메뉴 건너뛰기




Volumn 24, Issue 2, 2006, Pages 179-189

TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 23; INTERLEUKIN 6; PROTEIN; PROTEIN HLX; SMAD7 PROTEIN; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 9; TRANSCRIPTION FACTOR GATA 3; TRANSCRIPTION FACTOR T BET; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; INTERLEUKIN 1 RECEPTOR; MEMBRANE PROTEIN; TGFB1 PROTEIN, MOUSE; TIRAP PROTEIN, MOUSE;

EID: 32244442562     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.immuni.2006.01.001     Document Type: Article
Times cited : (3179)

References (70)
  • 1
    • 0037449737 scopus 로고    scopus 로고
    • Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
    • S. Aggarwal, N. Ghilardi, M.H. Xie, F.J. de Sauvage, and A.L. Gurney Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17 J. Biol. Chem. 278 2003 1910 1914
    • (2003) J. Biol. Chem. , vol.278 , pp. 1910-1914
    • Aggarwal, S.1    Ghilardi, N.2    Xie, M.H.3    De Sauvage, F.J.4    Gurney, A.L.5
  • 2
    • 0025017687 scopus 로고
    • Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor beta
    • J.B. Allen, C.L. Manthey, A.R. Hand, K. Ohura, L. Ellingsworth, and S.M. Wahl Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor beta J. Exp. Med. 171 1990 231 247
    • (1990) J. Exp. Med. , vol.171 , pp. 231-247
    • Allen, J.B.1    Manthey, C.L.2    Hand, A.R.3    Ohura, K.4    Ellingsworth, L.5    Wahl, S.M.6
  • 3
    • 0036839102 scopus 로고    scopus 로고
    • Homeostasis of peripheral CD4(+) T cells: IL-2Ralpha and IL-2 shape a population of regulatory cells that controls CD4(+) T cell numbers
    • A.R. Almeida, N. Legrand, M. Papiernik, and A.A. Freitas Homeostasis of peripheral CD4(+) T cells: IL-2Ralpha and IL-2 shape a population of regulatory cells that controls CD4(+) T cell numbers J. Immunol. 169 2002 4850 4860
    • (2002) J. Immunol. , vol.169 , pp. 4850-4860
    • Almeida, A.R.1    Legrand, N.2    Papiernik, M.3    Freitas, A.A.4
  • 5
    • 0034176747 scopus 로고    scopus 로고
    • Regulatory CD4 T cells control the size of the peripheral activated/memory CD4 T cell compartment
    • O. Annacker, O. Burlen-Defranoux, R. Pimenta-Araujo, A. Cumano, and A. Bandeira Regulatory CD4 T cells control the size of the peripheral activated/memory CD4 T cell compartment J. Immunol. 164 2000 3573 3580
    • (2000) J. Immunol. , vol.164 , pp. 3573-3580
    • Annacker, O.1    Burlen-Defranoux, O.2    Pimenta-Araujo, R.3    Cumano, A.4    Bandeira, A.5
  • 7
    • 0141796312 scopus 로고    scopus 로고
    • TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
    • M. Belghith, J.A. Bluestone, S. Barriot, J. Megret, J.F. Bach, and L. Chatenoud TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes Nat. Med. 9 2003 1202 1208
    • (2003) Nat. Med. , vol.9 , pp. 1202-1208
    • Belghith, M.1    Bluestone, J.A.2    Barriot, S.3    Megret, J.4    Bach, J.F.5    Chatenoud, L.6
  • 8
    • 3142724732 scopus 로고    scopus 로고
    • Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis
    • E. Bettelli, B. Sullivan, S.J. Szabo, R.A. Sobel, L.H. Glimcher, and V.K. Kuchroo Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis J. Exp. Med. 200 2004 79 87
    • (2004) J. Exp. Med. , vol.200 , pp. 79-87
    • Bettelli, E.1    Sullivan, B.2    Szabo, S.J.3    Sobel, R.A.4    Glimcher, L.H.5    Kuchroo, V.K.6
  • 9
    • 0037867066 scopus 로고    scopus 로고
    • Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation
    • C.H. Chen, C. Seguin-Devaux, N.A. Burke, T.B. Oriss, S.C. Watkins, N. Clipstone, and A. Ray Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation J. Exp. Med. 197 2003 1689 1699
    • (2003) J. Exp. Med. , vol.197 , pp. 1689-1699
    • Chen, C.H.1    Seguin-Devaux, C.2    Burke, N.A.3    Oriss, T.B.4    Watkins, S.C.5    Clipstone, N.6    Ray, A.7
  • 10
    • 0037592950 scopus 로고    scopus 로고
    • Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop
    • Y. Chen, P. Thai, Y.H. Zhao, Y.S. Ho, M.M. DeSouza, and R. Wu Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop J. Biol. Chem. 278 2003 17036 17043
    • (2003) J. Biol. Chem. , vol.278 , pp. 17036-17043
    • Chen, Y.1    Thai, P.2    Zhao, Y.H.3    Ho, Y.S.4    Desouza, M.M.5    Wu, R.6
  • 12
    • 4644369302 scopus 로고    scopus 로고
    • Interleukin-2 is essential for CD4+CD25+ regulatory T cell function
    • M. de la Rosa, S. Rutz, H. Dorninger, and A. Scheffold Interleukin-2 is essential for CD4+CD25+ regulatory T cell function Eur. J. Immunol. 34 2004 2480 2488
    • (2004) Eur. J. Immunol. , vol.34 , pp. 2480-2488
    • De La Rosa, M.1    Rutz, S.2    Dorninger, H.3    Scheffold, A.4
  • 13
    • 0031852288 scopus 로고    scopus 로고
    • IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
    • H.P. Eugster, K. Frei, M. Kopf, H. Lassmann, and A. Fontana IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis Eur. J. Immunol. 28 1998 2178 2187
    • (1998) Eur. J. Immunol. , vol.28 , pp. 2178-2187
    • Eugster, H.P.1    Frei, K.2    Kopf, M.3    Lassmann, H.4    Fontana, A.5
  • 15
    • 0025727898 scopus 로고
    • Transforming growth factor beta 1 (TGF-beta 1) induced neutrophil recruitment to synovial tissues: Implications for TGF-beta-driven synovial inflammation and hyperplasia
    • R.A. Fava, N.J. Olsen, A.E. Postlethwaite, K.N. Broadley, J.M. Davidson, L.B. Nanney, C. Lucas, and A.S. Townes Transforming growth factor beta 1 (TGF-beta 1) induced neutrophil recruitment to synovial tissues: implications for TGF-beta-driven synovial inflammation and hyperplasia J. Exp. Med. 173 1991 1121 1132
    • (1991) J. Exp. Med. , vol.173 , pp. 1121-1132
    • Fava, R.A.1    Olsen, N.J.2    Postlethwaite, A.E.3    Broadley, K.N.4    Davidson, J.M.5    Nanney, L.B.6    Lucas, C.7    Townes, A.S.8
  • 17
    • 16844363097 scopus 로고    scopus 로고
    • A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3
    • J.D. Fontenot, and A.Y. Rudensky A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3 Nat. Immunol. 6 2005 331 337
    • (2005) Nat. Immunol. , vol.6 , pp. 331-337
    • Fontenot, J.D.1    Rudensky, A.Y.2
  • 20
    • 0034131557 scopus 로고    scopus 로고
    • Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
    • L. Gorelik, and R.A. Flavell Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease Immunity 12 2000 171 181
    • (2000) Immunity , vol.12 , pp. 171-181
    • Gorelik, L.1    Flavell, R.A.2
  • 21
    • 0036372440 scopus 로고    scopus 로고
    • Transforming growth factor-beta in T-cell biology
    • L. Gorelik, and R.A. Flavell Transforming growth factor-beta in T-cell biology Nat. Rev. Immunol. 2 2002 46 53
    • (2002) Nat. Rev. Immunol. , vol.2 , pp. 46-53
    • Gorelik, L.1    Flavell, R.A.2
  • 22
    • 0034327176 scopus 로고    scopus 로고
    • Cutting edge: TGF-beta inhibits Th type 2 development through inhibition of GATA-3 expression
    • L. Gorelik, P.E. Fields, and R.A. Flavell Cutting edge: TGF-beta inhibits Th type 2 development through inhibition of GATA-3 expression J. Immunol. 165 2000 4773 4777
    • (2000) J. Immunol. , vol.165 , pp. 4773-4777
    • Gorelik, L.1    Fields, P.E.2    Flavell, R.A.3
  • 23
    • 0037013930 scopus 로고    scopus 로고
    • Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation
    • L. Gorelik, S. Constant, and R.A. Flavell Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation J. Exp. Med. 195 2002 1499 1505
    • (2002) J. Exp. Med. , vol.195 , pp. 1499-1505
    • Gorelik, L.1    Constant, S.2    Flavell, R.A.3
  • 24
    • 27544490377 scopus 로고    scopus 로고
    • Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
    • L.E. Harrington, R.D. Hatton, P.R. Mangan, H. Turner, T.L. Murphy, K.M. Murphy, and C.T. Weaver Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages Nat. Immunol. 6 2005 1123 1132
    • (2005) Nat. Immunol. , vol.6 , pp. 1123-1132
    • Harrington, L.E.1    Hatton, R.D.2    Mangan, P.R.3    Turner, H.4    Murphy, T.L.5    Murphy, K.M.6    Weaver, C.T.7
  • 27
    • 0033623339 scopus 로고    scopus 로고
    • TGF-beta1 down-regulates Th2 development and results in decreased IL-4-induced STAT6 activation and GATA-3 expression
    • V.L. Heath, E.E. Murphy, C. Crain, M.G. Tomlinson, and A. O'Garra TGF-beta1 down-regulates Th2 development and results in decreased IL-4-induced STAT6 activation and GATA-3 expression Eur. J. Immunol. 30 2000 2639 2649
    • (2000) Eur. J. Immunol. , vol.30 , pp. 2639-2649
    • Heath, V.L.1    Murphy, E.E.2    Crain, C.3    Tomlinson, M.G.4    O'Garra, A.5
  • 28
    • 0035339861 scopus 로고    scopus 로고
    • Endotoxin-induced maturation of MyD88-deficient dendritic cells
    • T. Kaisho, O. Takeuchi, T. Kawai, K. Hoshino, and S. Akira Endotoxin-induced maturation of MyD88-deficient dendritic cells J. Immunol. 166 2001 5688 5694
    • (2001) J. Immunol. , vol.166 , pp. 5688-5694
    • Kaisho, T.1    Takeuchi, O.2    Kawai, T.3    Hoshino, K.4    Akira, S.5
  • 29
    • 0034128634 scopus 로고    scopus 로고
    • Claudins regulate the intestinal barrier in response to immune mediators
    • T. Kinugasa, T. Sakaguchi, X. Gu, and H.C. Reinecker Claudins regulate the intestinal barrier in response to immune mediators Gastroenterology 118 2000 1001 1011
    • (2000) Gastroenterology , vol.118 , pp. 1001-1011
    • Kinugasa, T.1    Sakaguchi, T.2    Gu, X.3    Reinecker, H.C.4
  • 30
    • 5644277476 scopus 로고    scopus 로고
    • Interleukin-17 family members and inflammation
    • J.K. Kolls, and A. Linden Interleukin-17 family members and inflammation Immunity 21 2004 467 476
    • (2004) Immunity , vol.21 , pp. 467-476
    • Kolls, J.K.1    Linden, A.2
  • 33
    • 24644441010 scopus 로고    scopus 로고
    • TGF-beta signaling in T cells: Roles in lymphoid and epithelial neoplasia
    • J.J. Letterio TGF-beta signaling in T cells: roles in lymphoid and epithelial neoplasia Oncogene 24 2005 5701 5712
    • (2005) Oncogene , vol.24 , pp. 5701-5712
    • Letterio, J.J.1
  • 34
    • 0031944290 scopus 로고    scopus 로고
    • Regulation of immune responses by TGF-beta
    • J.J. Letterio, and A.B. Roberts Regulation of immune responses by TGF-beta Annu. Rev. Immunol. 16 1998 137 161
    • (1998) Annu. Rev. Immunol. , vol.16 , pp. 137-161
    • Letterio, J.J.1    Roberts, A.B.2
  • 35
    • 18644381773 scopus 로고    scopus 로고
    • TGF-beta 1 uses distinct mechanisms to inhibit IFN-gamma expression in CD4+ T cells at priming and at recall: Differential involvement of Stat4 and T-bet
    • J.T. Lin, S.L. Martin, L. Xia, and J.D. Gorham TGF-beta 1 uses distinct mechanisms to inhibit IFN-gamma expression in CD4+ T cells at priming and at recall: differential involvement of Stat4 and T-bet J. Immunol. 174 2005 5950 5958
    • (2005) J. Immunol. , vol.174 , pp. 5950-5958
    • Lin, J.T.1    Martin, S.L.2    Xia, L.3    Gorham, J.D.4
  • 37
  • 38
    • 0035554676 scopus 로고    scopus 로고
    • Regulatory T cells in the control of immune pathology
    • K.J. Maloy, and F. Powrie Regulatory T cells in the control of immune pathology Nat. Immunol. 2 2001 816 822
    • (2001) Nat. Immunol. , vol.2 , pp. 816-822
    • Maloy, K.J.1    Powrie, F.2
  • 39
    • 0034691541 scopus 로고    scopus 로고
    • TGF-beta 1 differentially regulates IL-2 expression and [3H]-thymidine incorporation in CD3 epsilon mAb- and CD28 mAb-activated splenocytes and thymocytes
    • S.C. McKarns, and N.E. Kaminski TGF-beta 1 differentially regulates IL-2 expression and [3H]-thymidine incorporation in CD3 epsilon mAb- and CD28 mAb-activated splenocytes and thymocytes Immunopharmacology 48 2000 101 115
    • (2000) Immunopharmacology , vol.48 , pp. 101-115
    • McKarns, S.C.1    Kaminski, N.E.2
  • 43
    • 0036754255 scopus 로고    scopus 로고
    • Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses
    • S. Nakae, Y. Komiyama, A. Nambu, K. Sudo, M. Iwase, I. Homma, K. Sekikawa, M. Asano, and Y. Iwakura Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses Immunity 17 2002 375 387
    • (2002) Immunity , vol.17 , pp. 375-387
    • Nakae, S.1    Komiyama, Y.2    Nambu, A.3    Sudo, K.4    Iwase, M.5    Homma, I.6    Sekikawa, K.7    Asano, M.8    Iwakura, Y.9
  • 44
    • 0035801335 scopus 로고    scopus 로고
    • Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
    • K. Nakamura, A. Kitani, and W. Strober Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta J. Exp. Med. 194 2001 629 644
    • (2001) J. Exp. Med. , vol.194 , pp. 629-644
    • Nakamura, K.1    Kitani, A.2    Strober, W.3
  • 46
    • 85047692430 scopus 로고    scopus 로고
    • IL-10-producing and naturally occurring CD4+ Tregs: Limiting collateral damage
    • A. O'Garra, P.L. Vieira, P. Vieira, and A.E. Goldfeld IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage J. Clin. Invest. 114 2004 1372 1378
    • (2004) J. Clin. Invest. , vol.114 , pp. 1372-1378
    • O'Garra, A.1    Vieira, P.L.2    Vieira, P.3    Goldfeld, A.E.4
  • 47
    • 0842324613 scopus 로고    scopus 로고
    • Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice
    • A. Ogawa, A. Andoh, Y. Araki, T. Bamba, and Y. Fujiyama Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice Clin. Immunol. 110 2004 55 62
    • (2004) Clin. Immunol. , vol.110 , pp. 55-62
    • Ogawa, A.1    Andoh, A.2    Araki, Y.3    Bamba, T.4    Fujiyama, Y.5
  • 49
    • 0031920882 scopus 로고    scopus 로고
    • IL-6-deficient mice are resistant to the induction of experimental autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein
    • Y. Okuda, S. Sakoda, C.C. Bernard, H. Fujimura, Y. Saeki, T. Kishimoto, and T. Yanagihara IL-6-deficient mice are resistant to the induction of experimental autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein Int. Immunol. 10 1998 703 708
    • (1998) Int. Immunol. , vol.10 , pp. 703-708
    • Okuda, Y.1    Sakoda, S.2    Bernard, C.C.3    Fujimura, H.4    Saeki, Y.5    Kishimoto, T.6    Yanagihara, T.7
  • 50
    • 0033638507 scopus 로고    scopus 로고
    • Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
    • B. Oppmann, R. Lesley, B. Blom, J.C. Timans, Y. Xu, B. Hunte, F. Vega, N. Yu, J. Wang, and K. Singh Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12 Immunity 13 2000 715 725
    • (2000) Immunity , vol.13 , pp. 715-725
    • Oppmann, B.1    Lesley, R.2    Blom, B.3    Timans, J.C.4    Xu, Y.5    Hunte, B.6    Vega, F.7    Yu, N.8    Wang, J.9    Singh, K.10
  • 52
    • 0037436119 scopus 로고    scopus 로고
    • Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
    • C. Pasare, and R. Medzhitov Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells Science 299 2003 1033 1036
    • (2003) Science , vol.299 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 53
    • 0037099613 scopus 로고    scopus 로고
    • CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness
    • C.A. Piccirillo, J.J. Letterio, A.M. Thornton, R.S. McHugh, M. Mamura, H. Mizuhara, and E.M. Shevach CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness J. Exp. Med. 196 2002 237 246
    • (2002) J. Exp. Med. , vol.196 , pp. 237-246
    • Piccirillo, C.A.1    Letterio, J.J.2    Thornton, A.M.3    McHugh, R.S.4    Mamura, M.5    Mizuhara, H.6    Shevach, E.M.7
  • 54
    • 0029085294 scopus 로고
    • T cells in inflammatory bowel disease: Protective and pathogenic roles
    • F. Powrie T cells in inflammatory bowel disease: protective and pathogenic roles Immunity 3 1995 171 174
    • (1995) Immunity , vol.3 , pp. 171-174
    • Powrie, F.1
  • 55
    • 0742272509 scopus 로고    scopus 로고
    • Toll-like receptors and dendritic cells: For whom the bug tolls
    • C. Reis e Sousa Toll-like receptors and dendritic cells: for whom the bug tolls Semin. Immunol. 16 2004 27 34
    • (2004) Semin. Immunol. , vol.16 , pp. 27-34
    • Reis, E.1    Sousa, C.2
  • 56
    • 17044377812 scopus 로고    scopus 로고
    • IL-6 increases primed cell expansion and survival
    • I. Rochman, W.E. Paul, and S.Z. Ben-Sasson IL-6 increases primed cell expansion and survival J. Immunol. 174 2005 4761 4767
    • (2005) J. Immunol. , vol.174 , pp. 4761-4767
    • Rochman, I.1    Paul, W.E.2    Ben-Sasson, S.Z.3
  • 57
    • 16844365788 scopus 로고    scopus 로고
    • Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
    • S. Sakaguchi Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self Nat. Immunol. 6 2005 345 352
    • (2005) Nat. Immunol. , vol.6 , pp. 345-352
    • Sakaguchi, S.1
  • 58
    • 0038682002 scopus 로고    scopus 로고
    • Mechanisms of TGF-beta signaling from cell membrane to the nucleus
    • Y. Shi, and J. Massague Mechanisms of TGF-beta signaling from cell membrane to the nucleus Cell 113 2003 685 700
    • (2003) Cell , vol.113 , pp. 685-700
    • Shi, Y.1    Massague, J.2
  • 61
    • 0028144631 scopus 로고
    • Functional recognition of in vivo processed self antigen
    • B. Stockinger, and B. Hausmann Functional recognition of in vivo processed self antigen Int. Immunol. 6 1994 247 254
    • (1994) Int. Immunol. , vol.6 , pp. 247-254
    • Stockinger, B.1    Hausmann, B.2
  • 62
    • 8044250881 scopus 로고    scopus 로고
    • Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells
    • S.J. Szabo, A.S. Dighe, U. Gubler, and K.M. Murphy Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells J. Exp. Med. 185 1997 817 824
    • (1997) J. Exp. Med. , vol.185 , pp. 817-824
    • Szabo, S.J.1    Dighe, A.S.2    Gubler, U.3    Murphy, K.M.4
  • 63
  • 64
    • 0030890718 scopus 로고    scopus 로고
    • Gp130 and the interleukin-6 family of cytokines
    • T. Taga, and T. Kishimoto Gp130 and the interleukin-6 family of cytokines Annu. Rev. Immunol. 15 1997 797 819
    • (1997) Annu. Rev. Immunol. , vol.15 , pp. 797-819
    • Taga, T.1    Kishimoto, T.2
  • 65
    • 0031821875 scopus 로고    scopus 로고
    • CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
    • A.M. Thornton, and E.M. Shevach CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production J. Exp. Med. 188 1998 287 296
    • (1998) J. Exp. Med. , vol.188 , pp. 287-296
    • Thornton, A.M.1    Shevach, E.M.2
  • 66
    • 0033602101 scopus 로고    scopus 로고
    • Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway
    • L. Ulloa, J. Doody, and J. Massague Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway Nature 397 1999 710 713
    • (1999) Nature , vol.397 , pp. 710-713
    • Ulloa, L.1    Doody, J.2    Massague, J.3
  • 67
    • 14744284737 scopus 로고    scopus 로고
    • IL-23 up-regulates IL-10 and induces IL-17 synthesis by polyclonally activated naive T cells in human
    • S. Vanden Eijnden, S. Goriely, D. De Wit, F. Willems, and M. Goldman IL-23 up-regulates IL-10 and induces IL-17 synthesis by polyclonally activated naive T cells in human Eur. J. Immunol. 35 2005 469 475
    • (2005) Eur. J. Immunol. , vol.35 , pp. 469-475
    • Vanden Eijnden, S.1    Goriely, S.2    De Wit, D.3    Willems, F.4    Goldman, M.5
  • 68
    • 0028152937 scopus 로고
    • Transforming growth factor beta: The good, the bad, and the ugly
    • S.M. Wahl Transforming growth factor beta: the good, the bad, and the ugly J. Exp. Med. 180 1994 1587 1590
    • (1994) J. Exp. Med. , vol.180 , pp. 1587-1590
    • Wahl, S.M.1
  • 69
    • 0027392551 scopus 로고
    • Reversal of acute and chronic synovial inflammation by anti-transforming growth factor beta
    • S.M. Wahl, J.B. Allen, G.L. Costa, H.L. Wong, and J.R. Dasch Reversal of acute and chronic synovial inflammation by anti-transforming growth factor beta J. Exp. Med. 177 1993 225 230
    • (1993) J. Exp. Med. , vol.177 , pp. 225-230
    • Wahl, S.M.1    Allen, J.B.2    Costa, G.L.3    Wong, H.L.4    Dasch, J.R.5
  • 70
    • 0030810155 scopus 로고    scopus 로고
    • The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
    • W. Zheng, and R.A. Flavell The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells Cell 89 1997 587 596
    • (1997) Cell , vol.89 , pp. 587-596
    • Zheng, W.1    Flavell, R.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.