-
1
-
-
0345490853
-
A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease
-
Abbas N., Lucking C.B., Ricard S., Durr A., Bonifati V., De Michele G., Bouley S., Vaughan J.R., Gasser T., Marconi R., Broussolle E., Brefel-Courbon C., Harhangi B.S., Oostra B.A., Fabrizio E., Bohme G.A., Pradier L., Wood N.W., Filla A., Meco G., Denefle P., Agid Y., Brice A. A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease. Human Molecular Genetics 1999, 8:567-574.
-
(1999)
Human Molecular Genetics
, vol.8
, pp. 567-574
-
-
Abbas, N.1
Lucking, C.B.2
Ricard, S.3
Durr, A.4
Bonifati, V.5
De Michele, G.6
Bouley, S.7
Vaughan, J.R.8
Gasser, T.9
Marconi, R.10
Broussolle, E.11
Brefel-Courbon, C.12
Harhangi, B.S.13
Oostra, B.A.14
Fabrizio, E.15
Bohme, G.A.16
Pradier, L.17
Wood, N.W.18
Filla, A.19
Meco, G.20
Denefle, P.21
Agid, Y.22
Brice, A.23
more..
-
2
-
-
78349309594
-
Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects
-
Amo T., Sato S., Saiki S., Wolf A.M., Toyomizu M., Gautier C.A., Shen J., Ohta S., Hattori N. Mitochondrial membrane potential decrease caused by loss of PINK1 is not due to proton leak, but to respiratory chain defects. Neurobiology of Disease 2011, 41:111-118.
-
(2011)
Neurobiology of Disease
, vol.41
, pp. 111-118
-
-
Amo, T.1
Sato, S.2
Saiki, S.3
Wolf, A.M.4
Toyomizu, M.5
Gautier, C.A.6
Shen, J.7
Ohta, S.8
Hattori, N.9
-
3
-
-
33846115045
-
Anonymous A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease
-
Anonymous A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease. Neurology 2007, 68:20-28.
-
(2007)
Neurology
, vol.68
, pp. 20-28
-
-
-
4
-
-
77957351763
-
Variations of the CAG trinucleotide repeat in DNA polymerase gamma (POLG1) is associated with Parkinson's disease in Sweden
-
Anvret A., Westerlund M., Sydow O., Willows T., Lind C., Galter D., Belin A.C. Variations of the CAG trinucleotide repeat in DNA polymerase gamma (POLG1) is associated with Parkinson's disease in Sweden. Neuroscience Letters 2010, 485:117-120.
-
(2010)
Neuroscience Letters
, vol.485
, pp. 117-120
-
-
Anvret, A.1
Westerlund, M.2
Sydow, O.3
Willows, T.4
Lind, C.5
Galter, D.6
Belin, A.C.7
-
5
-
-
58249124989
-
Analysis of targeted mutation in DJ-1 on cellular function in primary astrocytes
-
Ashley A.K., Hanneman W.H., Katoh T., Moreno J.A., Pollack A., Tjalkens R.B., Legare M.E. Analysis of targeted mutation in DJ-1 on cellular function in primary astrocytes. Toxicology Letters 2009, 184:186-191.
-
(2009)
Toxicology Letters
, vol.184
, pp. 186-191
-
-
Ashley, A.K.1
Hanneman, W.H.2
Katoh, T.3
Moreno, J.A.4
Pollack, A.5
Tjalkens, R.B.6
Legare, M.E.7
-
6
-
-
7444270637
-
Modulation of antioxidant defense systems by the environmental pesticide maneb in dopaminergic cells
-
Barlow B.K., Lee D.W., Cory-Slechta D.A., Opanashuk L.A. Modulation of antioxidant defense systems by the environmental pesticide maneb in dopaminergic cells. Neurotoxicology 2005, 26:63-75.
-
(2005)
Neurotoxicology
, vol.26
, pp. 63-75
-
-
Barlow, B.K.1
Lee, D.W.2
Cory-Slechta, D.A.3
Opanashuk, L.A.4
-
7
-
-
0038051345
-
Mitochondria, oxidative damage, and inflammation in Parkinson's disease
-
Beal M.F. Mitochondria, oxidative damage, and inflammation in Parkinson's disease. Annals of the New York Academy of Sciences 2003, 991:120-131.
-
(2003)
Annals of the New York Academy of Sciences
, vol.991
, pp. 120-131
-
-
Beal, M.F.1
-
8
-
-
64649093555
-
Mitochondrial fusion and division: regulation and role in cell viability
-
Benard G., Karbowski M. Mitochondrial fusion and division: regulation and role in cell viability. Seminars in Cell & Developmental Biology 2009, 20:365-374.
-
(2009)
Seminars in Cell & Developmental Biology
, vol.20
, pp. 365-374
-
-
Benard, G.1
Karbowski, M.2
-
9
-
-
33749835508
-
Creatine supplementation in Parkinson disease: a placebo-controlled randomized pilot trial
-
Bender A., Koch W., Elstner M., Schombacher Y., Bender J., Moeschl M., Gekeler F., Muller-Myhsok B., Gasser T., Tatsch K., Klopstock T. Creatine supplementation in Parkinson disease: a placebo-controlled randomized pilot trial. Neurology 2006, 67:1262-1264.
-
(2006)
Neurology
, vol.67
, pp. 1262-1264
-
-
Bender, A.1
Koch, W.2
Elstner, M.3
Schombacher, Y.4
Bender, J.5
Moeschl, M.6
Gekeler, F.7
Muller-Myhsok, B.8
Gasser, T.9
Tatsch, K.10
Klopstock, T.11
-
10
-
-
33646375711
-
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
-
Bender A., Krishnan K.J., Morris C.M., Taylor G.A., Reeve A.K., Perry R.H., Jaros E., Hersheson J.S., Betts J., Klopstock T., Taylor R.W., Turnbull D.M. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease. Nature Genetics 2006, 38:515-517.
-
(2006)
Nature Genetics
, vol.38
, pp. 515-517
-
-
Bender, A.1
Krishnan, K.J.2
Morris, C.M.3
Taylor, G.A.4
Reeve, A.K.5
Perry, R.H.6
Jaros, E.7
Hersheson, J.S.8
Betts, J.9
Klopstock, T.10
Taylor, R.W.11
Turnbull, D.M.12
-
11
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet R., Sherer T.B., MacKenzie G., Garcia-Osuna M., Panov A.V., Greenamyre J.T. Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nature Neuroscience 2000, 3:1301-1306.
-
(2000)
Nature Neuroscience
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
12
-
-
84863104152
-
Overexpression of parkin ameliorates dopaminergic neurodegeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice
-
Bian M., Liu J., Hong X., Yu M., Huang Y., Sheng Z., Fei J., Huang F. Overexpression of parkin ameliorates dopaminergic neurodegeneration induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. PloS One 2012, 7:e39953.
-
(2012)
PloS One
, vol.7
-
-
Bian, M.1
Liu, J.2
Hong, X.3
Yu, M.4
Huang, Y.5
Sheng, Z.6
Fei, J.7
Huang, F.8
-
13
-
-
68949125734
-
Zeroing in on LRRK2-linked pathogenic mechanisms in Parkinson's disease
-
Biskup S., West A.B. Zeroing in on LRRK2-linked pathogenic mechanisms in Parkinson's disease. Biochimica et Biophysica Acta 2009, 1792:625-633.
-
(2009)
Biochimica et Biophysica Acta
, vol.1792
, pp. 625-633
-
-
Biskup, S.1
West, A.B.2
-
14
-
-
33845298032
-
Localization of LRRK2 to membranous and vesicular structures in mammalian brain
-
Biskup S., Moore D.J., Celsi F., Higashi S., West A.B., Andrabi S.A., Kurkinen K., Yu S.W., Savitt J.M., Waldvogel H.J., Faull R.L., Emson P.C., Torp R., Ottersen O.P., Dawson T.M., Dawson V.L. Localization of LRRK2 to membranous and vesicular structures in mammalian brain. Annals of Neurology 2006, 60:557-569.
-
(2006)
Annals of Neurology
, vol.60
, pp. 557-569
-
-
Biskup, S.1
Moore, D.J.2
Celsi, F.3
Higashi, S.4
West, A.B.5
Andrabi, S.A.6
Kurkinen, K.7
Yu, S.W.8
Savitt, J.M.9
Waldvogel, H.J.10
Faull, R.L.11
Emson, P.C.12
Torp, R.13
Ottersen, O.P.14
Dawson, T.M.15
Dawson, V.L.16
-
15
-
-
65249159732
-
Formation of a stabilized cysteine sulfinic acid is critical for the mitochondrial function of the parkinsonism protein DJ-1
-
Blackinton J., Lakshminarasimhan M., Thomas K.J., Ahmad R., Greggio E., Raza A.S., Cookson M.R., Wilson M.A. Formation of a stabilized cysteine sulfinic acid is critical for the mitochondrial function of the parkinsonism protein DJ-1. The Journal of Biological Chemistry 2009, 284:6476-6485.
-
(2009)
The Journal of Biological Chemistry
, vol.284
, pp. 6476-6485
-
-
Blackinton, J.1
Lakshminarasimhan, M.2
Thomas, K.J.3
Ahmad, R.4
Greggio, E.5
Raza, A.S.6
Cookson, M.R.7
Wilson, M.A.8
-
16
-
-
0027971104
-
Mitochondrial respiratory failure in skeletal muscle from patients with Parkinson's disease and multiple system atrophy
-
Blin O., Desnuelle C., Rascol O., Borg M., Peyro Saint Paul H., Azulay J.P., Bille F., Figarella D., Coulom F., Pellissier J.F., et al. Mitochondrial respiratory failure in skeletal muscle from patients with Parkinson's disease and multiple system atrophy. Journal of the Neurological Sciences 1994, 125:95-101.
-
(1994)
Journal of the Neurological Sciences
, vol.125
, pp. 95-101
-
-
Blin, O.1
Desnuelle, C.2
Rascol, O.3
Borg, M.4
Peyro Saint Paul, H.5
Azulay, J.P.6
Bille, F.7
Figarella, D.8
Coulom, F.9
Pellissier, J.F.10
-
17
-
-
0032171185
-
L-type calcium channels mediate a slow excitatory synaptic transmission in rat midbrain dopaminergic neurons
-
Bonci A., Grillner P., Mercuri N.B., Bernardi G. L-type calcium channels mediate a slow excitatory synaptic transmission in rat midbrain dopaminergic neurons. The Journal of Neuroscience: the Official Journal of the Society for Neuroscience 1998, 18:6693-6703.
-
(1998)
The Journal of Neuroscience: the Official Journal of the Society for Neuroscience
, vol.18
, pp. 6693-6703
-
-
Bonci, A.1
Grillner, P.2
Mercuri, N.B.3
Bernardi, G.4
-
18
-
-
0037428241
-
Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
-
Bonifati V., Rizzu P., van Baren M.J., Schaap O., Breedveld G.J., Krieger E., Dekker M.C., Squitieri F., Ibanez P., Joosse M., van Dongen J.W., Vanacore N., van Swieten J.C., Brice A., Meco G., van Duijn C.M., Oostra B.A., Heutink P. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science 2003, 299:256-259.
-
(2003)
Science
, vol.299
, pp. 256-259
-
-
Bonifati, V.1
Rizzu, P.2
van Baren, M.J.3
Schaap, O.4
Breedveld, G.J.5
Krieger, E.6
Dekker, M.C.7
Squitieri, F.8
Ibanez, P.9
Joosse, M.10
van Dongen, J.W.11
Vanacore, N.12
van Swieten, J.C.13
Brice, A.14
Meco, G.15
van Duijn, C.M.16
Oostra, B.A.17
Heutink, P.18
-
19
-
-
0033608811
-
Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss
-
Brooks A.I., Chadwick C.A., Gelbard H.A., Cory-Slechta D.A., Federoff H.J. Paraquat elicited neurobehavioral syndrome caused by dopaminergic neuron loss. Brain Research 1999, 823:1-10.
-
(1999)
Brain Research
, vol.823
, pp. 1-10
-
-
Brooks, A.I.1
Chadwick, C.A.2
Gelbard, H.A.3
Cory-Slechta, D.A.4
Federoff, H.J.5
-
20
-
-
79953685935
-
Alterations in the mitochondrial proteome of neuroblastoma cells in response to complex 1 inhibition
-
Burte F., De Girolamo L.A., Hargreaves A.J., Billett E.E. Alterations in the mitochondrial proteome of neuroblastoma cells in response to complex 1 inhibition. Journal of Proteome Research 2011, 10:1974-1986.
-
(2011)
Journal of Proteome Research
, vol.10
, pp. 1974-1986
-
-
Burte, F.1
De Girolamo, L.A.2
Hargreaves, A.J.3
Billett, E.E.4
-
21
-
-
84859169870
-
The mitochondrial chaperone protein TRAP1 mitigates alpha-Synuclein toxicity
-
Butler E.K., Voigt A., Lutz A.K., Toegel J.P., Gerhardt E., Karsten P., Falkenburger B., Reinartz A., Winklhofer K.F., Schulz J.B. The mitochondrial chaperone protein TRAP1 mitigates alpha-Synuclein toxicity. PLoS Genetics 2012, 8:e1002488.
-
(2012)
PLoS Genetics
, vol.8
-
-
Butler, E.K.1
Voigt, A.2
Lutz, A.K.3
Toegel, J.P.4
Gerhardt, E.5
Karsten, P.6
Falkenburger, B.7
Reinartz, A.8
Winklhofer, K.F.9
Schulz, J.B.10
-
22
-
-
2942684871
-
The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization
-
Canet-Aviles R.M., Wilson M.A., Miller D.W., Ahmad R., McLendon C., Bandyopadhyay S., Baptista M.J., Ringe D., Petsko G.A., Cookson M.R. The Parkinson's disease protein DJ-1 is neuroprotective due to cysteine-sulfinic acid-driven mitochondrial localization. Proceedings of the National Academy of Sciences of the United States of America 2004, 101:9103-9108.
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, pp. 9103-9108
-
-
Canet-Aviles, R.M.1
Wilson, M.A.2
Miller, D.W.3
Ahmad, R.4
McLendon, C.5
Bandyopadhyay, S.6
Baptista, M.J.7
Ringe, D.8
Petsko, G.A.9
Cookson, M.R.10
-
23
-
-
84860223145
-
Mitochondrial metabolic control of microtubule dynamics impairs the autophagic pathway in Parkinson's disease
-
Cardoso S.M., Esteves A.R., Arduino D.M. Mitochondrial metabolic control of microtubule dynamics impairs the autophagic pathway in Parkinson's disease. Neuro-Degenerative Diseases 2012, 10:38-40.
-
(2012)
Neuro-Degenerative Diseases
, vol.10
, pp. 38-40
-
-
Cardoso, S.M.1
Esteves, A.R.2
Arduino, D.M.3
-
24
-
-
33646114508
-
Susceptibility to rotenone is increased in neurons from parkin null mice and is reduced by minocycline
-
Casarejos M.J., Menendez J., Solano R.M., Rodriguez-Navarro J.A., Garcia de Yebenes J., Mena M.A. Susceptibility to rotenone is increased in neurons from parkin null mice and is reduced by minocycline. Journal of Neurochemistry 2006, 97:934-946.
-
(2006)
Journal of Neurochemistry
, vol.97
, pp. 934-946
-
-
Casarejos, M.J.1
Menendez, J.2
Solano, R.M.3
Rodriguez-Navarro, J.A.4
Garcia de Yebenes, J.5
Mena, M.A.6
-
25
-
-
0025945089
-
Rapid ATP loss caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse brain
-
Chan P., DeLanney L.E., Irwin I., Langston J.W., Di Monte D. Rapid ATP loss caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mouse brain. Journal of Neurochemistry 1991, 57:348-351.
-
(1991)
Journal of Neurochemistry
, vol.57
, pp. 348-351
-
-
Chan, P.1
DeLanney, L.E.2
Irwin, I.3
Langston, J.W.4
Di Monte, D.5
-
26
-
-
34347359673
-
'Rejuvenation' protects neurons in mouse models of Parkinson's disease
-
Chan C.S., Guzman J.N., Ilijic E., Mercer J.N., Rick C., Tkatch T., Meredith G.E., Surmeier D.J. 'Rejuvenation' protects neurons in mouse models of Parkinson's disease. Nature 2007, 447:1081-1086.
-
(2007)
Nature
, vol.447
, pp. 1081-1086
-
-
Chan, C.S.1
Guzman, J.N.2
Ilijic, E.3
Mercer, J.N.4
Rick, C.5
Tkatch, T.6
Meredith, G.E.7
Surmeier, D.J.8
-
27
-
-
77951096150
-
Mitochondrial dynamics - fusion, fission, movement, and mitophagy - in neurodegenerative diseases
-
Chen H., Chan D.C. Mitochondrial dynamics - fusion, fission, movement, and mitophagy - in neurodegenerative diseases. Human Molecular Genetics 2009, 18:R169-R176.
-
(2009)
Human Molecular Genetics
, vol.18
-
-
Chen, H.1
Chan, D.C.2
-
28
-
-
20444367300
-
Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice
-
Chen L., Cagniard B., Mathews T., Jones S., Koh H.C., Ding Y., Carvey P.M., Ling Z., Kang U.J., Zhuang X. Age-dependent motor deficits and dopaminergic dysfunction in DJ-1 null mice. The Journal of Biological Chemistry 2005, 280:21418-21426.
-
(2005)
The Journal of Biological Chemistry
, vol.280
, pp. 21418-21426
-
-
Chen, L.1
Cagniard, B.2
Mathews, T.3
Jones, S.4
Koh, H.C.5
Ding, Y.6
Carvey, P.M.7
Ling, Z.8
Kang, U.J.9
Zhuang, X.10
-
29
-
-
84859712842
-
A progressive mouse model of Parkinson's disease: the Thy1-aSyn ("Line 61") mice
-
Chesselet M.F., Richter F., Zhu C., Magen I., Watson M.B., Subramaniam S.R. A progressive mouse model of Parkinson's disease: the Thy1-aSyn ("Line 61") mice. Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics 2012, 9:297-314.
-
(2012)
Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
, vol.9
, pp. 297-314
-
-
Chesselet, M.F.1
Richter, F.2
Zhu, C.3
Magen, I.4
Watson, M.B.5
Subramaniam, S.R.6
-
31
-
-
0021259475
-
Neurochemical and behavioral effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in rat, guinea pig, and monkey
-
Chiueh C.C., Markey S.P., Burns R.S., Johannessen J.N., Jacobowitz D.M., Kopin I.J. Neurochemical and behavioral effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in rat, guinea pig, and monkey. Psychopharmacology Bulletin 1984, 20:548-553.
-
(1984)
Psychopharmacology Bulletin
, vol.20
, pp. 548-553
-
-
Chiueh, C.C.1
Markey, S.P.2
Burns, R.S.3
Johannessen, J.N.4
Jacobowitz, D.M.5
Kopin, I.J.6
-
32
-
-
54449089025
-
Mitochondrial complex I inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat
-
Choi W.S., Kruse S.E., Palmiter R.D., Xia Z. Mitochondrial complex I inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat. Proceedings of the National Academy of Sciences of the United States of America 2008, 105:15136-15141.
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, pp. 15136-15141
-
-
Choi, W.S.1
Kruse, S.E.2
Palmiter, R.D.3
Xia, Z.4
-
33
-
-
33745589773
-
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
-
Clark I.E., Dodson M.W., Jiang C., Cao J.H., Huh J.R., Seol J.H., Yoo S.J., Hay B.A., Guo M. Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin. Nature 2006, 441:1162-1166.
-
(2006)
Nature
, vol.441
, pp. 1162-1166
-
-
Clark, I.E.1
Dodson, M.W.2
Jiang, C.3
Cao, J.H.4
Huh, J.R.5
Seol, J.H.6
Yoo, S.J.7
Hay, B.A.8
Guo, M.9
-
34
-
-
38349105900
-
Complex I is the major site of mitochondrial superoxide production by paraquat
-
Cocheme H.M., Murphy M.P. Complex I is the major site of mitochondrial superoxide production by paraquat. The Journal of Biological Chemistry 2008, 283:1786-1798.
-
(2008)
The Journal of Biological Chemistry
, vol.283
, pp. 1786-1798
-
-
Cocheme, H.M.1
Murphy, M.P.2
-
35
-
-
44749085250
-
Mitochondrial translocation of alpha-synuclein is promoted by intracellular acidification
-
Cole N.B., Dieuliis D., Leo P., Mitchell D.C., Nussbaum R.L. Mitochondrial translocation of alpha-synuclein is promoted by intracellular acidification. Experimental Cell Research 2008, 314:2076-2089.
-
(2008)
Experimental Cell Research
, vol.314
, pp. 2076-2089
-
-
Cole, N.B.1
Dieuliis, D.2
Leo, P.3
Mitchell, D.C.4
Nussbaum, R.L.5
-
36
-
-
0031787871
-
Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease
-
Conway K.A., Harper J.D., Lansbury P.T. Accelerated in vitro fibril formation by a mutant alpha-synuclein linked to early-onset Parkinson disease. Nature Medicine 1998, 4:1318-1320.
-
(1998)
Nature Medicine
, vol.4
, pp. 1318-1320
-
-
Conway, K.A.1
Harper, J.D.2
Lansbury, P.T.3
-
37
-
-
0034681163
-
Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy
-
Conway K.A., Lee S.J., Rochet J.C., Ding T.T., Williamson R.E., Lansbury P.T. Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy. Proceedings of the National Academy of Sciences of the United States of America 2000, 97:571-576.
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, pp. 571-576
-
-
Conway, K.A.1
Lee, S.J.2
Rochet, J.C.3
Ding, T.T.4
Williamson, R.E.5
Lansbury, P.T.6
-
38
-
-
37649004547
-
Cell systems and the toxic mechanism(s) of alpha-synuclein
-
Cookson M.R., van der Brug M. Cell systems and the toxic mechanism(s) of alpha-synuclein. Experimental Neurology 2008, 209:5-11.
-
(2008)
Experimental Neurology
, vol.209
, pp. 5-11
-
-
Cookson, M.R.1
van der Brug, M.2
-
39
-
-
63649095770
-
Parkinson's disease and residential exposure to maneb and paraquat from agricultural applications in the central valley of California
-
Costello S., Cockburn M., Bronstein J., Zhang X., Ritz B. Parkinson's disease and residential exposure to maneb and paraquat from agricultural applications in the central valley of California. American Journal of Epidemiology 2009, 169:919-926.
-
(2009)
American Journal of Epidemiology
, vol.169
, pp. 919-926
-
-
Costello, S.1
Cockburn, M.2
Bronstein, J.3
Zhang, X.4
Ritz, B.5
-
40
-
-
34147177574
-
Clinical research: testing a novel strategy against Parkinson's disease
-
Couzin J. Clinical research: testing a novel strategy against Parkinson's disease. Science 2007, 315:1778.
-
(2007)
Science
, vol.315
, pp. 1778
-
-
Couzin, J.1
-
41
-
-
0037338634
-
Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death
-
Darios F., Corti O., Lucking C.B., Hampe C., Muriel M.P., Abbas N., Gu W.J., Hirsch E.C., Rooney T., Ruberg M., Brice A. Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death. Human Molecular Genetics 2003, 12:517-526.
-
(2003)
Human Molecular Genetics
, vol.12
, pp. 517-526
-
-
Darios, F.1
Corti, O.2
Lucking, C.B.3
Hampe, C.4
Muriel, M.P.5
Abbas, N.6
Gu, W.J.7
Hirsch, E.C.8
Rooney, T.9
Ruberg, M.10
Brice, A.11
-
42
-
-
0141741347
-
Parkinson's disease: mechanisms and models
-
Dauer W., Przedborski S. Parkinson's disease: mechanisms and models. Neuron 2003, 39:889-909.
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
43
-
-
0018608356
-
Chronic Parkinsonism secondary to intravenous injection of meperidine analogues
-
Davis G.C., Williams A.C., Markey S.P., Ebert M.H., Caine E.D., Reichert C.M., Kopin I.J. Chronic Parkinsonism secondary to intravenous injection of meperidine analogues. Psychiatry Research 1979, 1:249-254.
-
(1979)
Psychiatry Research
, vol.1
, pp. 249-254
-
-
Davis, G.C.1
Williams, A.C.2
Markey, S.P.3
Ebert, M.H.4
Caine, E.D.5
Reichert, C.M.6
Kopin, I.J.7
-
44
-
-
33750354046
-
Parkin and defective ubiquitination in Parkinson's disease
-
Dawson T.M. Parkin and defective ubiquitination in Parkinson's disease. Journal of Neural Transmission 2006, 70(Suppl.):209-213.
-
(2006)
Journal of Neural Transmission
, vol.70
, Issue.SUPPL.
, pp. 209-213
-
-
Dawson, T.M.1
-
45
-
-
55749090654
-
The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila
-
Deng H., Dodson M.W., Huang H., Guo M. The Parkinson's disease genes pink1 and parkin promote mitochondrial fission and/or inhibit fusion in Drosophila. Proceedings of the National Academy of Sciences of the United States of America 2008, 105:14503-14508.
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, pp. 14503-14508
-
-
Deng, H.1
Dodson, M.W.2
Huang, H.3
Guo, M.4
-
46
-
-
0029964357
-
MPP(+)-induced neurotoxicity in mouse is age-dependent: evidenced by the selective inhibition of complexes of electron transport
-
Desai V.G., Feuers R.J., Hart R.W., Ali S.F. MPP(+)-induced neurotoxicity in mouse is age-dependent: evidenced by the selective inhibition of complexes of electron transport. Brain Research 1996, 715:1-8.
-
(1996)
Brain Research
, vol.715
, pp. 1-8
-
-
Desai, V.G.1
Feuers, R.J.2
Hart, R.W.3
Ali, S.F.4
-
47
-
-
44049099669
-
Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain
-
Devi L., Raghavendran V., Prabhu B.M., Avadhani N.G., Anandatheerthavarada H.K. Mitochondrial import and accumulation of alpha-synuclein impair complex I in human dopaminergic neuronal cultures and Parkinson disease brain. The Journal of Biological Chemistry 2008, 283:9089-9100.
-
(2008)
The Journal of Biological Chemistry
, vol.283
, pp. 9089-9100
-
-
Devi, L.1
Raghavendran, V.2
Prabhu, B.M.3
Avadhani, N.G.4
Anandatheerthavarada, H.K.5
-
48
-
-
80053173420
-
Brain region specific mitophagy capacity could contribute to selective neuronal vulnerability in Parkinson's disease
-
Diedrich M., Kitada T., Nebrich G., Koppelstaetter A., Shen J., Zabel C., Klose J., Mao L. Brain region specific mitophagy capacity could contribute to selective neuronal vulnerability in Parkinson's disease. Proteome Science 2011, 9:59.
-
(2011)
Proteome Science
, vol.9
, pp. 59
-
-
Diedrich, M.1
Kitada, T.2
Nebrich, G.3
Koppelstaetter, A.4
Shen, J.5
Zabel, C.6
Klose, J.7
Mao, L.8
-
49
-
-
33747191688
-
Acute neurotoxic effects of mancozeb and maneb in mesencephalic neuronal cultures are associated with mitochondrial dysfunction
-
Domico L.M., Zeevalk G.D., Bernard L.P., Cooper K.R. Acute neurotoxic effects of mancozeb and maneb in mesencephalic neuronal cultures are associated with mitochondrial dysfunction. Neurotoxicology 2006, 27:816-825.
-
(2006)
Neurotoxicology
, vol.27
, pp. 816-825
-
-
Domico, L.M.1
Zeevalk, G.D.2
Bernard, L.P.3
Cooper, K.R.4
-
50
-
-
20444450523
-
Alpha-synuclein and parkin contribute to the assembly of ubiquitin lysine 63-linked multiubiquitin chains
-
Doss-Pepe E.W., Chen L., Madura K. Alpha-synuclein and parkin contribute to the assembly of ubiquitin lysine 63-linked multiubiquitin chains. The Journal of Biological Chemistry 2005, 280:16619-16624.
-
(2005)
The Journal of Biological Chemistry
, vol.280
, pp. 16619-16624
-
-
Doss-Pepe, E.W.1
Chen, L.2
Madura, K.3
-
51
-
-
77951185469
-
Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease
-
Edwards T.L., Scott W.K., Almonte C., Burt A., Powell E.H., Beecham G.W., Wang L., Zuchner S., Konidari I., Wang G., Singer C., Nahab F., Scott B., Stajich J.M., Pericak-Vance M., Haines J., Vance J.M., Martin E.R. Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease. Annals of Human Genetics 2010, 74:97-109.
-
(2010)
Annals of Human Genetics
, vol.74
, pp. 97-109
-
-
Edwards, T.L.1
Scott, W.K.2
Almonte, C.3
Burt, A.4
Powell, E.H.5
Beecham, G.W.6
Wang, L.7
Zuchner, S.8
Konidari, I.9
Wang, G.10
Singer, C.11
Nahab, F.12
Scott, B.13
Stajich, J.M.14
Pericak-Vance, M.15
Haines, J.16
Vance, J.M.17
Martin, E.R.18
-
52
-
-
33846636481
-
Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons
-
Ekstrand M.I., Terzioglu M., Galter D., Zhu S., Hofstetter C., Lindqvist E., Thams S., Bergstrand A., Hansson F.S., Trifunovic A., Hoffer B., Cullheim S., Mohammed A.H., Olson L., Larsson N.G. Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons. Proceedings of the National Academy of Sciences of the United States of America 2007, 104:1325-1330.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 1325-1330
-
-
Ekstrand, M.I.1
Terzioglu, M.2
Galter, D.3
Zhu, S.4
Hofstetter, C.5
Lindqvist, E.6
Thams, S.7
Bergstrand, A.8
Hansson, F.S.9
Trifunovic, A.10
Hoffer, B.11
Cullheim, S.12
Mohammed, A.H.13
Olson, L.14
Larsson, N.G.15
-
53
-
-
84867693278
-
Design innovations and baseline findings in a long-term Parkinson's trial: the National Institute of Neurological Disorders and Stroke Exploratory Trials in Parkinson's Disease Long-Term Study-1
-
Elm J.J. Design innovations and baseline findings in a long-term Parkinson's trial: the National Institute of Neurological Disorders and Stroke Exploratory Trials in Parkinson's Disease Long-Term Study-1. Movement Disorders:Official Journal of the Movement Disorder Society 2012, 27:1513-1521.
-
(2012)
Movement Disorders:Official Journal of the Movement Disorder Society
, vol.27
, pp. 1513-1521
-
-
Elm, J.J.1
-
54
-
-
36049038504
-
Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin
-
Exner N., Treske B., Paquet D., Holmstrom K., Schiesling C., Gispert S., Carballo-Carbajal I., Berg D., Hoepken H.H., Gasser T., Kruger R., Winklhofer K.F., Vogel F., Reichert A.S., Auburger G., Kahle P.J., Schmid B., Haass C. Loss-of-function of human PINK1 results in mitochondrial pathology and can be rescued by parkin. The Journal of Neuroscience:the Official Journal of the Society for Neuroscience 2007, 27:12413-12418.
-
(2007)
The Journal of Neuroscience:the Official Journal of the Society for Neuroscience
, vol.27
, pp. 12413-12418
-
-
Exner, N.1
Treske, B.2
Paquet, D.3
Holmstrom, K.4
Schiesling, C.5
Gispert, S.6
Carballo-Carbajal, I.7
Berg, D.8
Hoepken, H.H.9
Gasser, T.10
Kruger, R.11
Winklhofer, K.F.12
Vogel, F.13
Reichert, A.S.14
Auburger, G.15
Kahle, P.J.16
Schmid, B.17
Haass, C.18
-
56
-
-
33746594215
-
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling
-
Fallon L., Belanger C.M., Corera A.T., Kontogiannea M., Regan-Klapisz E., Moreau F., Voortman J., Haber M., Rouleau G., Thorarinsdottir T., Brice A., van Bergen En Henegouwen P.M., Fon E.A. A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling. Nature Cell Biology 2006, 8:834-842.
-
(2006)
Nature Cell Biology
, vol.8
, pp. 834-842
-
-
Fallon, L.1
Belanger, C.M.2
Corera, A.T.3
Kontogiannea, M.4
Regan-Klapisz, E.5
Moreau, F.6
Voortman, J.7
Haber, M.8
Rouleau, G.9
Thorarinsdottir, T.10
Brice, A.11
van Bergen En Henegouwen, P.M.12
Fon, E.A.13
-
57
-
-
0042922454
-
Clinical and genetic heterogeneity in progressive external ophthalmoplegia due to mutations in polymerase gamma
-
Filosto M., Mancuso M., Nishigaki Y., Pancrudo J., Harati Y., Gooch C., Mankodi A., Bayne L., Bonilla E., Shanske S., Hirano M., DiMauro S. Clinical and genetic heterogeneity in progressive external ophthalmoplegia due to mutations in polymerase gamma. Archives of Neurology 2003, 60:1279-1284.
-
(2003)
Archives of Neurology
, vol.60
, pp. 1279-1284
-
-
Filosto, M.1
Mancuso, M.2
Nishigaki, Y.3
Pancrudo, J.4
Harati, Y.5
Gooch, C.6
Mankodi, A.7
Bayne, L.8
Bonilla, E.9
Shanske, S.10
Hirano, M.11
DiMauro, S.12
-
58
-
-
7044270767
-
Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein
-
Fleming S.M., Salcedo J., Fernagut P.O., Rockenstein E., Masliah E., Levine M.S., Chesselet M.F. Early and progressive sensorimotor anomalies in mice overexpressing wild-type human alpha-synuclein. The Journal of Neuroscience: the Official Journal of the Society for Neuroscience 2004, 24:9434-9440.
-
(2004)
The Journal of Neuroscience: the Official Journal of the Society for Neuroscience
, vol.24
, pp. 9434-9440
-
-
Fleming, S.M.1
Salcedo, J.2
Fernagut, P.O.3
Rockenstein, E.4
Masliah, E.5
Levine, M.S.6
Chesselet, M.F.7
-
59
-
-
20044385568
-
Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein
-
Fornai F., Schluter O.M., Lenzi P., Gesi M., Ruffoli R., Ferrucci M., Lazzeri G., Busceti C.L., Pontarelli F., Battaglia G., Pellegrini A., Nicoletti F., Ruggieri S., Paparelli A., Sudhof T.C. Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein. Proceedings of the National Academy of Sciences of the United States of America 2005, 102:3413-3418.
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, pp. 3413-3418
-
-
Fornai, F.1
Schluter, O.M.2
Lenzi, P.3
Gesi, M.4
Ruffoli, R.5
Ferrucci, M.6
Lazzeri, G.7
Busceti, C.L.8
Pontarelli, F.9
Battaglia, G.10
Pellegrini, A.11
Nicoletti, F.12
Ruggieri, S.13
Paparelli, A.14
Sudhof, T.C.15
-
60
-
-
0027343340
-
Similarities and differences between MPTP-induced parkinsonsim and Parkinson's disease. Neuropathologic considerations
-
Forno L.S., DeLanney L.E., Irwin I., Langston J.W. Similarities and differences between MPTP-induced parkinsonsim and Parkinson's disease. Neuropathologic considerations. Advances in Neurology 1993, 60:600-608.
-
(1993)
Advances in Neurology
, vol.60
, pp. 600-608
-
-
Forno, L.S.1
DeLanney, L.E.2
Irwin, I.3
Langston, J.W.4
-
61
-
-
34250796802
-
The impact of the E46K mutation on the properties of alpha-synuclein in its monomeric and oligomeric states
-
Fredenburg R.A., Rospigliosi C., Meray R.K., Kessler J.C., Lashuel H.A., Eliezer D., Lansbury P.T. The impact of the E46K mutation on the properties of alpha-synuclein in its monomeric and oligomeric states. Biochemistry 2007, 46:7107-7118.
-
(2007)
Biochemistry
, vol.46
, pp. 7107-7118
-
-
Fredenburg, R.A.1
Rospigliosi, C.2
Meray, R.K.3
Kessler, J.C.4
Lashuel, H.A.5
Eliezer, D.6
Lansbury, P.T.7
-
62
-
-
33745087689
-
PINK1 protein in normal human brain and Parkinson's disease
-
Gandhi S., Muqit M.M., Stanyer L., Healy D.G., Abou-Sleiman P.M., Hargreaves I., Heales S., Ganguly M., Parsons L., Lees A.J., Latchman D.S., Holton J.L., Wood N.W., Revesz T. PINK1 protein in normal human brain and Parkinson's disease. Brain: a Journal of Neurology 2006, 129:1720-1731.
-
(2006)
Brain: a Journal of Neurology
, vol.129
, pp. 1720-1731
-
-
Gandhi, S.1
Muqit, M.M.2
Stanyer, L.3
Healy, D.G.4
Abou-Sleiman, P.M.5
Hargreaves, I.6
Heales, S.7
Ganguly, M.8
Parsons, L.9
Lees, A.J.10
Latchman, D.S.11
Holton, J.L.12
Wood, N.W.13
Revesz, T.14
-
63
-
-
65549124540
-
Leucine-rich repeat kinase 2 (LRRK2): a key player in the pathogenesis of Parkinson's disease
-
Gandhi P.N., Chen S.G., Wilson-Delfosse A.L. Leucine-rich repeat kinase 2 (LRRK2): a key player in the pathogenesis of Parkinson's disease. Journal of Neuroscience Research 2009, 87:1283-1295.
-
(2009)
Journal of Neuroscience Research
, vol.87
, pp. 1283-1295
-
-
Gandhi, P.N.1
Chen, S.G.2
Wilson-Delfosse, A.L.3
-
64
-
-
84861476741
-
Dopamine induced neurodegeneration in a PINK1 model of Parkinson's disease
-
Gandhi S., Vaarmann A., Yao Z., Duchen M.R., Wood N.W., Abramov A.Y. Dopamine induced neurodegeneration in a PINK1 model of Parkinson's disease. PloS One 2012, 7:e37564.
-
(2012)
PloS One
, vol.7
-
-
Gandhi, S.1
Vaarmann, A.2
Yao, Z.3
Duchen, M.R.4
Wood, N.W.5
Abramov, A.Y.6
-
65
-
-
77954885006
-
Alpha-Synuclein gene may interact with environmental factors in increasing risk of Parkinson's disease
-
Gatto N.M., Rhodes S.L., Manthripragada A.D., Bronstein J., Cockburn M., Farrer M., Ritz B. Alpha-Synuclein gene may interact with environmental factors in increasing risk of Parkinson's disease. Neuroepidemiology 2010, 35:191-195.
-
(2010)
Neuroepidemiology
, vol.35
, pp. 191-195
-
-
Gatto, N.M.1
Rhodes, S.L.2
Manthripragada, A.D.3
Bronstein, J.4
Cockburn, M.5
Farrer, M.6
Ritz, B.7
-
66
-
-
79956088518
-
Characterization of reduced and oxidized dopamine and 3,4-dihydrophenylacetic acid, on brain mitochondrial electron transport chain activities
-
Gautam A.H., Zeevalk G.D. Characterization of reduced and oxidized dopamine and 3,4-dihydrophenylacetic acid, on brain mitochondrial electron transport chain activities. Biochimica et Biophysica Acta 2011, 1807:819-828.
-
(2011)
Biochimica et Biophysica Acta
, vol.1807
, pp. 819-828
-
-
Gautam, A.H.1
Zeevalk, G.D.2
-
68
-
-
84863624459
-
Loss of DJ-1 does not affect mitochondrial respiration but increases ROS production and mitochondrial permeability transition pore opening
-
Giaime E., Yamaguchi H., Gautier C.A., Kitada T., Shen J. Loss of DJ-1 does not affect mitochondrial respiration but increases ROS production and mitochondrial permeability transition pore opening. PloS One 2012, 7:e40501.
-
(2012)
PloS One
, vol.7
-
-
Giaime, E.1
Yamaguchi, H.2
Gautier, C.A.3
Kitada, T.4
Shen, J.5
-
69
-
-
31144443248
-
The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity
-
Gloeckner C.J., Kinkl N., Schumacher A., Braun R.J., O'Neill E., Meitinger T., Kolch W., Prokisch H., Ueffing M. The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity. Human Molecular Genetics 2006, 15:223-232.
-
(2006)
Human Molecular Genetics
, vol.15
, pp. 223-232
-
-
Gloeckner, C.J.1
Kinkl, N.2
Schumacher, A.3
Braun, R.J.4
O'Neill, E.5
Meitinger, T.6
Kolch, W.7
Prokisch, H.8
Ueffing, M.9
-
70
-
-
13844253723
-
Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1
-
Goldberg M.S., Pisani A., Haburcak M., Vortherms T.A., Kitada T., Costa C., Tong Y., Martella G., Tscherter A., Martins A., Bernardi G., Roth B.L., Pothos E.N., Calabresi P., Shen J. Nigrostriatal dopaminergic deficits and hypokinesia caused by inactivation of the familial Parkinsonism-linked gene DJ-1. Neuron 2005, 45:489-496.
-
(2005)
Neuron
, vol.45
, pp. 489-496
-
-
Goldberg, M.S.1
Pisani, A.2
Haburcak, M.3
Vortherms, T.A.4
Kitada, T.5
Costa, C.6
Tong, Y.7
Martella, G.8
Tscherter, A.9
Martins, A.10
Bernardi, G.11
Roth, B.L.12
Pothos, E.N.13
Calabresi, P.14
Shen, J.15
-
71
-
-
43149115834
-
6-Hydroxydopamine (6-OHDA) induces Drp1-dependent mitochondrial fragmentation in SH-SY5Y cells
-
Gomez-Lazaro M., Bonekamp N.A., Galindo M.F., Jordan J., Schrader M. 6-Hydroxydopamine (6-OHDA) induces Drp1-dependent mitochondrial fragmentation in SH-SY5Y cells. Free Radical Biology & Medicine 2008, 44:1960-1969.
-
(2008)
Free Radical Biology & Medicine
, vol.44
, pp. 1960-1969
-
-
Gomez-Lazaro, M.1
Bonekamp, N.A.2
Galindo, M.F.3
Jordan, J.4
Schrader, M.5
-
72
-
-
79954599799
-
Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's disease
-
Good C.H., Hoffman A.F., Hoffer B.J., Chefer V.I., Shippenberg T.S., Backman C.M., Larsson N.G., Olson L., Gellhaar S., Galter D., Lupica C.R. Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's disease. FASEB Journal:Official Publication of the Federation of American Societies for Experimental Biology 2011, 25:1333-1344.
-
(2011)
FASEB Journal:Official Publication of the Federation of American Societies for Experimental Biology
, vol.25
, pp. 1333-1344
-
-
Good, C.H.1
Hoffman, A.F.2
Hoffer, B.J.3
Chefer, V.I.4
Shippenberg, T.S.5
Backman, C.M.6
Larsson, N.G.7
Olson, L.8
Gellhaar, S.9
Galter, D.10
Lupica, C.R.11
-
73
-
-
0020514306
-
Intracellular and extracellular electrophysiology of nigral dopaminergic neurons - 2 Action potential generating mechanisms and morphological correlates
-
Grace A.A., Bunney B.S. Intracellular and extracellular electrophysiology of nigral dopaminergic neurons - 2 Action potential generating mechanisms and morphological correlates. Neuroscience 1983, 10:317-331.
-
(1983)
Neuroscience
, vol.10
, pp. 317-331
-
-
Grace, A.A.1
Bunney, B.S.2
-
74
-
-
0037386532
-
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
-
Greene J.C., Whitworth A.J., Kuo I., Andrews L.A., Feany M.B., Pallanck L.J. Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants. Proceedings of the National Academy of Sciences of the United States of America 2003, 100:4078-4083.
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, pp. 4078-4083
-
-
Greene, J.C.1
Whitworth, A.J.2
Kuo, I.3
Andrews, L.A.4
Feany, M.B.5
Pallanck, L.J.6
-
75
-
-
33746267531
-
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin
-
Greggio E., Jain S., Kingsbury A., Bandopadhyay R., Lewis P., Kaganovich A., van der Brug M.P., Beilina A., Blackinton J., Thomas K.J., Ahmad R., Miller D.W., Kesavapany S., Singleton A., Lees A., Harvey R.J., Harvey K., Cookson M.R. Kinase activity is required for the toxic effects of mutant LRRK2/dardarin. Neurobiology of Disease 2006, 23:329-341.
-
(2006)
Neurobiology of Disease
, vol.23
, pp. 329-341
-
-
Greggio, E.1
Jain, S.2
Kingsbury, A.3
Bandopadhyay, R.4
Lewis, P.5
Kaganovich, A.6
van der Brug, M.P.7
Beilina, A.8
Blackinton, J.9
Thomas, K.J.10
Ahmad, R.11
Miller, D.W.12
Kesavapany, S.13
Singleton, A.14
Lees, A.15
Harvey, R.J.16
Harvey, K.17
Cookson, M.R.18
-
76
-
-
78649866553
-
Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1
-
Guzman J.N., Sanchez-Padilla J., Wokosin D., Kondapalli J., Ilijic E., Schumacker P.T., Surmeier D.J. Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1. Nature 2010, 468:696-700.
-
(2010)
Nature
, vol.468
, pp. 696-700
-
-
Guzman, J.N.1
Sanchez-Padilla, J.2
Wokosin, D.3
Kondapalli, J.4
Ilijic, E.5
Schumacker, P.T.6
Surmeier, D.J.7
-
77
-
-
0029050583
-
Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson's disease
-
Haas R.H., Nasirian F., Nakano K., Ward D., Pay M., Hill R., Shults C.W. Low platelet mitochondrial complex I and complex II/III activity in early untreated Parkinson's disease. Annals of Neurology 1995, 37:714-722.
-
(1995)
Annals of Neurology
, vol.37
, pp. 714-722
-
-
Haas, R.H.1
Nasirian, F.2
Nakano, K.3
Ward, D.4
Pay, M.5
Hill, R.6
Shults, C.W.7
-
78
-
-
18144406539
-
Oxidative stress and inflammation in Parkinson's disease: is there a causal link?
-
Hald A., Lotharius J. Oxidative stress and inflammation in Parkinson's disease: is there a causal link?. Experimental Neurology 2005, 193:279-290.
-
(2005)
Experimental Neurology
, vol.193
, pp. 279-290
-
-
Hald, A.1
Lotharius, J.2
-
79
-
-
33745280651
-
Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity
-
Hampe C., Ardila-Osorio H., Fournier M., Brice A., Corti O. Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity. Human Molecular Genetics 2006, 15:2059-2075.
-
(2006)
Human Molecular Genetics
, vol.15
, pp. 2059-2075
-
-
Hampe, C.1
Ardila-Osorio, H.2
Fournier, M.3
Brice, A.4
Corti, O.5
-
80
-
-
0027535984
-
Stable parkinsonian syndrome and uneven loss of striatal dopamine fibres following chronic MPTP administration in baboons
-
Hantraye P., Varastet M., Peschanski M., Riche D., Cesaro P., Willer J.C., Maziere M. Stable parkinsonian syndrome and uneven loss of striatal dopamine fibres following chronic MPTP administration in baboons. Neuroscience 1993, 53:169-178.
-
(1993)
Neuroscience
, vol.53
, pp. 169-178
-
-
Hantraye, P.1
Varastet, M.2
Peschanski, M.3
Riche, D.4
Cesaro, P.5
Willer, J.C.6
Maziere, M.7
-
81
-
-
0029844003
-
Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons
-
Hantraye P., Brouillet E., Ferrante R., Palfi S., Dolan R., Matthews R.T., Beal M.F. Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons. Nature Medicine 1996, 2:1017-1021.
-
(1996)
Nature Medicine
, vol.2
, pp. 1017-1021
-
-
Hantraye, P.1
Brouillet, E.2
Ferrante, R.3
Palfi, S.4
Dolan, R.5
Matthews, R.T.6
Beal, M.F.7
-
82
-
-
39449098267
-
Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP
-
Haque M.E., Thomas K.J., D'Souza C., Callaghan S., Kitada T., Slack R.S., Fraser P., Cookson M.R., Tandon A., Park D.S. Cytoplasmic Pink1 activity protects neurons from dopaminergic neurotoxin MPTP. Proceedings of the National Academy of Sciences of the United States of America 2008, 105:1716-1721.
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, pp. 1716-1721
-
-
Haque, M.E.1
Thomas, K.J.2
D'Souza, C.3
Callaghan, S.4
Kitada, T.5
Slack, R.S.6
Fraser, P.7
Cookson, M.R.8
Tandon, A.9
Park, D.S.10
-
83
-
-
12944250987
-
Caspase-3: a vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease
-
Hartmann A., Hunot S., Michel P.P., Muriel M.P., Vyas S., Faucheux B.A., Mouatt-Prigent A., Turmel H., Srinivasan A., Ruberg M., Evan G.I., Agid Y., Hirsch E.C. Caspase-3: a vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America 2000, 97:2875-2880.
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, pp. 2875-2880
-
-
Hartmann, A.1
Hunot, S.2
Michel, P.P.3
Muriel, M.P.4
Vyas, S.5
Faucheux, B.A.6
Mouatt-Prigent, A.7
Turmel, H.8
Srinivasan, A.9
Ruberg, M.10
Evan, G.I.11
Agid, Y.12
Hirsch, E.C.13
-
84
-
-
0035103294
-
Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease?
-
Hartmann A., Michel P.P., Troadec J.D., Mouatt-Prigent A., Faucheux B.A., Ruberg M., Agid Y., Hirsch E.C. Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease?. Journal of Neurochemistry 2001, 76:1785-1793.
-
(2001)
Journal of Neurochemistry
, vol.76
, pp. 1785-1793
-
-
Hartmann, A.1
Michel, P.P.2
Troadec, J.D.3
Mouatt-Prigent, A.4
Faucheux, B.A.5
Ruberg, M.6
Agid, Y.7
Hirsch, E.C.8
-
85
-
-
0035313071
-
Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis
-
Hartmann A., Troadec J.D., Hunot S., Kikly K., Faucheux B.A., Mouatt-Prigent A., Ruberg M., Agid Y., Hirsch E.C. Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis. The Journal of neuroscience:the official journal of the Society for Neuroscience 2001, 21:2247-2255.
-
(2001)
The Journal of neuroscience:the official journal of the Society for Neuroscience
, vol.21
, pp. 2247-2255
-
-
Hartmann, A.1
Troadec, J.D.2
Hunot, S.3
Kikly, K.4
Faucheux, B.A.5
Mouatt-Prigent, A.6
Ruberg, M.7
Agid, Y.8
Hirsch, E.C.9
-
86
-
-
0024997609
-
1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles
-
Hasegawa E., Takeshige K., Oishi T., Murai Y., Minakami S. 1-Methyl-4-phenylpyridinium (MPP+) induces NADH-dependent superoxide formation and enhances NADH-dependent lipid peroxidation in bovine heart submitochondrial particles. Biochemical and Biophysical Research Communications 1990, 170:1049-1055.
-
(1990)
Biochemical and Biophysical Research Communications
, vol.170
, pp. 1049-1055
-
-
Hasegawa, E.1
Takeshige, K.2
Oishi, T.3
Murai, Y.4
Minakami, S.5
-
87
-
-
0025942723
-
Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease
-
Hattori N., Tanaka M., Ozawa T., Mizuno Y. Immunohistochemical studies on complexes I, II, III, and IV of mitochondria in Parkinson's disease. Annals of Neurology 1991, 30:563-571.
-
(1991)
Annals of Neurology
, vol.30
, pp. 563-571
-
-
Hattori, N.1
Tanaka, M.2
Ozawa, T.3
Mizuno, Y.4
-
88
-
-
0021280826
-
Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice
-
Heikkila R.E., Hess A., Duvoisin R.C. Dopaminergic neurotoxicity of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine in mice. Science 1984, 224:1451-1453.
-
(1984)
Science
, vol.224
, pp. 1451-1453
-
-
Heikkila, R.E.1
Hess, A.2
Duvoisin, R.C.3
-
89
-
-
33847191686
-
Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling
-
Henn I.H., Bouman L., Schlehe J.S., Schlierf A., Schramm J.E., Wegener E., Nakaso K., Culmsee C., Berninger B., Krappmann D., Tatzelt J., Winklhofer K.F. Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling. The Journal of Neuroscience:the Official Journal of the Society for Neuroscience 2007, 27:1868-1878.
-
(2007)
The Journal of Neuroscience:the Official Journal of the Society for Neuroscience
, vol.27
, pp. 1868-1878
-
-
Henn, I.H.1
Bouman, L.2
Schlehe, J.S.3
Schlierf, A.4
Schramm, J.E.5
Wegener, E.6
Nakaso, K.7
Culmsee, C.8
Berninger, B.9
Krappmann, D.10
Tatzelt, J.11
Winklhofer, K.F.12
-
90
-
-
84863238102
-
DJ-1 null dopaminergic neuronal cells exhibit defects in mitochondrial function and structure: involvement of mitochondrial complex I assembly
-
Heo J.Y., Park J.H., Kim S.J., Seo K.S., Han J.S., Lee S.H., Kim J.M., Park J.I., Park S.K., Lim K., Hwang B.D., Shong M., Kweon G.R. DJ-1 null dopaminergic neuronal cells exhibit defects in mitochondrial function and structure: involvement of mitochondrial complex I assembly. PloS One 2012, 7:e32629.
-
(2012)
PloS One
, vol.7
-
-
Heo, J.Y.1
Park, J.H.2
Kim, S.J.3
Seo, K.S.4
Han, J.S.5
Lee, S.H.6
Kim, J.M.7
Park, J.I.8
Park, S.K.9
Lim, K.10
Hwang, B.D.11
Shong, M.12
Kweon, G.R.13
-
91
-
-
69249208792
-
Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease
-
Hoang T., Choi D.K., Nagai M., Wu D.C., Nagata T., Prou D., Wilson G.L., Vila M., Jackson-Lewis V., Dawson V.L., Dawson T.M., Chesselet M.F., Przedborski S. Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease. Free Radical Biology & Medicine 2009, 47:1049-1056.
-
(2009)
Free Radical Biology & Medicine
, vol.47
, pp. 1049-1056
-
-
Hoang, T.1
Choi, D.K.2
Nagai, M.3
Wu, D.C.4
Nagata, T.5
Prou, D.6
Wilson, G.L.7
Vila, M.8
Jackson-Lewis, V.9
Dawson, V.L.10
Dawson, T.M.11
Chesselet, M.F.12
Przedborski, S.13
-
92
-
-
33846288002
-
Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6
-
Hoepken H.H., Gispert S., Morales B., Wingerter O., Del Turco D., Mulsch A., Nussbaum R.L., Muller K., Drose S., Brandt U., Deller T., Wirth B., Kudin A.P., Kunz W.S., Auburger G. Mitochondrial dysfunction, peroxidation damage and changes in glutathione metabolism in PARK6. Neurobiology of Disease 2007, 25:401-411.
-
(2007)
Neurobiology of Disease
, vol.25
, pp. 401-411
-
-
Hoepken, H.H.1
Gispert, S.2
Morales, B.3
Wingerter, O.4
Del Turco, D.5
Mulsch, A.6
Nussbaum, R.L.7
Muller, K.8
Drose, S.9
Brandt, U.10
Deller, T.11
Wirth, B.12
Kudin, A.P.13
Kunz, W.S.14
Auburger, G.15
-
93
-
-
56349103980
-
The molecular mechanism of mitochondrial fusion
-
Hoppins S., Nunnari J. The molecular mechanism of mitochondrial fusion. Biochimica et Biophysica Acta 2009, 1793:20-26.
-
(2009)
Biochimica et Biophysica Acta
, vol.1793
, pp. 20-26
-
-
Hoppins, S.1
Nunnari, J.2
-
94
-
-
84863230106
-
Interaction between α-Synuclein and tau genotypes and the progression of parkinson's disease
-
Huang Y., Rowe D.B., Halliday G.M. Interaction between α-Synuclein and tau genotypes and the progression of parkinson's disease. Journal of Parkinson's Disease 2011, 1:271-276.
-
(2011)
Journal of Parkinson's Disease
, vol.1
, pp. 271-276
-
-
Huang, Y.1
Rowe, D.B.2
Halliday, G.M.3
-
95
-
-
84861749376
-
Alternative oxidase rescues mitochondria-mediated dopaminergic cell loss in Drosophila
-
Humphrey D.M., Parsons R.B., Ludlow Z.N., Riemensperger T., Esposito G., Verstreken P., Jacobs H.T., Birman S., Hirth F. Alternative oxidase rescues mitochondria-mediated dopaminergic cell loss in Drosophila. Human Molecular Genetics 2012, 21:2698-2712.
-
(2012)
Human Molecular Genetics
, vol.21
, pp. 2698-2712
-
-
Humphrey, D.M.1
Parsons, R.B.2
Ludlow, Z.N.3
Riemensperger, T.4
Esposito, G.5
Verstreken, P.6
Jacobs, H.T.7
Birman, S.8
Hirth, F.9
-
96
-
-
27844554819
-
Effect of overexpression of wild-type or mutant parkin on the cellular response induced by toxic insults
-
Hyun D.H., Lee M., Halliwell B., Jenner P. Effect of overexpression of wild-type or mutant parkin on the cellular response induced by toxic insults. Journal of Neuroscience Research 2005, 82:232-244.
-
(2005)
Journal of Neuroscience Research
, vol.82
, pp. 232-244
-
-
Hyun, D.H.1
Lee, M.2
Halliwell, B.3
Jenner, P.4
-
97
-
-
34447294546
-
Apoptotic mechanisms in mutant LRRK2-mediated cell death
-
Iaccarino C., Crosio C., Vitale C., Sanna G., Carri M.T., Barone P. Apoptotic mechanisms in mutant LRRK2-mediated cell death. Human Molecular Genetics 2007, 16:1319-1326.
-
(2007)
Human Molecular Genetics
, vol.16
, pp. 1319-1326
-
-
Iaccarino, C.1
Crosio, C.2
Vitale, C.3
Sanna, G.4
Carri, M.T.5
Barone, P.6
-
98
-
-
77956522541
-
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
-
Irrcher I., Aleyasin H., Seifert E.L., Hewitt S.J., Chhabra S., Phillips M., Lutz A.K., Rousseaux M.W., Bevilacqua L., Jahani-Asl A., Callaghan S., MacLaurin J.G., Winklhofer K.F., Rizzu P., Rippstein P., Kim R.H., Chen C.X., Fon E.A., Slack R.S., Harper M.E., McBride H.M., Mak T.W., Park D.S. Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics. Human Molecular Genetics 2010, 19:3734-3746.
-
(2010)
Human Molecular Genetics
, vol.19
, pp. 3734-3746
-
-
Irrcher, I.1
Aleyasin, H.2
Seifert, E.L.3
Hewitt, S.J.4
Chhabra, S.5
Phillips, M.6
Lutz, A.K.7
Rousseaux, M.W.8
Bevilacqua, L.9
Jahani-Asl, A.10
Callaghan, S.11
MacLaurin, J.G.12
Winklhofer, K.F.13
Rizzu, P.14
Rippstein, P.15
Kim, R.H.16
Chen, C.X.17
Fon, E.A.18
Slack, R.S.19
Harper, M.E.20
McBride, H.M.21
Mak, T.W.22
Park, D.S.23
more..
-
99
-
-
68249087424
-
Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice
-
Ishihara N., Nomura M., Jofuku A., Kato H., Suzuki S.O., Masuda K., Otera H., Nakanishi Y., Nonaka I., Goto Y., Taguchi N., Morinaga H., Maeda M., Takayanagi R., Yokota S., Mihara K. Mitochondrial fission factor Drp1 is essential for embryonic development and synapse formation in mice. Nature Cell Biology 2009, 11:958-966.
-
(2009)
Nature Cell Biology
, vol.11
, pp. 958-966
-
-
Ishihara, N.1
Nomura, M.2
Jofuku, A.3
Kato, H.4
Suzuki, S.O.5
Masuda, K.6
Otera, H.7
Nakanishi, Y.8
Nonaka, I.9
Goto, Y.10
Taguchi, N.11
Morinaga, H.12
Maeda, M.13
Takayanagi, R.14
Yokota, S.15
Mihara, K.16
-
100
-
-
72649092390
-
Levels of reduced and oxidized coenzyme Q-10 and 8-hydroxy-2'-deoxyguanosine in the cerebrospinal fluid of patients with living Parkinson's disease demonstrate that mitochondrial oxidative damage and/or oxidative DNA damage contributes to the neurodegenerative process
-
Isobe C., Abe T., Terayama Y. Levels of reduced and oxidized coenzyme Q-10 and 8-hydroxy-2'-deoxyguanosine in the cerebrospinal fluid of patients with living Parkinson's disease demonstrate that mitochondrial oxidative damage and/or oxidative DNA damage contributes to the neurodegenerative process. Neuroscience Letters 2010, 469:159-163.
-
(2010)
Neuroscience Letters
, vol.469
, pp. 159-163
-
-
Isobe, C.1
Abe, T.2
Terayama, Y.3
-
101
-
-
0034001572
-
Mechanisms of toxicity, clinical features, and management of diquat poisoning: a review
-
Jones G.M., Vale J.A. Mechanisms of toxicity, clinical features, and management of diquat poisoning: a review. Journal of Toxicology Clinical Toxicology 2000, 38:123-128.
-
(2000)
Journal of Toxicology Clinical Toxicology
, vol.38
, pp. 123-128
-
-
Jones, G.M.1
Vale, J.A.2
-
102
-
-
63049138430
-
Mitochondrial localization of DJ-1 leads to enhanced neuroprotection
-
Junn E., Jang W.H., Zhao X., Jeong B.S., Mouradian M.M. Mitochondrial localization of DJ-1 leads to enhanced neuroprotection. Journal of Neuroscience Research 2009, 87:123-129.
-
(2009)
Journal of Neuroscience Research
, vol.87
, pp. 123-129
-
-
Junn, E.1
Jang, W.H.2
Zhao, X.3
Jeong, B.S.4
Mouradian, M.M.5
-
103
-
-
77952545692
-
Caffeine protects against combined paraquat and maneb-induced dopaminergic neuron degeneration
-
Kachroo A., Irizarry M.C., Schwarzschild M.A. Caffeine protects against combined paraquat and maneb-induced dopaminergic neuron degeneration. Experimental Neurology 2010, 223:657-661.
-
(2010)
Experimental Neurology
, vol.223
, pp. 657-661
-
-
Kachroo, A.1
Irizarry, M.C.2
Schwarzschild, M.A.3
-
104
-
-
33646948530
-
Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled
-
Keeney P.M., Xie J., Capaldi R.A., Bennett J.P. Parkinson's disease brain mitochondrial complex I has oxidatively damaged subunits and is functionally impaired and misassembled. The Journal of Neuroscience:the Official Journal of the Society for Neuroscience 2006, 26:5256-5264.
-
(2006)
The Journal of Neuroscience:the Official Journal of the Society for Neuroscience
, vol.26
, pp. 5256-5264
-
-
Keeney, P.M.1
Xie, J.2
Capaldi, R.A.3
Bennett, J.P.4
-
105
-
-
20144389422
-
Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress
-
Kim R.H., Smith P.D., Aleyasin H., Hayley S., Mount M.P., Pownall S., Wakeham A., You-Ten A.J., Kalia S.K., Horne P., Westaway D., Lozano A.M., Anisman H., Park D.S., Mak T.W. Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress. Proceedings of the National Academy of Sciences of the United States of America 2005, 102:5215-5220.
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, pp. 5215-5220
-
-
Kim, R.H.1
Smith, P.D.2
Aleyasin, H.3
Hayley, S.4
Mount, M.P.5
Pownall, S.6
Wakeham, A.7
You-Ten, A.J.8
Kalia, S.K.9
Horne, P.10
Westaway, D.11
Lozano, A.M.12
Anisman, H.13
Park, D.S.14
Mak, T.W.15
-
106
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T., Asakawa S., Hattori N., Matsumine H., Yamamura Y., Minoshima S., Yokochi M., Mizuno Y., Shimizu N. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998, 392:605-608.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
Yokochi, M.7
Mizuno, Y.8
Shimizu, N.9
-
107
-
-
34547489872
-
Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice
-
Kitada T., Pisani A., Porter D.R., Yamaguchi H., Tscherter A., Martella G., Bonsi P., Zhang C., Pothos E.N., Shen J. Impaired dopamine release and synaptic plasticity in the striatum of PINK1-deficient mice. Proceedings of the National Academy of Sciences of the United States of America 2007, 104:11441-11446.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 11441-11446
-
-
Kitada, T.1
Pisani, A.2
Porter, D.R.3
Yamaguchi, H.4
Tscherter, A.5
Martella, G.6
Bonsi, P.7
Zhang, C.8
Pothos, E.N.9
Shen, J.10
-
108
-
-
33644610520
-
The genetics of Parkinson disease: implications for neurological care
-
Klein C., Schlossmacher M.G. The genetics of Parkinson disease: implications for neurological care. Nature Clinical Practice Neurology 2006, 2:136-146.
-
(2006)
Nature Clinical Practice Neurology
, vol.2
, pp. 136-146
-
-
Klein, C.1
Schlossmacher, M.G.2
-
109
-
-
33244460534
-
Mice lacking alpha-synuclein are resistant to mitochondrial toxins
-
Klivenyi P., Siwek D., Gardian G., Yang L., Starkov A., Cleren C., Ferrante R.J., Kowall N.W., Abeliovich A., Beal M.F. Mice lacking alpha-synuclein are resistant to mitochondrial toxins. Neurobiology of Disease 2006, 21:541-548.
-
(2006)
Neurobiology of Disease
, vol.21
, pp. 541-548
-
-
Klivenyi, P.1
Siwek, D.2
Gardian, G.3
Yang, L.4
Starkov, A.5
Cleren, C.6
Ferrante, R.J.7
Kowall, N.W.8
Abeliovich, A.9
Beal, M.F.10
-
110
-
-
57649210194
-
Impairing the mitochondrial fission and fusion balance: a new mechanism of neurodegeneration
-
Knott A.B., Bossy-Wetzel E. Impairing the mitochondrial fission and fusion balance: a new mechanism of neurodegeneration. Annals of the New York Academy of Sciences 2008, 1147:283-292.
-
(2008)
Annals of the New York Academy of Sciences
, vol.1147
, pp. 283-292
-
-
Knott, A.B.1
Bossy-Wetzel, E.2
-
111
-
-
33646351299
-
Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons
-
Kraytsberg Y., Kudryavtseva E., McKee A.C., Geula C., Kowall N.W., Khrapko K. Mitochondrial DNA deletions are abundant and cause functional impairment in aged human substantia nigra neurons. Nature Genetics 2006, 38:518-520.
-
(2006)
Nature Genetics
, vol.38
, pp. 518-520
-
-
Kraytsberg, Y.1
Kudryavtseva, E.2
McKee, A.C.3
Geula, C.4
Kowall, N.W.5
Khrapko, K.6
-
112
-
-
77949623516
-
Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1
-
Krebiehl G., Ruckerbauer S., Burbulla L.F., Kieper N., Maurer B., Waak J., Wolburg H., Gizatullina Z., Gellerich F.N., Woitalla D., Riess O., Kahle P.J., Proikas-Cezanne T., Kruger R. Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1. PloS One 2010, 5:e9367.
-
(2010)
PloS One
, vol.5
-
-
Krebiehl, G.1
Ruckerbauer, S.2
Burbulla, L.F.3
Kieper, N.4
Maurer, B.5
Waak, J.6
Wolburg, H.7
Gizatullina, Z.8
Gellerich, F.N.9
Woitalla, D.10
Riess, O.11
Kahle, P.J.12
Proikas-Cezanne, T.13
Kruger, R.14
-
113
-
-
0026484964
-
Platelet mitochondrial function in Parkinson's disease. The Royal Kings and Queens Parkinson Disease Research Group
-
Krige D., Carroll M.T., Cooper J.M., Marsden C.D., Schapira A.H. Platelet mitochondrial function in Parkinson's disease. The Royal Kings and Queens Parkinson Disease Research Group. Annals of Neurology 1992, 32:782-788.
-
(1992)
Annals of Neurology
, vol.32
, pp. 782-788
-
-
Krige, D.1
Carroll, M.T.2
Cooper, J.M.3
Marsden, C.D.4
Schapira, A.H.5
-
114
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Kruger R., Kuhn W., Muller T., Woitalla D., Graeber M., Kosel S., Przuntek H., Epplen J.T., Schols L., Riess O. Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nature Genetics 1998, 18:106-108.
-
(1998)
Nature Genetics
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
Woitalla, D.4
Graeber, M.5
Kosel, S.6
Przuntek, H.7
Epplen, J.T.8
Schols, L.9
Riess, O.10
-
115
-
-
41449089840
-
Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy
-
Kruse S.E., Watt W.C., Marcinek D.J., Kapur R.P., Schenkman K.A., Palmiter R.D. Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy. Cell Metabolism 2008, 7:312-320.
-
(2008)
Cell Metabolism
, vol.7
, pp. 312-320
-
-
Kruse, S.E.1
Watt, W.C.2
Marcinek, D.J.3
Kapur, R.P.4
Schenkman, K.A.5
Palmiter, R.D.6
-
116
-
-
33644778845
-
Parkin enhances mitochondrial biogenesis in proliferating cells
-
Kuroda Y., Mitsui T., Kunishige M., Shono M., Akaike M., Azuma H., Matsumoto T. Parkin enhances mitochondrial biogenesis in proliferating cells. Human Molecular Genetics 2006, 15:883-895.
-
(2006)
Human Molecular Genetics
, vol.15
, pp. 883-895
-
-
Kuroda, Y.1
Mitsui, T.2
Kunishige, M.3
Shono, M.4
Akaike, M.5
Azuma, H.6
Matsumoto, T.7
-
117
-
-
79952618692
-
DJ-1 mediates paraquat-induced dopaminergic neuronal cell death
-
Kwon H.J., Heo J.Y., Shim J.H., Park J.H., Seo K.S., Ryu M.J., Han J.S., Shong M., Son J.H., Kweon G.R. DJ-1 mediates paraquat-induced dopaminergic neuronal cell death. Toxicology Letters 2011, 202:85-92.
-
(2011)
Toxicology Letters
, vol.202
, pp. 85-92
-
-
Kwon, H.J.1
Heo, J.Y.2
Shim, J.H.3
Park, J.H.4
Seo, K.S.5
Ryu, M.J.6
Han, J.S.7
Shong, M.8
Son, J.H.9
Kweon, G.R.10
-
118
-
-
0020680904
-
Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis
-
Langston J.W., Ballard P., Tetrud J.W., Irwin I. Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. Science 1983, 219:979-980.
-
(1983)
Science
, vol.219
, pp. 979-980
-
-
Langston, J.W.1
Ballard, P.2
Tetrud, J.W.3
Irwin, I.4
-
119
-
-
0021263249
-
1-Methyl-4-phenylpyridinium ion (MPP+): identification of a metabolite of MPTP, a toxin selective to the substantia nigra
-
Langston J.W., Irwin I., Langston E.B., Forno L.S. 1-Methyl-4-phenylpyridinium ion (MPP+): identification of a metabolite of MPTP, a toxin selective to the substantia nigra. Neuroscience Letters 1984, 48:87-92.
-
(1984)
Neuroscience Letters
, vol.48
, pp. 87-92
-
-
Langston, J.W.1
Irwin, I.2
Langston, E.B.3
Forno, L.S.4
-
120
-
-
0032829070
-
Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure
-
Langston J.W., Forno L.S., Tetrud J., Reeves A.G., Kaplan J.A., Karluk D. Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure. Annals of Neurology 1999, 46:598-605.
-
(1999)
Annals of Neurology
, vol.46
, pp. 598-605
-
-
Langston, J.W.1
Forno, L.S.2
Tetrud, J.3
Reeves, A.G.4
Kaplan, J.A.5
Karluk, D.6
-
121
-
-
33750361540
-
A century-old debate on protein aggregation and neurodegeneration enters the clinic
-
Lansbury P.T., Lashuel H.A. A century-old debate on protein aggregation and neurodegeneration enters the clinic. Nature 2006, 443:774-779.
-
(2006)
Nature
, vol.443
, pp. 774-779
-
-
Lansbury, P.T.1
Lashuel, H.A.2
-
122
-
-
34748826792
-
Localization of alpha-synuclein to mitochondria within midbrain of mice
-
Li W.W., Yang R., Guo J.C., Ren H.M., Zha X.L., Cheng J.S., Cai D.F. Localization of alpha-synuclein to mitochondria within midbrain of mice. Neuroreport 2007, 18:1543-1546.
-
(2007)
Neuroreport
, vol.18
, pp. 1543-1546
-
-
Li, W.W.1
Yang, R.2
Guo, J.C.3
Ren, H.M.4
Zha, X.L.5
Cheng, J.S.6
Cai, D.F.7
-
123
-
-
33846460819
-
Mitochondria mass is low in mouse substantia nigra dopamine neurons: implications for Parkinson's disease
-
Liang C.L., Wang T.T., Luby-Phelps K., German D.C. Mitochondria mass is low in mouse substantia nigra dopamine neurons: implications for Parkinson's disease. Experimental Neurology 2007, 203:370-380.
-
(2007)
Experimental Neurology
, vol.203
, pp. 370-380
-
-
Liang, C.L.1
Wang, T.T.2
Luby-Phelps, K.3
German, D.C.4
-
124
-
-
20044386298
-
Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation
-
Lim K.L., Chew K.C., Tan J.M., Wang C., Chung K.K., Zhang Y., Tanaka Y., Smith W., Engelender S., Ross C.A., Dawson V.L., Dawson T.M. Parkin mediates nonclassical, proteasomal-independent ubiquitination of synphilin-1: implications for Lewy body formation. The Journal of Neuroscience:the Official Journal of the Society for Neuroscience 2005, 25:2002-2009.
-
(2005)
The Journal of Neuroscience:the Official Journal of the Society for Neuroscience
, vol.25
, pp. 2002-2009
-
-
Lim, K.L.1
Chew, K.C.2
Tan, J.M.3
Wang, C.4
Chung, K.K.5
Zhang, Y.6
Tanaka, Y.7
Smith, W.8
Engelender, S.9
Ross, C.A.10
Dawson, V.L.11
Dawson, T.M.12
-
125
-
-
4544273256
-
Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: clinical and molecular genetic study
-
Luoma P., Melberg A., Rinne J.O., Kaukonen J.A., Nupponen N.N., Chalmers R.M., Oldfors A., Rautakorpi I., Peltonen L., Majamaa K., Somer H., Suomalainen A. Parkinsonism, premature menopause, and mitochondrial DNA polymerase gamma mutations: clinical and molecular genetic study. Lancet 2004, 364:875-882.
-
(2004)
Lancet
, vol.364
, pp. 875-882
-
-
Luoma, P.1
Melberg, A.2
Rinne, J.O.3
Kaukonen, J.A.4
Nupponen, N.N.5
Chalmers, R.M.6
Oldfors, A.7
Rautakorpi, I.8
Peltonen, L.9
Majamaa, K.10
Somer, H.11
Suomalainen, A.12
-
126
-
-
76849117517
-
Genome-wide microarray analysis of the differential neuroprotective effects of antioxidants in neuroblastoma cells overexpressing the familial Parkinson's disease alpha-synuclein A53T mutation
-
Ma L., Cao T.T., Kandpal G., Warren L., Fred Hess J., Seabrook G.R., Ray W.J. Genome-wide microarray analysis of the differential neuroprotective effects of antioxidants in neuroblastoma cells overexpressing the familial Parkinson's disease alpha-synuclein A53T mutation. Neurochemical Research 2010, 35:130-142.
-
(2010)
Neurochemical Research
, vol.35
, pp. 130-142
-
-
Ma, L.1
Cao, T.T.2
Kandpal, G.3
Warren, L.4
Fred Hess, J.5
Seabrook, G.R.6
Ray, W.J.7
-
127
-
-
77956174949
-
Oxidative stress alters the regulatory control of p66Shc and Akt in PINK1 deficient cells
-
Maj M.C., Tkachyova I., Patel P., Addis J.B., Mackay N., Levandovskiy V., Lee J., Lang A.E., Cameron J.M., Robinson B.H. Oxidative stress alters the regulatory control of p66Shc and Akt in PINK1 deficient cells. Biochemical and Biophysical Research Communications 2010, 399:331-335.
-
(2010)
Biochemical and Biophysical Research Communications
, vol.399
, pp. 331-335
-
-
Maj, M.C.1
Tkachyova, I.2
Patel, P.3
Addis, J.B.4
Mackay, N.5
Levandovskiy, V.6
Lee, J.7
Lang, A.E.8
Cameron, J.M.9
Robinson, B.H.10
-
128
-
-
34548741834
-
RAAV-mediated nigral human parkin over-expression partially ameliorates motor deficits via enhanced dopamine neurotransmission in a rat model of Parkinson's disease
-
Manfredsson F.P., Burger C., Sullivan L.F., Muzyczka N., Lewin A.S., Mandel R.J. rAAV-mediated nigral human parkin over-expression partially ameliorates motor deficits via enhanced dopamine neurotransmission in a rat model of Parkinson's disease. Experimental Neurology 2007, 207:289-301.
-
(2007)
Experimental Neurology
, vol.207
, pp. 289-301
-
-
Manfredsson, F.P.1
Burger, C.2
Sullivan, L.F.3
Muzyczka, N.4
Lewin, A.S.5
Mandel, R.J.6
-
129
-
-
0021137683
-
Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism
-
Markey S.P., Johannessen J.N., Chiueh C.C., Burns R.S., Herkenham M.A. Intraneuronal generation of a pyridinium metabolite may cause drug-induced parkinsonism. Nature 1984, 311:464-467.
-
(1984)
Nature
, vol.311
, pp. 464-467
-
-
Markey, S.P.1
Johannessen, J.N.2
Chiueh, C.C.3
Burns, R.S.4
Herkenham, M.A.5
-
130
-
-
30644471051
-
Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death
-
Martin L.J., Pan Y., Price A.C., Sterling W., Copeland N.G., Jenkins N.A., Price D.L., Lee M.K. Parkinson's disease alpha-synuclein transgenic mice develop neuronal mitochondrial degeneration and cell death. The Journal of Neuroscience:the Official Journal of the Society for Neuroscience 2006, 26:41-50.
-
(2006)
The Journal of Neuroscience:the Official Journal of the Society for Neuroscience
, vol.26
, pp. 41-50
-
-
Martin, L.J.1
Pan, Y.2
Price, A.C.3
Sterling, W.4
Copeland, N.G.5
Jenkins, N.A.6
Price, D.L.7
Lee, M.K.8
-
131
-
-
33646151866
-
LRRK2 in Parkinson's disease: protein domains and functional insights
-
Mata I.F., Wedemeyer W.J., Farrer M.J., Taylor J.P., Gallo K.A. LRRK2 in Parkinson's disease: protein domains and functional insights. Trends in Neurosciences 2006, 29:286-293.
-
(2006)
Trends in Neurosciences
, vol.29
, pp. 286-293
-
-
Mata, I.F.1
Wedemeyer, W.J.2
Farrer, M.J.3
Taylor, J.P.4
Gallo, K.A.5
-
132
-
-
57049143140
-
Mitochondria in neuroplasticity and neurological disorders
-
Mattson M.P., Gleichmann M., Cheng A. Mitochondria in neuroplasticity and neurological disorders. Neuron 2008, 60:748-766.
-
(2008)
Neuron
, vol.60
, pp. 748-766
-
-
Mattson, M.P.1
Gleichmann, M.2
Cheng, A.3
-
133
-
-
0036075892
-
Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat
-
McCormack A.L., Thiruchelvam M., Manning-Bog A.B., Thiffault C., Langston J.W., Cory-Slechta D.A., Di Monte D.A. Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat. Neurobiology of Disease 2002, 10:119-127.
-
(2002)
Neurobiology of Disease
, vol.10
, pp. 119-127
-
-
McCormack, A.L.1
Thiruchelvam, M.2
Manning-Bog, A.B.3
Thiffault, C.4
Langston, J.W.5
Cory-Slechta, D.A.6
Di Monte, D.A.7
-
134
-
-
84859699540
-
Animal models of the non-motor features of Parkinson's disease
-
McDowell K., Chesselet M.F. Animal models of the non-motor features of Parkinson's disease. Neurobiology of Disease 2012, 46:597-606.
-
(2012)
Neurobiology of Disease
, vol.46
, pp. 597-606
-
-
McDowell, K.1
Chesselet, M.F.2
-
135
-
-
0028064283
-
Parkinsonism after chronic exposure to the fungicide maneb (manganese ethylene-bis-dithiocarbamate)
-
Meco G., Bonifati V., Vanacore N., Fabrizio E. Parkinsonism after chronic exposure to the fungicide maneb (manganese ethylene-bis-dithiocarbamate). Scandinavian Journal of Work, Environment & Health 1994, 20:301-305.
-
(1994)
Scandinavian Journal of Work, Environment & Health
, vol.20
, pp. 301-305
-
-
Meco, G.1
Bonifati, V.2
Vanacore, N.3
Fabrizio, E.4
-
136
-
-
33947356299
-
Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis
-
Meuer K., Suppanz I.E., Lingor P., Planchamp V., Goricke B., Fichtner L., Braus G.H., Dietz G.P., Jakobs S., Bahr M., Weishaupt J.H. Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis. Cell Death and Differentiation 2007, 14:651-661.
-
(2007)
Cell Death and Differentiation
, vol.14
, pp. 651-661
-
-
Meuer, K.1
Suppanz, I.E.2
Lingor, P.3
Planchamp, V.4
Goricke, B.5
Fichtner, L.6
Braus, G.H.7
Dietz, G.P.8
Jakobs, S.9
Bahr, M.10
Weishaupt, J.H.11
-
137
-
-
0024330311
-
Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease
-
Mizuno Y., Ohta S., Tanaka M., Takamiya S., Suzuki K., Sato T., Oya H., Ozawa T., Kagawa Y. Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease. Biochemical and Biophysical Research Communications 1989, 163:1450-1455.
-
(1989)
Biochemical and Biophysical Research Communications
, vol.163
, pp. 1450-1455
-
-
Mizuno, Y.1
Ohta, S.2
Tanaka, M.3
Takamiya, S.4
Suzuki, K.5
Sato, T.6
Oya, H.7
Ozawa, T.8
Kagawa, Y.9
-
138
-
-
0037413657
-
The role of oxidative stress in paraquat-induced neurotoxicity in rats: protection by non peptidyl superoxide dismutase mimetic
-
Mollace V., Iannone M., Muscoli C., Palma E., Granato T., Rispoli V., Nistico R., Rotiroti D., Salvemini D. The role of oxidative stress in paraquat-induced neurotoxicity in rats: protection by non peptidyl superoxide dismutase mimetic. Neuroscience Letters 2003, 335:163-166.
-
(2003)
Neuroscience Letters
, vol.335
, pp. 163-166
-
-
Mollace, V.1
Iannone, M.2
Muscoli, C.3
Palma, E.4
Granato, T.5
Rispoli, V.6
Nistico, R.7
Rotiroti, D.8
Salvemini, D.9
-
139
-
-
12344251678
-
Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress
-
Moore D.J., Zhang L., Troncoso J., Lee M.K., Hattori N., Mizuno Y., Dawson T.M., Dawson V.L. Association of DJ-1 and parkin mediated by pathogenic DJ-1 mutations and oxidative stress. Human Molecular Genetics 2005, 14:71-84.
-
(2005)
Human Molecular Genetics
, vol.14
, pp. 71-84
-
-
Moore, D.J.1
Zhang, L.2
Troncoso, J.3
Lee, M.K.4
Hattori, N.5
Mizuno, Y.6
Dawson, T.M.7
Dawson, V.L.8
-
140
-
-
0026587806
-
Differential vulnerability of primate caudate-putamen and striosome-matrix dopamine systems to the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
-
Moratalla R., Quinn B., DeLanney L.E., Irwin I., Langston J.W., Graybiel A.M. Differential vulnerability of primate caudate-putamen and striosome-matrix dopamine systems to the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proceedings of the National Academy of Sciences of the United States of America 1992, 89:3859-3863.
-
(1992)
Proceedings of the National Academy of Sciences of the United States of America
, vol.89
, pp. 3859-3863
-
-
Moratalla, R.1
Quinn, B.2
DeLanney, L.E.3
Irwin, I.4
Langston, J.W.5
Graybiel, A.M.6
-
142
-
-
78650025189
-
Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2
-
Mortiboys H., Johansen K.K., Aasly J.O., Bandmann O. Mitochondrial impairment in patients with Parkinson disease with the G2019S mutation in LRRK2. Neurology 2010, 75:2017-2020.
-
(2010)
Neurology
, vol.75
, pp. 2017-2020
-
-
Mortiboys, H.1
Johansen, K.K.2
Aasly, J.O.3
Bandmann, O.4
-
143
-
-
65249180086
-
Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons
-
Mosharov E.V., Larsen K.E., Kanter E., Phillips K.A., Wilson K., Schmitz Y., Krantz D.E., Kobayashi K., Edwards R.H., Sulzer D. Interplay between cytosolic dopamine, calcium, and alpha-synuclein causes selective death of substantia nigra neurons. Neuron 2009, 62:218-229.
-
(2009)
Neuron
, vol.62
, pp. 218-229
-
-
Mosharov, E.V.1
Larsen, K.E.2
Kanter, E.3
Phillips, K.A.4
Wilson, K.5
Schmitz, Y.6
Krantz, D.E.7
Kobayashi, K.8
Edwards, R.H.9
Sulzer, D.10
-
144
-
-
4544326057
-
Mitochondrial complex I and IV activities in leukocytes from patients with parkin mutations
-
Muftuoglu M., Elibol B., Dalmizrak O., Ercan A., Kulaksiz G., Ogus H., Dalkara T., Ozer N. Mitochondrial complex I and IV activities in leukocytes from patients with parkin mutations. Movement Disorders:Official Journal of the Movement Disorder Society 2004, 19:544-548.
-
(2004)
Movement Disorders:Official Journal of the Movement Disorder Society
, vol.19
, pp. 544-548
-
-
Muftuoglu, M.1
Elibol, B.2
Dalmizrak, O.3
Ercan, A.4
Kulaksiz, G.5
Ogus, H.6
Dalkara, T.7
Ozer, N.8
-
145
-
-
33846471122
-
Proteasome-independent functions of ubiquitin in endocytosis and signaling
-
Mukhopadhyay D., Riezman H. Proteasome-independent functions of ubiquitin in endocytosis and signaling. Science 2007, 315:201-205.
-
(2007)
Science
, vol.315
, pp. 201-205
-
-
Mukhopadhyay, D.1
Riezman, H.2
-
146
-
-
0037426566
-
Coenzyme Q10 supplementation provides mild symptomatic benefit in patients with Parkinson's disease
-
Muller T., Buttner T., Gholipour A.F., Kuhn W. Coenzyme Q10 supplementation provides mild symptomatic benefit in patients with Parkinson's disease. Neuroscience Letters 2003, 341:201-204.
-
(2003)
Neuroscience Letters
, vol.341
, pp. 201-204
-
-
Muller, T.1
Buttner, T.2
Gholipour, A.F.3
Kuhn, W.4
-
147
-
-
10744224035
-
Pael-R is accumulated in Lewy bodies of Parkinson's disease
-
Murakami T., Shoji M., Imai Y., Inoue H., Kawarabayashi T., Matsubara E., Harigaya Y., Sasaki A., Takahashi R., Abe K. Pael-R is accumulated in Lewy bodies of Parkinson's disease. Annals of Neurology 2004, 55:439-442.
-
(2004)
Annals of Neurology
, vol.55
, pp. 439-442
-
-
Murakami, T.1
Shoji, M.2
Imai, Y.3
Inoue, H.4
Kawarabayashi, T.5
Matsubara, E.6
Harigaya, Y.7
Sasaki, A.8
Takahashi, R.9
Abe, K.10
-
148
-
-
58249093939
-
How mitochondria produce reactive oxygen species
-
Murphy M.P. How mitochondria produce reactive oxygen species. The Biochemical Journal 2009, 417:1-13.
-
(2009)
The Biochemical Journal
, vol.417
, pp. 1-13
-
-
Murphy, M.P.1
-
149
-
-
0028556287
-
Impaired oxidative decarboxylation of pyruvate in fibroblasts from patients with Parkinson's disease
-
Mytilineou C., Werner P., Molinari S., Di Rocco A., Cohen G., Yahr M.D. Impaired oxidative decarboxylation of pyruvate in fibroblasts from patients with Parkinson's disease. Journal of Neural Transmission Parkinson's Disease and Dementia Section 1994, 8:223-228.
-
(1994)
Journal of Neural Transmission Parkinson's Disease and Dementia Section
, vol.8
, pp. 223-228
-
-
Mytilineou, C.1
Werner, P.2
Molinari, S.3
Di Rocco, A.4
Cohen, G.5
Yahr, M.D.6
-
150
-
-
58149379599
-
Optical reporters for the conformation of alpha-synuclein reveal a specific interaction with mitochondria
-
Nakamura K., Nemani V.M., Wallender E.K., Kaehlcke K., Ott M., Edwards R.H. Optical reporters for the conformation of alpha-synuclein reveal a specific interaction with mitochondria. The Journal of Neuroscience:the Official Journal of the Society for Neuroscience 2008, 28:12305-12317.
-
(2008)
The Journal of Neuroscience:the Official Journal of the Society for Neuroscience
, vol.28
, pp. 12305-12317
-
-
Nakamura, K.1
Nemani, V.M.2
Wallender, E.K.3
Kaehlcke, K.4
Ott, M.5
Edwards, R.H.6
-
151
-
-
58149314211
-
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
-
Narendra D., Tanaka A., Suen D.F., Youle R.J. Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. The Journal of Cell Biology 2008, 183:795-803.
-
(2008)
The Journal of Cell Biology
, vol.183
, pp. 795-803
-
-
Narendra, D.1
Tanaka, A.2
Suen, D.F.3
Youle, R.J.4
-
152
-
-
75749156257
-
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
-
Narendra D.P., Jin S.M., Tanaka A., Suen D.F., Gautier C.A., Shen J., Cookson M.R., Youle R.J. PINK1 is selectively stabilized on impaired mitochondria to activate Parkin. PLoS Biology 2010, 8:e1000298.
-
(2010)
PLoS Biology
, vol.8
-
-
Narendra, D.P.1
Jin, S.M.2
Tanaka, A.3
Suen, D.F.4
Gautier, C.A.5
Shen, J.6
Cookson, M.R.7
Youle, R.J.8
-
153
-
-
57649178442
-
Oxidative stress and energy crises in neuronal dysfunction
-
Nicholls D.G. Oxidative stress and energy crises in neuronal dysfunction. Annals of the New York Academy of Sciences 2008, 1147:53-60.
-
(2008)
Annals of the New York Academy of Sciences
, vol.1147
, pp. 53-60
-
-
Nicholls, D.G.1
-
154
-
-
0021810979
-
Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
-
Nicklas W.J., Vyas I., Heikkila R.E. Inhibition of NADH-linked oxidation in brain mitochondria by 1-methyl-4-phenyl-pyridine, a metabolite of the neurotoxin, 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine. Life Sciences 1985, 36:2503-2508.
-
(1985)
Life Sciences
, vol.36
, pp. 2503-2508
-
-
Nicklas, W.J.1
Vyas, I.2
Heikkila, R.E.3
-
155
-
-
84863728713
-
Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via dynamin-like protein
-
Niu J., Yu M., Wang C., Xu Z. Leucine-rich repeat kinase 2 disturbs mitochondrial dynamics via dynamin-like protein. Journal of Neurochemistry 2012, 122:650-658.
-
(2012)
Journal of Neurochemistry
, vol.122
, pp. 650-658
-
-
Niu, J.1
Yu, M.2
Wang, C.3
Xu, Z.4
-
156
-
-
33947513592
-
Pesticide exposure exacerbates alpha-synucleinopathy in an A53T transgenic mouse model
-
Norris E.H., Uryu K., Leight S., Giasson B.I., Trojanowski J.Q., Lee V.M. Pesticide exposure exacerbates alpha-synucleinopathy in an A53T transgenic mouse model. The American Journal of Pathology 2007, 170:658-666.
-
(2007)
The American Journal of Pathology
, vol.170
, pp. 658-666
-
-
Norris, E.H.1
Uryu, K.2
Leight, S.3
Giasson, B.I.4
Trojanowski, J.Q.5
Lee, V.M.6
-
157
-
-
26644457407
-
A slowly developing dysfunction of dopaminergic nigrostriatal neurons induced by long-term paraquat administration in rats: an animal model of preclinical stages of Parkinson's disease?
-
Ossowska K., Wardas J., Smialowska M., Kuter K., Lenda T., Wieronska J.M., Zieba B., Nowak P., Dabrowska J., Bortel A., Kwiecinski A., Wolfarth S. A slowly developing dysfunction of dopaminergic nigrostriatal neurons induced by long-term paraquat administration in rats: an animal model of preclinical stages of Parkinson's disease?. The European Journal of Neuroscience 2005, 22:1294-1304.
-
(2005)
The European Journal of Neuroscience
, vol.22
, pp. 1294-1304
-
-
Ossowska, K.1
Wardas, J.2
Smialowska, M.3
Kuter, K.4
Lenda, T.5
Wieronska, J.M.6
Zieba, B.7
Nowak, P.8
Dabrowska, J.9
Bortel, A.10
Kwiecinski, A.11
Wolfarth, S.12
-
158
-
-
0030710487
-
Oxidative damage and fragmentation of mitochondrial DNA in cellular apoptosis
-
Ozawa T. Oxidative damage and fragmentation of mitochondrial DNA in cellular apoptosis. Bioscience Reports 1997, 17:237-250.
-
(1997)
Bioscience Reports
, vol.17
, pp. 237-250
-
-
Ozawa, T.1
-
159
-
-
8844266996
-
Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease
-
Paisan-Ruiz C., Jain S., Evans E.W., Gilks W.P., Simon J., van der Brug M., Lopez de Munain A., Aparicio S., Gil A.M., Khan N., Johnson J., Martinez J.R., Nicholl D., Carrera I.M., Pena A.S., de Silva R., Lees A., Marti-Masso J.F., Perez-Tur J., Wood N.W., Singleton A.B. Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease. Neuron 2004, 44:595-600.
-
(2004)
Neuron
, vol.44
, pp. 595-600
-
-
Paisan-Ruiz, C.1
Jain, S.2
Evans, E.W.3
Gilks, W.P.4
Simon, J.5
van der Brug, M.6
Lopez de Munain, A.7
Aparicio, S.8
Gil, A.M.9
Khan, N.10
Johnson, J.11
Martinez, J.R.12
Nicholl, D.13
Carrera, I.M.14
Pena, A.S.15
de Silva, R.16
Lees, A.17
Marti-Masso, J.F.18
Perez-Tur, J.19
Wood, N.W.20
Singleton, A.B.21
more..
-
160
-
-
2442481789
-
Mitochondrial dysfunction and oxidative damage in parkin-deficient mice
-
Palacino J.J., Sagi D., Goldberg M.S., Krauss S., Motz C., Wacker M., Klose J., Shen J. Mitochondrial dysfunction and oxidative damage in parkin-deficient mice. The Journal of Biological Chemistry 2004, 279:18614-18622.
-
(2004)
The Journal of Biological Chemistry
, vol.279
, pp. 18614-18622
-
-
Palacino, J.J.1
Sagi, D.2
Goldberg, M.S.3
Krauss, S.4
Motz, C.5
Wacker, M.6
Klose, J.7
Shen, J.8
-
161
-
-
42449095464
-
Mitochondrial association of alpha-synuclein causes oxidative stress
-
Parihar M.S., Parihar A., Fujita M., Hashimoto M., Ghafourifar P. Mitochondrial association of alpha-synuclein causes oxidative stress. Cellular and Molecular Life Sciences:CMLS 2008, 65:1272-1284.
-
(2008)
Cellular and Molecular Life Sciences:CMLS
, vol.65
, pp. 1272-1284
-
-
Parihar, M.S.1
Parihar, A.2
Fujita, M.3
Hashimoto, M.4
Ghafourifar, P.5
-
162
-
-
33745602748
-
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
-
Park J., Lee S.B., Lee S., Kim Y., Song S., Kim S., Bae E., Kim J., Shong M., Kim J.M., Chung J. Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin. Nature 2006, 441:1157-1161.
-
(2006)
Nature
, vol.441
, pp. 1157-1161
-
-
Park, J.1
Lee, S.B.2
Lee, S.3
Kim, Y.4
Song, S.5
Kim, S.6
Bae, E.7
Kim, J.8
Shong, M.9
Kim, J.M.10
Chung, J.11
-
163
-
-
57749194390
-
The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process
-
Park J., Lee G., Chung J. The PINK1-Parkin pathway is involved in the regulation of mitochondrial remodeling process. Biochemical and Biophysical Research Communications 2009, 378:518-523.
-
(2009)
Biochemical and Biophysical Research Communications
, vol.378
, pp. 518-523
-
-
Park, J.1
Lee, G.2
Chung, J.3
-
164
-
-
41749104745
-
Complex I deficiency in Parkinson's disease frontal cortex
-
Parker W.D., Parks J.K., Swerdlow R.H. Complex I deficiency in Parkinson's disease frontal cortex. Brain Research 2008, 1189:215-218.
-
(2008)
Brain Research
, vol.1189
, pp. 215-218
-
-
Parker, W.D.1
Parks, J.K.2
Swerdlow, R.H.3
-
165
-
-
33947282153
-
DJ-1 and Parkin modulate dopamine-dependent behavior and inhibit MPTP-induced nigral dopamine neuron loss in mice
-
Paterna J.C., Leng A., Weber E., Feldon J., Bueler H. DJ-1 and Parkin modulate dopamine-dependent behavior and inhibit MPTP-induced nigral dopamine neuron loss in mice. Molecular Therapy:the Journal of the American Society of Gene Therapy 2007, 15:698-704.
-
(2007)
Molecular Therapy:the Journal of the American Society of Gene Therapy
, vol.15
, pp. 698-704
-
-
Paterna, J.C.1
Leng, A.2
Weber, E.3
Feldon, J.4
Bueler, H.5
-
166
-
-
0033521095
-
Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease
-
Pennathur S., Jackson-Lewis V., Przedborski S., Heinecke J.W. Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease. The Journal of Biological Chemistry 1999, 274:34621-34628.
-
(1999)
The Journal of Biological Chemistry
, vol.274
, pp. 34621-34628
-
-
Pennathur, S.1
Jackson-Lewis, V.2
Przedborski, S.3
Heinecke, J.W.4
-
168
-
-
30044442094
-
Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage
-
Perier C., Tieu K., Guegan C., Caspersen C., Jackson-Lewis V., Carelli V., Martinuzzi A., Hirano M., Przedborski S., Vila M. Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage. Proceedings of the National Academy of Sciences of the United States of America 2005, 102:19126-19131.
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, pp. 19126-19131
-
-
Perier, C.1
Tieu, K.2
Guegan, C.3
Caspersen, C.4
Jackson-Lewis, V.5
Carelli, V.6
Martinuzzi, A.7
Hirano, M.8
Przedborski, S.9
Vila, M.10
-
169
-
-
34249947154
-
Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease
-
Perier C., Bove J., Wu D.C., Dehay B., Choi D.K., Jackson-Lewis V., Rathke-Hartlieb S., Bouillet P., Strasser A., Schulz J.B., Przedborski S., Vila M. Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America 2007, 104:8161-8166.
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, pp. 8161-8166
-
-
Perier, C.1
Bove, J.2
Wu, D.C.3
Dehay, B.4
Choi, D.K.5
Jackson-Lewis, V.6
Rathke-Hartlieb, S.7
Bouillet, P.8
Strasser, A.9
Schulz, J.B.10
Przedborski, S.11
Vila, M.12
-
170
-
-
28844439032
-
Proteomic analysis of parkin knockout mice: alterations in energy metabolism protein handling and synaptic function
-
Periquet M., Corti O., Jacquier S., Brice A. Proteomic analysis of parkin knockout mice: alterations in energy metabolism protein handling and synaptic function. Journal of Neurochemistry 2005, 95:1259-1276.
-
(2005)
Journal of Neurochemistry
, vol.95
, pp. 1259-1276
-
-
Periquet, M.1
Corti, O.2
Jacquier, S.3
Brice, A.4
-
171
-
-
2542560342
-
Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress
-
Pesah Y., Pham T., Burgess H., Middlebrooks B., Verstreken P., Zhou Y., Harding M., Bellen H., Mardon G. Drosophila parkin mutants have decreased mass and cell size and increased sensitivity to oxygen radical stress. Development 2004, 131:2183-2194.
-
(2004)
Development
, vol.131
, pp. 2183-2194
-
-
Pesah, Y.1
Pham, T.2
Burgess, H.3
Middlebrooks, B.4
Verstreken, P.5
Zhou, Y.6
Harding, M.7
Bellen, H.8
Mardon, G.9
-
172
-
-
26644440926
-
Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations
-
Petit A., Kawarai T., Paitel E., Sanjo N., Maj M., Scheid M., Chen F., Gu Y., Hasegawa H., Salehi-Rad S., Wang L., Rogaeva E., Fraser P., Robinson B., St George-Hyslop P., Tandon A. Wild-type PINK1 prevents basal and induced neuronal apoptosis, a protective effect abrogated by Parkinson disease-related mutations. The Journal of Biological Chemistry 2005, 280:34025-34032.
-
(2005)
The Journal of Biological Chemistry
, vol.280
, pp. 34025-34032
-
-
Petit, A.1
Kawarai, T.2
Paitel, E.3
Sanjo, N.4
Maj, M.5
Scheid, M.6
Chen, F.7
Gu, Y.8
Hasegawa, H.9
Salehi-Rad, S.10
Wang, L.11
Rogaeva, E.12
Fraser, P.13
Robinson, B.14
St George-Hyslop, P.15
Tandon, A.16
-
173
-
-
84859422737
-
Overexpression of TFAM, NRF-1 and myr-AKT protects the MPP(+)-induced mitochondrial dysfunctions in neuronal cells
-
Piao Y., Kim H.G., Oh M.S., Pak Y.K. Overexpression of TFAM, NRF-1 and myr-AKT protects the MPP(+)-induced mitochondrial dysfunctions in neuronal cells. Biochimica et Biophysica Acta 2012, 1820:577-585.
-
(2012)
Biochimica et Biophysica Acta
, vol.1820
, pp. 577-585
-
-
Piao, Y.1
Kim, H.G.2
Oh, M.S.3
Pak, Y.K.4
-
174
-
-
56349137588
-
Mitochondrial respiratory dysfunction in familiar parkinsonism associated with PINK1 mutation
-
Piccoli C., Sardanelli A., Scrima R., Ripoli M., Quarato G., D'Aprile A., Bellomo F., Scacco S., De Michele G., Filla A., Iuso A., Boffoli D., Capitanio N., Papa S. Mitochondrial respiratory dysfunction in familiar parkinsonism associated with PINK1 mutation. Neurochemical Research 2008, 33:2565-2574.
-
(2008)
Neurochemical Research
, vol.33
, pp. 2565-2574
-
-
Piccoli, C.1
Sardanelli, A.2
Scrima, R.3
Ripoli, M.4
Quarato, G.5
D'Aprile, A.6
Bellomo, F.7
Scacco, S.8
De Michele, G.9
Filla, A.10
Iuso, A.11
Boffoli, D.12
Capitanio, N.13
Papa, S.14
-
175
-
-
0029965334
-
Apamin-sensitive Ca(2+)-activated K+ channels regulate pacemaker activity in nigral dopamine neurons
-
Ping H.X., Shepard P.D. Apamin-sensitive Ca(2+)-activated K+ channels regulate pacemaker activity in nigral dopamine neurons. Neuroreport 1996, 7:809-814.
-
(1996)
Neuroreport
, vol.7
, pp. 809-814
-
-
Ping, H.X.1
Shepard, P.D.2
-
176
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos M.H., Lavedan C., Leroy E., Ide S.E., Dehejia A., Dutra A., Pike B., Root H., Rubenstein J., Boyer R., Stenroos E.S., Chandrasekharappa S., Athanassiadou A., Papapetropoulos T., Johnson W.G., Lazzarini A.M., Duvoisin R.C., Di Iorio G., Golbe L.I., Nussbaum R.L. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 1997, 276:2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
Ide, S.E.4
Dehejia, A.5
Dutra, A.6
Pike, B.7
Root, H.8
Rubenstein, J.9
Boyer, R.10
Stenroos, E.S.11
Chandrasekharappa, S.12
Athanassiadou, A.13
Papapetropoulos, T.14
Johnson, W.G.15
Lazzarini, A.M.16
Duvoisin, R.C.17
Di Iorio, G.18
Golbe, L.I.19
Nussbaum, R.L.20
more..
-
177
-
-
39449088321
-
The PINK1/Parkin pathway regulates mitochondrial morphology
-
Poole A.C., Thomas R.E., Andrews L.A., McBride H.M., Whitworth A.J., Pallanck L.J. The PINK1/Parkin pathway regulates mitochondrial morphology. Proceedings of the National Academy of Sciences of the United States of America 2008, 105:1638-1643.
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, pp. 1638-1643
-
-
Poole, A.C.1
Thomas, R.E.2
Andrews, L.A.3
McBride, H.M.4
Whitworth, A.J.5
Pallanck, L.J.6
-
178
-
-
14744305520
-
Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice - a model of familial Parkinson's disease
-
Poon H.F., Frasier M., Shreve N., Calabrese V., Wolozin B., Butterfield D.A. Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice - a model of familial Parkinson's disease. Neurobiology of Disease 2005, 18:492-498.
-
(2005)
Neurobiology of Disease
, vol.18
, pp. 492-498
-
-
Poon, H.F.1
Frasier, M.2
Shreve, N.3
Calabrese, V.4
Wolozin, B.5
Butterfield, D.A.6
-
179
-
-
35448961718
-
Prolonged toxicokinetics and toxicodynamics of paraquat in mouse brain
-
Prasad K., Winnik B., Thiruchelvam M.J., Buckley B., Mirochnitchenko O., Richfield E.K. Prolonged toxicokinetics and toxicodynamics of paraquat in mouse brain. Environmental Health Perspectives 2007, 115:1448-1453.
-
(2007)
Environmental Health Perspectives
, vol.115
, pp. 1448-1453
-
-
Prasad, K.1
Winnik, B.2
Thiruchelvam, M.J.3
Buckley, B.4
Mirochnitchenko, O.5
Richfield, E.K.6
-
180
-
-
34547127902
-
PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1
-
Pridgeon J.W., Olzmann J.A., Chin L.S., Li L. PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1. PLoS Biology 2007, 5:e172.
-
(2007)
PLoS Biology
, vol.5
-
-
Pridgeon, J.W.1
Olzmann, J.A.2
Chin, L.S.3
Li, L.4
-
181
-
-
0026583465
-
Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity
-
Przedborski S., Kostic V., Jackson-Lewis V., Naini A.B., Simonetti S., Fahn S., Carlson E., Epstein C.J., Cadet J.L. Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. The Journal of neuroscience:the official journal of the Society for Neuroscience 1992, 12:1658-1667.
-
(1992)
The Journal of neuroscience:the official journal of the Society for Neuroscience
, vol.12
, pp. 1658-1667
-
-
Przedborski, S.1
Kostic, V.2
Jackson-Lewis, V.3
Naini, A.B.4
Simonetti, S.5
Fahn, S.6
Carlson, E.7
Epstein, C.J.8
Cadet, J.L.9
-
182
-
-
0029984860
-
Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity
-
Przedborski S., Jackson-Lewis V., Yokoyama R., Shibata T., Dawson V.L., Dawson T.M. Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America 1996, 93:4565-4571.
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, pp. 4565-4571
-
-
Przedborski, S.1
Jackson-Lewis, V.2
Yokoyama, R.3
Shibata, T.4
Dawson, V.L.5
Dawson, T.M.6
-
184
-
-
0022516015
-
Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism
-
Ramsay R.R., Salach J.I., Dadgar J., Singer T.P. Inhibition of mitochondrial NADH dehydrogenase by pyridine derivatives and its possible relation to experimental and idiopathic parkinsonism. Biochemical and Biophysical Research Communications 1986, 135:269-275.
-
(1986)
Biochemical and Biophysical Research Communications
, vol.135
, pp. 269-275
-
-
Ramsay, R.R.1
Salach, J.I.2
Dadgar, J.3
Singer, T.P.4
-
185
-
-
79957937433
-
Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases
-
Reddy P.H., Reddy T.P., Manczak M., Calkins M.J., Shirendeb U., Mao P. Dynamin-related protein 1 and mitochondrial fragmentation in neurodegenerative diseases. Brain Research Reviews 2011, 67:103-118.
-
(2011)
Brain Research Reviews
, vol.67
, pp. 103-118
-
-
Reddy, P.H.1
Reddy, T.P.2
Manczak, M.3
Calkins, M.J.4
Shirendeb, U.5
Mao, P.6
-
186
-
-
57649210205
-
Mitochondrial DNA mutations in disease, aging, and neurodegeneration
-
Reeve A.K., Krishnan K.J., Turnbull D. Mitochondrial DNA mutations in disease, aging, and neurodegeneration. Annals of the New York Academy of Sciences 2008, 1147:21-29.
-
(2008)
Annals of the New York Academy of Sciences
, vol.1147
, pp. 21-29
-
-
Reeve, A.K.1
Krishnan, K.J.2
Turnbull, D.3
-
187
-
-
27644459974
-
Paraquat neurotoxicity is distinct from that of MPTP and rotenone
-
Richardson J.R., Quan Y., Sherer T.B., Greenamyre J.T., Miller G.W. Paraquat neurotoxicity is distinct from that of MPTP and rotenone. Toxicological Sciences: an Official Journal of the Society of Toxicology 2005, 88:193-201.
-
(2005)
Toxicological Sciences: an Official Journal of the Society of Toxicology
, vol.88
, pp. 193-201
-
-
Richardson, J.R.1
Quan, Y.2
Sherer, T.B.3
Greenamyre, J.T.4
Miller, G.W.5
-
189
-
-
67449159281
-
Dopamine transporter genetic variants and pesticides in Parkinson's disease
-
Ritz B.R., Manthripragada A.D., Costello S., Lincoln S.J., Farrer M.J., Cockburn M., Bronstein J. Dopamine transporter genetic variants and pesticides in Parkinson's disease. Environmental Health Perspectives 2009, 117:964-969.
-
(2009)
Environmental Health Perspectives
, vol.117
, pp. 964-969
-
-
Ritz, B.R.1
Manthripragada, A.D.2
Costello, S.3
Lincoln, S.J.4
Farrer, M.J.5
Cockburn, M.6
Bronstein, J.7
-
190
-
-
84866164284
-
Alpha-Synuclein genetic variants predict faster motor symptom progression in idiopathic Parkinson disease
-
Ritz B., Rhodes S.L., Bordelon Y., Bronstein J. Alpha-Synuclein genetic variants predict faster motor symptom progression in idiopathic Parkinson disease. PloS One 2012, 7:e36199.
-
(2012)
PloS One
, vol.7
-
-
Ritz, B.1
Rhodes, S.L.2
Bordelon, Y.3
Bronstein, J.4
-
191
-
-
79957827273
-
Maneb and paraquat-mediated neurotoxicity: involvement of peroxiredoxin/thioredoxin system
-
Roede J.R., Hansen J.M., Go Y.M., Jones D.P. Maneb and paraquat-mediated neurotoxicity: involvement of peroxiredoxin/thioredoxin system. Toxicological Sciences: an Official Journal of the Society of Toxicology 2011, 121:368-375.
-
(2011)
Toxicological Sciences: an Official Journal of the Society of Toxicology
, vol.121
, pp. 368-375
-
-
Roede, J.R.1
Hansen, J.M.2
Go, Y.M.3
Jones, D.P.4
-
192
-
-
0025247726
-
Dopamine neurons of the monkey midbrain: contingencies of responses to active touch during self-initiated arm movements
-
Romo R., Schultz W. Dopamine neurons of the monkey midbrain: contingencies of responses to active touch during self-initiated arm movements. Journal of Neurophysiology 1990, 63:592-606.
-
(1990)
Journal of Neurophysiology
, vol.63
, pp. 592-606
-
-
Romo, R.1
Schultz, W.2
-
193
-
-
33744963796
-
Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells
-
Rosen K.M., Veereshwarayya V., Moussa C.E., Fu Q., Goldberg M.S., Schlossmacher M.G., Shen J., Querfurth H.W. Parkin protects against mitochondrial toxins and beta-amyloid accumulation in skeletal muscle cells. The Journal of Biological Chemistry 2006, 281:12809-12816.
-
(2006)
The Journal of Biological Chemistry
, vol.281
, pp. 12809-12816
-
-
Rosen, K.M.1
Veereshwarayya, V.2
Moussa, C.E.3
Fu, Q.4
Goldberg, M.S.5
Schlossmacher, M.G.6
Shen, J.7
Querfurth, H.W.8
-
194
-
-
77955594704
-
Extended lifespan of Drosophila parkin mutants through sequestration of redox-active metals and enhancement of anti-oxidative pathways
-
Saini N., Oelhafen S., Hua H., Georgiev O., Schaffner W., Bueler H. Extended lifespan of Drosophila parkin mutants through sequestration of redox-active metals and enhancement of anti-oxidative pathways. Neurobiology of Disease 2010, 40:82-92.
-
(2010)
Neurobiology of Disease
, vol.40
, pp. 82-92
-
-
Saini, N.1
Oelhafen, S.2
Hua, H.3
Georgiev, O.4
Schaffner, W.5
Bueler, H.6
-
195
-
-
33745908586
-
Temporal effects of paraquat/maneb on microglial activation and dopamine neuronal loss in older rats
-
Saint-Pierre M., Tremblay M.E., Sik A., Gross R.E., Cicchetti F. Temporal effects of paraquat/maneb on microglial activation and dopamine neuronal loss in older rats. Journal of Neurochemistry 2006, 98:760-772.
-
(2006)
Journal of Neurochemistry
, vol.98
, pp. 760-772
-
-
Saint-Pierre, M.1
Tremblay, M.E.2
Sik, A.3
Gross, R.E.4
Cicchetti, F.5
-
197
-
-
0024390719
-
Mitochondrial complex I deficiency in Parkinson's disease
-
Schapira A.H., Cooper J.M., Dexter D., Jenner P., Clark J.B., Marsden C.D. Mitochondrial complex I deficiency in Parkinson's disease. Lancet 1989, 1:1269.
-
(1989)
Lancet
, vol.1
, pp. 1269
-
-
Schapira, A.H.1
Cooper, J.M.2
Dexter, D.3
Jenner, P.4
Clark, J.B.5
Marsden, C.D.6
-
198
-
-
0025254401
-
Mitochondrial complex I deficiency in Parkinson's disease
-
Schapira A.H., Cooper J.M., Dexter D., Clark J.B., Jenner P., Marsden C.D. Mitochondrial complex I deficiency in Parkinson's disease. Journal of Neurochemistry 1990, 54:823-827.
-
(1990)
Journal of Neurochemistry
, vol.54
, pp. 823-827
-
-
Schapira, A.H.1
Cooper, J.M.2
Dexter, D.3
Clark, J.B.4
Jenner, P.5
Marsden, C.D.6
-
199
-
-
79959305691
-
Mitochondria: the next (neurode)generation
-
Schon E.A., Przedborski S. Mitochondria: the next (neurode)generation. Neuron 2011, 70:1033-1053.
-
(2011)
Neuron
, vol.70
, pp. 1033-1053
-
-
Schon, E.A.1
Przedborski, S.2
-
200
-
-
44649150145
-
Mitochondrial localization of alpha-synuclein protein in alpha-synuclein overexpressing cells
-
Shavali S., Brown-Borg H.M., Ebadi M., Porter J. Mitochondrial localization of alpha-synuclein protein in alpha-synuclein overexpressing cells. Neuroscience Letters 2008, 439:125-128.
-
(2008)
Neuroscience Letters
, vol.439
, pp. 125-128
-
-
Shavali, S.1
Brown-Borg, H.M.2
Ebadi, M.3
Porter, J.4
-
201
-
-
0344198025
-
Mechanism of toxicity in rotenone models of Parkinson's disease
-
Sherer T.B., Betarbet R., Testa C.M., Seo B.B., Richardson J.R., Kim J.H., Miller G.W., Yagi T., Matsuno-Yagi A., Greenamyre J.T. Mechanism of toxicity in rotenone models of Parkinson's disease. The Journal of Neuroscience: the Official Journal of the Society for Neuroscience 2003, 23:10756-10764.
-
(2003)
The Journal of Neuroscience: the Official Journal of the Society for Neuroscience
, vol.23
, pp. 10756-10764
-
-
Sherer, T.B.1
Betarbet, R.2
Testa, C.M.3
Seo, B.B.4
Richardson, J.R.5
Kim, J.H.6
Miller, G.W.7
Yagi, T.8
Matsuno-Yagi, A.9
Greenamyre, J.T.10
-
202
-
-
0037847451
-
Paraquat induces long-lasting dopamine overflow through the excitotoxic pathway in the striatum of freely moving rats
-
Shimizu K., Matsubara K., Ohtaki K., Fujimaru S., Saito O., Shiono H. Paraquat induces long-lasting dopamine overflow through the excitotoxic pathway in the striatum of freely moving rats. Brain Research 2003, 976:243-252.
-
(2003)
Brain Research
, vol.976
, pp. 243-252
-
-
Shimizu, K.1
Matsubara, K.2
Ohtaki, K.3
Fujimaru, S.4
Saito, O.5
Shiono, H.6
-
203
-
-
0033933048
-
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase
-
Shimura H., Hattori N., Kubo S., Mizuno Y., Asakawa S., Minoshima S., Shimizu N., Iwai K., Chiba T., Tanaka K., Suzuki T. Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nature Genetics 2000, 25:302-305.
-
(2000)
Nature Genetics
, vol.25
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.3
Mizuno, Y.4
Asakawa, S.5
Minoshima, S.6
Shimizu, N.7
Iwai, K.8
Chiba, T.9
Tanaka, K.10
Suzuki, T.11
-
204
-
-
0345451597
-
Absorption, tolerability, and effects on mitochondrial activity of oral coenzyme Q10 in parkinsonian patients
-
Shults C.W., Beal M.F., Fontaine D., Nakano K., Haas R.H. Absorption, tolerability, and effects on mitochondrial activity of oral coenzyme Q10 in parkinsonian patients. Neurology 1998, 50:793-795.
-
(1998)
Neurology
, vol.50
, pp. 793-795
-
-
Shults, C.W.1
Beal, M.F.2
Fontaine, D.3
Nakano, K.4
Haas, R.H.5
-
205
-
-
84881029374
-
Agrochemicals, alpha-Synuclein, and Parkinson's Disease
-
Silva B.A., Breydo L., Fink A.L., Uversky V.N. Agrochemicals, alpha-Synuclein, and Parkinson's Disease. Molecular Neurobiology 2013, 47(2):598-612.
-
(2013)
Molecular Neurobiology
, vol.47
, Issue.2
, pp. 598-612
-
-
Silva, B.A.1
Breydo, L.2
Fink, A.L.3
Uversky, V.N.4
-
206
-
-
27944444154
-
Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism
-
Silvestri L., Caputo V., Bellacchio E., Atorino L., Dallapiccola B., Valente E.M., Casari G. Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism. Human Molecular Genetics 2005, 14:3477-3492.
-
(2005)
Human Molecular Genetics
, vol.14
, pp. 3477-3492
-
-
Silvestri, L.1
Caputo, V.2
Bellacchio, E.3
Atorino, L.4
Dallapiccola, B.5
Valente, E.M.6
Casari, G.7
-
207
-
-
0242300619
-
Alpha-Synuclein locus triplication causes Parkinson's disease
-
Singleton A.B., Farrer M., Johnson J., Singleton A., Hague S., Kachergus J., Hulihan M., Peuralinna T., Dutra A., Nussbaum R., Lincoln S., Crawley A., Hanson M., Maraganore D., Adler C., Cookson M.R., Muenter M., Baptista M., Miller D., Blancato J., Hardy J., Gwinn-Hardy K. alpha-Synuclein locus triplication causes Parkinson's disease. Science 2003, 302:841.
-
(2003)
Science
, vol.302
, pp. 841
-
-
Singleton, A.B.1
Farrer, M.2
Johnson, J.3
Singleton, A.4
Hague, S.5
Kachergus, J.6
Hulihan, M.7
Peuralinna, T.8
Dutra, A.9
Nussbaum, R.10
Lincoln, S.11
Crawley, A.12
Hanson, M.13
Maraganore, D.14
Adler, C.15
Cookson, M.R.16
Muenter, M.17
Baptista, M.18
Miller, D.19
Blancato, J.20
Hardy, J.21
Gwinn-Hardy, K.22
more..
-
208
-
-
33748993710
-
Kinase activity of mutant LRRK2 mediates neuronal toxicity
-
Smith W.W., Pei Z., Jiang H., Dawson V.L., Dawson T.M., Ross C.A. Kinase activity of mutant LRRK2 mediates neuronal toxicity. Nature Neuroscience 2006, 9:1231-1233.
-
(2006)
Nature Neuroscience
, vol.9
, pp. 1231-1233
-
-
Smith, W.W.1
Pei, Z.2
Jiang, H.3
Dawson, V.L.4
Dawson, T.M.5
Ross, C.A.6
-
209
-
-
1542617769
-
Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP
-
Song D.D., Shults C.W., Sisk A., Rockenstein E., Masliah E Enhanced substantia nigra mitochondrial pathology in human alpha-synuclein transgenic mice after treatment with MPTP. Experimental Neurology 2004, 186:158-172.
-
(2004)
Experimental Neurology
, vol.186
, pp. 158-172
-
-
Song, D.D.1
Shults, C.W.2
Sisk, A.3
Rockenstein, E.4
Masliah, E.5
-
210
-
-
84864759870
-
Rotenone-induced parkinsonism elicits behavioral impairments and differential expression of parkin, heat shock proteins and caspases in the rat
-
Sonia Angeline M., Chaterjee P., Anand K., Ambasta R.K., Kumar P. Rotenone-induced parkinsonism elicits behavioral impairments and differential expression of parkin, heat shock proteins and caspases in the rat. Neuroscience 2012, 220:291-301.
-
(2012)
Neuroscience
, vol.220
, pp. 291-301
-
-
Sonia Angeline, M.1
Chaterjee, P.2
Anand, K.3
Ambasta, R.K.4
Kumar, P.5
-
211
-
-
56349133547
-
Positioning mitochondrial plasticity within cellular signaling cascades
-
Soubannier V., McBride H.M. Positioning mitochondrial plasticity within cellular signaling cascades. Biochimica et Biophysica Acta 2009, 1793:154-170.
-
(2009)
Biochimica et Biophysica Acta
, vol.1793
, pp. 154-170
-
-
Soubannier, V.1
McBride, H.M.2
-
212
-
-
0034531475
-
The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy
-
Spillantini M.G., Goedert M. The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. Annals of the New York Academy of Sciences 2000, 920:16-27.
-
(2000)
Annals of the New York Academy of Sciences
, vol.920
, pp. 16-27
-
-
Spillantini, M.G.1
Goedert, M.2
-
213
-
-
0030882856
-
Alpha-synuclein in Lewy bodies
-
Spillantini M.G., Schmidt M.L., Lee V.M., Trojanowski J.Q., Jakes R., Goedert M. Alpha-synuclein in Lewy bodies. Nature 1997, 388:839-840.
-
(1997)
Nature
, vol.388
, pp. 839-840
-
-
Spillantini, M.G.1
Schmidt, M.L.2
Lee, V.M.3
Trojanowski, J.Q.4
Jakes, R.5
Goedert, M.6
-
214
-
-
57649233079
-
The role of mitochondria in reactive oxygen species metabolism and signaling
-
Starkov A.A. The role of mitochondria in reactive oxygen species metabolism and signaling. Annals of the New York Academy of Sciences 2008, 1147:37-52.
-
(2008)
Annals of the New York Academy of Sciences
, vol.1147
, pp. 37-52
-
-
Starkov, A.A.1
-
215
-
-
84856976662
-
Altered dopamine metabolism and increased vulnerability to MPTP in mice with partial deficiency of mitochondrial complex I in dopamine neurons
-
Sterky F.H., Hoffman A.F., Milenkovic D., Bao B., Paganelli A., Edgar D., Wibom R., Lupica C.R., Olson L., Larsson N.G. Altered dopamine metabolism and increased vulnerability to MPTP in mice with partial deficiency of mitochondrial complex I in dopamine neurons. Human Molecular Genetics 2012, 21:1078-1089.
-
(2012)
Human Molecular Genetics
, vol.21
, pp. 1078-1089
-
-
Sterky, F.H.1
Hoffman, A.F.2
Milenkovic, D.3
Bao, B.4
Paganelli, A.5
Edgar, D.6
Wibom, R.7
Lupica, C.R.8
Olson, L.9
Larsson, N.G.10
-
216
-
-
34447252358
-
Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease
-
Storch A., Jost W.H., Vieregge P., Spiegel J., Greulich W., Durner J., Muller T., Kupsch A., Henningsen H., Oertel W.H., Fuchs G., Kuhn W., Niklowitz P., Koch R., Herting B., Reichmann H. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q(10) in Parkinson disease. Archives of Neurology 2007, 64:938-944.
-
(2007)
Archives of Neurology
, vol.64
, pp. 938-944
-
-
Storch, A.1
Jost, W.H.2
Vieregge, P.3
Spiegel, J.4
Greulich, W.5
Durner, J.6
Muller, T.7
Kupsch, A.8
Henningsen, H.9
Oertel, W.H.10
Fuchs, G.11
Kuhn, W.12
Niklowitz, P.13
Koch, R.14
Herting, B.15
Reichmann, H.16
-
217
-
-
84870013071
-
Voltage-dependent anion channels (VDACs) recruit Parkin to defective mitochondria to promote mitochondrial autophagy
-
Sun Y., Vashisht A.A., Tchieu J., Wohlschlegel J.A., Dreier L. Voltage-dependent anion channels (VDACs) recruit Parkin to defective mitochondria to promote mitochondrial autophagy. The Journal of Biological Chemistry 2012, 287:40652-40660.
-
(2012)
The Journal of Biological Chemistry
, vol.287
, pp. 40652-40660
-
-
Sun, Y.1
Vashisht, A.A.2
Tchieu, J.3
Wohlschlegel, J.A.4
Dreier, L.5
-
218
-
-
34548657565
-
Calcium, ageing, and neuronal vulnerability in Parkinson's disease
-
Surmeier D.J. Calcium, ageing, and neuronal vulnerability in Parkinson's disease. Lancet Neurology 2007, 6:933-938.
-
(2007)
Lancet Neurology
, vol.6
, pp. 933-938
-
-
Surmeier, D.J.1
-
219
-
-
81255149611
-
The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease
-
Surmeier D.J., Guzman J.N., Sanchez-Padilla J., Schumacker PT The role of calcium and mitochondrial oxidant stress in the loss of substantia nigra pars compacta dopaminergic neurons in Parkinson's disease. Neuroscience 2011, 198:221-231.
-
(2011)
Neuroscience
, vol.198
, pp. 221-231
-
-
Surmeier, D.J.1
Guzman, J.N.2
Sanchez-Padilla, J.3
Schumacker, P.T.4
-
220
-
-
0034965086
-
Biochemical analysis of cybrids expressing mitochondrial DNA from Contursi kindred Parkinson's subjects
-
Swerdlow R.H., Parks J.K., Cassarino D.S., Binder D.R., Bennett J.P., Di Iorio G., Golbe L.I., Parker W.D. Biochemical analysis of cybrids expressing mitochondrial DNA from Contursi kindred Parkinson's subjects. Experimental Neurology 2001, 169:479-485.
-
(2001)
Experimental Neurology
, vol.169
, pp. 479-485
-
-
Swerdlow, R.H.1
Parks, J.K.2
Cassarino, D.S.3
Binder, D.R.4
Bennett, J.P.5
Di Iorio, G.6
Golbe, L.I.7
Parker, W.D.8
-
221
-
-
1642527499
-
DJ-1 has a role in antioxidative stress to prevent cell death
-
Taira T., Saito Y., Niki T., Iguchi-Ariga S.M., Takahashi K., Ariga H. DJ-1 has a role in antioxidative stress to prevent cell death. EMBO Reports 2004, 5:213-218.
-
(2004)
EMBO Reports
, vol.5
, pp. 213-218
-
-
Taira, T.1
Saito, Y.2
Niki, T.3
Iguchi-Ariga, S.M.4
Takahashi, K.5
Ariga, H.6
-
222
-
-
0035870881
-
Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis
-
Tanaka Y., Engelender S., Igarashi S., Rao R.K., Wanner T., Tanzi R.E., Sawa A.V., Dawson L.D., Ross CA T.M. Inducible expression of mutant alpha-synuclein decreases proteasome activity and increases sensitivity to mitochondria-dependent apoptosis. Human Molecular Genetics 2001, 10:919-926.
-
(2001)
Human Molecular Genetics
, vol.10
, pp. 919-926
-
-
Tanaka, Y.1
Engelender, S.2
Igarashi, S.3
Rao, R.K.4
Wanner, T.5
Tanzi, R.E.6
Sawa, A.V.7
Dawson, L.D.8
Ross, C.A.T.M.9
-
223
-
-
33744760852
-
Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease
-
Tang B., Xiong H., Sun P., Zhang Y., Wang D., Hu Z., Zhu Z., Ma H., Pan Q., Xia J.H., Xia K., Zhang Z Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease. Human Molecular Genetics 2006, 15:1816-1825.
-
(2006)
Human Molecular Genetics
, vol.15
, pp. 1816-1825
-
-
Tang, B.1
Xiong, H.2
Sun, P.3
Zhang, Y.4
Wang, D.5
Hu, Z.6
Zhu, Z.7
Ma, H.8
Pan, Q.9
Xia, J.H.10
Xia, K.11
Zhang, Z.12
-
224
-
-
79955557808
-
Rotenone, paraquat, and Parkinson's disease
-
Tanner C.M., Kamel F., Ross G.W., Hoppin J.A., Goldman S.M., Korell M., Marras C., Bhudhikanok G.S., Kasten M., Chade A.R., Comyns K., Richards M.B., Meng C., Priestley B., Fernandez H.H., Cambi F., Umbach D.M., Blair A., Sandler D.P., Langston J.W. Rotenone, paraquat, and Parkinson's disease. Environmental Health Perspectives 2011, 119:866-872.
-
(2011)
Environmental Health Perspectives
, vol.119
, pp. 866-872
-
-
Tanner, C.M.1
Kamel, F.2
Ross, G.W.3
Hoppin, J.A.4
Goldman, S.M.5
Korell, M.6
Marras, C.7
Bhudhikanok, G.S.8
Kasten, M.9
Chade, A.R.10
Comyns, K.11
Richards, M.B.12
Meng, C.13
Priestley, B.14
Fernandez, H.H.15
Cambi, F.16
Umbach, D.M.17
Blair, A.18
Sandler, D.P.19
Langston, J.W.20
more..
-
225
-
-
0036778511
-
Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype
-
Thiruchelvam M., Richfield E.K., Goodman B.M., Baggs R.B., Cory-Slechta D.A. Developmental exposure to the pesticides paraquat and maneb and the Parkinson's disease phenotype. Neurotoxicology 2002, 23:621-633.
-
(2002)
Neurotoxicology
, vol.23
, pp. 621-633
-
-
Thiruchelvam, M.1
Richfield, E.K.2
Goodman, B.M.3
Baggs, R.B.4
Cory-Slechta, D.A.5
-
226
-
-
20444471551
-
Overexpression of superoxide dismutase or glutathione peroxidase protects against the paraquat + maneb-induced Parkinson disease phenotype
-
Thiruchelvam M., Prokopenko O., Cory-Slechta D.A., Buckley B., Mirochnitchenko O. Overexpression of superoxide dismutase or glutathione peroxidase protects against the paraquat + maneb-induced Parkinson disease phenotype. The Journal of Biological Chemistry 2005, 280:22530-22539.
-
(2005)
The Journal of Biological Chemistry
, vol.280
, pp. 22530-22539
-
-
Thiruchelvam, M.1
Prokopenko, O.2
Cory-Slechta, D.A.3
Buckley, B.4
Mirochnitchenko, O.5
-
228
-
-
38549110110
-
Fission and selective fusion govern mitochondrial segregation and elimination by autophagy
-
Twig G., Elorza A., Molina A.J., Mohamed H., Wikstrom J.D., Walzer G., Stiles L., Haigh S.E., Katz S., Las G., Alroy J., Wu M., Py B.F., Yuan J., Deeney J.T., Corkey B.E., Shirihai O.S. Fission and selective fusion govern mitochondrial segregation and elimination by autophagy. The EMBO Journal 2008, 27:433-446.
-
(2008)
The EMBO Journal
, vol.27
, pp. 433-446
-
-
Twig, G.1
Elorza, A.2
Molina, A.J.3
Mohamed, H.4
Wikstrom, J.D.5
Walzer, G.6
Stiles, L.7
Haigh, S.E.8
Katz, S.9
Las, G.10
Alroy, J.11
Wu, M.12
Py, B.F.13
Yuan, J.14
Deeney, J.T.15
Corkey, B.E.16
Shirihai, O.S.17
-
229
-
-
34548620297
-
Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation
-
Uversky V.N. Neuropathology, biochemistry, and biophysics of alpha-synuclein aggregation. Journal of Neurochemistry 2007, 103:17-37.
-
(2007)
Journal of Neurochemistry
, vol.103
, pp. 17-37
-
-
Uversky, V.N.1
-
230
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
Valente E.M., Abou-Sleiman P.M., Caputo V., Muqit M.M., Harvey K., Gispert S., Ali Z., Del Turco D., Bentivoglio A.R., Healy D.G., Albanese A., Nussbaum R., Gonzalez-Maldonado R., Deller T., Salvi S., Cortelli P., Gilks W.P., Latchman D.S., Harvey R.J., Dallapiccola B., Auburger G., Wood N.W. Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science 2004, 304:1158-1160.
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
Del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
Albanese, A.11
Nussbaum, R.12
Gonzalez-Maldonado, R.13
Deller, T.14
Salvi, S.15
Cortelli, P.16
Gilks, W.P.17
Latchman, D.S.18
Harvey, R.J.19
Dallapiccola, B.20
Auburger, G.21
Wood, N.W.22
more..
-
231
-
-
2942556985
-
Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress
-
Van Remmen H., Qi W., Sabia M., Freeman G., Estlack L., Yang H., Mao Guo Z., Huang T.T., Strong R., Lee S., Epstein C.J., Richardson A. Multiple deficiencies in antioxidant enzymes in mice result in a compound increase in sensitivity to oxidative stress. Free Radical Biology & Medicine 2004, 36:1625-1634.
-
(2004)
Free Radical Biology & Medicine
, vol.36
, pp. 1625-1634
-
-
Van Remmen, H.1
Qi, W.2
Sabia, M.3
Freeman, G.4
Estlack, L.5
Yang, H.6
Mao Guo, Z.7
Huang, T.T.8
Strong, R.9
Lee, S.10
Epstein, C.J.11
Richardson, A.12
-
232
-
-
0028171396
-
Chronic MPTP treatment reproduces in baboons the differential vulnerability of mesencephalic dopaminergic neurons observed in Parkinson's disease
-
Varastet M., Riche D., Maziere M., Hantraye P Chronic MPTP treatment reproduces in baboons the differential vulnerability of mesencephalic dopaminergic neurons observed in Parkinson's disease. Neuroscience 1994, 63:47-56.
-
(1994)
Neuroscience
, vol.63
, pp. 47-56
-
-
Varastet, M.1
Riche, D.2
Maziere, M.3
Hantraye, P.4
-
233
-
-
33749453510
-
Parkin protects against neurotoxicity in the 6-hydroxydopamine rat model for Parkinson's disease. Molecular therapy
-
Vercammen L., Van der Perren A., Vaudano E., Gijsbers R., Debyser Z., Van den Haute C., Baekelandt V. Parkin protects against neurotoxicity in the 6-hydroxydopamine rat model for Parkinson's disease. Molecular therapy. The Journal of the American Society of Gene Therapy 2006, 14:716-723.
-
(2006)
The Journal of the American Society of Gene Therapy
, vol.14
, pp. 716-723
-
-
Vercammen, L.1
Van der Perren, A.2
Vaudano, E.3
Gijsbers, R.4
Debyser, Z.5
Van den Haute, C.6
Baekelandt, V.7
-
234
-
-
0036297660
-
Sequence analysis of the entire mitochondrial genome in Parkinson's disease
-
Vives-Bauza C., Andreu A.L., Manfredi G., Beal M.F., Janetzky B., Gruenewald T.H., Lin M.T. Sequence analysis of the entire mitochondrial genome in Parkinson's disease. Biochemical and Biophysical Research Communications 2002, 290:1593-1601.
-
(2002)
Biochemical and Biophysical Research Communications
, vol.290
, pp. 1593-1601
-
-
Vives-Bauza, C.1
Andreu, A.L.2
Manfredi, G.3
Beal, M.F.4
Janetzky, B.5
Gruenewald, T.H.6
Lin, M.T.7
-
235
-
-
33745143950
-
Inhibitory effects of pesticides on proteasome activity: implication in Parkinson's disease
-
Bronstein JM
-
Wang X.F., Li S., Chou A.P., Bronstein JM Inhibitory effects of pesticides on proteasome activity: implication in Parkinson's disease. Neurobiology of Disease 2006, 23:198-205.
-
(2006)
Neurobiology of Disease
, vol.23
, pp. 198-205
-
-
Wang, X.F.1
Li, S.2
Chou, A.P.3
-
236
-
-
35349030746
-
PINK1 mutants associated with recessive Parkinson's disease are defective in inhibiting mitochondrial release of cytochrome c
-
Wang H.L., Chou A.H., Yeh T.H., Li A.H., Chen Y.L., Kuo Y.L., Tsai S.R., Yu S.T. PINK1 mutants associated with recessive Parkinson's disease are defective in inhibiting mitochondrial release of cytochrome c. Neurobiology of Disease 2007, 28:216-226.
-
(2007)
Neurobiology of Disease
, vol.28
, pp. 216-226
-
-
Wang, H.L.1
Chou, A.H.2
Yeh, T.H.3
Li, A.H.4
Chen, Y.L.5
Kuo, Y.L.6
Tsai, S.R.7
Yu, S.T.8
-
237
-
-
79954616687
-
PARK6 PINK1 mutants are defective in maintaining mitochondrial membrane potential and inhibiting ROS formation of substantia nigra dopaminergic neurons
-
Wang H.L., Chou A.H., Wu A.S., Chen S.Y., Weng Y.H., Kao Y.C., Yeh T.H., Chu P.J., Lu C.S. PARK6 PINK1 mutants are defective in maintaining mitochondrial membrane potential and inhibiting ROS formation of substantia nigra dopaminergic neurons. Biochimica et Biophysica Acta 2011, 1812:674-684.
-
(2011)
Biochimica et Biophysica Acta
, vol.1812
, pp. 674-684
-
-
Wang, H.L.1
Chou, A.H.2
Wu, A.S.3
Chen, S.Y.4
Weng, Y.H.5
Kao, Y.C.6
Yeh, T.H.7
Chu, P.J.8
Lu, C.S.9
-
238
-
-
84863164994
-
Phosphorylated alpha-synuclein in Parkinson's disease
-
Wang Y., Shi M., Chung K.A., Zabetian C.P., Leverenz J.B., Berg D., Srulijes K., Trojanowski J.Q., Lee V.M., Siderowf A.D., Hurtig H., Litvan I., Schiess M.C., Peskind E.R., Masuda M., Hasegawa M., Lin X., Pan C., Galasko D., Goldstein D.S., Jensen P.H., Yang H., Cain K.C., Zhang J. Phosphorylated alpha-synuclein in Parkinson's disease. Science Translational Medicine 2012, 121(4):ra120.
-
(2012)
Science Translational Medicine
, vol.121
, Issue.4
-
-
Wang, Y.1
Shi, M.2
Chung, K.A.3
Zabetian, C.P.4
Leverenz, J.B.5
Berg, D.6
Srulijes, K.7
Trojanowski, J.Q.8
Lee, V.M.9
Siderowf, A.D.10
Hurtig, H.11
Litvan, I.12
Schiess, M.C.13
Peskind, E.R.14
Masuda, M.15
Hasegawa, M.16
Lin, X.17
Pan, C.18
Galasko, D.19
Goldstein, D.S.20
Jensen, P.H.21
Yang, H.22
Cain, K.C.23
Zhang, J.24
more..
-
239
-
-
79955528923
-
Alternative mitochondrial electron transfer as a novel strategy for neuroprotection
-
Wen Y., Li W., Poteet E.C., Xie L., Tan C., Yan L.J., Ju X., Liu R., Qian H., Marvin M.A., Goldberg M.S., She H., Mao Z., Simpkins J.W., Yang S.H. Alternative mitochondrial electron transfer as a novel strategy for neuroprotection. The Journal of Biological Chemistry 2011, 286:16504-16515.
-
(2011)
The Journal of Biological Chemistry
, vol.286
, pp. 16504-16515
-
-
Wen, Y.1
Li, W.2
Poteet, E.C.3
Xie, L.4
Tan, C.5
Yan, L.J.6
Ju, X.7
Liu, R.8
Qian, H.9
Marvin, M.A.10
Goldberg, M.S.11
She, H.12
Mao, Z.13
Simpkins, J.W.14
Yang, S.H.15
-
240
-
-
28044460070
-
Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity
-
West A.B., Moore D.J., Biskup S., Bugayenko A., Smith W.W., Ross C.A., Dawson V.L., Dawson T.M. Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity. Proceedings of the National Academy of Sciences of the United States of America 2005, 102:16842-16847.
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, pp. 16842-16847
-
-
West, A.B.1
Moore, D.J.2
Biskup, S.3
Bugayenko, A.4
Smith, W.W.5
Ross, C.A.6
Dawson, V.L.7
Dawson, T.M.8
-
241
-
-
0034118103
-
Coupled oscillator model of the dopaminergic neuron of the substantia nigra
-
Wilson C.J., Callaway J.C. Coupled oscillator model of the dopaminergic neuron of the substantia nigra. Journal of Neurophysiology 2000, 83:3084-3100.
-
(2000)
Journal of Neurophysiology
, vol.83
, pp. 3084-3100
-
-
Wilson, C.J.1
Callaway, J.C.2
-
243
-
-
38549169530
-
The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases
-
Winklhofer K.F., Tatzelt J., Haass C. The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases. The EMBO Journal 2008, 27:336-349.
-
(2008)
The EMBO Journal
, vol.27
, pp. 336-349
-
-
Winklhofer, K.F.1
Tatzelt, J.2
Haass, C.3
-
244
-
-
49349087497
-
PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons
-
Wood-Kaczmar A., Gandhi S., Yao Z., Abramov A.Y., Miljan E.A., Keen G., Stanyer L., Hargreaves I., Klupsch K., Deas E., Downward J., Mansfield L., Jat P., Taylor J., Heales S., Duchen M.R., Latchman D., Tabrizi S.J., Wood N.W. PINK1 is necessary for long term survival and mitochondrial function in human dopaminergic neurons. PloS One 2008, 3:e2455.
-
(2008)
PloS One
, vol.3
-
-
Wood-Kaczmar, A.1
Gandhi, S.2
Yao, Z.3
Abramov, A.Y.4
Miljan, E.A.5
Keen, G.6
Stanyer, L.7
Hargreaves, I.8
Klupsch, K.9
Deas, E.10
Downward, J.11
Mansfield, L.12
Jat, P.13
Taylor, J.14
Heales, S.15
Duchen, M.R.16
Latchman, D.17
Tabrizi, S.J.18
Wood, N.W.19
-
245
-
-
84867234462
-
Central nervous system damage due to acute paraquat poisoning: a neuroimaging study with 3.0T MRI
-
Wu B.L., Song B., Tian S.Z., Huo S.H., Cui C.X., Guo Y.S., Liu H.J. Central nervous system damage due to acute paraquat poisoning: a neuroimaging study with 3.0T MRI. Neurotoxicology 2012, 33(5):1330-1337.
-
(2012)
Neurotoxicology
, vol.33
, Issue.5
, pp. 1330-1337
-
-
Wu, B.L.1
Song, B.2
Tian, S.Z.3
Huo, S.H.4
Cui, C.X.5
Guo, Y.S.6
Liu, H.J.7
-
246
-
-
28844448703
-
The bipyridyl herbicide paraquat produces oxidative stress-mediated toxicity in human neuroblastoma SH-SY5Y cells: relevance to the dopaminergic pathogenesis
-
Yang W., Tiffany-Castiglioni E. The bipyridyl herbicide paraquat produces oxidative stress-mediated toxicity in human neuroblastoma SH-SY5Y cells: relevance to the dopaminergic pathogenesis. Journal of Toxicology and Environmental Health Part A 2005, 68:1939-1961.
-
(2005)
Journal of Toxicology and Environmental Health Part A
, vol.68
, pp. 1939-1961
-
-
Yang, W.1
Tiffany-Castiglioni, E.2
-
247
-
-
33746080412
-
Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin
-
Yang Y., Gehrke S., Imai Y., Huang Z., Ouyang Y., Wang J.W., Yang L., Beal M.F., Vogel H., Lu B. Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin. Proceedings of the National Academy of Sciences of the United States of America 2006, 103:10793-10798.
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, pp. 10793-10798
-
-
Yang, Y.1
Gehrke, S.2
Imai, Y.3
Huang, Z.4
Ouyang, Y.5
Wang, J.W.6
Yang, L.7
Beal, M.F.8
Vogel, H.9
Lu, B.10
-
248
-
-
35748954034
-
Paraquat induces dopaminergic dysfunction and proteasome impairment in DJ-1-deficient mice
-
Yang W., Chen L., Ding Y., Zhuang X., Kang U.J. Paraquat induces dopaminergic dysfunction and proteasome impairment in DJ-1-deficient mice. Human Molecular Genetics 2007, 16:2900-2910.
-
(2007)
Human Molecular Genetics
, vol.16
, pp. 2900-2910
-
-
Yang, W.1
Chen, L.2
Ding, Y.3
Zhuang, X.4
Kang, U.J.5
-
249
-
-
44349195101
-
Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery
-
Yang Y., Ouyang Y., Yang L., Beal M.F., McQuibban A., Vogel H., Lu B. Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery. Proceedings of the National Academy of Sciences of the United States of America 2008, 105:7070-7075.
-
(2008)
Proceedings of the National Academy of Sciences of the United States of America
, vol.105
, pp. 7070-7075
-
-
Yang, Y.1
Ouyang, Y.2
Yang, L.3
Beal, M.F.4
McQuibban, A.5
Vogel, H.6
Lu, B.7
-
250
-
-
0345357664
-
Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition
-
Yokota T., Sugawara K., Ito K., Takahashi R., Ariga H., Mizusawa H. Down regulation of DJ-1 enhances cell death by oxidative stress, ER stress, and proteasome inhibition. Biochemical and Biophysical Research Communications 2003, 312:1342-1348.
-
(2003)
Biochemical and Biophysical Research Communications
, vol.312
, pp. 1342-1348
-
-
Yokota, T.1
Sugawara, K.2
Ito, K.3
Takahashi, R.4
Ariga, H.5
Mizusawa, H.6
-
251
-
-
0026544129
-
Mitochondrial complex I and II activities of lymphocytes and platelets in Parkinson's disease
-
Yoshino H., Nakagawa-Hattori Y., Kondo T., Mizuno Y. Mitochondrial complex I and II activities of lymphocytes and platelets in Parkinson's disease. Journal of Neural Transmission Parkinson's Disease and Dementia Section 1992, 4:27-34.
-
(1992)
Journal of Neural Transmission Parkinson's Disease and Dementia Section
, vol.4
, pp. 27-34
-
-
Yoshino, H.1
Nakagawa-Hattori, Y.2
Kondo, T.3
Mizuno, Y.4
-
252
-
-
79960826207
-
The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons
-
Yu W., Sun Y., Guo S., Lu B. The PINK1/Parkin pathway regulates mitochondrial dynamics and function in mammalian hippocampal and dopaminergic neurons. Human Molecular Genetics 2011, 20:3227-3240.
-
(2011)
Human Molecular Genetics
, vol.20
, pp. 3227-3240
-
-
Yu, W.1
Sun, Y.2
Guo, S.3
Lu, B.4
-
253
-
-
0036235608
-
Paraquat- and diquat-induced oxygen radical generation and lipid peroxidation in rat brain microsomes
-
Yumino K., Kawakami I., Tamura M., Hayashi T., Nakamura M. Paraquat- and diquat-induced oxygen radical generation and lipid peroxidation in rat brain microsomes. Journal of Biochemistry 2002, 131:565-570.
-
(2002)
Journal of Biochemistry
, vol.131
, pp. 565-570
-
-
Yumino, K.1
Kawakami, I.2
Tamura, M.3
Hayashi, T.4
Nakamura, M.5
-
254
-
-
10744230149
-
The new mutation E46K, of alpha-synuclein causes Parkinson and Lewy body dementia
-
Zarranz J.J., Alegre J., Gomez-Esteban J.C., Lezcano E., Ros R., Ampuero I., Vidal L., Hoenicka J., Rodriguez O., Atares B., Llorens V., Gomez Tortosa E., del Ser T., Munoz D.G., de Yebenes J.G. The new mutation E46K, of alpha-synuclein causes Parkinson and Lewy body dementia. Annals of Neurology 2004, 55:164-173.
-
(2004)
Annals of Neurology
, vol.55
, pp. 164-173
-
-
Zarranz, J.J.1
Alegre, J.2
Gomez-Esteban, J.C.3
Lezcano, E.4
Ros, R.5
Ampuero, I.6
Vidal, L.7
Hoenicka, J.8
Rodriguez, O.9
Atares, B.10
Llorens, V.11
Gomez Tortosa, E.12
del Ser, T.13
Munoz, D.G.14
de Yebenes, J.G.15
-
255
-
-
0037265974
-
Manganese ethylene-bis-dithiocarbamate and selective dopaminergic neurodegeneration in rat: a link through mitochondrial dysfunction
-
Zhang J., Fitsanakis V.A., Gu G., Jing D., Ao M., Amarnath V., Montine T.J. Manganese ethylene-bis-dithiocarbamate and selective dopaminergic neurodegeneration in rat: a link through mitochondrial dysfunction. Journal of Neurochemistry 2003, 84:336-346.
-
(2003)
Journal of Neurochemistry
, vol.84
, pp. 336-346
-
-
Zhang, J.1
Fitsanakis, V.A.2
Gu, G.3
Jing, D.4
Ao, M.5
Amarnath, V.6
Montine, T.J.7
-
256
-
-
24944534660
-
Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis
-
Zhang L., Shimoji M., Thomas B., Moore D.J., Yu S.W., Marupudi N.I., Torp R., Torgner I.A., Ottersen O.P., Dawson T.M., Dawson V.L. Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis. Human Molecular Genetics 2005, 14:2063-2073.
-
(2005)
Human Molecular Genetics
, vol.14
, pp. 2063-2073
-
-
Zhang, L.1
Shimoji, M.2
Thomas, B.3
Moore, D.J.4
Yu, S.W.5
Marupudi, N.I.6
Torp, R.7
Torgner, I.A.8
Ottersen, O.P.9
Dawson, T.M.10
Dawson, V.L.11
-
257
-
-
56049093847
-
Semi-quantitative analysis of alpha-synuclein in subcellular pools of rat brain neurons: an immunogold electron microscopic study using a C-terminal specific monoclonal antibody
-
Zhang L., Zhang C., Zhu Y., Cai Q., Chan P., Ueda K., Yu S., Yang H. Semi-quantitative analysis of alpha-synuclein in subcellular pools of rat brain neurons: an immunogold electron microscopic study using a C-terminal specific monoclonal antibody. Brain Research 2008, 1244:40-52.
-
(2008)
Brain Research
, vol.1244
, pp. 40-52
-
-
Zhang, L.1
Zhang, C.2
Zhu, Y.3
Cai, Q.4
Chan, P.5
Ueda, K.6
Yu, S.7
Yang, H.8
-
258
-
-
77949865344
-
Region-specific protein abundance changes in the brain of MPTP-induced Parkinson's disease mouse model
-
Zhang X., Zhou J.Y., Chin M.H., Schepmoes A.A., Petyuk V.A., Weitz K.K., Petritis B.O., Monroe M.E., Camp D.G., Wood S.A., Melega W.P., Bigelow D.J., Smith D.J., Qian W.J., Smith R.D. Region-specific protein abundance changes in the brain of MPTP-induced Parkinson's disease mouse model. Journal of Proteome Research 2010, 9:1496-1509.
-
(2010)
Journal of Proteome Research
, vol.9
, pp. 1496-1509
-
-
Zhang, X.1
Zhou, J.Y.2
Chin, M.H.3
Schepmoes, A.A.4
Petyuk, V.A.5
Weitz, K.K.6
Petritis, B.O.7
Monroe, M.E.8
Camp, D.G.9
Wood, S.A.10
Melega, W.P.11
Bigelow, D.J.12
Smith, D.J.13
Qian, W.J.14
Smith, R.D.15
-
259
-
-
54449096831
-
Synergistic activation of the human MnSOD promoter by DJ-1 and PGC-1alpha: regulation by SUMOylation and oxidation
-
Zhong N., Xu J. Synergistic activation of the human MnSOD promoter by DJ-1 and PGC-1alpha: regulation by SUMOylation and oxidation. Human Molecular Genetics 2008, 17:3357-3367.
-
(2008)
Human Molecular Genetics
, vol.17
, pp. 3357-3367
-
-
Zhong, N.1
Xu, J.2
-
260
-
-
4444225471
-
Proteasomal inhibition induced by manganese ethylene-bis-dithiocarbamate: relevance to Parkinson's disease
-
Zhou Y., Shie F.S., Piccardo P., Montine T.J., Zhang J. Proteasomal inhibition induced by manganese ethylene-bis-dithiocarbamate: relevance to Parkinson's disease. Neuroscience 2004, 128:281-291.
-
(2004)
Neuroscience
, vol.128
, pp. 281-291
-
-
Zhou, Y.1
Shie, F.S.2
Piccardo, P.3
Montine, T.J.4
Zhang, J.5
-
261
-
-
4644263680
-
Variable effects of chronic subcutaneous administration of rotenone on striatal histology
-
Zhu C., Vourc'h P., Fernagut P.O., Fleming S.M., Lacan S., Dicarlo C.D., Seaman R.L., Chesselet M.F. Variable effects of chronic subcutaneous administration of rotenone on striatal histology. The Journal of Comparative Neurology 2004, 478:418-426.
-
(2004)
The Journal of Comparative Neurology
, vol.478
, pp. 418-426
-
-
Zhu, C.1
Vourc'h, P.2
Fernagut, P.O.3
Fleming, S.M.4
Lacan, S.5
Dicarlo, C.D.6
Seaman, R.L.7
Chesselet, M.F.8
-
262
-
-
8844233579
-
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology
-
Zimprich A., Biskup S., Leitner P., Lichtner P., Farrer M., Lincoln S., Kachergus J., Hulihan M., Uitti R.J., Calne D.B., Stoessl A.J., Pfeiffer R.F., Patenge N., Carbajal I.C., Vieregge P., Asmus F., Muller-Myhsok B., Dickson D.W., Meitinger T., Strom T.M., Wszolek Z.K., Gasser T. Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology. Neuron 2004, 44:601-607.
-
(2004)
Neuron
, vol.44
, pp. 601-607
-
-
Zimprich, A.1
Biskup, S.2
Leitner, P.3
Lichtner, P.4
Farrer, M.5
Lincoln, S.6
Kachergus, J.7
Hulihan, M.8
Uitti, R.J.9
Calne, D.B.10
Stoessl, A.J.11
Pfeiffer, R.F.12
Patenge, N.13
Carbajal, I.C.14
Vieregge, P.15
Asmus, F.16
Muller-Myhsok, B.17
Dickson, D.W.18
Meitinger, T.19
Strom, T.M.20
Wszolek, Z.K.21
Gasser, T.22
more..
-
263
-
-
77955276765
-
Mitochondrial fusion proteins: dual regulators of morphology and metabolism
-
Zorzano A., Liesa M., Sebastian D., Segales J., Palacin M. Mitochondrial fusion proteins: dual regulators of morphology and metabolism. Seminars in Cell & DevelopmentalB 2010, 21:566-574.
-
(2010)
Seminars in Cell & DevelopmentalB
, vol.21
, pp. 566-574
-
-
Zorzano, A.1
Liesa, M.2
Sebastian, D.3
Segales, J.4
Palacin, M.5
|