메뉴 건너뛰기




Volumn 34, Issue 36, 2013, Pages 9201-9209

Enhancing microvascular formation and vessel maturation through temporal control over multiple pro-angiogenic and pro-maturation factors

Author keywords

Angiogenesis; Controlled drug release; Drug delivery; Endothelial cell; Growth factors; Smooth muscle cell

Indexed keywords

ANGIOGENESIS; CONTROLLED DRUG RELEASE; GROWTH FACTOR; PERIPHERAL ARTERY DISEASE; PLATELET-DERIVED GROWTH FACTORS; SMOOTH MUSCLE CELLS; TISSUE ENGINEERED CONSTRUCTS; VASCULAR ENDOTHELIAL GROWTH FACTOR;

EID: 84883780219     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.08.007     Document Type: Article
Times cited : (159)

References (65)
  • 1
    • 67549092003 scopus 로고    scopus 로고
    • Therapeutic angiogenesis in the management of critical limb ischemia: current concepts and review
    • Attanasio S., Snell J. Therapeutic angiogenesis in the management of critical limb ischemia: current concepts and review. Cardiol Rev 2009, 17:115-120.
    • (2009) Cardiol Rev , vol.17 , pp. 115-120
    • Attanasio, S.1    Snell, J.2
  • 2
    • 0034978322 scopus 로고    scopus 로고
    • Therapeutic angiogenesis for ischemic cardiovascular disease
    • Freedman S., Isner J. Therapeutic angiogenesis for ischemic cardiovascular disease. JMol Cell Cardiol 2001, 33:379-393.
    • (2001) JMol Cell Cardiol , vol.33 , pp. 379-393
    • Freedman, S.1    Isner, J.2
  • 3
    • 2942572769 scopus 로고    scopus 로고
    • Therapeutic angiogenesis and vasculogenesis for ischemic disease: part II: cell-based therapies
    • Losordo D., Dimmeler S. Therapeutic angiogenesis and vasculogenesis for ischemic disease: part II: cell-based therapies. Circulation 2004, 109:2692-2697.
    • (2004) Circulation , vol.109 , pp. 2692-2697
    • Losordo, D.1    Dimmeler, S.2
  • 4
    • 34247610438 scopus 로고    scopus 로고
    • Spatiotemporal control of vascular endothelial growth factor delivery from injectable hydrogels enhances angiogenesis
    • Silva E., Mooney D. Spatiotemporal control of vascular endothelial growth factor delivery from injectable hydrogels enhances angiogenesis. JThromb Haemost 2007, 5:590-598.
    • (2007) JThromb Haemost , vol.5 , pp. 590-598
    • Silva, E.1    Mooney, D.2
  • 5
    • 72149100455 scopus 로고    scopus 로고
    • Effects of VEGF temporal and spatial presentation on angiogenesis
    • Silva E., Mooney D. Effects of VEGF temporal and spatial presentation on angiogenesis. Biomaterials 2010, 31:1235-1241.
    • (2010) Biomaterials , vol.31 , pp. 1235-1241
    • Silva, E.1    Mooney, D.2
  • 6
    • 0034076189 scopus 로고    scopus 로고
    • Mechanisms of angiogenesis and arteriogenesis
    • Carmeliet P. Mechanisms of angiogenesis and arteriogenesis. Nat Med 2000, 6:389-395.
    • (2000) Nat Med , vol.6 , pp. 389-395
    • Carmeliet, P.1
  • 7
    • 0038376002 scopus 로고    scopus 로고
    • Molecular regulation of vessel maturation
    • Jain R. Molecular regulation of vessel maturation. Nat Med 2003, 9:685-693.
    • (2003) Nat Med , vol.9 , pp. 685-693
    • Jain, R.1
  • 8
    • 84861801210 scopus 로고    scopus 로고
    • Therapeutic angiogenesis: controlled delivery of angiogenic factors
    • Chu H., Wang Y. Therapeutic angiogenesis: controlled delivery of angiogenic factors. Ther Deliv 2012, 3:693-714.
    • (2012) Ther Deliv , vol.3 , pp. 693-714
    • Chu, H.1    Wang, Y.2
  • 9
    • 0035895737 scopus 로고    scopus 로고
    • Molecular mechanisms of blood vessel growth
    • Conway E., Collen D., Carmeliet P. Molecular mechanisms of blood vessel growth. Cardiovasc Res 2001, 49:507-521.
    • (2001) Cardiovasc Res , vol.49 , pp. 507-521
    • Conway, E.1    Collen, D.2    Carmeliet, P.3
  • 10
    • 0034796595 scopus 로고    scopus 로고
    • Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy
    • Jain R. Normalizing tumor vasculature with anti-angiogenic therapy: a new paradigm for combination therapy. Nat Med 2001, 7:987-989.
    • (2001) Nat Med , vol.7 , pp. 987-989
    • Jain, R.1
  • 11
    • 0035044630 scopus 로고    scopus 로고
    • Invitro models of vasculogenesis and angiogenesis
    • Vailhé B., Vittet D., Feige J. Invitro models of vasculogenesis and angiogenesis. Lab Invest 2001, 81:439-452.
    • (2001) Lab Invest , vol.81 , pp. 439-452
    • Vailhé, B.1    Vittet, D.2    Feige, J.3
  • 12
    • 77957302220 scopus 로고    scopus 로고
    • Modulating notch signaling to enhance neovascularization and reperfusion in diabetic mice
    • Cao L., Arany P., Kim J., Rivera-Feliciano J., Wang Y.-S., He Z., et al. Modulating notch signaling to enhance neovascularization and reperfusion in diabetic mice. Biomaterials 2010, 31:9048-9056.
    • (2010) Biomaterials , vol.31 , pp. 9048-9056
    • Cao, L.1    Arany, P.2    Kim, J.3    Rivera-Feliciano, J.4    Wang, Y.-S.5    He, Z.6
  • 13
    • 67649867959 scopus 로고    scopus 로고
    • Promoting angiogenesis via manipulation of VEGF responsiveness with notch signaling
    • Cao L., Arany P., Wang Y.-S., Mooney D. Promoting angiogenesis via manipulation of VEGF responsiveness with notch signaling. Biomaterials 2009, 30:4085-4093.
    • (2009) Biomaterials , vol.30 , pp. 4085-4093
    • Cao, L.1    Arany, P.2    Wang, Y.-S.3    Mooney, D.4
  • 14
    • 36049046711 scopus 로고    scopus 로고
    • Spatiotemporal control over growth factor signaling for therapeutic neovascularization
    • Cao L., Mooney D. Spatiotemporal control over growth factor signaling for therapeutic neovascularization. Adv Drug Deliv Rev 2007, 59:1340-1350.
    • (2007) Adv Drug Deliv Rev , vol.59 , pp. 1340-1350
    • Cao, L.1    Mooney, D.2
  • 15
    • 33846050010 scopus 로고    scopus 로고
    • Spatio-temporal VEGF and PDGF delivery patterns blood vessel formation and maturation
    • Chen R., Silva E., Yuen W., Mooney D. Spatio-temporal VEGF and PDGF delivery patterns blood vessel formation and maturation. Pharm Res 2007, 24:258-264.
    • (2007) Pharm Res , vol.24 , pp. 258-264
    • Chen, R.1    Silva, E.2    Yuen, W.3    Mooney, D.4
  • 16
    • 70349313632 scopus 로고    scopus 로고
    • Cyclic tensile strain triggers asequence of autocrine and paracrine signaling to regulate angiogenic sprouting in human vascular cells
    • Yung Y., Chae J., Buehler M., Hunter C., Mooney D. Cyclic tensile strain triggers asequence of autocrine and paracrine signaling to regulate angiogenic sprouting in human vascular cells. Proc Natl Acad Sci U S A 2009, 106:15279-15284.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 15279-15284
    • Yung, Y.1    Chae, J.2    Buehler, M.3    Hunter, C.4    Mooney, D.5
  • 17
    • 27144445057 scopus 로고    scopus 로고
    • Invitro evaluation of the angiostatic potential of drugs using an endothelialized tissue-engineered connective tissue
    • Tremblay P.-L., Berthod F., Germain L., Auger F. Invitro evaluation of the angiostatic potential of drugs using an endothelialized tissue-engineered connective tissue. JPharmacol Exp Ther 2005, 315:510-516.
    • (2005) JPharmacol Exp Ther , vol.315 , pp. 510-516
    • Tremblay, P.-L.1    Berthod, F.2    Germain, L.3    Auger, F.4
  • 18
    • 0027236943 scopus 로고
    • The 16-kilodalton N-terminal fragment of human prolactin is a potent inhibitor of angiogenesis
    • Clapp C., Martial J., Guzman R., Rentier-Delure F., Weiner R. The 16-kilodalton N-terminal fragment of human prolactin is a potent inhibitor of angiogenesis. Endocrinology 1993, 133:1292-1299.
    • (1993) Endocrinology , vol.133 , pp. 1292-1299
    • Clapp, C.1    Martial, J.2    Guzman, R.3    Rentier-Delure, F.4    Weiner, R.5
  • 19
    • 78149259034 scopus 로고    scopus 로고
    • Mimicking nature by codelivery of stimulant and inhibitor to create temporally stable and spatially restricted angiogenic zones
    • Yuen W., Du N., Chan C., Silva E., Mooney D. Mimicking nature by codelivery of stimulant and inhibitor to create temporally stable and spatially restricted angiogenic zones. Proc Natl Acad Sci U S A 2010, 107:17933-17938.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 17933-17938
    • Yuen, W.1    Du, N.2    Chan, C.3    Silva, E.4    Mooney, D.5
  • 20
    • 0034009912 scopus 로고    scopus 로고
    • An invitro model for the study of human bone marrow angiogenesis: role of hematopoietic cytokines
    • Pelletier L., Regnard J., Fellmann D., Charbord P. An invitro model for the study of human bone marrow angiogenesis: role of hematopoietic cytokines. Lab Invest 2000, 80:501-511.
    • (2000) Lab Invest , vol.80 , pp. 501-511
    • Pelletier, L.1    Regnard, J.2    Fellmann, D.3    Charbord, P.4
  • 21
    • 0035121532 scopus 로고    scopus 로고
    • Blood vessel maturation in a 3-dimensional spheroidal coculture model: direct contact with smooth muscle cells regulates endothelial cell quiescence and abrogates VEGF responsiveness
    • Korff T., Kimmina S., Martiny-Baron G., Augustin H. Blood vessel maturation in a 3-dimensional spheroidal coculture model: direct contact with smooth muscle cells regulates endothelial cell quiescence and abrogates VEGF responsiveness. FASEB J 2001, 15:447-457.
    • (2001) FASEB J , vol.15 , pp. 447-457
    • Korff, T.1    Kimmina, S.2    Martiny-Baron, G.3    Augustin, H.4
  • 22
    • 0023585264 scopus 로고
    • Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells
    • Orlidge A., D'Amore P. Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells. JCell Biol 1987, 105:1455-1462.
    • (1987) JCell Biol , vol.105 , pp. 1455-1462
    • Orlidge, A.1    D'Amore, P.2
  • 23
    • 0035972251 scopus 로고    scopus 로고
    • Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis
    • Hellström M., Gerhardt H., Kalén M., Li X., Eriksson U., Wolburg H., et al. Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. JCell Biol 2001, 153:543-553.
    • (2001) JCell Biol , vol.153 , pp. 543-553
    • Hellström, M.1    Gerhardt, H.2    Kalén, M.3    Li, X.4    Eriksson, U.5    Wolburg, H.6
  • 24
    • 0021824956 scopus 로고
    • Microvascular pericytes contain muscle and nonmuscle actins
    • Herman I., D'Amore P. Microvascular pericytes contain muscle and nonmuscle actins. JCell Biol 1985, 101:43-52.
    • (1985) JCell Biol , vol.101 , pp. 43-52
    • Herman, I.1    D'Amore, P.2
  • 25
    • 33749860102 scopus 로고    scopus 로고
    • Bidirectional control of CNS capillary diameter by pericytes
    • Peppiatt C., Howarth C., Mobbs P., Attwell D. Bidirectional control of CNS capillary diameter by pericytes. Nature 2006, 443:700-704.
    • (2006) Nature , vol.443 , pp. 700-704
    • Peppiatt, C.1    Howarth, C.2    Mobbs, P.3    Attwell, D.4
  • 26
    • 69949172891 scopus 로고    scopus 로고
    • Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery
    • Yemisci M., Gursoy-Ozdemir Y., Vural A., Can A., Topalkara K., Dalkara T. Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery. Nat Med 2009, 15:1031-1037.
    • (2009) Nat Med , vol.15 , pp. 1031-1037
    • Yemisci, M.1    Gursoy-Ozdemir, Y.2    Vural, A.3    Can, A.4    Topalkara, K.5    Dalkara, T.6
  • 27
    • 64049085365 scopus 로고    scopus 로고
    • The pericyte: cellular regulator of microvascular blood flow
    • Kutcher M., Herman I. The pericyte: cellular regulator of microvascular blood flow. Microvasc Res 2009, 77:235-246.
    • (2009) Microvasc Res , vol.77 , pp. 235-246
    • Kutcher, M.1    Herman, I.2
  • 28
    • 0024462648 scopus 로고
    • Influence of pericytes on capillary endothelial cell growth
    • Antonelli-Orlidge A., Smith S., D'Amore P. Influence of pericytes on capillary endothelial cell growth. Am Rev Respir Dis 1989, 140:1129-1131.
    • (1989) Am Rev Respir Dis , vol.140 , pp. 1129-1131
    • Antonelli-Orlidge, A.1    Smith, S.2    D'Amore, P.3
  • 29
    • 0242456268 scopus 로고    scopus 로고
    • Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival
    • Darland D., Massingham L., Smith S., Piek E., Saint-Geniez M., D'Amore P. Pericyte production of cell-associated VEGF is differentiation-dependent and is associated with endothelial survival. Dev Biol 2003, 264:275-288.
    • (2003) Dev Biol , vol.264 , pp. 275-288
    • Darland, D.1    Massingham, L.2    Smith, S.3    Piek, E.4    Saint-Geniez, M.5    D'Amore, P.6
  • 30
    • 26944437515 scopus 로고    scopus 로고
    • PDGFRbeta+ perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival
    • Song S., Ewald A., Stallcup W., Werb Z., Bergers G. PDGFRbeta+ perivascular progenitor cells in tumours regulate pericyte differentiation and vascular survival. Nat Cell Biol 2005, 7:870-879.
    • (2005) Nat Cell Biol , vol.7 , pp. 870-879
    • Song, S.1    Ewald, A.2    Stallcup, W.3    Werb, Z.4    Bergers, G.5
  • 31
    • 0242405617 scopus 로고    scopus 로고
    • Endothelial-pericyte interactions in angiogenesis
    • Gerhardt H., Betsholtz C. Endothelial-pericyte interactions in angiogenesis. Cell Tissue Res 2003, 314:15-23.
    • (2003) Cell Tissue Res , vol.314 , pp. 15-23
    • Gerhardt, H.1    Betsholtz, C.2
  • 33
    • 80053120328 scopus 로고    scopus 로고
    • The role of multifunctional delivery scaffold in the ability of cultured myoblasts to promote muscle regeneration
    • Borselli C., Cezar C., Shvartsman D., Vandenburgh H., Mooney D. The role of multifunctional delivery scaffold in the ability of cultured myoblasts to promote muscle regeneration. Biomaterials 2011, 32:8905-8914.
    • (2011) Biomaterials , vol.32 , pp. 8905-8914
    • Borselli, C.1    Cezar, C.2    Shvartsman, D.3    Vandenburgh, H.4    Mooney, D.5
  • 34
    • 84863338473 scopus 로고    scopus 로고
    • Combined VEGF and PDGF treatment reduces secondary degeneration after spinal cord injury
    • Lutton C., Young Y., Williams R., Meedeniya A., Mackay-Sim A., Goss B. Combined VEGF and PDGF treatment reduces secondary degeneration after spinal cord injury. JNeurotrauma 2012, 29:957-970.
    • (2012) JNeurotrauma , vol.29 , pp. 957-970
    • Lutton, C.1    Young, Y.2    Williams, R.3    Meedeniya, A.4    Mackay-Sim, A.5    Goss, B.6
  • 35
    • 84857361387 scopus 로고    scopus 로고
    • Effect of triple growth factor controlled delivery by a brushite-PLGA system on a bone defect
    • Reyes R., De la Riva B., Delgado A., Hernández A., Sánchez E., Évora C. Effect of triple growth factor controlled delivery by a brushite-PLGA system on a bone defect. Injury 2012, 43:334-342.
    • (2012) Injury , vol.43 , pp. 334-342
    • Reyes, R.1    De la Riva, B.2    Delgado, A.3    Hernández, A.4    Sánchez, E.5    Évora, C.6
  • 37
    • 0038363443 scopus 로고    scopus 로고
    • Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2
    • Cao R., Bråkenhielm E., Pawliuk R., Wariaro D., Post M., Wahlberg E., et al. Angiogenic synergism, vascular stability and improvement of hind-limb ischemia by a combination of PDGF-BB and FGF-2. Nat Med 2003, 9:604-613.
    • (2003) Nat Med , vol.9 , pp. 604-613
    • Cao, R.1    Bråkenhielm, E.2    Pawliuk, R.3    Wariaro, D.4    Post, M.5    Wahlberg, E.6
  • 38
    • 0032890051 scopus 로고    scopus 로고
    • Vascular endothelial growth factor: molecular and biological aspects
    • Ferrara N. Vascular endothelial growth factor: molecular and biological aspects. Curr Top Microbiol Immunol 1999, 237:1-30.
    • (1999) Curr Top Microbiol Immunol , vol.237 , pp. 1-30
    • Ferrara, N.1
  • 39
    • 0033636357 scopus 로고    scopus 로고
    • VEGF: an update on biological and therapeutic aspects
    • Ferrara N. VEGF: an update on biological and therapeutic aspects. Curr Opin Biotechnol 2000, 11:617-624.
    • (2000) Curr Opin Biotechnol , vol.11 , pp. 617-624
    • Ferrara, N.1
  • 40
    • 84855393083 scopus 로고    scopus 로고
    • Sustaining neovascularization of a scaffold through staged release of vascular endothelial growth factor-A and platelet-derived growth factor-BB
    • Davies N., Schmidt C., Bezuidenhout D., Zilla P. Sustaining neovascularization of a scaffold through staged release of vascular endothelial growth factor-A and platelet-derived growth factor-BB. Tissue Eng Part A 2012, 18:26-34.
    • (2012) Tissue Eng Part A , vol.18 , pp. 26-34
    • Davies, N.1    Schmidt, C.2    Bezuidenhout, D.3    Zilla, P.4
  • 41
    • 79960096827 scopus 로고    scopus 로고
    • Normalization of the vasculature for treatment of cancer and other diseases
    • Goel S., Duda D., Xu L., Munn L., Boucher Y., Fukumura D., et al. Normalization of the vasculature for treatment of cancer and other diseases. Physiol Rev 2011, 91:1071-1121.
    • (2011) Physiol Rev , vol.91 , pp. 1071-1121
    • Goel, S.1    Duda, D.2    Xu, L.3    Munn, L.4    Boucher, Y.5    Fukumura, D.6
  • 42
    • 0032918412 scopus 로고    scopus 로고
    • Blood vessel maturation: vascular development comes of age
    • Darland D., D'Amore P. Blood vessel maturation: vascular development comes of age. JClin Invest 1999, 103:157-158.
    • (1999) JClin Invest , vol.103 , pp. 157-158
    • Darland, D.1    D'Amore, P.2
  • 43
    • 0345798150 scopus 로고    scopus 로고
    • Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors
    • Abramsson A., Lindblom P., Betsholtz C. Endothelial and nonendothelial sources of PDGF-B regulate pericyte recruitment and influence vascular pattern formation in tumors. JClin Invest 2003, 112:1142-1151.
    • (2003) JClin Invest , vol.112 , pp. 1142-1151
    • Abramsson, A.1    Lindblom, P.2    Betsholtz, C.3
  • 44
    • 68049140803 scopus 로고    scopus 로고
    • Overexpression of platelet-derived growth factor-BB increases tumor pericyte content via stromal-derived factor-1alpha/CXCR4 axis
    • Song N., Huang Y., Shi H., Yuan S., Ding Y., Song X., et al. Overexpression of platelet-derived growth factor-BB increases tumor pericyte content via stromal-derived factor-1alpha/CXCR4 axis. Cancer Res 2009, 69:6057-6064.
    • (2009) Cancer Res , vol.69 , pp. 6057-6064
    • Song, N.1    Huang, Y.2    Shi, H.3    Yuan, S.4    Ding, Y.5    Song, X.6
  • 45
    • 0032768156 scopus 로고    scopus 로고
    • Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse
    • Hellström M., Kalén M., Lindahl P., Abramsson A., Betsholtz C. Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development 1999, 126:3047-3055.
    • (1999) Development , vol.126 , pp. 3047-3055
    • Hellström, M.1    Kalén, M.2    Lindahl, P.3    Abramsson, A.4    Betsholtz, C.5
  • 46
    • 0032890359 scopus 로고    scopus 로고
    • The angiopoietins: Yin and Yang in angiogenesis
    • Davis S., Yancopoulos G. The angiopoietins: Yin and Yang in angiogenesis. Curr Top Microbiol Immunol 1999, 237:173-185.
    • (1999) Curr Top Microbiol Immunol , vol.237 , pp. 173-185
    • Davis, S.1    Yancopoulos, G.2
  • 47
    • 0033135876 scopus 로고    scopus 로고
    • Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development
    • Gale N., Yancopoulos G. Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development. Genes Dev 1999, 13:1055-1066.
    • (1999) Genes Dev , vol.13 , pp. 1055-1066
    • Gale, N.1    Yancopoulos, G.2
  • 49
    • 57649135172 scopus 로고    scopus 로고
    • Arole for VEGF as a negative regulator of pericyte function and vessel maturation
    • Greenberg J., Shields D., Barillas S., Acevedo L., Murphy E., Huang J., et al. Arole for VEGF as a negative regulator of pericyte function and vessel maturation. Nature 2008, 456:809-813.
    • (2008) Nature , vol.456 , pp. 809-813
    • Greenberg, J.1    Shields, D.2    Barillas, S.3    Acevedo, L.4    Murphy, E.5    Huang, J.6
  • 50
    • 0025735802 scopus 로고
    • Controlled and modulated release of basic fibroblast growth factor
    • Edelman E., Mathiowitz E., Langer R., Klagsbrun M. Controlled and modulated release of basic fibroblast growth factor. Biomaterials 1991, 12:619-626.
    • (1991) Biomaterials , vol.12 , pp. 619-626
    • Edelman, E.1    Mathiowitz, E.2    Langer, R.3    Klagsbrun, M.4
  • 51
    • 0029335538 scopus 로고
    • Biodegradable polymers for protein and peptide drug delivery
    • Gombotz W., Pettit D. Biodegradable polymers for protein and peptide drug delivery. Bioconjug Chem 1995, 6:332-351.
    • (1995) Bioconjug Chem , vol.6 , pp. 332-351
    • Gombotz, W.1    Pettit, D.2
  • 52
    • 0029876486 scopus 로고    scopus 로고
    • Novel systems for controlled delivery of macromolecules
    • Kuo P., Saltzman W. Novel systems for controlled delivery of macromolecules. Crit Rev Eukaryot Gene Expr 1996, 6:59-73.
    • (1996) Crit Rev Eukaryot Gene Expr , vol.6 , pp. 59-73
    • Kuo, P.1    Saltzman, W.2
  • 53
    • 0032580354 scopus 로고    scopus 로고
    • Drug delivery and targeting
    • Langer R. Drug delivery and targeting. Nature 1998, 392:5-10.
    • (1998) Nature , vol.392 , pp. 5-10
    • Langer, R.1
  • 54
    • 0034700503 scopus 로고    scopus 로고
    • Controlled growth factor release from synthetic extracellular matrices
    • Lee K., Peters M., Anderson K., Mooney D. Controlled growth factor release from synthetic extracellular matrices. Nature 2000, 408:998-1000.
    • (2000) Nature , vol.408 , pp. 998-1000
    • Lee, K.1    Peters, M.2    Anderson, K.3    Mooney, D.4
  • 55
    • 0033551142 scopus 로고    scopus 로고
    • Millimeter-scale positioning of a nerve-growth-factor source and biological activity in the brain
    • Mahoney M., Saltzman W. Millimeter-scale positioning of a nerve-growth-factor source and biological activity in the brain. Proc Natl Acad Sci U S A 1999, 96:4536-4539.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 4536-4539
    • Mahoney, M.1    Saltzman, W.2
  • 56
    • 0021709939 scopus 로고
    • Controlled release of microquantities of macromolecules
    • Murray J., Brown L., Langer R. Controlled release of microquantities of macromolecules. Cancer Drug Deliv 1984, 1:119-123.
    • (1984) Cancer Drug Deliv , vol.1 , pp. 119-123
    • Murray, J.1    Brown, L.2    Langer, R.3
  • 57
    • 1342346686 scopus 로고    scopus 로고
    • Spatial and temporal control of angiogenesis and arterialization using focal applications of VEGF164 and Ang-1
    • Peirce S., Price R., Skalak T. Spatial and temporal control of angiogenesis and arterialization using focal applications of VEGF164 and Ang-1. Am J Physiol Heart Circ Physiol 2004, 286:25.
    • (2004) Am J Physiol Heart Circ Physiol , vol.286 , pp. 25
    • Peirce, S.1    Price, R.2    Skalak, T.3
  • 58
    • 33749015187 scopus 로고    scopus 로고
    • Temporally regulated delivery of VEGF invitro and invivo
    • Ennett A., Kaigler D., Mooney D. Temporally regulated delivery of VEGF invitro and invivo. JBiomed Mater Res A 2006, 79:176-184.
    • (2006) JBiomed Mater Res A , vol.79 , pp. 176-184
    • Ennett, A.1    Kaigler, D.2    Mooney, D.3
  • 59
    • 0031834239 scopus 로고    scopus 로고
    • Aplasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
    • Benjamin L., Hemo I., Keshet E. Aplasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 1998, 125:1591-1598.
    • (1998) Development , vol.125 , pp. 1591-1598
    • Benjamin, L.1    Hemo, I.2    Keshet, E.3
  • 61
    • 14944377120 scopus 로고    scopus 로고
    • The Tie-2 ligand angiopoietin-2 destabilizes quiescent endothelium through an internal autocrine loop mechanism
    • Scharpfenecker M., Fiedler U., Reiss Y., Augustin H. The Tie-2 ligand angiopoietin-2 destabilizes quiescent endothelium through an internal autocrine loop mechanism. JCell Sci 2005, 118:771-780.
    • (2005) JCell Sci , vol.118 , pp. 771-780
    • Scharpfenecker, M.1    Fiedler, U.2    Reiss, Y.3    Augustin, H.4
  • 62
    • 28144445732 scopus 로고    scopus 로고
    • Angiopoietin 2 displays a vascular endothelial growth factor dependent synergistic effect in hepatocellular carcinoma development in mice
    • Yoshiji H., Kuriyama S., Noguchi R., Yoshii J., Ikenaka Y., Yanase K., et al. Angiopoietin 2 displays a vascular endothelial growth factor dependent synergistic effect in hepatocellular carcinoma development in mice. Gut 2005, 54:1768-1775.
    • (2005) Gut , vol.54 , pp. 1768-1775
    • Yoshiji, H.1    Kuriyama, S.2    Noguchi, R.3    Yoshii, J.4    Ikenaka, Y.5    Yanase, K.6
  • 63
    • 1942455227 scopus 로고    scopus 로고
    • Apericyte-derived angiopoietin-1 multimeric complex induces occludin gene expression in brain capillary endothelial cells through Tie-2 activation invitro
    • Hori S., Ohtsuki S., Hosoya K.-i., Nakashima E., Terasaki T. Apericyte-derived angiopoietin-1 multimeric complex induces occludin gene expression in brain capillary endothelial cells through Tie-2 activation invitro. JNeurochem 2004, 89:503-513.
    • (2004) JNeurochem , vol.89 , pp. 503-513
    • Hori, S.1    Ohtsuki, S.2    Hosoya, K.-I.3    Nakashima, E.4    Terasaki, T.5
  • 64
    • 0036223819 scopus 로고    scopus 로고
    • Stable expression of angiopoietin-1 and other markers by cultured pericytes: phenotypic similarities to a subpopulation of cells in maturing vessels during later stages of angiogenesis invivo
    • Sundberg C., Kowanetz M., Brown L., Detmar M., Dvorak H. Stable expression of angiopoietin-1 and other markers by cultured pericytes: phenotypic similarities to a subpopulation of cells in maturing vessels during later stages of angiogenesis invivo. Lab Invest 2002, 82:387-401.
    • (2002) Lab Invest , vol.82 , pp. 387-401
    • Sundberg, C.1    Kowanetz, M.2    Brown, L.3    Detmar, M.4    Dvorak, H.5
  • 65
    • 0036896814 scopus 로고    scopus 로고
    • Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells
    • Uemura A., Ogawa M., Hirashima M., Fujiwara T., Koyama S., Takagi H., et al. Recombinant angiopoietin-1 restores higher-order architecture of growing blood vessels in mice in the absence of mural cells. JClin Invest 2002, 110:1619-1628.
    • (2002) JClin Invest , vol.110 , pp. 1619-1628
    • Uemura, A.1    Ogawa, M.2    Hirashima, M.3    Fujiwara, T.4    Koyama, S.5    Takagi, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.