Targetable micelleplex hydrogel for long-term, effective, and systemic siRNA delivery

Biomaterials

Volumn 35, Issue 27, 2014, Pages 7970-7977

  Kim, Young Min ^a,b   Song, Soo Chang ^a,b  

^a Korea Institute of Science and Technology   (South Korea)

^b University of Science and Technology (UST)   (South Korea)

Author keywords

Drug delivery; Gene therapy; Hydrogel; Nanoparticle

Indexed keywords

DRUG DELIVERY; GENE THERAPY; GENE TRANSFER; NANOPARTICLES; RNA;

ANTITUMOR EFFECT; CONTROLLED RELEASE; GENE CARRIER; GENE SILENCING; IN-VIVO; POLYMERIC MICELLE; SIRNA DELIVERY;

HYDROGELS;

SMALL INTERFERING RNA; FOLIC ACID; HYDROGEL; MICELLE; ORGANOPHOSPHORUS COMPOUND; POLY(ORGANOPHOSPHAZENE); POLYETHYLENEIMINE; POLYMER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONJUGATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; FEMALE; GENE SILENCING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROGEL; HYDROPHOBICITY; IN VITRO STUDY; MALE; MICELLE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; TARGETABLE MICELLEPLEX HYDROGEL; THERAPY EFFECT; TREATMENT DURATION; ANIMAL; CHEMISTRY; DRUG SCREENING; ENDOCYTOSIS; GENE TRANSFER; METABOLISM; NUDE MOUSE; SYNTHESIS; TIME; TRANSMISSION ELECTRON MICROSCOPY; TUMOR CELL LINE;

ANIMALS; CELL LINE, TUMOR; ENDOCYTOSIS; FOLIC ACID; GENE SILENCING; GENE TRANSFER TECHNIQUES; HUMANS; HYDROGEL; MICE, NUDE; MICELLES; MICROSCOPY, ELECTRON, TRANSMISSION; ORGANOPHOSPHORUS COMPOUNDS; POLYETHYLENEIMINE; POLYMERS; RNA, SMALL INTERFERING; TIME FACTORS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84903449853     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.05.070     Document Type: Article

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