-
1
-
-
49449117005
-
The role of inflammatory cytokines in diabetes and its complications
-
King GL (2008) The role of inflammatory cytokines in diabetes and its complications. J Periodontol 79:1527-1534.
-
(2008)
J Periodontol
, vol.79
, pp. 1527-1534
-
-
King, G.L.1
-
2
-
-
0038691972
-
Low-grade systemic inflammation and the development of type 2 diabetes: The atherosclerosis risk in communities study
-
Duncan BB, Schmidt MI, Pankow JS et al (2003) Low-grade systemic inflammation and the development of type 2 diabetes: the atherosclerosis risk in communities study. Diabetes 52:1799-1805.
-
(2003)
Diabetes
, vol.52
, pp. 1799-1805
-
-
Duncan, B.B.1
Schmidt, M.I.2
Pankow, J.S.3
-
3
-
-
0345700727
-
Inflammatory cytokines and the risk to develop type 2 diabetes: Results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study
-
Spranger J, Kroke A, Mohlig M et al (2003) Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer and Nutrition (EPIC)-Potsdam Study. Diabetes 52:812-817.
-
(2003)
Diabetes
, vol.52
, pp. 812-817
-
-
Spranger, J.1
Kroke, A.2
Mohlig, M.3
-
4
-
-
33947182436
-
Lipopoly-saccharide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes
-
Creely SJ, McTernan PG, Kusminski CM et al (2007) Lipopoly-saccharide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes. Am J Physiol Endocrinol Metab 292:E740-E747.
-
(2007)
Am J Physiol Endocrinol Metab
, vol.292
-
-
Creely, S.J.1
McTernan, P.G.2
Kusminski, C.M.3
-
5
-
-
33750584214
-
TLR4 links innate immunity and fatty acid-induced insulin resistance
-
Shi H, Kokoeva MV, Inouye K, Tzameli I, Yin H, Flier JS (2006) TLR4 links innate immunity and fatty acid-induced insulin resistance. J Clin Invest 116:3015-3025.
-
(2006)
J Clin Invest
, vol.116
, pp. 3015-3025
-
-
Shi, H.1
Kokoeva, M.V.2
Inouye, K.3
Tzameli, I.4
Yin, H.5
Flier, J.S.6
-
6
-
-
0025811915
-
The role of inflammatory mediators in the pathogenesis of periodontal disease
-
Page RC (1991) The role of inflammatory mediators in the pathogenesis of periodontal disease. J Periodontal Res 26:230-242.
-
(1991)
J Periodontal Res
, vol.26
, pp. 230-242
-
-
Page, R.C.1
-
7
-
-
34247884376
-
C3H/HeJ mice carrying a Toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet
-
Poggi M, Bastelica D, Gual P et al (2007) C3H/HeJ mice carrying a Toll-like receptor 4 mutation are protected against the development of insulin resistance in white adipose tissue in response to a high-fat diet. Diabetologia 50:1267-1276.
-
(2007)
Diabetologia
, vol.50
, pp. 1267-1276
-
-
Poggi, M.1
Bastelica, D.2
Gual, P.3
-
8
-
-
34547602916
-
Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance
-
Tsukumo DM, Carvalho-Filho MA, Carvalheira JB et al (2007) Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance. Diabetes 56:1986-1998.
-
(2007)
Diabetes
, vol.56
, pp. 1986-1998
-
-
Tsukumo, D.M.1
Carvalho-Filho, M.A.2
Carvalheira, J.B.3
-
9
-
-
57449083385
-
Inhibition of toll-like receptor 2 expression improves insulin sensitivity and signaling in muscle and white adipose tissue of mice fed a high-fat diet
-
Caricilli AM, Nascimento PH, Pauli JR et al (2008) Inhibition of toll-like receptor 2 expression improves insulin sensitivity and signaling in muscle and white adipose tissue of mice fed a high-fat diet. J Endocrinol 199:399-406.
-
(2008)
J Endocrinol
, vol.199
, pp. 399-406
-
-
Caricilli, A.M.1
Nascimento, P.H.2
Pauli, J.R.3
-
10
-
-
77953135609
-
Toll-like receptor 4 and inducible nitric oxide synthase gene polymorphisms are associated with type 2 diabetes
-
doi:10.1016/j.jdiacomp.2009.03.003
-
Bagarolli RA, Saad MJ, Saad ST (2010) Toll-like receptor 4 and inducible nitric oxide synthase gene polymorphisms are associated with type 2 diabetes. J Diabetes Complications. doi:10.1016/j.jdiacomp.2009.03.003.
-
(2010)
J Diabetes Complications
-
-
Bagarolli, R.A.1
Saad, M.J.2
Saad, S.T.3
-
11
-
-
42049098225
-
Association between variations in the TLR4 gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol
-
Kolz M, Baumert J, Muller M et al (2008) Association between variations in the TLR4 gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol. BMC Med Genet 9:9.
-
(2008)
BMC Med Genet
, vol.9
, pp. 9
-
-
Kolz, M.1
Baumert, J.2
Muller, M.3
-
12
-
-
14544306143
-
Association of the polymorphism for Toll-like receptor 2 with type 1 diabetes susceptibility
-
Park Y, Park S, Yoo E, Kim D, Shin H (2004) Association of the polymorphism for Toll-like receptor 2 with type 1 diabetes susceptibility. Ann N Y Acad Sci 1037:170-174.
-
(2004)
Ann N Y Acad Sci
, vol.1037
, pp. 170-174
-
-
Park, Y.1
Park, S.2
Yoo, E.3
Kim, D.4
Shin, H.5
-
13
-
-
73349120965
-
Toll-like receptor cross talk specifically regulates cytokine production by B cells from chronic inflammatory disease patients
-
Jagannathan M, Hasturk H, Liang Yet al (2009) Toll-like receptor cross talk specifically regulates cytokine production by B cells from chronic inflammatory disease patients. J Immunol 183:7461-7470.
-
(2009)
J Immunol
, vol.183
, pp. 7461-7470
-
-
Jagannathan, M.1
Hasturk, H.2
Liang, Y.A.3
-
14
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
-
Leadbetter EA, Rifkin IR, Hohlbaum AM, Beaudette BC, Shlomchik MJ, Marshak-Rothstein A (2002) Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 416:603-607.
-
(2002)
Nature
, vol.416
, pp. 603-607
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
15
-
-
0041743207
-
The toll-like receptor repertoire of human B lymphocytes: Inducible and selective expression of TLR9 and TLR10 in normal and transformed cells
-
Bourke E, Bosisio D, Golay J, Polentarutti N, Mantovani A (2003) The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells. Blood 102:956-963.
-
(2003)
Blood
, vol.102
, pp. 956-963
-
-
Bourke, E.1
Bosisio, D.2
Golay, J.3
Polentarutti, N.4
Mantovani, A.5
-
16
-
-
0036570169
-
Quantitative expression of Toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
-
Hornung V, Rothenfusser S, Britsch S et al (2002) Quantitative expression of Toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol 168:4531-4537.
-
(2002)
J Immunol
, vol.168
, pp. 4531-4537
-
-
Hornung, V.1
Rothenfusser, S.2
Britsch, S.3
-
17
-
-
1542514778
-
Distinct profiles of human B cell effector cytokines: A role in immune regulation?
-
Duddy ME, Alter A, Bar-Or A (2004) Distinct profiles of human B cell effector cytokines: a role in immune regulation? J Immunol 172:3422-3427.
-
(2004)
J Immunol
, vol.172
, pp. 3422-3427
-
-
Duddy, M.E.1
Alter, A.2
Bar-Or, A.3
-
18
-
-
49249088078
-
Comparison of human B cell activation by TLR7 and TLR9 agonists
-
Hanten JA, Vasilakos JP, Riter CL et al (2008) Comparison of human B cell activation by TLR7 and TLR9 agonists. BMC Immunol 9:39.
-
(2008)
BMC Immunol
, vol.9
, pp. 39
-
-
Hanten, J.A.1
Vasilakos, J.P.2
Riter, C.L.3
-
19
-
-
65249083921
-
B cells from periodontal disease patients express surface Toll-like receptor 4
-
Shin H, Zhang Y, Jagannathan M et al (2009) B cells from periodontal disease patients express surface Toll-like receptor 4. J Leukoc Biol 85:648-655.
-
(2009)
J Leukoc Biol
, vol.85
, pp. 648-655
-
-
Shin, H.1
Zhang, Y.2
Jagannathan, M.3
-
20
-
-
70349640926
-
Hyperactivated B cells in human inflammatory bowel disease
-
Noronha AM, Liang Y, Hetzel JT et al (2009) Hyperactivated B cells in human inflammatory bowel disease. J Leukoc Biol 86:1007-1016.
-
(2009)
J Leukoc Biol
, vol.86
, pp. 1007-1016
-
-
Noronha, A.M.1
Liang, Y.2
Hetzel, J.T.3
-
21
-
-
34248230257
-
Distinct effector cytokine profiles of memory and naive human B cell subsets and implication in multiple sclerosis
-
Duddy M, Niino M, Adatia F et al (2007) Distinct effector cytokine profiles of memory and naive human B cell subsets and implication in multiple sclerosis. J Immunol 178:6092-6099.
-
(2007)
J Immunol
, vol.178
, pp. 6092-6099
-
-
Duddy, M.1
Niino, M.2
Adatia, F.3
-
22
-
-
74649083783
-
CD19(+)CD24 (hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients
-
Blair PA, Norena LY, Flores-Borja F et al (2010) CD19(+)CD24 (hi)CD38(hi) B cells exhibit regulatory capacity in healthy individuals but are functionally impaired in systemic lupus erythematosus patients. Immunity 32:129-140.
-
(2010)
Immunity
, vol.32
, pp. 129-140
-
-
Blair, P.A.1
Norena, L.Y.2
Flores-Borja, F.3
-
23
-
-
0036795531
-
B cells regulate autoimmunity by provision of IL-10
-
Fillatreau S, Sweenie CH, McGeachy MJ, Gray D, Anderton SM (2002) B cells regulate autoimmunity by provision of IL-10. Nat Immunol 3:944-950.
-
(2002)
Nat Immunol
, vol.3
, pp. 944-950
-
-
Fillatreau, S.1
Sweenie, C.H.2
McGeachy, M.J.3
Gray, D.4
Anderton, S.M.5
-
24
-
-
0037333555
-
Down-regulation of Th1-mediated pathology in experimental arthritis by stimulation of the Th2 arm of the immune response
-
Mauri C, Feldmann M, Williams RO (2003) Down-regulation of Th1-mediated pathology in experimental arthritis by stimulation of the Th2 arm of the immune response. Arthritis Rheum 48:839-845.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 839-845
-
-
Mauri, C.1
Feldmann, M.2
Williams, R.O.3
-
25
-
-
0036224269
-
Low production capacity of interleukin-10 associates with the metabolic syndrome and type 2 diabetes: The Leiden 85-Plus Study
-
van Exel E, Gussekloo J, de Craen AJ, Frolich M, Bootsma-Van Der Wiel A, Westendorp RG (2002) Low production capacity of interleukin-10 associates with the metabolic syndrome and type 2 diabetes: the Leiden 85-Plus Study. Diabetes 51:1088-1092.
-
(2002)
Diabetes
, vol.51
, pp. 1088-1092
-
-
Van Exel, E.1
Gussekloo, J.2
De Craen, A.J.3
Frolich, M.4
Bootsma-Van Der Wiel, A.5
Westendorp, R.G.6
-
26
-
-
42649111367
-
TLR-activated B cells suppress T cell-mediated autoimmunity
-
Lampropoulou V, Hoehlig K, Roch T et al (2008) TLR-activated B cells suppress T cell-mediated autoimmunity. J Immunol 180:4763-4773.
-
(2008)
J Immunol
, vol.180
, pp. 4763-4773
-
-
Lampropoulou, V.1
Hoehlig, K.2
Roch, T.3
-
27
-
-
34247601196
-
Diabetes mellitus and periodontal disease
-
Mealey BL, Ocampo GL (2007) Diabetes mellitus and periodontal disease. Periodontol 2000 44:127-153.
-
(2007)
Periodontol 2000
, vol.44
, pp. 127-153
-
-
Mealey, B.L.1
Ocampo, G.L.2
-
28
-
-
0036312978
-
C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study
-
Freeman DJ, Norrie J, Caslake MJ et al (2002) C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study. Diabetes 51:1596-1600.
-
(2002)
Diabetes
, vol.51
, pp. 1596-1600
-
-
Freeman, D.J.1
Norrie, J.2
Caslake, M.J.3
-
29
-
-
3242662149
-
C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham Offspring Study
-
Rutter MK, Meigs JB, Sullivan LM, D'Agostino RB Sr, Wilson PW (2004) C-reactive protein, the metabolic syndrome, and prediction of cardiovascular events in the Framingham Offspring Study. Circulation 110:380-385.
-
(2004)
Circulation
, vol.110
, pp. 380-385
-
-
Rutter, M.K.1
Meigs, J.B.2
Sullivan, L.M.3
D'Agostino Sr., R.B.4
Wilson, P.W.5
-
30
-
-
0033288546
-
Development of a classification system for periodontal diseases and conditions
-
Armitage GC (1999) Development of a classification system for periodontal diseases and conditions. Ann Periodontol 4:1-6.
-
(1999)
Ann Periodontol
, vol.4
, pp. 1-6
-
-
Armitage, G.C.1
-
31
-
-
0026088437
-
Lipid A-like molecules that antagonize the effects of endotoxins on human monocytes
-
Golenbock DT, Hampton RY, Qureshi N, Takayama K, Raetz CR (1991) Lipid A-like molecules that antagonize the effects of endotoxins on human monocytes. J Biol Chem 266:19490-19498.
-
(1991)
J Biol Chem
, vol.266
, pp. 19490-19498
-
-
Golenbock, D.T.1
Hampton, R.Y.2
Qureshi, N.3
Takayama, K.4
Raetz, C.R.5
-
32
-
-
0035888026
-
Chromatin remodeling, measured by a novel real-time polymerase chain reaction assay, across the proximal promoter region of the IL-2 gene
-
Rao S, Procko E, Shannon MF (2001) Chromatin remodeling, measured by a novel real-time polymerase chain reaction assay, across the proximal promoter region of the IL-2 gene. J Immunol 167:4494-4503.
-
(2001)
J Immunol
, vol.167
, pp. 4494-4503
-
-
Rao, S.1
Procko, E.2
Shannon, M.F.3
-
33
-
-
33746854297
-
Toll-like receptor 2-mediated human B cell differentiation
-
Ganley-Leal LM, Liu X, Wetzler LM (2006) Toll-like receptor 2-mediated human B cell differentiation. Clin Immunol 120:272-284.
-
(2006)
Clin Immunol
, vol.120
, pp. 272-284
-
-
Ganley-Leal, L.M.1
Liu, X.2
Wetzler, L.M.3
-
34
-
-
77953060025
-
Increased Toll-like receptor activation and TLR ligands in recently diagnosed type 2 diabetes subjects
-
doi:10.2337/dc09-1799
-
Dasu MR, Devaraj S, Park S, Jialal I (2010) Increased Toll-like receptor activation and TLR ligands in recently diagnosed type 2 diabetes subjects. Diabetes Care. doi:10.2337/dc09-1799.
-
(2010)
Diabetes Care
-
-
Dasu, M.R.1
Devaraj, S.2
Park, S.3
Jialal, I.4
-
35
-
-
33344466383
-
Defective acute inflammation in Crohn's disease: A clinical investigation
-
Marks DJ, Harbord MW, MacAllister R et al (2006) Defective acute inflammation in Crohn's disease: a clinical investigation. Lancet 367:668-678.
-
(2006)
Lancet
, vol.367
, pp. 668-678
-
-
Marks, D.J.1
Harbord, M.W.2
MacAllister, R.3
-
36
-
-
4544337512
-
Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both toll-like receptors 2 and 4
-
Darveau RP, Pham TT, Lemley K et al (2004) Porphyromonas gingivalis lipopolysaccharide contains multiple lipid A species that functionally interact with both toll-like receptors 2 and 4. Infect Immun 72:5041-5051.
-
(2004)
Infect Immun
, vol.72
, pp. 5041-5051
-
-
Darveau, R.P.1
Pham, T.T.2
Lemley, K.3
-
37
-
-
33748755008
-
Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes
-
Senn JJ (2006) Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes. J Biol Chem 281:26865-26875.
-
(2006)
J Biol Chem
, vol.281
, pp. 26865-26875
-
-
Senn, J.J.1
-
38
-
-
68349137821
-
Normalization of obesity-associated insulin resistance through immunotherapy
-
Winer S, Chan Y, Paltser G et al (2009) Normalization of obesity-associated insulin resistance through immunotherapy. Nat Med 15:921-929.
-
(2009)
Nat Med
, vol.15
, pp. 921-929
-
-
Winer, S.1
Chan, Y.2
Paltser, G.3
-
39
-
-
68349148211
-
Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
-
Feuerer M, Herrero L, Cipolletta D et al (2009) Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters. Nat Med 15:930-939.
-
(2009)
Nat Med
, vol.15
, pp. 930-939
-
-
Feuerer, M.1
Herrero, L.2
Cipolletta, D.3
-
40
-
-
68349150756
-
CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
-
Nishimura S, Manabe I, Nagasaki M et al (2009) CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 15:914-920.
-
(2009)
Nat Med
, vol.15
, pp. 914-920
-
-
Nishimura, S.1
Manabe, I.2
Nagasaki, M.3
-
41
-
-
33644594409
-
Association of systemic chemokine concentrations with impaired glucose tolerance and type 2 diabetes: Results from the Cooperative Health Research in the Region of Augsburg Survey S4 (KORA S4)
-
Herder C, Haastert B, Muller-Scholze S et al (2005) Association of systemic chemokine concentrations with impaired glucose tolerance and type 2 diabetes: results from the Cooperative Health Research in the Region of Augsburg Survey S4 (KORA S4). Diabetes 54(Suppl 2):S11-S17.
-
(2005)
Diabetes
, vol.54
, Issue.SUPPL. 2
-
-
Herder, C.1
Haastert, B.2
Muller-Scholze, S.3
-
42
-
-
33846201363
-
Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells
-
Fain JN (2006) Release of interleukins and other inflammatory cytokines by human adipose tissue is enhanced in obesity and primarily due to the nonfat cells. Vitam Horm 74:443-477.
-
(2006)
Vitam Horm
, vol.74
, pp. 443-477
-
-
Fain, J.N.1
-
43
-
-
0043237804
-
Plasma levels of IL-8 predict early complications in patients with coronary heart disease after percutaneous coronary intervention
-
Qi X, Li J, Gu J, Li S, Dang Y, Wang T (2003) Plasma levels of IL-8 predict early complications in patients with coronary heart disease after percutaneous coronary intervention. Jpn Heart J 44:451-461.
-
(2003)
Jpn Heart J
, vol.44
, pp. 451-461
-
-
Qi, X.1
Li, J.2
Gu, J.3
Li, S.4
Dang, Y.5
Wang, T.6
-
44
-
-
0034470214
-
Interleukin-8 production in human adipose tissue. Inhibitory effects of anti-diabetic compounds, the thiazolidinedione ciglitazone and the biguanide metformin
-
Bruun JM, Pedersen SB, Richelsen B (2000) Interleukin-8 production in human adipose tissue. inhibitory effects of anti-diabetic compounds, the thiazolidinedione ciglitazone and the biguanide metformin. Horm Metab Res 32:537-541.
-
(2000)
Horm Metab Res
, vol.32
, pp. 537-541
-
-
Bruun, J.M.1
Pedersen, S.B.2
Richelsen, B.3
-
45
-
-
0030756346
-
Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function
-
Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS (1997) Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function. Nature 389:610-614.
-
(1997)
Nature
, vol.389
, pp. 610-614
-
-
Uysal, K.T.1
Wiesbrock, S.M.2
Marino, M.W.3
Hotamisligil, G.S.4
-
46
-
-
34247170807
-
Interleukin-1-receptor antagonist in type 2 diabetes mellitus
-
Larsen CM, Faulenbach M, Vaag A et al (2007) Interleukin-1-receptor antagonist in type 2 diabetes mellitus. N Engl J Med 356:1517-1526.
-
(2007)
N Engl J Med
, vol.356
, pp. 1517-1526
-
-
Larsen, C.M.1
Faulenbach, M.2
Vaag, A.3
-
47
-
-
0029906375
-
Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM
-
Ofei F, Hurel S, Newkirk J, Sopwith M, Taylor R (1996) Effects of an engineered human anti-TNF-alpha antibody (CDP571) on insulin sensitivity and glycemic control in patients with NIDDM. Diabetes 45:881-885.
-
(1996)
Diabetes
, vol.45
, pp. 881-885
-
-
Ofei, F.1
Hurel, S.2
Newkirk, J.3
Sopwith, M.4
Taylor, R.5
-
48
-
-
4944258755
-
Improvement of insulin sensitivity in insulin resistant subjects during prolonged treatment with the anti-TNF-alpha antibody infliximab
-
Yazdani-Biuki B, Stelzl H, Brezinschek HP et al (2004) Improvement of insulin sensitivity in insulin resistant subjects during prolonged treatment with the anti-TNF-alpha antibody infliximab. Eur J Clin Invest 34:641-642.
-
(2004)
Eur J Clin Invest
, vol.34
, pp. 641-642
-
-
Yazdani-Biuki, B.1
Stelzl, H.2
Brezinschek, H.P.3
|