메뉴 건너뛰기




Volumn 84, Issue 5, 2006, Pages 1098-1106

Production of nerve growth factor by β-amyloid-stimulated astrocytes induces p75NTR-dependent tau hyperphosphorylation in cultured hippocampal neurons

Author keywords

Alzheimer's disease; Apoptosis; Astrocytes; NGF; p75 neurotrophin receptor

Indexed keywords

AMYLOID BETA PROTEIN[25-35]; CASPASE INHIBITOR; NERVE GROWTH FACTOR; NEUROTROPHIN RECEPTOR; NITRIC OXIDE; PROTEIN P75; TAU PROTEIN;

EID: 33749534896     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.20996     Document Type: Article
Times cited : (48)

References (72)
  • 1
    • 0034678024 scopus 로고    scopus 로고
    • Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1beta- and tumor necrosis factor-alpha (TNFalpha)-dependent, and involves a TNFalpha receptor-associated factor- and NFkappaB-inducing kinase-dependent signaling mechanism
    • Akama KT, Van Eldik LJ. 2000. Beta-amyloid stimulation of inducible nitric-oxide synthase in astrocytes is interleukin-1beta- and tumor necrosis factor-alpha (TNFalpha)-dependent, and involves a TNFalpha receptor-associated factor- and NFkappaB-inducing kinase-dependent signaling mechanism. J Biol Chem 275:7918-7924.
    • (2000) J Biol Chem , vol.275 , pp. 7918-7924
    • Akama, K.T.1    Van Eldik, L.J.2
  • 2
    • 0032859938 scopus 로고    scopus 로고
    • Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloid-induced neuronal death
    • Alvarez A, Toro R, Caceres A, Maccioni RB. 1999. Inhibition of tau phosphorylating protein kinase cdk5 prevents beta-amyloid-induced neuronal death. FEBS Lett 459:421-426.
    • (1999) FEBS Lett , vol.459 , pp. 421-426
    • Alvarez, A.1    Toro, R.2    Caceres, A.3    Maccioni, R.B.4
  • 3
    • 0035298135 scopus 로고    scopus 로고
    • A Cdk5-p35 stable complex is involved in the beta-amyloid-induced deregulation of Cdk5 activity in hippocampal neurons
    • Alvarez A, Muñoz JP, Maccioni RB. 2001. A Cdk5-p35 stable complex is involved in the beta-amyloid-induced deregulation of Cdk5 activity in hippocampal neurons. Exp Cell Res 264:266-274.
    • (2001) Exp Cell Res , vol.264 , pp. 266-274
    • Alvarez, A.1    Muñoz, J.P.2    Maccioni, R.B.3
  • 6
    • 0017350927 scopus 로고
    • Rat hippocampal neurons in dispersed cell culture
    • Banker G, Cowan W. 1977. Rat hippocampal neurons in dispersed cell culture. Brain Res 126:397-342.
    • (1977) Brain Res , vol.126 , pp. 397-1342
    • Banker, G.1    Cowan, W.2
  • 7
    • 0033951624 scopus 로고    scopus 로고
    • The p75 neurotrophin receptor and neuronal apoptosis
    • Barrett GL. 2000. The p75 neurotrophin receptor and neuronal apoptosis. Prog Neurobiol 61:205-229.
    • (2000) Prog Neurobiol , vol.61 , pp. 205-229
    • Barrett, G.L.1
  • 8
    • 0031148892 scopus 로고    scopus 로고
    • Decreased TrkA gene expression in cholinergic neurons of the striatum and basal forebrain of patients with Alzheimer's disease
    • Boissiere F, Faucheux B, Ruberg M, Agid Y, Hirsch EC. 1997. Decreased TrkA gene expression in cholinergic neurons of the striatum and basal forebrain of patients with Alzheimer's disease. Exp Neurol 145:245-252.
    • (1997) Exp Neurol , vol.145 , pp. 245-252
    • Boissiere, F.1    Faucheux, B.2    Ruberg, M.3    Agid, Y.4    Hirsch, E.C.5
  • 9
    • 0028785525 scopus 로고
    • Interaction of tau with the neuronal plasma membrane mediated by tau's amino-terminal projection domain
    • Brandt R, Leger J, Lee G. 1995. Interaction of tau with the neuronal plasma membrane mediated by tau's amino-terminal projection domain. J Cell Biol 131:1327-1340.
    • (1995) J Cell Biol , vol.131 , pp. 1327-1340
    • Brandt, R.1    Leger, J.2    Lee, G.3
  • 10
    • 33749523135 scopus 로고    scopus 로고
    • Activated neuroglia in Alzheimer's disease
    • De Vellis JS, editor. Totowa, NJ: Humana Press
    • Brunden KR, Frederickson RCA. 2002. Activated neuroglia in Alzheimer's disease. In: De Vellis JS, editor. Neuroglia in the aging brain. Totowa, NJ: Humana Press, p 365-374.
    • (2002) Neuroglia in the Aging Brain , pp. 365-374
    • Brunden, K.R.1    Frederickson, R.C.A.2
  • 11
    • 0023689626 scopus 로고
    • Differential expression of the nerve growth factor receptor gene in multiple brain areas
    • Buck CR, Martinez HJ, Chao MV, Black IB. 1988. Differential expression of the nerve growth factor receptor gene in multiple brain areas. Brain Res Dev Brain Res 44:259-268.
    • (1988) Brain Res Dev Brain Res , vol.44 , pp. 259-268
    • Buck, C.R.1    Martinez, H.J.2    Chao, M.V.3    Black, I.B.4
  • 12
    • 0036319594 scopus 로고    scopus 로고
    • p75 neurotrophin receptor is required for constitutive and NGF-induced survival signalling in PC12 cells and rat hippocampal neurones
    • Bui NT, Konig HG, Culmsee C, Bauerbach E, Poppe M, Krieglstein J, Prehn JH. 2002. p75 Neurotrophin receptor is required for constitutive and NGF-induced survival signalling in PC12 cells and rat hippocampal neurones. J Neurochem 81:594-605.
    • (2002) J Neurochem , vol.81 , pp. 594-605
    • Bui, N.T.1    Konig, H.G.2    Culmsee, C.3    Bauerbach, E.4    Poppe, M.5    Krieglstein, J.6    Prehn, J.H.7
  • 14
    • 0037762690 scopus 로고    scopus 로고
    • Neurotrophins and their receptors: A convergence point form many signalling pathways
    • Chao MV. 2003. Neurotrophins and their receptors: a convergence point form many signalling pathways. Nat Rev Neurosci 4:299-309.
    • (2003) Nat Rev Neurosci , vol.4 , pp. 299-309
    • Chao, M.V.1
  • 16
  • 17
    • 0027173094 scopus 로고
    • A tau-like protein interacts with stress fibers and microtubules in human and rodent cultured cell lines
    • Cross D, Vial C, Maccioni RB. 1993. A tau-like protein interacts with stress fibers and microtubules in human and rodent cultured cell lines. J Cell Sci 105:51-60.
    • (1993) J Cell Sci , vol.105 , pp. 51-60
    • Cross, D.1    Vial, C.2    Maccioni, R.B.3
  • 18
    • 0030589578 scopus 로고    scopus 로고
    • Tau-like proteins associated with centrosomes in cultured cells
    • Cross D, Tapia L, Garrido J, Maccioni RB. 1996. Tau-like proteins associated with centrosomes in cultured cells. Exp Cell Res 229:378-387.
    • (1996) Exp Cell Res , vol.229 , pp. 378-387
    • Cross, D.1    Tapia, L.2    Garrido, J.3    Maccioni, R.B.4
  • 19
    • 0027197191 scopus 로고
    • Detection of NGF-like activity in human brain tissue: Increased levels in Alzheimer's disease
    • Crutcher KA, Scott SA, Liang S, Everson WV, Weingartner J. 1993. Detection of NGF-like activity in human brain tissue: increased levels in Alzheimer's disease. J Neurosci 13:2540-2550.
    • (1993) J Neurosci , vol.13 , pp. 2540-2550
    • Crutcher, K.A.1    Scott, S.A.2    Liang, S.3    Everson, W.V.4    Weingartner, J.5
  • 20
    • 0037121659 scopus 로고    scopus 로고
    • Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75
    • Culmsee C, Gerling N, Lehmann M, Nikolova-Karakashian M, Prehn JH, Mattson MP, Krieglstein J. 2002. Nerve growth factor survival signaling in cultured hippocampal neurons is mediated through TrkA and requires the common neurotrophin receptor P75. Neuroscience 115:1089-1108.
    • (2002) Neuroscience , vol.115 , pp. 1089-1108
    • Culmsee, C.1    Gerling, N.2    Lehmann, M.3    Nikolova-Karakashian, M.4    Prehn, J.H.5    Mattson, M.P.6    Krieglstein, J.7
  • 21
    • 0018938926 scopus 로고
    • Glial fibrillary acidic protein and Alzheimer-type senile dementia
    • Duffy PE, Rapport M, Graf L. 1980. Glial fibrillary acidic protein and Alzheimer-type senile dementia. Neurology 30:778-782.
    • (1980) Neurology , vol.30 , pp. 778-782
    • Duffy, P.E.1    Rapport, M.2    Graf, L.3
  • 22
    • 0025096474 scopus 로고
    • Cholinergic neurons of the nucleus basalis express elevated levels of nerve growth factor receptor mRNA in senile dementia of the Alzheimer's type
    • Ernfors P, Lindefors N, Chan-Palay V, Persson H. 1990. Cholinergic neurons of the nucleus basalis express elevated levels of nerve growth factor receptor mRNA in senile dementia of the Alzheimer's type. Dementia 1:138-145.
    • (1990) Dementia , vol.1 , pp. 138-145
    • Ernfors, P.1    Lindefors, N.2    Chan-Palay, V.3    Persson, H.4
  • 23
    • 0030297659 scopus 로고    scopus 로고
    • Nerve growth factor mRNA and protein levels measured in the same tissue from normal and Alzheimer's disease parietal cortex
    • Fahnestock M, Scott SA, Jette N, Weingartner JA, Crutcher KA. 1996. Nerve growth factor mRNA and protein levels measured in the same tissue from normal and Alzheimer's disease parietal cortex. Brain Res Mol Brain Res 42:175-178.
    • (1996) Brain Res Mol Brain Res , vol.42 , pp. 175-178
    • Fahnestock, M.1    Scott, S.A.2    Jette, N.3    Weingartner, J.A.4    Crutcher, K.A.5
  • 24
    • 0034848604 scopus 로고    scopus 로고
    • The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease
    • Fahnestock M, Michalski B, Xu B, Conghlim M. 2001. The precursor pro-nerve growth factor is the predominant form of nerve growth factor in brain and is increased in Alzheimer's disease. Mol Cel Neurosci 18:210-220.
    • (2001) Mol Cel Neurosci , vol.18 , pp. 210-220
    • Fahnestock, M.1    Michalski, B.2    Xu, B.3    Conghlim, M.4
  • 25
    • 0023643241 scopus 로고
    • Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor
    • Fischer W, Wictorin K, Bjorklund A, Williams LR, Varon S, Gage FH. 1987. Amelioration of cholinergic neuron atrophy and spatial memory impairment in aged rats by nerve growth factor. Nature 329:65-68.
    • (1987) Nature , vol.329 , pp. 65-68
    • Fischer, W.1    Wictorin, K.2    Bjorklund, A.3    Williams, L.R.4    Varon, S.5    Gage, F.H.6
  • 26
    • 0026589735 scopus 로고
    • Astroglia in Alzheimer's disease
    • Frederickson RC. 1992. Astroglia in Alzheimer's disease. Neurobiol Aging 13:239-253.
    • (1992) Neurobiol Aging , vol.13 , pp. 239-253
    • Frederickson, R.C.1
  • 27
    • 0034279150 scopus 로고    scopus 로고
    • Neurotrophins induce death of hippocampal neurons via the p75 receptor
    • Friedman WJ. 2000. Neurotrophins induce death of hippocampal neurons via the p75 receptor. J Neurosci 20:6340-6346.
    • (2000) J Neurosci , vol.20 , pp. 6340-6346
    • Friedman, W.J.1
  • 28
    • 0030846224 scopus 로고    scopus 로고
    • Regulation of nerve growth factor secretion and mRNA expression by bacterial lipopolysaccharide in primary cultures of rat astrocytes
    • Galve-Roperh I, Malpartida JM, Haro A, Brachet P, Diaz-Laviada I. 1997. Regulation of nerve growth factor secretion and mRNA expression by bacterial lipopolysaccharide in primary cultures of rat astrocytes. J Neurosci Res 49:569-575.
    • (1997) J Neurosci Res , vol.49 , pp. 569-575
    • Galve-Roperh, I.1    Malpartida, J.M.2    Haro, A.3    Brachet, P.4    Diaz-Laviada, I.5
  • 29
    • 0037096193 scopus 로고    scopus 로고
    • The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's disease
    • Giasson BI, Ischiroupulos H, Lee VM, Trojanowsky JQ. 2002. The relationship between oxidative/nitrative stress and pathological inclusions in Alzheimer's and Parkinson's disease. Free Rad Biol Med 32:1264-1275.
    • (2002) Free Rad Biol Med , vol.32 , pp. 1264-1275
    • Giasson, B.I.1    Ischiroupulos, H.2    Lee, V.M.3    Trojanowsky, J.Q.4
  • 30
    • 33645301867 scopus 로고    scopus 로고
    • Down regulation of trk but not p75 gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease
    • Ginsberg SD, Che S, Wuu J, Counts SE, Mufson EJ. 2006. Down regulation of trk but not p75 gene expression in single cholinergic basal forebrain neurons mark the progression of Alzheimer's disease. J Neurochem 97:475-487.
    • (2006) J Neurochem , vol.97 , pp. 475-487
    • Ginsberg, S.D.1    Che, S.2    Wuu, J.3    Counts, S.E.4    Mufson, E.J.5
  • 31
    • 0024504222 scopus 로고
    • Nerve growth factor receptor mRNA distribution in human brain: Normal levels in basal forebrain in Alzheimer's disease
    • Goedert M, Fine A, Dawbarn D, Wilcock GK, Chao MV. 1989. Nerve growth factor receptor mRNA distribution in human brain: normal levels in basal forebrain in Alzheimer's disease. Brain Res Mol Brain Res 5:1-7.
    • (1989) Brain Res Mol Brain Res , vol.5 , pp. 1-7
    • Goedert, M.1    Fine, A.2    Dawbarn, D.3    Wilcock, G.K.4    Chao, M.V.5
  • 32
    • 0032531735 scopus 로고    scopus 로고
    • Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation
    • Hensley K, Maidt ML, Yu Z, Sang H, Markesbery WR, Floyd RA. 1998. Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation. J Neurosci 18:8126-8132.
    • (1998) J Neurosci , vol.18 , pp. 8126-8132
    • Hensley, K.1    Maidt, M.L.2    Yu, Z.3    Sang, H.4    Markesbery, W.R.5    Floyd, R.A.6
  • 33
    • 0032579285 scopus 로고    scopus 로고
    • Decreased trkA neurotrophin receptor expression in the parietal cortex of patients with Alzheimer's disease
    • Hock C, Heese K, Muller-Spahn F, Hulette C, Rosenberg C, Otten U. 1998. Decreased trkA neurotrophin receptor expression in the parietal cortex of patients with Alzheimer's disease. Neurosci Lett 241:151-154.
    • (1998) Neurosci Lett , vol.241 , pp. 151-154
    • Hock, C.1    Heese, K.2    Muller-Spahn, F.3    Hulette, C.4    Rosenberg, C.5    Otten, U.6
  • 34
    • 0034087784 scopus 로고    scopus 로고
    • Region-specific neurotrophin imbalances in Alzheimer disease: Decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas
    • Hock C, Heese K, Hulette C, Rosenberg C, Otten U. 2000. Region-specific neurotrophin imbalances in Alzheimer disease: decreased levels of brain-derived neurotrophic factor and increased levels of nerve growth factor in hippocampus and cortical areas. Arch Neurol 57:846-851.
    • (2000) Arch Neurol , vol.57 , pp. 846-851
    • Hock, C.1    Heese, K.2    Hulette, C.3    Rosenberg, C.4    Otten, U.5
  • 35
    • 0032473596 scopus 로고    scopus 로고
    • Amyloid-beta peptide activates cultured astrocytes: Morphological alterations, cytokine induction and nitric oxide release
    • Hu J, Akama KT, Krafft GA, Chromy BA, Van Eldik LJ. 1998. Amyloid-beta peptide activates cultured astrocytes: morphological alterations, cytokine induction and nitric oxide release. Brain Res 785:195-206.
    • (1998) Brain Res , vol.785 , pp. 195-206
    • Hu, J.1    Akama, K.T.2    Krafft, G.A.3    Chromy, B.A.4    Van Eldik, L.J.5
  • 36
    • 0036445858 scopus 로고    scopus 로고
    • Increased p75 (NTR) expression in hippocampal neurons containing hyperphosphorylated tau in Alzheimer patients
    • Hu XY, Zhang HY, Qin S, Xu H, Swaab DF, Zhou JN. 2002. Increased p75 (NTR) expression in hippocampal neurons containing hyperphosphorylated tau in Alzheimer patients. Exp Neurol 178:104-111.
    • (2002) Exp Neurol , vol.178 , pp. 104-111
    • Hu, X.Y.1    Zhang, H.Y.2    Qin, S.3    Xu, H.4    Swaab, D.F.5    Zhou, J.N.6
  • 37
    • 12344323961 scopus 로고    scopus 로고
    • Tau phosphorylation in neuronal cell function and dysfunction
    • Johnson GV, Stoothoff WH. 2004. Tau phosphorylation in neuronal cell function and dysfunction. J Cell Sci 117:5721-5729.
    • (2004) J Cell Sci , vol.117 , pp. 5721-5729
    • Johnson, G.V.1    Stoothoff, W.H.2
  • 38
    • 0024204370 scopus 로고
    • Immunohistochemical localization of cells containing nerve growth factor receptors in the different regions of the adult rat forebrain
    • Kiss J, McGovern J, Patel AJ. 1988. Immunohistochemical localization of cells containing nerve growth factor receptors in the different regions of the adult rat forebrain. Neuroscience 27:731-748.
    • (1988) Neuroscience , vol.27 , pp. 731-748
    • Kiss, J.1    McGovern, J.2    Patel, A.J.3
  • 39
    • 0033971986 scopus 로고    scopus 로고
    • Nerve growth factor in glia and inflammatory cells of the injured rat spinal cord
    • Krenz NR, Weaver LC. 2000. Nerve growth factor in glia and inflammatory cells of the injured rat spinal cord. J Neurochem 74:730-739.
    • (2000) J Neurochem , vol.74 , pp. 730-739
    • Krenz, N.R.1    Weaver, L.C.2
  • 42
    • 0024365473 scopus 로고
    • Expression of NGF and NGF receptor mRNAs in the developing brain: Evidence for local delivery and action of NGF
    • Lu B, Buck CR, Dreyfus CF, Black IB. 1989. Expression of NGF and NGF receptor mRNAs in the developing brain: evidence for local delivery and action of NGF. Exp Neurol 104:191-199.
    • (1989) Exp Neurol , vol.104 , pp. 191-199
    • Lu, B.1    Buck, C.R.2    Dreyfus, C.F.3    Black, I.B.4
  • 43
    • 0034829801 scopus 로고    scopus 로고
    • The molecular bases of Alzheimer's disease and other neurodegenerative disorders
    • Maccioni RB, Muñoz JP, Barbeito L. 2001. The molecular bases of Alzheimer's disease and other neurodegenerative disorders. Arch Med Res 32:367-381.
    • (2001) Arch Med Res , vol.32 , pp. 367-381
    • Maccioni, R.B.1    Muñoz, J.P.2    Barbeito, L.3
  • 44
    • 0033034720 scopus 로고    scopus 로고
    • Neuronal life and death decisions: Functional antagonism between the Trk and p75 neurotrophin receptors
    • Majdan M, Miller F. 1999. Neuronal life and death decisions: functional antagonism between the Trk and p75 neurotrophin receptors. Int J Dev Neurosci 17:153-161.
    • (1999) Int J Dev Neurosci , vol.17 , pp. 153-161
    • Majdan, M.1    Miller, F.2
  • 45
    • 0020554780 scopus 로고
    • Fibrous astrocytes in Alzheimer's disease and senile dementia of Alzheimer's type
    • Mancardi GL, Liwnicz BH, Mandybur TI. 1983. Fibrous astrocytes in Alzheimer's disease and senile dementia of Alzheimer's type. Acta Neuropathol 61:76-80.
    • (1983) Acta Neuropathol , vol.61 , pp. 76-80
    • Mancardi, G.L.1    Liwnicz, B.H.2    Mandybur, T.I.3
  • 47
    • 0034875314 scopus 로고    scopus 로고
    • Neurotrophin signalling pathways regulating neuronal apoptosis
    • Miller FD, Kaplan DR. 2001. Neurotrophin signalling pathways regulating neuronal apoptosis. Cell Mol Life Sci 58:1045-1053.
    • (2001) Cell Mol Life Sci , vol.58 , pp. 1045-1053
    • Miller, F.D.1    Kaplan, D.R.2
  • 48
    • 0026571233 scopus 로고
    • Cortical neurons express nerve growth factor receptors in advanced age and Alzheimer disease
    • Mufson EJ, Kordower JH. 1992. Cortical neurons express nerve growth factor receptors in advanced age and Alzheimer disease. Proc Natl Acad Sci U S A 89:569-573.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 569-573
    • Mufson, E.J.1    Kordower, J.H.2
  • 49
    • 0031194454 scopus 로고    scopus 로고
    • Reduction in p140-TrkA receptor protein within the nucleus basalis and cortex in Alzheimer's disease
    • Mufson EJ, Lavine N, Jaffar S, Kordower JH, Quirion R, Saragovi HU. 1997. Reduction in p140-TrkA receptor protein within the nucleus basalis and cortex in Alzheimer's disease. Exp Neurol 146:91-103.
    • (1997) Exp Neurol , vol.146 , pp. 91-103
    • Mufson, E.J.1    Lavine, N.2    Jaffar, S.3    Kordower, J.H.4    Quirion, R.5    Saragovi, H.U.6
  • 53
  • 54
    • 2942536284 scopus 로고    scopus 로고
    • Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease
    • Peng S, Wuu J, Mufson EJ, Fahnestock M. 2004. Increased proNGF levels in subjects with mild cognitive impairment and mild Alzheimer disease. J Neuropathol Exp Neurol 63:641-649.
    • (2004) J Neuropathol Exp Neurol , vol.63 , pp. 641-649
    • Peng, S.1    Wuu, J.2    Mufson, E.J.3    Fahnestock, M.4
  • 55
    • 0028172346 scopus 로고
    • Beta-amyloid-induced changes in cultured astrocytes parallel reactive astrocytosis associated with senile plaques in Alzheimer's disease
    • Pike CJ, Cummings BJ, Monzavi R, Cotman CW. 1994. Beta-amyloid-induced changes in cultured astrocytes parallel reactive astrocytosis associated with senile plaques in Alzheimer's disease. Neuroscience 63:517-531.
    • (1994) Neuroscience , vol.63 , pp. 517-531
    • Pike, C.J.1    Cummings, B.J.2    Monzavi, R.3    Cotman, C.W.4
  • 56
    • 0030924506 scopus 로고    scopus 로고
    • Beta-amyloid neurotoxicity in vitro: Evidence of oxidative stress but not protection by antioxidants
    • Pike CJ, Ramezan-Arab N, Cotman CW. 1997. Beta-amyloid neurotoxicity in vitro: evidence of oxidative stress but not protection by antioxidants. J Neurochem 69:1601-1611.
    • (1997) J Neurochem , vol.69 , pp. 1601-1611
    • Pike, C.J.1    Ramezan-Arab, N.2    Cotman, C.W.3
  • 57
    • 0028670573 scopus 로고
    • Is p75NGFR involved in developmental neural cell death?
    • Rabizadeh S, Bredesen DE. 1994. Is p75NGFR involved in developmental neural cell death? Dev Neurosci 16:207-211.
    • (1994) Dev Neurosci , vol.16 , pp. 207-211
    • Rabizadeh, S.1    Bredesen, D.E.2
  • 58
    • 1342269756 scopus 로고    scopus 로고
    • Coupled reductions in brain oxidative phosphorylation and synaptic function can be quantified and staged in the course of Alzheimer's disease
    • Rappaport SI. 2003. Coupled reductions in brain oxidative phosphorylation and synaptic function can be quantified and staged in the course of Alzheimer's disease. Neurotox Res 5:385-398.
    • (2003) Neurotox Res , vol.5 , pp. 385-398
    • Rappaport, S.I.1
  • 59
    • 0033566919 scopus 로고    scopus 로고
    • p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure
    • Roux PP, Colicos MA, Barker PA, Kennedy TE. 1999. p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure. J. Neurosci 19:6887-6896.
    • (1999) J Neurosci , vol.19 , pp. 6887-6896
    • Roux, P.P.1    Colicos, M.A.2    Barker, P.A.3    Kennedy, T.E.4
  • 60
    • 4043058045 scopus 로고    scopus 로고
    • Astrocytic nitric oxide triggers tau hyperphosphorylation in hippocampal neurons
    • Sáez TE, Pehar M, Vargas M, Barbeito L, Maccioni RB. 2004. Astrocytic nitric oxide triggers tau hyperphosphorylation in hippocampal neurons. In Vivo 18:275-280.
    • (2004) In Vivo , vol.18 , pp. 275-280
    • Sáez, T.E.1    Pehar, M.2    Vargas, M.3    Barbeito, L.4    Maccioni, R.B.5
  • 61
    • 0002734426 scopus 로고
    • Neuronal and glial cells: Cell culture of the central nervous system
    • Turner AJ, Brachelard HS, editors. Washington, DC: IRL Press
    • Saneto RP, De Vellis J. 1987. Neuronal and glial cells: cell culture of the central nervous system. In: Turner AJ, Brachelard HS, editors. Neurochemistry: a practical approach. Washington, DC: IRL Press, p 27-63.
    • (1987) Neurochemistry: A Practical Approach , pp. 27-63
    • Saneto, R.P.1    De Vellis, J.2
  • 62
    • 0033768568 scopus 로고    scopus 로고
    • Alterations in trk A, trk B and trk C receptor immunoreactivities in parietal cortex and cerebellum in Alzheimer's disease
    • Savaskan E, Muller-Spahn F, Olivieri G, Bruttel S, Otten U, Rosenberg C, Hulette C, Hock C. 2000. Alterations in trk A, trk B and trk C receptor immunoreactivities in parietal cortex and cerebellum in Alzheimer's disease. Eur Neurol 44:172-180.
    • (2000) Eur Neurol , vol.44 , pp. 172-180
    • Savaskan, E.1    Muller-Spahn, F.2    Olivieri, G.3    Bruttel, S.4    Otten, U.5    Rosenberg, C.6    Hulette, C.7    Hock, C.8
  • 63
    • 0019805463 scopus 로고
    • Fibrous astrocytes in senile dementia of the Alzheimer type
    • Schechter R, Yen SH, Terry RD. 1981. Fibrous astrocytes in senile dementia of the Alzheimer type. J Neuropathol Exp Neurol 40:95-101.
    • (1981) J Neuropathol Exp Neurol , vol.40 , pp. 95-101
    • Schechter, R.1    Yen, S.H.2    Terry, R.D.3
  • 64
    • 0029022112 scopus 로고
    • Nerve growth factor in Alzheimer's disease: Increased levels throughout the brain coupled with declines in nucleus basalis
    • Scott SA, Mufson EJ, Weingartner JA, Skau KA, Crutcher KA. 1995. Nerve growth factor in Alzheimer's disease: increased levels throughout the brain coupled with declines in nucleus basalis. J Neurosci 15:6213-6221.
    • (1995) J Neurosci , vol.15 , pp. 6213-6221
    • Scott, S.A.1    Mufson, E.J.2    Weingartner, J.A.3    Skau, K.A.4    Crutcher, K.A.5
  • 66
    • 0028238769 scopus 로고
    • Functions of the neurotrophins during nervous system development: What the knockouts are teaching us
    • Snider WD. 1994. Functions of the neurotrophins during nervous system development: what the knockouts are teaching us. Cell 77:627-638.
    • (1994) Cell , vol.77 , pp. 627-638
    • Snider, W.D.1
  • 67
    • 0037072873 scopus 로고    scopus 로고
    • Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases
    • Troy CM, Friedman JE, Friedman WJ. 2002. Mechanisms of p75-mediated death of hippocampal neurons. Role of caspases. J Biol Chem 277:34295-34302.
    • (2002) J Biol Chem , vol.277 , pp. 34295-34302
    • Troy, C.M.1    Friedman, J.E.2    Friedman, W.J.3
  • 69
    • 0025513602 scopus 로고
    • Nerve growth factor infusion in the primate brain reduces lesion-induced cholinergic neuronal degeneration
    • Tuszynski MH, U HS, Amaral DG, Gage FH. 1990. Nerve growth factor infusion in the primate brain reduces lesion-induced cholinergic neuronal degeneration. J Neurosci 10:3604-3614.
    • (1990) J Neurosci , vol.10 , pp. 3604-3614
    • Tuszynski, M.H.1    U, H.S.2    Amaral, D.G.3    Gage, F.H.4
  • 70
    • 35748984061 scopus 로고    scopus 로고
    • Microglial and astrocytic reactions in Alzheimer's disease
    • De Vellis JS, editor. Totowa, NJ: Humana Press
    • Walker DG, Beach TG. 2002. Microglial and astrocytic reactions in Alzheimer's disease. In: De Vellis JS, editor. Neuroglia in the aging brain. Totowa, NJ: Humana Press, p 339-363.
    • (2002) Neuroglia in the Aging Brain , pp. 339-363
    • Walker, D.G.1    Beach, T.G.2
  • 71
    • 0024990330 scopus 로고
    • Neurotrophic and neurotoxic effects of amyloid beta protein: Reversal by tachykinin neuropeptides
    • Yankner BA, Duffy LK, Kirschner DA. 1990. Neurotrophic and neurotoxic effects of amyloid beta protein: reversal by tachykinin neuropeptides. Science 250:279-282.
    • (1990) Science , vol.250 , pp. 279-282
    • Yankner, B.A.1    Duffy, L.K.2    Kirschner, D.A.3
  • 72
    • 0025610499 scopus 로고
    • Fibroblast growth factors stimulate nerve growth factor synthesis and secretion by astrocytes
    • Yoshida K, Gage FH. 1991. Fibroblast growth factors stimulate nerve growth factor synthesis and secretion by astrocytes. Brain Res 538:118-126.
    • (1991) Brain Res , vol.538 , pp. 118-126
    • Yoshida, K.1    Gage, F.H.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.