Early biochemical and morphological modifications in the brain of a transgenic mouse model of Alzheimer's disease: A role for peroxisomes

Journal of Alzheimer's Disease

Volumn 18, Issue 4, 2009, Pages 935-952

  Cimini, Annamaria ^a   Moreno, Sandra ^b   D'Amelio, Marcello ^c   Cristiano, Loredana ^a   D'Angelo, Barbara ^a   Falone, Stefano ^a   Benedetti, Elisabetta ^a   Carrara, Paolo ^b   Fanelli, Francesca ^b   Cecconi, Francesco ^c,d   Amicarelli, Fernanda ^a   Cerù, Maria Paola ^a  

^a UNIVERSITY OF L'AQUILA   (Italy)

^b ROMA TRE UNIVERSITY   (Italy)

^c IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^d UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Acyl CoA oxidation; Alzheimer's disease; Antioxidant enzymes; Catalase; Hippocampus; Neocortex; Oxidative stress; Peroxisomes; Reactive oxygen species; Tg2576

Indexed keywords

ACETYL COENZYME A ACYLTRANSFERASE; ACYL COENZYME A OXIDASE; AMYLOID BETA PROTEIN; CATALASE; COPPER ZINC SUPEROXIDE DISMUTASE; GLUTATHIONE PEROXIDASE; MANGANESE SUPEROXIDE DISMUTASE; MEMBRANE PROTEIN; MESSENGER RNA; PEROXIN 5; REACTIVE OXYGEN METABOLITE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; FATTY ACID OXIDATION; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; MORPHOLOGY; MOUSE; NEOCORTEX; NEUROLOGIC DISEASE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PEROXISOME; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRANSGENIC MOUSE; WESTERN BLOTTING;

EID: 74949133060     PISSN: 13872877     EISSN: None     Source Type: Journal    
DOI: 10.3233/JAD-2009-1199     Document Type: Article

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