A missense mutation (L166P) in DJ-1, linked to familial Parkinson's disease, confers reduced protein stability and impairs homo-oligomerization

Journal of Neurochemistry

Volumn 87, Issue 6, 2003, Pages 1558-1567

  Moore, Darren J ^a   Zhang, Li ^a   Dawson, Ted M ^a   Dawson, Valina L ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

DJ 1; Homo dimerization; L166P; M261; PARK7 locus; Parkinson's disease

Indexed keywords

MESSENGER RNA; PROTEASOME;

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CRYSTAL STRUCTURE; DJ 1 GENE; EUROPE; EXON; FAMILIAL DISEASE; GENE; GENE DELETION; GENE LOCUS; GENE MUTATION; HUMAN; HUMAN CELL; IN VIVO STUDY; MISSENSE MUTATION; OLIGOMERIZATION; PARKINSON DISEASE; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN STABILITY;

HOMO;

EID: 0346434141     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2003.02265.x     Document Type: Article

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