Controlling fibrous capsule formation through long-term down-regulation of collagen type i (COL1A1) expression by nanofiber-mediated siRNA gene silencing

Acta Biomaterialia

Volumn 9, Issue 1, 2013, Pages 4513-4524

  Rujitanaroj, Pim On ^a   Jao, Brian ^b,c   Yang, Junghoon ^b,c   Wang, Feng ^d   Anderson, James M ^b,c   Wang, Jun ^d   Chew, Sing Yian ^a  

^a Nanyang Technological University   (Singapore)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Case Western Reserve University   (United States)

^d UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Cell penetrating peptides; Electrospinning; Gene knockdown; RNA interference; Scaffold mediated transfection

Indexed keywords

COLLAGEN; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC ENGINEERING; OLIGONUCLEOTIDES; PEPTIDES; RNA; SCAFFOLDS (BIOLOGY);

CELL-PENETRATING PEPTIDE; COLLAGEN TYPE I; DOWN-REGULATION; FIBROUS CAPSULE FORMATION; FOREIGN BODY REACTIONS; GENE KNOCK DOWN; GENE SILENCING; IN-VITRO; RNA INTERFERENCE; SCAFFOLD-MEDIATED TRANSFECTION;

NANOFIBERS;

AMINO ACID DERIVATIVE; COLLAGEN TYPE 1; NANOFIBER; OLIGONUCLEOTIDE; POLY(CAPROLACTONE CO ETHYLETHYLENE PHOSPHATE); SMALL INTERFERING RNA; TISSUE SCAFFOLD; UNCLASSIFIED DRUG;

ARTICLE; DOWN REGULATION; FIBROUS CAPSULE FORMATION; FOREIGN BODY REACTION; GENE EXPRESSION REGULATION; GENE SILENCING; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

EID: 84870239023     PISSN: 17427061     EISSN: 18787568     Source Type: Journal    
DOI: 10.1016/j.actbio.2012.09.029     Document Type: Article

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