메뉴 건너뛰기




Volumn 63, Issue 2, 2016, Pages

Regulatory B and T cell responses in patients with autoimmune thyroid disease and healthy controls

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; CD19 ANTIBODY; CD24 ANTIGEN; CD27 ANTIGEN; CD28 ANTIGEN; CD3 ANTIBODY; CD38 ANTIGEN; CD4 ANTIBODY; CD44V ANTIGEN; CD45 ANTIGEN; CD5 ANTIGEN; CPG OLIGODEOXYNUCLEOTIDE; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 35; INTERLEUKIN 4; INTERLEUKIN 6; IONOMYCIN; IXEKIZUMAB; LEUKOSIALIN; PHORBOL 13 ACETATE 12 MYRISTATE; SECUKINUMAB; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA1; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG; AUTOANTIBODY; AUTOANTIGEN; THYROGLOBULIN; THYROTROPIN RECEPTOR;

EID: 84956847008     PISSN: None     EISSN: 22451919     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (46)

References (330)
  • 1
    • 0025358777 scopus 로고
    • Autoimmune diseases: The failure of self tolerance
    • Jun 15
    • Sinha A, Lopez M, McDevitt H. Autoimmune diseases: the failure of self tolerance. Science. 1990 Jun 15;248:1380-8.
    • (1990) Science , vol.248 , pp. 1380-1388
    • Sinha, A.1    Lopez, M.2    McDevitt, H.3
  • 2
    • 0036514975 scopus 로고    scopus 로고
    • Autoimmune thyroid disease: New models of cell death in autoimmunity
    • Mar
    • Stassi G, De Maria R. Autoimmune thyroid disease: new models of cell death in autoimmunity. Nat Rev Immunol. 2002 Mar;2:195-204.
    • (2002) Nat Rev Immunol , vol.2 , pp. 195-204
    • Stassi, G.1    De Maria, R.2
  • 3
    • 20444485767 scopus 로고    scopus 로고
    • Fazekas de St Groth B, Vinuesa CG. Cellular and genetic mechanisms of self tolerance and autoim-munity
    • Jun 2
    • Goodnow CC, Sprent J, Fazekas de St Groth B, Vinuesa CG. Cellular and genetic mechanisms of self tolerance and autoim-munity. Nature. 2005 Jun 2;435:590-7.
    • (2005) Nature , vol.435 , pp. 590-597
    • Goodnow, C.C.1    Sprent, J.2
  • 4
    • 0038725685 scopus 로고    scopus 로고
    • Negative selection-clearing out the bad applesfrom the T-cell repertoire
    • May
    • Palmer E. Negative selection-clearing out the bad apples from the T-cell repertoire. Nat Rev Immunol. 2003 May;3:383-91.
    • (2003) Nat Rev Immunol , vol.3 , pp. 383-391
    • Palmer, E.1
  • 5
    • 84900462616 scopus 로고    scopus 로고
    • Restoring the balance: Immunotherapeutic combinations for autoimmune disease
    • May
    • Smilek DE, Ehlers MR, Nepom GT. Restoring the balance: immunotherapeutic combinations for autoimmune disease. Dis Model Mech. 2014 May;7(5):503-13.
    • (2014) Dis Model Mech , vol.7 , Issue.5 , pp. 503-513
    • Smilek, D.E.1    Ehlers, M.R.2    Nepom, G.T.3
  • 7
    • 25844526684 scopus 로고    scopus 로고
    • Central tolerance:learning self-control in the thymus
    • Oct
    • Hogquist KA, Baldwin TA, Jameson SC. Central tolerance: learning self-control in the thymus. Nat Rev Immunol. 2005 Oct;5:772-82.
    • (2005) Nat Rev Immunol , vol.5 , pp. 772-782
    • Hogquist, K.A.1    Baldwin, T.A.2    Jameson, S.C.3
  • 8
    • 84885613949 scopus 로고    scopus 로고
    • B lymphocytes: Develop-ment, tolerance, and their role in autoimmunity-focus on systemic lupus erythematosus
    • Jan
    • Tobón GJ, Izquierdo JH, Cañas CA. B lymphocytes: develop- ment, tolerance, and their role in autoimmunity-focus on systemic lupus erythematosus. Autoimmune Dis. 2013 Jan;2013:827254.
    • (2013) Autoimmune Dis , vol.2013 , pp. 827254
    • Tobón, G.J.1    Izquierdo, J.H.2    Cañas, C.A.3
  • 9
    • 0029150110 scopus 로고
    • Pillarsarticle: Immunologic self-tolerance maintained by activated Tcells expressing IL-2 receptor α-chains (CD25). Breakdown of asingle mechanism of self-tolerance causes various autoim-mune diseases
    • Apr 1
    • Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Pillars article: immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoim- mune diseases. J Immunol. 1995 Apr 1;155:1151-64.
    • (1995) J Immunol , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 11
    • 30744458329 scopus 로고    scopus 로고
    • A Case for Regulatory B Cells
    • Jan 3
    • Mizoguchi A, Bhan A. A Case for Regulatory B Cells. J Immunol. 2006 Jan 3;176:705-10.
    • (2006) J Immunol , vol.176 , pp. 705-710
    • Mizoguchi, A.1    Bhan, A.2
  • 12
    • 37849044394 scopus 로고    scopus 로고
    • Ehrenstein MR͘ The “short” history of regulatory B cells
    • Jan
    • Mauri C, Ehrenstein MR͘ The “short” history of regulatory B cells. Trends Immunol. 2008 Jan;29:34-40.
    • (2008) Trends Immunol. , vol.29 , pp. 34-40
    • Mauri, C.1
  • 13
    • 79954551032 scopus 로고    scopus 로고
    • Mechanisms of tolerance
    • May
    • Bluestone JA. Mechanisms of tolerance. Immunol Rev. 2011 May;241:5-19.
    • (2011) Immunol Rev , vol.241 , pp. 5-19
    • Bluestone, J.A.1
  • 14
    • 78649555188 scopus 로고    scopus 로고
    • Immune System - Part II Basis of the immunological response mediated by T and B lymphocytes
    • Júnior DM, Araújo JAP, Catelan TTT, de Souza AWS, Cruvinel W de M, Andrade LEC, et al. Immune System - Part II Basis of the immunological response mediated by T and B lymphocytes. Bras J Rheumatol. 2010;50:552-80.
    • (2010) Bras J Rheumatol , vol.50 , pp. 552-580
    • Júnior, D.M.1    Araújo, J.2    Catelan, T.3    De Souza, A.4    Cruvinel W De, M.5    Rade, L.6
  • 15
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas A, Murphy K, Sher A. Functional diversity of helper T lymphocytes. Nature. 1996;383:787-93.
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.1    Murphy, K.2    Sher, A.3
  • 16
    • 72949107811 scopus 로고    scopus 로고
    • Translational mini-review se-ries on Th17 cells: Function and regulation of human T helper 17 cells in health and disease
    • Feb
    • Crome S, Wang A, Levings M. Translational mini-review se-ries on Th17 cells: function and regulation of human T helper 17 cells in health and disease. Clin Exp Immunol. 2009 Feb;159:109–19.
    • (2009) Clin Exp Immunol , vol.159 , pp. 109-119
    • Crome, S.1    Wang, A.2    Levings, M.3
  • 17
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Jul 1
    • Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coff man RL. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol. 1986 Jul 1;136:2348-57.
    • (1986) J Immunol , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coff Man, R.L.5
  • 18
    • 0024353079 scopus 로고
    • Coffman R͘ THIND TH2 CELLS : Different Patterns of Lymphokine Functional Properties
    • Mosmann TR, Coffman R͘ THI ND TH2 CELLS : Different Patterns of Lymphokine Functional Properties. Annu Rev Immunol. 1989;7:145-73.
    • (1989) Annu Rev Immunol. , vol.7 , pp. 45-73
    • Mosmann, T.R.1
  • 19
    • 0028176719 scopus 로고
    • The role of TH1 and TH2 sub-sets in human infectious diseases. Trends Microbiol
    • Del Prete G, Romagnani S. The role of TH1 and TH2 sub- sets in human infectious diseases. Trends Microbiol. 1994 Jan;2:4-6.
    • (1994) Jan , vol.2 , pp. 4-6
    • Del Prete, G.1    Romagnani, S.2
  • 20
    • 0031172781 scopus 로고    scopus 로고
    • The Th1/Th2 paradigm
    • Jun
    • Romagnani S. The Th1/Th2 paradigm. Immunol Today. 1997 Jun;18:263-6.
    • (1997) Immunol Today , vol.18 , pp. 263-266
    • Romagnani, S.1
  • 21
    • 0034677646 scopus 로고    scopus 로고
    • Novel transcription factor, T-bet, directs Th1 lineage commitment
    • Mar 17
    • Szabo S, Kim S, Costa G, Zhang X, Fathman C, Glimcher L. A novel transcription factor, T-bet, directs Th1 lineage commitment. Cell. 2000 Mar 17;100:655-69.
    • (2000) Cell , vol.100 , pp. 655-669
    • Szabo, S.1    Kim, S.2    Costa, G.3    Zhang, X.4    Fathman, C.5    Glimcher, L.A.6
  • 22
    • 52649167708 scopus 로고    scopus 로고
    • CD4 T cells: Fates, functions, and faults
    • Zhu J, Paul WE. CD4 T cells: fates, functions, and faults. Blood. 2008 Sep 1;112:1557-69.
    • (2008) Blood , vol.112 , pp. 1557-1569
    • Zhu, J.1    Paul, W.E.2
  • 23
    • 77952467331 scopus 로고    scopus 로고
    • Heterogeneity of human effector CD4+ T cells
    • Annunziato F, Romagnani S. Heterogeneity of human effector CD4+ T cells. Arthritis Res Ther. 2009 Jan;11:257.
    • (2009) Arthritis Res Ther , vol.11 , pp. 257
    • Annunziato, F.1    Romagnani, S.2
  • 25
    • 0035877106 scopus 로고    scopus 로고
    • Stat6 Is Neces-sary and Sufficient for IL-4’s Role in Th2 Differentiation and Cell Expansion
    • Jun 15
    • Zhu J, Guo L, Watson CJ, Hu-Li J, Paul WE. Stat6 Is Neces- sary and Sufficient for IL-4’s Role in Th2 Differentiation and Cell Expansion. J Immunol. 2001 Jun 15;166:7276-81.
    • (2001) J Immunol , vol.166 , pp. 7276-7281
    • Zhu, J.1    Guo, L.2    Watson, C.J.3    Hu-Li, J.4    Paul, W.E.5
  • 26
    • 0025082313 scopus 로고
    • Paul W. Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells
    • Le Gros G, Ben-Sasson S, Seder R, Finkelman F, Paul W. Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL- 4-producing cells. J Exp Med. 1990;172:921-9.
    • (1990) J Exp Med , vol.172 , pp. 921-929
    • Le Gros, G.1    Ben-Sasson, S.2    Seder, R.3    Finkelman, F.4
  • 27
    • 0025222698 scopus 로고
    • IL-4 directs the development of Th2-like helper effectors
    • Dec 1
    • Swain SL, Weinberg A, English M, Huston G. IL-4 directs the development of Th2-like helper effectors. J Immunol. 1990 Dec 1;145:3796-806.
    • (1990) J Immunol , vol.145 , pp. 3796-3806
    • Swain, S.L.1    Weinberg, A.2    English, M.3    Huston, G.4
  • 28
  • 29
    • 12344269852 scopus 로고    scopus 로고
    • T helper cell fate specified by kinase-mediated interaction of T-bet with GATA-3
    • Jan
    • Hwang ES, Szabo SJ, Schwartzberg PL, Glimcher LH. T helper cell fate specified by kinase-mediated interaction of T- bet with GATA-3. Science. 2005 Jan 21;307:430-3.
    • (2005) Science , vol.307 , pp. 430-433
    • Hwang, E.S.1    Szabo, S.J.2    Schwartzberg, P.L.3    Glimcher, L.H.4
  • 30
    • 0037342749 scopus 로고    scopus 로고
    • GATA-3 sup-presses Th1 development by downregulation of Stat4 and not through effects on IL-12Rbeta2 chain or T-bet
    • Mar
    • Usui T, Nishikomori R, Kitani A, Strober W. GATA-3 sup- presses Th1 development by downregulation of Stat4 and not through effects on IL-12Rbeta2 chain or T-bet. Immunity. 2003 Mar;18:415-28.
    • (2003) Immunity , vol.18 , pp. 415-428
    • Usui, T.1    Nishikomori, R.2    Kitani, A.3    Strober, W.4
  • 31
    • 33645065358 scopus 로고    scopus 로고
    • T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription
    • Mar 20
    • Usui T, Preiss JC, Kanno Y, Yao ZJ, Bream JH, O’Shea JJ, et al. T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription. J Exp Med. 2006 Mar 20;203:755-66.
    • (2006) J Exp Med , vol.203 , pp. 755-766
    • Usui, T.1    Preiss, J.C.2    Kanno, Y.3    Yao, Z.J.4    Bream, J.H.5    O’Shea, J.J.6
  • 32
    • 0028593518 scopus 로고
    • Regulation of the development of type 2 T-helper cells in allergy
    • Dec
    • Romagnani S. Regulation of the development of type 2 T- helper cells in allergy. Curr Opin Immunol. 1994 Dec;6:838-46.
    • (1994) Curr Opin Immunol , vol.6 , pp. 838-846
    • Romagnani, S.1
  • 33
    • 0037449737 scopus 로고    scopus 로고
    • Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
    • Aggarwal S, Ghilardi N, Xie M-H, de Sauvage FJ, Gurney AL. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J Biol Chem. 2003 Jan 17;278:1910-4.
    • (2003) J Biolchem , vol.278 , pp. 1910-1914
    • Aggarwal, S.1    Ghilardi, N.2    Xie, M.-H.3    De Sauvage, F.J.4    Gurney, A.L.5
  • 34
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • Nov
    • Harrington LE, Hatton RD, Mangan PR, Turner H, Murphy TL, Murphy KM, et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol. 2005 Nov;6:1123-32.
    • (2005) Nat Immunol , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3    Turner, H.4    Murphy, T.L.5    Murphy, K.M.6
  • 35
    • 84866749073 scopus 로고    scopus 로고
    • De-fining the human T helper 17 cell phenotype. Trends Immu-nol
    • Oct
    • Annunziato F, Cosmi L, Liotta F, Maggi E, Romagnani S. De- fining the human T helper 17 cell phenotype. Trends Immu- nol. Elsevier Ltd; 2012 Oct;33:505-12.
    • (2012) Elsevier Ltd , vol.33 , pp. 505-512
    • Annunziato, F.1    Cosmi, L.2    Liotta, F.3    Maggi, E.4    Romagnani, S.5
  • 36
    • 33847667225 scopus 로고    scopus 로고
    • The role of Thelper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease
    • Apr
    • Afzali B, Lombardi G, Lechler R, Lord G. The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin Exp Immunol. 2007 Apr;148:32-46.
    • (2007) Clin Exp Immunol , vol.148 , pp. 32-46
    • Afzali, B.1    Lombardi, G.2    Lechler, R.3    Lord, G.4
  • 38
    • 42449129284 scopus 로고    scopus 로고
    • Th17 cells: A third subset of CD4+ T effector cells involved in organ-specific autoimmunity
    • Mar
    • Kurts C. Th17 cells: a third subset of CD4+ T effector cells involved in organ-specific autoimmunity. Nephrol Dial Transplant. 2008 Mar;23:816-9.
    • (2008) Nephrol Dial Transplant , vol.23 , pp. 816-819
    • Kurts, C.1
  • 39
    • 77955298749 scopus 로고    scopus 로고
    • Differentiation Imbalance of Th1/ Th17 in Peripheral Blood Mononuclear Cells Might Contribute to Pathogenesis of Hashimoto’s Thyroiditis
    • Shi Y, Wang H, Su Z, Chen J, Xue Y, Wang S, et al. Differentiation Imbalance of Th1/ Th17 in Peripheral Blood Mononuclear Cells Might Contribute to Pathogenesis of Hashimoto’s Thyroiditis. Scand J Immunol. 2010;72:250-5.
    • (2010) Scand J Immunol , vol.72 , pp. 250-255
    • Shi, Y.1    Wang, H.2    Su, Z.3    Chen, J.4    Xue, Y.5    Wang, S.6
  • 40
    • 67650345273 scopus 로고    scopus 로고
    • Increases of the Th1-Th2 Cell Ratio in Severe Hashimoto’s Disease and in the Proportion of Th17 Cells in Intractable Graves
    • Nanba T, Watanabe M, Inoue N, Iwatani Y. Increases of the Th1-Th2 Cell Ratio in Severe Hashimoto’s Disease and in the Proportion of Th17 Cells in Intractable Graves’ Disease͘ Thyroid. 2009;19:495-501.
    • (2009) Disease͘ Thyroid , vol.19 , pp. 495-501
    • Nanba, T.1    Watanabe, M.2    Inoue, N.3    Iwatani, Y.4
  • 43
    • 34548125305 scopus 로고    scopus 로고
    • Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
    • Acosta-Rodriguez E V, Napolitani G, Lanzavecchia A, Sal- lusto F. Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat Immunol. 2007 Sep;8:942-9.
    • (2007) Nat Immunol , vol.8 , pp. 942-949
    • Acosta-Rodriguez, E.V.1    Napolitani, G.2    Lanzavecchia, A.3    Sal- Lusto, F.4
  • 44
    • 44049104564 scopus 로고    scopus 로고
    • The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
    • Jun
    • Manel N, Unutmaz D, Littman DR. The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat Immunol. 2008 Jun;9:641-9.
    • (2008) Nat Immunol , vol.9 , pp. 641-649
    • Manel, N.1    Unutmaz, D.2    Littman, D.R.3
  • 46
    • 44049102724 scopus 로고    scopus 로고
    • A critical function for transforming growth factorbeta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)-17 responses
    • Volpe E, Servant N, Zollinger R, Bogiatzi SI, Hupé P, Barillot E, et al. A critical function for transforming growth factor beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)-17 responses. Nat Immunol. 2008 Jul;9:650-7.
    • (2008) Nat Immunol , vol.9 , pp. 650-657
    • Volpe, E.1    Servant, N.2    Zollinger, R.3    Bogiatzi, S.I.4    Hupé, P.5    Barillot, E.6
  • 47
    • 44049108877 scopus 로고    scopus 로고
    • Veldhoen M͘ Differentiation ofhuman TH -17 cells does require TGF- β !
    • O’Garra, Stockinger B, Veldhoen M͘ Differentiation of human TH -17 cells does require TGF- β ! Nat Immunol. 2008;9:588-90.
    • (2008) Nat Immunol. , vol.9 , pp. 588-590
    • O’Garra, S.B.1
  • 48
    • 60549094470 scopus 로고    scopus 로고
    • TGF-beta indirectly favors the development of human Th17 cells by inhibiting Th1 cells
    • Jan
    • Santarlasci V, Maggi L, Capone M, Frosali F, Querci V, De Palma R, et al. TGF-beta indirectly favors the development of human Th17 cells by inhibiting Th1 cells. Eur J Immunol. 2009 Jan;39:207-15.
    • (2009) Eur J Immunol , vol.39 , pp. 207-215
    • Santarlasci, V.1    Maggi, L.2    Capone, M.3    Frosali, F.4    Querci, V.5    De Palma, R.6
  • 49
    • 33748588423 scopus 로고    scopus 로고
    • The orphan nuclear receptor RORgammat di-rects the differentiation program of proinflammatory IL-17+ T helper cells
    • Sep 22
    • Ivanov II, McKenzie BS, Zhou L, Tadokoro CE, Lepelley A, Lafaille JJ, et al. The orphan nuclear receptor RORgammat di- rects the differentiation program of proinflammatory IL-17+ T helper cells. Cell. 2006 Sep 22;126:1121-33.
    • (2006) Cell , vol.126 , pp. 1121-1133
    • Ivanov, I.I.1    McKenzie, B.S.2    Zhou, L.3    Tadokoro, C.E.4    Lepelley, A.5    Lafaille, J.J.6
  • 50
    • 67649522177 scopus 로고    scopus 로고
    • RORC2: The master of human Th17 cell programming
    • Unutmaz D. RORC2: the master of human Th17 cell programming. Eur J Immunol. 2009 Jun;39:1452-5.
    • (2009) Eur J Immunol , vol.39 , pp. 1452-1455
    • Unutmaz, D.1
  • 51
    • 27544465354 scopus 로고    scopus 로고
    • A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
    • Park H, Li Z, Yang X, Chang S, Nurieva R, Wang Y, et al. A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol. 2005;6:1133-41.
    • (2005) Nat Immunol , vol.6 , pp. 1133-1141
    • Park, H.1    Li, Z.2    Yang, X.3    Chang, S.4    Nurieva, R.5    Wang, Y.6
  • 53
    • 0037364804 scopus 로고    scopus 로고
    • Natural versus adaptive regulatory T cells
    • Mar
    • Bluestone JA, Abbas AK. Natural versus adaptive regulatory T cells. Nat Rev Immunol. 2003 Mar;3:253-7.
    • (2003) Nat Rev Immunol , vol.3 , pp. 253-257
    • Bluestone, J.A.1    Abbas, A.K.2
  • 54
    • 49849094011 scopus 로고    scopus 로고
    • Natural and TGF-beta-in-duced Foxp3(+)CD4(+) CD25(+) regulatory T cells are not mirror images of each other
    • Sep
    • Horwitz DA, Zheng SG, Gray JD. Natural and TGF-beta-in- duced Foxp3(+)CD4(+) CD25(+) regulatory T cells are not mirror images of each other. Trends Immunol. 2008 Sep;29:429-35.
    • (2008) Trends Immunol , vol.29 , pp. 429-435
    • Horwitz, D.A.1    Zheng, S.G.2    Gray, J.D.3
  • 55
    • 0037385314 scopus 로고    scopus 로고
    • An essential role for Scurfin in CD4+CD25+ T regulatory cells
    • Apr
    • Khattri R, Cox T, Yasayko S-A, Ramsdell F. An essential role for Scurfin in CD4+CD25+ T regulatory cells. Nat Immunol.2003 Apr;4:337-42.
    • (2003) Nat Immunol , vol.4 , pp. 337-342
    • Khattri, R.1    Cox, T.2    Yasayko, S.-A.3    Ramsdell, F.4
  • 56
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Apr
    • Fontenot JD, Gavin MA, Rudensky AY. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol. 2003 Apr;4:330-6.
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 57
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Feb 14
    • Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor Foxp3. Science. 2003 Feb 14;299:1057-61.
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 58
    • 0041931076 scopus 로고    scopus 로고
    • Foxp3 and Natural Regulatory TCells : Key to a Cell Lineage ?
    • Ramsdell F, Celltech R. Foxp3 and Natural Regulatory T Cells : Key to a Cell Lineage ? Immunity͘ 2003;19:165-8
    • (2003) Immunity͘ , vol.19 , pp. 165-168
    • Ramsdell, F.1    Celltech, R.2
  • 60
    • 0029120245 scopus 로고
    • CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation
    • Krummel MF, Allison JP. CD28 and CTLA-4 have opposing effects on the response of T cells to stimulation. J Exp Med. 1995;182:459-65.
    • (1995) J Exp Med , vol.182 , pp. 459-465
    • Krummel, M.F.1    Allison, J.P.2
  • 61
    • 0031861620 scopus 로고    scopus 로고
    • Negative regulation of T cell activation
    • Saito T. Negative regulation of T cell activation. Curr Opin Immunol. 1998;10:313-21.
    • (1998) Curr Opin Immunol , vol.10 , pp. 313-321
    • Saito, T.1
  • 62
    • 0028819315 scopus 로고
    • CD80 (B7) and CD86 (B70) provide similar cost-imulatory signals for T cell proliferation, cytokine production and generation of CTL
    • Lanier LL, Fallon SO, Somoza C, Phillips JH, Linsley PS, Oku- mura K, et al. CD80 (B7) and CD86 (B70) provide similar cost- imulatory signals for T cell proliferation, cytokine production and generation of CTL. J Immunol. 1995;154:97-105.
    • (1995) J Immunol , vol.154 , pp. 97-105
    • Lanier, L.L.1    Fallon, S.O.2    Somoza, C.3    Phillips, J.H.4    Linsley, P.S.5    Oku- Mura, K.6
  • 63
    • 27544481941 scopus 로고    scopus 로고
    • A function for interleukin 2 in Foxp3-expressing regulatory T cells
    • Nov
    • Fontenot JD, Rasmussen JP, Gavin MA, Rudensky AY. A function for interleukin 2 in Foxp3-expressing regulatory T cells. Nat Immunol. 2005 Nov;6:1142-51.
    • (2005) Nat Immunol , vol.6 , pp. 1142-1151
    • Fontenot, J.D.1    Rasmussen, J.P.2    Gavin, M.A.3    Rudensky, A.Y.4
  • 64
    • 2442637772 scopus 로고    scopus 로고
    • CuttingEdge: IL-2 Is Critically Required for the In Vitro Activation ofCD4+CD25+ T Cell Suppressor Function
    • Thornton A, Donovan E, Piccirillo C, Shevach E. Cutting Edge: IL-2 Is Critically Required for the In Vitro Activation of CD4+CD25+ T Cell Suppressor Function. J Immunol. 2004 May 20;172:6519-23.
    • (2004) J Immunol , vol.172 , pp. 6519-6523
    • Thornton, A.1    Donovan, E.2    Piccirillo, C.3    Shevach, E.4
  • 65
    • 0031821875 scopus 로고    scopus 로고
    • CD4+CD25+ Immunoregulatory T cells suppress polyclonal T cell activation in vitro by in-hibiting interleuki 2 production
    • Thornton AM, Shevach EM. CD4+CD25+ Immunoregulatory T cells suppress polyclonal T cell activation in vitro by in- hibiting interleuki 2 production. J Exp Med. 1998;188:287-96.
    • (1998) J Exp Med , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 66
    • 1642453559 scopus 로고    scopus 로고
    • Specialization in tolerance: Innate CD4+CD25+ versus acquired TR1 and TH3 regulatory T cells
    • Jan 15
    • Cottrez F, Groux H. Specialization in tolerance: innate CD4+CD25+ versus acquired TR1 and TH3 regulatory T cells. Transplantation. 2004 Jan 15;77:S12-S15.
    • (2004) Transplantation , vol.77 , pp. S12-S15
    • Cottrez, F.1    Groux, H.2
  • 67
  • 69
    • 0242412365 scopus 로고    scopus 로고
    • A Comparative Study between T Regulatory Type 1 and CD4+CD25+ T Cells in the Control of Inflammation
    • Foussat A, Cottrez F, Brun V, Fournier N, Breittmayer J, Groux H. A Comparative Study between T Regulatory Type 1 and CD4+CD25+ T Cells in the Control of Inflammation. J Immunol. 2003 Nov 7;171:5018-26.
    • (2003) J Immunol , vol.171 , pp. 5018-5026
    • Foussat, A.1    Cottrez, F.2    Brun, V.3    Fournier, N.4    Breittmayer, J.5    Groux, H.6
  • 70
    • 84859390119 scopus 로고    scopus 로고
    • Induced CD4+Foxp3+ regulatory T cells in immune tolerance
    • Bilate AM, Lafaille JJ. Induced CD4+Foxp3+ regulatory T cells in immune tolerance. Annu Rev Immunol. 2012 Jan;30:733-58.
    • (2012) Annu Rev Immunol , vol.30 , pp. 733-758
    • Bilate, A.M.1    Lafaille, J.J.2
  • 71
    • 12844274909 scopus 로고    scopus 로고
    • Differentiation of Tr1 cells by immature den-dritic cells requires IL-10 but not CD25+CD4+ Tr cells
    • Feb 1
    • Levings MK, Gregori S, Tresoldi E, Cazzaniga S, Bonini C, Roncarolo MG. Differentiation of Tr1 cells by immature den- dritic cells requires IL-10 but not CD25+CD4+ Tr cells. Blood. 2005 Feb 1;105:1162-9.
    • (2005) Blood , vol.105 , pp. 1162-1169
    • Levings, M.K.1    Gregori, S.2    Tresoldi, E.3    Cazzaniga, S.4    Bonini, C.5    Roncarolo, M.G.6
  • 72
    • 0038617545 scopus 로고    scopus 로고
    • The complex role of interleukin-10 in autoimmunity
    • Jun
    • Groux H, Cottrez F. The complex role of interleukin-10 in autoimmunity. J Autoimmun. 2003 Jun;20:281-5.
    • (2003) J Autoimmun , vol.20 , pp. 281-285
    • Groux, H.1    Cottrez, F.2
  • 73
    • 0347895101 scopus 로고    scopus 로고
    • Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype
    • Kemper C, Chan AC, Green JM, Brett KA, Murphy KM, At- kinson JP. Activation of human CD4+ cells with CD3 and CD46 induces a T-regulatory cell 1 phenotype. Nature. 2003;421:388-92.
    • (2003) Nature , vol.421 , pp. 388-392
    • Kemper, C.1    Chan, A.C.2    Green, J.M.3    Brett, K.A.4    Murphy, K.M.5    At- Kinson, J.P.6
  • 78
    • 84885457151 scopus 로고    scopus 로고
    • TGF-β: Guardian of T cell function
    • Oct 15
    • Oh SA, Li MO. TGF-β: guardian of T cell function. J Immunol. 2013 Oct 15;191:3973-9.
    • (2013) J Immunol , vol.191 , pp. 3973-3979
    • Oh, S.A.1    Li, M.O.2
  • 79
    • 65549123867 scopus 로고    scopus 로고
    • Natural and adaptive foxp3+ regulatory T cells: More of the same or a division of la-bor? Immunity
    • May
    • Curotto de Lafaille MA, Lafaille JJ. Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of la- bor? Immunity. Elsevier Inc.; 2009 May;30:626-35.
    • (2009) Elsevier Inc. , vol.30 , pp. 626-635
    • Curotto De Lafaille, M.A.1    Lafaille, J.J.2
  • 80
    • 0035806244 scopus 로고    scopus 로고
    • Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood
    • Jun 4
    • Dieckmann D, Plottner H, Berchtold S, Berger T, Schuler G. Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. J Exp Med. 2001 Jun 4;193:1303-10.
    • (2001) J Exp Med , vol.193 , pp. 1303-1310
    • Dieckmann, D.1    Plottner, H.2    Berchtold, S.3    Berger, T.4    Schuler, G.5
  • 82
    • 70049118519 scopus 로고    scopus 로고
    • Regula-tory T cell suppression is potentiated by target T cells in a cell contact, IL-35- and IL-10-dependent manner
    • May 15
    • Collison LW, Pillai MR, Chaturvedi V, Vignali DAA. Regula- tory T cell suppression is potentiated by target T cells in a cell contact, IL-35- and IL-10-dependent manner. J Immunol. 2009 May 15;182:6121-8.
    • (2009) J Immunol , vol.182 , pp. 6121-6128
    • Collison, L.W.1    Pillai, M.R.2    Chaturvedi, V.3    Vignali, D.A.A.4
  • 83
    • 0346969978 scopus 로고    scopus 로고
    • Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4 + CD25- T cells
    • Walker MR, Kasprowicz DJ, Gersuk VH, Bènard A, Landeghen M Van, Buckner JH, et al. Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4 + CD25- T cells. J Clin Invest. 2003;112:1437-43.
    • (2003) J Clin Invest , vol.112 , pp. 1437-1443
    • Walker, M.R.1    Kasprowicz, D.J.2    Gersuk, V.H.3    Bènard, A.4    Landeghen, M.5    Van, B.J.6
  • 84
    • 15244354491 scopus 로고    scopus 로고
    • De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25-cells
    • Walker MR, Carson BD, Nepom GT, Ziegler SF, Buckner JH. De novo generation of antigen-specific CD4+CD25+ regulatory T cells from human CD4+CD25-cells. Proc Natl Acad Sci USA. 2005;102:4103-8.
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4103-4108
    • Walker, M.R.1    Carson, B.D.2    Nepom, G.T.3    Ziegler, S.F.4    Buckner, J.H.5
  • 85
    • 1242290580 scopus 로고    scopus 로고
    • Natu-ral and Induced CD4+CD25+ Cells Educate CD4+CD25- Cells to Develop Suppressive Activity: The Role of IL-2, TGF-beta, and IL-10
    • Apr 20
    • Zheng SG, Wang JH, Gray JD, Soucier H, Horwitz DA. Natu- ral and Induced CD4+CD25+ Cells Educate CD4+CD25- Cells to Develop Suppressive Activity: The Role of IL-2, TGF-beta, and IL-10. J Immunol. 2004 Apr 20;172:5213-21.
    • (2004) J Immunol , vol.172 , pp. 5213-5221
    • Zheng, S.G.1    Wang, J.H.2    Gray, J.D.3    Soucier, H.4    Horwitz, D.A.5
  • 87
    • 34948875308 scopus 로고    scopus 로고
    • Immune dysregulation, polyendo crinopathy, enteropathy, X-linked: Forkhead box protein 3mutations and lack of regulatory T cells
    • Oct
    • Torgerson TR, Ochs HD. Immune dysregulation, polyendo crinopathy, enteropathy, X-linked: forkhead box protein 3 mutations and lack of regulatory T cells. J Allergy Clin Immunol. 2007 Oct;120:744-50.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 744-750
    • Torgerson, T.R.1    Ochs, H.D.2
  • 88
    • 18244378309 scopus 로고    scopus 로고
    • Novel mutations of FOXP3 in two Japanese pa-tients with immune dysregulation, polyendocrinopathy, en-teropathy, X linked syndrome (IPEX)
    • Dec
    • Kobayashi I, Shiari R, Yamada M, Kawamura N, Okano M, Yara A, et al. Novel mutations of FOXP3 in two Japanese pa- tients with immune dysregulation, polyendocrinopathy, en- teropathy, X linked syndrome (IPEX). J Med Genet. 2001 Dec;38:874-6.
    • (2001) J Med Genet , vol.38 , pp. 874-876
    • Kobayashi, I.1    Shiari, R.2    Yamada, M.3    Kawamura, N.4    Okano, M.5    Yara, A.6
  • 89
    • 84859953961 scopus 로고    scopus 로고
    • FoxP3 mRNA splice forms in synovial CD4+ Tcells in rheumatoid arthritis and psoriatic arthritis
    • May
    • Ryder LR, Bartels EM, Woetmann A, Madsen HO, Odum N, Bliddal H, et al. FoxP3 mRNA splice forms in synovial CD4+ T cells in rheumatoid arthritis and psoriatic arthritis. APMIS. 2012 May;120:387-96.
    • (2012) APMIS , vol.120 , pp. 387-396
    • Ryder, L.R.1    Bartels, E.M.2    Woetmann, A.3    Madsen, H.O.4    Odum, N.5    Bliddal, H.6
  • 90
    • 33748751458 scopus 로고    scopus 로고
    • Splice variants of human FOXP3 are functional inhibitors ofhuman CD4+ T-cell activation
    • Smith E, Finney H, Nesbitt A, Ramsdell F, Robinson M. Splice variants of human FOXP3 are functional inhibitors of human CD4+ T-cell activation. Immunology. 2006;119:203-11.
    • (2006) Immunology , vol.119 , pp. 203-211
    • Smith, E.1    Finney, H.2    Nesbitt, A.3    Ramsdell, F.4    Robinson, M.5
  • 92
    • 0035813231 scopus 로고    scopus 로고
    • Scurfin (FOXP3) acts as a repressor of transcription and regu-lates T cell activation
    • Oct 5
    • Schubert L, Jeffery E, Zhang Y, Ramsdell F, Ziegler S. Scurfin (FOXP3) acts as a repressor of transcription and regu- lates T cell activation. J Biol Chem. 2001 Oct 5;276:37672-9.
    • (2001) J Biol Chem , vol.276 , pp. 37672-37679
    • Schubert, L.1    Jeffery, E.2    Zhang, Y.3    Ramsdell, F.4    Ziegler, S.5
  • 93
    • 17044393922 scopus 로고    scopus 로고
    • Foxp3 interacts with nu-clear factor of activated T cells and NF-kappa B to repress cy-tokine gene expression and effector functions of T helpercells
    • Apr 5
    • Bettelli E, Dastrange M, Oukka M. Foxp3 interacts with nu- clear factor of activated T cells and NF-kappa B to repress cy- tokine gene expression and effector functions of T helper cells. Proc Natl Acad Sci U S A. 2005 Apr 5;102:5138-43.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 5138-5143
    • Bettelli, E.1    Dastrange, M.2    Oukka, M.3
  • 94
    • 44449131480 scopus 로고    scopus 로고
    • Isoform-Specific Inhibi-tion of ROR-alpha Mediated Transcriptional Activation by Human FOXP3
    • Mar 19
    • Du J, Huang C, Zhou B, Ziegler S. Isoform-Specific Inhibi- tion of ROR-alpha Mediated Transcriptional Activation by Human FOXP3. J Immunol. 2008 Mar 19;180:4785-92.
    • (2008) J Immunol , vol.180 , pp. 4785-4792
    • Du, J.1    Huang, C.2    Zhou, B.3    Ziegler, S.4
  • 95
    • 43449135305 scopus 로고    scopus 로고
    • TGF- β -induced Foxp3 inhibits Th17 cell differentia-tion by antagonizing RORγt function
    • Zhou L, Lopes JE, Chong MMW, Ivanov II, Min R, Victoria GD, et al. TGF- β -induced Foxp3 inhibits Th17 cell differentia- tion by antagonizing RORγt function. Nature. 2008;453:236-40.
    • (2008) Nature , vol.453 , pp. 236-240
    • Zhou, L.1    Lopes, J.E.2    Chong, M.3    Ivanov, I.I.4    Min, R.5    Victoria, G.D.6
  • 97
    • 72949119542 scopus 로고    scopus 로고
    • Trans-lational mini-review series on Th17 cells: Induction of inter-leukin-17 production by regulatory T cells
    • Feb
    • Afzali B, Mitchell P, Lechler RI, John S, Lombardi G. Trans- lational mini-review series on Th17 cells: induction of inter- leukin-17 production by regulatory T cells. Clin Exp Immunol. 2009 Feb;159:120-30.
    • (2009) Clin Exp Immunol , vol.159 , pp. 120-130
    • Afzali, B.1    Mitchell, P.2    Lechler, R.I.3    John, S.4    Lombardi, G.5
  • 99
    • 84871312272 scopus 로고    scopus 로고
    • Distinctive features of classic and nonclassic (Th17 derived) human Th1 cells
    • Dec
    • Maggi L, Santarlasci V, Capone M, Rossi MC, Querci V, Mazzoni A, et al. Distinctive features of classic and nonclassic (Th17 derived) human Th1 cells. Eur J Immunol. 2012 Dec;42:3180-8.
    • (2012) Eur J Immunol , vol.42 , pp. 3180-3188
    • Maggi, L.1    Santarlasci, V.2    Capone, M.3    Rossi, M.C.4    Querci, V.5    Mazzoni, A.6
  • 102
    • 66649115650 scopus 로고    scopus 로고
    • Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the T(H)17 lineage-specific transcription factor RORgammat
    • May 26
    • Ayyoub M, Deknuydt F, Raimbaud I, Dousset C, Leveque L, Bioley G, et al. Human memory FOXP3+ Tregs secrete IL-17 ex vivo and constitutively express the T(H)17 lineage-specific transcription factor RORgammat. Proc Natl Acad Sci U S A. 2009 May 26;106:8635-40.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 8635-8640
    • Ayyoub, M.1    Deknuydt, F.2    Raimbaud, I.3    Dousset, C.4    Leveque, L.5    Bioley, G.6
  • 103
    • 65549088243 scopus 로고    scopus 로고
    • IL-17-producing human peripheral regulatory T cells retain suppressive function
    • 2009Apr 30
    • Beriou G, Costantino CM, Ashley CW, Yang L, Kuchroo VK, Baecher-Allan C, et al. IL-17-producing human peripheral regulatory T cells retain suppressive function. Blood. 2009 Apr 30;113:4240-9.
    • Blood , vol.113 , pp. 4240-4249
    • Beriou, G.1    Costantino, C.M.2    Ashley, C.W.3    Yang, L.4    Kuchroo, V.K.5    Baecher-Allan, C.6
  • 105
    • 0035056376 scopus 로고    scopus 로고
    • B cell development pathways
    • Hardy R, Hayakawa K. B cell development pathways. Annu Rev Immunol. 2001;19:595-621.
    • (2001) Annu Rev Immunol , vol.19 , pp. 595-621
    • Hardy, R.1    Hayakawa, K.2
  • 106
    • 47249099558 scopus 로고    scopus 로고
    • B lymphocytes: How they develop and function
    • Sep 1
    • LeBien TW, Tedder TF. B lymphocytes: how they develop and function. Blood. 2008 Sep 1;112:1570-80.
    • (2008) Blood , vol.112 , pp. 1570-1580
    • Lebien, T.W.1    Tedder, T.F.2
  • 107
    • 0021956416 scopus 로고
    • Antigen-Specific Interaction between T and B Cells
    • Lanzavecchia A. Antigen-Specific Interaction between T and B Cells. Nature. 1985;314:537-9.
    • (1985) Nature , vol.314 , pp. 537-539
    • Lanzavecchia, A.1
  • 108
    • 0035367804 scopus 로고    scopus 로고
    • B lymphocyte activation by contact-mediated interactions with T lymphocytes
    • Jun
    • Bishop G, Hostager B. B lymphocyte activation by contact-mediated interactions with T lymphocytes. Curr Opin Immunol. 2001 Jun;13:278-85.
    • (2001) Curr Opin Immunol , vol.13 , pp. 278-285
    • Bishop, G.1    Hostager, B.2
  • 110
    • 0026007066 scopus 로고
    • The development and repertoire of B-1 cells (CD5 B cells)
    • Kantor AB. The development and repertoire of B-1 cells (CD5 B cells). Immunol Today. 1991;12:389-91.
    • (1991) Immunol Today , vol.12 , pp. 389-391
    • Kantor, A.B.1
  • 111
  • 112
    • 0032445137 scopus 로고    scopus 로고
    • A critical role of natural immunoglobulin M in immediate defenseagainst systemic bacterial infection
    • Dec 21
    • Boes M, Prodeus A, Schmidt T, Carroll M, Chen J. A critical role of natural immunoglobulin M in immediate defense against systemic bacterial infection. J Exp Med. 1998 Dec 21;188:2381-6.
    • (1998) J Exp Med , vol.188 , pp. 2381-2386
    • Boes, M.1    Prodeus, A.2    Schmidt, T.3    Carroll, M.4    Chen, J.5
  • 113
    • 0034679710 scopus 로고    scopus 로고
    • B-1 and B-2 cell-derived immunoglobulin M antibodies are nonredundant components of the protective response to influenza virus infection
    • Jul 17
    • Baumgarth N, Herman O, Jager G, Brown L, Herzenberg L, Chen J. B-1 and B-2 cell-derived immunoglobulin M antibodies are nonredundant components of the protective response to influenza virus infection. J Exp Med. 2000 Jul 17;192:271-80.
    • (2000) J Exp Med , vol.192 , pp. 271-280
    • Baumgarth, N.1    Herman, O.2    Jager, G.3    Brown, L.4    Herzenberg, L.5    Chen, J.6
  • 114
    • 33747761954 scopus 로고    scopus 로고
    • B-1 B Cell Development
    • Aug 18
    • Hardy RR. B-1 B Cell Development. J Immunol. 2006 Aug 18;176:2749-54.
    • (2006) J Immunol , vol.176 , pp. 2749-2754
    • Hardy, R.R.1
  • 115
    • 34548742977 scopus 로고    scopus 로고
    • Reciprocal generation of Th1/Th17 and T(Reg) cells by B1 and B2 B cells
    • Sep
    • Zhong X, Gao W, Degauque N, Bai C, Lu Y, Kenny J, et al. Reciprocal generation of Th1/Th17 and T(reg) cells by B1 and B2 B cells. Eur J Immunol. 2007 Sep;37:2400-4.
    • (2007) Eur J Immunol , vol.37 , pp. 2400-2404
    • Zhong, X.1    Gao, W.2    Degauque, N.3    Bai, C.4    Lu, Y.5    Kenny, J.6
  • 117
    • 35448975223 scopus 로고    scopus 로고
    • Properties and function of polyreactive antibodies and polyreactive antigen-binding cells
    • Zhou Z, Tzioufas AG, Notkins AL. Properties and function of polyreactive antibodies and polyreactive antigen-binding cells. J Autoimmun. 2007;29:219-28.
    • (2007) J Autoimmun , vol.29 , pp. 219-228
    • Zhou, Z.1    Tzioufas, A.G.2    Notkins, A.L.3
  • 119
    • 0025191139 scopus 로고
    • Anti-DNA antibody production by CD5+ and CD5B cells of patients with systemic lupus erythematosus
    • Jan
    • Suzuki N, Sakane T, Engleman E. Anti-DNA antibody production by CD5+ and CD5B cells of patients with systemic lupus erythematosus. J Clin Invest. 1990 Jan;85:238-47.
    • (1990) J Clin Invest , vol.85 , pp. 238-247
    • Suzuki, N.1    Sakane, T.2    Engleman, E.3
  • 120
    • 0023127468 scopus 로고
    • Human lymphocytes making rheumatoid factor and antibody to ssDNA belong to Leu-1+ B-cell subset
    • Apr 3
    • Casali P, Burastero S, Nakamura M, Inghirami G, Notkins A. Human lymphocytes making rheumatoid factor and antibody to ssDNA belong to Leu-1+ B-cell subset. Science. 1987 Apr 3;236:77-81.
    • (1987) Science , vol.236 , pp. 77-81
    • Casali, P.1    Burastero, S.2    Nakamura, M.3    Inghirami, G.4    Notkins, A.5
  • 121
    • 0037114620 scopus 로고    scopus 로고
    • Human CD5 promotes B-cell survival through stimulation of autocrine IL-10 production
    • Gary-Gouy H, Harriague J, Bismuth G, Platzer C, Schmitt C, Dalloul AH. Human CD5 promotes B-cell survival through stimulation of autocrine IL-10 production. Blood. 2002;100:4537-43.
    • (2002) Blood , vol.100 , pp. 4537-4543
    • Gary-Gouy, H.1    Harriague, J.2    Bismuth, G.3    Platzer, C.4    Schmitt, C.5    Dalloul, A.H.6
  • 122
    • 0942290440 scopus 로고    scopus 로고
    • Peripheral development of B cells in mouse and man
    • Feb
    • Carsetti R, Rosado MM, Wardmann H. Peripheral development of B cells in mouse and man. Immunol Rev. 2004 Feb;197:179-91.
    • (2004) Immunol Rev , vol.197 , pp. 179-191
    • Carsetti, R.1    Rosado, M.M.2    Wardmann, H.3
  • 123
    • 0029156872 scopus 로고
    • CD5 expression on B cells may be an activation marker for secretion of anti-myelin antibodies in patients with polyneuropathy associated with monoclonal gammopathy
    • Ekerfelt C, Ernerudh J, Solderst G, Vrethem M. CD5 expression on B cells may be an activation marker for secretion of anti-myelin antibodies in patients with polyneuropathy associated with monoclonal gammopathy. Clin Exp Immunol. 1995;101:346-50.
    • (1995) Clin Exp Immunol , vol.101 , pp. 346-350
    • Ekerfelt, C.1    Ernerudh, J.2    Solderst, G.3    Vrethem, M.4
  • 124
    • 78651509914 scopus 로고    scopus 로고
    • Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+ CD27+ CD43+ CD70-
    • Jan 17
    • Griffin DO, Holodick NE, Rothstein TL. Human B1 cells in umbilical cord and adult peripheral blood express the novel phenotype CD20+ CD27+ CD43+ CD70-. J Exp Med. 2011 Jan 17;208:67-80.
    • (2011) J Exp Med , vol.208 , pp. 67-80
    • Griffin, D.O.1    Holodick, N.E.2    Rothstein, T.L.3
  • 125
    • 0029003671 scopus 로고
    • Transitional B Cells Are the Target of Negative Selection in the B Cell Compartment
    • Carsetti R, Kohler G, Lamers MC. Transitional B Cells Are the Target of Negative Selection in the B Cell Compartment. J Exp Med. 1995;181:2129-40.
    • (1995) J Exp Med , vol.181 , pp. 2129-2140
    • Carsetti, R.1    Kohler, G.2    Lamers, M.C.3
  • 127
    • 0035892228 scopus 로고    scopus 로고
    • Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation
    • Dec 15
    • Allman D, Lindsley R, DeMuth W, Rudd K, Shinton S, Hardy R. Resolution of three nonproliferative immature splenic B cell subsets reveals multiple selection points during peripheral B cell maturation. J Immunol. 2001 Dec 15;167:6834-40.
    • (2001) J Immunol , vol.167 , pp. 6834-6840
    • Allman, D.1    Lindsley, R.2    Demuth, W.3    Rudd, K.4    Shinton, S.5    Hardy, R.6
  • 128
    • 0036163380 scopus 로고    scopus 로고
    • CD23 defines two distinct subsets of immature B cells which differ in their responses to T cell help signals
    • Feb
    • Chung JB, Sater RA, Fields ML, Erikson J, Monroe JG. CD23 defines two distinct subsets of immature B cells which differ in their responses to T cell help signals. Int Immunol. 2002 Feb;14:157-66.
    • (2002) Int Immunol , vol.14 , pp. 157-166
    • Chung, J.B.1    Sater, R.A.2    Fields, M.L.3    Erikson, J.4    Monroe, J.G.5
  • 129
    • 2242446203 scopus 로고    scopus 로고
    • Transitional type 1 and 2 B lymphocyte subsets are differentially responsive to antigen receptor signaling
    • Dec 13
    • Petro JB, Gerstein RM, Lowe J, Carter RS, Shinners N, Khan WN. Transitional type 1 and 2 B lymphocyte subsets are differentially responsive to antigen receptor signaling. J Biol Chem. 2002 Dec 13;277:48009-19.
    • (2002) J Biol Chem , vol.277 , pp. 48009-48019
    • Petro, J.B.1    Gerstein, R.M.2    Lowe, J.3    Carter, R.S.4    Shinners, N.5    Khan, W.N.6
  • 130
    • 0033526816 scopus 로고    scopus 로고
    • B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals
    • Jul 5
    • Loder F, Mutschler B, Ray R, Paige C, Sideras P, Torres R, et al. B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals. J Exp Med. 1999 Jul 5;190:75-89.
    • (1999) J Exp Med , vol.190 , pp. 75-89
    • Loder, F.1    Mutschler, B.2    Ray, R.3    Paige, C.4    Sideras, P.5    Torres, R.6
  • 131
    • 19344376101 scopus 로고    scopus 로고
    • Identification and characterization of circulating human transitional B cells
    • Jun 1
    • Sims GP, Ettinger R, Shirota Y, Yarboro CH, Illei GG, Lipsky PE. Identification and characterization of circulating human transitional B cells. Blood. 2005 Jun 1;105:4390-8.
    • (2005) Blood , vol.105 , pp. 4390-4398
    • Sims, G.P.1    Ettinger, R.2    Shirota, Y.3    Yarboro, C.H.4    Illei, G.G.5    Lipsky, P.E.6
  • 132
    • 40849145800 scopus 로고    scopus 로고
    • Transitional B cells in humans: Characterizationand insight from B lymphocyte reconstitution after hematopoietic stem cell transplantation
    • Apr
    • Marie-Cardine A, Divay F, Dutot I, Green A, Perdrix A, Boyer O, et al. Transitional B cells in humans: characterization and insight from B lymphocyte reconstitution after hematopoietic stem cell transplantation. Clin Immunol. 2008 Apr;127:14-25.
    • (2008) Clin Immunol , vol.127 , pp. 14-25
    • Marie-Cardine, A.1    Divay, F.2    Dutot, I.3    Green, A.4    Perdrix, A.5    Boyer, O.6
  • 133
    • 72449140060 scopus 로고    scopus 로고
    • Novel human transitional B cell populations revealed by B cell depletion therapy
    • Palanichamy A, Barnard J, Zheng B, Owen T, Quach T, Looney RJ, et al. Novel human transitional B cell populations revealed by B cell depletion therapy. J Immunol. 2009;182:5982-93.
    • (2009) J Immunol , vol.182 , pp. 5982-5993
    • Palanichamy, A.1    Barnard, J.2    Zheng, B.3    Owen, T.4    Quach, T.5    Looney, R.J.6
  • 134
    • 77449159423 scopus 로고    scopus 로고
    • Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells
    • Jan 21
    • Suryani S, Fulcher D a, Santner-Nanan B, Nanan R, Wong M, Shaw PJ, et al. Differential expression of CD21 identifies developmentally and functionally distinct subsets of human transitional B cells. Blood. 2010 Jan 21;115:519-29.
    • (2010) Blood , vol.115 , pp. 519-529
    • Suryani, S.1    Fulcher, D.2    Santner-Nanan, B.3    Nanan, R.4    Wong, M.5    Shaw, P.J.6
  • 135
    • 0035314006 scopus 로고    scopus 로고
    • B1 cells: Similarities and differences with other B cell subsets
    • Apr
    • Martin F, Kearney J. B1 cells: similarities and differences with other B cell subsets. Curr Opin Immunol. 2001 Apr;13:195-201.
    • (2001) Curr Opin Immunol , vol.13 , pp. 195-201
    • Martin, F.1    Kearney, J.2
  • 136
    • 70350515662 scopus 로고    scopus 로고
    • The follicular versus marginal zone B lymphocyte cell fate decision
    • Nov
    • Pillai S, Cariappa A. The follicular versus marginal zone B lymphocyte cell fate decision. Nat Rev Immunol. 2009 Nov;9:767-77.
    • (2009) Nat Rev Immunol , vol.9 , pp. 767-777
    • Pillai, S.1    Cariappa, A.2
  • 137
    • 84872946832 scopus 로고    scopus 로고
    • Marginal zone B cells: Virtues of innatelike antibody-producing lymphocytes
    • Cerutti A, Cols M, Puga I. Marginal zone B cells: virtues of innatelike antibody-producing lymphocytes. Nat Rev Immunol. 2013;13:118-32.
    • (2013) Nat Rev Immunol , vol.13 , pp. 118-132
    • Cerutti, A.1    Cols, M.2    Puga, I.3
  • 138
    • 0033563309 scopus 로고    scopus 로고
    • IgMhigh CD21high Lymphocytes Enriched in the Splenic Marginal Zone Generate Effector Cells More Rapidly Than the Bulk of Follicular B Cells
    • Oliver AM, Martin F, Kearney JF. IgMhigh CD21high Lymphocytes Enriched in the Splenic Marginal Zone Generate Effector Cells More Rapidly Than the Bulk of Follicular B Cells. J Immunol. 1999;162:7198-207.
    • (1999) J Immunol , vol.162 , pp. 7198-7207
    • Oliver, A.M.1    Martin, F.2    Kearney, J.F.3
  • 139
    • 26644456680 scopus 로고    scopus 로고
    • Perisinusoidal B cells in the bone marrow participate in T-independent responses to blood-borne microbes
    • Oct
    • Cariappa A, Mazo IB, Chase C, Shi HN, Liu H, Li Q, et al. Perisinusoidal B cells in the bone marrow participate in T-independent responses to blood-borne microbes. Immunity. 2005 Oct;23:397-407.
    • (2005) Immunity , vol.23 , pp. 397-407
    • Cariappa, A.1    Mazo, I.B.2    Chase, C.3    Shi, H.N.4    Liu, H.5    Li, Q.6
  • 140
    • 1642536499 scopus 로고    scopus 로고
    • Marginal Zone, but Not Follicular B Cells, Are Potent Activators of Naive CD4 T Cells
    • Jan 5
    • Attanavanich K, Kearney J. Marginal Zone, but Not Follicular B Cells, Are Potent Activators of Naive CD4 T Cells. J Immunol. 2004 Jan 5;172:803-11.
    • (2004) J Immunol , vol.172 , pp. 803-811
    • Attanavanich, K.1    Kearney, J.2
  • 141
    • 37349022260 scopus 로고    scopus 로고
    • Antigens take the shuttle
    • Jan
    • Kraal G. Antigens take the shuttle. Nat Immunol. 2008 Jan;9:11-2.
    • (2008) Nat Immunol , vol.9 , pp. 11-12
    • Kraal, G.1
  • 142
    • 37349013401 scopus 로고    scopus 로고
    • Follicular shuttling of marginal zone B cells facilitates antigen transport
    • Cinamon G, Zachariah MA, Lam OM, Foss Jr. FW, Cyster JG. Follicular shuttling of marginal zone B cells facilitates antigen transport. Nat Immunol. 2008;9:54-62.
    • (2008) Nat Immunol , vol.9 , pp. 54-62
    • Cinamon, G.1    Zachariah, M.A.2    Lam, O.M.3    Foss, F.W.4    Cyster, J.G.5
  • 144
    • 0030456897 scopus 로고    scopus 로고
    • Experimental autoimmune encephalomyelitis induction in genetically B celldeficient mice
    • Dec 1
    • Wolf S, Dittel B, Hardardottir F, Janeway C. Experimental autoimmune encephalomyelitis induction in genetically B celldeficient mice. J Exp Med. 1996 Dec 1;184:2271-8.
    • (1996) J Exp Med , vol.184 , pp. 2271-2278
    • Wolf, S.1    Dittel, B.2    Hardardottir, F.3    Janeway, C.4
  • 146
    • 0034013685 scopus 로고    scopus 로고
    • Regulatory role of mature B cells in a murine model of inflammatory bowel disease
    • May
    • Mizoguchi E, Mizoguchi A, Preffer F, Bhan A. Regulatory role of mature B cells in a murine model of inflammatory bowel disease. Int Immunol. 2000 May;12:597-605.
    • (2000) Int Immunol , vol.12 , pp. 597-605
    • Mizoguchi, E.1    Mizoguchi, A.2    Preffer, F.3    Bhan, A.4
  • 147
    • 0036197923 scopus 로고    scopus 로고
    • Chronic Intestinal Inflammatory Condition Generates IL-10-Producing Regulatory B Cell Subset Characterized by CD1d Upregulation
    • Mizoguchi A, Mizoguchi E, Takedatsu H, Blumberg RS, Bhan AK. Chronic Intestinal Inflammatory Condition Generates IL-10-Producing Regulatory B Cell Subset Characterized by CD1d Upregulation. Immunity. 2002;16:219-30.
    • (2002) Immunity , vol.16 , pp. 219-230
    • Mizoguchi, A.1    Mizoguchi, E.2    Takedatsu, H.3    Blumberg, R.S.4    Bhan, A.K.5
  • 148
    • 0037450740 scopus 로고    scopus 로고
    • Prevention of Arthritis by Interleukin 10-producing B Cells
    • Mauri C, Gray D, Mushtaq N, Londei M. Prevention of Arthritis by Interleukin 10-producing B Cells. J Exp Med. 2003;197:489-501.
    • (2003) J Exp Med , vol.197 , pp. 489-501
    • Mauri, C.1    Gray, D.2    Mushtaq, N.3    Londei, M.4
  • 149
    • 84856616941 scopus 로고    scopus 로고
    • Interleukin-10 produced by B cells is crucial for the suppression of Th17/Th1 responses, induction of T regulatory type 1 cells and reduction of collagen-induced arthritis. Arthritis Res Ther
    • Jan
    • Carter NA, Rosser EC, Mauri C. Interleukin-10 produced by B cells is crucial for the suppression of Th17/Th1 responses, induction of T regulatory type 1 cells and reduction of collagen-induced arthritis. Arthritis Res Ther. BioMed Central Ltd; 2012 Jan;14:R32.
    • (2012) Biomed Central Ltd , vol.14
    • Carter, N.A.1    Rosser, E.C.2    Mauri, C.3
  • 150
    • 0026662524 scopus 로고
    • IL-10 Production by CD5 B Cells
    • May 17
    • O’Garra, Howard M. IL-10 Production by CD5 B Cells. Ann N Y Acad Sci. 1992 May 17;651:182-99.
    • (1992) Ann N Y Acad Sci , vol.651 , pp. 182-199
    • O’Garra, H.1
  • 151
    • 74649083783 scopus 로고    scopus 로고
    • CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients
    • Jan 29
    • Blair PA, Noreña LY, Flores-Borja F, Rawlings DJ, Isenberg DA, Ehrenstein MR, et al. CD19(+)CD24(hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic Lupus Erythematosus patients. Immunity. 2010 Jan 29;32:129-40.
    • (2010) Immunity , vol.32 , pp. 129-140
    • Blair, P.A.1    Noreña, L.Y.2    Flores-Borja, F.3    Rawlings, D.J.4    Isenberg, D.A.5    Ehrenstein, M.R.6
  • 152
    • 84855476096 scopus 로고    scopus 로고
    • A small CD11b(+) human B1 cell subpopulation stimulates T cells and is expanded in lupus
    • Dec 19
    • Griffin DO, Rothstein TL. A small CD11b(+) human B1 cell subpopulation stimulates T cells and is expanded in lupus. J Exp Med. 2011 Dec 19;208:2591-8.
    • (2011) J Exp Med , vol.208 , pp. 2591-2598
    • Griffin, D.O.1    Rothstein, T.L.2
  • 153
    • 80052382391 scopus 로고    scopus 로고
    • Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice
    • Ding Q, Yeung M, Camirand G, Zeng Q, Akiba H, Yagita H, et al. Regulatory B cells are identified by expression of TIM-1 and can be induced through TIM-1 ligation to promote tolerance in mice. J Clin Invest. 2011;121:3645-56.
    • (2011) J Clin Invest , vol.121 , pp. 3645-3656
    • Ding, Q.1    Yeung, M.2    Camirand, G.3    Zeng, Q.4    Akiba, H.5    Yagita, H.6
  • 154
    • 78751469622 scopus 로고    scopus 로고
    • Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells
    • Jan 13
    • Iwata Y, Matsushita T, Horikawa M, Dilillo DJ, Yanaba K, Venturi GM, et al. Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells. Blood. 2011 Jan 13;117:530-41.
    • (2011) Blood , vol.117 , pp. 530-541
    • Iwata, Y.1    Matsushita, T.2    Horikawa, M.3    Dilillo, D.J.4    Yanaba, K.5    Venturi, G.M.6
  • 156
    • 84870003475 scopus 로고    scopus 로고
    • Decrease inproportion of CD19+ CD24(Hi) CD27+ B cells and impairmentof their suppressive function in Graves’ disease͘
    • Jan
    • Zha B, Wang L, Liu X, Liu J, Chen Z, Xu J, et al. Decrease in proportion of CD19+ CD24(hi) CD27+ B cells and impairment of their suppressive function in Graves’ disease͘. PLoS One͘ 2012 Jan;7:e49835.
    • (2012) Plos One͘ , vol.7
    • Zha, B.1    Wang, L.2    Liu, X.3    Liu, J.4    Chen, Z.5    Xu, J.6
  • 157
    • 84861724649 scopus 로고    scopus 로고
    • Human CD19+CD25high B regulatory cells suppress proliferation of CD4+ T cells and enhance Foxp3 and CTLA-4 expression in T-regulatory cells
    • Kessel A, Haj T, Peri R, Snir A, Melamed D, Sabo E, et al. Human CD19+CD25high B regulatory cells suppress proliferation of CD4+ T cells and enhance Foxp3 and CTLA-4 expression in T-regulatory cells. Autoimmun Rev. 2012;11:670-7.
    • (2012) Autoimmun Rev , vol.11 , pp. 670-677
    • Kessel, A.1    Haj, T.2    Peri, R.3    Snir, A.4    Melamed, D.5    Sabo, E.6
  • 158
    • 84874720574 scopus 로고    scopus 로고
    • CD19+CD24hiCD38hi B cells maintain regulatory T cells while limiting TH1 and TH17 differentiation
    • Feb 20, ra23
    • Flores-Borja F, Bosma A, Ng D, Reddy V, Ehrenstein MR, Isenberg DA, et al. CD19+CD24hiCD38hi B cells maintain regulatory T cells while limiting TH1 and TH17 differentiation. Sci Transl Med. 2013 Feb 20;5:173ra23.
    • (2013) Sci Transl Med , vol.5 , pp. 173
    • Flores-Borja, F.1    Bosma, A.2    Ng, D.3    Reddy, V.4    Ehrenstein, M.R.5    Isenberg, D.A.6
  • 159
    • 84897848280 scopus 로고    scopus 로고
    • CD24(Hi)CD27(+) B cells from patients with allergic asthma have impaired regulatory activity in response to lipopolysaccharide
    • Apr
    • Van der Vlugt L, Mlejnek E, Ozir-Fazalalikhan A, Janssen Bonas M, Dijksman T, Labuda L, et al. CD24(hi)CD27(+) B cells from patients with allergic asthma have impaired regulatory activity in response to lipopolysaccharide. Clin Exp Allergy. 2013 Apr;44:517-28.
    • (2013) Clin Exp Allergy , vol.44 , pp. 517-528
    • Van Der Vlugt, L.1    Mlejnek, E.2    Ozir-Fazalalikhan, A.3    Janssen Bonas, M.4    Dijksman, T.5    Labuda, L.6
  • 160
    • 84905051610 scopus 로고    scopus 로고
    • Regulatory B10 cells are decreased in patients with rheumatoid arthritis and are inversely correlated with disease activity
    • Daien CI, Gailhac S, Mura T, Audo R, Combe B, Hahne M, et al. Regulatory B10 cells are decreased in patients with rheumatoid arthritis and are inversely correlated with disease activity. Arthritis Rheum. 2014;66:2037-46.
    • (2014) Arthritis Rheum , vol.66 , pp. 2037-2046
    • Daien, C.I.1    Gailhac, S.2    Mura, T.3    Audo, R.4    Combe, B.5    Hahne, M.6
  • 161
    • 84896789725 scopus 로고    scopus 로고
    • IL10-producing B cells are induced early in HIV-1 infection andsuppress HIV-1-specific T cell responses
    • Jan
    • Liu J, Zhan W, Kim CJ, Clayton K, Zhao H, Lee E, et al. IL10-producing B cells are induced early in HIV-1 infection and suppress HIV-1-specific T cell responses. PLoS One. 2014 Jan;9:e89236.
    • (2014) Plos One , vol.9
    • Liu, J.1    Zhan, W.2    Kim, C.J.3    Clayton, K.4    Zhao, H.5    Lee, E.6
  • 163
    • 0032247323 scopus 로고    scopus 로고
    • The thyrotropin (TSH) receptor: Interaction with TSH and autoantibodies
    • Dec
    • Rapoport B, Chazenbalk G, Jaume J, McLachlan S. The thyrotropin (TSH) receptor: interaction with TSH and autoantibodies. Endocr Rev. 1998 Dec;19:673-716.
    • (1998) Endocr Rev , vol.19 , pp. 673-716
    • Rapoport, B.1    Chazenbalk, G.2    Jaume, J.3    McLachlan, S.4
  • 164
    • 0034718938 scopus 로고    scopus 로고
    • Graves’ disease͘
    • Weetman ͘A. Graves’ disease͘. N Engl J Med͘ 2000;343:1236-48.
    • (2000) N Engl J Med͘ , vol.343 , pp. 1236-1248
    • Weetman, A.1
  • 165
    • 18044390659 scopus 로고    scopus 로고
    • Immunogenetics of Hashimoto’s thyroiditis
    • Mar 11
    • Chistiakov D. Immunogenetics of Hashimoto’s thyroiditis. J Autoimmune Dis. 2005 Mar 11;2:1.
    • (2005) J Autoimmune Dis , vol.2 , pp. 1
    • Chistiakov, D.1
  • 166
    • 0029896946 scopus 로고    scopus 로고
    • Chronic Autoimmune Thyroiditis
    • Dayan C, Daniels G. Chronic Autoimmune Thyroiditis. N Engl J Med. 1996;335:99-107.
    • (1996) N Engl J Med , vol.335 , pp. 99-107
    • Dayan, C.1    Daniels, G.2
  • 167
    • 0035555276 scopus 로고    scopus 로고
    • Determinants of autoimmune thyroid disease
    • Weetman AP. Determinants of autoimmune thyroid disease. Nat Immunol. 2001 Sep;2:769-70.
    • (2001) Nat Immunol , vol.2 , pp. 769-770
    • Weetman, A.P.1
  • 169
    • 0034816710 scopus 로고    scopus 로고
    • Haemodynamic changes following treatment of subclinical and overthyperthyroidism
    • Oct 1
    • Faber J, Wiinberg N, Schifter S, Mehlsen J. Haemodynamic changes following treatment of subclinical and overt hyperthyroidism. Eur J Endocrinol. 2001 Oct 1;145:391-6.
    • (2001) Eur J Endocrinol , vol.145 , pp. 391-396
    • Faber, J.1    Wiinberg, N.2    Schifter, S.3    Mehlsen, J.4
  • 170
    • 84896319312 scopus 로고    scopus 로고
    • Hashimoto thyroiditis: Clinical and diagnostic criteria. Autoimmun
    • Caturegli P, De Remigis A, Rose N. Hashimoto thyroiditis: clinical and diagnostic criteria. Autoimmun Rev. Elsevier B.V.; 2014;13:391-7.
    • (2014) Rev. Elsevier B.V. , vol.13 , pp. 391-397
    • Caturegli, P.1    De Remigis, A.2    Rose, N.3
  • 171
    • 67349199596 scopus 로고    scopus 로고
    • The etiology of autoimmune thyroid disease: A story of genes and environment
    • Tomer Y, Huber A. The etiology of autoimmune thyroid disease: a story of genes and environment. J Autoimmun. 2009;32:231-9.
    • (2009) J Autoimmun , vol.32 , pp. 231-239
    • Tomer, Y.1    Huber, A.2
  • 172
    • 80052703117 scopus 로고    scopus 로고
    • The epidemiology of thyroid disease
    • Jan
    • Vanderpump MP. The epidemiology of thyroid disease. Br Med Bull. 2011 Jan;99:39-51.
    • (2011) Br Med Bull , vol.99 , pp. 39-51
    • Vanderpump, M.P.1
  • 173
    • 84857855590 scopus 로고    scopus 로고
    • Twin studies as a model for exploring the aetiology of autoimmune thyroid disease
    • Apr
    • Brix TH, Hegedüs L. Twin studies as a model for exploring the aetiology of autoimmune thyroid disease. Clin Endocrinol (Oxf). 2012 Apr;76:457-64.
    • (2012) Clin Endocrinol (Oxf) , vol.76 , pp. 457-464
    • Brix, T.H.1    Hegedüs, L.2
  • 174
    • 0034453053 scopus 로고    scopus 로고
    • A Population-Based Study of Chronic Autoimmune Hypothyroidism in Danish Twins
    • Brix TH, Kyvik KO, Hegedu L. A Population-Based Study of Chronic Autoimmune Hypothyroidism in Danish Twins. J Clin Endocrinol Metab. 2000;85:536-9.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 536-539
    • Brix, T.H.1    Kyvik, K.O.2    Hegedu, L.3
  • 176
    • 84902590036 scopus 로고    scopus 로고
    • Mechanisms in endocrinology: Autoimmune thyroid disease: Old and new players
    • Jun
    • Effraimidis G, Wiersinga WM. Mechanisms in endocrinology: autoimmune thyroid disease: old and new players. Eur J Endocrinol. 2014 Jun;170:R241-R252.
    • (2014) Eur J Endocrinol , vol.170 , pp. R241-R252
    • Effraimidis, G.1    Wiersinga, W.M.2
  • 177
    • 27744454481 scopus 로고    scopus 로고
    • High frequency of skewed X-chromosome inactivation in females with autoimmune thyroid disease: A possible explanation for the female predisposition to thyroid autoimmunity
    • Nov
    • Brix TH, Knudsen GPS, Kristiansen M, Kyvik KO, Orstavik KH, Hegedüs L. High frequency of skewed X-chromosome inactivation in females with autoimmune thyroid disease: a possible explanation for the female predisposition to thyroid autoimmunity. J Clin Endocrinol Metab. 2005 Nov;90:5949-53.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 5949-5953
    • Brix, T.H.1    Knudsen, G.2    Kristiansen, M.3    Kyvik, K.O.4    Orstavik, K.H.5    Hegedüs, L.6
  • 179
    • 0035095887 scopus 로고    scopus 로고
    • Evidence for a Major Role of Heredity in Graves’ Disease :Population-Based Study of Two Danish Twin Cohorts
    • Brix TH, Kyvik KO, Christensen K, Twin TD. Evidence for a Major Role of Heredity in Graves’ Disease : Population-Based Study of Two Danish Twin Cohorts. J Clin Endocrinol Metab. 2001;86:930-4.
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 930-934
    • Brix, T.H.1    Kyvik, K.O.2    Christensen, K.3    Twin, T.D.4
  • 180
    • 0037269502 scopus 로고    scopus 로고
    • Autoimmune thyroid disease: Propagation and progression
    • Weetman AP. Autoimmune thyroid disease: propagation and progression. Eur J Endocrinol. 2003;148:1-9.
    • (2003) Eur J Endocrinol , vol.148 , pp. 1-9
    • Weetman, A.P.1
  • 181
    • 84872069859 scopus 로고    scopus 로고
    • Fine mapping of loci linked to autoimmune thyroid disease identifies novel susceptibility genes
    • Jan
    • Tomer Y, Hasham A, Davies TF, Stefan M, Concepcion E, Keddache M, et al. Fine mapping of loci linked to autoimmune thyroid disease identifies novel susceptibility genes. J Clin Endocrinol Metab. 2013 Jan;98:E144-E152.
    • (2013) J Clin Endocrinol Metab , vol.98 , pp. E144-E152
    • Tomer, Y.1    Hasham, A.2    Davies, T.F.3    Stefan, M.4    Concepcion, E.5    Keddache, M.6
  • 182
    • 0036774549 scopus 로고    scopus 로고
    • Large differences in incidences of overthyperand hypothyroidism associated with a small differencein iodine intake: A prospective comparative register-basedpopulation survey
    • Oct
    • Bülow Pedersen I, Knudsen N, Jørgensen T, Perrild H, Ovesen L, Laurberg P. Large differences in incidences of overt hyperand hypothyroidism associated with a small difference in iodine intake: a prospective comparative register-based population survey. J Clin Endocrinol Metab. 2002 Oct;87:4462-9.
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 4462-4469
    • Bülow Pedersen, I.1    Knudsen, N.2    Jørgensen, T.3    Perrild, H.4    Ovesen, L.5    Laurberg, P.6
  • 183
    • 68949208812 scopus 로고    scopus 로고
    • Lower prevalence of mild hyperthyroidism related to a higher iodine intake in the population: Prospective study of a mandatory iodization programme
    • Sep
    • Vejbjerg P, Knudsen N, Perrild H, Laurberg P, Carlé A, Pedersen IB, et al. Lower prevalence of mild hyperthyroidism related to a higher iodine intake in the population: prospective study of a mandatory iodization programme. Clin Endocrinol (Oxf). 2009 Sep;71:440-5.
    • (2009) Clin Endocrinol (Oxf) , vol.71 , pp. 440-445
    • Vejbjerg, P.1    Knudsen, N.2    Perrild, H.3    Laurberg, P.4    Carlé, A.5    Pedersen, I.B.6
  • 184
    • 70349728782 scopus 로고    scopus 로고
    • More hypothyroidism and less hyperthyroidism with sufficient iodine nutrition compared to mild iodine deficiency--a comparative population-based study of older people
    • Oct 20
    • Andersen S, Iversen F, Terpling S, Pedersen KM, Gustenhoff P, Laurberg P. More hypothyroidism and less hyperthyroidism with sufficient iodine nutrition compared to mild iodine deficiency--a comparative population-based study of older people. Maturitas. 2009 Oct 20;64:126-31.
    • (2009) Maturitas , vol.64 , pp. 126-131
    • Andersen, S.1    Iversen, F.2    Terpling, S.3    Pedersen, K.M.4    Gustenhoff, P.5    Laurberg, P.6
  • 185
    • 34547822550 scopus 로고    scopus 로고
    • An increased incidence of overt hypothyroidism after iodine fortification of salt in Denmark: A prospective population study
    • Aug
    • Pedersen IB, Laurberg P, Knudsen N, Jørgensen T, Perrild H, Ovesen L, et al. An increased incidence of overt hypothyroidism after iodine fortification of salt in Denmark: a prospective population study. J Clin Endocrinol Metab. 2007 Aug;92:3122-7.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 3122-3127
    • Pedersen, I.B.1    Laurberg, P.2    Knudsen, N.3    Jørgensen, T.4    Perrild, H.5    Ovesen, L.6
  • 186
    • 0034643066 scopus 로고    scopus 로고
    • Cigarette Smoking and Risk of Clinically Overt Thyroid Disease
    • Brix TH, Hansen PS, Kyvik KO, Hegedüs L. Cigarette Smoking and Risk of Clinically Overt Thyroid Disease. Arch Intern Med. 2000;160:661-6.
    • (2000) Arch Intern Med , vol.160 , pp. 661-666
    • Brix, T.H.1    Hansen, P.S.2    Kyvik, K.O.3    Hegedüs, L.4
  • 187
    • 84891852676 scopus 로고    scopus 로고
    • Smoking reduces the risk of hypothyroidism and increases the risk of hyperthyroidism: Evidence from 450,842 mothers giving birth in Denmark
    • Feb
    • Andersen SL, Olsen J, Wu C Sen, Laurberg P. Smoking reduces the risk of hypothyroidism and increases the risk of hyperthyroidism: evidence from 450,842 mothers giving birth in Denmark. Clin Endocrinol (Oxf). 2014 Feb;80:307-14.
    • (2014) Clin Endocrinol (Oxf) , vol.80 , pp. 307-314
    • Andersen, S.L.1    Olsen, J.2    C Sen, W.3    Laurberg, P.4
  • 188
    • 2342584637 scopus 로고    scopus 로고
    • Relationship between cigarette smoking and Graves’ ophthalmopathy͘
    • Hegedüs L, Brix TH, Vestergaard P. Relationship between cigarette smoking and Graves’ ophthalmopathy͘. J Endocrinol Invest. 2004;27:265-71.
    • (2004) J Endocrinol Invest , vol.27 , pp. 65-71
    • Hegedüs, L.1    Brix, T.H.2    Vestergaard, P.3
  • 189
    • 84866664940 scopus 로고    scopus 로고
    • Moderate alcohol consumption may protect against overt autoimmune hypothyroidism: A populationbased case-control study
    • Oct
    • Carlé A, Pedersen IB, Knudsen N, Perrild H, Ovesen L, Rasmussen LB, et al. Moderate alcohol consumption may protect against overt autoimmune hypothyroidism: a populationbased case-control study. Eur J Endocrinol. 2012 Oct;167:483-90.
    • (2012) Eur J Endocrinol , vol.167 , pp. 483-490
    • Carlé, A.1    Pedersen, I.B.2    Knudsen, N.3    Perrild, H.4    Ovesen, L.5    Rasmussen, L.B.6
  • 191
    • 2942592216 scopus 로고    scopus 로고
    • Differences in thyroid-infiltrating B lymphocytes in patients with Graves’ disease: Relationship to autoantibody detection
    • May
    • Segundo C, Rodríguez C, Aguilar M, García-Poley A, Gavilán I, Bellas C, et al. Differences in thyroid-infiltrating B lymphocytes in patients with Graves’ disease: relationship to autoantibody detection. Thyroid. 2004 May;14:337-44.
    • (2004) Thyroid , vol.14 , pp. 337-344
    • Segundo, C.1    Rodríguez, C.2    Aguilar, M.3    García-Poley, A.4    Gavilán, I.5    Bellas, C.6
  • 192
    • 35948970565 scopus 로고    scopus 로고
    • The role of apoptosis in thyroid autoimmunity
    • Oct
    • Wang SH, Baker JR. The role of apoptosis in thyroid autoimmunity. Thyroid. 2007 Oct;17:975-9.
    • (2007) Thyroid , vol.17 , pp. 975-979
    • Wang, S.H.1    Baker, J.R.2
  • 193
    • 66449126331 scopus 로고    scopus 로고
    • Interaction of lymphocytes and thyrocytes in Graves’ disease and nonautoimmune thyroid diseases in immunohistochemical and ultrastructural investigations
    • Jan
    • Ben-Skowronek I, Sierocinska-Sawa J, Szewczyk L, Korobowicz E. Interaction of lymphocytes and thyrocytes in Graves’ disease and nonautoimmune thyroid diseases in immunohistochemical and ultrastructural investigations. Horm Res. 2009 Jan;71:350-8.
    • (2009) Horm Res , vol.71 , pp. 350-358
    • Ben-Skowronek, I.1    Sierocinska-Sawa, J.2    Szewczyk, L.3    Korobowicz, E.4
  • 194
    • 0034842962 scopus 로고    scopus 로고
    • Thyroid Autoimmune Disease: Demonstration of thyroid antigen-specific B cells and recombination-activating gene expression in chemokine-containing active intrathyroidal germinal centers
    • Armengol MP, Juan M, Lucas-Martin A, Jaraquemada D, Gallart T, Pujol-Borrell R. Thyroid Autoimmune Disease: Demonstration of thyroid antigen-specific B cells and recombination-activating gene expression in chemokine-containing active intrathyroidal germinal centers. Am J Pathol. 2001;159:861-73.
    • (2001) Am J Pathol , vol.159 , pp. 861-873
    • Armengol, M.P.1    Juan, M.2    Lucas-Martin, A.3    Jaraquemada, D.4    Gallart, T.5    Pujol-Borrell, R.6
  • 195
    • 72949104221 scopus 로고    scopus 로고
    • Dysregulation of germinal centres in autoimmune disease
    • Dec
    • Vinuesa CG, Sanz I, Cook MC. Dysregulation of germinal centres in autoimmune disease. Nat Rev Immunol. 2009 Dec;9:845-57.
    • (2009) Nat Rev Immunol , vol.9 , pp. 845-857
    • Vinuesa, C.G.1    Sanz, I.2    Cook, M.C.3
  • 197
    • 4544336634 scopus 로고    scopus 로고
    • Affinity-enrichment of thyrotropin receptor autoantibodies from Graves’ patients and normal individuals provides insight into their properties and possible origin from natural antibodies
    • Latrofa F, Chazenbalk GD, Pichurin P, Chen C-R, McLachlan SM, Rapoport B. Affinity-enrichment of thyrotropin receptor autoantibodies from Graves’ patients and normal individuals provides insight into their properties and possible origin from natural antibodies. J Clin Endocrinol Metab. 2004 Sep;89:4734-45.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 4734-4745
    • Latrofa, F.1    Chazenbalk, G.D.2    Pichurin, P.3    Chen, C.-R.4    McLachlan, S.M.5    Rapoport, B.6
  • 198
    • 47949112820 scopus 로고    scopus 로고
    • Techniques to quantify TSH receptor antibodies
    • Aug
    • Ajjan R, Weetman A. Techniques to quantify TSH receptor antibodies. Nat Clin Pract Endocrinol Metab. 2008 Aug;4:461-8.
    • (2008) Nat Clin Pract Endocrinol Metab , vol.4 , pp. 461-468
    • Ajjan, R.1    Weetman, A.2
  • 200
    • 84867839277 scopus 로고    scopus 로고
    • Davies TF. Delineating the autoimmune mechanisms in Graves’ disease͘
    • Dec
    • Morshed SA, Latif R, Davies TF. Delineating the autoimmune mechanisms in Graves’ disease͘. Immunol Res͘ 2012 Dec;54:191-203.
    • (2012) Immunol Res͘ , vol.54 , pp. 191-203
    • Morshed, S.A.1    Latif, R.2
  • 201
    • 35948944223 scopus 로고    scopus 로고
    • The thyrotropin receptor in Graves’ disease͘ Thyroid͘
    • Oct
    • Rapoport B, McLachlan SM. The thyrotropin receptor in Graves’ disease͘ Thyroid͘ 2007 Oct;17:911-22.
    • (2007) Thyroid? , vol.17 , pp. 911-922
    • Rapoport, B.1    McLachlan, S.M.2
  • 202
    • 62349107363 scopus 로고    scopus 로고
    • Evidence that shed thyrotropin receptor A subunits drive affinity maturation of autoantibodies causing Graves’ disease͘
    • Mar
    • Mizutori Y, Chen C-R, Latrofa F, McLachlan SM, Rapoport B. Evidence that shed thyrotropin receptor A subunits drive affinity maturation of autoantibodies causing Graves’ disease͘. J Clin Endocrinol Metab. 2009 Mar;94:927-35.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 927-935
    • Mizutori, Y.1    Chen, C.-R.2    Latrofa, F.3    McLachlan, S.M.4    Rapoport, B.5
  • 204
    • 2642699935 scopus 로고    scopus 로고
    • Single-cell analysis of intrathyroidallymphocytes shows differential cytokine expression in Hashimoto’ s and Graves’ disease͘
    • Roura-Mir C, Catalfamo M, Sospedra M, Alcalde L, PujolBorrell R, Jaraquemada D. Single-cell analysis of intrathyroidal lymphocytes shows differential cytokine expression in Hashimoto’ s and Graves’ disease͘. Eur J Immunol͘ 1997;27:3290-302.
    • (1997) Eur J Immunol͘ , vol.27 , pp. 3290-3302
    • Roura-Mir, C.1    Catalfamo, M.2    Sospedra, M.3    Alcalde, L.4    Pujolborrell, R.5    Jaraquemada, D.6
  • 205
    • 0029923832 scopus 로고    scopus 로고
    • Different Cytokine mRNProfiles in Graves’ Disease, Hashimoto'sThyroiditis, and Nonautoimmune Thyroid Disorders Determined by Quantitative Reverse Transcriptase PolymeraseChain Reaction (RT-PCR)
    • Apr
    • Heuer M, Aust G, Ode-Hakim S, Scherbaum WA. Different Cytokine mRN Profiles in Graves’ Disease, Hashimoto's Thyroiditis, and Nonautoimmune Thyroid Disorders Determined by Quantitative Reverse Transcriptase Polymerase Chain Reaction (RT-PCR). Thyroid. 1996 Apr;6:97-106.
    • (1996) Thyroid , vol.6 , pp. 97-106
    • Heuer, M.1    Aust, G.2    Ode-Hakim, S.3    Scherbaum, W.A.4
  • 206
    • 0347264749 scopus 로고    scopus 로고
    • Prevention of Autoantibody-Mediated Graves’-Like Hyperthyroidism in Mice with IL-4, a Th2 Cytokine
    • Apr 1
    • Nagayama Y, Mizuguchi H, Hayakawa T, Niwa M, McLachlan S, Rapoport B. Prevention of Autoantibody-Mediated Graves’-Like Hyperthyroidism in Mice with IL-4, a Th2 Cytokine. J Immunol. 2003 Apr 1;170:3522-7.
    • (2003) J Immunol , vol.170 , pp. 3522-3527
    • Nagayama, Y.1    Mizuguchi, H.2    Hayakawa, T.3    Niwa, M.4    McLachlan, S.5    Rapoport, B.6
  • 207
    • 0025763807 scopus 로고
    • IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells
    • May 15
    • Fiorentino D, Zlotnik A, Vieira P, Mosmann T, Howard M, Moore K, et al. IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells. J Immunol. 1991 May 15;146:3444-51.
    • (1991) J Immunol , vol.146 , pp. 3444-3451
    • Fiorentino, D.1    Zlotnik, A.2    Vieira, P.3    Mosmann, T.4    Howard, M.5    Moore, K.6
  • 208
    • 0028116618 scopus 로고
    • Cytokine-induced immune deviation as a therapy for Inflammatory Autoimmune Disease
    • Racke MK, Bonomo A, Scott DE, Cannella B, Levine A, Raine CS, et al. Cytokine-induced immune deviation as a therapy for Inflammatory Autoimmune Disease. J Exp Med. 1994;180:1961-6.
    • (1994) J Exp Med , vol.180 , pp. 1961-1966
    • Racke, M.K.1    Bonomo, A.2    Scott, D.E.3    Cannella, B.4    Levine, A.5    Raine, C.S.6
  • 209
    • 5944261448 scopus 로고    scopus 로고
    • Control of target cell survival in thyroid autoimmunity by T helper cytokines via regulation of apoptotic proteins
    • Dec
    • Stassi G, Di Liberto D, Todaro M, Zeuner A, Ricci-Vitiani L, Stoppacciaro A, et al. Control of target cell survival in thyroid autoimmunity by T helper cytokines via regulation of apoptotic proteins. Nat Immunol. 2000 Dec;1:483-8.
    • (2000) Nat Immunol , vol.1 , pp. 483-488
    • Stassi, G.1    Di Liberto, D.2    Todaro, M.3    Zeuner, A.4    Ricci-Vitiani, L.5    Stoppacciaro, A.6
  • 210
    • 0028579773 scopus 로고
    • Autoimmune thyroid disease: Further developments in our understanding
    • Dec
    • Weetman A, McGregor A. Autoimmune thyroid disease: further developments in our understanding. Endocr Rev. 1994 Dec;15:788-830.
    • (1994) Endocr Rev , vol.15 , pp. 788-830
    • Weetman, A.1    McGregor, A.2
  • 211
    • 45449099469 scopus 로고    scopus 로고
    • Cytokine-producing B lymphocytes—key regulators of immunity
    • Lund FE. Cytokine-producing B lymphocytes—key regulators of immunity. Curr Opin Immunol. 2008;20:332-8.
    • (2008) Curr Opin Immunol , vol.20 , pp. 332-338
    • Lund, F.E.1
  • 212
    • 84922407586 scopus 로고    scopus 로고
    • The immune potential and immunopathology of cytokine-producing B cell subsets: A comprehensive review
    • Apr 30
    • Bao Y, Cao X. The immune potential and immunopathology of cytokine-producing B cell subsets: A comprehensive review. J Autoimmun. Elsevier Ltd; 2014 Apr 30;10.1016.
    • (2014) J Autoimmun. Elsevier Ltd , vol.10 , pp. 1016
    • Bao, Y.1    Cao, X.2
  • 213
    • 0030872479 scopus 로고    scopus 로고
    • Analysis of apoptosis in relation to tissue destruction associated with Hashimoto’s autoimmune thyroiditis͘
    • Hammond L, Lowdell M, Cerrano P, Goode A, Bottazzo G, Mirakian R. Analysis of apoptosis in relation to tissue destruction associated with Hashimoto’s autoimmune thyroiditis͘ J Pathol. 1997;182:138-44.
    • (1997) J Pathol , vol.182 , pp. 38-44
    • Hammond, L.1    Lowdell, M.2    Cerrano, P.3    Goode, A.4    Bottazzo, G.5    Mirakian, R.6
  • 214
    • 0024460344 scopus 로고
    • Depletion of L3T4+ and Lyt-2+ cells by rat monoclonal antibodies alters the development of adoptively transferred experimental autoimmune thyroiditis
    • Sep
    • Flynn J, Conaway D, Cobbold S, Waldmann H, Kong Y. Depletion of L3T4+ and Lyt-2+ cells by rat monoclonal antibodies alters the development of adoptively transferred experimental autoimmune thyroiditis. Cell Immunol. 1989 Sep;122:377-90.
    • (1989) Cell Immunol , vol.122 , pp. 377-390
    • Flynn, J.1    Conaway, D.2    Cobbold, S.3    Waldmann, H.4    Kong, Y.5
  • 216
    • 0025905925 scopus 로고
    • Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes
    • May 1
    • Peters P, Borst J, Oorschot V, Fukuda M, Krähenbühl O, Tschopp J, et al. Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes. J Exp Med. 1991 May 1;173:1099-109.
    • (1991) J Exp Med , vol.173 , pp. 1099-1109
    • Peters, P.1    Borst, J.2    Oorschot, V.3    Fukuda, M.4    Krähenbühl, O.5    Tschopp, J.6
  • 218
    • 0028114746 scopus 로고
    • Perforin expression by thyroid-infiltrating T cells in autoimmune thyroid disease
    • Dec
    • Wu Z, Podack E, McKenzie J, Olsen K, Zakarija M. Perforin expression by thyroid-infiltrating T cells in autoimmune thyroid disease. Clin Exp Immunol. 1994 Dec;98:470-7.
    • (1994) Clin Exp Immunol , vol.98 , pp. 470-477
    • Wu, Z.1    Podack, E.2    McKenzie, J.3    Olsen, K.4    Zakarija, M.5
  • 219
    • 84859540261 scopus 로고    scopus 로고
    • Evidence of a combined cytotoxic thyroglobulin and thyroperoxidase epitope-specific cellular immunity in Hashimoto’s thyroiditis͘
    • Apr
    • Ehlers M, Thiel A, Bernecker C, Porwol D, Papewalis C, Willenberg HS, et al. Evidence of a combined cytotoxic thyroglobulin and thyroperoxidase epitope-specific cellular immunity in Hashimoto’s thyroiditis͘ J Clin Endocrinol Metab͘ 2012 Apr;97:1347-54.
    • (2012) J Clin Endocrinol Metab͘ , vol.97 , pp. 1347-1354
    • Ehlers, M.1    Thiel, A.2    Bernecker, C.3    Porwol, D.4    Papewalis, C.5    Willenberg, H.S.6
  • 220
    • 0032575714 scopus 로고    scopus 로고
    • Death receptors: Signaling and modulation
    • Aug 28
    • Ashkenazi A, Dixit V. Death receptors: signaling and modulation. Science. 1998 Aug 28;281:1305-8.
    • (1998) Science , vol.281 , pp. 1305-1308
    • Ashkenazi, A.1    Dixit, V.2
  • 221
    • 0031034933 scopus 로고    scopus 로고
    • Potential Involvement of Fas and its ligand in the pathogenesis of Hashimoto’s thyroiditis͘
    • Giordano C, Stassi G, De Maria R, Todaro M, Richiusa P, Papoff G, et al. Potential Involvement of Fas and its ligand in the pathogenesis of Hashimoto’s thyroiditis͘ Science͘ 1997;275:960-4.
    • (1997) Science͘ , vol.275 , pp. 960-964
    • Giordano, C.1    Stassi, G.2    De Maria, R.3    Todaro, M.4    Richiusa, P.5    Papoff, G.6
  • 222
    • 0031790839 scopus 로고    scopus 로고
    • Fas/Fas ligand up-regulation and Bcl-2 down-regulation may be significant in the pathogenesis of Hashimoto’s thyroiditis͘
    • Mitsiades N, Poulaki V, Kotoula V, Mastorakos G, Tseleni-balafouta S, Koutras D, et al. Fas/Fas ligand up-regulation and Bcl-2 down-regulation may be significant in the pathogenesis of Hashimoto’s thyroiditis͘ J Clin Endocrinol Metab͘ 1998;83:2199-203.
    • (1998) J Clin Endocrinol Metab͘ , vol.83 , pp. 2199-2203
    • Mitsiades, N.1    Poulaki, V.2    Kotoula, V.3    Mastorakos, G.4    Tseleni-Balafouta, S.5    Koutras, D.6
  • 223
    • 0032821034 scopus 로고    scopus 로고
    • The Role of Fas-mediated apoptosis in Thyroid Autoimmune disease
    • Borgerson K, Bretz J, Baker J. The Role of Fas-mediated apoptosis in Thyroid Autoimmune disease. Autoimmunity. 1999;30:251-64.
    • (1999) Autoimmunity , vol.30 , pp. 251-264
    • Borgerson, K.1    Bretz, J.2    Baker, J.3
  • 224
    • 0031901457 scopus 로고    scopus 로고
    • Fas-FasL interactions: A common pathogenetic mechanism in organ-specific autoimmunity
    • Mar
    • De Maria R, Testi R. Fas-FasL interactions: a common pathogenetic mechanism in organ-specific autoimmunity. Immunol Today. 1998 Mar;19:121-5.
    • (1998) Immunol Today , vol.19 , pp. 121-125
    • De Maria, R.1    Testi, R.2
  • 225
  • 226
    • 0032907268 scopus 로고    scopus 로고
    • Fas/Fas Ligand-Driven T Cell Apoptosis as a Consequence of Ineffective Thyroid Immunoprivilege in Hashimoto’s Thyroiditis͘
    • Stassi G, Todaro M, Bucchieri F, Farina F, Zummo G, Maria R De, et al. Fas/Fas Ligand-Driven T Cell Apoptosis as a Consequence of Ineffective Thyroid Immunoprivilege in Hashimoto’s Thyroiditis͘ J Immunol͘ 1999;162:263-7.
    • (1999) J Immunol͘ , vol.162 , pp. 263-267
    • Stassi, G.1    Todaro, M.2    Bucchieri, F.3    Farina, F.4    Zummo, G.5    De, M.R.6
  • 227
    • 0021211312 scopus 로고
    • Antibody-Dependent Cell Mediated Cytotoxicity against Human Thyroid Cells in Hashimoto’s Thyroiditis but Not Graves' Disease͘
    • Bogner U, Schleusener H, Wall J. Antibody-Dependent Cell Mediated Cytotoxicity against Human Thyroid Cells in Hashimoto’s Thyroiditis but Not Graves' Disease͘ J Clin Endocrinol Metab. 1984;59:734-8.
    • (1984) J Clin Endocrinol Metab , vol.59 , pp. 734-738
    • Bogner, U.1    Schleusener, H.2    Wall, J.3
  • 228
    • 0031029105 scopus 로고    scopus 로고
    • Recombinant Thyroid Peroxidase-Specific Fab Converted to Immunoglobulin G (IgG) Molecules : Evidence for Thyroid Cell Damage by IgG1, but Not IgG4, Autoantibodies
    • Guo J, Jaume JC, Rapoport B, McLachlan SM. Recombinant Thyroid Peroxidase-Specific Fab Converted to Immunoglobulin G (IgG) Molecules : Evidence for Thyroid Cell Damage by IgG1, but Not IgG4, Autoantibodies. J Clin Endocrinol Metab. 1997;82:925-31.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 925-931
    • Guo, J.1    Jaume, J.C.2    Rapoport, B.3    McLachlan, S.M.4
  • 229
    • 0025114227 scopus 로고
    • Regulation of interleukin-6 release by human thyrocytes
    • Nov
    • Weetman A, Bright-Thomas R, Freeman M. Regulation of interleukin-6 release by human thyrocytes. J Endocrinol. 1990 Nov;127:357-61.
    • (1990) J Endocrinol , vol.127 , pp. 357-361
    • Weetman, A.1    Bright-Thomas, R.2    Freeman, M.3
  • 231
    • 70349968091 scopus 로고    scopus 로고
    • Role for autoantibodies in enhancement of pro-inflammatory cytokine responses to a self-antigen, thyroid peroxidase. Clin Immunol
    • Nov
    • Nielsen CH, Brix TH, Leslie RGQ, Hegedüs L. A role for autoantibodies in enhancement of pro-inflammatory cytokine responses to a self-antigen, thyroid peroxidase. Clin Immunol. Elsevier Inc.; 2009 Nov;133:218-27.
    • (2009) Elsevier Inc. , vol.133 , pp. 218-227
    • Nielsen, C.H.1    Brix, T.H.2    Leslie, R.3    Hegedüs, L.A.4
  • 232
    • 0031024366 scopus 로고    scopus 로고
    • Anti-thyroglobulin Autoantibodies in Autoimmune Thyroid Diseases : Cross-Reactive or Pathogenic ?
    • Tomer Y. Anti-thyroglobulin Autoantibodies in Autoimmune Thyroid Diseases : Cross-Reactive or Pathogenic ? Clin Immunol Immunopathol. 1997;82:3-11.
    • (1997) Clin Immunol Immunopathol , vol.82 , pp. 3-11
    • Tomer, Y.1
  • 233
    • 0023637828 scopus 로고
    • Enhanced production of y-interferon by thyroidderived T cell clones from patients with Hashimoto’ s thyroiditis
    • Del Prete G, Tiri A, Mariottit S, Pincherat A, Ricci M, Cattedra R, et al. Enhanced production of y-interferon by thyroidderived T cell clones from patients with Hashimoto’ s thyroiditis. Clin Exp Immunol. 1987;69:323-31.
    • (1987) Clin Exp Immunol , vol.69 , pp. 323-331
    • Del Prete, G.1    Tiri, A.2    Mariottit, S.3    Pincherat, A.4    Ricci, M.5    Cattedra, R.6
  • 234
    • 0029843836 scopus 로고    scopus 로고
    • Intrathyroidal cytokine gene expression in Hashimoto’s thyroiditis
    • Sep
    • Ajjan R, Watson P, Mcintosh R, Weetman A. Intrathyroidal cytokine gene expression in Hashimoto’s thyroiditis. Clin Exp Immunol. 1996 Sep;105:523-8.
    • (1996) Clin Exp Immunol , vol.105 , pp. 523-528
    • Ajjan, R.1    Watson, P.2    McIntosh, R.3    Weetman, A.4
  • 235
    • 0032987199 scopus 로고    scopus 로고
    • Balance of Th1/Th2 cytokines in thyroid autoantibody synthesis in vitro
    • Jan
    • Guo J, Rapoport B, McLachlan S. Balance of Th1/Th2 cytokines in thyroid autoantibody synthesis in vitro. Autoimmunity. 1999 Jan;30:1-9.
    • (1999) Autoimmunity , vol.30 , pp. 1-9
    • Guo, J.1    Rapoport, B.2    McLachlan, S.3
  • 236
    • 4444325343 scopus 로고    scopus 로고
    • Unctional lymphocyte subset assessment of the Th1/Th2 profile inpatients with autoimmune thyroiditis by flowcytometric analysis of peripheral lymphocytes
    • Colin I, Isaac J, Dupret P, Ledant T, D’Hautcourt J͘ Functional lymphocyte subset assessment of the Th1/Th2 profile in patients with autoimmune thyroiditis by flowcytometric analysis of peripheral lymphocytes. J Biol Regul Homeost Agents. 2004;18:72-6.
    • (2004) J Biol Regul Homeost Agents. , vol.18 , pp. 72-76
    • Colin, I.1    Isaac, J.2    Dupret, P.3    Ledant, T.4    D’Hautcourt, J.͘.5
  • 237
    • 0028586699 scopus 로고
    • The potential immunological role of the thyroid cell in autoimmune thyroid disease
    • Weetman A. The potential immunological role of the thyroid cell in autoimmune thyroid disease. Thyroid. 1994;4:493-9.
    • (1994) Thyroid , vol.4 , pp. 493-499
    • Weetman, A.1
  • 239
    • 0031573671 scopus 로고    scopus 로고
    • Antigen Presentation by EpithelialCells Induces Anergic Immunoregulatory CD45RO+ T cells andDeletion of CD45RA+ T cells
    • Marelliberg FM, Weetman A, Frasca L, Deacock SJ, Imami N, Lombardi G, et al. Antigen Presentation by Epithelial Cells Induces Anergic Immunoregulatory CD45RO+ T cells and Deletion of CD45RA+ T cells. J Immunol. 1997;159:5853-61.
    • (1997) J Immunol , vol.159 , pp. 5853-5861
    • Marelliberg, F.M.1    Weetman, A.2    Frasca, L.3    Deacock, S.J.4    Imami, N.5    Lombardi, G.6
  • 240
    • 0031022641 scopus 로고    scopus 로고
    • Ribonucleic Acid in the Thyroid of Patients with Autoimmune Thyroid Disease *
    • Ajjan R, Watson P, Weetman A. Ribonucleic Acid in the Thyroid of Patients with Autoimmune Thyroid Disease *. J Clin Endocrinol Metab. 1997;82:666-9.
    • (1997) J Clin Endocrinol Metab , vol.82 , pp. 666-669
    • Ajjan, R.1    Watson, P.2    Weetman, A.3
  • 242
    • 0024408824 scopus 로고
    • TWO TYPES OFMOUSE T HELPER CELL IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
    • Fiorentino D, Bond M, Mosmann T. TWO TYPES OF MOUSE T HELPER CELL IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med. 1989;170:2081-95.
    • (1989) J Exp Med , vol.170 , pp. 2081-2095
    • Fiorentino, D.1    Bond, M.2    Mosmann, T.3
  • 243
    • 0026094306 scopus 로고
    • Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes
    • De Waal Malefyt R, Abrams J, Bennett B, Figdor CG, de Vries JE. Interleukin 10 (IL-10) inhibits cytokine synthesis by human monocytes: An autoregulatory role of IL-10 produced by monocytes. J Exp Med. 1991;174:1209-20.
    • (1991) J Exp Med , vol.174 , pp. 1209-1220
    • De Waal Malefyt, R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    De Vries, J.E.5
  • 244
    • 0024328679 scopus 로고
    • Mechanisms of T cell activation by the calcium ionophore ionomycin
    • Aug 15
    • Chatila T, Silverman L, Miller R, Geha R. Mechanisms of T cell activation by the calcium ionophore ionomycin. J Immunol. 1989 Aug 15;143:1283-9.
    • (1989) J Immunol , vol.143 , pp. 1283-1289
    • Chatila, T.1    Silverman, L.2    Miller, R.3    Geha, R.4
  • 246
    • 13844271381 scopus 로고    scopus 로고
    • Phorbol ester phorbol-12-myristate-13acetate promotes anchorage-independent growth and survival of melanomas through MEK-independent activation ofERK1/2
    • Apr 1
    • Jørgensen K, Skrede M, Cruciani V, Mikalsen S-O, Slipicevic A, Flørenes VA. Phorbol ester phorbol-12-myristate-13acetate promotes anchorage-independent growth and survival of melanomas through MEK-independent activation of ERK1/2. Biochem Biophys Res Commun. 2005 Apr 1;329:266-74.
    • (2005) Biochem Biophys Res Commun , vol.329 , pp. 266-274
    • Jørgensen, K.1    Skrede, M.2    Cruciani, V.3    Mikalsen, S.-O.4    Slipicevic, A.5    Flørenes, V.A.6
  • 247
    • 0034680145 scopus 로고    scopus 로고
    • Toll-like receptors in the induction of the innate immune response
    • Aderem A, Ulevitch RJ. Toll-like receptors in the induction of the innate immune response. Nature. 2000;406:782-7.
    • (2000) Nature , vol.406 , pp. 782-787
    • Aderem, A.1    Ulevitch, R.J.2
  • 248
    • 43549099277 scopus 로고    scopus 로고
    • Detection andisolation of cytokine secreting cells using the cytometric cytokine secretion assay
    • Feb;Chapter6:Unit 6.27
    • Assenmacher M, Löhning M, Radbruch A. Detection and isolation of cytokine secreting cells using the cytometric cytokine secretion assay. Curr Protoc Immunol. 2002 Feb;Chapter 6:Unit 6.27.
    • (2002) Curr Protoc Immunol
    • Assenmacher, M.1    Löhning, M.2    Radbruch, A.3
  • 249
    • 0028301797 scopus 로고
    • Brefeldin A causes structural and functional alterations of the trans-Golgi network of MDCK cells
    • Apr
    • Wagner M, Rajasekaran A, Hanzel D, Mayor S, RodriguezBoulan E. Brefeldin A causes structural and functional alterations of the trans-Golgi network of MDCK cells. J Cell Sci. 1994 Apr;107:933-43.
    • (1994) J Cell Sci , vol.107 , pp. 933-943
    • Wagner, M.1    Rajasekaran, A.2    Hanzel, D.3    Mayor, S.4    Rodriguezboulan, E.5
  • 250
    • 0024237306 scopus 로고
    • Brefeldin A Causes Disassembly of the Golgi Complex and Accumulation of Secretory Proteins in the Endoplasmic Reticulum
    • Fujiwara T, Yokotas S, Takatsukig A, Ikeharan Y. Brefeldin A Causes Disassembly of the Golgi Complex and Accumulation of Secretory Proteins in the Endoplasmic Reticulum. J Biol Chem. 1988;263:18545-52.
    • (1988) J Biol Chem , vol.263 , pp. 18545-18552
    • Fujiwara, T.1    Yokotas, S.2    Takatsukig, A.3    Ikeharan, Y.4
  • 251
    • 0025303531 scopus 로고
    • Inhibition by brefeldin A of presentation of exogenous protein antigens to MHC class II-restricted T cells
    • Adorini L, Ullrich S, Appella E, Fuchs S. Inhibition by brefeldin A of presentation of exogenous protein antigens to MHC class II-restricted T cells. Nature. 1990;346:63-6.
    • (1990) Nature , vol.346 , pp. 63-66
    • Adorini, L.1    Ullrich, S.2    Appella, E.3    Fuchs, S.4
  • 252
    • 0024338401 scopus 로고
    • Brefeldin A specifically inhibits presentation of protein antigens to cytotoxic T lymphocytes
    • Jun 2
    • Yewdell J, Bennink J. Brefeldin A specifically inhibits presentation of protein antigens to cytotoxic T lymphocytes. Science. 1989 Jun 2;244:1072-5.
    • (1989) Science , vol.244 , pp. 1072-1075
    • Yewdell, J.1    Bennink, J.2
  • 254
    • 0033120081 scopus 로고    scopus 로고
    • Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: Evidence for TLR4 as the Lps gene product
    • Apr1
    • Hoshino K, Takeuchi O, Kawai T, Sanjo H, Ogawa T, Takeda Y, et al. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the Lps gene product. J Immunol. 1999 Apr 1;162:3749-52.
    • (1999) J Immunol , vol.162 , pp. 3749-3752
    • Hoshino, K.1    Takeuchi, O.2    Kawai, T.3    Sanjo, H.4    Ogawa, T.5    Takeda, Y.6
  • 255
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Nov
    • Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol. 2001 Nov;1:135-45.
    • (2001) Nat Rev Immunol , vol.1 , pp. 135-145
    • Medzhitov, R.1
  • 256
    • 0037378954 scopus 로고    scopus 로고
    • Involvement of protein tyrosine kinase in Toll-like receptor 4mediated NF-kappa B activation in human peripheral blood monocytes
    • Apr
    • Chen L-Y, Zuraw BL, Zhao M, Liu F-T, Huang S, Pan ZK. Involvement of protein tyrosine kinase in Toll-like receptor 4mediated NF-kappa B activation in human peripheral blood monocytes. Am J Physiol Lung Cell Mol Physiol. 2003 Apr;284:L607-L613.
    • (2003) Am J Physiol Lung Cell Mol Physiol , vol.284 , pp. L607-L613
    • Chen, L.-Y.1    Zuraw, B.L.2    Zhao, M.3    Liu, F.-T.4    Huang, S.5    Pan, Z.K.6
  • 257
    • 0031726586 scopus 로고    scopus 로고
    • Sequential generation of cytokines during the initiative phase of inflammation, with reference to neutrophils
    • Oct
    • Matsukawa A, Yoshinaga M. Sequential generation of cytokines during the initiative phase of inflammation, with reference to neutrophils. Inflamm Res. 1998 Oct;47:S137-S144.
    • (1998) Inflamm Res , vol.47 , pp. S137-S144
    • Matsukawa, A.1    Yoshinaga, M.2
  • 258
    • 70350367856 scopus 로고    scopus 로고
    • Lipopolysaccharide-driven Th2 cytokine production in macrophages is regulated by both MyD88 and TRAM
    • Oct 23
    • Mukherjee S, Chen L-Y, Papadimos TJ, Huang S, Zuraw BL, Pan ZK. Lipopolysaccharide-driven Th2 cytokine production in macrophages is regulated by both MyD88 and TRAM. J Biol Chem. 2009 Oct 23;284:29391-8.
    • (2009) J Biol Chem , vol.284 , pp. 29391-29398
    • Mukherjee, S.1    Chen, L.-Y.2    Papadimos, T.J.3    Huang, S.4    Zuraw, B.L.5    Pan, Z.K.6
  • 259
    • 0037083341 scopus 로고    scopus 로고
    • Lipopolysaccharide Induces Rapid Production of IL-10 by Monocytes in the Presence of Apoptotic Neutrophils
    • Feb 15
    • Byrne A, Reen D. Lipopolysaccharide Induces Rapid Production of IL-10 by Monocytes in the Presence of Apoptotic Neutrophils. J Immunol. 2002 Feb 15;168:1968-77.
    • (2002) J Immunol , vol.168 , pp. 1968-1977
    • Byrne, A.1    Reen, D.2
  • 260
    • 73949121456 scopus 로고    scopus 로고
    • The self-antigen, thyroglobulin, induces antigen-experienced CD4+T cells from healthy donors to proliferate and promote production of the regulatory cytokine, interleukin-10, by monocytes
    • Nielsen CH, Galdiers MP, Hedegaard CJ, Leslie RGQ. The self-antigen, thyroglobulin, induces antigen-experienced CD4+T cells from healthy donors to proliferate and promote production of the regulatory cytokine, interleukin-10, by monocytes. Immunology. 2009;129:291-9.
    • (2009) Immunology , vol.129 , pp. 291-299
    • Nielsen, C.H.1    Galdiers, M.P.2    Hedegaard, C.J.3    Leslie, R.G.Q.4
  • 261
    • 0036570169 scopus 로고    scopus 로고
    • Quantitative Expression of Toll-Like Receptor 1-10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides
    • May 1
    • Hornung V, Rothenfusser S, Britsch S, Krug A, Jahrsdorfer B, Giese T, et al. Quantitative Expression of Toll-Like Receptor 1-10 mRNA in Cellular Subsets of Human Peripheral Blood Mononuclear Cells and Sensitivity to CpG Oligodeoxynucleotides. J Immunol. 2002 May 1;168:4531-7.
    • (2002) J Immunol , vol.168 , pp. 4531-4537
    • Hornung, V.1    Rothenfusser, S.2    Britsch, S.3    Krug, A.4    Jahrsdorfer, B.5    Giese, T.6
  • 262
    • 0041743207 scopus 로고    scopus 로고
    • The toll-like receptor repertoire of human B lymphocytes : Inducible and selective expression of TLR9 and TLR10 in normal and transformed cells
    • Bourke E, Bosisio D, Golay J, Polentarutti N, Mantovani A. The toll-like receptor repertoire of human B lymphocytes : inducible and selective expression of TLR9 and TLR10 in normal and transformed cells. Blood. 2003;102:956-63.
    • (2003) Blood , vol.102 , pp. 956-963
    • Bourke, E.1    Bosisio, D.2    Golay, J.3    Polentarutti, N.4    Mantovani, A.5
  • 264
    • 65249083921 scopus 로고    scopus 로고
    • B cells from periodontal disease patients expresssurface Toll-like receptor 4
    • Apr
    • Shin H, Zhang Y, Jagannathan M, Hasturk H, Kantarci A, Liu H, et al. B cells from periodontal disease patients express surface Toll-like receptor 4. J Leukoc Biol. 2009 Apr;85:648-55.
    • (2009) J Leukoc Biol , vol.85 , pp. 648-655
    • Shin, H.1    Zhang, Y.2    Jagannathan, M.3    Hasturk, H.4    Kantarci, A.5    Liu, H.6
  • 265
  • 266
    • 0036533202 scopus 로고    scopus 로고
    • Toll-like receptor 4 surface expression on human monocytes and B cells is modulated by IL-2 and IL-4
    • Apr 1
    • Mita Y, Dobashi K, Endou K, Kawata T, Shimizu Y, Nakazawa T, et al. Toll-like receptor 4 surface expression on human monocytes and B cells is modulated by IL-2 and IL-4. Immunol Lett. 2002 Apr 1;81:71-5.
    • (2002) Immunol Lett , vol.81 , pp. 71-75
    • Mita, Y.1    Dobashi, K.2    Endou, K.3    Kawata, T.4    Shimizu, Y.5    Nakazawa, T.6
  • 268
    • 73349120965 scopus 로고    scopus 로고
    • TLR cross-talk specifically regulates cytokine production by B cells from chronic inflammatory disease patients
    • Dec 1
    • Jagannathan M, Hasturk H, Liang Y, Shin H, Hetzel JT, Kantarci A, et al. TLR cross-talk specifically regulates cytokine production by B cells from chronic inflammatory disease patients. J Immunol. 2009 Dec 1;183:7461-70.
    • (2009) J Immunol , vol.183 , pp. 7461-7470
    • Jagannathan, M.1    Hasturk, H.2    Liang, Y.3    Shin, H.4    Hetzel, J.T.5    Kantarci, A.6
  • 269
    • 77957145333 scopus 로고    scopus 로고
    • What are regulatory B cells?
    • Oct
    • Gray D, Gray M. What are regulatory B cells? Eur J Immunol. 2010 Oct;40:2677-9.
    • (2010) Eur J Immunol , vol.40 , pp. 2677-2679
    • Gray, D.1    Gray, M.2
  • 270
    • 49249136452 scopus 로고    scopus 로고
    • Regulatory B cells as inhibitors of immune responses and inflammation
    • Aug
    • Bouaziz J-D, Yanaba K, Tedder TF. Regulatory B cells as inhibitors of immune responses and inflammation. Immunol Rev. 2008 Aug;224:201-14.
    • (2008) Immunol Rev , vol.224 , pp. 201-214
    • Bouaziz, J.-D.1    Yanaba, K.2    Tedder, T.F.3
  • 271
    • 0038142387 scopus 로고    scopus 로고
    • A role for Tolllike receptors in acquired immunity: Up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells
    • Jun 1
    • Bernasconi NL, Onai N, Lanzavecchia A. A role for Tolllike receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells. Blood. 2003 Jun 1;101:4500-4.
    • (2003) Blood , vol.101 , pp. 4500-4504
    • Bernasconi, N.L.1    Onai, N.2    Lanzavecchia, A.3
  • 272
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors : Critical proteins linking innate and acquired immunity
    • Akira S, Takeda K, Kaisho T. Toll-like receptors : critical proteins linking innate and acquired immunity. Nat Immunol. 2001;2:675-80.
    • (2001) Nat Immunol , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 273
    • 84857025735 scopus 로고    scopus 로고
    • Multiple mechanisms of immunesuppression by B lymphocytes
    • Jan
    • Klinker MW, Lundy SK. Multiple mechanisms of immune suppression by B lymphocytes. Mol Med. 2012 Jan;18:123-37.
    • (2012) Mol Med , vol.18 , pp. 123-137
    • Klinker, M.W.1    Lundy, S.K.2
  • 274
    • 79960145627 scopus 로고    scopus 로고
    • Regulatory B cells and allergic diseases
    • Jul
    • Noh G, Lee JH. Regulatory B cells and allergic diseases. Allergy Asthma Immunol Res. 2011 Jul;3:168-77.
    • (2011) Allergy Asthma Immunol Res , vol.3 , pp. 168-177
    • Noh, G.1    Lee, J.H.2
  • 276
    • 0024374764 scopus 로고
    • PROBING THE HUMAN B-CELL REPERTOIRE WITH EBV : Polyreactiventibodies and CD5+ B Lymphocytes
    • Casali P, Notkins AL. PROBING THE HUMAN B-CELL REPERTOIRE WITH EBV : Polyreactive ntibodies and CD5+ B Lymphocytes. Annu Rev Immunol. 1989;7:513-35.
    • (1989) Annu Rev Immunol , vol.7 , pp. 513-535
    • Casali, P.1    Notkins, A.L.2
  • 277
    • 84873673878 scopus 로고    scopus 로고
    • Natural autoantibodies and associated B cells in immunity and autoimmunity
    • Mannoor K, Xu Y, Chen C. Natural autoantibodies and associated B cells in immunity and autoimmunity. Autoimmunity. 2013;46:138-47.
    • (2013) Autoimmunity , vol.46 , pp. 138-147
    • Mannoor, K.1    Xu, Y.2    Chen, C.3
  • 278
    • 0034812467 scopus 로고    scopus 로고
    • Natural autoantibodies and complementpromote the uptake of a self antigen, human thyroglobulin,by B cells and the proliferation of thyroglobulinreactive CD4+T cells in healthy individuals
    • Nielsen CH, Leslie RGQ, Jepsen BS, Kazatchkine MD, Kaveri S V, Fischer E. Natural autoantibodies and complement promote the uptake of a self antigen, human thyroglobulin, by B cells and the proliferation of thyroglobulinreactive CD4+ T cells in healthy individuals. Eur J Immunol. 2001;31:2660-8.
    • (2001) Eur J Immunol , vol.31 , pp. 2660-2668
    • Nielsen, C.H.1    Leslie, R.2    Jepsen, B.S.3    Kazatchkine, M.D.4    Kaveri, S.V.5    Fischer, E.6
  • 279
    • 84873666705 scopus 로고    scopus 로고
    • The role of somatic hypermutation in the generation of pathogenic antibodies in SLE
    • Mar
    • Schroeder K, Herrmann M, Winkler TH. The role of somatic hypermutation in the generation of pathogenic antibodies in SLE. Autoimmunity. 2013 Mar;46:121-7.
    • (2013) Autoimmunity , vol.46 , pp. 121-127
    • Schroeder, K.1    Herrmann, M.2    Winkler, T.H.3
  • 280
    • 0031953639 scopus 로고    scopus 로고
    • Somatic hypermutation in autoimmune thyroid disease
    • Apr
    • McIntosh R, Watson P, Weetman A. Somatic hypermutation in autoimmune thyroid disease. Immunol Rev. 1998 Apr;162:219-31.
    • (1998) Immunol Rev , vol.162 , pp. 219-231
    • McIntosh, R.1    Watson, P.2    Weetman, A.3
  • 281
    • 0025741824 scopus 로고
    • CD24, a signal transducer modulating B cell activation responses, is a very short peptide with a glycosyl phosphatidylinositol membrane anchor
    • Aug 15
    • Kay R, Rosten PM, Humphries RK. CD24, a signal transducer modulating B cell activation responses, is a very short peptide with a glycosyl phosphatidylinositol membrane anchor. J Immunol. 1991 Aug 15;147:1412-6.
    • (1991) J Immunol , vol.147 , pp. 1412-1416
    • Kay, R.1    Rosten, P.M.2    Humphries, R.K.3
  • 282
    • 0026543876 scopus 로고
    • Heat-stable antigen is a costimulatory molecule for CD4 T cell growth
    • Feb 1
    • Liu Y, Jones B, Aruffo A, Sullivan K, Linsley P, Janeway C. Heat-stable antigen is a costimulatory molecule for CD4 T cell growth. J Exp Med. 1992 Feb 1;175:437-45.
    • (1992) J Exp Med , vol.175 , pp. 437-445
    • Liu, Y.1    Jones, B.2    Aruffo, A.3    Sullivan, K.4    Linsley, P.5    Janeway, C.6
  • 283
    • 0027993504 scopus 로고
    • Mapping of CD24 and homologous sequences to multiple chromosomal loci
    • Hough M, Rosten P, Sexton T, Kay R, Humphries RK. Mapping of CD24 and homologous sequences to multiple chromosomal loci. Genomics. 1994;22:154-61.
    • (1994) Genomics , vol.22 , pp. 154-161
    • Hough, M.1    Rosten, P.2    Sexton, T.3    Kay, R.4    Humphries, R.K.5
  • 284
    • 28044460035 scopus 로고    scopus 로고
    • Ray, Kane LP͘ T cellIg and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation
    • Nov 22;
    • De Souza J, Oriss TB, O’Malley KJ, Ray, Kane LP͘ T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation. Proc Natl Acad Sci U S A. 2005 Nov 22;102:17113-8.
    • (2005) Roc Natl Acad Sci U S A , vol.2 , pp. 7113-7118
    • De Souza, J.1    Oriss, T.B.2    O’Malley, K.J.3
  • 286
    • 38849166163 scopus 로고    scopus 로고
    • The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model
    • Ueno T, Habicht A, Clarkson MR, Albin MJ, Yamaura K, Boenisch O, et al. The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model. J Clin Invest. 2008;118:742-51.
    • (2008) J Clin Invest , vol.118 , pp. 742-751
    • Ueno, T.1    Habicht, A.2    Clarkson, M.R.3    Albin, M.J.4    Yamaura, K.5    Boenisch, O.6
  • 287
    • 38849120861 scopus 로고    scopus 로고
    • Immunostimulatory Tim-1 specific antibody deprograms Tregs and prevents transplant tolerance in mice
    • Degauque N, Mariat C, Kenny J, Zhang D, Gao W, Vu MD, et al. Immunostimulatory Tim-1 specific antibody deprograms Tregs and prevents transplant tolerance in mice. J Clin Invest. 2008;118:735-41.
    • (2008) J Clin Invest , vol.118 , pp. 735-741
    • Degauque, N.1    Mariat, C.2    Kenny, J.3    Zhang, D.4    Gao, W.5    Vu, M.D.6
  • 289
    • 81555221713 scopus 로고    scopus 로고
    • Phenotype and function of CD25-expressing B lymphocytes isolated from human umbilical cord blood
    • Jan
    • Amu S, Brisslert M. Phenotype and function of CD25-expressing B lymphocytes isolated from human umbilical cord blood. Clin Dev Immunol. 2011 Jan;2011:481948.
    • (2011) Clin Dev Immunol , vol.2011 , pp. 481948
    • Amu, S.1    Brisslert, M.2
  • 291
    • 84898799783 scopus 로고    scopus 로고
    • New regulatory CD19(+)CD25(+) B-cell subset in clinically isolated syndrome and multiple sclerosis relapse. Changes after glucocorticoids
    • May 15
    • De Andrés C, Tejera-Alhambra M, Alonso B, Valor L, Teijeiro R, Ramos-Medina R, et al. New regulatory CD19(+)CD25(+) B-cell subset in clinically isolated syndrome and multiple sclerosis relapse. Changes after glucocorticoids. J Neuroimmunol. Elsevier B.V.; 2014 May 15;270:37-44.
    • (2014) J Neuroimmunol. Elsevier B.V. , vol.270 , pp. 37-44
    • De Andrés, C.1    Tejera-Alhambra, M.2    Alonso, B.3    Valor, L.4    Teijeiro, R.5    Ramos-Medina, R.6
  • 292
    • 36248976097 scopus 로고    scopus 로고
    • CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells
    • Dec
    • Pandiyan P, Zheng L, Ishihara S, Reed J, Lenardo MJ. CD4+CD25+Foxp3+ regulatory T cells induce cytokine deprivation-mediated apoptosis of effector CD4+ T cells. Nat Immunol. 2007 Dec;8:1353-62.
    • (2007) Nat Immunol , vol.8 , pp. 1353-1362
    • Pandiyan, P.1    Zheng, L.2    Ishihara, S.3    Reed, J.4    Lenardo, M.J.5
  • 293
    • 84873313098 scopus 로고    scopus 로고
    • Rothstein TL͘ Human “orchestrator” CD11b+ B1 cells spontaneously secrete IL-10 and regulate T cell activity
    • Jan
    • Griffin DO, Rothstein TL͘ Human “orchestrator” CD11b+ B1 cells spontaneously secrete IL-10 and regulate T cell activity. Mol Med. 2012 Jan;18:1003-8.
    • (2012) Mol Med. , vol.18 , pp. 1003-1008
    • Griffin, D.O.1
  • 294
    • 84894157947 scopus 로고    scopus 로고
    • IL-10inhibits the NF-κB and ERK/MAPK-mediated production ofpro-inflammatory mediators by up-regulation of SOCS-3 inTrypanosoma cruzi-infected cardiomyocytes
    • Jan
    • Hovsepian E, Penas F, Siffo S, Mirkin GA, Goren NB. IL-10 inhibits the NF-κB and ERK/MAPK-mediated production of pro-inflammatory mediators by up-regulation of SOCS-3 in Trypanosoma cruzi-infected cardiomyocytes. PLoS One. 2013 Jan;8:e79445.
    • (2013) Plos One , vol.8
    • Hovsepian, E.1    Penas, F.2    Siffo, S.3    Mirkin, G.A.4    Goren, N.B.5
  • 295
    • 0031183766 scopus 로고    scopus 로고
    • The role of nuclear factor-kappa B in cytokine gene regulation
    • Jul
    • Blackwell T, Christman J. The role of nuclear factor-kappa B in cytokine gene regulation. Am J Respir Cell Mol Biol. 1997 Jul;17:3-9.
    • (1997) Am J Respir Cell Mol Biol , vol.17 , pp. 3-9
    • Blackwell, T.1    Christman, J.2
  • 296
    • 0034746919 scopus 로고    scopus 로고
    • NFκB : A key role in inflammatory diseases
    • Tak PP, Firestein GS. NFκB : a key role in inflammatory diseases. J Clin Invest. 2001;107:7-11.
    • (2001) J Clin Invest , vol.107 , pp. 7-11
    • Tak, P.P.1    Firestein, G.S.2
  • 297
    • 84907020059 scopus 로고    scopus 로고
    • Human Regulatory B Cells Combine Phenotypic and Genetic Hallmarks with a Distinct Differentiation Fate
    • Jul 30
    • Lin W, Cerny D, Chua E, Duan K, Yi JTJ, Shadan NB, et al. Human Regulatory B Cells Combine Phenotypic and Genetic Hallmarks with a Distinct Differentiation Fate. J Immunol. 2014 Jul 30;193:2258-66.
    • (2014) J Immunol , vol.193 , pp. 2258-2266
    • Lin, W.1    Cerny, D.2    Chua, E.3    Duan, K.4    Yi, J.5    Shadan, N.B.6
  • 299
    • 39149113772 scopus 로고    scopus 로고
    • Antigen presentation by monocytes and monocyte-derived cells
    • Randolph G, Jakubzick C, Qu C. Antigen presentation by monocytes and monocyte-derived cells. Curr Opin Immunol. 2008;20:52-60.
    • (2008) Curr Opin Immunol , vol.20 , pp. 52-60
    • Randolph, G.1    Jakubzick, C.2    Qu, C.3
  • 300
    • 0020551673 scopus 로고
    • Antigen presentation by humanmonocytes: Evidence for stimulant processing and requirement for interleukin 1
    • Sep
    • Scala G, Oppenheim J. Antigen presentation by human monocytes: evidence for stimulant processing and requirement for interleukin 1. J Immunol. 1983 Sep;131:1160-6.
    • (1983) J Immunol , vol.131 , pp. 1160-1166
    • Scala, G.1    Oppenheim, J.2
  • 301
    • 0025248775 scopus 로고
    • Interleukin-1 induces interleukin-6 production in peripheral blood monocytes
    • Tosato G, Jones K. Interleukin-1 induces interleukin-6 production in peripheral blood monocytes. Blood. 1990;75:1305-10.
    • (1990) Blood , vol.75 , pp. 1305-1310
    • Tosato, G.1    Jones, K.2
  • 302
    • 0029872051 scopus 로고    scopus 로고
    • Comparison of Monocytes and B Cells for Activation of Human T Helper Cell Subsets
    • Beck L, Roth R, Spiegelberg H. Comparison of Monocytes and B Cells for Activation of Human T Helper Cell Subsets. Clin Immunol Immunopathol. 1996;78:56-60.
    • (1996) Clin Immunol Immunopathol , vol.78 , pp. 56-60
    • Beck, L.1    Roth, R.2    Spiegelberg, H.3
  • 303
    • 0029157151 scopus 로고
    • B Lymphocytes can be competent antigen-presenting cells for priming CD4+ T cells to protein antigens in vivo
    • Constant S, Schweitzer N, West J, Ranney P, Bottomly K. B Lymphocytes can be competent antigen-presenting cells for priming CD4+ T cells to protein antigens in vivo. J Immunol. 1995;155:3734-41.
    • (1995) J Immunol , vol.155 , pp. 3734-3741
    • Constant, S.1    Schweitzer, N.2    West, J.3    Ranney, P.4    Bottomly, K.5
  • 304
    • 33646036416 scopus 로고    scopus 로고
    • B cells as antigen presenting cells
    • Dec
    • Rodríguez-Pinto D. B cells as antigen presenting cells. Cell Immunol. 2005 Dec;238:67-75.
    • (2005) Cell Immunol , vol.238 , pp. 67-75
    • Rodríguez-Pinto, D.1
  • 305
    • 0033980502 scopus 로고    scopus 로고
    • Evidence for antigen presentation to sensitized T cells by thyroid peroxidase (TPO)-specific B cells in mice injected with fibroblasts coexpressing TPO and MHC class II
    • Guo J, Wang Y, Rapoport B, McLachlan SM. Evidence for antigen presentation to sensitized T cells by thyroid peroxidase (TPO)-specific B cells in mice injected with fibroblasts coexpressing TPO and MHC class II. Clin Exp Immunol. 2000;119:38-46.
    • (2000) Clin Exp Immunol , vol.119 , pp. 38-46
    • Guo, J.1    Wang, Y.2    Rapoport, B.3    McLachlan, S.M.4
  • 306
    • 0030636560 scopus 로고    scopus 로고
    • Van,Dohlsten M. Immunoregulatory Role of IL-10 During Superantigen-Induced Hyporesponsives In Vivo
    • Sundstedt A, Rosendahl A, Kalland T, Rooijen N Van, Dohlsten M. Immunoregulatory Role of IL-10 During Superantigen-Induced Hyporesponsives In Vivo. J Immunol. 1997;158:180-6.
    • (1997) J Immunol , vol.158 , pp. 180-186
    • Sundstedt, A.1    Rosendahl, A.2    Kalland, T.3    Rooijen, N.4
  • 307
    • 0027239842 scopus 로고
    • IL-10 Inhibits Macrophage Costimulatory Activity by Selectively Inhibiting the Upregulation of B7 Expression
    • Ding L, Linsley PS, Huang L, Shevach EM, Germain N. IL-10 Inhibits Macrophage Costimulatory Activity by Selectively Inhibiting the Upregulation of B7 Expression. J Immunol. 1993;151:1224-34.
    • (1993) J Immunol , vol.151 , pp. 1224-1234
    • Ding, L.1    Linsley, P.S.2    Huang, L.3    Shevach, E.M.4    Germain, N.5
  • 308
    • 84881453041 scopus 로고    scopus 로고
    • Impairment of regulatory T-cell function in autoimmune thyroid disease
    • Jul
    • Glick AB, Wodzinski A, Fu P, Levine AD, Wald DN. Impairment of regulatory T-cell function in autoimmune thyroid disease. Thyroid. 2013 Jul;23:871-8.
    • (2013) Thyroid , vol.23 , pp. 871-878
    • Glick, A.B.1    Wodzinski, A.2    Fu, P.3    Levine, A.D.4    Wald, D.N.5
  • 311
    • 33846804394 scopus 로고    scopus 로고
    • Apoptosis-induced decrease of intrathyroidal CD4+CD25+ Regulatory T Cells in Autoimmune Thyroid Diseases
    • Nakano A, Watanabe M, Iida T, Kuroda S, Matsuzuka F, Miyauchi A, et al. Apoptosis-induced decrease of intrathyroidal CD4+CD25+ Regulatory T Cells in Autoimmune Thyroid Diseases. Thyroid. 2007;17:25-31.
    • (2007) Thyroid , vol.17 , pp. 25-31
    • Nakano, A.1    Watanabe, M.2    Iida, T.3    Kuroda, S.4    Matsuzuka, F.5    Miyauchi, A.6
  • 312
    • 77954688261 scopus 로고    scopus 로고
    • Potent intestinal Th17 priming through peripheral lipopolysaccharide-based immunization
    • Jul
    • McAleer JP, Liu B, Li Z, Ngoi S-M, Dai J, Oft M, et al. Potent intestinal Th17 priming through peripheral lipopolysaccharide-based immunization. J Leukoc Biol. 2010 Jul;88:21-31.
    • (2010) J Leukoc Biol , vol.88 , pp. 21-31
    • McAleer, J.P.1    Liu, B.2    Li, Z.3    Ngoi, S.-M.4    Dai, J.5    Oft, M.6
  • 313
    • 36749081557 scopus 로고    scopus 로고
    • Optimal induction of T helper 17 cells in humans requires T cellreceptor ligation in the context of Toll-like receptor-activatedmonocytes
    • Oct 23
    • Evans HG, Suddason T, Jackson I, Taams LS, Lord GM. Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes. Proc Natl Acad Sci U S A. 2007 Oct 23;104:17034-9.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 17034-17039
    • Evans, H.G.1    Suddason, T.2    Jackson, I.3    Taams, L.S.4    Lord, G.M.5
  • 314
    • 32244442562 scopus 로고    scopus 로고
    • TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
    • Feb
    • Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B. TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity. 2006 Feb;24:179-89.
    • (2006) Immunity , vol.24 , pp. 179-189
    • Veldhoen, M.1    Hocking, R.J.2    Atkins, C.J.3    Locksley, R.M.4    Stockinger, B.5
  • 315
    • 17144400393 scopus 로고    scopus 로고
    • TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells
    • Apr 4
    • Marie JC, Letterio JJ, Gavin M, Rudensky AY. TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells. J Exp Med. 2005 Apr 4;201:1061-7.
    • (2005) J Exp Med , vol.201 , pp. 1061-1067
    • Marie, J.C.1    Letterio, J.J.2    Gavin, M.3    Rudensky, A.Y.4
  • 316
    • 37849048599 scopus 로고    scopus 로고
    • Th17 lineage differentiation is programmed by orphan nuclear receptors RORa and RORy
    • Yang XO, Pappu B, Nurieva R, Akimzhanov A, Soon H, Chung Y, et al. Th17 lineage differentiation is programmed by orphan nuclear receptors RORa and RORy. Immunity. 2008;28:29-39.
    • (2008) Immunity , vol.28 , pp. 29-39
    • Yang, X.O.1    Pappu, B.2    Nurieva, R.3    Akimzhanov, A.4    Soon, H.5    Chung, Y.6
  • 317
    • 72949103063 scopus 로고    scopus 로고
    • Translational mini-review series on Th17 cells: Development of mouse and human Thelper 17 cells
    • Feb
    • De Jong E, Suddason T, Lord G. Translational mini-review series on Th17 cells: development of mouse and human Thelper 17 cells. Clin Exp Immunol. 2010 Feb;159:148-58.
    • (2010) Clin Exp Immunol , vol.159 , pp. 148-158
    • De Jong, E.1    Suddason, T.2    Lord, G.3
  • 318
    • 63449129385 scopus 로고    scopus 로고
    • Systematic method for determining an ideal housekeeping gene for real-time PCR analysis
    • Dec
    • Mane VP, Heuer MA, Hillyer P, Navarro MB, Rabin RL. Systematic method for determining an ideal housekeeping gene for real-time PCR analysis. J Biomol Tech. 2008 Dec;19:342-7.
    • (2008) J Biomol Tech , vol.19 , pp. 342-347
    • Mane, V.P.1    Heuer, M.A.2    Hillyer, P.3    Navarro, M.B.4    Rabin, R.L.5
  • 320
    • 1642513794 scopus 로고    scopus 로고
    • Autoantibodies in autoimmune thyroid disease promote immune complex formation with self antigens and increase B cell and CD4+ T cell proliferation in response to self antigens
    • Nielsen CH, Hegedüs L, Leslie RGQ. Autoantibodies in autoimmune thyroid disease promote immune complex formation with self antigens and increase B cell and CD4+ T cell proliferation in response to self antigens. Eur J Immunol. 2004;34:263-72.
    • (2004) Eur J Immunol , vol.34 , pp. 263-272
    • Nielsen, C.H.1    Hegedüs, L.2    Leslie, R.G.Q.3
  • 321
    • 33744995604 scopus 로고    scopus 로고
    • Self-Reactive CD4+ T Cells and B Cells in the Blood in Health and Autoimmune Disease: Increased Frequency of Thyroglobulin-Reactive Cells in Graves
    • Nielsen CH, Moeller AC, Hegedüs L, Bendtzen K, Leslie RGQ. Self-Reactive CD4+ T Cells and B Cells in the Blood in Health and Autoimmune Disease: Increased Frequency of Thyroglobulin-Reactive Cells in Graves’ Disease͘ J Clin Immunol. 2006;26:126-37.
    • (2006) Disease͘ J Clin Immunol , vol.26 , pp. 126-137
    • Nielsen, C.H.1    Moeller, A.C.2    Hegedüs, L.3    Bendtzen, K.4    Leslie, R.5
  • 322
    • 33846204725 scopus 로고    scopus 로고
    • Production of interleukin (IL)-5 and IL-10 accompanies T helper cell type 1 (Th1) cytokine responses to a major thyroid self-antigen, thyroglobulin, in health and autoimmune thyroid disease
    • Feb
    • Nielsen C, Hegedüs L, Rieneck K, Moeller A, Leslie R, Bendtzen K. Production of interleukin (IL)-5 and IL-10 accompanies T helper cell type 1 (Th1) cytokine responses to a major thyroid self-antigen, thyroglobulin, in health and autoimmune thyroid disease. Clin Exp Immunol. 2007 Feb;147:287-95.
    • (2007) Clin Exp Immunol , vol.147 , pp. 287-295
    • Nielsen, C.1    Hegedüs, L.2    Rieneck, K.3    Moeller, A.4    Leslie, R.5    Bendtzen, K.6
  • 323
    • 0019760458 scopus 로고
    • Inhibition of immunoglobulin-secreting cells by antithyroid drugs
    • Dec
    • Weiss I, Davies TF. Inhibition of immunoglobulin-secreting cells by antithyroid drugs. J Clin Endocrinol Metab. 1981 Dec;53:1223-8.
    • (1981) J Clin Endocrinol Metab , vol.53 , pp. 1223-1228
    • Weiss, I.1    Davies, T.F.2
  • 324
    • 40849147275 scopus 로고    scopus 로고
    • Thionamides Inhibit the TranscriptionFactor Nuclear Factor-kappa B by Suppression of Rac1 and Inhibitor of kappaB Kinase alpha
    • Humar M, Dohrmann H, Stein P, Andriopoulos N, Goebel U, Roesslein M, et al. Thionamides Inhibit the Transcription Factor Nuclear Factor-kappa B by Suppression of Rac1 and Inhibitor of kappaB Kinase alpha. J Pharmacol Exp Ther. 2008;324:1037-44.
    • (2008) J Pharmacol Exp Ther , vol.324 , pp. 1037-1044
    • Humar, M.1    Dohrmann, H.2    Stein, P.3    Riopoulos, N.4    Goebel, U.5    Roesslein, M.6
  • 325
    • 0035036186 scopus 로고    scopus 로고
    • The immunomodulatory effects of anti-thyroiddrugs are mediated via actions on thyroid cells, affecting thyrocyte-immunocyte signalling: A review
    • Apr
    • Volpé R. The immunomodulatory effects of anti-thyroid drugs are mediated via actions on thyroid cells, affecting thyrocyte-immunocyte signalling: a review. Curr Pharm Des. 2001 Apr;7:451-60.
    • (2001) Curr Pharm Des , vol.7 , pp. 451-460
    • Volpé, R.1
  • 327
    • 84897027520 scopus 로고    scopus 로고
    • IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases
    • Mar 20
    • Shen P, Roch T, Lampropoulou V, O’Connor R, Stervbo U, Hilgenberg E, et al. IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases. Nature. 2014 Mar 20;507:366-70.
    • (2014) Nature , vol.507 , pp. 366-370
    • Shen, P.1    Roch, T.2    Lampropoulou, V.3    O’Connor, R.4    Stervbo, U.5    Hilgenberg, E.6
  • 328
    • 84876292569 scopus 로고    scopus 로고
    • Effect of IL-17A blockade with secukinumab in autoimmune diseases
    • Apr
    • Patel DD, Lee DM, Kolbinger F, Antoni C. Effect of IL-17A blockade with secukinumab in autoimmune diseases. Ann Rheum Dis. 2013 Apr;72:2116-2123.
    • (2013) Ann Rheum Dis , vol.72 , pp. 2116-2123
    • Patel, D.D.1    Lee, D.M.2    Kolbinger, F.3    Antoni, C.4
  • 329
    • 84887444732 scopus 로고    scopus 로고
    • Targeting interleukin-17 in patients with active rheumatoid arthritis: Rationale and clinical potential
    • Jun
    • Kellner H. Targeting interleukin-17 in patients with active rheumatoid arthritis: rationale and clinical potential. Ther Adv Musculoskelet Dis. 2013 Jun;5:141-52.
    • (2013) Ther Adv Musculoskelet Dis , vol.5 , pp. 141-152
    • Kellner, H.1
  • 330
    • 84906316949 scopus 로고    scopus 로고
    • Inhibiting RORγt/Th17 axisfor autoimmune disorders
    • Aug
    • Isono F, Fujita-Sato S, Ito S. Inhibiting RORγt/Th17 axis for autoimmune disorders. Drug Discov Today. 2014 Aug;19:1205-11.
    • (2014) Drug Discov Today , vol.19 , pp. 1205-1211
    • Isono, F.1    Fujita-Sato, S.2    Ito, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.