Synthetic dsRNA Dicer substrates enhance RNAi potency and efficacy

Nature Biotechnology

Volumn 23, Issue 2, 2005, Pages 222-226

  Kim, Dong Ho ^a   Behlke, Mark A ^b   Rose, Scott D ^b   Chang, Mi Sook ^c   Choi, Sangdun ^c   Rossi, John J ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b INTEGRATED DNA TECHNOLOGIES   (United States)

^c CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOTECHNOLOGY; CONCENTRATION (PROCESS); ENZYMES; FUNCTIONS; GENES; SUBSTRATES; SYNTHESIS (CHEMICAL);

DOUBLE-STRANDED RNA; PROTEIN KINASE; RNA INTERFERENCE; SILENCING;

RNA;

DICER; DOUBLE STRANDED RNA; ENDONUCLEASE; INTERFERON; PROTEIN KINASE R; RECOMBINANT ENZYME; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME SUBSTRATE COMPLEX; GENE SILENCING; GENETIC LINKAGE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE;

GENE EXPRESSION REGULATION; GENE SILENCING; GENE TARGETING; GENETIC ENGINEERING; RIBONUCLEASE III; RNA, SMALL INTERFERING; TRANSFECTION;

ANIMALIA;

EID: 13844281898     PISSN: 10870156     EISSN: None     Source Type: Journal    
DOI: 10.1038/nbt1051     Document Type: Article

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