메뉴 건너뛰기




Volumn 133, Issue 2, 2009, Pages 218-227

A role for autoantibodies in enhancement of pro-inflammatory cytokine responses to a self-antigen, thyroid peroxidase

Author keywords

Autoantibodies; Autoimmune thyroid disease; Cytokines; Hashimoto's thyroiditis; Inflammation

Indexed keywords

AUTOANTIBODY; CYTOKINE; FC RECEPTOR; GAMMA INTERFERON; IMMUNOGLOBULIN G; INTERLEUKIN 10; INTERLEUKIN 6; THYROID PEROXIDASE; THYROID PEROXIDASE ANTIBODY; TUMOR NECROSIS FACTOR ALPHA;

EID: 70349968091     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2009.07.014     Document Type: Article
Times cited : (40)

References (46)
  • 1
    • 34249313377 scopus 로고    scopus 로고
    • Autoantibodies as predictors of disease: the clinical and experimental evidence
    • Bizzaro N. Autoantibodies as predictors of disease: the clinical and experimental evidence. Autoimmun. Rev. 6 6 (2007 Jun) 325-333
    • (2007) Autoimmun. Rev. , vol.6 , Issue.6 , pp. 325-333
    • Bizzaro, N.1
  • 2
    • 33750053265 scopus 로고    scopus 로고
    • Thyroid peroxidase and thyroglobulin auto-antibodies in patients with newly diagnosed overt hypothyroidism
    • Carle A., Laurberg P., Knudsen N., Perrild H., Ovesen L., Rasmussen L.B., et al. Thyroid peroxidase and thyroglobulin auto-antibodies in patients with newly diagnosed overt hypothyroidism. Autoimmunity 39 6 (2006 Sep) 497-503
    • (2006) Autoimmunity , vol.39 , Issue.6 , pp. 497-503
    • Carle, A.1    Laurberg, P.2    Knudsen, N.3    Perrild, H.4    Ovesen, L.5    Rasmussen, L.B.6
  • 3
  • 4
    • 0031024366 scopus 로고    scopus 로고
    • Anti-thyroglobulin autoantibodies in autoimmune thyroid diseases: cross-reactive or pathogenic?
    • Tomer Y. Anti-thyroglobulin autoantibodies in autoimmune thyroid diseases: cross-reactive or pathogenic?. Clin. Immunol. Immunopathol. 82 1 (1997 Jan) 3-11
    • (1997) Clin. Immunol. Immunopathol. , vol.82 , Issue.1 , pp. 3-11
    • Tomer, Y.1
  • 5
    • 0034812467 scopus 로고    scopus 로고
    • Natural autoantibodies and complement promote the uptake of a self antigen, human thyroglobulin, by B cells and the proliferation of thyroglobulin-reactive CD4(+) T cells in healthy individuals
    • Nielsen C.H., Leslie R.G., Jepsen B.S., Kazatchkine M.D., Kaveri S.V., and Fischer E. Natural autoantibodies and complement promote the uptake of a self antigen, human thyroglobulin, by B cells and the proliferation of thyroglobulin-reactive CD4(+) T cells in healthy individuals. Eur. J. Immunol. 31 9 (2001 Sep) 2660-2668
    • (2001) Eur. J. Immunol. , vol.31 , Issue.9 , pp. 2660-2668
    • Nielsen, C.H.1    Leslie, R.G.2    Jepsen, B.S.3    Kazatchkine, M.D.4    Kaveri, S.V.5    Fischer, E.6
  • 6
    • 33746618003 scopus 로고    scopus 로고
    • Establishment of reference distributions and decision values for thyroid antibodies against thyroid peroxidase (TPOAb), thyroglobulin (TgAb) and the thyrotropin receptor (TRAb)
    • Jensen E.A., Petersen P.H., Blaabjerg O., Hansen P.S., Brix T.H., and Hegedus L. Establishment of reference distributions and decision values for thyroid antibodies against thyroid peroxidase (TPOAb), thyroglobulin (TgAb) and the thyrotropin receptor (TRAb). Clin. Chem. Lab. Med. 44 8 (2006) 991-998
    • (2006) Clin. Chem. Lab. Med. , vol.44 , Issue.8 , pp. 991-998
    • Jensen, E.A.1    Petersen, P.H.2    Blaabjerg, O.3    Hansen, P.S.4    Brix, T.H.5    Hegedus, L.6
  • 7
    • 0029046372 scopus 로고
    • The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham Survey
    • Vanderpump M.P., Tunbridge W.M., French J.M., Appleton D., Bates D., Clark F., et al. The incidence of thyroid disorders in the community: a twenty-year follow-up of the Whickham Survey. Clin. Endocrinol. (Oxf) 43 1 (1995 Jul) 55-68
    • (1995) Clin. Endocrinol. (Oxf) , vol.43 , Issue.1 , pp. 55-68
    • Vanderpump, M.P.1    Tunbridge, W.M.2    French, J.M.3    Appleton, D.4    Bates, D.5    Clark, F.6
  • 8
    • 0000152214 scopus 로고
    • Precipitating and complement-fixing antibodies in Hashimoto's disease
    • Trotter W.R., Belyavin G., and Waddams A. Precipitating and complement-fixing antibodies in Hashimoto's disease. Proc. R. Soc. Med. 50 11 (1957 Nov) 961-962
    • (1957) Proc. R. Soc. Med. , vol.50 , Issue.11 , pp. 961-962
    • Trotter, W.R.1    Belyavin, G.2    Waddams, A.3
  • 9
    • 0019401030 scopus 로고
    • Presence of the organ-specific 'microsomal' autoantigen on the surface of human thyroid cells in culture: its involvement in complement-mediated cytotoxicity
    • Khoury E.L., Hammond L., Bottazzo G.F., and Doniach D. Presence of the organ-specific 'microsomal' autoantigen on the surface of human thyroid cells in culture: its involvement in complement-mediated cytotoxicity. Clin. Exp. Immunol. 45 2 (1981 Aug) 316-328
    • (1981) Clin. Exp. Immunol. , vol.45 , Issue.2 , pp. 316-328
    • Khoury, E.L.1    Hammond, L.2    Bottazzo, G.F.3    Doniach, D.4
  • 10
    • 0024410181 scopus 로고
    • Terminal complement complexes and C1/C1 inhibitor complexes in autoimmune thyroid disease
    • Weetman A.P., Cohen S.B., Oleesky D.A., and Morgan B.P. Terminal complement complexes and C1/C1 inhibitor complexes in autoimmune thyroid disease. Clin. Exp. Immunol. 77 1 (1989 Jul) 25-30
    • (1989) Clin. Exp. Immunol. , vol.77 , Issue.1 , pp. 25-30
    • Weetman, A.P.1    Cohen, S.B.2    Oleesky, D.A.3    Morgan, B.P.4
  • 12
    • 0027135155 scopus 로고
    • Antibodies producing complement-mediated thyroid cytotoxicity in patients with atrophic or goitrous autoimmune thyroiditis
    • Chiovato L., Bassi P., Santini F., Mammoli C., Lapi P., Carayon P., et al. Antibodies producing complement-mediated thyroid cytotoxicity in patients with atrophic or goitrous autoimmune thyroiditis. J. Clin. Endocrinol. Metab. 77 6 (1993 Dec) 1700-1705
    • (1993) J. Clin. Endocrinol. Metab. , vol.77 , Issue.6 , pp. 1700-1705
    • Chiovato, L.1    Bassi, P.2    Santini, F.3    Mammoli, C.4    Lapi, P.5    Carayon, P.6
  • 14
    • 0021211312 scopus 로고
    • Antibody-dependent cell mediated cytotoxicity against human thyroid cells in Hashimoto's thyroiditis but not Graves' disease
    • Bogner U., Schleusener H., and Wall J.R. Antibody-dependent cell mediated cytotoxicity against human thyroid cells in Hashimoto's thyroiditis but not Graves' disease. J. Clin. Endocrinol. Metab. 59 4 (1984 Oct) 734-738
    • (1984) J. Clin. Endocrinol. Metab. , vol.59 , Issue.4 , pp. 734-738
    • Bogner, U.1    Schleusener, H.2    Wall, J.R.3
  • 15
    • 0031029105 scopus 로고    scopus 로고
    • Recombinant thyroid peroxidase-specific Fab converted to immunoglobulin G (IgG) molecules: evidence for thyroid cell damage by IgG1, but not IgG4, autoantibodies
    • Guo J., Jaume J.C., Rapoport B., and McLachlan S.M. Recombinant thyroid peroxidase-specific Fab converted to immunoglobulin G (IgG) molecules: evidence for thyroid cell damage by IgG1, but not IgG4, autoantibodies. J. Clin. Endocrinol. Metab. 82 3 (1997 Mar) 925-931
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , Issue.3 , pp. 925-931
    • Guo, J.1    Jaume, J.C.2    Rapoport, B.3    McLachlan, S.M.4
  • 16
    • 0029943281 scopus 로고    scopus 로고
    • Antibody-dependent cell-mediated cytotoxicity in autoimmune thyroid disease: relationship to antithyroperoxidase antibodies
    • Rodien P., Madec A.M., Ruf J., Rajas F., Bornet H., Carayon P., et al. Antibody-dependent cell-mediated cytotoxicity in autoimmune thyroid disease: relationship to antithyroperoxidase antibodies. J. Clin. Endocrinol. Metab. 81 7 (1996 Jul) 2595-2600
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , Issue.7 , pp. 2595-2600
    • Rodien, P.1    Madec, A.M.2    Ruf, J.3    Rajas, F.4    Bornet, H.5    Carayon, P.6
  • 18
    • 0033980502 scopus 로고    scopus 로고
    • Evidence for antigen presentation to sensitized T cells by thyroid peroxidase (TPO)-specific B cells in mice injected with fibroblasts co-expressing TPO and MHC class II
    • Guo J., Wang Y., Rapoport B., and McLachlan S.M. Evidence for antigen presentation to sensitized T cells by thyroid peroxidase (TPO)-specific B cells in mice injected with fibroblasts co-expressing TPO and MHC class II. Clin. Exp. Immunol. 119 1 (2000 Jan) 38-46
    • (2000) Clin. Exp. Immunol. , vol.119 , Issue.1 , pp. 38-46
    • Guo, J.1    Wang, Y.2    Rapoport, B.3    McLachlan, S.M.4
  • 19
    • 0030975414 scopus 로고    scopus 로고
    • Analysis of antibody-dependent cell-mediated cytotoxicity in autoimmune thyroid disease
    • Metcalfe R.A., Oh Y.S., Stroud C., Arnold K., and Weetman A.P. Analysis of antibody-dependent cell-mediated cytotoxicity in autoimmune thyroid disease. Autoimmunity 25 2 (1997) 65-72
    • (1997) Autoimmunity , vol.25 , Issue.2 , pp. 65-72
    • Metcalfe, R.A.1    Oh, Y.S.2    Stroud, C.3    Arnold, K.4    Weetman, A.P.5
  • 20
    • 0035555276 scopus 로고    scopus 로고
    • Determinants of autoimmune thyroid disease
    • Weetman A.P. Determinants of autoimmune thyroid disease. Nat. Immunol. 2 9 (2001 Sep) 769-770
    • (2001) Nat. Immunol. , vol.2 , Issue.9 , pp. 769-770
    • Weetman, A.P.1
  • 21
    • 1642513794 scopus 로고    scopus 로고
    • Autoantibodies in autoimmune thyroid disease promote immune complex formation with self antigens and increase B cell and CD4+ T cell proliferation in response to self antigens
    • Nielsen C.H., Hegedus L., and Leslie R.G. Autoantibodies in autoimmune thyroid disease promote immune complex formation with self antigens and increase B cell and CD4+ T cell proliferation in response to self antigens. Eur. J. Immunol. 34 1 (2004 Jan) 263-272
    • (2004) Eur. J. Immunol. , vol.34 , Issue.1 , pp. 263-272
    • Nielsen, C.H.1    Hegedus, L.2    Leslie, R.G.3
  • 22
    • 0015882295 scopus 로고
    • Antigen-macrophage interaction. II. Relative roles of cytophilic antibody and other membrane sites
    • Cohen B.E., Rosenthal A.S., and Paul W.E. Antigen-macrophage interaction. II. Relative roles of cytophilic antibody and other membrane sites. J. Immunol. 111 3 (1973 Sep) 820-828
    • (1973) J. Immunol. , vol.111 , Issue.3 , pp. 820-828
    • Cohen, B.E.1    Rosenthal, A.S.2    Paul, W.E.3
  • 23
    • 0021343233 scopus 로고
    • Antibodies to hepatitis B surface antigen potentiate the response of human T lymphocyte clones to the same antigen
    • Celis E., and Chang T.W. Antibodies to hepatitis B surface antigen potentiate the response of human T lymphocyte clones to the same antigen. Science 224 4646 (1984 Apr 20) 297-299
    • (1984) Science , vol.224 , Issue.4646 , pp. 297-299
    • Celis, E.1    Chang, T.W.2
  • 24
    • 0022612289 scopus 로고
    • Presentation by peritoneal macrophages: modulation by antibody-antigen complexes
    • Perkins K.A., and Chain B.M. Presentation by peritoneal macrophages: modulation by antibody-antigen complexes. Immunology 58 1 (1986 May) 15-21
    • (1986) Immunology , vol.58 , Issue.1 , pp. 15-21
    • Perkins, K.A.1    Chain, B.M.2
  • 25
    • 0026017326 scopus 로고
    • Effect of antigen/antibody ratio on macrophage uptake, processing, and presentation to T cells of antigen complexed with polyclonal antibodies
    • Manca F., Fenoglio D., Li P.G., Kunkl A., and Celada F. Effect of antigen/antibody ratio on macrophage uptake, processing, and presentation to T cells of antigen complexed with polyclonal antibodies. J. Exp. Med. 173 1 (1991 Jan 1) 37-48
    • (1991) J. Exp. Med. , vol.173 , Issue.1 , pp. 37-48
    • Manca, F.1    Fenoglio, D.2    Li, P.G.3    Kunkl, A.4    Celada, F.5
  • 26
    • 0021810587 scopus 로고
    • Enhanced activation of a T cell line specific for acetylcholine receptor (AChR) by using anti-AChR monoclonal antibodies plus receptors
    • Schalke B.C., Klinkert W.E., Wekerle H., and Dwyer D.S. Enhanced activation of a T cell line specific for acetylcholine receptor (AChR) by using anti-AChR monoclonal antibodies plus receptors. J. Immunol. 134 6 (1985 Jun) 3643-3648
    • (1985) J. Immunol. , vol.134 , Issue.6 , pp. 3643-3648
    • Schalke, B.C.1    Klinkert, W.E.2    Wekerle, H.3    Dwyer, D.S.4
  • 27
    • 0027502743 scopus 로고
    • Specific immune complexes augment in vitro acetylcholine receptor-specific T-cell proliferation
    • Melms A., Weissert R., Klinkert W.E., Schalke B.C., Tzartos S., and Wekerle H. Specific immune complexes augment in vitro acetylcholine receptor-specific T-cell proliferation. Neurology 43 3 Pt 1 (1993 Mar) 583-588
    • (1993) Neurology , vol.43 , Issue.3 PART 1 , pp. 583-588
    • Melms, A.1    Weissert, R.2    Klinkert, W.E.3    Schalke, B.C.4    Tzartos, S.5    Wekerle, H.6
  • 28
    • 34248213007 scopus 로고    scopus 로고
    • Antibody-enhanced cross-presentation of self antigen breaks T cell tolerance
    • Harbers S.O., Crocker A., Catalano G., D'Agati V., Jung S., Desai D.D., et al. Antibody-enhanced cross-presentation of self antigen breaks T cell tolerance. J. Clin. Invest. 117 5 (2007 May) 1361-1369
    • (2007) J. Clin. Invest. , vol.117 , Issue.5 , pp. 1361-1369
    • Harbers, S.O.1    Crocker, A.2    Catalano, G.3    D'Agati, V.4    Jung, S.5    Desai, D.D.6
  • 29
    • 0030576932 scopus 로고    scopus 로고
    • Autoantibody-mediated capture and presentation of autoantigen to T cells via the Fc epsilon receptor by a recombinant human autoantibody Fab converted to IgE
    • Guo J., Quaratino S., Jaume J.C., Costante G., Londei M., McLachlan S.M., et al. Autoantibody-mediated capture and presentation of autoantigen to T cells via the Fc epsilon receptor by a recombinant human autoantibody Fab converted to IgE. J. Immunol. Methods 195 1-2 (1996 Sep 9) 81-92
    • (1996) J. Immunol. Methods , vol.195 , Issue.1-2 , pp. 81-92
    • Guo, J.1    Quaratino, S.2    Jaume, J.C.3    Costante, G.4    Londei, M.5    McLachlan, S.M.6
  • 30
    • 51649103494 scopus 로고    scopus 로고
    • Epitope recognition patterns of thyroid peroxidase autoantibodies in healthy individuals and patients with Hashimoto's thyroiditis
    • Nielsen C.H., Brix T.H., Gardas A., Banga J.P., and Hegedus L. Epitope recognition patterns of thyroid peroxidase autoantibodies in healthy individuals and patients with Hashimoto's thyroiditis. Clin. Endocrinol. (Oxf) 69 4 (2008 Oct) 664-668
    • (2008) Clin. Endocrinol. (Oxf) , vol.69 , Issue.4 , pp. 664-668
    • Nielsen, C.H.1    Brix, T.H.2    Gardas, A.3    Banga, J.P.4    Hegedus, L.5
  • 31
    • 34548801399 scopus 로고    scopus 로고
    • Biological variation of thyroid autoantibodies and thyroglobulin
    • Jensen E., Petersen P.H., Blaabjerg O., and Hegedus L. Biological variation of thyroid autoantibodies and thyroglobulin. Clin. Chem. Lab. Med. 45 8 (2007) 1058-1064
    • (2007) Clin. Chem. Lab. Med. , vol.45 , Issue.8 , pp. 1058-1064
    • Jensen, E.1    Petersen, P.H.2    Blaabjerg, O.3    Hegedus, L.4
  • 32
    • 1542359462 scopus 로고    scopus 로고
    • Aggregation of thyroid autoantibodies in first-degree relatives of patients with autoimmune thyroid disease is mainly due to genes: a twin study
    • Brix T.H., Hansen P.S., Kyvik K.O., and Hegedus L. Aggregation of thyroid autoantibodies in first-degree relatives of patients with autoimmune thyroid disease is mainly due to genes: a twin study. Clin. Endocrinol. (Oxf) 60 3 (2004 Mar) 329-334
    • (2004) Clin. Endocrinol. (Oxf) , vol.60 , Issue.3 , pp. 329-334
    • Brix, T.H.1    Hansen, P.S.2    Kyvik, K.O.3    Hegedus, L.4
  • 33
    • 33846204725 scopus 로고    scopus 로고
    • Production of interleukin (IL)-5 and IL-10 accompanies T helper cell type 1 (Th1) cytokine responses to a major thyroid self-antigen, thyroglobulin, in health and autoimmune thyroid disease
    • Nielsen C.H., Hegedus L., Rieneck K., Moeller A.C., Leslie R.G., and Bendtzen K. Production of interleukin (IL)-5 and IL-10 accompanies T helper cell type 1 (Th1) cytokine responses to a major thyroid self-antigen, thyroglobulin, in health and autoimmune thyroid disease. Clin. Exp. Immunol. 147 2 (2007 Feb) 287-295
    • (2007) Clin. Exp. Immunol. , vol.147 , Issue.2 , pp. 287-295
    • Nielsen, C.H.1    Hegedus, L.2    Rieneck, K.3    Moeller, A.C.4    Leslie, R.G.5    Bendtzen, K.6
  • 34
    • 0029035307 scopus 로고
    • Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants
    • Simitsek P.D., Campbell D.G., Lanzavecchia A., Fairweather N., and Watts C. Modulation of antigen processing by bound antibodies can boost or suppress class II major histocompatibility complex presentation of different T cell determinants. J. Exp. Med. 181 6 (1995 Jun 1) 1957-1963
    • (1995) J. Exp. Med. , vol.181 , Issue.6 , pp. 1957-1963
    • Simitsek, P.D.1    Campbell, D.G.2    Lanzavecchia, A.3    Fairweather, N.4    Watts, C.5
  • 35
    • 0025240576 scopus 로고
    • Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytes
    • Lanzavecchia A. Receptor-mediated antigen uptake and its effect on antigen presentation to class II-restricted T lymphocytes. Annu. Rev. Immunol. 8 (1990) 773-793
    • (1990) Annu. Rev. Immunol. , vol.8 , pp. 773-793
    • Lanzavecchia, A.1
  • 36
    • 10844266513 scopus 로고    scopus 로고
    • Human autoantibodies modulate the T cell epitope repertoire but fail to unmask a pathogenic cryptic epitope
    • Quaratino S., Ruf J., Osman M., Guo J., McLachlan S., Rapoport B., et al. Human autoantibodies modulate the T cell epitope repertoire but fail to unmask a pathogenic cryptic epitope. J. Immunol. 174 1 (2005 Jan 1) 557-563
    • (2005) J. Immunol. , vol.174 , Issue.1 , pp. 557-563
    • Quaratino, S.1    Ruf, J.2    Osman, M.3    Guo, J.4    McLachlan, S.5    Rapoport, B.6
  • 37
    • 0026094306 scopus 로고
    • Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes
    • de Waal M.R., Abrams J., Bennett B., Figdor C.G., and de Vries J.E. Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J. Exp. Med. 174 5 (1991 Nov 1) 1209-1220
    • (1991) J. Exp. Med. , vol.174 , Issue.5 , pp. 1209-1220
    • de Waal, M.R.1    Abrams, J.2    Bennett, B.3    Figdor, C.G.4    de Vries, J.E.5
  • 38
    • 0024454176 scopus 로고
    • Interleukin 4 induces selective production of interleukin 6 from normal human B lymphocytes
    • Smeland E.B., Blomhoff H.K., Funderud S., Shalaby M.R., and Espevik T. Interleukin 4 induces selective production of interleukin 6 from normal human B lymphocytes. J. Exp. Med. 170 4 (1989 Oct 1) 1463-1468
    • (1989) J. Exp. Med. , vol.170 , Issue.4 , pp. 1463-1468
    • Smeland, E.B.1    Blomhoff, H.K.2    Funderud, S.3    Shalaby, M.R.4    Espevik, T.5
  • 40
    • 0024464668 scopus 로고
    • High potential to tumor necrosis factor (TNF-) production of thyroid infiltrating lymphocytes in Hashimoto's thyroiditis: a peculiar feature of destructive thyroid autoimmunity
    • Del Prete G.F., Tiri A., De Carli M., Mariotti S., Pinchera A., Chretien I., et al. High potential to tumor necrosis factor (TNF-) production of thyroid infiltrating lymphocytes in Hashimoto's thyroiditis: a peculiar feature of destructive thyroid autoimmunity. Autoimmunity 4 (1989) 267-276
    • (1989) Autoimmunity , vol.4 , pp. 267-276
    • Del Prete, G.F.1    Tiri, A.2    De Carli, M.3    Mariotti, S.4    Pinchera, A.5    Chretien, I.6
  • 41
    • 0023637828 scopus 로고
    • Enhanced production of gamma-interferon by thyroid-derived T-cell clones from patients with Hashimoto thyroiditis
    • Del Prete G.F., Tiri A., Mariotti S., Pinchera A., Ricci M., and Romagnani S. Enhanced production of gamma-interferon by thyroid-derived T-cell clones from patients with Hashimoto thyroiditis. Clin. Exp. Immunol. 69 2 (1987 Aug) 323-331
    • (1987) Clin. Exp. Immunol. , vol.69 , Issue.2 , pp. 323-331
    • Del Prete, G.F.1    Tiri, A.2    Mariotti, S.3    Pinchera, A.4    Ricci, M.5    Romagnani, S.6
  • 42
    • 0032987199 scopus 로고    scopus 로고
    • Balance of Th1/Th2 cytokines in thyroid autoantibody synthesis in vitro
    • Guo J., Rapoport B., and McLachlan S.M. Balance of Th1/Th2 cytokines in thyroid autoantibody synthesis in vitro. Autoimmunity 30 1 (1999) 1-9
    • (1999) Autoimmunity , vol.30 , Issue.1 , pp. 1-9
    • Guo, J.1    Rapoport, B.2    McLachlan, S.M.3
  • 43
    • 0029843836 scopus 로고    scopus 로고
    • Intrathyroidal cytokine gene expression in Hashimoto's thyroiditis
    • Ajjan R.A., Watson P.F., McIntosh R.S., and Weetman A.P. Intrathyroidal cytokine gene expression in Hashimoto's thyroiditis. Clin. Exp. Immunol. 105 3 (1996 Sep) 523-528
    • (1996) Clin. Exp. Immunol. , vol.105 , Issue.3 , pp. 523-528
    • Ajjan, R.A.1    Watson, P.F.2    McIntosh, R.S.3    Weetman, A.P.4
  • 44
    • 0033928257 scopus 로고    scopus 로고
    • T-regulatory 1 cells: a novel subset of CD4 T cells with immunoregulatory properties
    • Levings M.K., and Roncarolo M.G. T-regulatory 1 cells: a novel subset of CD4 T cells with immunoregulatory properties. J. Allergy Clin. Immunol. 106 1 Pt 2 (2000 Jul) S109-S112
    • (2000) J. Allergy Clin. Immunol. , vol.106 , Issue.1 PART 2
    • Levings, M.K.1    Roncarolo, M.G.2
  • 45
    • 0033579883 scopus 로고    scopus 로고
    • Regulatory T cells in the control of autoimmunity: the essential role of transforming growth factor beta and interleukin 4 in the prevention of autoimmune thyroiditis in rats by peripheral CD4(+)CD45RC(-) cells and CD4(+)CD8(-) thymocytes
    • Seddon B., and Mason D. Regulatory T cells in the control of autoimmunity: the essential role of transforming growth factor beta and interleukin 4 in the prevention of autoimmune thyroiditis in rats by peripheral CD4(+)CD45RC(-) cells and CD4(+)CD8(-) thymocytes. J. Exp. Med. 189 2 (1999 Jan 18) 279-288
    • (1999) J. Exp. Med. , vol.189 , Issue.2 , pp. 279-288
    • Seddon, B.1    Mason, D.2
  • 46
    • 0035018047 scopus 로고    scopus 로고
    • A novel Fc receptor for IgA and IgM is expressed on both hematopoietic and non-hematopoietic tissues
    • Sakamoto N., Shibuya K., Shimizu Y., Yotsumoto K., Miyabayashi T., Sakano S., et al. A novel Fc receptor for IgA and IgM is expressed on both hematopoietic and non-hematopoietic tissues. Eur. J. Immunol. 31 5 (2001 May) 1310-1316
    • (2001) Eur. J. Immunol. , vol.31 , Issue.5 , pp. 1310-1316
    • Sakamoto, N.1    Shibuya, K.2    Shimizu, Y.3    Yotsumoto, K.4    Miyabayashi, T.5    Sakano, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.