메뉴 건너뛰기




Volumn 19, Issue 1, 2010, Pages 27-30

Why vitamin e therapy fails for treatment of Alzheimer's disease

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CARNITINE; GINKGO BILOBA EXTRACT; GLUTATHIONE PEROXIDASE; SELENIUM; THIOCTIC ACID;

EID: 75149148788     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2010-1238     Document Type: Note
Times cited : (47)

References (29)
  • 2
    • 33748423353 scopus 로고    scopus 로고
    • Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: An approach to understand pathological and biochemical alterations in AD
    • Sultana R, Boyd-Kimball D, Poon HF, Cai J, Pierce WM, Klein JB, Merchant M, Markesbery WR, Butterfield DA (2006) Redox proteomics identification of oxidized proteins in Alzheimer's disease hippocampus and cerebellum: an approach to understand pathological and biochemical alterations in AD. Neurobiol Aging 27, 1564-1576.
    • (2006) Neurobiol Aging , vol.27 , pp. 1564-1576
    • Sultana, R.1    Boyd-Kimball, D.2    Poon, H.F.3    Cai, J.4    Pierce, W.M.5    Klein, J.B.6    Merchant, M.7    Markesbery, W.R.8    Butterfield, D.A.9
  • 3
    • 0031980065 scopus 로고    scopus 로고
    • Four-hydroxynonenal, A product of lipid peroxidation, is increased in the brain in Alzheimer's disease
    • Markesbery WR, Lovell MA (1998) Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease. Neurobiol Aging 19, 33-36.
    • (1998) Neurobiol Aging , vol.19 , pp. 33-36
    • Markesbery, W.R.1    Lovell, M.A.2
  • 4
    • 33847378451 scopus 로고    scopus 로고
    • Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: Systematic review and meta-analysis
    • Bjelakovic G, Nikolova D, Gluud LL, Simonetti RG, Gluud C (2007) Mortality in randomized trials of antioxidant supplements for primary and secondary prevention: systematic review and meta-analysis. JAMA 297, 842-857.
    • (2007) JAMA , vol.297 , pp. 842-857
    • Bjelakovic, G.1    Nikolova, D.2    Gluud, L.L.3    Simonetti, R.G.4    Gluud, C.5
  • 8
    • 67650921433 scopus 로고    scopus 로고
    • Vitamin e paradox in Alzheimer's disease: It does not prevent loss of cognition and may even be detrimental
    • Lloret A, Badia MC, Mora NJ, Pallardo FV, Alonso MD, Vina J (2009) Vitamin E paradox in Alzheimer's disease: it does not prevent loss of cognition and may even be detrimental. J Alzheimers Dis 17, 143-149.
    • (2009) J Alzheimers Dis , vol.17 , pp. 143-149
    • Lloret, A.1    Badia, M.C.2    Mora, N.J.3    Pallardo, F.V.4    Alonso, M.D.5    Vina, J.6
  • 9
    • 0036372619 scopus 로고    scopus 로고
    • Redox potential of GSH/GSSG couple: Assay and biological significance
    • Jones DP (2002) Redox potential of GSH/GSSG couple: assay and biological significance. Methods Enzymol 348, 93-112.
    • (2002) Methods Enzymol , vol.348 , pp. 93-112
    • Jones, D.P.1
  • 10
    • 33744962865 scopus 로고    scopus 로고
    • Redefining oxidative stress
    • Jones DP (2006) Redefining oxidative stress. Antioxid Redox Signal 8, 1865-1879.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 1865-1879
    • Jones, D.P.1
  • 11
    • 33744949848 scopus 로고    scopus 로고
    • Extracellular redox state: Refining the definition of oxidative stress in aging
    • Jones DP (2006) Extracellular redox state: refining the definition of oxidative stress in aging. Rejuvenation Res 9, 169-181.
    • (2006) Rejuvenation Res , vol.9 , pp. 169-181
    • Jones, D.P.1
  • 15
    • 22544480331 scopus 로고    scopus 로고
    • Effect of antioxidant-enriched diets on glutathione redox status in tissue homogenates and mitochondria of the senescence-accelerated mouse
    • Rebrin I, Zicker S, Wedekind KJ, Paetau-Robinson I, Packer L, Sohal RS (2005) Effect of antioxidant-enriched diets on glutathione redox status in tissue homogenates and mitochondria of the senescence-accelerated mouse. Free Radic Biol Med 39, 549-557.
    • (2005) Free Radic Biol Med , vol.39 , pp. 549-557
    • Rebrin, I.1    Zicker, S.2    Wedekind, K.J.3    Paetau-Robinson, I.4    Packer, L.5    Sohal, R.S.6
  • 18
    • 75149195480 scopus 로고    scopus 로고
    • Age-related toxicity of β- Amyloid associated with increased pERK and pCREB in primary hippocampal neurons: Reversal by blueberry extract
    • in press
    • Brewer GJ, Lindsey AL, Kunz EZ, Torricelli JR, Neuman A, Fisher DR, Joseph JA (2009) Age-related toxicity of β- amyloid associated with increased pERK and pCREB in primary hippocampal neurons: reversal by blueberry extract. J Nutr Biochem, in press.
    • (2009) J Nutr Biochem
    • Brewer, G.J.1    Lindsey, A.L.2    Kunz, E.Z.3    Torricelli, J.R.4    Neuman, A.5    Fisher, D.R.6    Joseph, J.A.7
  • 19
    • 0027968491 scopus 로고
    • The DNA-binding efficiency of Sp1 is affected by redox changes
    • Ammendola R, Mesuraca M, Russo T, Cimino F (1994) The DNA-binding efficiency of Sp1 is affected by redox changes. Eur J Biochem 225, 483-489.
    • (1994) Eur J Biochem , vol.225 , pp. 483-489
    • Ammendola, R.1    Mesuraca, M.2    Russo, T.3    Cimino, F.4
  • 20
    • 0034859820 scopus 로고    scopus 로고
    • Oxidation of zinc finger transcription factors: Physiological consequences
    • Webster KA, Prentice H, Bishopric NH (2001) Oxidation of zinc finger transcription factors: physiological consequences. Antioxid Redox Signal 3, 535-548.
    • (2001) Antioxid Redox Signal , vol.3 , pp. 535-548
    • Webster, K.A.1    Prentice, H.2    Bishopric, N.H.3
  • 21
    • 34249104544 scopus 로고    scopus 로고
    • Oxidative stress and aberrant signaling in aging and cognitive decline
    • Droge W, Schipper HM (2007) Oxidative stress and aberrant signaling in aging and cognitive decline. Aging Cell 6, 361-370.
    • (2007) Aging Cell , vol.6 , pp. 361-370
    • Droge, W.1    Schipper, H.M.2
  • 22
    • 49849084827 scopus 로고    scopus 로고
    • Redox control of endothelial function and dysfunction: Molecular mechanisms and therapeutic opportunities
    • Thomas SR, Witting PK, Drummond GR (2008) Redox control of endothelial function and dysfunction: molecular mechanisms and therapeutic opportunities. Antioxid Redox Signal 10, 1713-1765.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 1713-1765
    • Thomas, S.R.1    Witting, P.K.2    Drummond, G.R.3
  • 23
    • 0037221433 scopus 로고    scopus 로고
    • Hydrogen peroxide modulation of synaptic plasticity
    • Kamsler A, Segal M (2003) Hydrogen peroxide modulation of synaptic plasticity. J Neurosci 23, 269-276.
    • (2003) J Neurosci , vol.23 , pp. 269-276
    • Kamsler, A.1    Segal, M.2
  • 24
    • 33846635882 scopus 로고    scopus 로고
    • High-throughput identification of catalytic redoxactive cysteine residues
    • Fomenko DE, Xing W, Adair BM, Thomas DJ, Gladyshev VN (2007) High-throughput identification of catalytic redoxactive cysteine residues. Science 315, 387-389.
    • (2007) Science , vol.315 , pp. 387-389
    • Fomenko, D.E.1    Xing, W.2    Adair, B.M.3    Thomas, D.J.4    Gladyshev, V.N.5
  • 25
    • 48249155387 scopus 로고    scopus 로고
    • Age-related decreases in NAD(P)H and glutathione cause redox declines before ATP loss during glutamate treatment of hippocampal neurons
    • Parihar MS, Kunz EA, Brewer GJ (2008) Age-related decreases in NAD(P)H and glutathione cause redox declines before ATP loss during glutamate treatment of hippocampal neurons. J Neurosci Res 86, 2339-2352.
    • (2008) J Neurosci Res , vol.86 , pp. 2339-2352
    • Parihar, M.S.1    Kunz, E.A.2    Brewer, G.J.3
  • 27
    • 34147219139 scopus 로고    scopus 로고
    • Simultaneous age-related depolarization of mitochondrial membrane potential and increased mitochondrial reactive oxygen species production correlate with age-related glutamate excitotoxicity in rat hippocampal neurons
    • Parihar MS, Brewer GJ (2007) Simultaneous age-related depolarization of mitochondrial membrane potential and increased mitochondrial reactive oxygen species production correlate with age-related glutamate excitotoxicity in rat hippocampal neurons. J Neurosci Res 85, 1018-1032.
    • (2007) J Neurosci Res , vol.85 , pp. 1018-1032
    • Parihar, M.S.1    Brewer, G.J.2
  • 28
    • 58149522903 scopus 로고    scopus 로고
    • Critical age-related loss of cofactors of neuron cytochrome C oxidase reversed by estrogen
    • Jones TT, Brewer GJ (2009) Critical age-related loss of cofactors of neuron cytochrome C oxidase reversed by estrogen. Exp Neurol 215, 212-219.
    • (2009) Exp Neurol , vol.215 , pp. 212-219
    • Jones, T.T.1    Brewer, G.J.2
  • 29
    • 62549117802 scopus 로고    scopus 로고
    • Altered redox balance in disease: Can we change the new equilibria?
    • Perry G, Zhu X, Moreira PI, Smith MA (2009) Altered redox balance in disease: can we change the new equilibria? Ann Neurol 65, 121-123.
    • (2009) Ann Neurol , vol.65 , pp. 121-123
    • Perry, G.1    Zhu, X.2    Moreira, P.I.3    Smith, M.A.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.