Hyaluronic acid / chitosan multilayer coatings on neuronal implants for localized delivery of siRNA nanoplexes

Journal of Controlled Release

Volumn 168, Issue 3, 2013, Pages 289-297

  Hartmann, Hanna ^a   Hossfeld, Susanne ^a   Schlosshauer, Burkhard ^a   Mittnacht, Ursula ^a   Pêgo, Ana Paula ^c   Dauner, Martin ^d   Doser, Michael ^d   Stoll, Dieter ^a,b   Krastev, Rumen ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b ALBSTADT SIGMARINGEN UNIVERSITY   (Germany)

^c INEB INSTITUTO DE ENGENHARIA BIOMÉDICA   (Portugal)

^d Deutsche Institute für Textil und Faserforschung DITF   (Germany)

Author keywords

Controlled release; Functionalized implants; Nanotherapeutics; Nerve regeneration; Polyelectrolyte multilayers; siRNA nanoplexes

Indexed keywords

CONTROLLED RELEASE; FUNCTIONALIZED; NANOPLEXES; NANOTHERAPEUTICS; NERVE REGENERATION; POLYELECTROLYTE MULTILAYER;

CELL ADHESION; CELL CULTURE; CHITOSAN; DRUG DELIVERY; GENETIC ENGINEERING; HYALURONIC ACID; NEURONS; ORGANIC ACIDS; POLYELECTROLYTES;

MULTILAYERS;

CHITOSAN; HYALURONIC ACID; IMIDAZOLE; NANOPARTICLE; POLYELECTROLYTE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CELL ADHESION; CELL VIABILITY; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG EFFICACY; DRUG STABILITY; MATERIAL COATING; NERVE CELL; NERVE CELL CULTURE; NEUROLOGICAL IMPLANT; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RAT;

ANIMALS; CELL ADHESION; CELL SURVIVAL; CHITOSAN; GENE KNOCKDOWN TECHNIQUES; HYALURONIC ACID; IMIDAZOLES; NANOSTRUCTURES; NEURONS; PC12 CELLS; PROSTHESES AND IMPLANTS; RATS; RHOA GTP-BINDING PROTEIN; RNA, SMALL INTERFERING;

EID: 84877033262     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.03.026     Document Type: Article

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