 181
    • 84884902071 scopus 로고    scopus 로고
    • Oxidative damage to macromolecules in human Parkinson disease and the rotenone model
    • Sanders, L.H., Greenamyre, J.T., Oxidative damage to macromolecules in human Parkinson disease and the rotenone model. Free Radic. Biol. Med. 62 (2013), 111–120.
    • (2013) Free Radic. Biol. Med. , vol.62 , pp. 111-120
    • Sanders, L.H.1    Greenamyre, J.T.2
  • 183
    • 61349137536 scopus 로고    scopus 로고
    • LRRK2 and neurodegeneration
    • Santpere, G., Ferrer, I., LRRK2 and neurodegeneration. Acta Neuropathol. 117 (2009), 227–246.
    • (2009) Acta Neuropathol. , vol.117 , pp. 227-246
    • Santpere, G.1    Ferrer, I.2
  • 184
    • 84892368806 scopus 로고    scopus 로고
    • Reprint of: nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs
    • Satoh, T., McKercher, S.R., Lipton, S.A., Reprint of: nrf2/ARE-mediated antioxidant actions of pro-electrophilic drugs. Free Radic. Biol. Med. 66 (2014), 45–57.
    • (2014) Free Radic. Biol. Med. , vol.66 , pp. 45-57
    • Satoh, T.1    McKercher, S.R.2    Lipton, S.A.3
  • 185
    • 42549125512 scopus 로고    scopus 로고
    • Review: familial Parkinson's disease-genetics, clinical phenotype and neuropathology in relation to the common sporadic form of the disease
    • Schiesling, C., Kieper, N., Seidel, K., Kruger, R., Review: familial Parkinson's disease-genetics, clinical phenotype and neuropathology in relation to the common sporadic form of the disease. Neuropathol. Appl. Neurobiol. 34 (2008), 255–271.
    • (2008) Neuropathol. Appl. Neurobiol. , vol.34 , pp. 255-271
    • Schiesling, C.1    Kieper, N.2    Seidel, K.3    Kruger, R.4
  • 186
    • 47749147258 scopus 로고    scopus 로고
    • Hydrogen peroxide promotes Abeta production through JNK-dependent activation of gamma-secretase
    • Shen, C., Chen, Y., Liu, H., Zhang, K., Zhang, T., Lin, A., Jing, N., Hydrogen peroxide promotes Abeta production through JNK-dependent activation of gamma-secretase. J. Biol. Chem. 283 (2008), 7721–17730.
    • (2008) J. Biol. Chem. , vol.283 , pp. 7721-17730
    • Shen, C.1    Chen, Y.2    Liu, H.3    Zhang, K.4    Zhang, T.5    Lin, A.6    Jing, N.7
  • 188
    • 78549239223 scopus 로고    scopus 로고
    • The serum protein and lipid oxidation marker levels in Alzheimer's disease and effects of cholinesterase inhibitors and antipsychotic drugs therapy
    • Sinem, F., Dildar, K., Gokhan, E., Melda, B., Orhan, Y., Filiz, M., The serum protein and lipid oxidation marker levels in Alzheimer's disease and effects of cholinesterase inhibitors and antipsychotic drugs therapy. Curr. Alzheimer Res. 7 (2010), 463–469.
    • (2010) Curr. Alzheimer Res. , vol.7 , pp. 463-469
    • Sinem, F.1    Dildar, K.2    Gokhan, E.3    Melda, B.4    Orhan, Y.5    Filiz, M.6
  • 189
    • 0036815572 scopus 로고    scopus 로고
    • Genetic variation of apolipoproteins in North Indians
    • Singh, P.P., Singh, M., Mastana, S.S., Genetic variation of apolipoproteins in North Indians. Hum. Biol. 74 (2002), 673–682.
    • (2002) Hum. Biol. , vol.74 , pp. 673-682
    • Singh, P.P.1    Singh, M.2    Mastana, S.S.3
  • 192
    • 67651184281 scopus 로고    scopus 로고
    • NOX enzymes in the central nervous system: from signaling to disease
    • Sorce, S., Krause, K.H., NOX enzymes in the central nervous system: from signaling to disease. Antioxid. Redox Signal. 11 (2009), 2481–2504.
    • (2009) Antioxid. Redox Signal. , vol.11 , pp. 2481-2504
    • Sorce, S.1    Krause, K.H.2
  • 194
    • 84881027032 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and oxidative stress in Parkinson's disease
    • Subramaniam, S.R., Chesselet, M.F., Mitochondrial dysfunction and oxidative stress in Parkinson's disease. Prog. Neurobiol. 106–107 (2013), 17–32.
    • (2013) Prog. Neurobiol. , vol.106-107 , pp. 17-32
    • Subramaniam, S.R.1    Chesselet, M.F.2
  • 195
    • 0033986037 scopus 로고    scopus 로고
    • Histochemically-reactive zinc in amyloid plaques angiopathy, and degenerating neurons of Alzheimer's diseased brains
    • Suh, S.W., Jensen, K.B., Jensen, M.S., Silva, D.S., Kesslak, P.J., Danscher, G., Frederickson, C.J., Histochemically-reactive zinc in amyloid plaques angiopathy, and degenerating neurons of Alzheimer's diseased brains. Brain Res. 852 (2000), 274–278.
    • (2000) Brain Res. , vol.852 , pp. 274-278
    • Suh, S.W.1    Jensen, K.B.2    Jensen, M.S.3    Silva, D.S.4    Kesslak, P.J.5    Danscher, G.6    Frederickson, C.J.7
  • 196
    • 0035985937 scopus 로고    scopus 로고
    • Endogenous antioxidant activities in relation to concurrent vitamins A C, and E intake in dementia
    • Tabet, N., Mantle, D., Walker, Z., Orrell, M., Endogenous antioxidant activities in relation to concurrent vitamins A C, and E intake in dementia. Int. Psychogeriatr. 14 (2002), 7–15.
    • (2002) Int. Psychogeriatr. , vol.14 , pp. 7-15
    • Tabet, N.1    Mantle, D.2    Walker, Z.3    Orrell, M.4
  • 199
    • 77956215147 scopus 로고    scopus 로고
    • Pathogenesis of sporadic Parkinson's disease: contribution of genetic and environmental risk factors
    • Takahashi, R., Kawamata, J., Takeuchi, H., Pathogenesis of sporadic Parkinson's disease: contribution of genetic and environmental risk factors. Rinsho Shinkeigaku 49 (2009), 885–887.
    • (2009) Rinsho Shinkeigaku , vol.49 , pp. 885-887
    • Takahashi, R.1    Kawamata, J.2    Takeuchi, H.3
  • 201
    • 77956047221 scopus 로고    scopus 로고
    • Protective effect of hydrogen sulphide against 6-OHDA-induced cell injury in SH-SY5Y cells involves PKC/PI3K/Akt pathway
    • Tiong, C.X., Lu, M., Bian, J.S., Protective effect of hydrogen sulphide against 6-OHDA-induced cell injury in SH-SY5Y cells involves PKC/PI3K/Akt pathway. Br. J. Pharmacol. 161 (2010), 467–480.
    • (2010) Br. J. Pharmacol. , vol.161 , pp. 467-480
    • Tiong, C.X.1    Lu, M.2    Bian, J.S.3
  • 203
    • 84860172516 scopus 로고    scopus 로고
    • N-Terminal acetylation is critical for forming alpha-helical oligomer of alpha-synuclein
    • Trexler, A.J., Rhoades, E., N-Terminal acetylation is critical for forming alpha-helical oligomer of alpha-synuclein. Protein Sci. 21 (2012), 601–605.
    • (2012) Protein Sci. , vol.21 , pp. 601-605
    • Trexler, A.J.1    Rhoades, E.2
  • 206
    • 67649771389 scopus 로고    scopus 로고
    • Oxidizable residues mediating protein stability and cytoprotective interaction of DJ-1 with apoptosis signal-regulating kinase 1
    • Waak, J., Weber, S.S., Gorner, K., Schall, C., Ichijo, H., Stehle, T., Kahle, P.J., Oxidizable residues mediating protein stability and cytoprotective interaction of DJ-1 with apoptosis signal-regulating kinase 1. J. Biol. Chem. 284 (2009), 14245–14257.
    • (2009) J. Biol. Chem. , vol.284 , pp. 14245-14257
    • Waak, J.1    Weber, S.S.2    Gorner, K.3    Schall, C.4    Ichijo, H.5    Stehle, T.6    Kahle, P.J.7
  • 208
    • 79953247926 scopus 로고    scopus 로고
    • Impaired CD200-CD200R-mediated microglia silencing enhances midbrain dopaminergic neurodegeneration: roles of aging superoxide, NADPH oxidase, and p38 MAPK
    • Wang, X.J., Zhang, S., Yan, Z.Q., Zhao, Y.X., Zhou, H.Y., Wang, Y., Lu, G.Q., Zhang, J.D., Impaired CD200-CD200R-mediated microglia silencing enhances midbrain dopaminergic neurodegeneration: roles of aging superoxide, NADPH oxidase, and p38 MAPK. Free Radic. Biol. Med. 50 (2011), 1094–1106.
    • (2011) Free Radic. Biol. Med. , vol.50 , pp. 1094-1106
    • Wang, X.J.1    Zhang, S.2    Yan, Z.Q.3    Zhao, Y.X.4    Zhou, H.Y.5    Wang, Y.6    Lu, G.Q.7    Zhang, J.D.8
  • 209
    • 84855409709 scopus 로고    scopus 로고
    • DJ-1 modulates the expression of Cu/Zn-superoxide dismutase-1 through the Erk1/2-Elk1 pathway in neuroprotection
    • Wang, Z., Liu, J., Chen, S., Wang, Y., Cao, L., Zhang, Y., Kang, W., Li, H., Gui, Y., Ding, J., DJ-1 modulates the expression of Cu/Zn-superoxide dismutase-1 through the Erk1/2-Elk1 pathway in neuroprotection. Ann. Neurol. 70 (2011), 591–599.
    • (2011) Ann. Neurol. , vol.70 , pp. 591-599
    • Wang, Z.1    Liu, J.2    Chen, S.3    Wang, Y.4    Cao, L.5    Zhang, Y.6    Kang, W.7    Li, H.8    Gui, Y.9    Ding, J.10
  • 211
    • 84863116671 scopus 로고    scopus 로고
    • Redox sensing by proteins: oxidative modifications on cysteines and the consequent events
    • Wang, Y., Yang, J., Yi, J., Redox sensing by proteins: oxidative modifications on cysteines and the consequent events. Antioxid. Redox Signal. 16 (2012), 649–657.
    • (2012) Antioxid. Redox Signal. , vol.16 , pp. 649-657
    • Wang, Y.1    Yang, J.2    Yi, J.3
  • 212
    • 84894070483 scopus 로고    scopus 로고
    • Macrophage mitochondrial oxidative stress promotes atherosclerosis and nuclear factor-kappaB-mediated inflammation in macrophages
    • Wang, Y., Wang, G.Z., Rabinovitch, P.S., Tabas, I., Macrophage mitochondrial oxidative stress promotes atherosclerosis and nuclear factor-kappaB-mediated inflammation in macrophages. Circ. Res. 114 (2014), 421–433.
    • (2014) Circ. Res. , vol.114 , pp. 421-433
    • Wang, Y.1    Wang, G.Z.2    Rabinovitch, P.S.3    Tabas, I.4
  • 214
    • 84935835059 scopus 로고    scopus 로고
    • Wnt3a protects SH-SY5Y cells against 6-hydroxydopamine toxicity by restoration of mitochondria function
    • Wei, L., Ding, L., Mo, M.S., Lei, M., Zhang, L., Chen, K., Xu, P., Wnt3a protects SH-SY5Y cells against 6-hydroxydopamine toxicity by restoration of mitochondria function. Transl. Neurodegener., 4, 2015, 11.
    • (2015) Transl. Neurodegener. , vol.4 , pp. 11
    • Wei, L.1    Ding, L.2    Mo, M.S.3    Lei, M.4    Zhang, L.5    Chen, K.6    Xu, P.7
  • 215
    • 77449098331 scopus 로고    scopus 로고
    • Leucine-rich repeat kinase 2 gene-associated disease: redefining genotype-phenotype correlation
    • Wider, C., Dickson, D.W., Wszolek, Z.K., Leucine-rich repeat kinase 2 gene-associated disease: redefining genotype-phenotype correlation. Neurodegener. Dis. 7 (2010), 175–179.
    • (2010) Neurodegener. Dis. , vol.7 , pp. 175-179
    • Wider, C.1    Dickson, D.W.2    Wszolek, Z.K.3
  • 216
    • 79958199102 scopus 로고    scopus 로고
    • The role of cysteine oxidation in DJ-1 function and dysfunction
    • Wilson, M.A., The role of cysteine oxidation in DJ-1 function and dysfunction. Antioxid. Redox Signal. 15 (2011), 111–122.
    • (2011) Antioxid. Redox Signal. , vol.15 , pp. 111-122
    • Wilson, M.A.1
  • 217
    • 57449104348 scopus 로고    scopus 로고
    • Sustained oxidative stress inhibits NF-kappaB activation partially via inactivating the proteasome
    • Wu, M., Bian, Q., Liu, Y., Fernandes, A.F., Taylor, A., Pereira, P., Shang, F., Sustained oxidative stress inhibits NF-kappaB activation partially via inactivating the proteasome. Free Radic. Biol. Med. 46 (2009), 62–69.
    • (2009) Free Radic. Biol. Med. , vol.46 , pp. 62-69
    • Wu, M.1    Bian, Q.2    Liu, Y.3    Fernandes, A.F.4    Taylor, A.5    Pereira, P.6    Shang, F.7
  • 218
    • 80053452983 scopus 로고    scopus 로고
    • Beneficial role of Nrf2 in regulating NADPH generation and consumption
    • Wu, K.C., Cui, J.Y., Klaassen, C.D., Beneficial role of Nrf2 in regulating NADPH generation and consumption. Toxicol. Sci. 123 (2011), 590–600.
    • (2011) Toxicol. Sci. , vol.123 , pp. 590-600
    • Wu, K.C.1    Cui, J.Y.2    Klaassen, C.D.3
  • 220
  • 222
    • 67649739088 scopus 로고    scopus 로고
    • RAGE and Alzheimer's disease: a progression factor for amyloid-beta-induced cellular perturbation?
    • Yan, S.D., Bierhaus, A., Nawroth, P.P., Stern, D.M., RAGE and Alzheimer's disease: a progression factor for amyloid-beta-induced cellular perturbation?. J. Alzheimers Dis. 16 (2009), 833–843.
    • (2009) J. Alzheimers Dis. , vol.16 , pp. 833-843
    • Yan, S.D.1    Bierhaus, A.2    Nawroth, P.P.3    Stern, D.M.4
  • 225
    • 34547676083 scopus 로고    scopus 로고
    • Downregulation of parkin damages antioxidant defenses and enhances proteasome inhibition-induced toxicity in PC12 cells
    • Yang, H., Zhou, H.Y., Li, B., Niu, G.Z., Chen, S.D., Downregulation of parkin damages antioxidant defenses and enhances proteasome inhibition-induced toxicity in PC12 cells. J. Neuroimmune Pharmacol. 2 (2007), 276–283.
    • (2007) J. Neuroimmune Pharmacol. , vol.2 , pp. 276-283
    • Yang, H.1    Zhou, H.Y.2    Li, B.3    Niu, G.Z.4    Chen, S.D.5
  • 226
    • 84862308648 scopus 로고    scopus 로고
    • LRRK2 kinase activity mediates toxic interactions between genetic mutation and oxidative stress in a Drosophila model: suppression by curcumin
    • Yang, D., Li, T., Liu, Z., Arbez, N., Yan, J., Moran, T.H., Ross, C.A., Smith, W.W., LRRK2 kinase activity mediates toxic interactions between genetic mutation and oxidative stress in a Drosophila model: suppression by curcumin. Neurobiol. Dis. 47 (2012), 385–392.
    • (2012) Neurobiol. Dis. , vol.47 , pp. 385-392
    • Yang, D.1    Li, T.2    Liu, Z.3    Arbez, N.4    Yan, J.5    Moran, T.H.6    Ross, C.A.7    Smith, W.W.8
  • 227
    • 84901017315 scopus 로고    scopus 로고
    • Mitochondrial dysfunction driven by the LRRK2-mediated pathway is associated with loss of Purkinje cells and motor coordination deficits in diabetic rat model
    • Yang, S., Xia, C., Li, S., Du, L., Zhang, L., Hu, Y., Mitochondrial dysfunction driven by the LRRK2-mediated pathway is associated with loss of Purkinje cells and motor coordination deficits in diabetic rat model. Cell. Death. Dis., 5, 2014, e1217.
    • (2014) Cell. Death. Dis. , vol.5 , pp. e1217
    • Yang, S.1    Xia, C.2    Li, S.3    Du, L.4    Zhang, L.5    Hu, Y.6
  • 230
    • 20144389524 scopus 로고    scopus 로고
    • Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease
    • Zhang, W., Wang, T., Pei, Z., Miller, D.S., Wu, X., Block, M.L., Wilson, B., Zhou, Y., Hong, J.S., Zhang, J., Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease. FASEB J. 19 (2005), 533–542.
    • (2005) FASEB J. , vol.19 , pp. 533-542
    • Zhang, W.1    Wang, T.2    Pei, Z.3    Miller, D.S.4    Wu, X.5    Block, M.L.6    Wilson, B.7    Zhou, Y.8    Hong, J.S.9    Zhang, J.10
  • 231
    • 34547637625 scopus 로고    scopus 로고
    • Microglial PHOX and Mac-1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and A53T mutant alpha-synuclein
    • Zhang, W., Dallas, S., Zhang, D., Guo, J.P., Pang, H., Wilson, B., Miller, D.S., Chen, B., McGeer, P.L., Hong, J.S., Zhang, J., Microglial PHOX and Mac-1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and A53T mutant alpha-synuclein. Glia 55 (2007), 1178–1188.
    • (2007) Glia , vol.55 , pp. 1178-1188
    • Zhang, W.1    Dallas, S.2    Zhang, D.3    Guo, J.P.4    Pang, H.5    Wilson, B.6    Miller, D.S.7    Chen, B.8    McGeer, P.L.9    Hong, J.S.10    Zhang, J.11
  • 232
    • 84897401619 scopus 로고    scopus 로고
    • Microglial CR3 activation triggers long-term synaptic depression in the hippocampus via NADPH oxidase
    • Zhang, J., Malik, A., Choi, H.B., Ko, R.W., Dissing-Olesen, L., MacVicar, B.A., Microglial CR3 activation triggers long-term synaptic depression in the hippocampus via NADPH oxidase. Neuron 82 (2014), 195–207.
    • (2014) Neuron , vol.82 , pp. 195-207
    • Zhang, J.1    Malik, A.2    Choi, H.B.3    Ko, R.W.4    Dissing-Olesen, L.5    MacVicar, B.A.6
  • 233
    • 85015433890 scopus 로고    scopus 로고
    • Curcumin ameliorates memory decline via inhibiting BACE1 expression and beta-Amyloid pathology in 5xFAD transgenic mice
    • Zheng, K., Dai, X., Xiao, N., Wu, X., Wei, Z., Fang, W., Zhu, Y., Zhang, J., Chen, X., Curcumin ameliorates memory decline via inhibiting BACE1 expression and beta-Amyloid pathology in 5xFAD transgenic mice. Mol. Neurobiol., 2016.
    • (2016) Mol. Neurobiol.
    • Zheng, K.1    Dai, X.2    Xiao, N.3    Wu, X.4    Wei, Z.5    Fang, W.6    Zhu, Y.7    Zhang, J.8    Chen, X.9
  • 235
    • 84904349778 scopus 로고    scopus 로고
    • Decreasing oxidative stress and neuroinflammation with a multifunctional peptide rescues memory deficits in mice with Alzheimer disease
    • Zhou, W.W., Lu, S., Su, Y.J., Xue, D., Yu, X.L., Wang, S.W., Zhang, H., Xu, P.X., Xie, X.X., Liu, R.T., Decreasing oxidative stress and neuroinflammation with a multifunctional peptide rescues memory deficits in mice with Alzheimer disease. Free Radic. Biol. Med. 74 (2014), 50–63.
    • (2014) Free Radic. Biol. Med. , vol.74 , pp. 50-63
    • Zhou, W.W.1    Lu, S.2    Su, Y.J.3    Xue, D.4    Yu, X.L.5    Wang, S.W.6    Zhang, H.7    Xu, P.X.8    Xie, X.X.9    Liu, R.T.10
  • 236
    • 33846626477 scopus 로고    scopus 로고
    • Implication of PTEN in production of reactive oxygen species and neuronal death in vitro models of stroke and Parkinson's disease
    • Zhu, Y., Hoell, P., Ahlemeyer, B., Sure, U., Bertalanffy, H., Krieglstein, J., Implication of PTEN in production of reactive oxygen species and neuronal death in vitro models of stroke and Parkinson's disease. Neurochem. Int. 50 (2007), 507–516.
    • (2007) Neurochem. Int. , vol.50 , pp. 507-516
    • Zhu, Y.1    Hoell, P.2    Ahlemeyer, B.3    Sure, U.4    Bertalanffy, H.5    Krieglstein, J.6


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