Protective effect of lipoic acid against oxidative stress is mediated by Keap1/Nrf2-dependent heme oxygenase-1 induction in the RGC-5 cellline

Brain Research

Volumn 1499, Issue , 2013, Pages 145-157

  Koriyama, Yoshiki ^a   Nakayama, Yuya ^a   Matsugo, Seiichi ^a   Kato, Satoru ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

Akt; HO 1; Keap1; Lipoic acid; Oxidative stress; Retinal ganglion cell

Indexed keywords

4 HYDROXYNONENAL; HEME OXYGENASE 1; HYDROGEN PEROXIDE; KELCH LIKE ECH ASSOCIATED PROTEIN 1; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; THIOCTIC ACID; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CELL LINE; ENZYME ACTIVITY; ENZYME INDUCTION; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEUROPROTECTION; NONHUMAN; OPTIC NERVE INJURY; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA NERVE CELL; SIGNAL TRANSDUCTION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BLOTTING, WESTERN; CELL LINE; CYTOSKELETAL PROTEINS; HEME OXYGENASE-1; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MICE; NEUROPROTECTIVE AGENTS; OXIDATIVE STRESS; RETINAL GANGLION CELLS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; THIOCTIC ACID;

EID: 84873720037     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.12.041     Document Type: Article

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