-
1
-
-
0037449737
-
Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17
-
S. Aggarwal, N. Ghilardi, M.H. Xie, F.J. de Sauvage, and A.L. Gurney Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17 J. Biol. Chem. 278 2003 1910 1914
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 1910-1914
-
-
Aggarwal, S.1
Ghilardi, N.2
Xie, M.H.3
De Sauvage, F.J.4
Gurney, A.L.5
-
2
-
-
0025017687
-
Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor beta
-
J.B. Allen, C.L. Manthey, A.R. Hand, K. Ohura, L. Ellingsworth, and S.M. Wahl Rapid onset synovial inflammation and hyperplasia induced by transforming growth factor beta J. Exp. Med. 171 1990 231 247
-
(1990)
J. Exp. Med.
, vol.171
, pp. 231-247
-
-
Allen, J.B.1
Manthey, C.L.2
Hand, A.R.3
Ohura, K.4
Ellingsworth, L.5
Wahl, S.M.6
-
3
-
-
0036839102
-
Homeostasis of peripheral CD4(+) T cells: IL-2Ralpha and IL-2 shape a population of regulatory cells that controls CD4(+) T cell numbers
-
A.R. Almeida, N. Legrand, M. Papiernik, and A.A. Freitas Homeostasis of peripheral CD4(+) T cells: IL-2Ralpha and IL-2 shape a population of regulatory cells that controls CD4(+) T cell numbers J. Immunol. 169 2002 4850 4860
-
(2002)
J. Immunol.
, vol.169
, pp. 4850-4860
-
-
Almeida, A.R.1
Legrand, N.2
Papiernik, M.3
Freitas, A.A.4
-
4
-
-
0032536542
-
Interleukin 6 is required for the development of collagen-induced arthritis
-
T. Alonzi, E. Fattori, D. Lazzaro, P. Costa, L. Probert, G. Kollias, F. De Benedetti, V. Poli, and G. Ciliberto Interleukin 6 is required for the development of collagen-induced arthritis J. Exp. Med. 187 1998 461 468
-
(1998)
J. Exp. Med.
, vol.187
, pp. 461-468
-
-
Alonzi, T.1
Fattori, E.2
Lazzaro, D.3
Costa, P.4
Probert, L.5
Kollias, G.6
De Benedetti, F.7
Poli, V.8
Ciliberto, G.9
-
5
-
-
0034176747
-
Regulatory CD4 T cells control the size of the peripheral activated/memory CD4 T cell compartment
-
O. Annacker, O. Burlen-Defranoux, R. Pimenta-Araujo, A. Cumano, and A. Bandeira Regulatory CD4 T cells control the size of the peripheral activated/memory CD4 T cell compartment J. Immunol. 164 2000 3573 3580
-
(2000)
J. Immunol.
, vol.164
, pp. 3573-3580
-
-
Annacker, O.1
Burlen-Defranoux, O.2
Pimenta-Araujo, R.3
Cumano, A.4
Bandeira, A.5
-
6
-
-
14944386649
-
CD25+ CD4+ T cells compete with naive CD4+ T cells for IL-2 and exploit it for the induction of IL-10 production
-
T. Barthlott, H. Moncrieffe, M. Veldhoen, C.J. Atkins, J. Christensen, A. O'Garra, and B. Stockinger CD25+ CD4+ T cells compete with naive CD4+ T cells for IL-2 and exploit it for the induction of IL-10 production Int. Immunol. 17 2005 279 288
-
(2005)
Int. Immunol.
, vol.17
, pp. 279-288
-
-
Barthlott, T.1
Moncrieffe, H.2
Veldhoen, M.3
Atkins, C.J.4
Christensen, J.5
O'Garra, A.6
Stockinger, B.7
-
7
-
-
0141796312
-
TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes
-
M. Belghith, J.A. Bluestone, S. Barriot, J. Megret, J.F. Bach, and L. Chatenoud TGF-beta-dependent mechanisms mediate restoration of self-tolerance induced by antibodies to CD3 in overt autoimmune diabetes Nat. Med. 9 2003 1202 1208
-
(2003)
Nat. Med.
, vol.9
, pp. 1202-1208
-
-
Belghith, M.1
Bluestone, J.A.2
Barriot, S.3
Megret, J.4
Bach, J.F.5
Chatenoud, L.6
-
8
-
-
3142724732
-
Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis
-
E. Bettelli, B. Sullivan, S.J. Szabo, R.A. Sobel, L.H. Glimcher, and V.K. Kuchroo Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis J. Exp. Med. 200 2004 79 87
-
(2004)
J. Exp. Med.
, vol.200
, pp. 79-87
-
-
Bettelli, E.1
Sullivan, B.2
Szabo, S.J.3
Sobel, R.A.4
Glimcher, L.H.5
Kuchroo, V.K.6
-
9
-
-
0037867066
-
Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation
-
C.H. Chen, C. Seguin-Devaux, N.A. Burke, T.B. Oriss, S.C. Watkins, N. Clipstone, and A. Ray Transforming growth factor beta blocks Tec kinase phosphorylation, Ca2+ influx, and NFATc translocation causing inhibition of T cell differentiation J. Exp. Med. 197 2003 1689 1699
-
(2003)
J. Exp. Med.
, vol.197
, pp. 1689-1699
-
-
Chen, C.H.1
Seguin-Devaux, C.2
Burke, N.A.3
Oriss, T.B.4
Watkins, S.C.5
Clipstone, N.6
Ray, A.7
-
10
-
-
0037592950
-
Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop
-
Y. Chen, P. Thai, Y.H. Zhao, Y.S. Ho, M.M. DeSouza, and R. Wu Stimulation of airway mucin gene expression by interleukin (IL)-17 through IL-6 paracrine/autocrine loop J. Biol. Chem. 278 2003 17036 17043
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17036-17043
-
-
Chen, Y.1
Thai, P.2
Zhao, Y.H.3
Ho, Y.S.4
Desouza, M.M.5
Wu, R.6
-
11
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
D.J. Cua, J. Sherlock, Y. Chen, C.A. Murphy, B. Joyce, B. Seymour, L. Lucian, W. To, S. Kwan, and T. Churakova Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain Nature 421 2003 744 748
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
Murphy, C.A.4
Joyce, B.5
Seymour, B.6
Lucian, L.7
To, W.8
Kwan, S.9
Churakova, T.10
-
12
-
-
4644369302
-
Interleukin-2 is essential for CD4+CD25+ regulatory T cell function
-
M. de la Rosa, S. Rutz, H. Dorninger, and A. Scheffold Interleukin-2 is essential for CD4+CD25+ regulatory T cell function Eur. J. Immunol. 34 2004 2480 2488
-
(2004)
Eur. J. Immunol.
, vol.34
, pp. 2480-2488
-
-
De La Rosa, M.1
Rutz, S.2
Dorninger, H.3
Scheffold, A.4
-
13
-
-
0031852288
-
IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
-
H.P. Eugster, K. Frei, M. Kopf, H. Lassmann, and A. Fontana IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis Eur. J. Immunol. 28 1998 2178 2187
-
(1998)
Eur. J. Immunol.
, vol.28
, pp. 2178-2187
-
-
Eugster, H.P.1
Frei, K.2
Kopf, M.3
Lassmann, H.4
Fontana, A.5
-
14
-
-
15444363794
-
T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells
-
L. Fahlen, S. Read, L. Gorelik, S.D. Hurst, R.L. Coffman, R.A. Flavell, and F. Powrie T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells J. Exp. Med. 201 2005 737 746
-
(2005)
J. Exp. Med.
, vol.201
, pp. 737-746
-
-
Fahlen, L.1
Read, S.2
Gorelik, L.3
Hurst, S.D.4
Coffman, R.L.5
Flavell, R.A.6
Powrie, F.7
-
15
-
-
0025727898
-
Transforming growth factor beta 1 (TGF-beta 1) induced neutrophil recruitment to synovial tissues: Implications for TGF-beta-driven synovial inflammation and hyperplasia
-
R.A. Fava, N.J. Olsen, A.E. Postlethwaite, K.N. Broadley, J.M. Davidson, L.B. Nanney, C. Lucas, and A.S. Townes Transforming growth factor beta 1 (TGF-beta 1) induced neutrophil recruitment to synovial tissues: implications for TGF-beta-driven synovial inflammation and hyperplasia J. Exp. Med. 173 1991 1121 1132
-
(1991)
J. Exp. Med.
, vol.173
, pp. 1121-1132
-
-
Fava, R.A.1
Olsen, N.J.2
Postlethwaite, A.E.3
Broadley, K.N.4
Davidson, J.M.5
Nanney, L.B.6
Lucas, C.7
Townes, A.S.8
-
17
-
-
16844363097
-
A well adapted regulatory contrivance: Regulatory T cell development and the forkhead family transcription factor Foxp3
-
J.D. Fontenot, and A.Y. Rudensky A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3 Nat. Immunol. 6 2005 331 337
-
(2005)
Nat. Immunol.
, vol.6
, pp. 331-337
-
-
Fontenot, J.D.1
Rudensky, A.Y.2
-
18
-
-
15244354286
-
Regulatory T cell lineage specification by the forkhead transcription factor foxp3
-
J.D. Fontenot, J.P. Rasmussen, L.M. Williams, J.L. Dooley, A.G. Farr, and A.Y. Rudensky Regulatory T cell lineage specification by the forkhead transcription factor foxp3 Immunity 22 2005 329 341
-
(2005)
Immunity
, vol.22
, pp. 329-341
-
-
Fontenot, J.D.1
Rasmussen, J.P.2
Williams, L.M.3
Dooley, J.L.4
Farr, A.G.5
Rudensky, A.Y.6
-
19
-
-
0031803464
-
Interleukin-17
-
F. Fossiez, J. Banchereau, R. Murray, C. Van Kooten, P. Garrone, and S. Lebecque Interleukin-17 Int. Rev. Immunol. 16 1998 541 551
-
(1998)
Int. Rev. Immunol.
, vol.16
, pp. 541-551
-
-
Fossiez, F.1
Banchereau, J.2
Murray, R.3
Van Kooten, C.4
Garrone, P.5
Lebecque, S.6
-
20
-
-
0034131557
-
Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease
-
L. Gorelik, and R.A. Flavell Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease Immunity 12 2000 171 181
-
(2000)
Immunity
, vol.12
, pp. 171-181
-
-
Gorelik, L.1
Flavell, R.A.2
-
21
-
-
0036372440
-
Transforming growth factor-beta in T-cell biology
-
L. Gorelik, and R.A. Flavell Transforming growth factor-beta in T-cell biology Nat. Rev. Immunol. 2 2002 46 53
-
(2002)
Nat. Rev. Immunol.
, vol.2
, pp. 46-53
-
-
Gorelik, L.1
Flavell, R.A.2
-
22
-
-
0034327176
-
Cutting edge: TGF-beta inhibits Th type 2 development through inhibition of GATA-3 expression
-
L. Gorelik, P.E. Fields, and R.A. Flavell Cutting edge: TGF-beta inhibits Th type 2 development through inhibition of GATA-3 expression J. Immunol. 165 2000 4773 4777
-
(2000)
J. Immunol.
, vol.165
, pp. 4773-4777
-
-
Gorelik, L.1
Fields, P.E.2
Flavell, R.A.3
-
23
-
-
0037013930
-
Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation
-
L. Gorelik, S. Constant, and R.A. Flavell Mechanism of transforming growth factor beta-induced inhibition of T helper type 1 differentiation J. Exp. Med. 195 2002 1499 1505
-
(2002)
J. Exp. Med.
, vol.195
, pp. 1499-1505
-
-
Gorelik, L.1
Constant, S.2
Flavell, R.A.3
-
24
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
L.E. Harrington, R.D. Hatton, P.R. Mangan, H. Turner, T.L. Murphy, K.M. Murphy, and C.T. Weaver Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages Nat. Immunol. 6 2005 1123 1132
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
Weaver, C.T.7
-
25
-
-
4344590199
-
Distinct contribution of IL-6, TNF-alpha, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice
-
H. Hata, N. Sakaguchi, H. Yoshitomi, Y. Iwakura, K. Sekikawa, Y. Azuma, C. Kanai, E. Moriizumi, T. Nomura, T. Nakamura, and S. Sakaguchi Distinct contribution of IL-6, TNF-alpha, IL-1, and IL-10 to T cell-mediated spontaneous autoimmune arthritis in mice J. Clin. Invest. 114 2004 582 588
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 582-588
-
-
Hata, H.1
Sakaguchi, N.2
Yoshitomi, H.3
Iwakura, Y.4
Sekikawa, K.5
Azuma, Y.6
Kanai, C.7
Moriizumi, E.8
Nomura, T.9
Nakamura, T.10
Sakaguchi, S.11
-
26
-
-
0031587828
-
The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling
-
H. Hayashi, S. Abdollah, Y. Qiu, J. Cai, Y.Y. Xu, B.W. Grinnell, M.A. Richardson, J.N. Topper, M.A. Gimbrone Jr., J.L. Wrana, and D. Falb The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling Cell 89 1997 1165 1173
-
(1997)
Cell
, vol.89
, pp. 1165-1173
-
-
Hayashi, H.1
Abdollah, S.2
Qiu, Y.3
Cai, J.4
Xu, Y.Y.5
Grinnell, B.W.6
Richardson, M.A.7
Topper, J.N.8
Gimbrone Jr., M.A.9
Wrana, J.L.10
Falb, D.11
-
27
-
-
0033623339
-
TGF-beta1 down-regulates Th2 development and results in decreased IL-4-induced STAT6 activation and GATA-3 expression
-
V.L. Heath, E.E. Murphy, C. Crain, M.G. Tomlinson, and A. O'Garra TGF-beta1 down-regulates Th2 development and results in decreased IL-4-induced STAT6 activation and GATA-3 expression Eur. J. Immunol. 30 2000 2639 2649
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 2639-2649
-
-
Heath, V.L.1
Murphy, E.E.2
Crain, C.3
Tomlinson, M.G.4
O'Garra, A.5
-
28
-
-
0035339861
-
Endotoxin-induced maturation of MyD88-deficient dendritic cells
-
T. Kaisho, O. Takeuchi, T. Kawai, K. Hoshino, and S. Akira Endotoxin-induced maturation of MyD88-deficient dendritic cells J. Immunol. 166 2001 5688 5694
-
(2001)
J. Immunol.
, vol.166
, pp. 5688-5694
-
-
Kaisho, T.1
Takeuchi, O.2
Kawai, T.3
Hoshino, K.4
Akira, S.5
-
29
-
-
0034128634
-
Claudins regulate the intestinal barrier in response to immune mediators
-
T. Kinugasa, T. Sakaguchi, X. Gu, and H.C. Reinecker Claudins regulate the intestinal barrier in response to immune mediators Gastroenterology 118 2000 1001 1011
-
(2000)
Gastroenterology
, vol.118
, pp. 1001-1011
-
-
Kinugasa, T.1
Sakaguchi, T.2
Gu, X.3
Reinecker, H.C.4
-
30
-
-
5644277476
-
Interleukin-17 family members and inflammation
-
J.K. Kolls, and A. Linden Interleukin-17 family members and inflammation Immunity 21 2004 467 476
-
(2004)
Immunity
, vol.21
, pp. 467-476
-
-
Kolls, J.K.1
Linden, A.2
-
31
-
-
0027531528
-
Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death
-
A.B. Kulkarni, C.G. Huh, D. Becker, A. Geiser, M. Lyght, K.C. Flanders, A.B. Roberts, M.B. Sporn, J.M. Ward, and S. Karlsson Transforming growth factor beta 1 null mutation in mice causes excessive inflammatory response and early death Proc. Natl. Acad. Sci. USA 90 1993 770 774
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 770-774
-
-
Kulkarni, A.B.1
Huh, C.G.2
Becker, D.3
Geiser, A.4
Lyght, M.5
Flanders, K.C.6
Roberts, A.B.7
Sporn, M.B.8
Ward, J.M.9
Karlsson, S.10
-
32
-
-
13244283212
-
IL-23 drives a pathogenic T cell population that induces autoimmune inflammation
-
C.L. Langrish, Y. Chen, W.M. Blumenschein, J. Mattson, B. Basham, J.D. Sedgwick, T. McClanahan, R.A. Kastelein, and D.J. Cua IL-23 drives a pathogenic T cell population that induces autoimmune inflammation J. Exp. Med. 201 2005 233 240
-
(2005)
J. Exp. Med.
, vol.201
, pp. 233-240
-
-
Langrish, C.L.1
Chen, Y.2
Blumenschein, W.M.3
Mattson, J.4
Basham, B.5
Sedgwick, J.D.6
McClanahan, T.7
Kastelein, R.A.8
Cua, D.J.9
-
33
-
-
24644441010
-
TGF-beta signaling in T cells: Roles in lymphoid and epithelial neoplasia
-
J.J. Letterio TGF-beta signaling in T cells: roles in lymphoid and epithelial neoplasia Oncogene 24 2005 5701 5712
-
(2005)
Oncogene
, vol.24
, pp. 5701-5712
-
-
Letterio, J.J.1
-
34
-
-
0031944290
-
Regulation of immune responses by TGF-beta
-
J.J. Letterio, and A.B. Roberts Regulation of immune responses by TGF-beta Annu. Rev. Immunol. 16 1998 137 161
-
(1998)
Annu. Rev. Immunol.
, vol.16
, pp. 137-161
-
-
Letterio, J.J.1
Roberts, A.B.2
-
35
-
-
18644381773
-
TGF-beta 1 uses distinct mechanisms to inhibit IFN-gamma expression in CD4+ T cells at priming and at recall: Differential involvement of Stat4 and T-bet
-
J.T. Lin, S.L. Martin, L. Xia, and J.D. Gorham TGF-beta 1 uses distinct mechanisms to inhibit IFN-gamma expression in CD4+ T cells at priming and at recall: differential involvement of Stat4 and T-bet J. Immunol. 174 2005 5950 5958
-
(2005)
J. Immunol.
, vol.174
, pp. 5950-5958
-
-
Lin, J.T.1
Martin, S.L.2
Xia, L.3
Gorham, J.D.4
-
36
-
-
8444226727
-
Silencing T-bet defines a critical role in the differentiation of autoreactive T lymphocytes
-
A.E. Lovett-Racke, A.E. Rocchini, J. Choy, S.C. Northrop, R.Z. Hussain, R.B. Ratts, D. Sikder, and M.K. Racke Silencing T-bet defines a critical role in the differentiation of autoreactive T lymphocytes Immunity 21 2004 719 731
-
(2004)
Immunity
, vol.21
, pp. 719-731
-
-
Lovett-Racke, A.E.1
Rocchini, A.E.2
Choy, J.3
Northrop, S.C.4
Hussain, R.Z.5
Ratts, R.B.6
Sikder, D.7
Racke, M.K.8
-
38
-
-
0035554676
-
Regulatory T cells in the control of immune pathology
-
K.J. Maloy, and F. Powrie Regulatory T cells in the control of immune pathology Nat. Immunol. 2 2001 816 822
-
(2001)
Nat. Immunol.
, vol.2
, pp. 816-822
-
-
Maloy, K.J.1
Powrie, F.2
-
39
-
-
0034691541
-
TGF-beta 1 differentially regulates IL-2 expression and [3H]-thymidine incorporation in CD3 epsilon mAb- and CD28 mAb-activated splenocytes and thymocytes
-
S.C. McKarns, and N.E. Kaminski TGF-beta 1 differentially regulates IL-2 expression and [3H]-thymidine incorporation in CD3 epsilon mAb- and CD28 mAb-activated splenocytes and thymocytes Immunopharmacology 48 2000 101 115
-
(2000)
Immunopharmacology
, vol.48
, pp. 101-115
-
-
McKarns, S.C.1
Kaminski, N.E.2
-
41
-
-
0036301997
-
Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction
-
A.C. Mullen, A.S. Hutchins, F.A. High, H.W. Lee, K.J. Sykes, L.A. Chodosh, and S.L. Reiner Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction Nat. Immunol. 3 2002 652 658
-
(2002)
Nat. Immunol.
, vol.3
, pp. 652-658
-
-
Mullen, A.C.1
Hutchins, A.S.2
High, F.A.3
Lee, H.W.4
Sykes, K.J.5
Chodosh, L.A.6
Reiner, S.L.7
-
42
-
-
0346962972
-
Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation
-
C.A. Murphy, C.L. Langrish, Y. Chen, W. Blumenschein, T. McClanahan, R.A. Kastelein, J.D. Sedgwick, and D.J. Cua Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation J. Exp. Med. 198 2003 1951 1957
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1951-1957
-
-
Murphy, C.A.1
Langrish, C.L.2
Chen, Y.3
Blumenschein, W.4
McClanahan, T.5
Kastelein, R.A.6
Sedgwick, J.D.7
Cua, D.J.8
-
43
-
-
0036754255
-
Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses
-
S. Nakae, Y. Komiyama, A. Nambu, K. Sudo, M. Iwase, I. Homma, K. Sekikawa, M. Asano, and Y. Iwakura Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses Immunity 17 2002 375 387
-
(2002)
Immunity
, vol.17
, pp. 375-387
-
-
Nakae, S.1
Komiyama, Y.2
Nambu, A.3
Sudo, K.4
Iwase, M.5
Homma, I.6
Sekikawa, K.7
Asano, M.8
Iwakura, Y.9
-
44
-
-
0035801335
-
Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta
-
K. Nakamura, A. Kitani, and W. Strober Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta J. Exp. Med. 194 2001 629 644
-
(2001)
J. Exp. Med.
, vol.194
, pp. 629-644
-
-
Nakamura, K.1
Kitani, A.2
Strober, W.3
-
45
-
-
0030611757
-
Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling
-
A. Nakao, M. Afrakhte, A. Moren, T. Nakayama, J.L. Christian, R. Heuchel, S. Itoh, M. Kawabata, N.E. Heldin, C.H. Heldin, and P. ten Dijke Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling Nature 389 1997 631 635
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
Afrakhte, M.2
Moren, A.3
Nakayama, T.4
Christian, J.L.5
Heuchel, R.6
Itoh, S.7
Kawabata, M.8
Heldin, N.E.9
Heldin, C.H.10
Ten Dijke, P.11
-
46
-
-
85047692430
-
IL-10-producing and naturally occurring CD4+ Tregs: Limiting collateral damage
-
A. O'Garra, P.L. Vieira, P. Vieira, and A.E. Goldfeld IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage J. Clin. Invest. 114 2004 1372 1378
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1372-1378
-
-
O'Garra, A.1
Vieira, P.L.2
Vieira, P.3
Goldfeld, A.E.4
-
47
-
-
0842324613
-
Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice
-
A. Ogawa, A. Andoh, Y. Araki, T. Bamba, and Y. Fujiyama Neutralization of interleukin-17 aggravates dextran sulfate sodium-induced colitis in mice Clin. Immunol. 110 2004 55 62
-
(2004)
Clin. Immunol.
, vol.110
, pp. 55-62
-
-
Ogawa, A.1
Andoh, A.2
Araki, Y.3
Bamba, T.4
Fujiyama, Y.5
-
48
-
-
13144259627
-
Interleukin 6 plays a key role in the development of antigen-induced arthritis
-
S. Ohshima, Y. Saeki, T. Mima, M. Sasai, K. Nishioka, S. Nomura, M. Kopf, Y. Katada, T. Tanaka, M. Suemura, and T. Kishimoto Interleukin 6 plays a key role in the development of antigen-induced arthritis Proc. Natl. Acad. Sci. USA 95 1998 8222 8226
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 8222-8226
-
-
Ohshima, S.1
Saeki, Y.2
Mima, T.3
Sasai, M.4
Nishioka, K.5
Nomura, S.6
Kopf, M.7
Katada, Y.8
Tanaka, T.9
Suemura, M.10
Kishimoto, T.11
-
49
-
-
0031920882
-
IL-6-deficient mice are resistant to the induction of experimental autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein
-
Y. Okuda, S. Sakoda, C.C. Bernard, H. Fujimura, Y. Saeki, T. Kishimoto, and T. Yanagihara IL-6-deficient mice are resistant to the induction of experimental autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein Int. Immunol. 10 1998 703 708
-
(1998)
Int. Immunol.
, vol.10
, pp. 703-708
-
-
Okuda, Y.1
Sakoda, S.2
Bernard, C.C.3
Fujimura, H.4
Saeki, Y.5
Kishimoto, T.6
Yanagihara, T.7
-
50
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12
-
B. Oppmann, R. Lesley, B. Blom, J.C. Timans, Y. Xu, B. Hunte, F. Vega, N. Yu, J. Wang, and K. Singh Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12 Immunity 13 2000 715 725
-
(2000)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
Lesley, R.2
Blom, B.3
Timans, J.C.4
Xu, Y.5
Hunte, B.6
Vega, F.7
Yu, N.8
Wang, J.9
Singh, K.10
-
51
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
H. Park, Z. Li, X.O. Yang, S.H. Chang, R. Nurieva, Y.H. Wang, Y. Wang, L. Hood, Z. Zhu, Q. Tian, and C. Dong A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17 Nat. Immunol. 6 2005 1133 1141
-
(2005)
Nat. Immunol.
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
Chang, S.H.4
Nurieva, R.5
Wang, Y.H.6
Wang, Y.7
Hood, L.8
Zhu, Z.9
Tian, Q.10
Dong, C.11
-
52
-
-
0037436119
-
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells
-
C. Pasare, and R. Medzhitov Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cells Science 299 2003 1033 1036
-
(2003)
Science
, vol.299
, pp. 1033-1036
-
-
Pasare, C.1
Medzhitov, R.2
-
53
-
-
0037099613
-
CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness
-
C.A. Piccirillo, J.J. Letterio, A.M. Thornton, R.S. McHugh, M. Mamura, H. Mizuhara, and E.M. Shevach CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness J. Exp. Med. 196 2002 237 246
-
(2002)
J. Exp. Med.
, vol.196
, pp. 237-246
-
-
Piccirillo, C.A.1
Letterio, J.J.2
Thornton, A.M.3
McHugh, R.S.4
Mamura, M.5
Mizuhara, H.6
Shevach, E.M.7
-
54
-
-
0029085294
-
T cells in inflammatory bowel disease: Protective and pathogenic roles
-
F. Powrie T cells in inflammatory bowel disease: protective and pathogenic roles Immunity 3 1995 171 174
-
(1995)
Immunity
, vol.3
, pp. 171-174
-
-
Powrie, F.1
-
55
-
-
0742272509
-
Toll-like receptors and dendritic cells: For whom the bug tolls
-
C. Reis e Sousa Toll-like receptors and dendritic cells: for whom the bug tolls Semin. Immunol. 16 2004 27 34
-
(2004)
Semin. Immunol.
, vol.16
, pp. 27-34
-
-
Reis, E.1
Sousa, C.2
-
56
-
-
17044377812
-
IL-6 increases primed cell expansion and survival
-
I. Rochman, W.E. Paul, and S.Z. Ben-Sasson IL-6 increases primed cell expansion and survival J. Immunol. 174 2005 4761 4767
-
(2005)
J. Immunol.
, vol.174
, pp. 4761-4767
-
-
Rochman, I.1
Paul, W.E.2
Ben-Sasson, S.Z.3
-
57
-
-
16844365788
-
Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self
-
S. Sakaguchi Naturally arising Foxp3-expressing CD25+CD4+ regulatory T cells in immunological tolerance to self and non-self Nat. Immunol. 6 2005 345 352
-
(2005)
Nat. Immunol.
, vol.6
, pp. 345-352
-
-
Sakaguchi, S.1
-
58
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
Y. Shi, and J. Massague Mechanisms of TGF-beta signaling from cell membrane to the nucleus Cell 113 2003 685 700
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
59
-
-
0026799402
-
Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease
-
M.M. Shull, I. Ormsby, A.B. Kier, S. Pawlowski, R.J. Diebold, M. Yin, R. Allen, C. Sidman, G. Proetzel, and D. Calvin Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease Nature 359 1992 693 699
-
(1992)
Nature
, vol.359
, pp. 693-699
-
-
Shull, M.M.1
Ormsby, I.2
Kier, A.B.3
Pawlowski, S.4
Diebold, R.J.5
Yin, M.6
Allen, R.7
Sidman, C.8
Proetzel, G.9
Calvin, D.10
-
60
-
-
0141924778
-
Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function
-
D.B. Stetson, M. Mohrs, R.L. Reinhardt, J.L. Baron, Z.E. Wang, L. Gapin, M. Kronenberg, and R.M. Locksley Constitutive cytokine mRNAs mark natural killer (NK) and NK T cells poised for rapid effector function J. Exp. Med. 198 2003 1069 1076
-
(2003)
J. Exp. Med.
, vol.198
, pp. 1069-1076
-
-
Stetson, D.B.1
Mohrs, M.2
Reinhardt, R.L.3
Baron, J.L.4
Wang, Z.E.5
Gapin, L.6
Kronenberg, M.7
Locksley, R.M.8
-
61
-
-
0028144631
-
Functional recognition of in vivo processed self antigen
-
B. Stockinger, and B. Hausmann Functional recognition of in vivo processed self antigen Int. Immunol. 6 1994 247 254
-
(1994)
Int. Immunol.
, vol.6
, pp. 247-254
-
-
Stockinger, B.1
Hausmann, B.2
-
62
-
-
8044250881
-
Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells
-
S.J. Szabo, A.S. Dighe, U. Gubler, and K.M. Murphy Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells J. Exp. Med. 185 1997 817 824
-
(1997)
J. Exp. Med.
, vol.185
, pp. 817-824
-
-
Szabo, S.J.1
Dighe, A.S.2
Gubler, U.3
Murphy, K.M.4
-
63
-
-
0034677646
-
A novel transcription factor, T-bet, directs Th1 lineage commitment
-
S.J. Szabo, S.T. Kim, G.L. Costa, X. Zhang, C.G. Fathman, and L.H. Glimcher A novel transcription factor, T-bet, directs Th1 lineage commitment Cell 100 2000 655 669
-
(2000)
Cell
, vol.100
, pp. 655-669
-
-
Szabo, S.J.1
Kim, S.T.2
Costa, G.L.3
Zhang, X.4
Fathman, C.G.5
Glimcher, L.H.6
-
64
-
-
0030890718
-
Gp130 and the interleukin-6 family of cytokines
-
T. Taga, and T. Kishimoto Gp130 and the interleukin-6 family of cytokines Annu. Rev. Immunol. 15 1997 797 819
-
(1997)
Annu. Rev. Immunol.
, vol.15
, pp. 797-819
-
-
Taga, T.1
Kishimoto, T.2
-
65
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
A.M. Thornton, and E.M. Shevach CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production J. Exp. Med. 188 1998 287 296
-
(1998)
J. Exp. Med.
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevach, E.M.2
-
66
-
-
0033602101
-
Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway
-
L. Ulloa, J. Doody, and J. Massague Inhibition of transforming growth factor-beta/SMAD signalling by the interferon-gamma/STAT pathway Nature 397 1999 710 713
-
(1999)
Nature
, vol.397
, pp. 710-713
-
-
Ulloa, L.1
Doody, J.2
Massague, J.3
-
67
-
-
14744284737
-
IL-23 up-regulates IL-10 and induces IL-17 synthesis by polyclonally activated naive T cells in human
-
S. Vanden Eijnden, S. Goriely, D. De Wit, F. Willems, and M. Goldman IL-23 up-regulates IL-10 and induces IL-17 synthesis by polyclonally activated naive T cells in human Eur. J. Immunol. 35 2005 469 475
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 469-475
-
-
Vanden Eijnden, S.1
Goriely, S.2
De Wit, D.3
Willems, F.4
Goldman, M.5
-
68
-
-
0028152937
-
Transforming growth factor beta: The good, the bad, and the ugly
-
S.M. Wahl Transforming growth factor beta: the good, the bad, and the ugly J. Exp. Med. 180 1994 1587 1590
-
(1994)
J. Exp. Med.
, vol.180
, pp. 1587-1590
-
-
Wahl, S.M.1
-
69
-
-
0027392551
-
Reversal of acute and chronic synovial inflammation by anti-transforming growth factor beta
-
S.M. Wahl, J.B. Allen, G.L. Costa, H.L. Wong, and J.R. Dasch Reversal of acute and chronic synovial inflammation by anti-transforming growth factor beta J. Exp. Med. 177 1993 225 230
-
(1993)
J. Exp. Med.
, vol.177
, pp. 225-230
-
-
Wahl, S.M.1
Allen, J.B.2
Costa, G.L.3
Wong, H.L.4
Dasch, J.R.5
-
70
-
-
0030810155
-
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
-
W. Zheng, and R.A. Flavell The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells Cell 89 1997 587 596
-
(1997)
Cell
, vol.89
, pp. 587-596
-
-
Zheng, W.1
Flavell, R.A.2
|