More hypothyroidism and less hyperthyroidism with sufficient iodine nutrition compared to mild iodine deficiency-A comparative population-based study of older people

Maturitas

Volumn 64, Issue 2, 2009, Pages 126-131

  Andersen, Stig ^a   Iversen, Finn ^b   Terpling, Steen ^b   Pedersen, Klaus Michael ^a   Gustenhoff, Peter ^a   Laurberg, Peter ^a  

^a AALBORG UNIVERSITY HOSPITAL   (Denmark)

^b Vensyssel Hospital   (Denmark)

Author keywords

Geriatric population based study; Goiter; Iodine intake; Tap water; Thyroglobulin; Thyroid antibodies; Thyroid disease

Indexed keywords

CREATININE; IODINE; LIOTHYRONINE; TAP WATER; THYROGLOBULIN; THYROGLOBULIN ANTIBODY; THYROID PEROXIDASE ANTIBODY; THYROTROPIN; THYROXINE;

AGED; ARTICLE; AUTOIMMUNE THYROIDITIS; BLOOD ANALYSIS; CLINICAL EXAMINATION; CREATININE URINE LEVEL; CROSS-SECTIONAL STUDY; DENMARK; DIETARY INTAKE; DRUG USE; FEMALE; GERIATRIC PATIENT; GOITER; GRAVES DISEASE; HUMAN; HYPERTHYROIDISM; HYPOTHYROIDISM; IODINE DEFICIENCY; LIOTHYRONINE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; NECK; POPULATION RESEARCH; QUESTIONNAIRE; THYROGLOBULIN BLOOD LEVEL; THYROID FUNCTION TEST; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; URINALYSIS; URINARY EXCRETION; VITAMIN SUPPLEMENTATION;

AGED; AGED, 80 AND OVER; ANTIBODIES; CROSS-SECTIONAL STUDIES; DENMARK; FEMALE; GERIATRIC ASSESSMENT; HUMANS; IODINE; MALE; NUTRITIONAL REQUIREMENTS; REFERENCE VALUES; THYROID DISEASES; THYROTROPIN; WATER; WATER SUPPLY;

EID: 70349728782     PISSN: 03785122     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.maturitas.2009.08.007     Document Type: Article

References (37)

1. Delange F. The disorders induced by iodine deficiency. Thyroid 4 (1994) 107-128
2. Knudsen N., Bülow I., Jørgensen T., Laurberg P., Ovesen L., and Perrild H. Comparative study of thyroid function and types of thyroid dysfunctions in two areas in Denmark with slightly different iodine status. Eur J Endocrinol 143 (2000) 485-491
3. Bülow Pedersen I., Knudsen N., Jorgensen T., Perrild H., Ovesen L., and Laurberg P. Large differences in incidences of overt hyper- and hypothyroidism associated with a small difference in iodine intake: a prospective comparative register-based population survey. J Clin Endocrinol Metab 87 (2002) 4462-4469
4. Konno N., Makita H., Yuri K., Iizuka N., and Kawasaki K. Association between dietary iodine intake and prevalence of subclinical hypothyroidism in the coastal regions of Japan. J Clin Endocrinol Metab 78 (1994) 393-397
5. Laurberg P., Pedersen K.M., Vestergaard H., and Sigurdsson G. High incidence of multinodular toxic goiter in the elderly population in a low iodine intake area vs. high incidence of Graves' disease in the young in a high iodine intake area: comparative surveys of thyrotoxicosis epidemiology in East-Jutland Denmark and Iceland. J Intern Med 229 (1991) 415-420
6. Teng W., Shan Z., Teng X., et al. Effect of iodine intake on thyroid diseases in China. N Engl J Med 354 (2006) 2783-2793
7. Laurberg P., Bulow Pedersen I., Knudsen N., Ovesen L., and Andersen S. Environmental iodine intake affects the type of non-malignant thyroid disease. Thyroid 11 (2001) 457-469
8. World Health Organization. Assessment of iodine deficiency disorders and monitoring their elimination. A guide for programme managers. 3rd ed. (2007), WHO, Geneva
9. Andersen S., Hvingel B., Kleinschmidt K., Jørgensen T., and Laurbeg P. Changes in iodine excretion in 50-69-y-old denizens of an Arctic society in transition and iodine excretion as a biomarker of the frequency of consumption of traditional Inuit foods. Am J Clin Nutr 81 (2005) 656-663
10. Rasmussen L.B., Ovesen L., Bülow I., et al. Dietary iodine intake and urinary iodine excretion in a Danish population. Br J Nutr 87 (2002) 61-69
11. Pedersen K.M., Laurberg P., Nøhr S., Jørgensen A., and Andersen S. Iodine in drinking water varies by more than 100-fold in Denmark. Importance for iodine content of infant formulas. Eur J Endocrinol 140 (1999) 400-403
12. Andersen S., Petersen S.B., and Laurberg P. Iodine in drinking water in Denmark is bound in humic substances. Eur J Endocrinol 147 (2002) 663-670
13. Andersen S., Pedersen K.M., Iversen F., et al. Naturally occurring iodine in humic substances in drinking water is bioavailable and determines population iodine intake. Br J Nutr 99 (2008) 319-325
14. Pedersen K.M., and Laurberg P. Urinary iodine excretion and individual iodine supplementation among elderly subjects: a cross-sectional investigation in the commune of Randers, Denmark. Eur J Endocrinol 132 (1995) 171-174
15. Laurberg P., Jørgensen T., Perrild H., et al. The Danish investigation on iodine intake and thyroid disease, DanThyr: status and perspectives. Eur J Endocrinol 155 (2006) 219-228
16. Wilson B., and van Zyl A. The estimation of iodine in thyroidal amino acids by alkaline ashing. S African J Med Sci 32 (1967) 70-82
17. Laurberg P. Thyroxine and 3,5,3′-triiodothyronine content of thyroglobulin in thyroid needle aspirates in hyperthyroidism and hypothyroidism. J Clin Endocrinol Metab 64 (1987) 969-974
18. Bartels H., Bohmer M., and Heierli C. Serum creatinine determination without protein precipitation. Clin Chim Acta 37 (1972) 193-197
19. Knudsen N., Christiansen E., Brandt-Christensen M., Nygaard B., and Perrild H. Age- and sex-adjusted iodine/creatinine ratio. A new standard in epidemiological surveys? Evaluation of three different estimates of iodine excretion based on casual urine samples and comparison to 24 h values. Eur J Clin Nutr 54 (2000) 361-363
20. Andersen S., Karmisholt J., and Laurberg P. Variations in iodine excretion in healthy individuals. In: Preedy V.R., Burrow G.N., and Watson R. (Eds). Comprehensive Handbook of Iodine. 1st ed. (2009), Academic Press, Oxford 421-428
21. Pedersen I.B., Knudsen N., Jørgensen T., Perrild H., Ovesen L., and Laurberg P. Thyroid peroxidase and thyroglobulin autoantibodies in a large survey of populations with mild and moderate iodine deficiency. Clin Endocrinol 58 (2003) 36-42
22. Tunbridge W.M.G., Evered D.C., Hall R., et al. The spectrum of thyroid disease in the community: the Whickham Survey. Clin Endocrinol 7 (1977) 481-493
23. Hollowell J.G., Staehling N.W., Flanders W.D., et al. Serum TSH, T4, and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). J Clin Endocrinol Metab 87 (2002) 489-499
24. O'Leary P.C., Feddema P.H., Michelangeli V.P., et al. Investigations of thyroid hormones and antibodies based on a community health survey: the Busselton thyroid study. Clin Endocrinol 64 (2006) 97-104
25. Canaris G.J., Manowitz N.R., Mayor G., and Ridgway E.C. The Colorado thyroid disease prevalence study. Arch Intern Med 160 (2000) 526-534
26. Andersen-Ranberg K., Jeune B., Hoier-Madsen M., and Hegedüs L. Thyroid function, morphology and prevalence of thyroid disease in a population-based study of Danish centenarians. J Am Geriatr Soc 47 (1999) 1238-1243
27. Magri F., Muzzoni B., Cravello L., et al. Thyroid function in physiological aging and in centenarians: possible relationship with some nutritional markers. Metabolism 51 (2002) 105-109
28. Hintze G., Burghardt U., Baumert J., Windeler J., and Köbbeling J. Prevalence of thyroid dysfunction in elderly subjects from the general population in an iodine deficiency area. Aging 3 (1991) 325-331
29. Andersen S., Karmisholt J., Pedersen K.M., and Laurberg P. Reliability of studies of iodine intake and recommendations for number of samples in groups and in individuals. Br J Nutr 99 (2008) 813-818
30. Ceresini G., Lauretani F., Maggio M., et al. Thyroid function abnormalities and cognitive impairment in elderly people: results of the invecchiare in Chianti study. J Am Geriatr Soc 57 (2009) 89-93
31. Pedersen I.B., Laurberg P., Knudsen N., et al. An increased incidence of overt hypothyroidism after iodine fortification of salt in Denmark: a prospective population study. J Clin Endocrinol Metab 92 (2007) 3122-3127
32. Szabolcs I., Podoba J., Feldkamp J., et al. Comparative screening for thyroid disorders in old age in areas of iodine deficiency, long-term iodine prophylaxis and abundant iodine intake. Clin Endocrinol 47 (1997) 87-92
33. Feldt-Rasmussen U., Hegedüs L., Perrild H., Rasmussen N., and Hansen J.M. Relationship between serum thyroglobulin, thyroid volume and serum TSH in healthy non-goitrous subjects and the relationship to seasonal variations in iodine intake. Thyroidology 1 (1989) 115-118
34. Knudsen N., Bülow I., Jørgensen T., Perrild H., Ovesen L., and Laurberg P. Serum Tg-a sensitive marker of thyroid abnormalities and iodine deficiency in epidemiological studies. J Clin Endocrinol Metab 86 (2001) 3599-3603
35. Knudsen N., Bülow I., Laurberg P., Perrild H., Ovesen L., and Laurberg P. Alcohol consumption is associated with reduced prevalence of goitre and solitary thyroid nodules. Clin Endocrinol 55 (2001) 41-46
36. Vestergaard P. Smoking and thyroid disorders-a meta-analysis. Eur J Endocrinol 146 (2002) 153-161
37. Vejbjerg P., Knudsen N., Perrild H., et al. Effect of mandatory iodization program on thyroid gland volume based on individuals' age, gender and preceding severity of dietary iodine deficiency: a prospective, population based study. J Clin Endocrinol Metab 92 (2007) 1397-1401