Exploring polyethylenimine-mediated DNA transfection and the proton sponge hypothesis

Journal of Gene Medicine

Volumn 7, Issue 5, 2005, Pages 657-663

  Akinc, Akin ^a   Thomas, Mini ^b   Klibanov, Alexander M ^b   Langer, Robert ^a  

^a USA   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Gene delivery; Lysosome; Polyethylenimine (PEI); Proton sponge; Transfection

Indexed keywords

BAFILOMYCIN A1; CHLOROQUINE; DNA; PLASMID VECTOR; POLYETHYLENEIMINE; POLYLYSINE;

ACIDITY; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CELL PH; CELL TRANSPORT; CONTROLLED STUDY; DNA BINDING; DNA TRANSFECTION; DNA TRANSFER; HYPOTHESIS; LYSOSOME; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; NONVIRAL GENE THERAPY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS;

ANIMALS; ANTI-BACTERIAL AGENTS; CERCOPITHECUS AETHIOPS; CHLOROQUINE; COS CELLS; CYTOPLASM; DNA; ENDOSOMES; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HYDROGEN-ION CONCENTRATION; LUCIFERASES; MACROLIDES; POLYETHYLENEIMINE; POLYLYSINE; POLYMERS; PROTON PUMPS;

EID: 19744372388     PISSN: 1099498X     EISSN: None     Source Type: Journal    
DOI: 10.1002/jgm.696     Document Type: Article

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