-
1
-
-
45249108473
-
Structure–function implications in Alzheimer’s disease: effect of Abeta oligomers at central synapses
-
W.Cerpa, M.C.Dinamarca, N.C.Inestrosa. Structure–function implications in Alzheimer’s disease: effect of Abeta oligomers at central synapses. Curr Alzheimer Res 2008;5:233–243.
-
(2008)
Curr Alzheimer Res
, vol.5
, pp. 233-243
-
-
Cerpa, W.1
Dinamarca, M.C.2
Inestrosa, N.C.3
-
2
-
-
84861202049
-
Rutin inhibits β-amyloid aggregation and cytotoxicity, attenuates oxidative stress, and decreases the production of nitric oxide and proinflammatory cytokines
-
S.W.Wang, Y.J.Wang, Y.J.Su, W.W.Zhou, S.G.Yang, R.Zhang,. Rutin inhibits β-amyloid aggregation and cytotoxicity, attenuates oxidative stress, and decreases the production of nitric oxide and proinflammatory cytokines. Neurotoxicology 2012;33:482–490.
-
(2012)
Neurotoxicology
, vol.33
, pp. 482-490
-
-
Wang, S.W.1
Wang, Y.J.2
Su, Y.J.3
Zhou, W.W.4
Yang, S.G.5
Zhang, R.6
-
3
-
-
0026353502
-
Amnestic effects in mice of four synthetic peptides homologous to amyloid beta protein from patients with Alzheimer disease
-
J.F.Flood, J.E.Morley, E.Roberts. Amnestic effects in mice of four synthetic peptides homologous to amyloid beta protein from patients with Alzheimer disease. Proc Natl Acad Sci USA 1991;88:3363–3366.
-
(1991)
Proc Natl Acad Sci USA
, vol.88
, pp. 3363-3366
-
-
Flood, J.F.1
Morley, J.E.2
Roberts, E.3
-
4
-
-
0035943436
-
Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils
-
J.Götz, F.Chen, J.Van Dorpe, R.M.Nitsch. Formation of neurofibrillary tangles in P301l tau transgenic mice induced by Abeta 42 fibrils. Science 2001;293:1491–1495.
-
(2001)
Science
, vol.293
, pp. 1491-1495
-
-
Götz, J.1
Chen, F.2
Van Dorpe, J.3
Nitsch, R.M.4
-
5
-
-
84859009663
-
Novel S-acyl glutathione derivatives prevent amyloid oxidative stress and cholinergic dysfunction in Alzheimer disease models
-
M.Zampagni, D.Wright, R.Cascella, G.D’Adamio, F.Casamenti, E.Evangelisti,. Novel S-acyl glutathione derivatives prevent amyloid oxidative stress and cholinergic dysfunction in Alzheimer disease models. Free Radic Biol Med 2012;52:1362–1371.
-
(2012)
Free Radic Biol Med
, vol.52
, pp. 1362-1371
-
-
Zampagni, M.1
Wright, D.2
Cascella, R.3
D’Adamio, G.4
Casamenti, F.5
Evangelisti, E.6
-
6
-
-
0034923434
-
Oxidative damage is the earliest event in Alzheimer disease
-
A.Nunomura, G.Perry, G.Aliev, K.Hirai, A.Takeda, E.K.Balraj,. Oxidative damage is the earliest event in Alzheimer disease. J Neuropathol Exp Neurol 2001;60:759–767.
-
(2001)
J Neuropathol Exp Neurol
, vol.60
, pp. 759-767
-
-
Nunomura, A.1
Perry, G.2
Aliev, G.3
Hirai, K.4
Takeda, A.5
Balraj, E.K.6
-
7
-
-
71749121998
-
Mitochondrial dysfunction is a trigger of Alzheimer’s disease pathophysiology
-
P.I.Moreira, C.Carvalho, X.W.Zhu, M.A.Smith, G.Perry. Mitochondrial dysfunction is a trigger of Alzheimer’s disease pathophysiology. Biochim Biophys Acta 2010;1802:2–10.
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 2-10
-
-
Moreira, P.I.1
Carvalho, C.2
Zhu, X.W.3
Smith, M.A.4
Perry, G.5
-
8
-
-
69949107465
-
The unsolved relationship of brain aging and late-onset Alzheimer disease
-
A.Kern, C.Behl The unsolved relationship of brain aging and late-onset Alzheimer disease. Biochim Biophys Acta 2009;1790:1124–1132.
-
(2009)
Biochim Biophys Acta
, vol.1790
, pp. 1124-1132
-
-
Kern, A.1
Behl, C.2
-
9
-
-
27544484846
-
Are mitochondria critical in the pathogenesis of Alzheimer’s disease?
-
P.H.Reddy, M.F.Beal Are mitochondria critical in the pathogenesis of Alzheimer’s disease? Brain Res Brain Res Rev 2005;49:618–632.
-
(2005)
Brain Res Brain Res Rev
, vol.49
, pp. 618-632
-
-
Reddy, P.H.1
Beal, M.F.2
-
10
-
-
33745727582
-
Oxidative stress in Alzheimer’s disease
-
V.Chauhan, A.Chauhan. Oxidative stress in Alzheimer’s disease. Pathophysiology 2006;13:195–208.
-
(2006)
Pathophysiology
, vol.13
, pp. 195-208
-
-
Chauhan, V.1
Chauhan, A.2
-
11
-
-
43849096294
-
Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease
-
R.Resende, P.I.Moreira, T.Proenca, A.Deshpande, J.Busciglio, C.Pereira,. Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease. Free Radic Biol Med 2008;44:2051–2057.
-
(2008)
Free Radic Biol Med
, vol.44
, pp. 2051-2057
-
-
Resende, R.1
Moreira, P.I.2
Proenca, T.3
Deshpande, A.4
Busciglio, J.5
Pereira, C.6
-
12
-
-
0032510692
-
Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism
-
K.T.Akama, C.Albanese, R.G.Pestell, L.J.Van Eldik Amyloid beta-peptide stimulates nitric oxide production in astrocytes through an NFkappaB-dependent mechanism. Proc Natl Acad Sci USA 1998;95:5795–5800.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 5795-5800
-
-
Akama, K.T.1
Albanese, C.2
Pestell, R.G.3
Van Eldik, L.J.4
-
13
-
-
20544432465
-
Role of fibrillar Abeta25–35 in the inflammation induced rat model with respect to oxidative vulnerability
-
J.G.Masilamoni, E.P.Jesudason, K.S.Jesudoss, J.Murali, S.F.Paul, R.Jayakumar. Role of fibrillar Abeta25–35 in the inflammation induced rat model with respect to oxidative vulnerability. Free Radic Res 2005;39:603–612.
-
(2005)
Free Radic Res
, vol.39
, pp. 603-612
-
-
Masilamoni, J.G.1
Jesudason, E.P.2
Jesudoss, K.S.3
Murali, J.4
Paul, S.F.5
Jayakumar, R.6
-
14
-
-
34648859471
-
Oxidative damage in mild cognitive impairment and early Alzheimer’s disease
-
M.A.Lovell, W.R.Markesbery. Oxidative damage in mild cognitive impairment and early Alzheimer’s disease. J Neurosci Res 2007;85:3036–3040.
-
(2007)
J Neurosci Res
, vol.85
, pp. 3036-3040
-
-
Lovell, M.A.1
Markesbery, W.R.2
-
15
-
-
18744369020
-
Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington’s disease by using an automated filter retardation assay
-
V.Heiser, S.Engemann, W.Brocker, I.Dunkel, A.Boeddrich, S.Waelter,. Identification of benzothiazoles as potential polyglutamine aggregation inhibitors of Huntington’s disease by using an automated filter retardation assay. Proc Natl Acad Sci USA 2002;99:16400–16406.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 16400-16406
-
-
Heiser, V.1
Engemann, S.2
Brocker, W.3
Dunkel, I.4
Boeddrich, A.5
Waelter, S.6
-
16
-
-
4043122453
-
Riluzole slows the progression of neuromuscular dysfunction in the wobbler mouse motor neuron disease
-
T.Ishiyama, R.Okada, H.Nishibe, H.Mitsumoto, C.Nakayama Riluzole slows the progression of neuromuscular dysfunction in the wobbler mouse motor neuron disease. Brain Res 2004;1019:226–236.
-
(2004)
Brain Res
, vol.1019
, pp. 226-236
-
-
Ishiyama, T.1
Okada, R.2
Nishibe, H.3
Mitsumoto, H.4
Nakayama, C.5
-
17
-
-
33645999638
-
Anti-tumor drug candidate 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole induces single strand breaks and DNA–protein cross-links in sensitive MCF-7 breast cancer cells
-
E.Brantley, S.Antony, G.Kohlhagen, L.H.Meng, K.Agama, S.F.Stinson,. Anti-tumor drug candidate 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole induces single strand breaks and DNA–protein cross-links in sensitive MCF-7 breast cancer cells. Cancer Chemother Pharmacol 2006;58:62–72.
-
(2006)
Cancer Chemother Pharmacol
, vol.58
, pp. 62-72
-
-
Brantley, E.1
Antony, S.2
Kohlhagen, G.3
Meng, L.H.4
Agama, K.5
Stinson, S.F.6
-
18
-
-
30444437324
-
Antitumor benzothiazoles. 26.1 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines
-
C.G.Mortimer, G.Wells, J.P.Crochard, E.L.Stone, T.D.Bradshaw, M.F.Stevens,. Antitumor benzothiazoles. 26.1 2-(3,4-dimethoxyphenyl)-5-fluorobenzothiazole (GW 610, NSC 721648), a simple fluorinated 2-arylbenzothiazole, shows potent and selective inhibitory activity against lung, colon, and breast cancer cell lines. J Med Chem 2006;49:179–185.
-
(2006)
J Med Chem
, vol.49
, pp. 179-185
-
-
Mortimer, C.G.1
Wells, G.2
Crochard, J.P.3
Stone, E.L.4
Bradshaw, T.D.5
Stevens, M.F.6
-
19
-
-
33745142870
-
Iminotetrahydro-benzothiazole derivatives as p53 inhibitors: discovery of a highly potent in vivo inhibitor and its action mechanism
-
N.Pietrancosta, A.Moumen, R.Dono, P.Lingor, V.Planchamp, F.Lamballe,. Iminotetrahydro-benzothiazole derivatives as p53 inhibitors: discovery of a highly potent in vivo inhibitor and its action mechanism. J Med Chem 2006;49:3645–3652.
-
(2006)
J Med Chem
, vol.49
, pp. 3645-3652
-
-
Pietrancosta, N.1
Moumen, A.2
Dono, R.3
Lingor, P.4
Planchamp, V.5
Lamballe, F.6
-
20
-
-
49849097899
-
KNS-760704 [(6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine dihydrochloride monohydrate] for the treatment of amyotrophic lateral sclerosis
-
V.K.Gribkoff, M.E.Bozik. KNS-760704 [(6R)-4,5,6,7-tetrahydro-N6-propyl-2,6-benzothiazole-diamine dihydrochloride monohydrate] for the treatment of amyotrophic lateral sclerosis. CNS Neurosci Ther 2008;14:215–226.
-
(2008)
CNS Neurosci Ther
, vol.14
, pp. 215-226
-
-
Gribkoff, V.K.1
Bozik, M.E.2
-
21
-
-
79951821156
-
2-Aminothiazoles as therapeutic leads for prion diseases
-
A.Gallardo-Godoy, J.Gever, K.L.Fife, B.M.Silber, S.B.Prusiner, A.R.Renslo 2-Aminothiazoles as therapeutic leads for prion diseases. J Med Chem 2011;54:1010–1021.
-
(2011)
J Med Chem
, vol.54
, pp. 1010-1021
-
-
Gallardo-Godoy, A.1
Gever, J.2
Fife, K.L.3
Silber, B.M.4
Prusiner, S.B.5
Renslo, A.R.6
-
22
-
-
84877058929
-
2-Aminothiazoles with improved pharmacotherapeutic properties for treatment of prion disease
-
Z.Li, B.M.Silber, S.Rao, J.R.Gever, C.Bryant, A.Gallardo-Godoy,. 2-Aminothiazoles with improved pharmacotherapeutic properties for treatment of prion disease. ChemMedChem 2013;8:847–857.
-
(2013)
ChemMedChem
, vol.8
, pp. 847-857
-
-
Li, Z.1
Silber, B.M.2
Rao, S.3
Gever, J.R.4
Bryant, C.5
Gallardo-Godoy, A.6
-
23
-
-
77249093092
-
Synthesis and biological evaluation of amidine, guanidine, and thiourea derivatives of 2-amino(6-trifluoromethoxy)benzothiazole as neuroprotective agents potentially useful in brain diseases
-
M.Anzini, A.Chelini, A.Mancini, A.Cappelli, M.Frosini, L.Ricci,. Synthesis and biological evaluation of amidine, guanidine, and thiourea derivatives of 2-amino(6-trifluoromethoxy)benzothiazole as neuroprotective agents potentially useful in brain diseases. J Med Chem 2010;53:734–744.
-
(2010)
J Med Chem
, vol.53
, pp. 734-744
-
-
Anzini, M.1
Chelini, A.2
Mancini, A.3
Cappelli, A.4
Frosini, M.5
Ricci, L.6
-
24
-
-
84903738660
-
Anti-inflammatory mechanisms of N-adamantyl-4-methylthiazol-2-amine in lipopolysaccharide-stimulated BV-2 microglial cells
-
E.A.Kim, A.R.Han, J.Choi, J.Y.Ahn, S.Y.Choi, S.W.Cho Anti-inflammatory mechanisms of N-adamantyl-4-methylthiazol-2-amine in lipopolysaccharide-stimulated BV-2 microglial cells. Int Immunopharmacol 2014;22:73–83.
-
(2014)
Int Immunopharmacol
, vol.22
, pp. 73-83
-
-
Kim, E.A.1
Han, A.R.2
Choi, J.3
Ahn, J.Y.4
Choi, S.Y.5
Cho, S.W.6
-
25
-
-
84900352195
-
Effects of N-adamantyl-4-methylthiazol-2-amine on hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic rats
-
S.J.Yang, W.J.Lee, E.A.Kim, K.D.Nam, H.G.Hahn, S.Y.Choi,. Effects of N-adamantyl-4-methylthiazol-2-amine on hyperglycemia, hyperlipidemia and oxidative stress in streptozotocin-induced diabetic rats. Eur J Pharmacol 2014;736:26–34.
-
(2014)
Eur J Pharmacol
, vol.736
, pp. 26-34
-
-
Yang, S.J.1
Lee, W.J.2
Kim, E.A.3
Nam, K.D.4
Hahn, H.G.5
Choi, S.Y.6
-
26
-
-
0037444535
-
The binding of 2-(4′-methylaminophenyl)benzothiazole to postmortem brain homogenates is dominated by the amyloid component
-
W.E.Klunk, Y.Wang, G.F.Huang, M.L.Debnath, D.P.Holt, L.Shao,. The binding of 2-(4′-methylaminophenyl)benzothiazole to postmortem brain homogenates is dominated by the amyloid component. J Neurosci 2003;23:2086–2092.
-
(2003)
J Neurosci
, vol.23
, pp. 2086-2092
-
-
Klunk, W.E.1
Wang, Y.2
Huang, G.F.3
Debnath, M.L.4
Holt, D.P.5
Shao, L.6
-
27
-
-
48149107920
-
Thioflavin derivatives as markers for amyloid-beta fibrils: insights into structural features important for high-affinity binding
-
R.Leuma Yona, S.Mazères, P.Faller, E.Gras Thioflavin derivatives as markers for amyloid-beta fibrils: insights into structural features important for high-affinity binding. ChemMedChem 2008;3:63–66.
-
(2008)
ChemMedChem
, vol.3
, pp. 63-66
-
-
Leuma Yona, R.1
Mazères, S.2
Faller, P.3
Gras, E.4
-
28
-
-
34548299422
-
Protective effect of benzothiazole derivative KHG21834 on amyloid beta-induced neurotoxicity in PC12 cells and cortical and mesencephalic neurons
-
M.M.Choi, E.A.Kim, H.G.Hahn, K.D.Nam, S.J.Yang, S.Y.Choi,. Protective effect of benzothiazole derivative KHG21834 on amyloid beta-induced neurotoxicity in PC12 cells and cortical and mesencephalic neurons. Toxicology 2007;239:156–166.
-
(2007)
Toxicology
, vol.239
, pp. 156-166
-
-
Choi, M.M.1
Kim, E.A.2
Hahn, H.G.3
Nam, K.D.4
Yang, S.J.5
Choi, S.Y.6
-
29
-
-
40849130718
-
Panaxydol and panaxynol protect cultured cortical neurons against Abeta25–35-induced toxicity
-
B.M.Nie, X.Y.Jiang, J.X.Cai, S.L.Fu, L.M.Yang, L.Lin,. Panaxydol and panaxynol protect cultured cortical neurons against Abeta25–35-induced toxicity. Neuropharmacology 2008;54:845–853.
-
(2008)
Neuropharmacology
, vol.54
, pp. 845-853
-
-
Nie, B.M.1
Jiang, X.Y.2
Cai, J.X.3
Fu, S.L.4
Yang, L.M.5
Lin, L.6
-
30
-
-
7444227078
-
Melqatonin reduces amyloid β-induced apoptosis in pheochromocytoma (PC12) cells
-
Z.Feng, J.T.Zhang Melqatonin reduces amyloid β-induced apoptosis in pheochromocytoma (PC12) cells. J Pineal Res 2004;37:257–266.
-
(2004)
J Pineal Res
, vol.37
, pp. 257-266
-
-
Feng, Z.1
Zhang, J.T.2
-
31
-
-
84881303781
-
Anti-oxidative and anti-inflammatory effects of 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride on glutamate-induced neurotoxicity in rat brain
-
E.A.Kim, J.Choi, A.R.Han, S.Y.Choi, H.G.Hahn, S.W.Cho Anti-oxidative and anti-inflammatory effects of 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride on glutamate-induced neurotoxicity in rat brain. Neurotoxicology 2013;38:106–114.
-
(2013)
Neurotoxicology
, vol.38
, pp. 106-114
-
-
Kim, E.A.1
Choi, J.2
Han, A.R.3
Choi, S.Y.4
Hahn, H.G.5
Cho, S.W.6
-
32
-
-
84908869204
-
PEP-1-HO-1 prevents MPTP-induced degeneration of dopaminergic neurons in a Parkinson’s disease mouse model
-
J.K.Youn, D.W.Kim, S.T.Kim, S.Y.Park, E.J.Yeo, Y.J.Choi,. PEP-1-HO-1 prevents MPTP-induced degeneration of dopaminergic neurons in a Parkinson’s disease mouse model. BMB Rep 2014;47:569–574.
-
(2014)
BMB Rep
, vol.47
, pp. 569-574
-
-
Youn, J.K.1
Kim, D.W.2
Kim, S.T.3
Park, S.Y.4
Yeo, E.J.5
Choi, Y.J.6
-
33
-
-
84936164108
-
Anticancer activity of CopA3 dimer peptide in human gastric cancer cells
-
J.H.Lee, I.W.Kim, S.H.Kim, E.Y.Yun, S.H.Nam, M.Y.Ahn,. Anticancer activity of CopA3 dimer peptide in human gastric cancer cells. BMB Rep 2015;48:324–329.
-
(2015)
BMB Rep
, vol.48
, pp. 324-329
-
-
Lee, J.H.1
Kim, I.W.2
Kim, S.H.3
Yun, E.Y.4
Nam, S.H.5
Ahn, M.Y.6
-
34
-
-
84946229565
-
Effect of respiratory syncytial virus on the growth of hepatocellular carcinoma cell-lines
-
S.H.Choi, B.K.Park, K.W.Lee, J.Chang, Y.Lee, H.J.Kwon Effect of respiratory syncytial virus on the growth of hepatocellular carcinoma cell-lines. BMB Rep 2015;48:565–570.
-
(2015)
BMB Rep
, vol.48
, pp. 565-570
-
-
Choi, S.H.1
Park, B.K.2
Lee, K.W.3
Chang, J.4
Lee, Y.5
Kwon, H.J.6
-
35
-
-
84930915358
-
One-step isolation of sappanol and brazilin from Caesalpinia sappan and their effects on oxidative stress-induced retinal death
-
G.M.Uddin, C.Y.Kim, D.Chung, K.A.Kim, S.H.Jung One-step isolation of sappanol and brazilin from Caesalpinia sappan and their effects on oxidative stress-induced retinal death. BMB Rep 2015;48:289–294.
-
(2015)
BMB Rep
, vol.48
, pp. 289-294
-
-
Uddin, G.M.1
Kim, C.Y.2
Chung, D.3
Kim, K.A.4
Jung, S.H.5
-
36
-
-
84903555889
-
Salicortin suppresses lipopolysaccharide-stimulated inflammatory responses via blockade of NF-κB and JNK activation in RAW 264.7 macrophages
-
D.J.Kwon, Y.S.Bae, S.M.Ju, G.S.Youn, S.Y.Choi, J.Park Salicortin suppresses lipopolysaccharide-stimulated inflammatory responses via blockade of NF-κB and JNK activation in RAW 264.7 macrophages. BMB Rep 2014;47:318–323.
-
(2014)
BMB Rep
, vol.47
, pp. 318-323
-
-
Kwon, D.J.1
Bae, Y.S.2
Ju, S.M.3
Youn, G.S.4
Choi, S.Y.5
Park, J.6
-
37
-
-
84928265883
-
Celastrol ameliorates cytokine toxicity and pro-inflammatory immune responses by suppressing NF-κB activation in RINm5F beta cells
-
S.M.Ju, G.S.Youn, Y.S.Cho, S.Y.Choi, J.Park Celastrol ameliorates cytokine toxicity and pro-inflammatory immune responses by suppressing NF-κB activation in RINm5F beta cells. BMB Rep 2015;48:172–177.
-
(2015)
BMB Rep
, vol.48
, pp. 172-177
-
-
Ju, S.M.1
Youn, G.S.2
Cho, Y.S.3
Choi, S.Y.4
Park, J.5
-
38
-
-
0000274424
-
Glutathione reductase from bakers’ yeast and beef liver
-
E.Racker. Glutathione reductase from bakers’ yeast and beef liver. J Biol Chem 1995;217:855–865.
-
(1995)
J Biol Chem
, vol.217
, pp. 855-865
-
-
Racker, E.1
-
39
-
-
77955550149
-
Comparable attenuation of Abeta(25–35)-induced neurotoxicity by quercitrin and 17beta-estradiol in cultured rat hippocampal neurons
-
S.Rattanajarasroj, S.Unchern Comparable attenuation of Abeta(25–35)-induced neurotoxicity by quercitrin and 17beta-estradiol in cultured rat hippocampal neurons. Neurochem Res 2010;35:1196–1205.
-
(2010)
Neurochem Res
, vol.35
, pp. 1196-1205
-
-
Rattanajarasroj, S.1
Unchern, S.2
-
40
-
-
0028239163
-
Oxidative damage to proteins: spectrophotometric method for carbonyl assay
-
A.Z.Reznick, L.Packer Oxidative damage to proteins: spectrophotometric method for carbonyl assay. Meth Enzymol 1994;233:357–363.
-
(1994)
Meth Enzymol
, vol.233
, pp. 357-363
-
-
Reznick, A.Z.1
Packer, L.2
-
41
-
-
13644265462
-
Ferulic acid ethyl ester protects neurons against amyloid beta-peptide(1–42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity
-
R.Sultana, A.Ravagna, H.Mohmmad-Abdul, V.Calabrese, D.A.Butterfield Ferulic acid ethyl ester protects neurons against amyloid beta-peptide(1–42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity. J Neurochem 2005;92:749–758.
-
(2005)
J Neurochem
, vol.92
, pp. 749-758
-
-
Sultana, R.1
Ravagna, A.2
Mohmmad-Abdul, H.3
Calabrese, V.4
Butterfield, D.A.5
-
42
-
-
0017184389
-
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
-
M.M.Bradford. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976;72:248–254.
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
44
-
-
0036845314
-
Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species
-
L.Qin, Y.Liu, C.Cooper, B.Liu, B.Wilson, J.S.Hong. Microglia enhance beta-amyloid peptide-induced toxicity in cortical and mesencephalic neurons by producing reactive oxygen species. J Neurochem 2002;83:973–983.
-
(2002)
J Neurochem
, vol.83
, pp. 973-983
-
-
Qin, L.1
Liu, Y.2
Cooper, C.3
Liu, B.4
Wilson, B.5
Hong, J.S.6
-
45
-
-
1542283611
-
Neuroinflammatory perspectives on the two faces of Alzheimer’s disease
-
P.Eikelenboom, W.A.Gool Neuroinflammatory perspectives on the two faces of Alzheimer’s disease. J Neural Transm (Vienna) 2004;111:281–294.
-
(2004)
J Neural Transm (Vienna)
, vol.111
, pp. 281-294
-
-
Eikelenboom, P.1
Gool, W.A.2
-
46
-
-
84890048084
-
Nicotinamide treatment reduces the levels of oxidative stress, apoptosis, and PARP-1 activity in Aβ(1–42)-induced rat model of Alzheimer’s disease
-
E.Turunc Bayrakdar, Y.Uyanikgil, L.Kanit, E.Koylu, A.Yalcin Nicotinamide treatment reduces the levels of oxidative stress, apoptosis, and PARP-1 activity in Aβ(1–42)-induced rat model of Alzheimer’s disease. Free Radic Res 2014;48:146–158.
-
(2014)
Free Radic Res
, vol.48
, pp. 146-158
-
-
Turunc Bayrakdar, E.1
Uyanikgil, Y.2
Kanit, L.3
Koylu, E.4
Yalcin, A.5
-
47
-
-
0029081625
-
Riluzole prevents MPTP-induced parkinsonism in the rhesus monkey: a pilot study
-
A.Benazzouz, T.Boraud, P.Dubedat, A.Boireau, J.M.Stutzmann, C.Gross Riluzole prevents MPTP-induced parkinsonism in the rhesus monkey: a pilot study. Eur J Pharmacol 1995;284:299–307.
-
(1995)
Eur J Pharmacol
, vol.284
, pp. 299-307
-
-
Benazzouz, A.1
Boraud, T.2
Dubedat, P.3
Boireau, A.4
Stutzmann, J.M.5
Gross, C.6
-
48
-
-
66749130196
-
Novel orally bioavailable gamma-secretase inhibitors with excellent in vivo activity
-
L.E.Keown, I.Collins, L.C.Cooper, T.Harrison, A.Madin, J.Mistry,. Novel orally bioavailable gamma-secretase inhibitors with excellent in vivo activity. J Med Chem 2009;52:3441–3444.
-
(2009)
J Med Chem
, vol.52
, pp. 3441-3444
-
-
Keown, L.E.1
Collins, I.2
Cooper, L.C.3
Harrison, T.4
Madin, A.5
Mistry, J.6
-
49
-
-
33846032313
-
Radioligand development for PET imaging of beta-amyloid (Abeta)–current status
-
L.Cai, R.B.Innis, V.W.Pike Radioligand development for PET imaging of beta-amyloid (Abeta)–current status. Curr Med Chem 2007;14:19–52.
-
(2007)
Curr Med Chem
, vol.14
, pp. 19-52
-
-
Cai, L.1
Innis, R.B.2
Pike, V.W.3
-
50
-
-
77952320068
-
Molecular mechanism of thioflavin-T binding to amyloid fibrils
-
M.Biancalana, S.Koide Molecular mechanism of thioflavin-T binding to amyloid fibrils. Biochim Biophys Acta 2010;1804:1405–1412.
-
(2010)
Biochim Biophys Acta
, vol.1804
, pp. 1405-1412
-
-
Biancalana, M.1
Koide, S.2
-
51
-
-
84868542498
-
Liberation of copper from amyloid plaques: making a risk factor useful for Alzheimer’s disease treatment
-
J.Geng, M.Li, L.Wu, J.Ren, X.Qu. Liberation of copper from amyloid plaques: making a risk factor useful for Alzheimer’s disease treatment. J Med Chem 2012;55:9146–9155.
-
(2012)
J Med Chem
, vol.55
, pp. 9146-9155
-
-
Geng, J.1
Li, M.2
Wu, L.3
Ren, J.4
Qu, X.5
-
52
-
-
84868101106
-
O-linked β-N-acetylglucosaminidase inhibitor attenuates β-amyloid plaque and rescues memory impairment
-
C.Kim, D.W.Nam, S.Y.Park, H.Song, H.S.Hong, J.H.Boo,. O-linked β-N-acetylglucosaminidase inhibitor attenuates β-amyloid plaque and rescues memory impairment. Neurobiol Aging 2013;34:275–285.
-
(2013)
Neurobiol Aging
, vol.34
, pp. 275-285
-
-
Kim, C.1
Nam, D.W.2
Park, S.Y.3
Song, H.4
Hong, H.S.5
Boo, J.H.6
-
53
-
-
84884573236
-
PARP-1 modulates amyloid beta peptide-induced neuronal damage
-
S.Martire, A.Fuso, D.Rotili, I.Tempera, C.Giordano, I.De Zottis,. PARP-1 modulates amyloid beta peptide-induced neuronal damage. PLoS One 2013;8:e72169.
-
(2013)
PLoS One
, vol.8
, pp. e72169
-
-
Martire, S.1
Fuso, A.2
Rotili, D.3
Tempera, I.4
Giordano, C.5
De Zottis, I.6
-
54
-
-
84870798936
-
Protective effect of puerarin against beta-amyloid-induced oxidative stress in neuronal cultures from rat hippocampus: involvement of the GSK-3β/Nrf2 signaling pathway
-
Y.Zou, B.Hong, L.Fan, L.Zhou, Y.Liu, Q.Wu, X.Zhang, M.Dong Protective effect of puerarin against beta-amyloid-induced oxidative stress in neuronal cultures from rat hippocampus: involvement of the GSK-3β/Nrf2 signaling pathway. Free Radic Res 2013;47:55–63.
-
(2013)
Free Radic Res
, vol.47
, pp. 55-63
-
-
Zou, Y.1
Hong, B.2
Fan, L.3
Zhou, L.4
Liu, Y.5
Wu, Q.6
Zhang, X.7
Dong, M.8
-
55
-
-
0042672741
-
Caspase-independent cell death by low concentrations of nitric oxide in PC12 cells: involvement of cytochrome C oxidase inhibition and the production of reactive oxygen species in mitochondria
-
K.Yuyama, H.Yamamoto, I.Nishizaki, T.Kato, I.Sora, T.Yamamoto Caspase-independent cell death by low concentrations of nitric oxide in PC12 cells: involvement of cytochrome C oxidase inhibition and the production of reactive oxygen species in mitochondria. J Neurosci Res 2003;3:351–363.
-
(2003)
J Neurosci Res
, vol.3
, pp. 351-363
-
-
Yuyama, K.1
Yamamoto, H.2
Nishizaki, I.3
Kato, T.4
Sora, I.5
Yamamoto, T.6
-
56
-
-
34848899898
-
Amyloid-beta-induced mitochondrial dysfunction
-
J.X.Chen, S.D.Yan Amyloid-beta-induced mitochondrial dysfunction. J Alzheimers Dis 2007;12:177–184.
-
(2007)
J Alzheimers Dis
, vol.12
, pp. 177-184
-
-
Chen, J.X.1
Yan, S.D.2
-
57
-
-
79751480420
-
Oxidative balance in Alzheimer’s disease: relationship to APOE, Braak tangle stage, and the concentrations of soluble and insoluble amyloid-β
-
H.Tayler, T.Fraser, J.S.Miners, P.G.Kehoe, S.Love Oxidative balance in Alzheimer’s disease: relationship to APOE, Braak tangle stage, and the concentrations of soluble and insoluble amyloid-β. J Alzheimers Dis 2010;22:1363–1373.
-
(2010)
J Alzheimers Dis
, vol.22
, pp. 1363-1373
-
-
Tayler, H.1
Fraser, T.2
Miners, J.S.3
Kehoe, P.G.4
Love, S.5
-
58
-
-
78650685650
-
β-Amyloid peptide increases levels of iron content and oxidative stress in human cell and Caenorhabditis elegans models of Alzheimer disease
-
L.Wan, G.Nie, J.Zhang, Y.Luo, P.Zhang, Z.Zhang,. β-Amyloid peptide increases levels of iron content and oxidative stress in human cell and Caenorhabditis elegans models of Alzheimer disease. Free Radic Biol Med 2011;50:122–129.
-
(2011)
Free Radic Biol Med
, vol.50
, pp. 122-129
-
-
Wan, L.1
Nie, G.2
Zhang, J.3
Luo, Y.4
Zhang, P.5
Zhang, Z.6
-
59
-
-
0346728670
-
Neurotoxicity, oxidative stress and cerebrovascular disorders
-
G.A.Qureshi, S.Baig, M.Sarwar, S.H.Parvez Neurotoxicity, oxidative stress and cerebrovascular disorders. Neurotoxicology 2004;25;121–138.
-
(2004)
Neurotoxicology
, vol.25
, pp. 121-138
-
-
Qureshi, G.A.1
Baig, S.2
Sarwar, M.3
Parvez, S.H.4
-
60
-
-
77951967197
-
NOX activity is increased in mild cognitive impairment
-
A.J.Bruce-Keller, S.Gupta, T.E.Parrino, A.G.Knight, P.J.Ebenezer, A.M.Weidner,. NOX activity is increased in mild cognitive impairment. Antioxid Redox Signal 2010;12:1371–1382.
-
(2010)
Antioxid Redox Signal
, vol.12
, pp. 1371-1382
-
-
Bruce-Keller, A.J.1
Gupta, S.2
Parrino, T.E.3
Knight, A.G.4
Ebenezer, P.J.5
Weidner, A.M.6
-
62
-
-
84940471066
-
Resveratrol inhibits oligomeric Aβ-induced microglial activation via NADPH oxidase
-
Y.Yao, J.Li, Y.Niu, J.Q.Yu, L.Yan, Z.H.Miao,. Resveratrol inhibits oligomeric Aβ-induced microglial activation via NADPH oxidase. Mol Med Rep 2015;12:6133–6139.
-
(2015)
Mol Med Rep
, vol.12
, pp. 6133-6139
-
-
Yao, Y.1
Li, J.2
Niu, Y.3
Yu, J.Q.4
Yan, L.5
Miao, Z.H.6
-
63
-
-
0033771987
-
Selective upregulation of inducible nitric oxide synthase (iNOS) by lipopolysaccharide (LPS) and cytokines in microglia: in vitro and in vivo studies
-
H.Possel, H.Noack, J.Putzke, G.Wolf, H.Sies Selective upregulation of inducible nitric oxide synthase (iNOS) by lipopolysaccharide (LPS) and cytokines in microglia: in vitro and in vivo studies. Glia 2000;32:51–59.
-
(2000)
Glia
, vol.32
, pp. 51-59
-
-
Possel, H.1
Noack, H.2
Putzke, J.3
Wolf, G.4
Sies, H.5
-
64
-
-
84884988774
-
Fisetin averts oxidative stress in pancreatic tissues of streptozotocin-induced diabetic rats
-
G.S.Prasath, C.S.Sundaram, S.P.Subramanian Fisetin averts oxidative stress in pancreatic tissues of streptozotocin-induced diabetic rats. Endocrine 2013;44:359–368.
-
(2013)
Endocrine
, vol.44
, pp. 359-368
-
-
Prasath, G.S.1
Sundaram, C.S.2
Subramanian, S.P.3
-
65
-
-
0032692216
-
Gluthatione level is altered in lymphoblasts from patients with familial Alzheimer’s disease
-
C.Cecchi, S.Latorraca, S.Sorbi, T.Iantomasi, F.Favilli, M.T.Vincenzini, Gluthatione level is altered in lymphoblasts from patients with familial Alzheimer’s disease. Neurosci Lett 1999;275:152–154.
-
(1999)
Neurosci Lett
, vol.275
, pp. 152-154
-
-
Cecchi, C.1
Latorraca, S.2
Sorbi, S.3
Iantomasi, T.4
Favilli, F.5
Vincenzini, M.T.6
-
66
-
-
15044340251
-
Protective effects of oligomers of grape seed polyphenols against beta-amyloid-induced oxidative cell death
-
M.H.Li, J.H.Jang, B.Sun, Y.J.Surh Protective effects of oligomers of grape seed polyphenols against beta-amyloid-induced oxidative cell death. Ann NY Acad Sci2004;1030:317–329.
-
(2004)
Ann NY Acad Sci
, vol.1030
, pp. 317-329
-
-
Li, M.H.1
Jang, J.H.2
Sun, B.3
Surh, Y.J.4
-
67
-
-
0346386580
-
Widespread peroxynitrite-mediated damage in Alzheimer’s disease
-
M.A.Smith, P.L.Richey Harris, L.M.Sayre, J.S.Beckman, G.Perry. Widespread peroxynitrite-mediated damage in Alzheimer’s disease. J Neurosci 1997;17:2653–2657.
-
(1997)
J Neurosci
, vol.17
, pp. 2653-2657
-
-
Smith, M.A.1
Richey Harris, P.L.2
Sayre, L.M.3
Beckman, J.S.4
Perry, G.5
-
68
-
-
0032531735
-
Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation
-
K.Hensley, M.L.Maidt, Z.Yu, H.Sang, W.R.Markesbery, R.A.Floyd Electrochemical analysis of protein nitrotyrosine and dityrosine in the Alzheimer brain indicates region-specific accumulation. J Neurosci 1998;18:8126–8132.
-
(1998)
J Neurosci
, vol.18
, pp. 8126-8132
-
-
Hensley, K.1
Maidt, M.L.2
Yu, Z.3
Sang, H.4
Markesbery, W.R.5
Floyd, R.A.6
-
69
-
-
0037101889
-
Proteomic identification of oxidatively modified proteins in Alzheimer’s disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1
-
A.Castegna, M.Aksenov, M.Aksenova, V.Thongboonkerd, J.B.Klein, W.M.Pierce,. Proteomic identification of oxidatively modified proteins in Alzheimer’s disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. Free Radic Biol Med 2002;33:562–571.
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 562-571
-
-
Castegna, A.1
Aksenov, M.2
Aksenova, M.3
Thongboonkerd, V.4
Klein, J.B.5
Pierce, W.M.6
-
70
-
-
0033133579
-
In vitro and in vivo oxidative stress associated with Alzheimer’s amyloidbeta-peptide (1–42)
-
S.M.Yatin, S.Varadarajan, C.D.Link, D.A.Butterfield In vitro and in vivo oxidative stress associated with Alzheimer’s amyloidbeta-peptide (1–42). Neurobiol Aging 1999;20:325–330.
-
(1999)
Neurobiol Aging
, vol.20
, pp. 325-330
-
-
Yatin, S.M.1
Varadarajan, S.2
Link, C.D.3
Butterfield, D.A.4
-
71
-
-
0036591849
-
Lipid peroxidation and protein oxidation in Alzheimer’s disease brain: potential causes and consequences involving amyloid beta-peptide associated free radical oxidative stress
-
D.A.Butterfield, C.M.Lauderback Lipid peroxidation and protein oxidation in Alzheimer’s disease brain: potential causes and consequences involving amyloid beta-peptide associated free radical oxidative stress. Free Radic Biol Med 2002;32:1050–1060.
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 1050-1060
-
-
Butterfield, D.A.1
Lauderback, C.M.2
|