CD23 defines two distinct subsets of immature B cells which differ in their responses to T cell help signals

International Immunology

Volumn 14, Issue 2, 2002, Pages 157-166

  Chung, James B ^a   Sater, Richard A ^a   Fields, Michele L ^b   Erikson, Jan ^b   Monroe, John G ^a,c  

^a Division of Rheumatology   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c WISTAR INSTITUTE   (United States)

Author keywords

B cell subsets; B lymphocytes; CD23; Cell trafficking; T cell B cell collaboration

Indexed keywords

B LYMPHOCYTE RECEPTOR; CD23 ANTIGEN;

ANIMAL CELL; APOPTOSIS; ARTICLE; B LYMPHOCYTE; CELL INTERACTION; CELL SELECTION; CELL SURFACE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; FEMALE; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; SPLEEN; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

EID: 0036163380     PISSN: 09538178     EISSN: None     Source Type: Journal    
DOI: 10.1093/intimm/14.2.157     Document Type: Article

References (51)

1. Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow
2. Generation and regeneration of cells of the B-lymphocyte lineage
3. Cellular stages and molecular steps of murine B-cell development
4. B cell development in the bone marrow
5. Peripheral B cell maturation. II. Heat-stable antigen(hi) splenic B cells are an immature developmental intermediate in the production of long-lived marrow-derived B cells
6. Characterization of immature B cells by a novel monoclonal antibody, by turnover and by mitogen reactivity
7. hi and exhibit unique signaling characteristics
8. Transitional B cells are the target of negative selection in the B cell compartment
9. Acquisition of surface IgD fails to protect from tolerance-induction. Both surface IgM- and surface IgD-mediated signals induce apoptosis of immature murine B lymphocytes
10. Developmental regulation of B lymphocyte immune tolerance compartmentalizes clonal selection from receptor selection
11. B cell receptor-induced apoptosis in primary transitional murine B cells: Signaling requirements and modulation by T cell help
12. B cell development in the spleen takes place in discrete steps and is determined by the quality of B cell receptor-derived signals
13. 1 transition of resting B lymphocytes
14. MRL-lpr/lpr mice exhibit a defect in maintaining developmental arrest and follicular exclusion of anti-double-stranded DNA B cells
15. In situ studies of the primary immune response to (4-hydroxy-3-nitrophenyl)acetyl. I. The architecture and dynamics of responding cell populations
16. In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. I. In vivo expression of CD40 ligand, cytokines, and antibody production delineates sites of cognate T-B cell interactions
17. Sites of B-cell activation in vivo
18. Sites of B lymphocyte selection, activation, and tolerance in spleen
19. Sites of specific B cell activation in primary and secondary responses to T cell-dependent and T cell-independent antigens
20. Germinal centres in T-cell-dependent antibody responses
21. B-cell receptor regulation of peripheral B cells
22. Signaling thresholds and interclonal competition in preimmune B-cell selection
23. A theory of self-nonself discrimination
24. Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7
25. Expression and functional significance of an additional ligand for CTLA-4
26. B70 antigen is a second ligand for CTLA-4 and CD28
27. Comparative analysis of B7-1 and B7-2 costimulatory ligands: Expression and function
28. + T cells
29. L
30. Distinct signal thresholds for the unique antigen receptor-linked gene expression programs in mature and immature B cells
31. Differential up-regulation of the B7-1 and B7-2 costimulatory molecules after Ig receptor engagement by antigen
32. Substrate and inhibitor specificity of interleukin-1 beta-converting enzyme and related caspases
33. Structure of recombinant human CPP32 in complex with the tetrapeptide acetyl-Asp-Val-Ala-Asp fluoromethyl ketone
34. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
35. The humoral immune response in the spleen
36. B-cell activation versus tolerance-the central role of immunoglobulin receptor engagement and T-cell help
37. Visualization of specific B and T lymphocyte interactions in the lymph node
38. Initiation of autoimmunity to the p53 tumor suppressor protein by complexes of p53 and SV40 large T antigen
39. Virus or a hapten-carrier complex can activate autoreactive B cells by providing linked T help
40. Induction of self-tolerance in T cells but not B cells of transgenic mice expressing little self antigen
41. + T cells in vitro: Characteristics and antigen-presenting cell requirements
42. Naive versus memory CD4 T cell response to antigen. Memory cells are less dependent on accessory cell costimulation and can respond to many antigen-presenting cell types including resting B cells
43. Control of the immune response at the level of antigen-presenting cells: A comparison of the function of dendritic cells and B lymphocytes
44. A quantitative analysis of antigen-presenting cell function: Activated B cells stimulate naive CD4 T cells but are inferior to dendritic cells in providing costimulation
45. Influence of B cell receptor ligation and TCR affinity on T-B collaboration in vitro
46. CD28/B7 system of T cell costimulation
47. CTLA-4 regulates induction of anergy in vivo
48. Human 87-1 (CD80) and B7-2 (CD86) bind with similar avidities but distinct kinetics to CD28 and CTLA-4 receptors
49. Murine B1 B cells require IL-5 for optimal T cell-dependent activation
50. A role for MHC class II antigen processing in B cell development
51. Syk tyrosine kinase is required for the positive selection of immature B cells into the recirculating B cell pool