Hydrogen peroxide promotes Aβ production through JNK-dependent activation of γ-secretase

Journal of Biological Chemistry

Volumn 283, Issue 25, 2008, Pages 17721-17730

  Shen, Chengyong ^a   Chen, Yongfeng ^a   Liu, Huaqing ^a   Zhang, Kejing ^a   Zhang, Ting ^a   Lin, Anning ^b   Jing, Naihe ^a  

^a Shanghai Jiao Tong University Affiliated Sixth People s Hospital   (China)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; BRAIN; ENZYME ACTIVITY; GLYCOPROTEINS; HYDROGEN; HYDROGEN PEROXIDE; MATHEMATICAL MODELS; NUCLEIC ACIDS; PUMPING PLANTS; RNA;

ALZHEIMER DISEASES; AMYLOID PRECURSOR PROTEINS; HUMAN BRAINS; HUMAN NEUROBLASTOMA; SECRETASE; SENILE PLAQUES; TERMINAL KINASES; UNDERLYING MECHANISMS;

HYDROGEN PRODUCTION;

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; GAMMA SECRETASE; HYDROGEN PEROXIDE; STRESS ACTIVATED PROTEIN KINASE; ENZYME INHIBITOR; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; PROTEIN KINASE B; SECRETASE;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; HUMAN TISSUE; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SECRETION; PROTEIN SYNTHESIS; SENILE PLAQUE; AGED; ANIMAL; BIOLOGICAL MODEL; BRAIN; FEMALE; GENETICS; MALE; METABOLISM; PATHOLOGY;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; BRAIN; ENZYME INHIBITORS; FEMALE; HUMANS; HYDROGEN PEROXIDE; MALE; MAP KINASE KINASE 4; MICE; MODELS, BIOLOGICAL; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 47749147258     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M800013200     Document Type: Article

References (51)

1. Selkoe, D. J. (2002) Science 298, 789-791
2. Saido, T. C., and Iwata, N. (2006) Neurosci. Res. 54, 235-253
3. Funato, H., Yoshimura, M., Kusui, K., Tamaoka, A., Ishikawa, K., Ohkoshi, N., Namekata, K., Okeda, R., and Ihara, Y. (1998) Am. J. Pathol. 152, 1633-1640
4. Mattson, M. P. (2004) Nature 430, 631-639
5. Selkoe, D. J., and Wolfe, M. S. (2007) Cell 131, 215-221
6. Marjaux, E., Hartmann, D., and De Strooper, B. (2004) Neuron 42, 189-192
7. Shah, S., Lee, S. F., Tabuchi, K., Hao, Y. H., Yu, C., LaPlant, Q., Ball, H., Dann, C. E., 3rd, Sudhof, T., and Yu, G. (2005) Cell 122, 435-447
8. Wolfe, M. S., Xia, W., Ostaszewski, B. L., Diehl, T. S., Kimberly, W. T., and Selkoe, D. J. (1999) Nature 398, 513-517
9. Edbauer, D., Winkler, E., Regula, J. T., Pesold, B., Steiner, H., and Haass, C. (2003) Nat. Cell Biol. 5, 486-488
10. Koo, E. H., and Kopan, R. (2004) Nat. Med. 10, (suppl.) S26-S33
11. Finkel, T., and Holbrook, N. J. (2000) Nature 408, 239-247
12. Smith, M. A., Rottkamp, C. A., Nunomura, A., Raina, A. K., and Perry, G. (2000) Biochim. Biophys. Acta 1502, 139-144
13. Ono, K., Hamaguchi, T., Naiki, H., and Yamada, M. (2006) Biochim. Biophys. Acta 1762, 575-586
14. Tabner, B. J., El-Agnaf, O. M., Turnbull, S., German, M. J., Paleologou, K. E., Hayashi, Y., Cooper, L. J., Fullwood, N. J., and Allsop, D. (2005) J. Biol. Chem. 280, 35789-35792
15. Misonou, H., Morishima-Kawashima, M., and Ihara, Y. (2000) Biochemistry 39, 6951-6959
16. Frederikse, P. H., Garland, D., Zigler, J. S., Jr., and Piatigorsky, J. (1996) J. Biol. Chem. 271, 10169-10174
17. Tong, Y., Zhou, W., Fung, V., Christensen, M. A., Qing, H., Sun, X., and Song, W. (2005) J. Neural. Transm. 112, 455-469
18. Tamagno, E., Parola, M., Bardini, P., Piccini, A., Borghi, R., Guglielmotto, M., Santoro, G., Davit, A., Danni, O., Smith, M. A., Perry, G., and Tabaton, M. (2005) J. Neurochem. 92, 628-636
19. Sung, S., Yao, Y., Uryu, K., Yang, H., Lee, V. M., Trojanowski, J. Q., and Pratico, D. (2004) FASEB J. 18, 323-325
20. Tamagno, E., Bardini, P., Obbili, A., Vitali, A., Borghi, R., Zaccheo, D., Pronzato, M. A., Danni, O., Smith, M. A., Perry, G., and Tabaton, M. (2002) Neurobiol. Dis. 10, 279-288
21. Tang, K., Wang, C., Shen, C., Sheng, S., Ravid, R., and Jing, N. (2003) Eur. J. Neurosci. 18, 102-108
22. Karlstrom, H., Bergman, A., Lendahl, U., Naslund, J., and Lundkvist, J. (2002) J. Biol. Chem. 277, 6763-6766
23. Cheng, L., Jin, Z., Liu, L., Yan, Y., Li, T., Zhu, X., and Jing, N. (2004) FEBS Lett. 565, 195-202
24. Oleinik, N. V., Krupenko, N. I., and Krupenko, S. A. (2007) Oncogene 26, 7222-7230
25. Ermolieff, J., Loy, J. A., Koelsch, G., and Tang, J. (2000) Biochemistry 39, 12450-12456
26. Hsiao, K., Chapman, P., Nilsen, S., Eckman, C., Harigaya, Y., Younkin, S., Yang, F., and Cole, G. (1996) Science 274, 99-102
27. Rhee, S. G. (2006) Science 312, 1882-1883
28. Skovronsky, D. M., Moore, D. B., Milla, M. E., Doms, R. W., and Lee, V. M. (2000) J. Biol. Chem. 275, 2568-2575
29. Zhou, Y., Suram, A., Venugopal, C., Prakasam, A., Lin, S., Su, Y., Li, B., Paul, S. M., and Sambamurti, K. (2008) FASEB J. 22, 47-54
30. Kimberly, W. T., Zheng, J. B., Guenette, S. Y., and Selkoe, D. J. (2001) J. Biol. Chem. 276, 40288-40292
31. Ni, Y., Zhao, X., Bao, G., Zou, L., Teng, L., Wang, Z., Song, M., Xiong, J., Bai, Y., and Pei, G. (2006) Nat. Med. 12, 1390-1396
32. Liu, J., and Lin, A. (2005) Cell Res. 15, 36-42
33. Vingtdeux, V., Hamdane, M., Gompel, M., Begard, S., Drobecq, H., Ghestem, A., Grosjean, M. E., Kostanjevecki, V., Grognet, P., Vanmechelen, E., Buee, L., Delacourte, A., and Sergeant, N. (2005) Neurobiol. Dis. 20, 625-637
34. Lee, M. S., Kao, S. C., Lemere, C. A., Xia, W., Tseng, H. C., Zhou, Y., Neve, R., Ahlijanian, M. K., and Tsai, L. H. (2003) J. Cell Biol. 163, 83-95
35. Ruffels, J., Griffin, M., and Dickenson, J. M. (2004) Eur. J. Pharmacol. 483, 163-173
36. Zhu, X., Raina, A. K., Rottkamp, C. A., Aliev, G., Perry, G., Boux, H., and Smith, M. A. (2001) J. Neurochem. 76, 435-441
37. Swatton, J. E., Sellers, L. A., Faull, R. L., Holland, A., Iritani, S., and Bahn, S. (2004) Eur. J. Neurosci. 19, 2711-2719
38. Hartzell, H. C. (2007) Science 317, 1331-1332
39. Beckman, K. B., and Ames, B. N. (1998) Physiol. Rev. 78, 547-581
40. Babior, B. M., Kipnes, R. S., and Curnutte, J. T. (1973) J. Clin. Investig. 52, 741-744
41. Li, J. M., Mullen, A. M., Yun, S., Wientjes, F., Brouns, G. Y., Thrasher, A. J., and Shah, A. M. (2002) Circ. Res. 90, 143-150
42. Schallreuter, K. U., Moore, J., Wood, J. M., Beazley, W. D., Gaze, D. C., Tobin, D. J., Marshall, H. S., Panske, A., Panzig, E., and Hibberts, N. A. (1999) J. Investig. Dermatol. Symp. Proc. 4, 91-96
43. Schallreuter, K. U., Moore, J., Wood, J. M., Beazley, W. D., Peters, E. M., Marles, L. K., Behrens-Williams, S. C., Dummer, R., Blau, N., and Thony, B. (2001) J. Investig. Dermatol. 116, 167-174
44. Benzing, W. C., Wujek, J. R., Ward, E. K., Shaffer, D., Ashe, K. H., Younkin, S. G., and Brunden, K. R. (1999) Neurobiol. Aging 20, 581-589
45. Liao, Y. F., Wang, B. J., Cheng, H. T., Kuo, L. H., and Wolfe, M. S. (2004) J. Biol. Chem. 279, 49523-49532
46. Zhang, S., Lin, Y., Kim, Y. S., Hande, M. P., Liu, Z. G., and Shen, H. M. (2007) Cell Death Differ. 14, 1001-1010
47. McLendon, C., Xin, T., Ziani-Cherif, C., Murphy, M. P., Findlay, K. A., Lewis, P. A., Pinnix, I., Sambamurti, K., Wang, R., Fauq, A., and Golde, T. E. (2000) FASEB J. 14, 2383-2386
48. Jin, S. M., Cho, H. J., Jung, M. W., and Mook-Jung, I. (2007) Cell Death Differ. 14, 189-192
49. Xie, Z., Dong, Y., Maeda, U., Moir, R. D., Xia, W., Culley, D. J., Crosby, G., and Tanzi, R. E. (2007) J. Neurosci. 27, 1247-1254
50. Tamagno, E., Guglielmotto, M., Aragno, M., Borghi, R., Autelli, R., Giliberto, L., Muraca, G., Danni, O., Zhu, X., Smith, M. A., Perry, G., Jo, D. G., Mattson, M. P., and Tabaton, M. (2008) J. Neurochem. 104, 683- 695
51. Zhu, X., Raina, A. K., Perry, G., and Smith, M. A. (2004) Lancet. Neurol. 3, 219-226