메뉴 건너뛰기




Volumn 2, Issue 3, 2002, Pages 195-204

Autoimmune thyroid disease: New models of cell death in autoimmunity

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CELL DEATH RECEPTOR; CELL RECEPTOR; CRYPTIC EPITOPE; CYTOKINE; EPITOPE; THYROID ANTIBODY; UNCLASSIFIED DRUG; FAS ANTIGEN; FAS LIGAND; FASLG PROTEIN, HUMAN; MEMBRANE PROTEIN;

EID: 0036514975     PISSN: 14741733     EISSN: None     Source Type: Journal    
DOI: 10.1038/nri750     Document Type: Review
Times cited : (237)

References (95)
  • 1
    • 0025358777 scopus 로고
    • Autoimmune diseases: The failure of self tolerance
    • Sinha, A. A. Lopez, M. T. & McDevitt, H. O. Autoimmune diseases: the failure of self tolerance. Science 248, 1380-1388 (1990).
    • (1990) Science , vol.248 , pp. 1380-1388
    • Sinha, A.A.1    Lopez, M.T.2    McDevitt, H.O.3
  • 2
    • 0035345428 scopus 로고    scopus 로고
    • Concordance for type 1 diabetes in identical twins is affected by insulin genotype
    • Metcalfe, K. A. et al. Concordance for type 1 diabetes in identical twins is affected by insulin genotype. Diabetes Care 24, 838-842 (2001).
    • (2001) Diabetes Care , vol.24 , pp. 838-842
    • Metcalfe, K.A.1
  • 3
    • 0034453053 scopus 로고    scopus 로고
    • A population-based study of chronic autoimmune hypothyroidism in Danish twins
    • Brix, T. H., Kyvik, K. O. & Hegedus, L. A population-based study of chronic autoimmune hypothyroidism in Danish twins. J. Clin. Endocrinol. Metab. 85, 536-539 (2000).
    • (2000) J. Clin. Endocrinol. Metab. , vol.85 , pp. 536-539
    • Brix, T.H.1    Kyvik, K.O.2    Hegedus, L.3
  • 4
    • 0027315279 scopus 로고
    • Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells
    • Wesselborg, S., Janssen, O. & Kabelitz, D. Induction of activation-driven death (apoptosis) in activated but not resting peripheral blood T cells. J. Immunol. 150, 4338-4345 (1993).
    • (1993) J. Immunol. , vol.150 , pp. 4338-4345
    • Wesselborg, S.1    Janssen, O.2    Kabelitz, D.3
  • 5
    • 0027183703 scopus 로고
    • Activation interferes with the APO-1 pathway in mature human T cells
    • Klas, C., Debatin, K. M., Jonker, R. P., & Krammer, P. H. Activation interferes with the APO-1 pathway in mature human T cells. Int. Immunol. 5, 625-630 (1993). The first demonstration that activated T cells become susceptible to CD95-induced apoptosis.
    • (1993) Int. Immunol. , vol.5 , pp. 625-630
    • Klas, C.1    Debatin, K.M.2    Jonker, R.P.3    Krammer, P.H.4
  • 6
    • 0029150110 scopus 로고
    • Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
    • Sakaguchi, S., Sakaguchi, N., Asano, M., Itoh, M. & Toda. M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor α-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 155, 1151-1164 (1995). Identification of a key population of regulatory T cells.
    • (1995) J. Immunol. , vol.155 , pp. 1151-1164
    • Sakaguchi, S.1    Sakaguchi, N.2    Asano, M.3    Itoh, M.4    Toda, M.5
  • 7
    • 0031939403 scopus 로고    scopus 로고
    • + T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells
    • + T cells inhibit both the induction and effector function of autoreactive T cells and represent a unique lineage of immunoregulatory cells. J. Immunol. 160, 1212-1218 (1998).
    • (1998) J. Immunol. , vol.160 , pp. 1212-1218
    • Suri-Payer, E.1    Amar, A.Z.2    Thornton, A.M.3    Shevach, E.M.4
  • 8
    • 0028926223 scopus 로고
    • Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein
    • Wucherpfennig, K. W. & Strominger, J. L. Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. Cell 80, 695-705 (1995).
    • (1995) Cell , vol.80 , pp. 695-705
    • Wucherpfennig, K.W.1    Strominger, J.L.2
  • 10
    • 0026664422 scopus 로고
    • Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen
    • Lehmann, R. P. V., Forsthuber, T., Miller, A. & Sercarz, E. E. Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen. Nature 358, 155-157 (1992).
    • (1992) Nature , vol.358 , pp. 155-157
    • Lehmann, R.P.V.1    Forsthuber, T.2    Miller, A.3    Sercarz, E.E.4
  • 11
    • 0034642499 scopus 로고    scopus 로고
    • Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b
    • Bachmaier, K. et al. Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b. Nature 403, 211-216 (2000).
    • (2000) Nature , vol.403 , pp. 211-216
    • Bachmaier, K.1
  • 12
    • 0025805789 scopus 로고
    • Tolerance and immune regulation
    • Robey, E. & Urbain. J. Tolerance and immune regulation Immunol. Today 12, 175-177 (1991).
    • (1991) Immunol. Today , vol.12 , pp. 175-177
    • Robey, E.1    Urbain, J.2
  • 14
    • 0035554898 scopus 로고    scopus 로고
    • Multiple sclerosis: A two-stage disease
    • Steinman, L. Multiple sclerosis: a two-stage disease. Nature Immunol. 2, 762-764 (2001).
    • (2001) Nature Immunol. , vol.2 , pp. 762-764
    • Steinman, L.1
  • 15
    • 0028579773 scopus 로고
    • Autoimmune thyroid disease: Further developments in our understanding
    • Weetman, A. P. & McGregor, A. M. Autoimmune thyroid disease: further developments in our understanding Endocr. Rev. 15, 788-830 (1994). A comprehensive review on thyroid autoimmunity.
    • (1994) Endocr. Rev. , vol.15 , pp. 788-830
    • Weetman, A.P.1    McGregor, A.M.2
  • 16
    • 0031034933 scopus 로고    scopus 로고
    • Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis
    • Giordano, C. et al. Potential involvement of Fas and its ligand in the pathogenesis of Hashimoto's thyroiditis. Science 275, 960-963 (1997).
    • (1997) Science , vol.275 , pp. 960-963
    • Giordano, C.1
  • 17
    • 0031901457 scopus 로고    scopus 로고
    • Fas-FasL interactions: A common pathogenetic mechanism in organ-specific autoimmunity
    • De Maria, R. & Testi, R. Fas-FasL interactions: a common pathogenetic mechanism in organ-specific autoimmunity. Immunol. Today 19, 121-125 (1998).
    • (1998) Immunol. Today , vol.19 , pp. 121-125
    • De Maria, R.1    Testi, R.2
  • 18
    • 0032907268 scopus 로고    scopus 로고
    • Fas/Fas ligand-driven T cell apoptosis as a consequence of ineffective thyroid immunoprivilege in Hashimoto's thyroiditis
    • Stassi, G. et al. Fas/Fas ligand-driven T cell apoptosis as a consequence of ineffective thyroid immunoprivilege in Hashimoto's thyroiditis. J. Immunol. 162, 263-267 (1999). Unexpected findings indicating that thyrocytes kill infiltrating T cells in Hashimoto's thyroiditis.
    • (1999) J. Immunol. , vol.162 , pp. 263-267
    • Stassi, G.1
  • 19
    • 5944261448 scopus 로고    scopus 로고
    • Control of target cells survival in thyroid autoimmunity by T helper cytokines via regulation of apoptotic proteins
    • Stassi, G. et al. Control of target cells survival in thyroid autoimmunity by T helper cytokines via regulation of apoptotic proteins Nature Immunol. 1, 1-6 (2000). A demonstration that production of T-helper cytokines promotes survival or death of thyrocytes during the autoimmune response.
    • (2000) Nature Immunol. , vol.1 , pp. 1-6
    • Stassi, G.1
  • 22
    • 0026078983 scopus 로고
    • Spatial correlation between thyroid epithelial cells expressing class II MHC molecules and interferon-γ-containing lymphocytes in human thyroid autoimmune disease
    • Hamilton, F., Black, M., Farquharson, M. A., Stewart, C. & Foulis, A. K. Spatial correlation between thyroid epithelial cells expressing class II MHC molecules and interferon-γ-containing lymphocytes in human thyroid autoimmune disease. Clin. Exp. Immunol. 83, 64-68 (1991).
    • (1991) Clin. Exp. Immunol. , vol.83 , pp. 64-68
    • Hamilton, F.1    Black, M.2    Farquharson, M.A.3    Stewart, C.4    Foulis, A.K.5
  • 23
    • 0029746157 scopus 로고    scopus 로고
    • Induction of Graves-like disease in mice by immunization with fibroblasts transfected with the thyrotropin receptor and a class II molecule
    • Shimojo, N. et al. Induction of Graves-like disease in mice by immunization with fibroblasts transfected with the thyrotropin receptor and a class II molecule. Proc. Natl Acad. Sci. USA 93, 11074-11079 (1996). The first experimental model of Graves' disease.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11074-11079
    • Shimojo, N.1
  • 24
    • 0032915936 scopus 로고    scopus 로고
    • Regulation and transfer of a murine model of thyrotropin receptor antibody mediated Graves' disease
    • Kita, M. et al. Regulation and transfer of a murine model of thyrotropin receptor antibody mediated Graves' disease. Endocrinology 140, 1392-1398 (1999).
    • (1999) Endocrinology , vol.140 , pp. 1392-1398
    • Kita, M.1
  • 25
    • 0034027425 scopus 로고    scopus 로고
    • Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease
    • Costagliola, S. et al. Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease. J. Clin. Invest. 105, 803-811 (2000). Description of a new model of Graves' disease that shows lymphocytic infiltration and ophthalmopathy.
    • (2000) J. Clin. Invest. , vol.105 , pp. 803-811
    • Costagliola, S.1
  • 26
    • 0030748379 scopus 로고    scopus 로고
    • Development of spontaneous autoimmune thyroiditis in Obese strain (OS) chickens
    • Dietrich, H. M., Oliveira-dos-Santos, A. J. & Wick, G. Development of spontaneous autoimmune thyroiditis in Obese strain (OS) chickens. Vet. Immunol. Immunopathol. 57, 141-146 (1997),
    • (1997) Vet. Immunol. Immunopathol. , vol.57 , pp. 141-146
    • Dietrich, H.M.1    Oliveira-dos-Santos, A.J.2    Wick, G.3
  • 27
    • 0020822681 scopus 로고
    • Spontaneous thyroiditis in BB Wistar diabetic rats
    • Wright, J. R., Jr, Senhauser, D. A., Yates, A. J., Sharma, H. M. & Thibert, P. Spontaneous thyroiditis in BB Wistar diabetic rats. Vet. Pathol. 20, 522-530 (1983). Description of a spontaneous model of autoimmune thyroiditis in mammals.
    • (1983) Vet. Pathol. , vol.20 , pp. 522-530
    • Wright J.R., Jr.1    Senhauser, D.A.2    Yates, A.J.3    Sharma, H.M.4    Thibert, P.5
  • 28
    • 0030561148 scopus 로고    scopus 로고
    • Iodine-induced autoimmune thyroiditis in NOD-H-2h4 mice
    • Rasooly, L., Burek, C. L. & Rose, N. R. Iodine-induced autoimmune thyroiditis in NOD-H-2h4 mice. Clin. Immunol. Immunopathol. 81, 287-292 (1996).
    • (1996) Clin. Immunol. Immunopathol. , vol.81 , pp. 287-292
    • Rasooly, L.1    Burek, C.L.2    Rose, N.R.3
  • 29
    • 0017094553 scopus 로고
    • Autoimmune murine thyroiditis. VIII. Role of different thyroid antigens in the induction of experimental autoimmune thyroiditis
    • Tomazic, V. & Rose, N. R. Autoimmune murine thyroiditis. VIII. Role of different thyroid antigens in the induction of experimental autoimmune thyroiditis. Immunology 30, 63-68 (1976). One of the concluding papers of the initial description of the experimental autoimmune thyroiditis model.
    • (1976) Immunology , vol.30 , pp. 63-68
    • Tomazic, V.1    Rose, N.R.2
  • 30
    • 0023100476 scopus 로고
    • Transfer of experimental autoimmune thyroiditis with T cell clones
    • Romball, C. G. & Weigle, W. O. Transfer of experimental autoimmune thyroiditis with T cell clones. J. Immunol. 138, 1092-1098 (1987). Demonstration that thyroid-specific T-cell clones can transfer autoimmune thyroiditis.
    • (1987) J. Immunol. , vol.138 , pp. 1092-1098
    • Romball, C.G.1    Weigle, W.O.2
  • 31
    • 0023795409 scopus 로고
    • Induction of autoimmunity with dendritic cells: Studies on thyroiditis in mice
    • Knight, S. C. et al. Induction of autoimmunity with dendritic cells: studies on thyroiditis in mice. Clin. Immunol. Immunopathol. 48, 277-289 (1988).
    • (1988) Clin. Immunol. Immunopathol. , vol.48 , pp. 277-289
    • Knight, S.C.1
  • 32
    • 0024460344 scopus 로고
    • - cells by rat monoclonal antibodies alters the development of adoptively transferred experimental autoimmune thyroiditis
    • - cells by rat monoclonal antibodies alters the development of adoptively transferred experimental autoimmune thyroiditis. Cell. Immunol. 122, 377-390 (1989).
    • (1989) Cell. Immunol. , vol.122 , pp. 377-390
    • Flynn, J.C.1    Conaway, D.H.2    Cobbold, S.3    Waldmann, H.4    Kong, Y.C.5
  • 33
    • 0023681664 scopus 로고
    • Phenotypic characteristics of cells involved in induced suppression to murine experimental autoimmune thyroiditis
    • Parish, N. M., Roitt, I. M. & Cooke, A. Phenotypic characteristics of cells involved in induced suppression to murine experimental autoimmune thyroiditis. Eur. J. Immunol. 18, 1463-1477 (1988).
    • (1988) Eur. J. Immunol. , vol.18 , pp. 1463-1477
    • Parish, N.M.1    Roitt, I.M.2    Cooke, A.3
  • 34
    • 0024380403 scopus 로고
    • Experimental autoimmune thyroiditis in mice chronically treated from birth with anti-IgM antibodies
    • Vladutiu, A. O. Experimental autoimmune thyroiditis in mice chronically treated from birth with anti-IgM antibodies Cell. Immunol. 121, 49-59 (1989).
    • (1989) Cell. Immunol. , vol.121 , pp. 49-59
    • Vladutiu, A.O.1
  • 35
    • 0031920939 scopus 로고    scopus 로고
    • Interleukin-12 promotes activation of effector cells that induce a severe destructive granulomatous form of murine experimental autoimmune thyroiditis
    • Braley-Mullen, H. et al. Interleukin-12 promotes activation of effector cells that induce a severe destructive granulomatous form of murine experimental autoimmune thyroiditis, Am. J. Pathol. 152, 1347-1358 (1998). Description of a destructive model of experimental autoimmune thyroiditis.
    • (1998) Am. J. Pathol. , vol.152 , pp. 1347-1358
    • Braley-Mullen, H.1
  • 36
    • 0017712227 scopus 로고
    • Immune complex deposits in Graves' disease and Hashimoto's thyroiditis
    • Kalderon, A. E. & Bogaars, H. A. Immune complex deposits in Graves' disease and Hashimoto's thyroiditis Am. J. Med. 63, 729-734 (1977). First demonstration of immune-complex deposits in thyroid autoimmunity.
    • (1977) Am. J. Med. , vol.63 , pp. 729-734
    • Kalderon, A.E.1    Bogaars, H.A.2
  • 37
    • 0024410181 scopus 로고
    • Terminal complement complexes and C1/C1 inhibitor complexes in autoimmune thyroid disease
    • Weetman, A. P., Cohen, S. B., Oleesky, D. A. & Morgan, B. P. Terminal complement complexes and C1/C1 inhibitor complexes in autoimmune thyroid disease. Clin. Exp. Immunol. 77, 25-30 (1989).
    • (1989) Clin. Exp. Immunol. , vol.77 , pp. 25-30
    • Weetman, A.P.1    Cohen, S.B.2    Oleesky, D.A.3    Morgan, B.P.4
  • 38
    • 0019401030 scopus 로고
    • Presence of the organ-specific 'microsomal' autoantigen on the surface of human thyroid cells in culture: Its involvement in complement-mediated cytotoxicity
    • Khoury, E. L., Hammond, L., Bottazzo, G. F. & Doniach, D. Presence of the organ-specific 'microsomal' autoantigen on the surface of human thyroid cells in culture: its involvement in complement-mediated cytotoxicity. Clin. Exp. Immunol. 45, 316-328 (1981).
    • (1981) Clin. Exp. Immunol. , vol.45 , pp. 316-328
    • Khoury, E.L.1    Hammond, L.2    Bottazzo, G.F.3    Doniach, D.4
  • 39
    • 0021211312 scopus 로고
    • Antibody-dependent cell mediated cytotoxicity against human thyroid cells in Hashimoto's thyroiditis but not Graves' disease
    • Bogner, U., Schleusener, H. & Wail, J. R. Antibody-dependent cell mediated cytotoxicity against human thyroid cells in Hashimoto's thyroiditis but not Graves' disease. J. Clin. Endocrinol. Metab. 59, 734-738 (1984).
    • (1984) J. Clin. Endocrinol. Metab. , vol.59 , pp. 734-738
    • Bogner, U.1    Schleusener, H.2    Wail, J.R.3
  • 40
    • 0031029105 scopus 로고    scopus 로고
    • Recombinant thyroid peroxidase-specific Fab converted to immunoglobulin G (IgG) molecules: Evidence for thyroid cell damage by IgG1, but not IgG4, autoantibodies
    • Guo, J., Jaurne, J. C., Rapoport, B. & McLachlan, S. M. Recombinant thyroid peroxidase-specific Fab converted to immunoglobulin G (IgG) molecules: evidence for thyroid cell damage by IgG1, but not IgG4, autoantibodies. J. Clin. Endocrinol. Metab. 82, 925-931 (1997).
    • (1997) J. Clin. Endocrinol. Metab. , vol.82 , pp. 925-931
    • Guo, J.1    Jaurne, J.C.2    Rapoport, B.3    McLachlan, S.M.4
  • 41
    • 0026757485 scopus 로고
    • Antithyroid drugs and release of inflammatory mediators by complement-attacked thyroid cells
    • Weetman, A. P., Tandon, N. & Morgan. B. P. Antithyroid drugs and release of inflammatory mediators by complement-attacked thyroid cells. Lancet 340, 633-636 (1992).
    • (1992) Lancet , vol.340 , pp. 633-636
    • Weetman, A.P.1    Tandon, N.2    Morgan, B.P.3
  • 42
    • 0028110928 scopus 로고
    • Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity
    • Kagi, D. et al. Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity. Science 265, 528-530 (1994).
    • (1994) Science , vol.265 , pp. 528-530
    • Kagi, D.1
  • 43
    • 0027937745 scopus 로고
    • Cytolytic T-cell cytotoxicity is mediated through perforin and Fas Iytic pathways
    • Lowin, B., Hahne, M., Mattmann. C. & Tschopp, J. Cytolytic T-cell cytotoxicity is mediated through perforin and Fas Iytic pathways. Nature 370, 650-652 (1994). References 42 and 43 were the first to show that both perforin and death-receptor pathways mediate T-cell cytotoxicity.
    • (1994) Nature , vol.370 , pp. 650-652
    • Lowin, B.1    Hahne, M.2    Mattmann, C.3    Tschopp, J.4
  • 44
    • 0029099845 scopus 로고
    • Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B
    • Darmon, A. J., Nicholson, D. W. & Bleackley, R. C. Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B. Nature 377, 446-468 (1995). The first demonstration that granzyme B activates the apoptotic caspase cascade.
    • (1995) Nature , vol.377 , pp. 446-468
    • Darmon, A.J.1    Nicholson, D.W.2    Bleackley, R.C.3
  • 45
    • 0030849093 scopus 로고    scopus 로고
    • A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
    • Thornberry, N. A. et al. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. J. Biol. Chem. 272, 17907-17911 (1997).
    • (1997) J. Biol. Chem. , vol.272 , pp. 17907-17911
    • Thornberry, N.A.1
  • 46
    • 0028114746 scopus 로고
    • Perforin expression by thyroid-infiltrating T cells in autoimmune thyroid disease
    • Wu, Z., Podack, E. R., McKenzie, J. M., Olsen, K. J. & Zakarija, M. Perforin expression by thyroid-infiltrating T cells in autoimmune thyroid disease. Clin. Exp. Immunol. 98, 470-477 (1994).
    • (1994) Clin. Exp. Immunol. , vol.98 , pp. 470-477
    • Wu, Z.1    Podack, E.R.2    McKenzie, J.M.3    Olsen, K.J.4    Zakarija, M.5
  • 47
    • 0020570297 scopus 로고
    • Lectin-induced expression of DR antigen on human cultured follicular thyroid cells
    • Pujol-Borrell, R., Hanafusa, T., Chiovato, L. & Bottazzo, G. F. Lectin-induced expression of DR antigen on human cultured follicular thyroid cells. Nature 304, 71-73 (1983).
    • (1983) Nature , vol.304 , pp. 71-73
    • Pujol-Borrell, R.1    Hanafusa, T.2    Chiovato, L.3    Bottazzo, G.F.4
  • 48
    • 0021716298 scopus 로고
    • Epithelial cells expressing aberrant MHC class II determinants can present antigen to cloned human T cells
    • Londei, M., Lamb, J. R., Bottazzo, G. F. & Feldmann, M. Epithelial cells expressing aberrant MHC class II determinants can present antigen to cloned human T cells. Nature 312, 639-641 (1984). References 47 and 48 were the first to show that thyrocytes can express MHC class II molecules and act as antigen-presenting cells.
    • (1984) Nature , vol.312 , pp. 639-641
    • Londei, M.1    Lamb, J.R.2    Bottazzo, G.F.3    Feldmann, M.4
  • 49
    • 0023280401 scopus 로고
    • An intrathyroidal T-cell clone specifically cytotoxic for human thyroid cells
    • Mackenzie, W. A. & Davies, T. F. An intrathyroidal T-cell clone specifically cytotoxic for human thyroid cells. Immunology. 61, 101-103 (1987).
    • (1987) Immunology , vol.61 , pp. 101-103
    • Mackenzie, W.A.1    Davies, T.F.2
  • 50
    • 0023112983 scopus 로고
    • Intrathyroidal T cell clones from patients with autoimmune thyroid disease
    • MacKenzie, W. A., Schwartz, A. E., Friedman, E. W. & Davies, T. F. Intrathyroidal T cell clones from patients with autoimmune thyroid disease. J. Clin. Endocrinol. Metab. 64, 818-824 (1987). References 49 and 50 describe T-cell clones that are selectively cytotoxic to autologous thyroid cells.
    • (1987) J. Clin. Endocrinol. Metab. , vol.64 , pp. 818-824
    • MacKenzie, W.A.1    Schwartz, A.E.2    Friedman, E.W.3    Davies, T.F.4
  • 51
    • 0029143849 scopus 로고
    • + T cell lines/clones derived from autoimmune thyroiditis lesions. They recognize self-thyroid antigens directly on TEC to exhibit T helper cell 1-type lymphokine production and cytotoxicity against TEC
    • + T cell lines/clones derived from autoimmune thyroiditis lesions. They recognize self-thyroid antigens directly on TEC to exhibit T helper cell 1-type lymphokine production and cytotoxicity against TEC. J. Immunol. 155, 1619-1628 (1995).
    • (1995) J. Immunol. , vol.155 , pp. 1619-1628
    • Sugihara, S.1    Fujiwara, H.2    Niimi, H.3    Shearer, G.M.4
  • 52
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner, M. O. The biochemistry of apoptosis. Nature 407, 770-776 (2000).
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 53
    • 0035146929 scopus 로고    scopus 로고
    • Life-or-death decisions by the Bcl-2 protein family
    • Adams, J. M. & Cory, S. Life-or-death decisions by the Bcl-2 protein family. Trends Biochem. Sci. 26, 61-66 (2001).
    • (2001) Trends Biochem. Sci. , vol.26 , pp. 61-66
    • Adams, J.M.1    Cory, S.2
  • 54
    • 0030782387 scopus 로고    scopus 로고
    • Fas (APO-1, CD95)-mediated apoptosis in thyroid cells is regulated by a labile protein inhibitor
    • Arscott, P. L. et al. Fas (APO-1, CD95)-mediated apoptosis in thyroid cells is regulated by a labile protein inhibitor. Endocrinology 138, 5019-5027 (1997).
    • (1997) Endocrinology , vol.138 , pp. 5019-5027
    • Arscott, P.L.1
  • 55
    • 0030731917 scopus 로고    scopus 로고
    • Nitric oxide primes pancreatic β cells for Fas-mediated destruction in insulin-dependent diabetes mellitus
    • Stassi, G. et al. Nitric oxide primes pancreatic β cells for Fas-mediated destruction in insulin-dependent diabetes mellitus J. Exp. Med 186, 1193-1200 (1997). Describes a new pathway that is responsible for autoimmune β-cell destruction in human diabetes.
    • (1997) J. Exp. Med. , vol.186 , pp. 1193-1200
    • Stassi, G.1
  • 56
    • 0033486001 scopus 로고    scopus 로고
    • Immune (dys)regulation in multiple sclerosis: Role of the CD95-CD95 ligand system
    • Zipp, F., Krammer, P. H. & Weller, M. Immune (dys)regulation in multiple sclerosis: role of the CD95-CD95 ligand system. Immunol. Today 20, 550-554 (1999).
    • (1999) Immunol. Today , vol.20 , pp. 550-554
    • Zipp, F.1    Krammer, P.H.2    Weller, M.3
  • 57
    • 0032821034 scopus 로고    scopus 로고
    • The role of Fas-mediated apoptosis in thyroid autoimmune disease
    • Borgerson, K. L., Bretz, J. D. & Baker. J. R. Jr. The role of Fas-mediated apoptosis in thyroid autoimmune disease Autoimmunity 30, 251-264 (1999).
    • (1999) Autoimmunity , vol.30 , pp. 251-264
    • Borgerson, K.L.1    Bretz, J.D.2    Baker J.R., Jr.3
  • 58
    • 0027420929 scopus 로고
    • Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells
    • Leithauser F. et al. Constitutive and induced expression of APO-1, a new member of the nerve growth factor/tumor necrosis factor receptor superfamily, in normal and neoplastic cells Lab, Invest. 69, 415-429 (1993). An extensive analysis of CD95 expression in human tissues.
    • (1993) Lab. Invest. , vol.69 , pp. 415-429
    • Leithauser, F.1
  • 59
    • 0003211330 scopus 로고    scopus 로고
    • Constitutive expression of FasL in thyrocytes
    • Stokes, T. A. et al. Constitutive expression of FasL in thyrocytes. Science 279. 2015A (1998).
    • (1998) Science , vol.279
    • Stokes, T.A.1
  • 60
    • 0035287414 scopus 로고    scopus 로고
    • Response to 'Thyrocytes - Not innocent bystanders in autoimmune disease'
    • Stassi, G. & De Maria, R. Response to 'Thyrocytes - not innocent bystanders in autoimmune disease'. Nature Immunol. 2, 183 (2001).
    • (2001) Nature Immunol. , vol.2 , pp. 183
    • Stassi, G.1    De Maria, R.2
  • 61
    • 0030872479 scopus 로고    scopus 로고
    • Analysis of apoptosis in relation to tissue destruction associated with Hashimoto's autoimmune thyroiditis
    • Hammond, L. J. et al. Analysis of apoptosis in relation to tissue destruction associated with Hashimoto's autoimmune thyroiditis. J. Pathol. 182, 138-144 (1997).
    • (1997) J. Pathol. , vol.182 , pp. 138-144
    • Hammond, L.J.1
  • 62
    • 0031790839 scopus 로고    scopus 로고
    • Fas/Fas ligand up-regulation and Bcl-2 down-regulation may be significant in the pathogenesis of Hashimoto's thyroiditis
    • Mitsiades, N. et al Fas/Fas ligand up-regulation and Bcl-2 down-regulation may be significant in the pathogenesis of Hashimoto's thyroiditis. J. Clin. Endocrinol. Metab. 83, 2199-2203 (1998).
    • (1998) J. Clin. Endocrinol. Metab. , vol.83 , pp. 2199-2203
    • Mitsiades, N.1
  • 63
    • 0032910885 scopus 로고    scopus 로고
    • Gene therapy of experimental autoimmune thyroiditis by in vivo administration of plasmid DNA coding for Fas ligand
    • Batteux, F., Tourneur, L., Trebeden, H., Charreire, J. & Chiocchia, G. Gene therapy of experimental autoimmune thyroiditis by in vivo administration of plasmid DNA coding for Fas ligand. J. Immunol 162, 603-608 (1999).
    • (1999) J. Immunol. , vol.162 , pp. 603-608
    • Batteux, F.1    Tourneur, L.2    Trebeden, H.3    Charreire, J.4    Chiocchia, G.5
  • 64
    • 0034651608 scopus 로고    scopus 로고
    • Transgenic expression of Fas ligand on thyroid follicular cells prevents autoimmune thyroiditis
    • Batteux, F., Lores, P., Bucchini, D. & Chiocchia, G. Transgenic expression of Fas ligand on thyroid follicular cells prevents autoimmune thyroiditis. J. Immunol. 164, 1681-1688 (2000).
    • (2000) J. Immunol. , vol.164 , pp. 1681-1688
    • Batteux, F.1    Lores, P.2    Bucchini, D.3    Chiocchia, G.4
  • 65
    • 0030055347 scopus 로고    scopus 로고
    • Expression of tumour necrosis factor-α (TNF-α) mRNA and protein in pathological thyroid tissue and carcinoma cell lines
    • Aust, G. et al. Expression of tumour necrosis factor-α (TNF-α) mRNA and protein in pathological thyroid tissue and carcinoma cell lines. Clin. Exp. Immunol. 105, 148-154 (1996).
    • (1996) Clin. Exp. Immunol. , vol.105 , pp. 148-154
    • Aust, G.1
  • 66
    • 0033520295 scopus 로고    scopus 로고
    • Inflammatory cytokine regulation of Fas-mediated apoptosis in thyroid follicular cells
    • Bretz, J. D., Arscott, P. L., Myc, A. & Baker, J. R. Jr. Inflammatory cytokine regulation of Fas-mediated apoptosis in thyroid follicular cells. J. Biol. Chem. 274, 25433-25438 (1999).
    • (1999) J. Biol. Chem. , vol.274 , pp. 25433-25438
    • Bretz, J.D.1    Arscott, P.L.2    Myc, A.3    Baker J.R., Jr.4
  • 67
    • 0033551831 scopus 로고    scopus 로고
    • TRAIL death pathway expression and induction in thyroid follicular cells
    • Bretz, J. D. et al. TRAIL death pathway expression and induction in thyroid follicular cells. J. Biol. Chem. 274, 23627-23632 (1999). Demonstration of a new potential pathway for thyrocyte apoptosis.
    • (1999) J. Biol. Chem. , vol.274 , pp. 23627-23632
    • Bretz, J.D.1
  • 68
    • 0035725796 scopus 로고    scopus 로고
    • Apoptosis and autoimmune thyroid disease: Following a TRAIL to thyroid destruction?
    • Bretz, J. D. & Baker, J. R. Jr. Apoptosis and autoimmune thyroid disease: following a TRAIL to thyroid destruction? Clin. Endocrinol. (Oxf) 55, 1-11 (2001).
    • (2001) Clin. Endocrinol. (Oxf) , vol.55 , pp. 1-11
    • Bretz, J.D.1    Baker J.R., Jr.2
  • 69
    • 0029120235 scopus 로고
    • Apoptosis in thyroid tissue from patients with Hashimoto's thyroiditis
    • Kotani, T. et al. Apoptosis in thyroid tissue from patients with Hashimoto's thyroiditis. Autoimmunity 20, 231-236 (1995).
    • (1995) Autoimmunity , vol.20 , pp. 231-236
    • Kotani, T.1
  • 70
    • 0033303663 scopus 로고    scopus 로고
    • Characterization of FAP-1 expression and function in thyroid follicular cells
    • Myc, A., Arscott, P. L., Bretz, J. D., Thompson, N. W. & Baker, J. R. Jr. Characterization of FAP-1 expression and function in thyroid follicular cells. Endocrinology 140, 5431-5434 (1999). A possible explanation for the refractoriness to CD95-induced apoptosis that is observed in normal thyrocytes.
    • (1999) Endocrinology , vol.140 , pp. 5431-5434
    • Myc, A.1    Arscott, P.L.2    Bretz, J.D.3    Thompson, N.W.4    Baker J.R., Jr.5
  • 71
    • 0028879109 scopus 로고
    • Fas ligand-induced apoptosis as a mechanism of immune privilege
    • Griffith, T. S., Brunner, T., Fletcher, S. M., Green, D. R. & Ferguson, T. A. Fas ligand-induced apoptosis as a mechanism of immune privilege. Science 270, 1189-1192 (1995).
    • (1995) Science , vol.270 , pp. 1189-1192
    • Griffith, T.S.1    Brunner, T.2    Fletcher, S.M.3    Green, D.R.4    Ferguson, T.A.5
  • 72
    • 0030821649 scopus 로고    scopus 로고
    • CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival
    • Stuart. R. M. et al. CD95 ligand (FasL)-induced apoptosis is necessary for corneal allograft survival. J. Clin. Invest. 99, 396-402 (1997).
    • (1997) J. Clin. Invest. , vol.99 , pp. 396-402
    • Stuart, R.M.1
  • 73
    • 0032103027 scopus 로고    scopus 로고
    • The Fas counterattack in vivo: Apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas ligand expression by human esophageal carcinoma
    • Bennett, M. W. et al. The Fas counterattack in vivo: apoptotic depletion of tumor-infiltrating lymphocytes associated with Fas ligand expression by human esophageal carcinoma. J. Immunol. 160, 5669-5675 (1998).
    • (1998) J. Immunol. , vol.160 , pp. 5669-5675
    • Bennett, M.W.1
  • 74
    • 10544232277 scopus 로고    scopus 로고
    • Melanoma cell expression of Fas(Apo-1/CD95) ligand: Implications for tumor immune escape
    • Hahne, M. et al. Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape. Science 274, 1363-1366 (1996).
    • (1996) Science , vol.274 , pp. 1363-1366
    • Hahne, M.1
  • 75
    • 0029808372 scopus 로고    scopus 로고
    • The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand
    • O'Connell, J., O'Sullivan, G. C., Collins, J. K. & Shanahan, F. The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand. J. Exp. Med. 184, 1075-1082 (1996).
    • (1996) J. Exp. Med. , vol.184 , pp. 1075-1082
    • O'Connell, J.1    O'Sullivan, G.C.2    Collins, J.K.3    Shanahan, F.4
  • 76
    • 0030972396 scopus 로고    scopus 로고
    • Transgenic expression of CD95 ligand on islet P-cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts
    • Allison, J., Georgiou, H. M., Strasser, A. & Vaux, D. L. Transgenic expression of CD95 ligand on islet P-cells induces a granulocytic infiltration but does not confer immune privilege upon islet allografts. Proc. Natl Acad. Sci. USA 94, 3943-3947 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 3943-3947
    • Allison, J.1    Georgiou, H.M.2    Strasser, A.3    Vaux, D.L.4
  • 77
    • 0034080750 scopus 로고    scopus 로고
    • Not so Fas: Re-evaluating the mechanisms of immune privilege and tumor escape
    • Restifo, N. R. Not so Fas: re-evaluating the mechanisms of immune privilege and tumor escape Nature Med. 6, 493-595 (2000).
    • (2000) Nature Med. , vol.6 , pp. 493-595
    • Restifo, N.R.1
  • 78
    • 0030680119 scopus 로고    scopus 로고
    • Immune response and myoblasts that express Fas ligand
    • Kang, S. M. et al. Immune response and myoblasts that express Fas ligand. Science 278, 1322-1324 (1997).
    • (1997) Science , vol.278 , pp. 1322-1324
    • Kang, S.M.1
  • 79
    • 0035576208 scopus 로고    scopus 로고
    • Expression and regulation of Fas and Fas ligand on thyrocytes and infiltrating cells during induction and resolution of granulomatous experimental autoimmune thyroiditis
    • Wei, Y., Chen, K., Sharp, G. C., Yagita, H. & Braley-Mullen, H. Expression and regulation of Fas and Fas ligand on thyrocytes and infiltrating cells during induction and resolution of granulomatous experimental autoimmune thyroiditis. J. Immunol. 167, 6678-6686 (2001).
    • (2001) J. Immunol. , vol.167 , pp. 6678-6686
    • Wei, Y.1    Chen, K.2    Sharp, G.C.3    Yagita, H.4    Braley-Mullen, H.5
  • 80
    • 0035421771 scopus 로고    scopus 로고
    • Transgenic expression of CD95 ligand on thyroid follicular cells confers immune privilege upon thyroid allografts
    • Tourneur, L. et al. Transgenic expression of CD95 ligand on thyroid follicular cells confers immune privilege upon thyroid allografts J. Immunol. 167, 1338-1346 (2001).
    • (2001) J. Immunol. , vol.167 , pp. 1338-1346
    • Tourneur, L.1
  • 81
    • 0029847368 scopus 로고    scopus 로고
    • Functional diversity of helper T lymphocytes
    • Abbas, A. K., Murphy, K. M. & Sher, A. Functional diversity of helper T lymphocytes. Nature 383, 787-793 (1996).
    • (1996) Nature , vol.383 , pp. 787-793
    • Abbas, A.K.1    Murphy, K.M.2    Sher, A.3
  • 82
    • 0027141832 scopus 로고
    • H2 cells with related peptide specificity: Relative roles of interleukin (IL)-4 and IL·10
    • H2 cells with related peptide specificity: relative roles of interleukin (IL)-4 and IL·10 J. Neuroimmunol. 48, 213-220 (1993).
    • (1993) J. Neuroimmunol. , vol.48 , pp. 213-220
    • Van der Veen, R.C.1    Stohlman, S.A.2
  • 84
    • 0028237673 scopus 로고
    • Intrathyroidal cytokine gene expression profiles in autoimmune thyroiditis
    • Paschke, R., Schuppert, F., Taton, M. & Velu, T. Intrathyroidal cytokine gene expression profiles in autoimmune thyroiditis. J. Endocrinol. 141, 309-315 (1994).
    • (1994) J. Endocrinol. , vol.141 , pp. 309-315
    • Paschke, R.1    Schuppert, F.2    Taton, M.3    Velu, T.4
  • 85
    • 0029923832 scopus 로고    scopus 로고
    • Different cytokine mRNA profiles in Graves' disease, Hashimoto's thyroiditis, and nonautoimmune thyroid disorders determined by quantitative reverse transcriptase polymerase chain reaction (RT-PCR)
    • Heuer, M., Aust, G., Ode-Hakim, S. & Scherbaum, W. A. Different cytokine mRNA profiles in Graves' disease, Hashimoto's thyroiditis, and nonautoimmune thyroid disorders determined by quantitative reverse transcriptase polymerase chain reaction (RT-PCR). Thyroid 6, 97-106 (1996).
    • (1996) Thyroid , vol.6 , pp. 97-106
    • Heuer, M.1    Aust, G.2    Ode-Hakim, S.3    Scherbaum, W.A.4
  • 86
    • 2642699935 scopus 로고    scopus 로고
    • Single-cell analysis of intrathyroidal lymphocytes shows differential cytokine expression in Hashimoto's and Graves' disease Eur
    • Roura-Mir, C. et al. Single-cell analysis of intrathyroidal lymphocytes shows differential cytokine expression in Hashimoto's and Graves' disease Eur. J. Immunol. 27, 3290-3302 (1997). The first analysis of cytokine production at a single-cell level in activated T cells that infiltrate the thyroid.
    • (1997) J. Immunol. , vol.27 , pp. 3290-3302
    • Roura-Mir, C.1
  • 87
    • 0031021563 scopus 로고    scopus 로고
    • Antigen presentation by interferon-γ-treated thyroid follicular cells inhibits interleukin-2 (IL-2) and supports IL-4 production by B7-dependent human T cells
    • Lombardi. G. et al. Antigen presentation by interferon-γ-treated thyroid follicular cells inhibits interleukin-2 (IL-2) and supports IL-4 production by B7-dependent human T cells. Eur. J. Immunol. 27, 62-71 (1997).
    • (1997) Eur. J. Immunol. , vol.27 , pp. 62-71
    • Lombardi, G.1
  • 88
    • 0028116618 scopus 로고
    • Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease
    • Racke, M. K. et al. Cytokine-induced immune deviation as a therapy for inflammatory autoimmune disease. J. Exp. Med. 180, 1961-1966 (1994).
    • (1994) J. Exp. Med. , vol.180 , pp. 1961-1966
    • Racke, M.K.1
  • 89
    • 0031964338 scopus 로고    scopus 로고
    • Interleukin 10 secretion and impaired effector function of major histocompatibility complex class II-restricted T cells anergized in vivo
    • Buer, J. et al. Interleukin 10 secretion and impaired effector function of major histocompatibility complex class II-restricted T cells anergized in vivo. J. Exp. Med. 187, 177-183 (1998).
    • (1998) J. Exp. Med. , vol.187 , pp. 177-183
    • Buer, J.1
  • 91
    • 0026510069 scopus 로고
    • Interleukin-10 (IL-10) inhibits the induction of nitric oxide synthase by interferon-γ in murine macrophages
    • Cunha, F. Q., Moncada, S. & Liew, F. Y. Interleukin-10 (IL-10) inhibits the induction of nitric oxide synthase by interferon-γ in murine macrophages Biochem. Biophys. Res. Commun. 182, 1155-1159 (1992).
    • (1992) Biochem. Biophys. Res. Commun. , vol.182 , pp. 1155-1159
    • Cunha, F.Q.1    Moncada, S.2    Liew, F.Y.3
  • 92
    • 0032982863 scopus 로고    scopus 로고
    • Curative treatment of experimental autoimmune thyroiditis by in vivo administration of plasmid DNA coding for interleukin-10
    • Batteux, F., Trebeden, H., Charreire, J. & Chiocchia, G. Curative treatment of experimental autoimmune thyroiditis by in vivo administration of plasmid DNA coding for interleukin-10. Eur. J. Immunol. 29. 958-963 (1999).
    • (1999) Eur. J. Immunol. , vol.29 , pp. 958-963
    • Batteux, F.1    Trebeden, H.2    Charreire, J.3    Chiocchia, G.4
  • 93
    • 0033523607 scopus 로고    scopus 로고
    • An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation
    • Asseman, C., Mauze, S., Leach, M. W., Coffman, R. L. & Powrie, F. An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation. J. Exp. Med. 190, 995-1004 (1999).
    • (1999) J. Exp. Med. , vol.190 , pp. 995-1004
    • Asseman, C.1    Mauze, S.2    Leach, M.W.3    Coffman, R.L.4    Powrie, F.5
  • 94
    • 0029941662 scopus 로고    scopus 로고
    • Thyroid-stimulating hormone inhibits Fas antigen-mediated apoptosis of human thyrocytes in vitro
    • Kawakami, A. et al. Thyroid-stimulating hormone inhibits Fas antigen-mediated apoptosis of human thyrocytes in vitro. Endocrinology 137, 3163-3169 (1996).
    • (1996) Endocrinology , vol.137 , pp. 3163-3169
    • Kawakami, A.1
  • 95
    • 0033305305 scopus 로고    scopus 로고
    • Immunohistochemical analysis of Bcl-2, Bax, and Bak expression in thyroid glands from patients with subacute thyroiditis
    • Koga, M. et al. Immunohistochemical analysis of Bcl-2, Bax, and Bak expression in thyroid glands from patients with subacute thyroiditis. J. Clin. Endocrinol. Metab. 84, 2221-2225 (1999).
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 2221-2225
    • Koga, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.