-
1
-
-
60149088848
-
Origins and mechanisms of miRNAs and siRNAs
-
R.W. Carthew, and E.J. Sontheimer Origins and mechanisms of miRNAs and siRNAs Cell 136 2009 642 655
-
(2009)
Cell
, vol.136
, pp. 642-655
-
-
Carthew, R.W.1
Sontheimer, E.J.2
-
2
-
-
58549084364
-
Antisense makes sense in engineered regenerative medicine
-
Y. Yao, C. Wang, R.R. Varshney, and D.A. Wang Antisense makes sense in engineered regenerative medicine Pharm. Res. 26 2009 263 275
-
(2009)
Pharm. Res.
, vol.26
, pp. 263-275
-
-
Yao, Y.1
Wang, C.2
Varshney, R.R.3
Wang, D.A.4
-
3
-
-
77956667224
-
Selective gene silencing by viral delivery of short hairpin RNA
-
K. Sliva, and B.S. Schnierle Selective gene silencing by viral delivery of short hairpin RNA Virology 7 2010 248
-
(2010)
Virology
, vol.7
, pp. 248
-
-
Sliva, K.1
Schnierle, B.S.2
-
4
-
-
31544456413
-
Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging
-
D.W. Bartlett, and M.E. Davis Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging Nucleic Acids Res. 34 2006 322 333
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 322-333
-
-
Bartlett, D.W.1
Davis, M.E.2
-
5
-
-
33645148088
-
The silent treatment: SiRNAs as small molecule drugs
-
D.M. Dykxhoorn, D. Palliser, and J. Lieberman The silent treatment: SiRNAs as small molecule drugs Gene Ther. 13 2006 541 552
-
(2006)
Gene Ther.
, vol.13
, pp. 541-552
-
-
Dykxhoorn, D.M.1
Palliser, D.2
Lieberman, J.3
-
6
-
-
84904544984
-
Non-viral vectors for gene-based therapy
-
H. Yin, R.L. Kanasty, A.A. Eltoukhy, A.J. Vegas, J.R. Dorkin, and D.G. Anderson Non-viral vectors for gene-based therapy Nat. Rev. Gen. 15 2014 541 555
-
(2014)
Nat. Rev. Gen.
, vol.15
, pp. 541-555
-
-
Yin, H.1
Kanasty, R.L.2
Eltoukhy, A.A.3
Vegas, A.J.4
Dorkin, J.R.5
Anderson, D.G.6
-
7
-
-
84883118140
-
Safety and efficacy of RNAi therapy for transthyretin amyloidosis
-
T. Coelho, D. Adams, A. Silva, P. Lozeron, P.N. Hawkins, T. Mant, J. Perez, J. Chiesa, S. Warrington, E. Tranter, M. Munisamy, R. Falzone, J. Harrop, J. Cehelsky, B.R. Bettencourt, M. Geissler, J.S. Butler, A. Sehgal, R.E. Meyers, Q. Chen, T. Borland, R.M. Hutabarat, V.A. Clausen, R. Alvarez, K. Fitzgerald, C. Gamba-Vitalo, S.V. Nochur, A.K. Vaishnaw, D.W. Sah, J.A. Gollob, and O.B. Suhr Safety and efficacy of RNAi therapy for transthyretin amyloidosis New Engl. J. Med. 369 2013 819 829
-
(2013)
New Engl. J. Med.
, vol.369
, pp. 819-829
-
-
Coelho, T.1
Adams, D.2
Silva, A.3
Lozeron, P.4
Hawkins, P.N.5
Mant, T.6
Perez, J.7
Chiesa, J.8
Warrington, S.9
Tranter, E.10
Munisamy, M.11
Falzone, R.12
Harrop, J.13
Cehelsky, J.14
Bettencourt, B.R.15
Geissler, M.16
Butler, J.S.17
Sehgal, A.18
Meyers, R.E.19
Chen, Q.20
Borland, T.21
Hutabarat, R.M.22
Clausen, V.A.23
Alvarez, R.24
Fitzgerald, K.25
Gamba-Vitalo, C.26
Nochur, S.V.27
Vaishnaw, A.K.28
Sah, D.W.29
Gollob, J.A.30
Suhr, O.B.31
more..
-
8
-
-
84908564426
-
Current issues of RNAi therapeutics delivery and development
-
D. Haussecker Current issues of RNAi therapeutics delivery and development J. Control Release 195 2014 49 54
-
(2014)
J. Control Release
, vol.195
, pp. 49-54
-
-
Haussecker, D.1
-
9
-
-
78651388588
-
SiRNA knockdown of ribonucleotide reductase inhibits melanoma cell line proliferation alone or synergistically with temozolomide
-
J.E. Zuckerman, T. Hsueh, R.C. Koya, M.E. Davis, and A. Ribas SiRNA knockdown of ribonucleotide reductase inhibits melanoma cell line proliferation alone or synergistically with temozolomide J. Invest. Dermatol. 131 2011 453 460
-
(2011)
J. Invest. Dermatol.
, vol.131
, pp. 453-460
-
-
Zuckerman, J.E.1
Hsueh, T.2
Koya, R.C.3
Davis, M.E.4
Ribas, A.5
-
10
-
-
84901660512
-
RNAi-mediated silencing of hepatic ALAS1 effectively prevents and treats the induced acute attacks in acute intermittent porphyria mice
-
M. Yasuda, L. Gan, B. Chen, S. Kadirvel, C. Yu, J.D. Phillips, M.I. New, A. Liebow, K. Fitzgerald, W. Querbes, and R.J. Desnick RNAi-mediated silencing of hepatic ALAS1 effectively prevents and treats the induced acute attacks in acute intermittent porphyria mice Proc. Natl. Acad. Sci. U.S.A. 111 2014 7777 7782
-
(2014)
Proc. Natl. Acad. Sci. U.S.A.
, vol.111
, pp. 7777-7782
-
-
Yasuda, M.1
Gan, L.2
Chen, B.3
Kadirvel, S.4
Yu, C.5
Phillips, J.D.6
New, M.I.7
Liebow, A.8
Fitzgerald, K.9
Querbes, W.10
Desnick, R.J.11
-
12
-
-
84867652280
-
The business of RNAi therapeutics in 2012
-
D. Haussecker The business of RNAi therapeutics in 2012 Mol. Ther. Nucleic Acids 1 2012 e8
-
(2012)
Mol. Ther. Nucleic Acids
, vol.1
-
-
Haussecker, D.1
-
13
-
-
84896717533
-
Nanotoxicity: A key obstacle to clinical translation of siRNA-based nanomedicine
-
H.Y. Xue, S. Liu, and H.L. Wong Nanotoxicity: a key obstacle to clinical translation of siRNA-based nanomedicine Nanomed 9 2014 295 312
-
(2014)
Nanomed
, vol.9
, pp. 295-312
-
-
Xue, H.Y.1
Liu, S.2
Wong, H.L.3
-
14
-
-
41649115210
-
Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
-
M.E. Kleinman, K. Yamada, A. Takeda, V. Chandrasekaran, M. Nozaki, J.Z. Baffi, R.J. Albuquerque, S. Yamasaki, M. Itaya, Y. Pan, B. Appukuttan, D. Gibbs, Z. Yang, K. Kariko, B.K. Ambati, T.A. Wilgus, L.A. DiPietro, E. Sakurai, K. Zhang, J.R. Smith, E.W. Taylor, and J. Ambati Sequence- and target-independent angiogenesis suppression by siRNA via TLR3 Nature 452 2008 591 597
-
(2008)
Nature
, vol.452
, pp. 591-597
-
-
Kleinman, M.E.1
Yamada, K.2
Takeda, A.3
Chandrasekaran, V.4
Nozaki, M.5
Baffi, J.Z.6
Albuquerque, R.J.7
Yamasaki, S.8
Itaya, M.9
Pan, Y.10
Appukuttan, B.11
Gibbs, D.12
Yang, Z.13
Kariko, K.14
Ambati, B.K.15
Wilgus, T.A.16
DiPietro, L.A.17
Sakurai, E.18
Zhang, K.19
Smith, J.R.20
Taylor, E.W.21
Ambati, J.22
more..
-
15
-
-
36148997263
-
Modulation of scratching behavior by silencing an endogenous cyclooxygenase-1 gene in the skin through the administration of siRNA
-
T. Inoue, M. Sugimoto, T. Sakurai, R. Saito, N. Futaki, Y. Hashimoto, Y. Honma, I. Arai, and S. Nakaike Modulation of scratching behavior by silencing an endogenous cyclooxygenase-1 gene in the skin through the administration of siRNA J. Gene. Med. 9 2007 994 1001
-
(2007)
J. Gene. Med.
, vol.9
, pp. 994-1001
-
-
Inoue, T.1
Sugimoto, M.2
Sakurai, T.3
Saito, R.4
Futaki, N.5
Hashimoto, Y.6
Honma, Y.7
Arai, I.8
Nakaike, S.9
-
16
-
-
0001359591
-
Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes ín trans
-
C. Napoli, C. Lemieux, and R. Jorgensen Introduction of a chimeric chalcone synthase gene into petunia results in reversible co-suppression of homologous genes ín trans Plant Cell 2 1990
-
(1990)
Plant Cell
, vol.2
-
-
Napoli, C.1
Lemieux, C.2
Jorgensen, R.3
-
17
-
-
0036385852
-
Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo
-
J. Bertrand, M. Pottier, A. Vekris, P. Opolon, A. Maksimenko, and C. Malvy Comparison of antisense oligonucleotides and siRNAs in cell culture and in vivo Biochem. Biophys. Res. Commun. 296 2002
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.296
-
-
Bertrand, J.1
Pottier, M.2
Vekris, A.3
Opolon, P.4
Maksimenko, A.5
Malvy, C.6
-
18
-
-
13844281898
-
Synthetic dsRNA dicer substrates enhance RNAi potency and efficacy
-
D.H. Kim, M.A. Behlke, S.D. Rose, M.S. Chang, S. Choi, and J.J. Rossi Synthetic dsRNA dicer substrates enhance RNAi potency and efficacy Nat. Biotechnol. 23 2005 222 226
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 222-226
-
-
Kim, D.H.1
Behlke, M.A.2
Rose, S.D.3
Chang, M.S.4
Choi, S.5
Rossi, J.J.6
-
19
-
-
0031010177
-
2′-O-(2-methoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells
-
B.F. Baker 2′-O-(2-methoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells J. Biol. Chem. 272 1997 11994 12000
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 11994-12000
-
-
Baker, B.F.1
-
20
-
-
0034673638
-
An RNA-directed nuclease mediates post-transcriptional gene silencing in drosophila cells
-
S.M. Hammond, E. Bernstein, D. Beach, and G.J. Hannon An RNA-directed nuclease mediates post-transcriptional gene silencing in drosophila cells Nature 404 2000
-
(2000)
Nature
, vol.404
-
-
Hammond, S.M.1
Bernstein, E.2
Beach, D.3
Hannon, G.J.4
-
21
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
E. Bernstein, A.A. Caudy, S.M. Hammond, and G.J. Hannon Role for a bidentate ribonuclease in the initiation step of RNA interference Nature 409 2001
-
(2001)
Nature
, vol.409
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
22
-
-
3042602447
-
Kinetic analysis of the RNAi enzyme complex
-
B. Haley, and P.D. Zamore Kinetic analysis of the RNAi enzyme complex Nat. Struct. Biol. 11 2004 599 606
-
(2004)
Nat. Struct. Biol.
, vol.11
, pp. 599-606
-
-
Haley, B.1
Zamore, P.D.2
-
23
-
-
84937515138
-
MiRNA inhibition in tissue engineering and regenerative medicine
-
K.R. Beavers, C.E. Nelson, and C.L. Duvall MiRNA inhibition in tissue engineering and regenerative medicine Adv. Drug Deliv. Rev. 88 2014 123 137
-
(2014)
Adv. Drug Deliv. Rev.
, vol.88
, pp. 123-137
-
-
Beavers, K.R.1
Nelson, C.E.2
Duvall, C.L.3
-
25
-
-
57349134691
-
Chemical modification of siRNAs for in vivo use
-
M.A. Behlke Chemical modification of siRNAs for in vivo use Oligonucleotides 18 2008 305 319
-
(2008)
Oligonucleotides
, vol.18
, pp. 305-319
-
-
Behlke, M.A.1
-
26
-
-
0037031576
-
Single-stranded antisense siRNAs guide target RNA cleavage in RNAi
-
J. Martinez, A. Patkaniowska, H. Urlaub, R. Luhrmann, and T. Tuschl Single-stranded antisense siRNAs guide target RNA cleavage in RNAi Cell 110 2004
-
(2004)
Cell
, vol.110
-
-
Martinez, J.1
Patkaniowska, A.2
Urlaub, H.3
Luhrmann, R.4
Tuschl, T.5
-
27
-
-
84880304273
-
Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape
-
J. Gilleron, W. Querbes, A. Zeigerer, A. Borodovsky, G. Marsico, U. Schubert, K. Manygoats, S. Seifert, C. Andree, M. Stoter, H. Epstein-Barash, L. Zhang, V. Koteliansky, K. Fitzgerald, E. Fava, M. Bickle, Y. Kalaidzidis, A. Akinc, M. Maier, and M. Zerial Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape Nat. Biotechnol. 31 2013 638 646
-
(2013)
Nat. Biotechnol.
, vol.31
, pp. 638-646
-
-
Gilleron, J.1
Querbes, W.2
Zeigerer, A.3
Borodovsky, A.4
Marsico, G.5
Schubert, U.6
Manygoats, K.7
Seifert, S.8
Andree, C.9
Stoter, M.10
Epstein-Barash, H.11
Zhang, L.12
Koteliansky, V.13
Fitzgerald, K.14
Fava, E.15
Bickle, M.16
Kalaidzidis, Y.17
Akinc, A.18
Maier, M.19
Zerial, M.20
more..
-
28
-
-
0035942736
-
Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells
-
S.M. Elbashir, J. Harborth, W. Lendeckel, A. Yalcin, K. Weber, and T. Tuschl Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells Nature 411 2001
-
(2001)
Nature
, vol.411
-
-
Elbashir, S.M.1
Harborth, J.2
Lendeckel, W.3
Yalcin, A.4
Weber, K.5
Tuschl, T.6
-
29
-
-
2442705429
-
Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3
-
K. Kariko, P. Bhuyan, J. Capodici, and D. Weissman Small interfering RNAs mediate sequence-independent gene suppression and induce immune activation by signaling through toll-like receptor 3 J. Immunol. 172 2004 6545 6549
-
(2004)
J. Immunol.
, vol.172
, pp. 6545-6549
-
-
Kariko, K.1
Bhuyan, P.2
Capodici, J.3
Weissman, D.4
-
30
-
-
1542317578
-
Species-specific recognition of single-stranded RNA via Toll-like receptor 7 and 8
-
F. Heil, H. Hemmi, H. Hochrein, F. Ampenberger, C. Kirschning, S. Akira, G. Lipford, H. Wagner, and S. Bauer Species-specific recognition of single-stranded RNA via Toll-like receptor 7 and 8 Science 303 2004
-
(2004)
Science
, vol.303
-
-
Heil, F.1
Hemmi, H.2
Hochrein, H.3
Ampenberger, F.4
Kirschning, C.5
Akira, S.6
Lipford, G.7
Wagner, H.8
Bauer, S.9
-
31
-
-
74049124186
-
Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
-
A.L. Jackson, and P.S. Linsley Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application Nat. Rev. Drug Discov. 9 2010 57 67
-
(2010)
Nat. Rev. Drug Discov.
, vol.9
, pp. 57-67
-
-
Jackson, A.L.1
Linsley, P.S.2
-
32
-
-
84905670761
-
Correlating animal and human phase IA/IB clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA
-
J.E. Zuckerman, I. Gritli, A. Tolcher, J.D. Heidel, D. Lim, R. Morgan, B. Chmielowski, A. Ribas, M.E. Davis, and Y. Yen Correlating animal and human phase IA/IB clinical data with CALAA-01, a targeted, polymer-based nanoparticle containing siRNA Proc. Natl. Acad. Sci. U. S. A. 111 2014 11449 11454
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 11449-11454
-
-
Zuckerman, J.E.1
Gritli, I.2
Tolcher, A.3
Heidel, J.D.4
Lim, D.5
Morgan, R.6
Chmielowski, B.7
Ribas, A.8
Davis, M.E.9
Yen, Y.10
-
33
-
-
12844285548
-
Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs
-
R. Yi, B.P. Doehle, Y. Qin, I.G. Macara, and B.R. Cullen Overexpression of exportin 5 enhances RNA interference mediated by short hairpin RNAs and microRNAs RNA 11 2005 220 226
-
(2005)
RNA
, vol.11
, pp. 220-226
-
-
Yi, R.1
Doehle, B.P.2
Qin, Y.3
Macara, I.G.4
Cullen, B.R.5
-
34
-
-
0037685280
-
Expression profiling reveals off-target gene regulation by RNAi
-
A.L. Jackson, S.R. Bartz, J. Schelter, S.V. Kobayashi, J. Burchard, M. Mao, B. Li, G. Cavet, and P.S. Linsley Expression profiling reveals off-target gene regulation by RNAi Nat. Biotechnol 2003
-
(2003)
Nat. Biotechnol
-
-
Jackson, A.L.1
Bartz, S.R.2
Schelter, J.3
Kobayashi, S.V.4
Burchard, J.5
Mao, M.6
Li, B.7
Cavet, G.8
Linsley, P.S.9
-
35
-
-
84876497020
-
Delivery systems and local administration routes for therapeutic siRNA
-
F.T. Vicentini, L.N. Borgheti-Cardoso, L.V. Depieri, M.D. de Macedo, T.F. Abelha, R. Petrilli, and M.V. Bentley Delivery systems and local administration routes for therapeutic siRNA Pharm. Res. 30 2013 915 931
-
(2013)
Pharm. Res.
, vol.30
, pp. 915-931
-
-
Vicentini, F.T.1
Borgheti-Cardoso, L.N.2
Depieri, L.V.3
De Macedo, M.D.4
Abelha, T.F.5
Petrilli, R.6
Bentley, M.V.7
-
36
-
-
84903390267
-
Modified-chitosan/siRNA nanoparticles downregulate cellular cdx2 expression and cross the gastric mucus barrier
-
A. Sadio, J.K. Gustafsson, B. Pereira, C.P. Gomes, G.C. Hansson, L. David, A.P. Pego, and R. Almeida Modified-chitosan/siRNA nanoparticles downregulate cellular cdx2 expression and cross the gastric mucus barrier PloS One 9 2014
-
(2014)
PloS One
, vol.9
-
-
Sadio, A.1
Gustafsson, J.K.2
Pereira, B.3
Gomes, C.P.4
Hansson, G.C.5
David, L.6
Pego, A.P.7
Almeida, R.8
-
37
-
-
84906784538
-
Controlled release for local delivery of drugs: Barriers and models
-
J.R. Weiser, and W.M. Saltzman Controlled release for local delivery of drugs: barriers and models J. Control Release 190 2014 664 673
-
(2014)
J. Control Release
, vol.190
, pp. 664-673
-
-
Weiser, J.R.1
Saltzman, W.M.2
-
38
-
-
84879691173
-
Durable knockdown and protection from HIV transmission in humanized mice treated with gel-formulated CD4 aptamer-siRNA chimeras
-
L.A. Wheeler, V. Vrbanac, R. Trifonova, M.A. Brehm, A. Gilboa-Geffen, S. Tanno, D.L. Greiner, A.D. Luster, A.M. Tager, and J. Lieberman Durable knockdown and protection from HIV transmission in humanized mice treated with gel-formulated CD4 aptamer-siRNA chimeras Mol. Ther. 21 2013 1378 1389
-
(2013)
Mol. Ther.
, vol.21
, pp. 1378-1389
-
-
Wheeler, L.A.1
Vrbanac, V.2
Trifonova, R.3
Brehm, M.A.4
Gilboa-Geffen, A.5
Tanno, S.6
Greiner, D.L.7
Luster, A.D.8
Tager, A.M.9
Lieberman, J.10
-
39
-
-
84892937899
-
Tunable delivery of siRNA from a biodegradable scaffold to promote angiogenesis in vivo
-
506
-
C.E. Nelson, A.J. Kim, E.J. Adolph, M.K. Gupta, F. Yu, K.M. Hocking, J.M. Davidson, S.A. Guelcher, and C.L. Duvall Tunable delivery of siRNA from a biodegradable scaffold to promote angiogenesis in vivo Adv. Mat. 26 2014 607 614 506
-
(2014)
Adv. Mat.
, vol.26
, pp. 607-614
-
-
Nelson, C.E.1
Kim, A.J.2
Adolph, E.J.3
Gupta, M.K.4
Yu, F.5
Hocking, K.M.6
Davidson, J.M.7
Guelcher, S.A.8
Duvall, C.L.9
-
40
-
-
1942533474
-
In vivo activity of nuclease-resistant siRNAs
-
J.M. Layzer In vivo activity of nuclease-resistant siRNAs RNA 10 2004 766 771
-
(2004)
RNA
, vol.10
, pp. 766-771
-
-
Layzer, J.M.1
-
41
-
-
55849144769
-
Sustained delivery of siRNAs targeting viral infection by cell-degradable multilayered polyelectrolyte films
-
M. Dimitrova, C. Affolter, F. Meyer, I. Nguyen, D.G. Richard, C. Schuster, R. Bartenschlager, J.C. Voegel, J. Ogier, and T.F. Baumert Sustained delivery of siRNAs targeting viral infection by cell-degradable multilayered polyelectrolyte films Proc. Natl. Acad. Sci. U. S. A. 105 2008 16320 16325
-
(2008)
Proc. Natl. Acad. Sci. U. S. A.
, vol.105
, pp. 16320-16325
-
-
Dimitrova, M.1
Affolter, C.2
Meyer, F.3
Nguyen, I.4
Richard, D.G.5
Schuster, C.6
Bartenschlager, R.7
Voegel, J.C.8
Ogier, J.9
Baumert, T.F.10
-
42
-
-
34249947638
-
Matrices and scaffolds for DNA delivery in tissue engineering
-
L.D. Laporte, and L.D. Shea Matrices and scaffolds for DNA delivery in tissue engineering Adv. Drug Deliv. Rev. 59 2007
-
(2007)
Adv. Drug Deliv. Rev.
, vol.59
-
-
Laporte, L.D.1
Shea, L.D.2
-
43
-
-
84862856412
-
Chitosan/siRNA nanoparticles encapsulated in PLGA nanofibers for siRNA delivery
-
M. Chen, S. Gao, M. Dong, J. Song, C. Yang, K.A. Howard, J. Kjems, and F. Besenbacher Chitosan/siRNA nanoparticles encapsulated in PLGA nanofibers for siRNA delivery ACS Nano 6 2012
-
(2012)
ACS Nano
, vol.6
-
-
Chen, M.1
Gao, S.2
Dong, M.3
Song, J.4
Yang, C.5
Howard, K.A.6
Kjems, J.7
Besenbacher, F.8
-
44
-
-
33646176224
-
How porosity and size affect the drug release mechanisms from PLGA-based microparticles
-
D. Klose, F. Siepmann, K. Elkharraz, S. Krenzlin, and J. Siepmann How porosity and size affect the drug release mechanisms from PLGA-based microparticles Int. J. Pharm. 314 2006 198 206
-
(2006)
Int. J. Pharm.
, vol.314
, pp. 198-206
-
-
Klose, D.1
Siepmann, F.2
Elkharraz, K.3
Krenzlin, S.4
Siepmann, J.5
-
45
-
-
70350046442
-
Photo-cross-linked hydrogels from thermoresponsive PEGMEMA-PPGMA-EGDMA copolymers containing multiple methacrylate groups: Mechanical property, swelling, protein release, cytotoxicity
-
H.H.D. Tai, S. Takae, W. Wang, T. Vermonden, E.W. Hennink, P.S. Stayton, A.S. Hoffman, A. Endruweit, C. Alexander, S.M. Howdle, and K.M. Shakesheff Photo-cross-linked hydrogels from thermoresponsive PEGMEMA-PPGMA-EGDMA copolymers containing multiple methacrylate groups: mechanical property, swelling, protein release, cytotoxicity Biomacromolecules 10 2009 2895 2903
-
(2009)
Biomacromolecules
, vol.10
, pp. 2895-2903
-
-
Tai, H.H.D.1
Takae, S.2
Wang, W.3
Vermonden, T.4
Hennink, E.W.5
Stayton, P.S.6
Hoffman, A.S.7
Endruweit, A.8
Alexander, C.9
Howdle, S.M.10
Shakesheff, K.M.11
-
46
-
-
0035889827
-
Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains: Synthetic ECM analogs for tissue engineering
-
B.K.G.A. Mann, A.T. Tsai, R.H. Schmelen, and J.L. West Smooth muscle cell growth in photopolymerized hydrogels with cell adhesive and proteolytically degradable domains: synthetic ECM analogs for tissue engineering Biomaterials 22 2001
-
(2001)
Biomaterials
, vol.22
-
-
Mann, B.K.G.A.1
Tsai, A.T.2
Schmelen, R.H.3
West, J.L.4
-
47
-
-
0032737267
-
Polymeric biomaterials with degradation sites for proteases involved in cell migration
-
J.L. West, and J.A. Hubbell Polymeric biomaterials with degradation sites for proteases involved in cell migration Macromolecules 32 1999
-
(1999)
Macromolecules
, vol.32
-
-
West, J.L.1
Hubbell, J.A.2
-
48
-
-
37049029660
-
Biomimetic materials for tissue engineering
-
P.X. Ma Biomimetic materials for tissue engineering Adv. Drug. Deliv. Rev. 60 2008 184 198
-
(2008)
Adv. Drug. Deliv. Rev.
, vol.60
, pp. 184-198
-
-
Ma, P.X.1
-
50
-
-
21044440000
-
Enhanced intracellular uptake and inhibition of NF-κβ activation by decoy oligonucleotide released from PLGA microspheres
-
G. De Rosa, M.C. Maiuri, F. Ungaro, D. De Stefano, F. Quaglia, M.I. La Rotonda, and R. Carnuccio Enhanced intracellular uptake and inhibition of NF-κβ activation by decoy oligonucleotide released from PLGA microspheres J. Gene Med. 7 2005
-
(2005)
J. Gene Med.
, vol.7
-
-
De Rosa, G.1
Maiuri, M.C.2
Ungaro, F.3
De Stefano, D.4
Quaglia, F.5
La Rotonda, M.I.6
Carnuccio, R.7
-
51
-
-
33745919229
-
BSA degradation under acidic conditions: A model for protein instability during release from PLGA delivery systems
-
T. Estey, J. Kang, S.P. Schwendeman, and J.F. Carpenter BSA degradation under acidic conditions: a model for protein instability during release from PLGA delivery systems J. Pharm. Sci. 95 2006 1626 1639
-
(2006)
J. Pharm. Sci.
, vol.95
, pp. 1626-1639
-
-
Estey, T.1
Kang, J.2
Schwendeman, S.P.3
Carpenter, J.F.4
-
52
-
-
79961015788
-
In vitro degradation rate of apatitic calcium phosphate cement with incorporated PLGA microspheres
-
R.P. Felix Lanao, S.C. Leeuwenburgh, J.G. Wolke, and J.A. Jansen In vitro degradation rate of apatitic calcium phosphate cement with incorporated PLGA microspheres Acta Biomater. 7 2011 3459 3468
-
(2011)
Acta Biomater.
, vol.7
, pp. 3459-3468
-
-
Felix Lanao, R.P.1
Leeuwenburgh, S.C.2
Wolke, J.G.3
Jansen, J.A.4
-
53
-
-
84893810378
-
A porous tissue engineering scaffold selectively degraded by cell-generated reactive oxygen species
-
J.R. Martin, M.K. Gupta, J.M. Page, F. Yu, J.M. Davidson, S.A. Guelcher, and C.L. Duvall A porous tissue engineering scaffold selectively degraded by cell-generated reactive oxygen species Biomaterials 35 2014 3766 3776
-
(2014)
Biomaterials
, vol.35
, pp. 3766-3776
-
-
Martin, J.R.1
Gupta, M.K.2
Page, J.M.3
Yu, F.4
Davidson, J.M.5
Guelcher, S.A.6
Duvall, C.L.7
-
54
-
-
77958494386
-
Orally delivered thioketal nanoparticles loaded with TNF-α-siRNA target inflammation and inhibit gene expression in the intestines
-
D.S. Wilson, G. Dalmasso, L. Wang, S.V. Sitaraman, D. Merlin, and N. Murthy Orally delivered thioketal nanoparticles loaded with TNF-α-siRNA target inflammation and inhibit gene expression in the intestines Nat. Mater. 9 2010
-
(2010)
Nat. Mater.
, vol.9
-
-
Wilson, D.S.1
Dalmasso, G.2
Wang, L.3
Sitaraman, S.V.4
Merlin, D.5
Murthy, N.6
-
55
-
-
0036000157
-
Surface-tethered DNA complexes for enhanced gene delivery
-
T. Segura, and L.D. Shea Surface-tethered DNA complexes for enhanced gene delivery Bioconjug. Chem. 13 2002
-
(2002)
Bioconjug. Chem.
, vol.13
-
-
Segura, T.1
Shea, L.D.2
-
57
-
-
0038385504
-
RNA interference in mammalian cells by chemically-modified RNA
-
D.A. Braasch, S. Jensen, Y. Liu, K. Kaur, K. Arar, M.A. White, and D.R. Corey RNA interference in mammalian cells by chemically-modified RNA Biochemistry 42 2003
-
(2003)
Biochemistry
, vol.42
-
-
Braasch, D.A.1
Jensen, S.2
Liu, Y.3
Kaur, K.4
Arar, K.5
White, M.A.6
Corey, D.R.7
-
58
-
-
39449097277
-
Overcoming the innate immune response to small interfering RNA
-
A. Judge, and I. MacLachlan Overcoming the innate immune response to small interfering RNA Hum. Gene Ther. 19 2008 111 124
-
(2008)
Hum. Gene Ther.
, vol.19
, pp. 111-124
-
-
Judge, A.1
MacLachlan, I.2
-
59
-
-
0041331496
-
SiRNA function in RNAi: A chemical modification analysis
-
Y.L. Chiu SiRNA function in RNAi: a chemical modification analysis RNA 9 2003 1034 1048
-
(2003)
RNA
, vol.9
, pp. 1034-1048
-
-
Chiu, Y.L.1
-
60
-
-
78649659237
-
Delivery of siRNA therapeutics: Barriers and carriers
-
J. Wang, Z. Lu, M.G. Wientjes, and J.L. Au Delivery of siRNA therapeutics: barriers and carriers AAPS J. 12 2010 492 503
-
(2010)
AAPS J.
, vol.12
, pp. 492-503
-
-
Wang, J.1
Lu, Z.2
Wientjes, M.G.3
Au, J.L.4
-
63
-
-
84856896229
-
Amino-modified and lipid-conjugated dicer-substrate siRNA enhances RNAi efficacy
-
T. Kubo, Y. Takei, K. Mihara, K. Yanagihara, and T. Seyama Amino-modified and lipid-conjugated dicer-substrate siRNA enhances RNAi efficacy Bioconjug. Chem. 23 2012 164 173
-
(2012)
Bioconjug. Chem.
, vol.23
, pp. 164-173
-
-
Kubo, T.1
Takei, Y.2
Mihara, K.3
Yanagihara, K.4
Seyama, T.5
-
64
-
-
41149179660
-
Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol
-
K. Nishina, T. Unno, Y. Uno, T. Kubodera, T. Kanouchi, H. Mizusawa, and T. Yokota Efficient in vivo delivery of siRNA to the liver by conjugation of alpha-tocopherol Mol. Ther. 16 2008 734 740
-
(2008)
Mol. Ther.
, vol.16
, pp. 734-740
-
-
Nishina, K.1
Unno, T.2
Uno, Y.3
Kubodera, T.4
Kanouchi, T.5
Mizusawa, H.6
Yokota, T.7
-
65
-
-
72949119713
-
Lipidic systems for in vivo siRNA delivery
-
S.Y. Wu, and N.A. McMillan Lipidic systems for in vivo siRNA delivery AAPS J. 11 2009 639 652
-
(2009)
AAPS J.
, vol.11
, pp. 639-652
-
-
Wu, S.Y.1
McMillan, N.A.2
-
66
-
-
84926320054
-
Hepatocyte-specific delivery of siRNAs conjugated to novel non-nucleosidic trivalent N-acetylgalactosamine elicits robust gene silencing in vivo
-
K.G. Rajeev, J.K. Nair, M. Jayaraman, K. Charisse, N. Taneja, J. O'Shea, J.L. Willoughby, K. Yucius, T. Nguyen, S. Shulga-Morskaya, S. Milstein, A. Liebow, W. Querbes, A. Borodovsky, K. Fitzgerald, M.A. Maier, and M. Manoharan Hepatocyte-specific delivery of siRNAs conjugated to novel non-nucleosidic trivalent N-acetylgalactosamine elicits robust gene silencing in vivo Chembiochem 16 2015 903 908
-
(2015)
Chembiochem
, vol.16
, pp. 903-908
-
-
Rajeev, K.G.1
Nair, J.K.2
Jayaraman, M.3
Charisse, K.4
Taneja, N.5
O'Shea, J.6
Willoughby, J.L.7
Yucius, K.8
Nguyen, T.9
Shulga-Morskaya, S.10
Milstein, S.11
Liebow, A.12
Querbes, W.13
Borodovsky, A.14
Fitzgerald, K.15
Maier, M.A.16
Manoharan, M.17
-
67
-
-
84929574453
-
SiRNA conjugates carrying sequentially assembled trivalent N-acetylgalactosamine linked through nucleosides elicit robust gene silencing in vivo in hepatocytes
-
S. Matsuda, K. Keiser, J.K. Nair, K. Charisse, R.M. Manoharan, P. Kretschmer, C.G. Peng, A. VKi, P. Kandasamy, J.L. Willoughby, A. Liebow, W. Querbes, K. Yucius, T. Nguyen, S. Milstein, M.A. Maier, K.G. Rajeev, and M. Manoharan SiRNA conjugates carrying sequentially assembled trivalent N-acetylgalactosamine linked through nucleosides elicit robust gene silencing in vivo in hepatocytes ACS Chem. Biol. 10 2015 1181 1187
-
(2015)
ACS Chem. Biol.
, vol.10
, pp. 1181-1187
-
-
Matsuda, S.1
Keiser, K.2
Nair, J.K.3
Charisse, K.4
Manoharan, R.M.5
Kretschmer, P.6
Peng, C.G.7
VKi, A.8
Kandasamy, P.9
Willoughby, J.L.10
Liebow, A.11
Querbes, W.12
Yucius, K.13
Nguyen, T.14
Milstein, S.15
Maier, M.A.16
Rajeev, K.G.17
Manoharan, M.18
-
68
-
-
80051769247
-
Multivalent cyclic RGD conjugates for targeted delivery of small interfering RNA
-
M.R. Alam, X. Ming, M. Fisher, J.G. Lackey, K.G. Rajeev, M. Manoharan, and R.L. Juliano Multivalent cyclic RGD conjugates for targeted delivery of small interfering RNA Bioconjug. Chem. 22 2011 1673 1681
-
(2011)
Bioconjug. Chem.
, vol.22
, pp. 1673-1681
-
-
Alam, M.R.1
Ming, X.2
Fisher, M.3
Lackey, J.G.4
Rajeev, K.G.5
Manoharan, M.6
Juliano, R.L.7
-
69
-
-
34848892144
-
Cell penetrating peptides: Intracellular pathways and pharmaceutical perspectives
-
L.N. Patel, J.L. Zaro, and W.C. Shen Cell penetrating peptides: intracellular pathways and pharmaceutical perspectives Pharm. Res. 24 2007 1977 1992
-
(2007)
Pharm. Res.
, vol.24
, pp. 1977-1992
-
-
Patel, L.N.1
Zaro, J.L.2
Shen, W.C.3
-
70
-
-
25144512412
-
Novel human-derived cell-penetrating peptides for specific subcellular delivery of therapeutic biomolecules
-
C. De Coupade, A. Fittipaldi, V. Chagnas, M. Michel, S. Carlier, E. Tasciotti, A. Darmon, D. Ravel, J. Kearsey, M. Giacca, and F. Cailler Novel human-derived cell-penetrating peptides for specific subcellular delivery of therapeutic biomolecules Biochem. J. 390 2005 407 418
-
(2005)
Biochem. J.
, vol.390
, pp. 407-418
-
-
De Coupade, C.1
Fittipaldi, A.2
Chagnas, V.3
Michel, M.4
Carlier, S.5
Tasciotti, E.6
Darmon, A.7
Ravel, D.8
Kearsey, J.9
Giacca, M.10
Cailler, F.11
-
71
-
-
79954690910
-
Retro-inversion of certain cell-penetrating peptides causes severe cellular toxicity
-
T. Holm, H. Raagel, S.E. Andaloussi, M. Hein, M. Mae, M. Pooga, and U. Langel Retro-inversion of certain cell-penetrating peptides causes severe cellular toxicity Biochim. Biophys. Acta 2011 1808 1544 1551
-
(1808)
Biochim. Biophys. Acta
, vol.2011
, pp. 1544-1551
-
-
Holm, T.1
Raagel, H.2
Andaloussi, S.E.3
Hein, M.4
Mae, M.5
Pooga, M.6
Langel, U.7
-
72
-
-
85065750516
-
Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery
-
H.L.-J.A. Lee, Y. Chen, K.T. Love, A.I. Park, E.D. Karagiannis, A. Sehgal, W. Querbes, C.S. Zurenko, M. Jayaraman, C.G. Peng, K. Charisse, A. Borodovsky, M. Manoharan, J.S. Donahoe, J. Truelove, M. Nahrendorf, R. Langer, and D.G. Anderson Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery Nat. Nanotechnol. 7 2012
-
(2012)
Nat. Nanotechnol.
, vol.7
-
-
Lee, H.L.-J.A.1
Chen, Y.2
Love, K.T.3
Park, A.I.4
Karagiannis, E.D.5
Sehgal, A.6
Querbes, W.7
Zurenko, C.S.8
Jayaraman, M.9
Peng, C.G.10
Charisse, K.11
Borodovsky, A.12
Manoharan, M.13
Donahoe, J.S.14
Truelove, J.15
Nahrendorf, M.16
Langer, R.17
Anderson, D.G.18
-
73
-
-
0037468660
-
Gene silencing by adenovirus-delivered siRNA
-
C. Shen, A.K. Buck, X. Liu, M. Winkler, and S.N. Reske Gene silencing by adenovirus-delivered siRNA FEBS Lett. 539 2003 111 114
-
(2003)
FEBS Lett.
, vol.539
, pp. 111-114
-
-
Shen, C.1
Buck, A.K.2
Liu, X.3
Winkler, M.4
Reske, S.N.5
-
75
-
-
19744372388
-
Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis
-
A. Akinc, M. Thomas, A.M. Klibanov, and R. Langer Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis J. Gene Med. 7 2005 657 663
-
(2005)
J. Gene Med.
, vol.7
, pp. 657-663
-
-
Akinc, A.1
Thomas, M.2
Klibanov, A.M.3
Langer, R.4
-
77
-
-
48949120120
-
Prolonged gene silencing in hepatoma cells and primary hepatocytes after small interfering RNA delivery with biodegradable poly(beta-amino esters)
-
R.E. Vandenbroucke, B.G. De Geest, S. Bonne, M. Vinken, T. Van Haecke, H. Heimberg, E. Wagner, V. Rogiers, S.C. De Smedt, J. Demeester, and N.N. Sanders Prolonged gene silencing in hepatoma cells and primary hepatocytes after small interfering RNA delivery with biodegradable poly(beta-amino esters) J. Gene Med. 10 2008 783 794
-
(2008)
J. Gene Med.
, vol.10
, pp. 783-794
-
-
Vandenbroucke, R.E.1
De Geest, B.G.2
Bonne, S.3
Vinken, M.4
Van Haecke, T.5
Heimberg, H.6
Wagner, E.7
Rogiers, V.8
De Smedt, S.C.9
Demeester, J.10
Sanders, N.N.11
-
78
-
-
0032473410
-
Polylysine-based transfection systems utilizing receptor-mediated delivery
-
W. Zauner, M. Ogris, and E. Wagner Polylysine-based transfection systems utilizing receptor-mediated delivery Adv. Drug Deliv. Rev. 30 1998
-
(1998)
Adv. Drug Deliv. Rev.
, vol.30
-
-
Zauner, W.1
Ogris, M.2
Wagner, E.3
-
79
-
-
78549278716
-
Tocopheryl oligochitosan-based self assembling oligomersomes for siRNA delivery
-
S.M. Noh, S.E. Han, G. Shim, K.E. Lee, C.W. Kim, S.S. Han, Y. Choi, Y.K. Kim, W.K. Kim, and Y.K. Oh Tocopheryl oligochitosan-based self assembling oligomersomes for siRNA delivery Biomaterials 32 2011 849 857
-
(2011)
Biomaterials
, vol.32
, pp. 849-857
-
-
Noh, S.M.1
Han, S.E.2
Shim, G.3
Lee, K.E.4
Kim, C.W.5
Han, S.S.6
Choi, Y.7
Kim, Y.K.8
Kim, W.K.9
Oh, Y.K.10
-
80
-
-
24744464786
-
Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo
-
F. Takeshita, Y. Minakuchi, S. Nagahara, K. Honma, H. Sasaki, K. Hirai, T. Teratani, N. Namatame, Y. Yamamoto, K. Hanai, T. Kato, A. Sano, and T. Ochiya Efficient delivery of small interfering RNA to bone-metastatic tumors by using atelocollagen in vivo Proc. Natl. Acad. Sci. U. S. A. 102 2005 12177 12182
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 12177-12182
-
-
Takeshita, F.1
Minakuchi, Y.2
Nagahara, S.3
Honma, K.4
Sasaki, H.5
Hirai, K.6
Teratani, T.7
Namatame, N.8
Yamamoto, Y.9
Hanai, K.10
Kato, T.11
Sano, A.12
Ochiya, T.13
-
81
-
-
58649092401
-
Development of a novel endosomolytic diblock copolymer for siRNA delivery
-
A.J. Convertine, D.S. Benoit, C.L. Duvall, A.S. Hoffman, and P.S. Stayton Development of a novel endosomolytic diblock copolymer for siRNA delivery J. Control Release 133 2009 221 229
-
(2009)
J. Control Release
, vol.133
, pp. 221-229
-
-
Convertine, A.J.1
Benoit, D.S.2
Duvall, C.L.3
Hoffman, A.S.4
Stayton, P.S.5
-
82
-
-
84879233407
-
Matrix metalloproteinase responsive, proximity-activated polymeric nanoparticles for siRNA delivery
-
H. Li, S.S. Yu, M. Miteva, C.E. Nelson, T. Werfel, T.D. Giorgio, and C.L. Duvall Matrix metalloproteinase responsive, proximity-activated polymeric nanoparticles for siRNA delivery Adv. Funct. Mater. 23 2013 3040 3052
-
(2013)
Adv. Funct. Mater.
, vol.23
, pp. 3040-3052
-
-
Li, H.1
Yu, S.S.2
Miteva, M.3
Nelson, C.E.4
Werfel, T.5
Giorgio, T.D.6
Duvall, C.L.7
-
83
-
-
84887003262
-
Balancing cationic and hydrophobic content of pegylated siRNA polyplexes enhances endosome escape, stability, blood circulation time, and bioactivity in vivo
-
C.E. Nelson, R.J. Kintzing, A. Hanna, J.M. Shannon, M.K. Gupta, and C.L. Duvall Balancing cationic and hydrophobic content of pegylated siRNA polyplexes enhances endosome escape, stability, blood circulation time, and bioactivity in vivo ACS Nano 7 2013 8870 8880
-
(2013)
ACS Nano
, vol.7
, pp. 8870-8880
-
-
Nelson, C.E.1
Kintzing, R.J.2
Hanna, A.3
Shannon, J.M.4
Gupta, M.K.5
Duvall, C.L.6
-
84
-
-
84920876042
-
Dual mmp7-proximity-activated and folate receptor-targeted nanoparticles for siRNA delivery
-
H. Li, M. Miteva, K.C. Kirkbride, M.J. Cheng, C.E. Nelson, E.M. Simpson, M.K. Gupta, C.L. Duvall, and T.D. Giorgio Dual mmp7-proximity-activated and folate receptor-targeted nanoparticles for siRNA delivery Biomacromolecules 16 2015 192 201
-
(2015)
Biomacromolecules
, vol.16
, pp. 192-201
-
-
Li, H.1
Miteva, M.2
Kirkbride, K.C.3
Cheng, M.J.4
Nelson, C.E.5
Simpson, E.M.6
Gupta, M.K.7
Duvall, C.L.8
Giorgio, T.D.9
-
85
-
-
84912080933
-
Tuning pegylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers
-
M. Miteva, K.C. Kirkbride, K.V. Kilchrist, T.A. Werfel, H. Li, C.E. Nelson, M.K. Gupta, T.D. Giorgio, and C.L. Duvall Tuning pegylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers Biomaterials 38 2015 97 107
-
(2015)
Biomaterials
, vol.38
, pp. 97-107
-
-
Miteva, M.1
Kirkbride, K.C.2
Kilchrist, K.V.3
Werfel, T.A.4
Li, H.5
Nelson, C.E.6
Gupta, M.K.7
Giorgio, T.D.8
Duvall, C.L.9
-
87
-
-
84906670921
-
Catch and release: Photocleavable cationic diblock copolymers as a potential platform for nucleic acid delivery
-
M.D. Green, A.A. Foster, C.T. Greco, R. Roy, R.M. Lehr, T.H. Epps III, and M.O. Sullivan Catch and release: photocleavable cationic diblock copolymers as a potential platform for nucleic acid delivery Polym. Chem. 5 2014
-
(2014)
Polym. Chem.
, vol.5
-
-
Green, M.D.1
Foster, A.A.2
Greco, C.T.3
Roy, R.4
Lehr, R.M.5
Epps, T.H.6
Sullivan, M.O.7
-
88
-
-
84899434779
-
Bioreducible cationic polymer-based nanoparticles for efficient and environmentally triggered cytoplasmic siRNA delivery to primary human brain cancer cells
-
K.L. Kozielski, S.Y. Tzeng, B.A. Hurtado De Mendoza, and J.J. Green Bioreducible cationic polymer-based nanoparticles for efficient and environmentally triggered cytoplasmic siRNA delivery to primary human brain cancer cells ACS Nano 8 2015
-
(2015)
ACS Nano
, vol.8
-
-
Kozielski, K.L.1
Tzeng, S.Y.2
Hurtado De Mendoza, B.A.3
Green, J.J.4
-
89
-
-
84889666512
-
Spatially controlled delivery of siRNAs to stem cells in implants generated by multi-component additive manufacturing
-
M.Ø. Andersen, D.Q.S. Le, M. Chen, J.V. Nygaard, M. Kassem, C. Bünger, and J. Kjems Spatially controlled delivery of siRNAs to stem cells in implants generated by multi-component additive manufacturing Adv. Funct. Mater. 23 2013 5599 5607
-
(2013)
Adv. Funct. Mater.
, vol.23
, pp. 5599-5607
-
-
Andersen, M.Ø.1
Le, D.Q.S.2
Chen, M.3
Nygaard, J.V.4
Kassem, M.5
Bünger, C.6
Kjems, J.7
-
90
-
-
77952672525
-
RNA interference by nanofiber-based siRNA delivery system
-
H. Cao, X. Jiang, C. Chai, and S.Y. Chew RNA interference by nanofiber-based siRNA delivery system J. Control Release 144 2010 203 212
-
(2010)
J. Control Release
, vol.144
, pp. 203-212
-
-
Cao, H.1
Jiang, X.2
Chai, C.3
Chew, S.Y.4
-
91
-
-
67749108284
-
Layer-by-layer assembly of all carbon nanotube ultrathin films for electrochemical applications
-
S.W.K.B. Lee, S. Chen, Y. Shao-Horn, and P.T. Hammond Layer-by-layer assembly of all carbon nanotube ultrathin films for electrochemical applications J. Am. Chem. Soc. 131 2008 671 679
-
(2008)
J. Am. Chem. Soc.
, vol.131
, pp. 671-679
-
-
Lee, S.W.K.B.1
Chen, S.2
Shao-Horn, Y.3
Hammond, P.T.4
-
92
-
-
0036011284
-
Controlled release of NFκβ decoy oligonucleotides from biodegradable polymer microparticles
-
X. Zhu, L. Lu, B.L. Currier, A.J. Windebank, and M.J. Yaszemski Controlled release of NFκβ decoy oligonucleotides from biodegradable polymer microparticles Biomaterials 23 2002
-
(2002)
Biomaterials
, vol.23
-
-
Zhu, X.1
Lu, L.2
Currier, B.L.3
Windebank, A.J.4
Yaszemski, M.J.5
-
93
-
-
79959915001
-
Controlled release of anti-inflammatory siRNA from biodegradable polymeric microparticles intended for intra-articular delivery to the temporomandibular joint
-
P.M. Mountziaris, D.C. Sing, S.A. Chew, S.N. Tzouanas, E.D. Lehman, F.K. Kasper, and A.G. Mikos Controlled release of anti-inflammatory siRNA from biodegradable polymeric microparticles intended for intra-articular delivery to the temporomandibular joint Pharm. Res. 28 2011 1370 1384
-
(2011)
Pharm. Res.
, vol.28
, pp. 1370-1384
-
-
Mountziaris, P.M.1
Sing, D.C.2
Chew, S.A.3
Tzouanas, S.N.4
Lehman, E.D.5
Kasper, F.K.6
Mikos, A.G.7
-
94
-
-
0031689425
-
Development of a sustained-release biodegradable polymer delivery system for site-specific delivery of oligonucleotides: Characterization of p(LA-GA) copolymer microspheres in vitro
-
S.J. Lewis, W.J. Irwin, and S. Akhtar Development of a sustained-release biodegradable polymer delivery system for site-specific delivery of oligonucleotides: characterization of p(LA-GA) copolymer microspheres in vitro J. Drug Targets 5 1998
-
(1998)
J. Drug Targets
, vol.5
-
-
Lewis, S.J.1
Irwin, W.J.2
Akhtar, S.3
-
95
-
-
0030919006
-
Antisense oligonucleotide delivery to cultured macrophages is improved by incorporation into sustained-release biodegradablepolymer microspheres
-
S. Akhtar, and K.J. Lewis Antisense oligonucleotide delivery to cultured macrophages is improved by incorporation into sustained-release biodegradablepolymer microspheres Int. J. Pharm. 151 1997
-
(1997)
Int. J. Pharm.
, vol.151
-
-
Akhtar, S.1
Lewis, K.J.2
-
96
-
-
84899489828
-
The effect of combined IL10 siRNA and CPG ODN as pathogen-mimicking microparticles on TH1/TH2 cytokine balance in dendritic cells and protective immunity against B cell lymphoma
-
P. Pradhan, H. Qin, J.A. Leleux, D. Gwak, I. Sakamaki, L.W. Kwak, and K. Roy The effect of combined IL10 siRNA and CPG ODN as pathogen-mimicking microparticles on TH1/TH2 cytokine balance in dendritic cells and protective immunity against B cell lymphoma Biomaterials 35 2014 5491 5504
-
(2014)
Biomaterials
, vol.35
, pp. 5491-5504
-
-
Pradhan, P.1
Qin, H.2
Leleux, J.A.3
Gwak, D.4
Sakamaki, I.5
Kwak, L.W.6
Roy, K.7
-
97
-
-
67849084830
-
In-situ crosslinking hydrogels for combinatorial delivery of chemokines and siRNA-DNA carrying microparticles to dendritic cells
-
A. Singh, S. Suri, and K. Roy In-situ crosslinking hydrogels for combinatorial delivery of chemokines and siRNA-DNA carrying microparticles to dendritic cells Biomaterials 30 2009 5187 5200
-
(2009)
Biomaterials
, vol.30
, pp. 5187-5200
-
-
Singh, A.1
Suri, S.2
Roy, K.3
-
98
-
-
84865514367
-
Intra-articular controlled release of anti-inflammatory siRNA with biodegradable polymer microparticles ameliorates temporomandibular joint inflammation
-
P.M. Mountziaris, S.N. Tzouanas, D.C. Sing, P.R. Kramer, F.K. Kasper, and A.G. Mikos Intra-articular controlled release of anti-inflammatory siRNA with biodegradable polymer microparticles ameliorates temporomandibular joint inflammation Acta Biomater. 8 2012 3552 3560
-
(2012)
Acta Biomater.
, vol.8
, pp. 3552-3560
-
-
Mountziaris, P.M.1
Tzouanas, S.N.2
Sing, D.C.3
Kramer, P.R.4
Kasper, F.K.5
Mikos, A.G.6
-
100
-
-
72449211810
-
Snail1 down-regulation using small interfering RNA complexes delivered through collagen scaffolds
-
R. Vinas-Castells, C. Holladay, A. di Luca, V.M. Diaz, and A. Pandit Snail1 down-regulation using small interfering RNA complexes delivered through collagen scaffolds Bioconjug. Chem. 20 2009
-
(2009)
Bioconjug. Chem.
, vol.20
-
-
Vinas-Castells, R.1
Holladay, C.2
Di Luca, A.3
Diaz, V.M.4
Pandit, A.5
-
101
-
-
77956615316
-
Gene delivery by surface immobilization of plasmid to tissue-engineering scaffolds
-
D.M. Salvay, M. Zelivyanskaya, and L.D. Shea Gene delivery by surface immobilization of plasmid to tissue-engineering scaffolds Gene Ther. 17 2010 1134 1141
-
(2010)
Gene Ther.
, vol.17
, pp. 1134-1141
-
-
Salvay, D.M.1
Zelivyanskaya, M.2
Shea, L.D.3
-
102
-
-
39649102638
-
Biodegradable polyurethanes: Synthesis and applications in regenerative medicine
-
S.A. Guelcher Biodegradable polyurethanes: synthesis and applications in regenerative medicine Tissue Eng. Part B Rev. 14 2008 3 17
-
(2008)
Tissue Eng. Part B Rev.
, vol.14
, pp. 3-17
-
-
Guelcher, S.A.1
-
103
-
-
51649125144
-
Injectable biodegradable polyurethane scaffolds with release of platelet-derived growth factor for tissue repair and regeneration
-
A.E. Hafeman, B. Li, T. Yoshii, K. Zienkiewicz, J.M. Davidson, and S.A. Guelcher Injectable biodegradable polyurethane scaffolds with release of platelet-derived growth factor for tissue repair and regeneration Pharm. Res. 25 2008 2387 2399
-
(2008)
Pharm. Res.
, vol.25
, pp. 2387-2399
-
-
Hafeman, A.E.1
Li, B.2
Yoshii, T.3
Zienkiewicz, K.4
Davidson, J.M.5
Guelcher, S.A.6
-
104
-
-
77954309514
-
Sustained release of vancomycin from polyurethane scaffolds inhibits infection of bone wounds in a rat femoral segmental defect model
-
B. Li, K.V. Brown, J.C. Wenke, and S.A. Guelcher Sustained release of vancomycin from polyurethane scaffolds inhibits infection of bone wounds in a rat femoral segmental defect model J. Control Release 145 2010 221 230
-
(2010)
J. Control Release
, vol.145
, pp. 221-230
-
-
Li, B.1
Brown, K.V.2
Wenke, J.C.3
Guelcher, S.A.4
-
105
-
-
79960922709
-
Hyaluronic acid and fibrin hydrogels with concentrated DNA/pei polyplexes for local gene delivery
-
Y. Lei, M. Rahim, Q. Ng, and T. Segura Hyaluronic acid and fibrin hydrogels with concentrated DNA/pei polyplexes for local gene delivery J. Control Release 153 2011 255 261
-
(2011)
J. Control Release
, vol.153
, pp. 255-261
-
-
Lei, Y.1
Rahim, M.2
Ng, Q.3
Segura, T.4
-
106
-
-
36148971655
-
Delivery of siRNA from lyophilized polymeric surfaces
-
M.O. Andersen, K.A. Howard, S.R. Paludan, F. Besenbacher, and J. Kjems Delivery of siRNA from lyophilized polymeric surfaces Biomaterials 29 2008 506 512
-
(2008)
Biomaterials
, vol.29
, pp. 506-512
-
-
Andersen, M.O.1
Howard, K.A.2
Paludan, S.R.3
Besenbacher, F.4
Kjems, J.5
-
107
-
-
77957312459
-
Incorporation of active DNA/cationic polymer polyplexes into hydrogel scaffolds
-
Y. Lei, S. Huang, P. Sharif-Kashani, Y. Chen, P. Kavehpour, and T. Segura Incorporation of active DNA/cationic polymer polyplexes into hydrogel scaffolds Biomaterials 31 2010 9106 9116
-
(2010)
Biomaterials
, vol.31
, pp. 9106-9116
-
-
Lei, Y.1
Huang, S.2
Sharif-Kashani, P.3
Chen, Y.4
Kavehpour, P.5
Segura, T.6
-
108
-
-
81355161728
-
Sustained local delivery of siRNA from an injectable scaffold
-
C.E. Nelson, M.K. Gupta, E.J. Adolph, J.M. Shannon, S.A. Guelcher, and C.L. Duvall Sustained local delivery of siRNA from an injectable scaffold Biomaterials 33 2012 1154 1161
-
(2012)
Biomaterials
, vol.33
, pp. 1154-1161
-
-
Nelson, C.E.1
Gupta, M.K.2
Adolph, E.J.3
Shannon, J.M.4
Guelcher, S.A.5
Duvall, C.L.6
-
109
-
-
79957907735
-
Nanofiber-mediated controlled release of siRNA complexes for long term gene-silencing applications
-
P.O. Rujitanaroj, Y.C. Wang, J. Wang, and S.Y. Chew Nanofiber-mediated controlled release of siRNA complexes for long term gene-silencing applications Biomaterials 32 2011 5915 5923
-
(2011)
Biomaterials
, vol.32
, pp. 5915-5923
-
-
Rujitanaroj, P.O.1
Wang, Y.C.2
Wang, J.3
Chew, S.Y.4
-
110
-
-
67649948772
-
Localized and sustained delivery of silencing RNA from macroscopic biopolymer hydrogels
-
M.D. Krebs, O. Jeon, and E. Alsberg Localized and sustained delivery of silencing RNA from macroscopic biopolymer hydrogels J. Am. Chem. Soc. 131 2009
-
(2009)
J. Am. Chem. Soc.
, vol.131
-
-
Krebs, M.D.1
Jeon, O.2
Alsberg, E.3
-
111
-
-
84870241193
-
Functionalized, biodegradable hydrogels for control over sustained and localized siRNA delivery to incorporated and surrounding cells
-
K. Nguyen, P.N. Dang, and E. Alsberg Functionalized, biodegradable hydrogels for control over sustained and localized siRNA delivery to incorporated and surrounding cells Acta Biomater. 9 2013 4487 4495
-
(2013)
Acta Biomater.
, vol.9
, pp. 4487-4495
-
-
Nguyen, K.1
Dang, P.N.2
Alsberg, E.3
-
112
-
-
84889666512
-
Spatially controlled delivery of siRNAs to stem cells in implants generated by multi-component additive manufacturing
-
M.Ø. Andersen, D.Q.S. Le, M. Chen, J.V. Nygaard, M. Kassem, C. Bünger, and J. Kjems Spatially controlled delivery of siRNAs to stem cells in implants generated by multi-component additive manufacturing Adv Funct Mater. 23 2013 5599 5607
-
(2013)
Adv Funct Mater.
, vol.23
, pp. 5599-5607
-
-
Andersen, M.Ø.1
Le, D.Q.S.2
Chen, M.3
Nygaard, J.V.4
Kassem, M.5
Bünger, C.6
Kjems, J.7
-
113
-
-
84876173876
-
Synthesis and fabrication of a degradable poly(n-isopropyl acrylamide) scaffold for tissue engineering applications
-
A. Galperin, T.J. Long, S. Garty, and B.D. Ratner Synthesis and fabrication of a degradable poly(n-isopropyl acrylamide) scaffold for tissue engineering applications J. Biomed. Mater. Res. A. 101 2013 775 786
-
(2013)
J. Biomed. Mater. Res. A.
, vol.101
, pp. 775-786
-
-
Galperin, A.1
Long, T.J.2
Garty, S.3
Ratner, B.D.4
-
114
-
-
84908431032
-
Cell protective, ABC triblock polymer-based thermoresponsive hydrogels with ROS-triggered degradation and drug release
-
M.K. Gupta, J.R. Martin, T.A. Werfel, T. Shen, J.M. Page, and C.L. Duvall Cell protective, ABC triblock polymer-based thermoresponsive hydrogels with ROS-triggered degradation and drug release J. Am. Chem. Soc. 136 2014 14896 14902
-
(2014)
J. Am. Chem. Soc.
, vol.136
, pp. 14896-14902
-
-
Gupta, M.K.1
Martin, J.R.2
Werfel, T.A.3
Shen, T.4
Page, J.M.5
Duvall, C.L.6
-
115
-
-
84879887394
-
Dual pH- and temperature-responsive microparticles for protein delivery to ischemic tissues
-
R.V. Joshi, C.E. Nelson, K.M. Poole, M.C. Skala, and C.L. Duvall Dual pH- and temperature-responsive microparticles for protein delivery to ischemic tissues Acta Biomater. 9 2013 6526 6534
-
(2013)
Acta Biomater.
, vol.9
, pp. 6526-6534
-
-
Joshi, R.V.1
Nelson, C.E.2
Poole, K.M.3
Skala, M.C.4
Duvall, C.L.5
-
116
-
-
77955148833
-
Thermally responsive injectable hydrogel incorporating methacrylate-polylactide for hydrolytic lability
-
Z. Ma, D.M. Nelson, Y. Hong, and W.R. Wagner Thermally responsive injectable hydrogel incorporating methacrylate-polylactide for hydrolytic lability Biomacromolecules 11 2010 1873 1881
-
(2010)
Biomacromolecules
, vol.11
, pp. 1873-1881
-
-
Ma, Z.1
Nelson, D.M.2
Hong, Y.3
Wagner, W.R.4
-
117
-
-
84893322819
-
Hydrogel-nanoparticle composites for optically modulated cancer therapeutic delivery
-
L.E. Strong, S.N. Dahotre, and J.L. West Hydrogel-nanoparticle composites for optically modulated cancer therapeutic delivery J. Control Release 178 2014 63 68
-
(2014)
J. Control Release
, vol.178
, pp. 63-68
-
-
Strong, L.E.1
Dahotre, S.N.2
West, J.L.3
-
118
-
-
84938211140
-
A novel injectable thermoresponsive and cytocompatible gel of poly(n-isopropylacrylamide) with layered double hydroxides facilitates siRNA delivery into chondrocytes in 3d culture
-
H.Y. Yang, R.J. van Ee, K. Timmer, E.G. Craenmehr, J.H. Huang, F.C. Oner, W.J. Dhert, A.H. Kragten, N. Willems, G.C. Grinwis, M.A. Tryfonidou, N.E. Papen-Botterhuis, and L.B. Creemers A novel injectable thermoresponsive and cytocompatible gel of poly(n-isopropylacrylamide) with layered double hydroxides facilitates siRNA delivery into chondrocytes in 3d culture Acta Biomater. 2015
-
(2015)
Acta Biomater.
-
-
Yang, H.Y.1
Van Ee, R.J.2
Timmer, K.3
Craenmehr, E.G.4
Huang, J.H.5
Oner, F.C.6
Dhert, W.J.7
Kragten, A.H.8
Willems, N.9
Grinwis, G.C.10
Tryfonidou, M.A.11
Papen-Botterhuis, N.E.12
Creemers, L.B.13
-
119
-
-
84929192704
-
Dual stimuli-responsive redox-active injectable gel by polyion complex based flower micelles for biomedical applications
-
S. Ishii, J. Kaneko, and Y. Nagasaki Dual stimuli-responsive redox-active injectable gel by polyion complex based flower micelles for biomedical applications Macromolecules 48 2015 3088 3094
-
(2015)
Macromolecules
, vol.48
, pp. 3088-3094
-
-
Ishii, S.1
Kaneko, J.2
Nagasaki, Y.3
-
120
-
-
84929992170
-
An in situ gelling liquid crystalline system based on monoglycerides and polyethylenimine for local delivery of siRNAs
-
L.N. Borgheti-Cardoso, L.V. Depieri, S.A. Kooijmans, H. Diniz, R.A. Calzzani, F.T. Vicentini, R. van der Meel, M.C. Fantini, M.M. Iyomasa, R.M. Schiffelers, and M.V. Bentley An in situ gelling liquid crystalline system based on monoglycerides and polyethylenimine for local delivery of siRNAs Eur. J. Pharm. Sci. 74 2015 103 117
-
(2015)
Eur. J. Pharm. Sci.
, vol.74
, pp. 103-117
-
-
Borgheti-Cardoso, L.N.1
Depieri, L.V.2
Kooijmans, S.A.3
Diniz, H.4
Calzzani, R.A.5
Vicentini, F.T.6
Van Der Meel, R.7
Fantini, M.C.8
Iyomasa, M.M.9
Schiffelers, R.M.10
Bentley, M.V.11
-
121
-
-
84875607485
-
An injectable cell penetrable nano-polyplex hydrogel for localized siRNA delivery
-
Y.M. Kim, M.R. Park, and S.C. Song An injectable cell penetrable nano-polyplex hydrogel for localized siRNA delivery Biomaterials 34 2013 4493 4500
-
(2013)
Biomaterials
, vol.34
, pp. 4493-4500
-
-
Kim, Y.M.1
Park, M.R.2
Song, S.C.3
-
122
-
-
84899569836
-
Patterned substrates of nano-graphene oxide mediating highly localized and efficient gene delivery
-
K. Li, L. Feng, J. Shen, Q. Zhang, Z. Liu, S.T. Lee, and J. Liu Patterned substrates of nano-graphene oxide mediating highly localized and efficient gene delivery ACS Appl. Mater. Int. 6 2014 5900 5907
-
(2014)
ACS Appl. Mater. Int.
, vol.6
, pp. 5900-5907
-
-
Li, K.1
Feng, L.2
Shen, J.3
Zhang, Q.4
Liu, Z.5
Lee, S.T.6
Liu, J.7
-
123
-
-
84891736128
-
Tunable staged release of therapeutics from layer-by-layer coatings with clay interlayer barrier
-
J. Min, R.D. Braatz, and P.T. Hammond Tunable staged release of therapeutics from layer-by-layer coatings with clay interlayer barrier Biomaterials 35 2014 2507 2517
-
(2014)
Biomaterials
, vol.35
, pp. 2507-2517
-
-
Min, J.1
Braatz, R.D.2
Hammond, P.T.3
-
124
-
-
74049110958
-
MAD (multiagent delivery) nanolayer: Delivering multiple therapeutics from hierarchically assembled surface coatings
-
B.S. Kim, R.C. Smith, Z. Poon, and P.T. Hammond MAD (multiagent delivery) nanolayer: delivering multiple therapeutics from hierarchically assembled surface coatings Langmuir 25 2009 14086 14092
-
(2009)
Langmuir
, vol.25
, pp. 14086-14092
-
-
Kim, B.S.1
Smith, R.C.2
Poon, Z.3
Hammond, P.T.4
-
125
-
-
84856204235
-
Graphene multilayers as gates for multi-week sequential release of proteins from surfaces
-
J.S.N. Hong, A.C. Drake, P.C. DeMuth, J.B. Lee, J. Chen, and P.T. Hammond Graphene multilayers as gates for multi-week sequential release of proteins from surfaces ACS Nano 6 2012
-
(2012)
ACS Nano
, vol.6
-
-
Hong, J.S.N.1
Drake, A.C.2
DeMuth, P.C.3
Lee, J.B.4
Chen, J.5
Hammond, P.T.6
-
126
-
-
84879643385
-
Nanolayered siRNA dressing for sustained localized knockdown
-
S. Castleberry, M. Wang, and P.T. Hammond Nanolayered siRNA dressing for sustained localized knockdown ACS Nano. 7 2013
-
(2013)
ACS Nano.
, vol.7
-
-
Castleberry, S.1
Wang, M.2
Hammond, P.T.3
-
127
-
-
34548125354
-
Topical matrix-based siRNA silences local gene expression in a murine wound model
-
V.D. Thanik, M.R. Greives, O.Z. Lerman, N. Seiser, W. Dec, C.C. Chang, S.M. Warren, J.P. Levine, and P.B. Saadeh Topical matrix-based siRNA silences local gene expression in a murine wound model Gene Ther. 14 2007
-
(2007)
Gene Ther.
, vol.14
-
-
Thanik, V.D.1
Greives, M.R.2
Lerman, O.Z.3
Seiser, N.4
Dec, W.5
Chang, C.C.6
Warren, S.M.7
Levine, J.P.8
Saadeh, P.B.9
-
128
-
-
79960103014
-
Topical prolyl hydroxylase domain-2 silencing improves diabetic murine wound closure
-
M. Wetterau, F. George, A. Weinstein, P.D. Nguyen, J.P. Tutela, D. Knobel, B.O. Cohen, S.M. Warren, and P.B. Saadeh Topical prolyl hydroxylase domain-2 silencing improves diabetic murine wound closure Wound Repair Regen. 19 2011 481 486
-
(2011)
Wound Repair Regen.
, vol.19
, pp. 481-486
-
-
Wetterau, M.1
George, F.2
Weinstein, A.3
Nguyen, P.D.4
Tutela, J.P.5
Knobel, D.6
Cohen, B.O.7
Warren, S.M.8
Saadeh, P.B.9
-
129
-
-
78349264256
-
Improved diabetic wound healing through topical silencing of p53 is associated with augmented vasculogenic mediators
-
P.D. Nguyen, J.P. Tutela, V.D. Thanik, D. Knobel, R.J. Allen Jr., C.C. Chang, J.P. Levine, S.M. Warren, and P.B. Saadeh Improved diabetic wound healing through topical silencing of p53 is associated with augmented vasculogenic mediators Wound Repair Regen. 18 2010 553 559
-
(2010)
Wound Repair Regen.
, vol.18
, pp. 553-559
-
-
Nguyen, P.D.1
Tutela, J.P.2
Thanik, V.D.3
Knobel, D.4
Allen, R.J.5
Chang, C.C.6
Levine, J.P.7
Warren, S.M.8
Saadeh, P.B.9
-
130
-
-
77955007012
-
Inhibition of SMAD3 expression in radiation-induced fibrosis using a novel method for topical transcutaneous gene therapy
-
J.W. Lee, J.P. Tutela, R.A. Zoumalan, V.D. Thanik, P.D. Nguyen, L. Varjabedian, S.M. Warren, and P.B. Saadeh Inhibition of SMAD3 expression in radiation-induced fibrosis using a novel method for topical transcutaneous gene therapy Arch. Otolaryngol. Head Neck Surg. 136 2010
-
(2010)
Arch. Otolaryngol. Head Neck Surg.
, vol.136
-
-
Lee, J.W.1
Tutela, J.P.2
Zoumalan, R.A.3
Thanik, V.D.4
Nguyen, P.D.5
Varjabedian, L.6
Warren, S.M.7
Saadeh, P.B.8
-
131
-
-
80054692841
-
Vaginal delivery of siRNA using a novel PEGylated lipoplex-entrapped alginate scaffold system
-
S.Y. Wu, H.I. Chang, M. Burgess, and N.A. McMillan Vaginal delivery of siRNA using a novel PEGylated lipoplex-entrapped alginate scaffold system J. Control Release 155 2011 418 426
-
(2011)
J. Control Release
, vol.155
, pp. 418-426
-
-
Wu, S.Y.1
Chang, H.I.2
Burgess, M.3
McMillan, N.A.4
-
132
-
-
84945224337
-
BMP-2, hypoxia, and COL1a1/HTRA1 siRNAs favor neo-cartilage hyaline matrix formation in chondrocytes
-
D. Ollitrault, F. Legendre, C. Drougard, M. Briand, H. Benateau, D. Goux, H. Chajra, L. Poulain, D. Hartmann, D. Vivien, V. Shridhar, A. Baldi, F. Mallein-Gerin, K. Boumediene, M. Demoor, and P. Galera BMP-2, hypoxia, and COL1a1/HTRA1 siRNAs favor neo-cartilage hyaline matrix formation in chondrocytes Tissue Eng. C Meth. 2014
-
(2014)
Tissue Eng. C Meth.
-
-
Ollitrault, D.1
Legendre, F.2
Drougard, C.3
Briand, M.4
Benateau, H.5
Goux, D.6
Chajra, H.7
Poulain, L.8
Hartmann, D.9
Vivien, D.10
Shridhar, V.11
Baldi, A.12
Mallein-Gerin, F.13
Boumediene, K.14
Demoor, M.15
Galera, P.16
-
133
-
-
79955504557
-
Chitosan hydrogel for localized gene silencing
-
H.D. Han, E.M. Mora, J.W. Roh, M. Nishimura, S.J. Lee, R.L. Stone, M. Bar-Eli, G. Lopez-Berestein, and A.K. Sood Chitosan hydrogel for localized gene silencing Cancer Biol. Ther. 11 2011 839 845
-
(2011)
Cancer Biol. Ther.
, vol.11
, pp. 839-845
-
-
Han, H.D.1
Mora, E.M.2
Roh, J.W.3
Nishimura, M.4
Lee, S.J.5
Stone, R.L.6
Bar-Eli, M.7
Lopez-Berestein, G.8
Sood, A.K.9
-
134
-
-
84902693932
-
Chitosan hydrogel as siRNA vector for prolonged gene silencing
-
Z. Ma, C. Yang, W. Song, Q. Wang, J. Kjems, and S. Gao Chitosan hydrogel as siRNA vector for prolonged gene silencing J. Nanobiotechnol. 12 2014
-
(2014)
J. Nanobiotechnol.
, vol.12
-
-
Ma, Z.1
Yang, C.2
Song, W.3
Wang, Q.4
Kjems, J.5
Gao, S.6
-
135
-
-
84877033262
-
Hyaluronic acid/chitosan multilayer coatings on neuronal implants for localized delivery of siRNA nanoplexes
-
H. Hartmann, S. Hossfeld, B. Schlosshauer, U. Mittnacht, A.P. Pego, M. Dauner, M. Doser, D. Stoll, and R. Krastev Hyaluronic acid/chitosan multilayer coatings on neuronal implants for localized delivery of siRNA nanoplexes J. Control Release 168 2013 289 297
-
(2013)
J. Control Release
, vol.168
, pp. 289-297
-
-
Hartmann, H.1
Hossfeld, S.2
Schlosshauer, B.3
Mittnacht, U.4
Pego, A.P.5
Dauner, M.6
Doser, M.7
Stoll, D.8
Krastev, R.9
-
136
-
-
84879883550
-
Bioactive coronary stent coating based on layer-by-layer technology for siRNA release
-
S. Hossfeld, A. Nolte, H. Hartmann, M. Recke, M. Schaller, T. Walker, J. Kjems, B. Schlosshauer, D. Stoll, H.P. Wendel, and R. Krastev Bioactive coronary stent coating based on layer-by-layer technology for siRNA release Acta Biomater. 9 2013 6741 6752
-
(2013)
Acta Biomater.
, vol.9
, pp. 6741-6752
-
-
Hossfeld, S.1
Nolte, A.2
Hartmann, H.3
Recke, M.4
Schaller, M.5
Walker, T.6
Kjems, J.7
Schlosshauer, B.8
Stoll, D.9
Wendel, H.P.10
Krastev, R.11
-
137
-
-
84926181664
-
Acellular dermal matrix-based gene therapy augments graft incorporation
-
M.T. Vandegrift, C. Szpalski, D. Knobel, A. Weinstein, M. Ham, O. Ezeamuzie, S.M. Warren, and P.B. Saadeh Acellular dermal matrix-based gene therapy augments graft incorporation J. Surg. Res. 195 2015 360 367
-
(2015)
J. Surg. Res.
, vol.195
, pp. 360-367
-
-
Vandegrift, M.T.1
Szpalski, C.2
Knobel, D.3
Weinstein, A.4
Ham, M.5
Ezeamuzie, O.6
Warren, S.M.7
Saadeh, P.B.8
-
138
-
-
84921748939
-
Hydrogel doped with nanoparticles for local sustained release of siRNA in breast cancer
-
N. Segovia, M. Pont, N. Oliva, V. Ramos, S. Borros, and N. Artzi Hydrogel doped with nanoparticles for local sustained release of siRNA in breast cancer Adv. Healthc Mater. 4 2015 271 280
-
(2015)
Adv. Healthc Mater.
, vol.4
, pp. 271-280
-
-
Segovia, N.1
Pont, M.2
Oliva, N.3
Ramos, V.4
Borros, S.5
Artzi, N.6
-
139
-
-
80054083256
-
Local delivery of siRNA using a biodegradable polymer application to enhance BMP-induced bone formation
-
T. Manaka, A. Suzuki, K. Takayama, Y. Imai, H. Nakamura, and K. Takaoka Local delivery of siRNA using a biodegradable polymer application to enhance BMP-induced bone formation Biomaterials 32 2011 9642 9648
-
(2011)
Biomaterials
, vol.32
, pp. 9642-9648
-
-
Manaka, T.1
Suzuki, A.2
Takayama, K.3
Imai, Y.4
Nakamura, H.5
Takaoka, K.6
-
140
-
-
84870239023
-
Controlling fibrous capsule formation through long-term down-regulation of collagen type I (COL1a1) expression by nanofiber-mediated siRNA gene silencing
-
P.O. Rujitanaroj, B. Jao, J. Yang, F. Wang, J.M. Anderson, J. Wang, and S.Y. Chew Controlling fibrous capsule formation through long-term down-regulation of collagen type I (COL1a1) expression by nanofiber-mediated siRNA gene silencing Acta Biomater. 9 2013 4513 4524
-
(2013)
Acta Biomater.
, vol.9
, pp. 4513-4524
-
-
Rujitanaroj, P.O.1
Jao, B.2
Yang, J.3
Wang, F.4
Anderson, J.M.5
Wang, J.6
Chew, S.Y.7
-
141
-
-
84875247156
-
Nanofibrous scaffold-mediated REST knockdown to enhance neuronal differentiation of stem cells
-
W.C. Low, P.O. Rujitanaroj, D.K. Lee, P.B. Messersmith, L.W. Stanton, E. Goh, and S.Y. Chew Nanofibrous scaffold-mediated REST knockdown to enhance neuronal differentiation of stem cells Biomaterials 34 2013 3581 3590
-
(2013)
Biomaterials
, vol.34
, pp. 3581-3590
-
-
Low, W.C.1
Rujitanaroj, P.O.2
Lee, D.K.3
Messersmith, P.B.4
Stanton, L.W.5
Goh, E.6
Chew, S.Y.7
-
142
-
-
78049465948
-
SiRNA nanoparticle functionalization of nanostructured scaffolds enables controlled multilineage differentiation of stem cells
-
M.O. Andersen, J.V. Nygaard, J.S. Burns, M.K. Raarup, J.R. Nyengaard, C. Bunger, F. Besenbacher, K.A. Howard, M. Kassem, and J. Kjems SiRNA nanoparticle functionalization of nanostructured scaffolds enables controlled multilineage differentiation of stem cells Mol. Ther. 18 2010 2018 2027
-
(2010)
Mol. Ther.
, vol.18
, pp. 2018-2027
-
-
Andersen, M.O.1
Nygaard, J.V.2
Burns, J.S.3
Raarup, M.K.4
Nyengaard, J.R.5
Bunger, C.6
Besenbacher, F.7
Howard, K.A.8
Kassem, M.9
Kjems, J.10
-
143
-
-
80051815253
-
Directing human embryonic stem cell differentiation by non-viral delivery of siRNA in 3D culture
-
J. Zoldan, A.K. Lytton-Jean, E.D. Karagiannis, K. Deiorio-Haggar, L.M. Bellan, R. Langer, and D.G. Anderson Directing human embryonic stem cell differentiation by non-viral delivery of siRNA in 3D culture Biomaterials 32 2011 7793 7800
-
(2011)
Biomaterials
, vol.32
, pp. 7793-7800
-
-
Zoldan, J.1
Lytton-Jean, A.K.2
Karagiannis, E.D.3
Deiorio-Haggar, K.4
Bellan, L.M.5
Langer, R.6
Anderson, D.G.7
-
144
-
-
67749084133
-
RNA interference for noggin enhances the biological activity of bone morphogenetic proteins in vivo and in vitro
-
K. Takayama, A. Suzuki, T. Manaka, S. Taguchi, Y. Hashimoto, Y. Imai, S. Wakitani, and K. Takaoka RNA interference for noggin enhances the biological activity of bone morphogenetic proteins in vivo and in vitro J. Bone Miner. Metab. 27 2009 402 411
-
(2009)
J. Bone Miner. Metab.
, vol.27
, pp. 402-411
-
-
Takayama, K.1
Suzuki, A.2
Manaka, T.3
Taguchi, S.4
Hashimoto, Y.5
Imai, Y.6
Wakitani, S.7
Takaoka, K.8
-
145
-
-
35748953461
-
Conditional deletion of gremlin causes a transient increase in bone formation and bone mass
-
E. Gazzerro, A. Smerdel-Ramoya, S. Zanotti, L. Stadmeyer, D. Durant, A.N. Economides, and E. Canalis Conditional deletion of gremlin causes a transient increase in bone formation and bone mass J. Biol. Chem. 282 2007 31549 31557
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 31549-31557
-
-
Gazzerro, E.1
Smerdel-Ramoya, A.2
Zanotti, S.3
Stadmeyer, L.4
Durant, D.5
Economides, A.N.6
Canalis, E.7
-
146
-
-
77953809754
-
SiRNA-loaded multi-shell nanoparticles incorporated into a multilayered film as a reservoir for gene silencing
-
X. Zhang, A. Kovtun, C. Mendoza-Palomares, M. Oulad-Abdelghani, F. Fioretti, S. Rinckenbach, D. Mainard, M. Epple, and N. Benkirane-Jessel SiRNA-loaded multi-shell nanoparticles incorporated into a multilayered film as a reservoir for gene silencing Biomaterials 31 2010 6013 6018
-
(2010)
Biomaterials
, vol.31
, pp. 6013-6018
-
-
Zhang, X.1
Kovtun, A.2
Mendoza-Palomares, C.3
Oulad-Abdelghani, M.4
Fioretti, F.5
Rinckenbach, S.6
Mainard, D.7
Epple, M.8
Benkirane-Jessel, N.9
-
147
-
-
47549101861
-
Atelocollagen-mediated local and systemic applications of myostatin-targeting siRNA increase skeletal muscle mass
-
N. Kinouchi, Y. Ohsawa, N. Ishimaru, H. Ohuchi, Y. Sunada, Y. Hayashi, Y. Tanimoto, K. Moriyama, and S. Noji Atelocollagen-mediated local and systemic applications of myostatin-targeting siRNA increase skeletal muscle mass Gene Ther. 15 2008 1126 1130
-
(2008)
Gene Ther.
, vol.15
, pp. 1126-1130
-
-
Kinouchi, N.1
Ohsawa, Y.2
Ishimaru, N.3
Ohuchi, H.4
Sunada, Y.5
Hayashi, Y.6
Tanimoto, Y.7
Moriyama, K.8
Noji, S.9
-
148
-
-
84878063536
-
Local applications of myostatin-siRNA with atelocollagen increase skeletal muscle mass and recovery of muscle function
-
E. Kawakami, N. Kawai, N. Kinouchi, H. Mori, Y. Ohsawa, N. Ishimaru, Y. Sunada, S. Noji, and E. Tanaka Local applications of myostatin-siRNA with atelocollagen increase skeletal muscle mass and recovery of muscle function PloS One 8 2013 e64719
-
(2013)
PloS One
, vol.8
-
-
Kawakami, E.1
Kawai, N.2
Kinouchi, N.3
Mori, H.4
Ohsawa, Y.5
Ishimaru, N.6
Sunada, Y.7
Noji, S.8
Tanaka, E.9
-
149
-
-
79959370889
-
Col v siRNA engineered tenocytes for tendon tissue engineering
-
P. Lu, G.R. Zhang, X.H. Song, X.H. Zou, L.L. Wang, and H.W. Ouyang Col v siRNA engineered tenocytes for tendon tissue engineering PloS One 6 2011
-
(2011)
PloS One
, vol.6
-
-
Lu, P.1
Zhang, G.R.2
Song, X.H.3
Zou, X.H.4
Wang, L.L.5
Ouyang, H.W.6
-
150
-
-
38949205532
-
Suppression of early experimental osteoarthritis by in vivo delivery of the adenoviral vector-mediated nf-kappabp65-specific siRNA
-
L.X. Chen, L. Lin, H.J. Wang, X.L. Wei, X. Fu, J.Y. Zhang, and C.L. Yu Suppression of early experimental osteoarthritis by in vivo delivery of the adenoviral vector-mediated nf-kappabp65-specific siRNA Osteoarthr. Cartilage 16 2008 174 184
-
(2008)
Osteoarthr. Cartilage
, vol.16
, pp. 174-184
-
-
Chen, L.X.1
Lin, L.2
Wang, H.J.3
Wei, X.L.4
Fu, X.5
Zhang, J.Y.6
Yu, C.L.7
-
151
-
-
79959882942
-
Localized delivery of antisense oligonucleotides by cationic hydrogel suppresses TNF-alpha expression and endotoxin-induced osteolysis
-
L. Dong, Z. Huang, X. Cai, J. Xiang, Y.A. Zhu, R. Wang, J. Chen, and J. Zhang Localized delivery of antisense oligonucleotides by cationic hydrogel suppresses TNF-alpha expression and endotoxin-induced osteolysis Pharm. Res. 28 2011 1349 1356
-
(2011)
Pharm. Res.
, vol.28
, pp. 1349-1356
-
-
Dong, L.1
Huang, Z.2
Cai, X.3
Xiang, J.4
Zhu, Y.A.5
Wang, R.6
Chen, J.7
Zhang, J.8
-
152
-
-
84945438370
-
Blockage of Src by specific siRNA as a novel therapeutic strategy to prevent destructive repair in steroid-associated osteonecrosis in rabbits
-
L.C.H. Zheng, S. Chen, T. Tang, W. Fu, L. Huang, D. Ho, K. Chow, Y. Wang, J.F. Griffith, W. He, H. Zhou, D. Zhao, G. Zhang, X. Wang, and L. Qin Blockage of Src by specific siRNA as a novel therapeutic strategy to prevent destructive repair in steroid-associated osteonecrosis in rabbits J. Bone Miner. Res. 2015
-
(2015)
J. Bone Miner. Res.
-
-
Zheng, L.C.H.1
Chen, S.2
Tang, T.3
Fu, W.4
Huang, L.5
Ho, D.6
Chow, K.7
Wang, Y.8
Griffith, J.F.9
He, W.10
Zhou, H.11
Zhao, D.12
Zhang, G.13
Wang, X.14
Qin, L.15
-
153
-
-
84876116755
-
Protective effect of lentivirus-mediated siRNA targeting ADAMTS-5 on cartilage degradation in a rat model of osteoarthritis
-
X. Chu, H. You, X. Yuan, W. Zhao, W. Li, and X. Guo Protective effect of lentivirus-mediated siRNA targeting ADAMTS-5 on cartilage degradation in a rat model of osteoarthritis Int. J. Mol. Med. 31 2013 1222 1228
-
(2013)
Int. J. Mol. Med.
, vol.31
, pp. 1222-1228
-
-
Chu, X.1
You, H.2
Yuan, X.3
Zhao, W.4
Li, W.5
Guo, X.6
-
154
-
-
84930483467
-
Intra-articular delivery of anti-HIF-2alpha siRNA by chondrocyte-homing nanoparticles to prevent cartilage degeneration in arthritic mice
-
Y. Pi, X. Zhang, Z. Shao, F. Zhao, X. Hu, and Y. Ao Intra-articular delivery of anti-HIF-2alpha siRNA by chondrocyte-homing nanoparticles to prevent cartilage degeneration in arthritic mice Gene Ther. 22 2015 439 448
-
(2015)
Gene Ther.
, vol.22
, pp. 439-448
-
-
Pi, Y.1
Zhang, X.2
Shao, Z.3
Zhao, F.4
Hu, X.5
Ao, Y.6
-
155
-
-
34248225758
-
Cellular and molecular basis of wound healing in diabetes
-
H. Brem, and M. Tomic-Canic Cellular and molecular basis of wound healing in diabetes J. Clin. Invest. 117 2007 1219 1222
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1219-1222
-
-
Brem, H.1
Tomic-Canic, M.2
-
156
-
-
84886750021
-
Non-viral DNA delivery from porous hyaluronic acid hydrogels in mice
-
T. Tokatlian, C. Cam, and T. Segura Non-viral DNA delivery from porous hyaluronic acid hydrogels in mice Biomaterials 35 2014 825 835
-
(2014)
Biomaterials
, vol.35
, pp. 825-835
-
-
Tokatlian, T.1
Cam, C.2
Segura, T.3
-
157
-
-
23844480941
-
Plasmid delivery in vivo from porous tissue-engineering scaffolds: Transgene expression and cellular transfection
-
J.H. Jang, C.B. Rives, and L.D. Shea Plasmid delivery in vivo from porous tissue-engineering scaffolds: transgene expression and cellular transfection Mol. Ther. 12 2005 475 483
-
(2005)
Mol. Ther.
, vol.12
, pp. 475-483
-
-
Jang, J.H.1
Rives, C.B.2
Shea, L.D.3
-
158
-
-
68949099629
-
VEGF therapy: A timely retreat
-
A. Alfranca VEGF therapy: a timely retreat Cardiovasc. Res. 83 2009 611 612
-
(2009)
Cardiovasc. Res.
, vol.83
, pp. 611-612
-
-
Alfranca, A.1
-
159
-
-
84883780219
-
Enhancing microvascular formation and vessel maturation through temporal control over multiple pro-angiogenic and pro-maturation factors
-
Y. Brudno, A.B. Ennett-Shepard, R.R. Chen, M. Aizenberg, and D.J. Mooney Enhancing microvascular formation and vessel maturation through temporal control over multiple pro-angiogenic and pro-maturation factors Biomaterials 34 2013 9201 9209
-
(2013)
Biomaterials
, vol.34
, pp. 9201-9209
-
-
Brudno, Y.1
Ennett-Shepard, A.B.2
Chen, R.R.3
Aizenberg, M.4
Mooney, D.J.5
-
160
-
-
34249306597
-
Regulation and guidance of cell behavior for tissue regeneration via the siRNA mechanism
-
S.K. Cheema, E. Chen, L.D. Shea, and A.B. Mathur Regulation and guidance of cell behavior for tissue regeneration via the siRNA mechanism Wound Repair Regen. 15 2007 286 295
-
(2007)
Wound Repair Regen.
, vol.15
, pp. 286-295
-
-
Cheema, S.K.1
Chen, E.2
Shea, L.D.3
Mathur, A.B.4
-
161
-
-
85047682984
-
Regulation of oxygen homeostasis by hypoxia-inducible factor 1
-
G.L. Semenza Regulation of oxygen homeostasis by hypoxia-inducible factor 1 Physiology 24 2009 97 106
-
(2009)
Physiology
, vol.24
, pp. 97-106
-
-
Semenza, G.L.1
-
162
-
-
84857458226
-
Prolyl hydroxylase inhibitors increase the production of vascular endothelial growth factor by periodontal fibroblasts
-
H. Agis, G. Watzek, and R. Gruber Prolyl hydroxylase inhibitors increase the production of vascular endothelial growth factor by periodontal fibroblasts J. Periodontal Res. 47 2012 165 173
-
(2012)
J. Periodontal Res.
, vol.47
, pp. 165-173
-
-
Agis, H.1
Watzek, G.2
Gruber, R.3
-
163
-
-
59649117924
-
Heterozygous deficiency of phd2 restores tumor oxygenation and inhibits metastasis via endothelial normalization
-
M. Mazzone, D. Dettori, R. Leite de Oliveira, S. Loges, T. Schmidt, B. Jonckx, Y.M. Tian, A.A. Lanahan, P. Pollard, C. Ruiz de Almodovar, F. De Smet, S. Vinckier, J. Aragones, K. Debackere, A. Luttun, S. Wyns, B. Jordan, A. Pisacane, B. Gallez, M.G. Lampugnani, E. Dejana, M. Simons, P. Ratcliffe, P. Maxwell, and P. Carmeliet Heterozygous deficiency of phd2 restores tumor oxygenation and inhibits metastasis via endothelial normalization Cell 136 2009 839 851
-
(2009)
Cell
, vol.136
, pp. 839-851
-
-
Mazzone, M.1
Dettori, D.2
Leite De Oliveira, R.3
Loges, S.4
Schmidt, T.5
Jonckx, B.6
Tian, Y.M.7
Lanahan, A.A.8
Pollard, P.9
Ruiz De Almodovar, C.10
De Smet, F.11
Vinckier, S.12
Aragones, J.13
Debackere, K.14
Luttun, A.15
Wyns, S.16
Jordan, B.17
Pisacane, A.18
Gallez, B.19
Lampugnani, M.G.20
Dejana, E.21
Simons, M.22
Ratcliffe, P.23
Maxwell, P.24
Carmeliet, P.25
more..
-
164
-
-
35348843493
-
Inhibition of smad3 expression decreases collagen synthesis in keloid disease fibroblasts
-
Z. Wang, Z. Gao, Y. Shi, Y. Sun, Z. Lin, H. Jiang, T. Hou, Q. Wang, X. Yuan, X. Zhu, H. Wu, and Y. Jin Inhibition of smad3 expression decreases collagen synthesis in keloid disease fibroblasts J. Plast. Reconstr. Aesthet. 60 2007 1193 1199
-
(2007)
J. Plast. Reconstr. Aesthet.
, vol.60
, pp. 1193-1199
-
-
Wang, Z.1
Gao, Z.2
Shi, Y.3
Sun, Y.4
Lin, Z.5
Jiang, H.6
Hou, T.7
Wang, Q.8
Yuan, X.9
Zhu, X.10
Wu, H.11
Jin, Y.12
-
165
-
-
0036675752
-
Synthetic TGF-β antagonist accelerates wound healing and reduces scarring
-
J.S. Huang, Y. Wang, T. Ling, S. Chuang, F.E. Johnson, and S.S. Huang Synthetic TGF-β antagonist accelerates wound healing and reduces scarring FASEB J. 16 2002
-
(2002)
FASEB J.
, vol.16
-
-
Huang, J.S.1
Wang, Y.2
Ling, T.3
Chuang, S.4
Johnson, F.E.5
Huang, S.S.6
-
166
-
-
14544297836
-
RNA interference targeting transforming growth factor-β type II receptor suppresses ocular inflammation and fibrosis
-
H. Nakamura, S.S. Siddiqui, X. Shen, A.B. Malik, J.S. Pulido, N.M. Kumar, and B.Y. Yue RNA interference targeting transforming growth factor-β type II receptor suppresses ocular inflammation and fibrosis Mol. Vis. 10 2004
-
(2004)
Mol. Vis.
, vol.10
-
-
Nakamura, H.1
Siddiqui, S.S.2
Shen, X.3
Malik, A.B.4
Pulido, J.S.5
Kumar, N.M.6
Yue, B.Y.7
-
167
-
-
84894472709
-
Triple combination of siRNAs targeting TGFbeta1, TGFbetaR2, and CTGF enhances reduction of collagen I and smooth muscle actin in corneal fibroblasts
-
S. Sriram, P. Robinson, L. Pi, A.S. Lewin, and G. Schultz Triple combination of siRNAs targeting TGFbeta1, TGFbetaR2, and CTGF enhances reduction of collagen I and smooth muscle actin in corneal fibroblasts Invest. Ophthalmol. Vis. Sci. 54 2013 8214 8223
-
(2013)
Invest. Ophthalmol. Vis. Sci.
, vol.54
, pp. 8214-8223
-
-
Sriram, S.1
Robinson, P.2
Pi, L.3
Lewin, A.S.4
Schultz, G.5
-
168
-
-
84894074911
-
Erk2 small interfering RNAs prevent epidural fibrosis via the efficient inhibition of collagen expression and inflammation in laminectomy rats
-
C. Zhang, X. Kong, C. Liu, Z. Liang, H. Zhao, W. Tong, G. Ning, W. Shen, L. Yao, and S. Feng Erk2 small interfering RNAs prevent epidural fibrosis via the efficient inhibition of collagen expression and inflammation in laminectomy rats Biochem. Biophys. Res. Commun. 444 2014 395 400
-
(2014)
Biochem. Biophys. Res. Commun.
, vol.444
, pp. 395-400
-
-
Zhang, C.1
Kong, X.2
Liu, C.3
Liang, Z.4
Zhao, H.5
Tong, W.6
Ning, G.7
Shen, W.8
Yao, L.9
Feng, S.10
-
169
-
-
78049478521
-
Device-based local delivery of siRNA against mammalian target of rapamycin (mTOR) in a murine subcutaneous implant model to inhibit fibrous encapsulation
-
H. Takahashi, Y. Wang, and D.W. Grainger Device-based local delivery of siRNA against mammalian target of rapamycin (mTOR) in a murine subcutaneous implant model to inhibit fibrous encapsulation J. Control Release 147 2010 400 407
-
(2010)
J. Control Release
, vol.147
, pp. 400-407
-
-
Takahashi, H.1
Wang, Y.2
Grainger, D.W.3
-
170
-
-
70349873365
-
Amelioration of psoriasis by anti-TNF-alpha RNAi in the xenograft transplantation model
-
M. Jakobsen, K. Stenderup, C. Rosada, B. Moldt, S. Kamp, T.N. Dam, T.G. Jensen, and J.G. Mikkelsen Amelioration of psoriasis by anti-TNF-alpha RNAi in the xenograft transplantation model Mol. Ther. 17 2009 1743 1753
-
(2009)
Mol. Ther.
, vol.17
, pp. 1743-1753
-
-
Jakobsen, M.1
Stenderup, K.2
Rosada, C.3
Moldt, B.4
Kamp, S.5
Dam, T.N.6
Jensen, T.G.7
Mikkelsen, J.G.8
-
171
-
-
33746913567
-
Engineering mucosal RNA interference in vivo
-
Y. Zhang, P. Cristofaro, R. Silbermann, O. Pusch, D. Boden, T. Konkin, V. Hovanesian, P.R. Monfils, M. Resnick, S.F. Moss, and B. Ramratnam Engineering mucosal RNA interference in vivo Mol. Ther. 14 2006 336 342
-
(2006)
Mol. Ther.
, vol.14
, pp. 336-342
-
-
Zhang, Y.1
Cristofaro, P.2
Silbermann, R.3
Pusch, O.4
Boden, D.5
Konkin, T.6
Hovanesian, V.7
Monfils, P.R.8
Resnick, M.9
Moss, S.F.10
Ramratnam, B.11
-
172
-
-
70350142394
-
An immobilized nanoparticle-based platform for efficient gene knockdown of targeted cells in the circulation
-
Z. Huang, and M.R. King An immobilized nanoparticle-based platform for efficient gene knockdown of targeted cells in the circulation Gene Ther. 16 2009 1271 1282
-
(2009)
Gene Ther.
, vol.16
, pp. 1271-1282
-
-
Huang, Z.1
King, M.R.2
-
173
-
-
9644291513
-
Long-term patency of saphenous vein and left internal mammary artery grafts after coronary artery bypass surgery: Results from a department of veterans affairs cooperative study
-
S. Goldman, K. Zadina, T. Moritz, T. Ovitt, G. Sethi, J.G. Copeland, L. Thottapurathu, B. Krasnicka, N. Ellis, R.J. Anderson, W. Henderson, and V.A.C.S. Group Long-term patency of saphenous vein and left internal mammary artery grafts after coronary artery bypass surgery: results from a department of veterans affairs cooperative study J. Am. Coll. Cardiol. 44 2004 2149 2156
-
(2004)
J. Am. Coll. Cardiol.
, vol.44
, pp. 2149-2156
-
-
Goldman, S.1
Zadina, K.2
Moritz, T.3
Ovitt, T.4
Sethi, G.5
Copeland, J.G.6
Thottapurathu, L.7
Krasnicka, B.8
Ellis, N.9
Anderson, R.J.10
Henderson, W.11
-
174
-
-
70449472493
-
Development of a functionalized polymer for stent coating in the arterial delivery of small interfering RNA
-
A. San Juan, M. Bala, H. Hlawaty, P. Portes, R. Vranckx, L.J. Feldman, and D. Letourneur Development of a functionalized polymer for stent coating in the arterial delivery of small interfering RNA Biomacromolecules 10 2009
-
(2009)
Biomacromolecules
, vol.10
-
-
San Juan, A.1
Bala, M.2
Hlawaty, H.3
Portes, P.4
Vranckx, R.5
Feldman, L.J.6
Letourneur, D.7
-
175
-
-
84930812527
-
MK2 inhibitory peptide delivered in nanopolyplexes prevents vascular graft intimal hyperplasia
-
B.C. Evans, K.M. Hocking, M.J. Osgood, I. Voskresensky, J. Dmowska, K.V. Kilchrist, C.M. Brophy, and C.L. Duvall MK2 inhibitory peptide delivered in nanopolyplexes prevents vascular graft intimal hyperplasia Sci. Transl. Med. 7 2015
-
(2015)
Sci. Transl. Med.
, vol.7
-
-
Evans, B.C.1
Hocking, K.M.2
Osgood, M.J.3
Voskresensky, I.4
Dmowska, J.5
Kilchrist, K.V.6
Brophy, C.M.7
Duvall, C.L.8
-
176
-
-
0036851826
-
Vascular proliferation and atherosclerosis: New perspectives and therapeutic strategies
-
V.J.R.C. Dzau, and D.G. Sedding Vascular proliferation and atherosclerosis: new perspectives and therapeutic strategies Nat. Med. 8 2002
-
(2002)
Nat. Med.
, vol.8
-
-
Dzau, V.J.R.C.1
Sedding, D.G.2
-
177
-
-
84895016937
-
Gene silencing in human aortic smooth muscle cells induced by pei-siRNA complexes released from dip-coated electrospun poly(ethylene terephthalate) grafts
-
C.S. Nabzdyk, M.C. Chun, H.S. Oliver-Allen, S.G. Pathan, M.D. Phaneuf, J.O. You, L.K. Pradhan-Nabzdyk, and F.W. LoGerfo Gene silencing in human aortic smooth muscle cells induced by pei-siRNA complexes released from dip-coated electrospun poly(ethylene terephthalate) grafts Biomaterials 35 2014 3071 3079
-
(2014)
Biomaterials
, vol.35
, pp. 3071-3079
-
-
Nabzdyk, C.S.1
Chun, M.C.2
Oliver-Allen, H.S.3
Pathan, S.G.4
Phaneuf, M.D.5
You, J.O.6
Pradhan-Nabzdyk, L.K.7
LoGerfo, F.W.8
-
178
-
-
30144434185
-
An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection
-
D. Palliser, D. Chowdhury, Q.Y. Wang, S.J. Lee, R.T. Bronson, D.M. Knipe, and J. Lieberman An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection Nature 439 2006 89 94
-
(2006)
Nature
, vol.439
, pp. 89-94
-
-
Palliser, D.1
Chowdhury, D.2
Wang, Q.Y.3
Lee, S.J.4
Bronson, R.T.5
Knipe, D.M.6
Lieberman, J.7
-
179
-
-
66249083866
-
Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA
-
K.A. Woodrow, Y. Cu, C.J. Booth, J.K. Saucier-Sawyer, M.J. Wood, and W.M. Saltzman Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA Nat. Mater. 8 2009
-
(2009)
Nat. Mater.
, vol.8
-
-
Woodrow, K.A.1
Cu, Y.2
Booth, C.J.3
Saucier-Sawyer, J.K.4
Wood, M.J.5
Saltzman, W.M.6
-
180
-
-
84864262905
-
Injectable polyplex hydrogel for localized and long-term delivery of siRNA
-
Y. Kim, M. Park, and S. Song Injectable polyplex hydrogel for localized and long-term delivery of siRNA ACS Nano 6 2012
-
(2012)
ACS Nano
, vol.6
-
-
Kim, Y.1
Park, M.2
Song, S.3
-
181
-
-
84890824325
-
Mutant KRAS is a druggable target for pancreatic cancer
-
E.Z. Khvalevsky, R. Gabai, I.H. Rachmut, E. Horwitz, Z. Brunschwig, A. Orbach, A. Shemi, T. Golan, A.J. Domb, E. Yavin, H. Giladi, L. Rivkin, A. Simerzin, R. Eliakim, A. Khalaileh, A. Hubert, M. Lahav, Y. Kopelman, E. Goldin, A. Dancour, Y. Hants, S. Arbel-Alon, R. Abramovitch, A. Shemi, and E. Galun Mutant KRAS is a druggable target for pancreatic cancer Proc. Natl. Acad. Sci. U. S. A. 110 2013 20723 20728
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. 20723-20728
-
-
Khvalevsky, E.Z.1
Gabai, R.2
Rachmut, I.H.3
Horwitz, E.4
Brunschwig, Z.5
Orbach, A.6
Shemi, A.7
Golan, T.8
Domb, A.J.9
Yavin, E.10
Giladi, H.11
Rivkin, L.12
Simerzin, A.13
Eliakim, R.14
Khalaileh, A.15
Hubert, A.16
Lahav, M.17
Kopelman, Y.18
Goldin, E.19
Dancour, A.20
Hants, Y.21
Arbel-Alon, S.22
Abramovitch, R.23
Shemi, A.24
Galun, E.25
more..
-
183
-
-
40449092256
-
Controlled delivery of T-box21 small interfering RNA ameliorates autoimmune alopecia (alopecia areata) in a C3H/HEJ mouse model
-
M. Nakamura, J. Jo, Y. Tabata, and O. Ishikawa Controlled delivery of T-box21 small interfering RNA ameliorates autoimmune alopecia (alopecia areata) in a C3H/HEJ mouse model Am. J. Pathol. 172 2008 650 658
-
(2008)
Am. J. Pathol.
, vol.172
, pp. 650-658
-
-
Nakamura, M.1
Jo, J.2
Tabata, Y.3
Ishikawa, O.4
-
184
-
-
45749085675
-
Topical application of cream-emulsified CD86 siRNA ameliorates allergic skin disease by targeting cutaneous dendritic cells
-
P. Ritprajak, M. Hashiguchi, and M. Azuma Topical application of cream-emulsified CD86 siRNA ameliorates allergic skin disease by targeting cutaneous dendritic cells Mol. Ther. 16 2008 1323 1330
-
(2008)
Mol. Ther.
, vol.16
, pp. 1323-1330
-
-
Ritprajak, P.1
Hashiguchi, M.2
Azuma, M.3
-
185
-
-
69949136638
-
Connective tissue growth factor: Growth factor, matricellular organizer, fibrotic biomarker or molecular target for anti-fibrotic therapy in SSC?
-
D. Abraham Connective tissue growth factor: growth factor, matricellular organizer, fibrotic biomarker or molecular target for anti-fibrotic therapy in SSC? Rheumatology 47 Suppl. 5 2008 v8 v9
-
(2008)
Rheumatology
, vol.47
, pp. v8-v9
-
-
Abraham, D.1
-
186
-
-
77950462015
-
Lack of p21 expression links cell cycle control and appendage regeneration in mice
-
K. Bedelbaeva, A. Snyder, D. Gourevitch, L. Clark, X.M. Zhang, J. Leferovich, J.M. Cheverud, P. Lieberman, and E. Heber-Katz Lack of p21 expression links cell cycle control and appendage regeneration in mice Proc. Natl. Acad. Sci. U. S. A. 107 2010 5845 5850
-
(2010)
Proc. Natl. Acad. Sci. U. S. A.
, vol.107
, pp. 5845-5850
-
-
Bedelbaeva, K.1
Snyder, A.2
Gourevitch, D.3
Clark, L.4
Zhang, X.M.5
Leferovich, J.6
Cheverud, J.M.7
Lieberman, P.8
Heber-Katz, E.9
-
187
-
-
84903816671
-
Angiogenic/osteogenic response of bmmscs on bone-derived scaffold: Effect of hypoxia and role of PI3K/AKT-mediated VEGF-VEGFR pathway
-
Y. Zhou, X. Guan, M. Yu, X. Wang, W. Zhu, C. Wang, M. Yu, and H. Wang Angiogenic/osteogenic response of bmmscs on bone-derived scaffold: effect of hypoxia and role of PI3K/AKT-mediated VEGF-VEGFR pathway Biotechnol. J. 9 2014 944 953
-
(2014)
Biotechnol. J.
, vol.9
, pp. 944-953
-
-
Zhou, Y.1
Guan, X.2
Yu, M.3
Wang, X.4
Zhu, W.5
Wang, C.6
Yu, M.7
Wang, H.8
-
188
-
-
84903449853
-
Targetable micelleplex hydrogel for long-term, effective, and systemic siRNA delivery
-
Y.M. Kim, and S.C. Song Targetable micelleplex hydrogel for long-term, effective, and systemic siRNA delivery Biomaterials. 35 2014 7970 7977
-
(2014)
Biomaterials.
, vol.35
, pp. 7970-7977
-
-
Kim, Y.M.1
Song, S.C.2
-
189
-
-
84906334255
-
Cancer-specific gene silencing through therapeutic siRNA delivery with B vitamin-based nanoassembled low-molecular-weight hydrogelators
-
S.P. Patil, S.H. Kim, J.R. Jadhav, J.H. Lee, E.M. Jeon, K.T. Kim, and B.H. Kim Cancer-specific gene silencing through therapeutic siRNA delivery with B vitamin-based nanoassembled low-molecular-weight hydrogelators Bioconjug. Chem. 2014
-
(2014)
Bioconjug. Chem.
-
-
Patil, S.P.1
Kim, S.H.2
Jadhav, J.R.3
Lee, J.H.4
Jeon, E.M.5
Kim, K.T.6
Kim, B.H.7
-
190
-
-
78751667739
-
An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4 + t cell decline in humanized mice
-
C.P. Neff, J. Zhou, L. Remling, J. Kuruvilla, J. Zhang, H. Li, D.D. Smith, P. Swiderski, J.J. Rossi, and R. Akkina An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4 + t cell decline in humanized mice Sci. Transl. Med. 3 2011
-
(2011)
Sci. Transl. Med.
, vol.3
-
-
Neff, C.P.1
Zhou, J.2
Remling, L.3
Kuruvilla, J.4
Zhang, J.5
Li, H.6
Smith, D.D.7
Swiderski, P.8
Rossi, J.J.9
Akkina, R.10
-
191
-
-
84902553548
-
Tumor targeting RGD conjugated bio-reducible polymer for VEGF siRNA expressing plasmid delivery
-
H.A. Kim, K. Nam, and S.W. Kim Tumor targeting RGD conjugated bio-reducible polymer for VEGF siRNA expressing plasmid delivery Biomaterials 35 2014 7543 7552
-
(2014)
Biomaterials
, vol.35
, pp. 7543-7552
-
-
Kim, H.A.1
Nam, K.2
Kim, S.W.3
-
192
-
-
79951849229
-
RNA interference therapy in lung transplant patients infected with respiratory syncytial virus
-
M.R. Zamora, M. Budev, M. Rolfe, J. Gottlieb, A. Humar, J. Devincenzo, A. Vaishnaw, J. Cehelsky, G. Albert, S. Nochur, J.A. Gollob, and A.R. Glanville RNA interference therapy in lung transplant patients infected with respiratory syncytial virus Am. J. Respir. Crit. Care 183 2011 531 538
-
(2011)
Am. J. Respir. Crit. Care
, vol.183
, pp. 531-538
-
-
Zamora, M.R.1
Budev, M.2
Rolfe, M.3
Gottlieb, J.4
Humar, A.5
Devincenzo, J.6
Vaishnaw, A.7
Cehelsky, J.8
Albert, G.9
Nochur, S.10
Gollob, J.A.11
Glanville, A.R.12
-
193
-
-
77953909544
-
SiRNA-027 study I. RNAi-based treatment for neovascular age-related macular degeneration by siRNA-027
-
e32
-
P.K. Kaiser, R.C. Symons, S.M. Shah, E.J. Quinlan, H. Tabandeh, D.V. Do, G. Reisen, J.A. Lockridge, B. Short, R. Guerciolini, and Q.D. Nguyen SiRNA-027 study I. RNAi-based treatment for neovascular age-related macular degeneration by siRNA-027 Am. J. Opthalmol. 150 2010 33 39 e32
-
(2010)
Am. J. Opthalmol.
, vol.150
, pp. 33-39
-
-
Kaiser, P.K.1
Symons, R.C.2
Shah, S.M.3
Quinlan, E.J.4
Tabandeh, H.5
Do, D.V.6
Reisen, G.7
Lockridge, J.A.8
Short, B.9
Guerciolini, R.10
Nguyen, Q.D.11
-
194
-
-
76349084709
-
First-in-human mutation-targeted siRNA phase ib trial of an inherited skin disorder
-
S.A. Leachman, R.P. Hickerson, M.E. Schwartz, E.E. Bullough, S.L. Hutcherson, K.M. Boucher, C.D. Hansen, M.J. Eliason, G.S. Srivatsa, D.J. Kornbrust, F.J. Smith, W.I. McLean, L.M. Milstone, and R.L. Kaspar First-in-human mutation-targeted siRNA phase ib trial of an inherited skin disorder Mol. Ther. 18 2010 442 446
-
(2010)
Mol. Ther.
, vol.18
, pp. 442-446
-
-
Leachman, S.A.1
Hickerson, R.P.2
Schwartz, M.E.3
Bullough, E.E.4
Hutcherson, S.L.5
Boucher, K.M.6
Hansen, C.D.7
Eliason, M.J.8
Srivatsa, G.S.9
Kornbrust, D.J.10
Smith, F.J.11
McLean, W.I.12
Milstone, L.M.13
Kaspar, R.L.14
-
195
-
-
84877130036
-
Clinical development of synthetic siRNA therapeutics
-
J.D. Thompson Clinical development of synthetic siRNA therapeutics Drug Discov. Today 10 2013 e133 e138
-
(2013)
Drug Discov. Today
, vol.10
, pp. e133-e138
-
-
Thompson, J.D.1
-
197
-
-
84862317270
-
RNA interference trigger variants: Getting the most out of RNA for RNA interference-based therapeutics
-
N.M. Snead, and J.J. Rossi RNA interference trigger variants: getting the most out of RNA for RNA interference-based therapeutics Nucleic Acid Ther. 22 2012 139 146
-
(2012)
Nucleic Acid Ther.
, vol.22
, pp. 139-146
-
-
Snead, N.M.1
Rossi, J.J.2
-
198
-
-
1242297011
-
Intravitreal injection of vascular endothelial growth factor small interfering RNA inhibits growth and leakage in a nonhuman primate, laser-induced model of choroidal neovascularization
-
M.J. Tolentino, A.J. Brucker, J. Fosnot, G.S. Ying, I.H. Wu, G. Malik, S. Wan, and S.J. Reich Intravitreal injection of vascular endothelial growth factor small interfering RNA inhibits growth and leakage in a nonhuman primate, laser-induced model of choroidal neovascularization Retina-J. Ret. Vit. Dis. 24 2004
-
(2004)
Retina-J. Ret. Vit. Dis.
, vol.24
-
-
Tolentino, M.J.1
Brucker, A.J.2
Fosnot, J.3
Ying, G.S.4
Wu, I.H.5
Malik, G.6
Wan, S.7
Reich, S.J.8
-
199
-
-
44949220320
-
Ocular biodistribution of bevasiranib following a single intravitreal injection to rabbit eyes
-
N.S. Dejneka, S. Wan, O.S. Bond, D.J. Kornbrust, and S.J. Reich Ocular biodistribution of bevasiranib following a single intravitreal injection to rabbit eyes Mol Vis. 14 2008
-
(2008)
Mol Vis.
, vol.14
-
-
Dejneka, N.S.1
Wan, S.2
Bond, O.S.3
Kornbrust, D.J.4
Reich, S.J.5
-
207
-
-
84864855385
-
Phase 1 dose-escalation study of a siRNA targeting the RTP801 gene in age-related macular degeneration patients
-
Q.D. Nguyen, R.A. Schachar, C.I. Nduaka, M. Sperling, A.S. Basile, K.J. Klamerus, K. Chi-Burris, E. Yan, D.A. Paggiarino, I. Rosenblatt, A. Khan, R. Aitchison, S.S. Erlich, and P.F.S. Group Phase 1 dose-escalation study of a siRNA targeting the RTP801 gene in age-related macular degeneration patients Eye. 26 2012 1099 1105
-
(2012)
Eye.
, vol.26
, pp. 1099-1105
-
-
Nguyen, Q.D.1
Schachar, R.A.2
Nduaka, C.I.3
Sperling, M.4
Basile, A.S.5
Klamerus, K.J.6
Chi-Burris, K.7
Yan, E.8
Paggiarino, D.A.9
Rosenblatt, I.10
Khan, A.11
Aitchison, R.12
Erlich, S.S.13
-
212
-
-
38749136602
-
Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV)
-
J. DeVincenzo, J.E. Cehelsky, R. Alvarez, S. Elbashir, J. Harborth, I. Toudjarska, L. Nechev, V. Murugaiah, A. Van Vliet, A.K. Vaishnaw, and R. Meyers Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV) Antivir. Res. 77 2008 225 231
-
(2008)
Antivir. Res.
, vol.77
, pp. 225-231
-
-
DeVincenzo, J.1
Cehelsky, J.E.2
Alvarez, R.3
Elbashir, S.4
Harborth, J.5
Toudjarska, I.6
Nechev, L.7
Murugaiah, V.8
Van Vliet, A.9
Vaishnaw, A.K.10
Meyers, R.11
-
217
-
-
84891834550
-
Phase I clinical trial of SYL040012, a small interfering RNA targeting beta-adrenergic receptor 2, for lowering intraocular pressure
-
J. Moreno-Montanes, B. Sadaba, V. Ruz, A. Gomez-Guiu, J. Zarranz, M.V. Gonzalez, C. Paneda, and A.I. Jimenez Phase I clinical trial of SYL040012, a small interfering RNA targeting beta-adrenergic receptor 2, for lowering intraocular pressure Mol. Ther. 22 2014 226 232
-
(2014)
Mol. Ther.
, vol.22
, pp. 226-232
-
-
Moreno-Montanes, J.1
Sadaba, B.2
Ruz, V.3
Gomez-Guiu, A.4
Zarranz, J.5
Gonzalez, M.V.6
Paneda, C.7
Jimenez, A.I.8
-
221
-
-
79960029141
-
Ocular neuroprotection by siRNA targeting caspase-2
-
Z. Ahmed, H. Kalinski, M. Berry, M. Almasieh, H. Ashush, N. Slager, A. Brafman, I. Spivak, N. Prasad, I. Mett, E. Shalom, E. Alpert, A. Di Polo, E. Feinstein, and A. Logan Ocular neuroprotection by siRNA targeting caspase-2 Cell Death Dis. 2 2011 e173
-
(2011)
Cell Death Dis.
, vol.2
, pp. e173
-
-
Ahmed, Z.1
Kalinski, H.2
Berry, M.3
Almasieh, M.4
Ashush, H.5
Slager, N.6
Brafman, A.7
Spivak, I.8
Prasad, N.9
Mett, I.10
Shalom, E.11
Alpert, E.12
Di Polo, A.13
Feinstein, E.14
Logan, A.15
|